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Journal articles on the topic 'Hyperaesthetic'

Author: Grafiati

Published: 4 June 2025

Last updated: 15 July 2025

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BING., H. I. "Rudimentary Hyperaesthetic Zones of the Abdomen1." Acta Medica Scandinavica 82, no. 3-4 (2009): 338–41. http://dx.doi.org/10.1111/j.0954-6820.1934.tb09410.x.

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Livesley, W. John, and Malcolm West. "The DSM-III Distinction between Schizoid and Avoidant Personality Disorders." Canadian Journal of Psychiatry 31, no. 1 (1986): 59–62. http://dx.doi.org/10.1177/070674378603100112.

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The DSM-III distinction between schizoid and avoidant personality disorders is examined. This distinction derives from Mi/Ion's bio-social learning theory and his interpretation of Kretschmer's personality types. Kretschmer's depiction of schizoid personality emphasizes the ratio between hyperaesthetic and anaesthetic tendencies. It is argued, therefore, that the division of this continuous distribution into two distinct personality disorders is historically inaccurate. Clinical case material is used to illustrate this misconception.

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Goodale, Elizabeth C., Stephen D. White, Catherine A. Outerbridge, Angela D. Everett, and Verena K. Affolter. "A retrospective review of hyperaesthetic leucotrichia in horses in the USA." Veterinary Dermatology 27, no. 4 (2016): 294—e72. http://dx.doi.org/10.1111/vde.12327.

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Lars, Christian Grabbe. "The Hyperaesthetics of Technology." Art Style, Art & Culture International Magazine 3, no. 3 (2019): 39–49. https://doi.org/10.5281/zenodo.4116518.

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Art Style | Art & Culture International Magazine Abstract Analog and digital technologies are an immanent part of postmodern lifeworld’s around the globe, and they are a fundament or – in some cases – driving force for mass media, telecommunication, art, and design. This omnipresence and ordinariness of technology make it very difficult to take sides: the defender determines a specific value of technology for creative processes and the opponent proclaims a general worthlessness of technology for artistic creation. This essay focusses not on different judgements, but it will analyze some important aspects of the structural dynamic of technology in the context of a creative mediatization. This means, that a work of art, a design concept or a communication medium has to be understand as a specific aesthetic artefact that enables a perceptual relation or interaction of a technological repertoire, a specific mode of representation and a sensory awareness of the recipient. This interconnection can be understood within a phenosemiotic sign relation that allows an analytical structuring of aesthetic processes as embodied and perceptual processes. This phenosemiotic analysis gives insights in the specific interconnectedness of technological processes, sensory and perceptual dynamics and the construction of meaning in a cognitive perspective that is always embedded in the bodily processes of reception. Additionally, the phensosemiotic framework is also able to give insights into a possible redefinition or enhancement of the concept of aesthetics in general, which is highly correlated with the sensory processes of the recipient: This means, that postmodern artefacts of mediatization are more and more pushing the boundaries of perception and are simultaneously expanding the structural horizon of a classical aesthetics toward a technological-driven hyperaesthetics.

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Mohd Yusuf, Salma, Ilham Ameera Ismail, Rumihati Abdul Hamid, Nur Adliah Jamil, and Mazapuspavina Md Yasin. "Isolated Bilateral Pinna Swelling: A Rare Initial Presentation of Leprosy." Open Access Macedonian Journal of Medical Sciences 7, no. 11 (2019): 1815–17. http://dx.doi.org/10.3889/oamjms.2019.481.

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BACKGROUND: Leprosy or Hansen disease is a chronic infectious disease that causes social stigma due to its deforming bodily appearance and physical disability. It has a wide spectrum of presentation affecting diagnosis.CASE REPORT: A 21-year-old man who presented with chronic isolated bilateral pinna swelling as a result of leprosy is reported. The bilateral pinna swelling started as multiple shiny papules with an erythematous background and progressively became hyperpigmented and lobular over two years. This rare presentation of leprosy poses initial diagnostic difficulties, leading to misdiagnoses by various health care professionals. Diagnoses ascribed include eczema, insect bite and perichondritis. A suspicion of leprosy was raised when hyperaesthetic hypopigmentation of skin started to appear on the body after two years, with worsening of the pinna swellings. This was confirmed by identification of Mycobacterium leprae in slit skin smear test and skin biopsy.CONCLUSION: Isolated involvement of pinna in a patient without lesions in other body parts is an unusual initial presentation of leprosy. However, leprosy should be kept as a rare differential diagnosis of isolated lesions on the ear in patients not responding to conventional treatment.

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BRADSHAW, J. L. "Allodynia: a sensory analogue of motor mirror neurons in a hyperaesthetic patient reporting instantaneous discomfort to another's perceived sudden minor injury?" Journal of Neurology, Neurosurgery & Psychiatry 70, no. 1 (2001): 135a—136. http://dx.doi.org/10.1136/jnnp.70.1.135a.

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Grapes, Nicholas John, Rowena Mary Anne Packer, and Steven De Decker. "Clinical reasoning in canine cervical hyperaesthesia: which presenting features are important?" Veterinary Record 187, no. 11 (2020): 448. http://dx.doi.org/10.1136/vr.105818.

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BackgroundTo evaluate whether clinical features from the history, presentation, physical and neurological examination of dogs with cervical hyperaesthesia are statistically predictive of the underlying diagnosis.MethodsTwo hundred and ninety-eight dogs presenting with cervical hyperaesthesia between January 2010 and October 2018 were investigated. Only neurologically normal dogs with cervical hyperaesthesia on examination were included, while those with concurrent neurological deficits including gait abnormalities and proprioceptive deficits were excluded. Univariate analysis of clinical variables was performed, and those associated with each diagnosis were retained for multivariable binary logistic regression models.ResultsNinety-five per cent of cervical hyperaesthesia presentations were represented by eight conditions that included steroid-responsive meningitis arteritis (SRMA; n=100), intervertebral disc extrusion (n=78), syringomyelia (SM; n=51), intervertebral disc protrusion (n=30), neoplasia (n=8), cervical spondylomyelopathy (n=7), immune-mediated polyarthritis (n=5) and meningoencephalomyelitis of unknown aetiology (n=5). Younger age (P=0.003), pyrexia (P=0.003) and haematology abnormalities (P=0.03) comprising leucocytosis, neutrophilia or monocytosis were associated with a diagnosis of SRMA.ConclusionsEasy-to-recognise clinical features can be used to identify the most likely differential diagnosis in neurologically normal dogs with cervical hyperaesthesia, which may aid the decision making of veterinary surgeons evaluating dogs with this presentation.

