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Journal articles on the topic 'ICT as a tutor'

Author: Grafiati

Published: 4 June 2021

Last updated: 7 February 2022

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1

Сисоєва, Світлана Олександрівна, and Катерина Петрівна Осадча. "FORMATION OF THE TUTOR ICT-COMPETENCE IN THE PROCESS OF FUTURE TEACHERS’ PROFESSIONAL TRAINING." Information Technologies and Learning Tools 80, no. 6 (2020): 207–21. http://dx.doi.org/10.33407/itlt.v80i6.4182.

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The widespread proliferation of information and communication technologies and the task of meeting the sustainable development goals by overcoming the uneven access of the younger generation to information and communication technologies require the presence of the high level of the ICT competence and the ability to carry out tutoring activities in the information society for teachers-to-be. The paper offers the methodological approaches (contents, methods, tools, and technologies) of forming the tutor ICT competence in the process of future teachers’ professional training. The educational cont

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Muyaka, Jafred, and Peter Mugo Gathara. "Tutor ICT Skills and the Realisation of Kenya’s Vision 2030." Msingi Journal 1, no. 1 (2018): 317–49. http://dx.doi.org/10.33886/mj.v1i1.60.

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The Kenya Vision 2030 identifies science, technology and innovation as key drivers in creating wealth, social welfare and international competitiveness. In recognition of the role of technology in achieving Vision 2030, the government pledged to strengthen technical capabilities by emphasising technological learning at all levels. The vision affirmed that it is only through an educated and skilled manpower that Kenya will be able to create, share and utilise knowledge well. To produce a workforce capable of fitting into the knowledge driven society, training of teachers in Primary Teachers Col

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Murofushi, Keiko Nemoto, Nozomi Kitamura, Yasuo Yoshioka, et al. "A Clinical Evaluation of American Brachytherapy Society Consensus Guideline for Bulky Vaginal Mass in Gynecological Cancer." International Journal of Gynecologic Cancer 28, no. 7 (2018): 1438–45. http://dx.doi.org/10.1097/igc.0000000000001305.

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ObjectivesAmerican Brachytherapy Society (ABS)-recommended interstitial brachytherapy (IBT) should be considered for bulky vaginal tumor thicker than 5 mm. The aim of this study was to evaluate the ABS consensus guideline for patients with severe vaginal invasion based on our long-term follow-up results.Methods/MaterialsThe study included 7 patients with vaginal cancer and 14 patients with cervical cancer invading to the lower vagina. Based on prebrachytherapy magnetic resonance imaging findings, patients received intracavitary brachytherapy (ICT) for vaginal tumors 5 mm or less or IBT for vag

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Podpliota, Svitlana. "Tutoring Support as an Important Component of the Educational Process in the Context of the Development of Information and Communication Technology." Ukrainian Journal of Educational Studies and Information Technology 5, no. 3 (2017): 84–91. http://dx.doi.org/10.32919/uesit.2017.03.08.

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There are a lot of significant structural changes in almost all higher educational institutions in Ukraine due to time requirements. Accession to a single European space, new educational standards requires the revision and expansion of the content of pedagogical activities, functions and roles implemented by educators. Students are granted the rights and opportunities for the most complete satisfaction of individual educational requests. There was a need to review the ideas about the content of teaching activities and the emergence of new positions. In recent years, scientists have been active

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Basso-Aránguiz, Matilde, Mario Bravo-Molina, Antonella Castro-Riquelme, and César Moraga-Contreras. "Propuesta de modelo tecnológico para Flipped Classroom (T-FliC) en educación superior." Revista Electrónica Educare 22, no. 2 (2018): 1. http://dx.doi.org/10.15359/ree.22-2.2.

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The Technology Model, called T-FliC is proposed for Flipped Classroom. The aim is to provide IT facilities to the aforementioned pedagogical model. This proposal may be implemented at different levels of higher education. T-FliC is primarily based on the use of free technology resources, especially Google applications such as Classroom, Drive, and YouTube, because they are widely used by students and teachers. This extensive use permits to replicate this model in different educational contexts. The T-FliC model incorporates five ICT phases, ranging from the planning of teaching-learning activi

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Osadcha, Kateryna P. "ТЬЮТОРСЬКИЙ СУПРОВІД НАВЧАННЯ МАТЕМАТИКИ ЗАСОБАМИ ІНФОРМАЦІЙНО-КОМУНІКАЦІЙНИХ ТЕХНОЛОГІЙ". Information Technologies and Learning Tools 61, № 5 (2017): 36. http://dx.doi.org/10.33407/itlt.v61i5.1693.

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The paper describes the tutor activity in the process of mathematics teaching support on the basis of the use of information and communication technologies (ICT). The author has analysed the available Internet resources and mobile applications in mathematics, which are classified according to their functional purposes into groups: systems of mass open courses, platforms for adaptive learning, video channels, mathematical online simulators, online tasks, mathematical games, mathematical portals, online platforms, mathematical sites, mathematical online platforms, mathematical services, mobile a

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Vasilenko, Timofey Andreevich. "The Use of Information and Communication Technologies in Teaching Economics to Students in Basic School." Development of education, no. 3 (9) (September 24, 2020): 84–88. http://dx.doi.org/10.31483/r-86210.

