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Relevant bibliographies by topics / Imidazole – Toxicologie

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Academic literature on the topic 'Imidazole – Toxicologie'

Author: Grafiati

Published: 4 June 2021

Last updated: 16 February 2022

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Journal articles on the topic "Imidazole – Toxicologie"

1

Raczak-Gutknecht, Joanna, Teresa Frąckowiak, Antoni Nasal, Anita Kornicka, Franciszek Sączewski, and Roman Kaliszan. "Are Alpha-2D Adrenoceptor Subtypes Involved in Rat Mydriasis Evoked by New Imidazoline Derivatives: Marsanidine and 7-Methylmarsanidine?" Dose-Response 15, no. 2 (2017): 155932581770121. http://dx.doi.org/10.1177/1559325817701213.

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The imidazoline compounds may produce mydriasis after systemic administration to some species (rats, cats, and mice). In mydriatic activity of imidazolines, α2D-adrenoceptors subtype(s) seems to be involved. In this study, the pupil dilatory effect evoked by 2 newly synthesized imidazoline derivatives—α2-adrenoceptor agonists: marsanidine and 7-methylmarsanidine—was compared. The compounds were tested alone as well as in the presence of α2-adrenoceptor antagonists (nonselective, yohimbine, and selective toward the following α2-adrenoceptor subtypes—α2A-2-[(4,5-dihydro-1H-imidazol-2-yl)methyl]-

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2

Sadek, Kamal Usef, Afaf Mohamed Abdel-Hameed, Hisham A. Abdelnabi, and Yasser Meleigy. "An efficient green synthesis of novel 1H-imidazo[1,2-a]imidazole-3-amine and imidazo[2,1-c][1,2,4]triazole-5-amine derivatives via Strecker reaction under controlled microwave heating." Green Processing and Synthesis 8, no. 1 (2019): 297–301. http://dx.doi.org/10.1515/gps-2018-0093.

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Abstract A highly efficient multi-component one-pot synthesis of novel 1H-imidazo[1,2-a]imidazole-3-amine and imidazo[2,1-c][1,2,4]triazole-5-amine derivatives has been developed through the reaction of easily available aromatic aldehydes, benzoyl cyanide and either 2-aminoimidazole-4,5-dicarbonitrile or 3-amino-1,2,4-triazole in pyridine under controlled microwave heating. The process is environmentally friendly, is operationally simple, with short reaction time and with high yields.

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3

Behjet, Shaimaa A., and Zahraa F. Khudair. "Synthesis and Characterization of Some New Heterocyclic Derivatives and Studying of their Biological Activity (Anti-Bacteria)." INTERNATIONAL JOURNAL OF PHARMACEUTICAL QUALITY ASSURANCE 11, no. 01 (2020): 38–44. http://dx.doi.org/10.25258/ijpqa.11.1.6.

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Introduction: In this work synthesis, many kinds of heterocyclic derivatives by many steps, the first we preparation 1-(4-((1H-imidazol_2-yl-) diazenyl) phenyl) ethan-1_one. (1) by coupling of diazonium salt of p-amino acetophenone with imidazole in alkaline alcoholic media, the second step include react (1) with 2_amino_6_methylpyrimidin _4_ol in acid medium to get Schiff base derivatives(2)the last step include react(2) with (sodium azide, thioglycolic acid, glycine, alanine, Tryptophan, (2 aminobenzoic acid), (2-mercaptobenzoic acid) to give (tetrazole(3), thiazolidine(4), imidazolidine(5-7

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4

Tarnok, Zsuzsa, and Ivan Tarnok. "Histamine (HIS) degradation in microorganisms: Imidazole ring splitting and formation of imidazolyl ethanol (IMET) and imidazolyl acetic acid (IMAC) in mycobacteria." Agents and Actions 18, no. 1-2 (1986): 34–37. http://dx.doi.org/10.1007/bf01987975.

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5

Lowry, J. A., and J. T. Brown. "Significance of the imidazoline receptors in toxicology." Clinical Toxicology 52, no. 5 (2014): 454–69. http://dx.doi.org/10.3109/15563650.2014.898770.

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6

Yan Guo, Fang, Chang Ji Zheng, Meiyuan Wang, et al. "Synthesis and Antimicrobial Activity Evaluation of Imidazole‐Fused Imidazo[2,1‐ b ][1,3,4]thiadiazole Analogues." ChemMedChem 16, no. 15 (2021): 2354–65. http://dx.doi.org/10.1002/cmdc.202100122.