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Amarnath Gupta and A P Singh. "A Study to Evaluate the Significance of Sherren’s Triangle Hyperaesthesia in a Treatment of Acute Appendicitis." Academia Journal of Surgery 3, no. 1 (2020): 12–15. http://dx.doi.org/10.47008/ajs/2020.3.1.3.

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Background: Acute appendicitis is the most common surgical emergency. In spite of sophisticated new investigations mainstay of diagnosis depends on clinical sign and symptoms, Sherren‘s triangle hyperaesthesia is very important sign with controversial efficacy about it in available literature. The aim of this study was to explore the significance of hyperaesthesia in Sherren’s triangle in a treatment of acute appendicitis. Subjects and Methods: This study was conducted in 418 patients with 186 females and 251 males. Patients were of acute appendicitis operated for appendicectomy included in the study. Results: Sensitivity and specificity of hyperaesthesia in Sherren’s triangle were 47.7% and 42.9% respectively with positive and negative predictive values were 92.1% and 5.56%. Conclusion: Hence it indicates that hyperaesthesia in Sherren’s triangle is important sign to suspect to support diagnosis of acute appendicitis. It has minimal significance to rule out it. This sign plays very important role in a diagnosis of complicated appendicitis like obstructive appendicitis.

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Taylor, Pamela G. "Hyperaesthetics: Making Sense of Our Technomediated World." Studies in Art Education 45, no. 4 (2004): 328–42. http://dx.doi.org/10.1080/00393541.2004.11651779.

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Colebunders, R., E. De Droogh, K. Depraetere, Y. Pelgrom, and P. De Jonghe. "Painful hyperaesthesia caused by protease inhibitors?" Infection 26, no. 4 (1998): 250–51. http://dx.doi.org/10.1007/bf02962375.

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Lamture, Yashwant R., Harshal Ramteke, and Varsha Gajbhiye. "Sherren`s triangle hyperaesthesia a tool to rule out complicated appendicitis." International Surgery Journal 5, no. 7 (2018): 2563. http://dx.doi.org/10.18203/2349-2902.isj20182774.

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Background: Acute appendicitis is the most common surgical emergency. In spite of sophisticated new investigations mainstay of diagnosis depends on clinical sign and symptoms, Sherren`s triangle hyperaesthesia is very important sign with controversial efficacy about it in available literature. Hence this study was undertaken to prove its efficacy of it.Methods: This study was conducted in 418 patients with 186 females and 251 males. Patients were of acute appendicitis operated for appendicectomy included in the study. Data analysis was done by data statistic software.Results: Sensitivity and specificity of hyperaesthesia in Sherren’s triangle were 47.7% and 42.9% respectively with positive and negative predictive values were 92.1% and 5.56%.Conclusions: Hence it indicates that hyperaesthesia in Sherren’s triangle is important sign to suspect to support diagnosis of acute appendicitis. It has minimal significance to rule out it. This sign plays very important role in a diagnosis of complicated appendicitis like obstructive appendicitis.

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Ooi, Catriona, and Vijay Zawar. "Hyperaesthesia Following Genital Herpes: A Case Report." Dermatology Research and Practice 2011 (2011): 1–3. http://dx.doi.org/10.1155/2011/903595.

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We report an adult female patient who presented with sacral radiculopathy as incapacitating dysthesias following primary genital herpes simplex, which later recurred. Despite use of systemic antiviral treatment, the painful syndrome in our patient persisted. The success in treatment was seen only after the addition of amitriptyline hydrochloride. The case is being presented here for its rare manifestation and novel use of amitriptyline hydrochloride.

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GOLDIE, B. S., C. J. COATES, and R. BIRCH. "The Long Term Result of Digital Nerve Repair in No-Man’s Land." Journal of Hand Surgery 17, no. 1 (1992): 75–77. http://dx.doi.org/10.1016/0266-7681(92)90016-u.

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30 isolated lesions of digital nerves which had been repaired by microsurgical techniques were examined in 27 patients. The average length of follow-up was 25 months (range: 12–48 months). Patients were assessed subjectively using a visual analogue scale and examined for light touch, pain, two-point discrimination, electrical conductance and sensory threshold. Although 37% of fingers regained normal two-point discrimination, only 27% of patients graded their overall result as excellent and 40% complained of persistent hyperaesthesia for up to two years. None felt that their finger had regained normal sensation. All patients undergoing digital nerve repair should be warned that hyperaesthesia may persist for several years and that an adult will never regain normal sensation.

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Reichl, M., and M. J. Allen. "Hyperaesthesia associated with hyperextension injuries of the neck." Injury 18, no. 4 (1987): 234. http://dx.doi.org/10.1016/0020-1383(87)90003-9.

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Ruiz-Suarez, N., SFM Bhatti, M. Hermans, CB da Silva, and M. Hesta. "Food hypersensitivity and feline hyperaesthesia syndrome (FHS): A case report." Veterinární Medicína 66, No. 8 (2021): 363–67. http://dx.doi.org/10.17221/118/2020-vetmed.

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A 2-year-11-month-old female spayed cat was at the Small Animal Teaching Hospital of Ghent University presenting with hyperactivity, scratching and licking all over her body and an abnormal urination behaviour. Nothing remarkable was found on the dermatology and neurological examination. Based on the owner’s history and video material, the presence of feline hyperaesthesia syndrome (FHS) was hypothesised. A symptomatic treatment with gabapentin was established for a month without any significant improvement. An elimination diet with hydrolysed protein sources was started and, as a result, the dose of gabapentin was reduced after three days and completely stopped after one week. With the exception of two non-intentional exposures to non-hypoallergenic diets and the challenge with new protein sources by the owner, the cat has been free of symptoms, with the exception of a slight reaction in the lumbar area (significantly reduced in comparison before starting the diet), and without the use of medication. In conclusion, an elimination diet should be considered as part of the diagnostic plan for FHS and should not be delegated to the last step if the patient’s condition allows it.