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The author of the article outlines that the problem of teaching methods is one of the most important in pedagogical science and practice of school teaching, since teaching methods are the main tools with which a tutor teaches the basics of science to students, develops their cognitive abilities, ensures personal development and forms a scientific worldview. The article formulates the role of information and communication technologies (ICT) in the educational process. The pedagogical experiment of using ICT in teaching economics to primary school children is described. The purpose of the resear

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Suartini, Tuti Suartini. "- DEVELOPMENT OF MODEL BLENDED LEARNING IN COOPERATIVE LEARNING FOR TECHNOLOGY AND ENGINEERING SKILLS IN VOCATIONAL EDUCATION." Asia Proceedings of Social Sciences 5, no. 1 (2019): 11–18. http://dx.doi.org/10.31580/apss.v5i1.1068.

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Increasing the interest and willingness of students to learn a material was determined from the behavior of students in used information communication technology. The learning model developed was a cooperative learning model based on Blended Learnng. Utilization of information technology, by not leaving the pattern of direct guidance from instructors and the used of learning resources to improve literacy mastery of abilities in technology and engineering became important. The Research and Development (R&D) procedure used Blended learning cooperative learning model design in the form of onl

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Chikileva, Lyudmila S. "The Role of the Tutor in the Choice of Pedagogical Management Tools for Autonomous Work in Foreign Languages." Integration of Education 23, no. 3 (2019): 475–89. http://dx.doi.org/10.15507/1991-9468.096.023.201903.475-489.

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Introduction. The paper presents the results a study of the implementation of individual educational routes in students’ autonomous foreign language study at a non-linguistic university. Factors determining student motivation and satisfaction with the autonomous study using the Rosetta Stone Advantage platform were considered. The purpose of the study was to find out how tutors manage autonomous work and what ICT tools are used in this process. The relevance of this study is determined by the importance of the implementation of electronic platforms in the process of teaching foreign languages,

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Mutanana, Ngonidzashe. "Open and Distance Learning in Rural Communities of Zimbabwe: Exploring Challenges Faced by Zimbabwe Open University Students in Kadoma District, Zimbabwe." Asian Journal of Humanity, Art and Literature 6, no. 1 (2019): 49–58. http://dx.doi.org/10.18034/ajhal.v6i1.349.

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This study sought to explore challenges faced by Open and Distance Learning (ODL) students in rural communities using Kadoma District as a case study. The specific objectives of this study were to (i) identify challenges faced by ODL students in rural communities in achieving their educational goals and (ii) establish effects of these challenges in accomplishing/finalizing their programmes. The research employed a mixed research approach to triangulate the results. The study used a case study research design to solicit information. The target population was undergraduate students who were curr

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Blando, Jorge, Anu Sharma, Maria Gisela Higa, et al. "Comparison of immune infiltrates in melanoma and pancreatic cancer highlights VISTA as a potential target in pancreatic cancer." Proceedings of the National Academy of Sciences 116, no. 5 (2019): 1692–97. http://dx.doi.org/10.1073/pnas.1811067116.

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Immune checkpoint therapy (ICT) has transformed cancer treatment in recent years; however, treatment response is not uniform across tumor types. The tumor immune microenvironment plays a critical role in determining response to ICT; therefore, understanding the differential immune infiltration between ICT-sensitive and ICT-resistant tumor types will help to develop effective treatment strategies. We performed a comprehensive analysis of the immune tumor microenvironment of an ICT-sensitive tumor (melanoma, n = 44) and an ICT-resistant tumor (pancreatic cancer, n = 67). We found that a pancreat

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Brudermann, Cédric. "From action research to the implementation of ICT pedagogical tools: taking into account students’ needs to propose adjusted online tutorial practice." ReCALL 22, no. 2 (2010): 172–90. http://dx.doi.org/10.1017/s0958344010000066.

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AbstractThis paper deals with the implementation of an “online pedagogical assistant” in a blended learning device for English for Special Purposes (ESP) students in a French university (UPMC, Paris VI). As it is now, it comprises a customized website designed to serve as a guide through the development of the students’ work.The architecture of this website and the way it is meant to be used are parameters derived from the conclusions of action research carried out in 2007–2008 in another French university (Perpignan) amongst B1/B2 ESP students.1 The perspective of that study was to examine th

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Rudžianskas, Viktoras, Erika Korobeinikova, Milda Rudžianskienė, et al. "Use of 18F-FDG PET/CT Imaging for Radiotherapy Target Volume Delineation after Induction Chemotherapy and for Prognosis of Locally Advanced Squamous Cell Carcinoma of the Head and Neck." Medicina 54, no. 6 (2018): 107. http://dx.doi.org/10.3390/medicina54060107.

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Background and objectives: Induction chemotherapy (ICT) before definitive chemoradiation (CRT) gives high response rates in locally advanced squamous cell carcinoma of the head and neck (LA-SCCHN). However, pre-ICT gross tumor volume (GTV) for radiotherapy (RT) planning is still recommended. As 18F-FDG PET/CT has an advantage of biological tumor information comparing to standard imaging methods, we aimed to evaluate the feasibility of 18F-FDG PET/CT-based post-ICT GTV delineation for RT planning in LA-SCCHN and to assess the prognostic value of PET parameters: maximum standardized uptake value

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Shkolnyi, O., and Yu Tykhonenko. "ADVISABILITY AND POSSIBILITY OF USING ICT DURING PREPARATION FOR THE EIA IN MATHEMATICS." Physical and Mathematical Education 28, no. 2 (2021): 11–16. http://dx.doi.org/10.31110/2413-1571-2021-028-2-002.