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Tennant, Bryn. "Small animal Review." Companion Animal 25, no. 10 (2020): 1. http://dx.doi.org/10.12968/coan.2020.0087.

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Introduction: In this month's Small Animal Review we consider three recently published papers from other veterinary journals. The papers summarised focus on antimicrobials in reptiles, a novel polyneuropathy in huskies and clinical signs in dogs presenting with hyperaesthesia.

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FEARNSIDE, SM, AE KESSELL, and JR POWE. "Cervical hyperaesthesia in a Maltese Terrier with necrotising meningoencephalitis." Australian Veterinary Journal 82, no. 9 (2004): 550–52. http://dx.doi.org/10.1111/j.1751-0813.2004.tb11198.x.

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Tengtrisorn, Supaporn, Alan A. McNab, and James E. Elder. "Persistent infra-orbital nerve hyperaesthesia after blunt orbital trauma." Australian and New Zealand Journal of Ophthalmology 26, no. 3 (1998): 259–60. http://dx.doi.org/10.1111/j.1442-9071.1998.tb01323.x.

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De Strobel, F., V. Paluš, E. Vettorato, and G. B. Cherubini. "Cervical hyperaesthesia in dogs: an epidemiological retrospective study of 185 cases." Journal of Small Animal Practice 60, no. 7 (2019): 404–10. http://dx.doi.org/10.1111/jsap.12987.

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O'Leary, Dónal J. "A Swallowed Needle in a Cat Treated for Feline Hyperaesthesia Syndrome." Acupuncture in Medicine 33, no. 4 (2015): 336–37. http://dx.doi.org/10.1136/acupmed-2015-010807.

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Zabolotna, Iryna, Tatiana Bogdanova, Andrii Komlev, and Larysa Yurina. "CORRELATION OF CERVICAL TEETH INJURIES WITH DENTIN HYPERAESTHESIA IN YOUNG PEOPLE." Sworld-Us Conference proceedings, usc18-01 (May 30, 2023): 45–49. http://dx.doi.org/10.30888/2709-2267.2023-18-01-011.

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The study of indicators of dentine hyperesthesia in young people of Donetsk region, evaluation of their potential connection with cervical pathology of the teeth. Research methods. The clinical examination of 272 people aged 18-44 included a survey, coll

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Arendt-Nielsen, Lars, Robert Zachariae, and Peter Bjerring. "Quantitative evaluation of hypnotically suggested hyperaesthesia and analgesia by painful laser stimulation." Pain 42, no. 2 (1990): 243–51. http://dx.doi.org/10.1016/0304-3959(90)91168-i.

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Rodriguez, Alfonso, Elsa Beltran, Sandra Sanchis-Mora, and Carolina Palacios. "Bilateral laryngeal paralysis following a ventral slot surgery in a dog." Veterinary Record Case Reports 8, no. 2 (2020): e001109. http://dx.doi.org/10.1136/vetreccr-2020-001109.

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An English springer spaniel developed laryngeal paralysis immediately after a ventral slot decompression surgery to treat an intervertebral disc extrusion that was causing a C1–T2 myelopathy with cervical hyperaesthesia. Postsurgical stabilisation in the intensive care unit is described. This included mechanical ventilation, tracheostomy tube placement and care, and laryngeal tie-back surgery aftercare. Common complications after ventral slot decompression include pain, severe haemorrhage and deterioration in the neurological status. Laryngeal paralysis has not yet been reported in dogs after a ventral slot.

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Lim, Aymeric, C. K. Low, and P. K. Lee. "NECROSIS OF THE INDEX, MIDDLE AND RING FINGER PULPS AFTER TRANSFER OF A HETERODIGITAL NEUROVASCULAR ISLAND FLAP." Hand Surgery 03, no. 02 (1998): 307–10. http://dx.doi.org/10.1142/s0218810498000441.

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The heterodigital neurovascular island flap is indicated for the resurfacing of significant defects of the thumb pulp. It provides excellent soft tissue cover and sensibility.1 The complications reported have been mostly neurological and include poor sensation, hyperaesthesia, failure of cortical integration and cold intolerance.2–4 Loss of the flap from vascular insufficiency has also been reported.2,5 We report the loss of the index, middle and ring finger pulps in a patient after transfer of a heterodigital neurovascular island flap from the middle finger to the thumb.

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Rosenberg, William S., Brooke Swearingen, and Charles E. Poletti. "Contralateral Trigeminal Dysaesthesias Associated with Second Cervical Nerve Compression: A Case Report." Cephalalgia 10, no. 5 (1990): 259–62. http://dx.doi.org/10.1046/j.1468-2982.1990.1005259.x.

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This 70–year-old woman presented with a left C2 solitary metastatic lesion producing ipsilateral occipital pain associated with contralateral fronto-orbital dysaesthesias. Examination revealed analgesia in the left C2 dermatome and hyperaesthesia in the right forehead. These symptoms and findings resolved following a course of radiation therapy to the C2 metastasis. Ipsilateral trigeminal dysaesthesias produced by cervical lesions have been described, however, contralateral cervicogenic trigeminal dysaesthesias have not. Relevant experimental data are analysed; neural pathways are suggested by which a cervical lesion, especially at C2 or C3, may produce trigeminal dysaesthesias referred ipsilaterally or contralaterally.

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Bohnen, N., A. Twijnstra, J. Kroeze, and J. Jolles. "A Psychophysical Method for Assessing Visual and Acoustic Hyperesthesia in Patients with Mild Head Injury." British Journal of Psychiatry 159, no. 6 (1991): 860–63. http://dx.doi.org/10.1192/bjp.159.6.860.

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Although it is well known that patients with mild head injury (MHI) are less able to endure intense light and sound stimuli than normal people, there are few psychophysical studies that have objectively measured this type of hyperaesthesia. In the present study, using a computerised rating scale technique, both the maximal and submaximal levels of reduced tolerance to light and sound were assessed for a wide range of stimuli. Three to six days after the trauma, 40 MHI patients were significantly less tolerant to stimuli of intensities over 71 dB and 500 lux levels than controls. These intensities are common, and MHI patients may suffer as a consequence.

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Jukes, Alison, Marcus Gunew, and Rhett Marshall. "Severe muscle fasciculations and tremor in a cat with hypochloraemic metabolic alkalosis secondary to duodenal obstruction." Journal of Feline Medicine and Surgery Open Reports 3, no. 1 (2017): 205511691668642. http://dx.doi.org/10.1177/2055116916686427.

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Case summary An 18-month-old, female spayed, Australian Mist cat presented with a 24 h history of muscle tremors and inappetence progressing to collapse with generalised muscle fasciculations. The cat was diagnosed with a hypochloraemic metabolic alkalosis due to a duodenal foreign body found to be a trichobezoar at coeliotomy. The cat made a complete recovery after enterotomy to remove the trichobezoar, with cessation of neuromuscular clinical signs and normalisation of its electrolyte and acid–base imbalances. Relevance and novel information Muscle fasciculations and tremors in cats can be caused by intoxications, metabolic derangements, encephalomyelitis, feline hyperaesthesia syndrome and cerebellar diseases. The presenting clinical signs of severe muscle fasciculations and tremors have not previously been reported in association with an intestinal obstruction in the cat.

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Orgonikova, Ivona, Marco Rosati, Nicki Reed, Simon Tappin, and Viktor Palus. "Prolonged survival of a 7-year-old vizsla with histiocytic sarcoma affecting the spinal cord and protein-losing nephropathy after lomustine treatment." Veterinary Record Case Reports 8, no. 3 (2020): e000994. http://dx.doi.org/10.1136/vetreccr-2019-000994.

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A 7-year-old male entire vizsla, diagnosed with protein-losing nephropathy (PLN) one month previously, presented with lumbar hyperaesthesia. MRI of the lumbar spine revealed an extradural mass at the level of L3 vertebra. Most of the mass was surgically excised during left-sided pediculectomy at L3 and left-sided L2-L3 mini-hemilaminectomy. Histopathology revealed a moderately proliferative, lymphocyte/plasmacyte-rich, mesenchymo-invasive localised histiocytic sarcoma affecting the spinal cord. Chemotherapy with lomustine (1-(2-chloroethyl)-3-cyclohexyl-1-nitrosurea) was commenced for treatment of the histiocytic sarcoma and during therapy the persistent proteinuria resolved, having previously only shown an improvement with symptomatic treatment. The dog survived 881 days after diagnosis, which is exceptional in cases of histiocytic sarcomas affecting CNS.

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Martin, Sophie, Sara Shivapour, and Elsa Beltran. "Supracollicular fluid accumulation type 3 with concurrent hydrocephalus in a five-month-old crossbreed dog." Veterinary Record Case Reports 7, no. 2 (2019): e000800. http://dx.doi.org/10.1136/vetreccr-2018-000800.

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A five-month-old crossbreed dog was referred with a 36-hour history of cervical hyperaesthesia. CT and MRI of the head and neck identified supracollicular fluid accumulation type 3 with concurrent hydrocephalus, syringohydromyelia and cerebellar herniation. Medical treatment consisting of analgesia and mannitol was instigated, and once the patient was stabilised a supracollicular-peritoneal shunt system was placed. The patient initially responded very well to this treatment. Six days postoperatively, the patient sustained disconnection of the shunt system at the level of the pressure valve and distal shunt tubing. Revision surgery to repair the shunt was performed without further complication. The dog returned to being neurologically normal within four weeks. One year postoperatively, the patient remains neurologically normal with no further clinical signs nor shunt system complications.

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Bohnen, N., A. Twijnstra, G. Wijnen, and J. Jolles. "Recovery from visual and acoustic hyperaesthesia after mild head injury in relation to patterns of behavioural dysfunction." Journal of Neurology, Neurosurgery & Psychiatry 55, no. 3 (1992): 222–24. http://dx.doi.org/10.1136/jnnp.55.3.222.

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Parker, Roger. "‘Opera and …’: The Pleasures and Perils of Amalgamation." Cambridge Opera Journal 32, no. 2-3 (2020): 253–58. http://dx.doi.org/10.1017/s095458672100001x.

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We might start with the Index, often a good indicator of a book's flavour, its local habitation. First up is ‘Abbate, acoustics, acting, Adler, Adorno’, a reassuring miscellany; later on, the German-speaking collective of ‘Schopenhauer, Schreker, Schubart, Schumann-Heink’ awakens memories of time past. ‘Ventilation systems, Verdi, vitalism’, however, turns on the landing lights for a distinctly new approach, while ‘hygiene [both mental and moral], hyperacusis, hyperaesthesia acoustica, hypnosis, hysteria’ ushers in another region entirely: medicine, pathologies. Starting at the end, we are thus prepared: a sense of anticipation is allied to hopes of intriguing surprises in the offing. And such expectations are on the whole justified. In spite of its title – that fence-sitting conjunction – this collection is a worthy and serious attempt to write new chapters in musicology's revolving challenge to the internalist preoccupations of its past.

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Parr, Rebecca. "Targeted physiotherapy for pregnancy-related abdominal wall neuropathy." Journal of Pelvic, Obstetric and Gynaecological Physiotherapy 136, Spring (2025): 69–77. https://doi.org/10.62399/ncfk1831.

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Abdominal pain during pregnancy poses a diagnostic challenge because it has a wide range of potential causes. This case report explores the diagnosis and management of pregnancy-related abdominal wall neuropathy (PRAWN), an under-recognized condition characterized by nerve entrapment in the abdominal wall. The subject, who was experiencing chronic abdominal pain during pregnancy, exhibited PRAWN symptoms including a positive Carnett’s test, and site-specific pain and hyperaesthesia. Treatment with manual therapy, specific stretching techniques and patient education significantly reduced her symptoms. Numeric Pain Rating Scale scores decreased from 5/10 to 0/10, and the subject reported the complete resolution of her symptoms. This case highlights the importance of healthcare providers considering PRAWN in their differential diagnosis of pregnancy-related abdominal pain. It also suggests that physiotherapy may be a non-invasive management option for PRAWN, and further research is warranted.