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Formulation of the problem. At present, any researches on the methodology of organizing and conducting external independent assessment of academic achievements in mathematics of Ukrainian graduates has become extremely relevant. In particular, this is due to the fact that from 2021 the EIA in mathematics is mandatory in the system of state final attestation. The aim of this work is to determine the advisability and possibility of using information and communication technologies in preparation for the EIA in mathematics. To achieve this goal, we organized a statistical survey of students, the r

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Swamy S, Dr Kendaganna, Shaila H Kopal, Sushmitha N, Shruthi P, and Dr Uma B V. "An Effective Practice of ICT Tools in Higher Education to Improve the Teaching Learning Process." Journal of University of Shanghai for Science and Technology 23, no. 06 (2021): 940–60. http://dx.doi.org/10.51201/jusst/21/05368.

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Education is a process that simplifies learning. It should be a continuous process in one’s life to attain success. Over the decades, Information and Communication Technologies (ICT) have gradually begun to play a very important role in education, with their usage in education is growing worldwide continuously. These methods allow access to information through the internet. In education, ICT is the method of teaching that uses information and communication technology to support, improve and optimize the transfer of information, in turn leading to the invention of smart education. This improves

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Goswami, Sangeeta, Yulong Chen, Swetha Anandhan, et al. "ARID1A mutation plus CXCL13 expression act as combinatorial biomarkers to predict responses to immune checkpoint therapy in mUCC." Science Translational Medicine 12, no. 548 (2020): eabc4220. http://dx.doi.org/10.1126/scitranslmed.abc4220.

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Immune checkpoint therapy (ICT) can produce durable antitumor responses in metastatic urothelial carcinoma (mUCC); however, the responses are not universal. Despite multiple approvals of ICT in mUCC, we lack predictive biomarkers to guide patient selection. The identification of biomarkers may require interrogation of both the tumor mutational status and the immune microenvironment. Through multi-platform immuno-genomic analyses of baseline tumor tissues, we identified the mutation of AT-rich interactive domain-containing protein 1A (ARID1A) in tumor cells and expression of immune cytokine CXC

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Igboeli Uchenna H. and Bisallah Hashim I. "ICT Infrastructural and Technical Challenges: A Major Impediment towards the Development of Open and Distance Learning (ODL) in Nigeria." International Journal of Distance Education and E-Learning 6, no. 1 (2021): 1–17. http://dx.doi.org/10.36261/ijdeel.v6i1.1419.

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In the fast-growing population of Africa, Nigeria has become the most populous nation with over 177,000,000 inhabitants and consisting of about 32% youths (Abdulrahman et al, 2014). Sustainable development can only be achieved through proper education at all levels. While the regular classroom-based educational programmes have been characterized by incessant strikes and ever-increasing requests for admission due to increasing population, the introduction and acceptance of Open and Distance Learning programmes (ODL) as an alternative to classroom based system, has become imperative to cater for

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Frankel, Arthur E., Kenya Honda, Bruce Roberts, et al. "Precision probiotic therapy enhances immune checkpoint therapy efficacy in melanoma bearing mice." Journal of Clinical Oncology 37, no. 15_suppl (2019): e14195-e14195. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.e14195.

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e14195 Background: Immune checkpoint inhibitor therapy, ICT, achieves remissions in melanoma patients but factors modulating response are not well defined. Our group (Frankel et al. Neoplasia 2017) and others have identified specific gut microbiota associated with improved ICT response. Recently, we identified specific gut microbiota that induce adaptive immune responses and potentiate ICT (Tanoue et al. Nature 2019). In this study, we determined whether this predefined consortia of gut microbiota augment ICT efficacy in melanoma bearing mice. Methods: Mice (C57BL/6, 6-8wk old, female, Jackson

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Šedienė, Severina, Ilona Kulakienė, Viktoras Rudžianskas, and Rita Ambrazienė. "The Role of 18-Fluoro-2-Deoxy-Glucose Positron Emission Tomography/Computed Tomography as Response and Prognosis Predictive Factor of Concurrent Chemoradiotherapy after Induction Chemotherapy in Head and Neck Squamous Cell Carcinoma: A Prospective Study." Medicina 54, no. 2 (2018): 31. http://dx.doi.org/10.3390/medicina54020031.

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Background and objectives: The importance of induction chemotherapy (ICT) followed by concurrent chemoradiotherapy (CCRT) has been re-established in recent years aiming at fewer metastatic sites and better control of the disease. We prospectively studied the possibility of early prediction of overall survival (OS) and progression-free survival (PFS) after 3 cycles of chemotherapy with doxetacel, cisplatin and 5-fluorouracil using 18-fluoro-2-deoxy-glucose positron emission tomography computed tomography (18F-FDG PET/CT) in patients with head and neck squamous cell cancer. To our knowledge, thi

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Bagshaw, Mike. "Reflections on a Socratic approach to engagement." Industrial and Commercial Training 46, no. 7 (2014): 357–63. http://dx.doi.org/10.1108/ict-04-2014-0025.