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Selcer, R., W. H. Adams, W. B. Thomas, and B. E. Wilkens. "T9-T10 Intervertebral Disc Herniation in Three Dogs." Veterinary and Comparative Orthopaedics and Traumatology 09, no. 04 (1996): 177–78. http://dx.doi.org/10.1055/s-0038-1632526.

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SummaryThree middle-aged (6-8 years), intact male Dachshunds were admitted to the University of Tennessee Veterinary Teaching Hospital (UTVTH) with acute onset of back pain and pelvic limb paralysis.Physical examination of dog #1 revealed hyperaesthesia of the thoracolumbar spine. Superficial pain sensation was absent in the pelvic limbs, while deep pain sensation was intact. The cutaneous trunci (panniculus) reflex was absent caudal to the thoraco-lumbar region. Reflexes to the pelvic limbs were exaggerated.A myelogram showed dorsal deviation of the ventral contrast column and attenuation of the ventral and dorsal contrast columns at the T9-T10 disc space. A hemilaminectomy was performed from T9 to T10, and mineralized disc material was retrieved from the vertebral canal at T9-T10. The T9- T10 to L3-L4 disc spaces were fenestrated. Two weeks after surgery, superficial and deep pain sensation of the rearlimbs were present, but paralysis persisted. The animal was euthanatised at the owners’ request. A postmortem examination was not performed.Dog #2 displayed absent superficial pain sensation, and intact deep pain sensation of the pelvic limbs. Hyperaesthesia of the thoracolumbar region and hyperreflexia of the rear limbs were noted. Examination of the cutaneous trunci reflex was not performed. A myelogram revealed ventral extradural compression of the spinal cord at T9- T10. A T9-T10 hemilaminectomy revealed a large amount of extruded disc material, which was removed. The Tll- T12 to L4-L5 intervertebral discs were fenestrated. Forty-eight hours postoperatively, the patient regained voluntary motor function, and recovery was uneventful.Neurologic examination of dog #3 revealed absence of deep pain sensation in the pelvic limbs; duration of which was not known. Spinal radiographs and myelography revealed ventral extradural spinal cord compression at T9-T10 (Fig.). A right-sided hemilaminectomy at T9-T10 revealed a large amount of calcified disc material, ventral to the spinal cord. The T11-T12 through Ll- L2 intervertebral discs were fenestrated. Sixty days postoperatively, paralysis persisted and the dog was euthanatised. No postmortem examination was performed.Herniation of the T9-T10 intervertebral disc was diagnosed in three Dachshunds with acute paraplegia. The clinical diagnosis and surgical management of T9-T10 disc herniation are similar to that in the more common sites of disc herniation.

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Aragosa, Federica, Chiara Caterino, Giovanni Della Valle, et al. "Extradural Peripheral Nerve Sheath Tumour at T7 Level in a 2-Year-Old Dog." VCOT Open 04, no. 01 (2021): e41-e46. http://dx.doi.org/10.1055/s-0041-1731438.

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AbstractThe aim of this report is to describe an unusual localization of nerve sheath tumour (NST), clinical presentation, imaging, surgical management, and outcome in a 2-year-old dog. A 2-year-old female American Staffordshire Terrier presented with nonambulatory paraparesis, thoracolumbar hyperaesthesia, hindlimb hyperreflexia, and mild muscle atrophy. Computed tomography and magnetic resonance imaging revealed an extradural mass at T7-T8, without vertebral lesions. Surgical treatment consisted in resection of the soft tissue mass through dorsal laminectomy. The dog was ambulatory within 24 hours and free of recurrence at 18 months postoperatively. Histopathologic and features of immunohistochemistry were consistent with NST. The NST of this report was similar to those described before, but exhibited unusual characteristics, such as being extradural, without extension into intervertebral foramina, and being located in an atypical region (T7-T8). Moreover, survival time and relapse-free interval are greater than previously reported for similar cases.

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Bates, Nicola. "Tremorgenic mycotoxicosis in dogs." Companion Animal 27, no. 2 (2022): 1–6. http://dx.doi.org/10.12968/coan.2021.0049.

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Dogs commonly ingest tremorgenic mycotoxins because of their indiscriminate eating habits. Common sources are mouldy food, compost and rotten, fallen fruits and nuts. The mycotoxins penitrem A and roquefortine are produced by species of the mould Penicillium. Tremorgenic mycotoxicosis is characterised by rapid onset whole-body muscle tremors, vomiting, pyrexia, convulsions, ataxia, twitching and hyperaesthesia. Dogs are also at risk of aspiration. Treatment is aimed at decontamination and control of increased muscle activity and seizures to prevent complications from prolonged seizure activity. This will involve gut decontamination (depending on the condition of the dog), repeat doses of activated charcoal (as the mycotoxins undergo enterohepatic recirculation) and administration of sedatives, anticonvulsants and/or anaesthetics. Lipid emulsion should also be considered in severe cases. Prognosis is typically good in dogs with mild signs or controlled seizures, but more guarded where there is uncontrolled seizure activity or aspiration pneumonitis.

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ATHERTON, DUNCAN D., OMEED TAHERZADEH, DAVID ELLIOT, and PRAVEEN ANAND. "Age-Dependent Development Of Chronic Neuropathic Pain, Allodynia and Sensory Recovery after Upper Limb Nerve Injury in Children." Journal of Hand Surgery (European Volume) 33, no. 2 (2008): 186–91. http://dx.doi.org/10.1177/1753193408087029.

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Forty-nine children with distal upper limb nerve injury were studied at a mean follow-up of 2 years 3 months. Patients who were aged 5 years or younger at the time of nerve injury (15/49) had no chronic neuropathic pain symptoms or allodynia. Patients with allodynia on quantitative sensory testing but no spontaneous pain (8/49) were all older than 5 years and those reporting spontaneous chronic neuropathic pain (5/49) were all older than 12 years at the time of injury. Previous studies of adults with similar nerve injuries report chronic hyperaesthesia in up to 40% of cases. Semmes–Weinstein monofilament testing showed a positive correlation between age at injury and abnormal sensory threshold ( r = 0.60, P<0.0001). These findings indicate that young children show better sensory recovery and are less likely to develop long-term chronic neuropathic pain syndromes than adults following nerve injury.

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Jelinek, F. "Gliomatosis of the spinal cord in a cat: a case report." Veterinární Medicína 58, No. 6 (2013): 331–37. http://dx.doi.org/10.17221/6871-vetmed.