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Purpose – The purpose of this paper is to enhance involvement in the learning process in order that students are active co-creators in their learning, developing their capability for proactive change. Design/methodology/approach – Action inquiry (Torbert, 2004). This involves simultaneously conducting action and inquiry in a systematic way. Findings – Engagement is a “contact sport” in which complex problems can only be solved by the development of social collaboration where the authors are able to share knowledge and assumptions and co-create together. This requires that groups go through a d

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Gusango, Emmanuel, John Maani, and John Ssetumba. "ICT and Reflective Practice integration; A Constructivists Approach in Teacher Preparation at Primary Teachers Colleges in South Eastern Uganda." American Journal of Education and Practice 5, no. 1 (2021): 37–52. http://dx.doi.org/10.47672/ajep.704.

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Purpose: The purpose of this study was to explore the ICT and reflective practice integration in teacher preparation at Primary Teachers Colleges and to establish whether these practices were among the constructivist approaches being used to teach students. Methodology: This phenomenological study explored the lived experiences of tutors and students in light of constructivists’ teaching. It involved 3 PTCs and 15 participants who were purposively sampled. This study used a qualitative research design. Data was gathered using in-depth multiple interviews and analyzed following Moustakas

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Rudnick, Jeremy David, Karen L. Fink, Joseph C. Landolfi, et al. "Immunological targeting of CD133 in recurrent glioblastoma: A multi-center phase I translational and clinical study of autologous CD133 dendritic cell immunotherapy." Journal of Clinical Oncology 35, no. 15_suppl (2017): 2059. http://dx.doi.org/10.1200/jco.2017.35.15_suppl.2059.

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2059 Background: A hallmark of glioblastoma is the high incidence of tumor recurrence, thought to be triggered by cancer stem cells. These tumorigenic cells are resistant to irradiation and chemotherapeutic agents. The target antigen, CD-133, was chosen because it has been reported as a cancer stem cell antigen overexpressed in glioblastoma tumors and associated with shorter survival. Recent clinical trials suggest that the mean overall survival for these patients is roughly 5-9 months, emphasizing the important unmet medical need in this disease requiring additional strategic approaches. Dend

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Shkolnyi, Oleksandr, and Yuliia Tykhonenko. "USING OF ICT DURING PREPARATION FOR EIA: WAYS TO SEARCH FOR THE OPTIMAL MODEL." Physical and Mathematical Education 30, no. 4 (2021): 13–19. http://dx.doi.org/10.31110/2413-1571-2021-030-4-002.

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Formulation of the problem. The urgency of improving the methodology of preparation for the external examination in mathematics is currently beyond doubt. Earlier we found that electronic tools in preparation for EIA in mathematics are unpopular among entrants, but positive trends in the development of ICT to prepare for testing in mathematics are also present. The current motivation for the use of technology in mathematics teaching is the current pandemic situation, when the introduction of quarantines and long periods of online learning are beginning to be perceived by students and teachers

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Lazutin, Yuriy N., Sergey P. Pyltsin, Anna Pavlovna Kharitonova, et al. "Three-year survival after combined treatment with induction chemoimmunotherapy in patients (pts) with non-small cell lung cancer (NSCLC)." Journal of Clinical Oncology 35, no. 15_suppl (2017): e20064-e20064. http://dx.doi.org/10.1200/jco.2017.35.15_suppl.e20064.

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e20064 Background: Induction chemotherapy (iCT) for NSCLC has potential advantages over adjuvant CT, high therapeutic compliance, the ability to influence the primary tumor and metastatic disease. Standard approaches to iCT improving are largely exhausted. However, the development of iCIT techniques using recombinant cytokines and assessment of the effectiveness of its clinical application remains poorly understood. Methods: Clinical trial included 65 pts. with stage IIB, IIIA (N2), IIIB (T4 ipsi. nod.) NSCLC, randomized in main (n = 33) and control (n = 32) groups with comparable clinical and

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Terpolilli, Nicole A., Walter Rachinger, Mathias Kunz, et al. "Orbit-associated tumors: navigation and control of resection using intraoperative computed tomography." Journal of Neurosurgery 124, no. 5 (2016): 1319–27. http://dx.doi.org/10.3171/2015.5.jns15330.

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OBJECT Treatment of skull base lesions is complex and usually requires a multidisciplinary approach. In meningioma, which is the most common tumor entity in this region, resection is considered to be the most important therapeutic step to avoid tumor recurrence. However, resection of skull base lesions with orbital or optic nerve involvement poses a challenge due to their anatomical structure and their proximity to eloquent areas. Therefore the main goal of surgery should be to achieve the maximum extent of resection while preserving neurological function. In the postoperative course, medical

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Cansu, Aysegul, Ali Ahmetoglu, Sibel Kul, Dilek Uzman, and Safak Ersoz. "Nonfunctional Islet Cell Tumor of the Pancreas in a Patient with Tuberous Sclerosis: A Case Report with Literature Review." Journal of Clinical Imaging Science 4 (January 30, 2014): 3. http://dx.doi.org/10.4103/2156-7514.126022.

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Islet cell tumors (ICTs) are rare tumors of the pancreas. Association of this type of tumor with tuberous sclerosis is extremely rare. Only 13 cases of pancreatic ICT with tuberous sclerosis have so far been documented in the literature. However, awareness of the association of tuberous sclerosis and ICT is important for early diagnosis and appropriate treatment of this condition. This article presents the case of a 63-year-old female with angiomyolipoma (AML) of the kidney and liver, calcified subependymal nodules and a large mass in the pancreas, which was proven to be an ICT on histopatholo

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Russell, Helen. "Later life ICT learners ageing well." International Journal of Ageing and Later Life 6, no. 2 (2012): 103–27. http://dx.doi.org/10.3384/ijal.1652-8670.1162103.