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Gliomatosis cerebri situated in the thoracolumbar and lumbosacral segments of the spinal cord was diagnosed in a Persian 10.5-year old tom cat. Clinical manifestation consisted of rump ataxy, weakened posture in the hind limbs, paraparesis, weakened spinal reflexes, no spinal hyperaesthesia or pain, and hypotonia of the urinary bladder. Magnetic resonance imaging revealed a diffuse hyperintense signal in the thoracolumbar junction and in lumbosacral segments (L6&ndash;S1) of the spinal cord. Normal size, form and colour of the spinal cord were apparent at autopsy; however, changes in grey matter shape were recorded on some transversal sections of the spinal cord. Dense, diffuse infiltration of the grey matter and surrounding white matter by glia-like neoplastic cells was histologically demonstrated. Immunohistochemical examination did not enable specification of the origin of the neoplastic cells but their neuroectodermal histogenesis can be assumed. On the basis of MRI, histological and immunohistochemical examinations gliomatosis of the spinal cord was diagnosed. &nbsp; &nbsp;

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Hamilton, Leonard, Colin Driver, Anna Tauro, Gary Campbell, and Noel Fitzpatrick. "Mineralization of the transverse ligament of the atlas causing compressive radiculopathy." Veterinary and Comparative Orthopaedics and Traumatology 29, no. 03 (2016): 253–58. http://dx.doi.org/10.3415/vcot-15-09-0161.

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Summary Objective: To describe a case of a Boxer dog with radiculopathy due to mineralization of the transverse ligament of the atlas and subsequent resorption and resolution of clinical signs after atlantoaxial arthrodesis and odontoidectomy. Case Report: A five-year-old neutered female Boxer dog was presented with a four-month history of cervical hyperaesthesia refractory to medical management. Neurological examination and magnetic resonance imaging indicated a diagnosis of radiculopathy due to cervical nerve root impingement by dystrophic mineralization of the transverse ligament of the atlas. Odontoidectomy was performed by a ventral approach and atlantoaxial arthrodesis was achieved with a ventral composite polymethylmethacrylate and pin fixation. Results: Atlantoaxial arthrodesis and progressive resorption of the mineralization following stabilization facilitated indirect decompression. The radioclinical diagnosis and response to arthrodesis was considered ana -logous to retro-odontoid pannus in the human. Clinical relevance: A clinical condition similar to retro-odontoid pannus may exist in the canine and may be amenable to atlantoaxial arthrodesis.

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Bruckner, F. E., S. A. Allard, and N. A. Moussa. "Benign Thoracic Pain." Journal of the Royal Society of Medicine 80, no. 5 (1987): 286–89. http://dx.doi.org/10.1177/014107688708000509.

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Seventy-three patients with mid-dorsal and/or unilateral chest pain seen consecutively in the rheumatology clinic by a single clinician over a three-year period were studied, after exclusion of visceral disease. The majority were young women. The pain was dull and continuous, was aggravated by coughing and sneezing and relieved by rest. There was frequently tenderness over the thoracic spine (T4–5) and an adjacent rib, and pain at extremes of thoracic spinal movement in one or two directions was invariable. Cutaneous hyperaesthesia in a radicular distribution was found in 16.4%, but there were no other neurological abnormalities. This clinical picture is probably the result of a thoracic disc prolapse, though confirmation by myelography was not thought to be ethically justified. The condition settled in most of the patients following manipulative treatment and advice on back care. No patient developed spinal cord compression. It is concluded that this is a common benign condition which deserves wider recognition.

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Matsutomo, R., K. Takebayashi, and Y. Aso. "Assessment of Peripheral Neuropathy Using Measurement of the Current Perception Threshold with the Neurometer® in Patients with Type 2 Diabetes Mellitus." Journal of International Medical Research 33, no. 4 (2005): 442–53. http://dx.doi.org/10.1177/147323000503300410.

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Measurement of current perception threshold (CPT) using the Neurometer® at 2000, 250 and 5 Hz assesses function in three different nerve fibre types. This method was used to investigate peripheral neuropathy in 116 patients with type 2 diabetes mellitus and 38 healthy controls. The CPT at 2000 Hz was significantly higher in diabetic patients than in controls, and showed a significant negative correlation with motor and sensory nerve conduction velocities. At 250 Hz, CPT showed a significant positive correlation with the vibration perception threshold. At 5 Hz, the change in systolic blood pressure in the Schellong test in patients with hypoaesthesia tended to be less than in those with normal sensation or hyperaesthesia. Significantly higher CPT values were obtained in patients with proliferative diabetic retinopathy and macroalbuminuria. These data suggest that CPT is useful in detecting abnormalities of myelinated as opposed to unmyelinated nerve fibres in patients with type 2 diabetes.

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Hall, Georgina, Craig Breheny, Zohra Khan, Tobias Schwarz, and Richard J. Mellanby. "Severe nutritional deficiencies and osteopenia in a dog fed a homemade raw diet." Veterinary Record Case Reports 8, no. 1 (2020): e001038. http://dx.doi.org/10.1136/vetreccr-2019-001038.

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A seven-month-old male entire Bulldog presented for a three-week history of progressive lethargy, exercise intolerance, hindlimb paresis, muscle atrophy and hyperaesthesia. The dog had initially been raised on the bitch’s milk before maternal illness resulted in him transitioning onto milk replacer. He was weaned onto commercial puppy food until four months of age before being transitioned onto a homecooked diet. This diet comprised of raw meat, collected weekly from a local abattoir, homecooked cereals and vegetables. The patient was oxygen-dependent on presentation, requiring 40 per cent inspired oxygen concentration to maintain normoxaemia. Investigations revealed marked osteopenia with concurrent severe hypovitaminosis D, hypocalcaemia and hyperparathyroidism; hypovitaminosis A; hypothyroidism and concurrent severe pneumonia. Despite intensive medical care, nutritional interventions and escalating oxygen therapy, the dog was euthanased due to a deterioration in respiratory function. This case report highlights the severe clinical complications associated with the consumption of a nutritionally incomplete diet.