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This article is based on a qualitative study of later life computer learners and their learning experiences in Sydney, Australia. Participants who undertook lessons from peer tutors in non-formal learning environments were aged between 63 and 86. Sixteen later life learners were interviewed individually by using hermeneutic phenomenological methodology. The use of semi-structured interviews provided opportunities for participants to elaborate and reflect on their learning and lived experiences. The interviews took place over a period of seven years, from 2003 to 2010. The main aim of the study

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Wind, Karen Lycke, Lisbeth Riber, Birgitte Mayland Havelund, et al. "Intensified Induction Chemotherapy in Locally Advanced Squamous Cell Carcinoma of the Anus—A Population-Based Experience from the Danish Anal Cancer Group." Cancers 13, no. 13 (2021): 3226. http://dx.doi.org/10.3390/cancers13133226.

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Locally advanced squamous cell carcinoma of the anus (LASCCA) has a poor prognosis with a high risk of treatment failure calling for intensified therapy. We present the long-term follow-up of a nationwide cohort of LASCCA treated with intensified induction chemotherapy (ICT). The study included patients with LASCCA (T3-4N0 or T1-4N+) treated with at least one cycle of ICT (cisplatin, ifosfamide, leucoverin, and 5-flourouracil) between 1998–2018. Data were retrospectively collected from medical records, and statistics were performed in STATA 16.1. In total, 166 patients with LASCCA were identif

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Wu, Jiayan, Jie Chen, Yuanji Feng, et al. "An immune cocktail therapy to realize multiple boosting of the cancer-immunity cycle by combination of drug/gene delivery nanoparticles." Science Advances 6, no. 40 (2020): eabc7828. http://dx.doi.org/10.1126/sciadv.abc7828.

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Immune checkpoint blockade therapy (ICT) has shown potential in the treatment of multiple tumors, but suffers poor response rate in clinic. We found that even combining ICT with chemotherapy, which was wildly used in clinical trials, failed to achieve satisfactory tumor inhibition in the B16F10 model. Thus, we further constructed a previously unexplored immune cocktail therapy and realized multiple boosting of the cancer-immunity cycle. Cocktail therapy consisted of two kinds of tumor microenvironment-responsive drug and gene delivery nanoparticles to achieve specific delivery of doxorubicin a

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Toxopeus, Eelke L. A., Femke M. de Man, Nanda Krak, et al. "Association between Paclitaxel Clearance and Tumor Response in Patients with Esophageal Cancer." Cancers 11, no. 2 (2019): 173. http://dx.doi.org/10.3390/cancers11020173.

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Inter-individual variability in paclitaxel pharmacokinetics may play a role in the response to chemotherapy. Therefore, we studied the association between paclitaxel clearance and treatment response in patients with esophageal cancer. All patients who received paclitaxel (plus carboplatin) treatment for esophageal cancer between 2007 and 2013 were included. The treatment was given as neoadjuvant chemoradiotherapy (nCRT), induction chemotherapy (iCT), or palliative chemotherapy (pCT). The treatment response was assessed by the tumor regression grade (TRG) or by the RECIST1.1 criteria, respectiv

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Sánchez-Canteli, Mario, Luis Juesas, Esther Redin, et al. "Immune Cell Infiltrates and Neutrophil-to-Lymphocyte Ratio in Relation to Response to Chemotherapy and Prognosis in Laryngeal and Hypopharyngeal Squamous Cell Carcinomas." Cancers 13, no. 9 (2021): 2079. http://dx.doi.org/10.3390/cancers13092079.

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Our goal was to assess the correlation of immune parameters with the response to induction chemotherapy (ICT) in head and neck squamous cell carcinoma (HNSCC) patients. Pretreatment biopsies from 64 patients with HNSCC that received ICT were assessed for PD-L1 protein expression and density of CD8+ and FOXP3+ tumor infiltrating lymphocytes (TIL). In addition, the neutrophil-to-lymphocyte ratio (NLR) was calculated from pretreatment whole blood counts. In total, 55% of cases exhibited PD-L1 combined proportion score (CPS) positivity (≥1% stained cells). PD-L1 CPS positivity correlated with a hi

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Hawkins, Elma S., Robert Aiken, James Chandler, et al. "A randomized, double‑blind, controlled phase IIb study of the safety and efficacy of ICT‑107 in newly diagnosed patients with glioblastoma multiforme following resection and chemoradiation." Journal of Clinical Oncology 30, no. 15_suppl (2012): TPS2107. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.tps2107.

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TPS2107 Background: Tumor stem cells have been correlated with recurrence and clinical outcome in glioblastoma multiforme (GBM). ICT‑107 is an autologous vaccine consisting of the patient’s dendritic cells pulsed with 6 synthetic peptide CTL epitopes targeting the GBM tumor and tumor‑stem cell associated antigens MAGE‑1, HER‑2, AIM‑2, TRP‑2, gp100 and IL‑13Rα2. Phase I results showed a good safety profile and interesting clinical potential (ASCO, 2010, abs#2097 and ASCO, 2011, abs#2042) in 16 newly diagnosed GBM patients with a median progression-free survival (PFS) of 16.9 months (measured fr

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Hajj, Carla, Martin R. Weiser, Aoife McErlean, et al. "Induction chemotherapy followed by chemoradiotherapy and TME for high-risk locally advanced rectal cancer with and without synchronous resectable metastases." Journal of Clinical Oncology 30, no. 4_suppl (2012): 599. http://dx.doi.org/10.1200/jco.2012.30.4_suppl.599.

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599 Background: Induction chemotherapy (ICT) followed by chemoradiation (CRT) may improve tumor downsizing and disease control among patients (pts) with locally advanced rectal cancer (LARC). We retrospectively assessed the safety and short-term efficacy of ICT followed by CRT and total mesorectal excision (TME) in pts with high-risk LARC with or without synchronous resectable metastases. Methods: We reviewed records of 44 consecutive stage III (n=23) or stage IV synchronous (n=27) pts with LARC treated with ICT followed by CRT between 12/06 – 12/10. Pts had high-risk primary tumors based on a

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Rozi, Bahru. "Problematika Pendidikan Islam di Era Revolusi Industri 4.0." Jurnal Pendidikan Islam 9, no. 1 (2020): 33–47. http://dx.doi.org/10.38073/jpi.v9i1.204.

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Keberadaan pendidikan Islam di Indonesia sudah sejak lama sejak abad ke 13 M namun berbagai persoalan selalu mengiringi pendidikan Islam dari zaman penjajahan kolonial, Orde Lama, Orde Baru, Reformasi, hingga di Era Revolusi Industri 4.0. apalagi di tengah zaman industrialisasi ini memaksakan semua elemen di dalam Negara dan masyarakat berbasis digitalisasi dan manufaktur. Hal ini sangat jauh berbeda dengan paradigm pendidikan Islam yang berfokus pada pembimbingan manusia agar menjadi insan yang berspiritual Islami harus berorientasi pada teknologi dan manufaktur. Ada beberapa permasalahan yan

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Hajj, Carla, Andrea Cercek, Leonard Saltz, et al. "Induction chemotherapy followed by chemoradiotherapy and total mesenteric excision for locally advanced rectal cancer with resectable metastases." Journal of Clinical Oncology 31, no. 4_suppl (2013): 526. http://dx.doi.org/10.1200/jco.2013.31.4_suppl.526.

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526 Background: Optimal management of patients with locally advanced rectal cancer (LARC) and synchronous, resectable metastases remains controversial and treatment decisions benefit from a multidisciplinary approach. To better characterize the role of induction chemotherapy followed by chemoradiation and surgery, we evaluated patterns of distal progression and overall survival in this subset of patients. Methods: We reviewed records of 25 LARC patients with synchronous resectable metastases treated with induction chemotherapy (ICT) followed by 5-fluorouracil-based concurrent chemoradiation (C

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Fedyanin, M., A. Tryakin, D. Titov, et al. "Importance of maintenance of dose intensity (DI) during induction chemotherapy (iCT) for metastatic nonseminomatous germ cell tumors (NSGCT)." Journal of Clinical Oncology 27, no. 15_suppl (2009): e16063-e16063. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.e16063.

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e16063 Background: Cisplatin- and etoposide-based CT allows curing the majority of patients (pts) with metastatic germ cell tumor. There are limited data concerning the importance of maintenance of DI during iCT. In the retrospective study we analyzed the role of DI of iCT on metastatic NSGCT. Methods: 589 chemotherapy-naïve pts with advanced NSGCT received induction iCT from 1987 to 2006 in our center. We compared data of all pts who relapsed after iCT (147 pts) with data of 159 randomly sampled pts without relapses. During iCT all pts received classical E500P (24%) or BE500P (76%) regimens.

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Magrì, Alessandro, Giovanni Germano, Annalisa Lorenzato, et al. "High-dose vitamin C enhances cancer immunotherapy." Science Translational Medicine 12, no. 532 (2020): eaay8707. http://dx.doi.org/10.1126/scitranslmed.aay8707.

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Vitamin C (VitC) is known to directly impair cancer cell growth in preclinical models, but there is little clinical evidence on its antitumoral efficacy. In addition, whether and how VitC modulates anticancer immune responses is mostly unknown. Here, we show that a fully competent immune system is required to maximize the antiproliferative effect of VitC in breast, colorectal, melanoma, and pancreatic murine tumors. High-dose VitC modulates infiltration of the tumor microenvironment by cells of the immune system and delays cancer growth in a T cell–dependent manner. VitC not only enhances the

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Kimani, James. "INFLUENCE OF INSTITUTIONAL RELATED ON CHOICE OF TECHNOLOGY FOR THE DEVELOPMENT OF INSTRUCTIONAL MATERIALS FOR DISTANCE EDUCATION." Journal of Online and Distance Learning 1, no. 1 (2021): 29–44. http://dx.doi.org/10.47941/jodl.636.

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Purpose: no one technology can support all types of teaching and learning at a distance – the most effective approach is to combine a range of technologies. Using multiple technologies ensure that all learning styles are catered for and that significant opportunities for interaction between the learner and the tutor are provided. The general objective of the study was to institutional related on choice of technology for the development of instructional materials for distance education. Methodology: The paper used a desk study review methodology where relevant empirical literature was rev

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Salem, Philip A., Khaled W. Jabboury, Thomas M. Wheeler, and Randall Stenoien. "Personalized multimodality therapy (ICT) with immune checkpoint inhibitors (ICI), chemotherapy (CT), and targeted treatment (TT), in advanced/refractory cancer." Journal of Clinical Oncology 38, no. 15_suppl (2020): e15150-e15150. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.e15150.