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Göransson, Ingrid, and Ragnhild Cederlund. "A study of the effect of desensitization on hyperaesthesia in the hand and upper extremity after injury or surgery." Hand Therapy 16, no. 1 (2010): 12–18. http://dx.doi.org/10.1258/ht.2010.010023.

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SOOD, M. K., and D. ELLIOT. "Treatment of Painful Neuromas of the Hand and Wrist by Relocation into the Pronator Quadratus Muscle." Journal of Hand Surgery 23, no. 2 (1998): 214–19. http://dx.doi.org/10.1016/s0266-7681(98)80177-0.

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Thirteen painful end-neuromas of nerves of the palm and the dorsum of the hand were treated by resection of the neuroma and relocation of the nerve ends into the pronator quadratus muscle proximal to the wrist in ten patients. The effectiveness of this treatment was assessed by measurement of changes in level of spontaneous pain, pain on pressure, pain on movement and hyperaesthesia at the original site and at the site to which the nerve was relocated. Subjective comments on changes of hand function and ability to return to work were also recorded. All ten patients reported total relief or marked improvement in each of the four modalities of pain assessed. In the five patients in whom the neuromas were the only significant cause of hand dysf.unction, there was sufficient improvement in hand function to allow the patients to return to work. In this series, the pronator quardratus muscle has proved a suitable site for relocation of sensory nerve ends after resection of painful neuromas in the proximal part of the hand and wrist.

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DHAR, S., I. C. M. GRAY, W. A. JONES, and F. H. BEDDOW. "Simple Excision of the Trapezium for Osteoarthritis of the Carpometacarpal Joint of the Thumb." Journal of Hand Surgery 19, no. 4 (1994): 485–88. http://dx.doi.org/10.1016/0266-7681(94)90214-3.

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We have reviewed the results in 34 patients (39 operations) following simple excision of the trapezium for osteoarthritis of the basal joint of the thumb. The average age at operation was 57 years and the average follow-up was 6 years. All the patients were graded clinically and radiologically and were asked their opinion of the procedure. There was dramatic relief of pain following this procedure. Stability of the thumb was not compromised. When compared to the unoperated side, thumb length, thumb abduction and first web span were similar. There was a reduction in pinch strength (operated 8.1 k.p.a., non-operated 9.6 k.p.a.) and grip strength (operated 15.5 k.p.a., non-operated 19.5 k.p.a.) and an increase in MP extension (operated 5.4°, non-operated 2.9°) following this procedure but the differences were not statistically significant. 11 patients (32%) had scar hyperaesthesia on testing but this was a clinical problem in two patients only (5%). Simple excision of the trapezium is a satisfactory procedure for the majority of patients with this disorder, but has a long post-operative rehabilitation period.

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Borsari, Andrea. "Georg Simmel und die Ästhetische Theorie der Architektur." Simmel Studies 28, no. 1 (2024): 9–42. https://doi.org/10.7202/1115153ar.

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The article is dedicated to the reconstruction and recapitulation of Georg Simmel's relationship to architecture and to the aesthetics of the field of architecture. To this aim, a number of texts have been identified and discussed in Simmel's production that describe the urban dimension, as dimension of the city and of architecture as a modality of the construction of buildings, objects and places to inhabit the world and thus give it a certain configuration. From this discussion derives the plural field of oppositions in relation to the urban-architectural dimension, according to a view of Simmelian thought based on a kind of law of contrast, which can be exemplified in the following set of “oppositional pairs” found in Simmel's work: nature and culture (§ 2), hyperaesthesia and anaesthesia (§ 3), aesthetic “superadditum” and abstraction (§ 4), artistic will and practical functionality (§ 5), connecting and separating (§ 6), transience and eternity or, in architectural terms, temporary and solidity (§ 7), freedom and solitude - subjective culture and objective culture (§ 8). The paper proposes an attempt to trace this series of contrasts and to conclude with an initial assessment of the path traveled and some reflections on a possible convergence between aesthetic and social morphology (§ 9).

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Kubata, Bruno Kilunga, Michael Duszenko, Zakayi Kabututu та ін. "Identification of a Novel Prostaglandin F2α Synthase in Trypanosoma brucei". Journal of Experimental Medicine 192, № 9 (2000): 1327–38. http://dx.doi.org/10.1084/jem.192.9.1327.

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Members of the genus Trypanosoma cause African trypanosomiasis in humans and animals in Africa. Infection of mammals by African trypanosomes is characterized by an upregulation of prostaglandin (PG) production in the plasma and cerebrospinal fluid. These metabolites of arachidonic acid (AA) may, in part, be responsible for symptoms such as fever, headache, immunosuppression, deep muscle hyperaesthesia, miscarriage, ovarian dysfunction, sleepiness, and other symptoms observed in patients with chronic African trypanosomiasis. Here, we show that the protozoan parasite T. brucei is involved in PG production and that it produces PGs enzymatically from AA and its metabolite, PGH2. Among all PGs synthesized, PGF2α was the major prostanoid produced by trypanosome lysates. We have purified a novel T. brucei PGF2α synthase (TbPGFS) and cloned its cDNA. Phylogenetic analysis and molecular properties revealed that TbPGFS is completely distinct from mammalian PGF synthases. We also found that TbPGFS mRNA expression and TbPGFS activity were high in the early logarithmic growth phase and low during the stationary phase. The characterization of TbPGFS and its gene in T. brucei provides a basis for the molecular analysis of the role of parasite-derived PGF2α in the physiology of the parasite and the pathogenesis of African trypanosomiasis.

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Kaka, Ubedullah, Hui Cheng Chen, Yong Meng Goh, Adamu Abdul Abubakar, Sharida Fakurazi, and Mahdi Ebrahimi. "Validation of a Modified Algometer to Measure Mechanical Nociceptive Thresholds in Awake Dogs." BioMed Research International 2015 (2015): 1–7. http://dx.doi.org/10.1155/2015/375421.

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This study was conducted to validate the use of a modified algometer device to measure mechanical nociceptive thresholds in six dogs. Dogs were administered morphine intravenously (IV) at 1 mg/kg or saline at equivolume in a crossover design with one-week washout period. Mechanical nociceptive thresholds were determined before, after the administration of treatments at 5 minutes, and hourly for 8 hours. Thresholds were recorded at the carpal pad, metacarpal foot pad, tibia, femur, and abdomen. Heart rates, body temperature, and respiration were recorded at similar time points. Thresholds increased significantly (P<0.05) from baseline values for up to 3 hours at tibia and abdomen, 4 hours at metacarpal pad, and 5 hours at the carpal pad and femur. Hypothermia, bradycardia, and change in respiration were observed in all dogs after morphine injection. Saline did not alter any threshold levels during the eight-hour study period, indicating no evidence of tolerance, learned avoidance, or local hyperaesthesia. The device and methods of testing were well tolerated by all the dogs. Results suggest that the modified algometer and method of application are useful to measure nociceptive mechanical thresholds in awake dogs.

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Dorothy, Joe, Boyle Thomas, Roy Amit, Leschziner Guy, and Evans Matthew. "THUR 132 Neuroschistosomiasis: complication of a neglected tropical disease." Journal of Neurology, Neurosurgery & Psychiatry 89, no. 10 (2018): A15.2—A15. http://dx.doi.org/10.1136/jnnp-2018-abn.55.

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Neuroschistosomiasis is an under-recognised complication of one of the world’s most prevalent, yet neglected parasitic diseases, which if left untreated can result in severe disability. Although schistosomiasis is most commonly found in the tropics, neurologists in developed countries must have a low index of suspicion in the appropriate clinical setting.We describe a 17 year old previously fit and well Guinean lady presenting with subacute, progressive, symmetric lower limb hyperaesthesia and urinary retention. Neurological examination was consistent with a myeloradiculopathy. Initial tests revealed an eosinophilia and raised ESR. CSF and imaging findings supported the clinical diagnosis of myeloradiculopathy secondary to schistosomiasis. She responded well to empirical steroids and praziquantel with complete resolution of sensory and urinary symptoms over several weeks. Serology later confirmed the diagnosis.Transverse myelitis and myeloradiculopathy affecting the conus medullaris and/or cauda equina are the most common presentations associated with neuroschistosomiasis. Symptoms are principally due to an inflammatory response to the retained schistosome eggs. This case details the differential diagnosis of a subacute myeloradiculopathy and highlights the importance of a thorough travel history. In the appropriate clinical context, neuroschistosomiasis should be included in the differential diagnosis of a subacute myeloradiculopathy, enabling prompt diagnosis and optimal management.

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Amengual Batle, Pablo, Clare Rusbridge, Tim Nuttall, Sarah Heath, and Katia Marioni-Henry. "Feline hyperaesthesia syndrome with self-trauma to the tail: retrospective study of seven cases and proposal for an integrated multidisciplinary diagnostic approach." Journal of Feline Medicine and Surgery 21, no. 2 (2018): 178–85. http://dx.doi.org/10.1177/1098612x18764246.

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Case series summary This was a retrospective study on the clinical features and response to treatment in seven cats with feline hyperaesthesia syndrome (FHS) and tail mutilation. FHS is a poorly understood disorder characterised by skin rippling over the dorsal lumbar area, episodes of jumping and running, excessive vocalisation, and tail chasing and self-trauma. The majority of the cats were young, with a median age of 1 year at the onset of clinical signs, male (n = 6) and with access to the outdoors (n = 5). Multiple daily episodes of tail chasing and self-trauma were reported in five cats, with tail mutilation in four cats. Vocalisation during the episodes (n = 5) and rippling of lumbar skin (n = 5) were also reported. Haematology, serum biochemistry, Toxoplasma gondii and feline immunodeficiency virus/feline leukaemia virus serology, MRI scans of brain, spinal cord and cauda equina, cerebrospinal fluid analysis and electrodiagnostic tests did not reveal any clinically significant abnormalities. A definitive final diagnosis was not reached in any of the cats, but hypersensitivity dermatitis was suspected in two cases. A variety of medications was used alone or in combination, including gabapentin (n = 6), meloxicam (n = 4), antibiotics (n = 4), phenobarbital (n = 2), prednisolone (n = 2) and topiramate (n = 2); ciclosporin, clomipramine, fluoxetine, amitriptyline and tramadol were used in one cat each. Clinical improvement was achieved in six cases; in five cats complete remission of clinical signs was achieved with gabapentin alone (n = 2), a combination of gabapentin/ciclosporin/amitriptyline (n = 1), gabapentin/prednisolone/phenobarbital (n = 1) or gabapentin/topiramate/meloxicam (n = 1). Relevance and novel information This is the first retrospective study on a series of cats with FHS. The diagnostic work-up did not reveal any significant abnormalities of the central or peripheral nervous system; dermatological and behavioural problems could not be ruled out. We propose an integrated multidisciplinary diagnostic pathway to be used for the management of clinical cases and for future prospective studies.

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Ntsiea, Veronica. "The prevalence and management of central post-stroke pain at a hospital in Zimbabwe." Malawi Medical Journal 32, no. 3 (2020): 132–38. http://dx.doi.org/10.4314/mmj.v32i3.5.

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BackgroundCentral post-stroke pain (CPSP) is a poorly diagnosed chronic pain. It is under-treated and usually mismanaged. ObjectiveTo establish the prevalence of CPSP and its management in stroke clinics at a tertiary hospital.MethodsThis was a cross-sectional design with stroke patients and health professionals from the stroke clinic at the tertiary hospital in Zimbabwe. ResultsOut of 166 stroke survivors, 8% had CPSP. Younger age (<60 years) was significantly associated with CPSP (P<0.003). Pain characteristics of CPSP were hyperaesthesia (10, 71%), electric shocks (9, 64%), temperature allodynia (9, 64%) and allodynia (12, 86%). Ten health professionals participated in the study: one (10%) reported using Douleur Neuropathique 4 (to diagnose neuropathic pain) and two (20%) reported using sensory tests. Four patients (44%) were on paracetamol (acetaminophen) and on weak opiates such as codeine. None of the patients were on anticonvulsants or antidepressants. Two medical doctors (50%) used weak opiates as second-line management. Five patients (36%) reported receiving a combination of massage, stretching, general exercise and moist heat or cryotherapy. ConclusionThe prevalence of CPSP in the study group is within international range. There is a need for appropriate management and use of tests and outcome measures for diagnosis of CPSP.

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