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e15150 Background: Therapy for advanced/refractory malignancies is associated with poor prognosis. The combination of ICI and CT has been shown in lung and several other cancers to be superior to CT alone. Since ICI, CT, and TT have a convergent efficacy with divergent toxicity, the combination was evaluated in the treatment of these diseases. Initial evaluation was reported in JCO. 2019 37.15 suppl. e14254. Methods: Treatment was highly personalized and based on diagnosis, prior therapy, and eligibility for TT. Genomic profiling was done to determine TT. ICI included pembrolizumab in 14, nivo

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Elkerm, Y., M. Elrewiny, S. Al-Batran, E. Jager, and A. Elsaid. "Induction chemotherapy (ICT) followed by pre-operative chemoradiotherapy in locally advanced rectal cancer." Journal of Clinical Oncology 24, no. 18_suppl (2006): 13531. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.13531.

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13531 Background: Preoperative radiotherapy (RT)with or without chemotherapy (CRT) for patients (ptns) with T3,4 rectal carcinoma is increasingly accepted.We presented, 3 yrs ago, our experience with Cisplatin-5FU-Folonic(FA)regimen (FOLFC) in patns with metastatic CR carcinoma.We proved it is comparable to other regimens with lower cost. Methods: Between 10/99 & 8/04, 104 ptns between 18 and 65 year old (PS 0–1) were assessed retrospectively (24 T3 & 80 T4). Ptns received 2 months of ICT Cis(40mg/m2 D1)+FA(200mg/m2 2hrs infusion D1,2)followed by 5FU bolus(400 mg/m2 D1,2)+5FU cont inf(

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Herman, Herman. "THE NEEDS OF COLLABORATION IN OPERATING AN OPEN AND DISTANCE LEARNING INSTITUTION: UT CASE." Jurnal Pendidikan 14, no. 1 (2013): 31–37. http://dx.doi.org/10.33830/jp.v14i1.352.2013.

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This article discusses the importance of building collaboration among agencies in managing student support service for the distance student in Universitas Terbuka/UT (Indonesia Open University/IOU). As a mass-scale university with the number of students more than 600 thousand scattered in 37 provinces in Indonesia and overseas, heterogeneous socio-cultural background, offering more than 200 study program, and semester test held simultaneously, UT should be able to recruit thousands of tutors, invigilator, and executive personnel to conduct academic activities in those region. UT should manage

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Anwei, Zhao, Sun Xin, Tang Qiao Fei, Jin Ziyu, and Fa-Yu Liu. "Management Practices of Head and Neck Cancer in Chinese Tertiary Care Hospitals: A Multicenter Questionnaire-Based Survey Among Oncologists." Cancer Control 27, no. 1 (2020): 107327482090226. http://dx.doi.org/10.1177/1073274820902264.

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This survey was conducted to determine the head and neck cancer (HNC) treatment strategies followed by oncologists in Chinese hospitals. It was a questionnaire-based survey, conducted from October 2017 to January 2018 in 100 random tertiary hospitals in 21 cities of China to elicit information from oncologists on the management practices for treating HNC in China. A validated, structured questionnaire was used for formal investigation with oncologists. The questions regarding HNC types, treatment strategies used for locally advanced head and neck cancer (LA HNC) and recurrent/metastatic head a

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Zeidan, Amer M., Franklin Hendrick, Erika Friedmann, et al. "Deferasirox Is Associated with Reduced Mortality Risk in a Medicare Population with Myelodysplastic Syndromes." Blood 120, no. 21 (2012): 426. http://dx.doi.org/10.1182/blood.v120.21.426.426.

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Abstract Abstract 426 Background: While there is extensive evidence of the impact of iron chelation therapy (ICT) on clinical outcomes in thalassemia patients (pts), there is a paucity of data relevant to myelodysplastic syndromes (MDS). In this study, we examined the association between oral deferasirox (DFX) therapy and conditions potentially associated with iron overload [congestive heart failure (CHF) and endocrine disease (diabetes or thyroid)], drug side effects (renal disease), and overall mortality, among MDS pts in a U.S. Medicare cohort. Methods: MDS pts from 2005–2008 were identifie

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Hitt, R., J. Grau, A. Lopez-Pousa, et al. "Randomized phase II/III clinical trial of induction chemotherapy (ICT) with either cisplatin/5-fluorouracil (PF) or docetaxel/cisplatin/5-fluorouracil (TPF) followed by chemoradiotherapy (CRT) vs. crt alone for patients (pts) with unresectable locally advanced head and neck cancer (LAHNC)." Journal of Clinical Oncology 24, no. 18_suppl (2006): 5515. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.5515.

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5515 Background: we have previously reported that ICT plus CRT is more active than CRT alone in pts with unresectable LAHNC (Hitt et al: ASCO 2005, abstract 5578). Here we present new data of efficacy and time to progression (TTP) in this trial. Methods: Patients: eligible pts included those with unresectable LAHNC, measurable disease, adequate organ function and ECOG 0–1. Pts were stratified according to primary tumor site. Treatment: Induction chemotherapy regimens (3 cycles): PF : P 100 mg/m2 day (d) 1, then F 1000 mg/m2 c.i. d1–5 q 21d; TPF: T 75 mg/m2 d1, P 75 mg/m2 d1, F 750 mg/m2 c.i. d

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Shiraishi, Yutaka, Cai Xu, Juhee Song, Ritsuko Komaki, Brian P. Hobbs, and Steven H. Lin. "The impact of proton beam therapy on blood cell count nadir during neoadjuvant chemoradiation therapy for esophageal cancer." Journal of Clinical Oncology 35, no. 4_suppl (2017): 137. http://dx.doi.org/10.1200/jco.2017.35.4_suppl.137.

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137 Background: To analyze the blood cell count nadir, particularly grade 4 hematologic toxicities, in patients with esophageal cancer who were treated with neoadjuvant chemoradiation (nCRT) with either Proton Beam Therapy (PBT) or Intensity Modulated Radiation Therapy (IMRT) in a propensity-matched pair analysis. Methods: Esophageal cancer patients (n = 480) treated from 2005-2016 with nCRT with (n = 167) or without (n = 313) induction chemotherapy (ICT) were analyzed. White blood cell, neutrophil, lymphocyte and platelet counts nadir during ICT and CRT were obtained, and graded according to

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Yokota, Tomoya, Yoshiyuki Iida, Tomoyuki Kamijo, et al. "Which treatment strategies are the most promising for locally advanced resectable human papillomavirus-associated oropharyngeal cancers?" Journal of Clinical Oncology 37, no. 15_suppl (2019): e17556-e17556. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.e17556.

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e17556 Background: The standard of care for oropharyngeal squamous cell carcinoma (OPSCC) is surgical (S) or non-surgical (NS) approach including chemoradiation (CRT). However, CRT is associated with significant long-term toxicity. Human papillomavirus (HPV) status are associated with improved prognosis for patients (pts) with OPSCC. The aim of this study was to explore the most promising treatment strategy with maintaining survival outcomes while improving QOL for locally advanced resectable HPV-positive OPSCC. Methods: A retrospective analysis of 96 pts with locally advanced resectable HPV-p

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Hossain, Amir. "Assessing the Results of Higher Secondary Level and Its Equivalence Examinations: An Empirical Study." Global Research in Higher Education 4, no. 2 (2021): p1. http://dx.doi.org/10.22158/grhe.v4n2p1.

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This study aims to look at an assessment of the results of higher secondary level and its equivalence examinations of 2018 to unveil a 21st-century education system of Bangladesh. It aims to focus on the comparative discussion of the pass rate of different education boards. It would like to find out noticeable reasons for unsatisfactory results of HSC level learners under the ten education boards. The creative system, ICT, English, Science and Mathematics, financial constraints, lack of private tutor and teacher, strict evaluation of scripts, question paper leak, nepotism, and copying in the e

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Lussier, Danielle M., Elise Alspach, Jeffrey P. Ward, et al. "Radiation-induced neoantigens broaden the immunotherapeutic window of cancers with low mutational loads." Proceedings of the National Academy of Sciences 118, no. 24 (2021): e2102611118. http://dx.doi.org/10.1073/pnas.2102611118.

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Immunotherapies are a promising advance in cancer treatment. However, because only a subset of cancer patients benefits from these treatments it is important to find mechanisms that will broaden the responding patient population. Generally, tumors with high mutational burdens have the potential to express greater numbers of mutant neoantigens. As neoantigens can be targets of protective adaptive immunity, highly mutated tumors are more responsive to immunotherapy. Given that external beam radiation 1) is a standard-of-care cancer therapy, 2) induces expression of mutant proteins and potentiall

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Kiselevsky, M. V., I. V. Samoylenko, O. V. Zharkova, et al. "Predictive biomarkers of inhibitors immune checkpoints therapy in malignant tumors." Russian Journal of Pediatric Hematology and Oncology 8, no. 2 (2021): 73–83. http://dx.doi.org/10.21682/2311-1267-2021-8-2-73-83.

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Immune checkpoint inhibitors (ICT) therapy is a successful immunotherapy (IT) strategy that is quite effective in a number of patients with non-small cell lung cancer, melanoma, bladder cancer, breast cancer and others. Nevertheless, there is a need in predictive markers for ICT therapy for personalized IT as far as there is a large group of patients, the proportion of which varies depending on the tumor, who do not have a clinical response to such therapy. The review summarizes the theoretical aspects and results of clinical trials dedicated to various clinical efficiency predictor using mode

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Stemmelin, German R., Marta Dragosky, Adriana Vitriu, et al. "Therapeutic Approach to Advanced Follicular Lymphoma at Diagnosis: An Argentinian Survey." Blood 124, no. 21 (2014): 4408. http://dx.doi.org/10.1182/blood.v124.21.4408.4408.

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Abstract Different treatment guidelines suggest that advanced follicular lymphoma (AFL) subjects should be treated only when meeting criteria treatment, such as GELF, are present. Conversely, when absent the watch and wait (W&W) approach is recommended. However, in our country, we had the impression that in real life, a high percentage of patients without the above-mentioned criteria were treated. With the purpose of unravelling the medical approach of AFL patients at diagnosis and subsequent evolution, the Lymphoma Subcommittee of the Argentinian Society of Haematology undertook this retr

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