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7

Corell, Tim, and Gert Hasselmann. "Pharmacodynamics and Toxicology of Fenflumizole, a New Non-steroidal Anti-inflammatory Imidazole Derivative." Acta Pharmacologica et Toxicologica 53, no. 4 (2009): 288–96. http://dx.doi.org/10.1111/j.1600-0773.1983.tb03425.x.

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8

Ghasemi, Saeed, Simin Sharifi, and Javid Shahbazi Mojarrad. "Design, Synthesis and Biological Evaluation of Novel Piperazinone Derivatives as Cytotoxic Agents." Advanced Pharmaceutical Bulletin 10, no. 3 (2020): 423–29. http://dx.doi.org/10.34172/apb.2020.051.

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Purpose : In this study, a series of piperazin-2-one derivatives were prepared through bioisosteric substitution of the imidazole ring of L-778,123 (imidazole-containing FTase inhibitor) and rearrangement of groups based on the tipifarnib structure. Final compounds were evaluated for their cytotoxic activities on cancer and normal cell lines by MTT assay. Methods: Methyl α-bromophenylacetic acid and 1-(3-chlorophenyl) piperazin-2-one were synthesized using previously described methods. Methyl 2-(4-chlorophenyl)-2-(4-(3- chlorophenyl)-3-oxopiperazin-1-yl) acetate was prepared by reaction betwee

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9

Forster, R., S. D. Blowers, S. Cinelli, H. Marquardt, and J. Westendorf. "Mutagenicity testing of imidazole and related compounds." Mutation Research/Genetic Toxicology 298, no. 2 (1992): 71–79. http://dx.doi.org/10.1016/0165-1218(92)90031-t.

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10

Carballo, M. A., A. S. Hick, S. Soloneski, M. L. Larramendy, and M. D. Mudry. "Genotoxic and aneugenic properties of an imidazole derivative." Journal of Applied Toxicology 26, no. 4 (2006): 293–300. http://dx.doi.org/10.1002/jat.1132.

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Dissertations / Theses on the topic "Imidazole – Toxicologie"

1

Biard, Olivier. "Hépatotoxicité des imidazoles." Paris 5, 1995. http://www.theses.fr/1995PA05P146.

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2

Alfonso, Navarro María. "Diseño y aplicación de receptores moleculares bioinspirado en la naturaleza anfótera del anillo del imidazol." Doctoral thesis, Universidad de Murcia, 2016. http://hdl.handle.net/10803/369568.

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El desarrollo de quimiosensores para la detección eficaz de aniones y cationes es un área de gran relevancia en el campo de la Química Supramolecula, debido al importante papel que juegan estas especies en procesos biológicos, ambientales y químicos. Paralelamente, ha ido emergiendo el diseño y aplicación de los receptores heteroditópicos preorganizados para la detección simultánea de especies aniónicas y catiónicas. Dentro de este contexto, los objetivos de esta tesis doctoral se centran en el diseño, síntesis y estudio del comportamiento sensor de diferentes tipos de receptores aza-heterocíc

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3

Laignelet, Laurence. "Contribution à l'évaluation toxicologique d'un fongicide à noyau imidazole (le prochloraz) : étude de ses interactions avec le cytochrome P-450 et de son métabolisme chez le rat." Dijon, 1990. http://www.theses.fr/1990DIJOS050.

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Les fongicides à noyau imidazole sont des produits phytosanitaires largement utilisés en pratique agricole et aussi des médicaments actifs contre des mycoses humaines et animales. Les interactions imidazole-cytochrome P-450 sont la cause initiale des effets médicamenteux et toxiques de ces molécules. Par ailleurs, les herbicides de la famille des chlorophénoxyalkyles appartiennent à une nouvelle classe de cancérigènes non mutagènes : les proliférateurs de péroxysomes. Le prochloraz (1-(N-propyl-N-2-(2,4,6-trichlorophénoxy) éthyl carbamoyl) imidazole), fongicide à noyau imidazole, possède un gr

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4

García, de Miguel Cristina. "Entramats moleculars d'imidazoli-calix[4]arè." Doctoral thesis, Universitat de Barcelona, 2008. http://hdl.handle.net/10803/1640.

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Els entramats moleculars d'imidazoli-calix[4]arè constitueixen sistemes oligocatiònics macrocíclics amb un potencial atractiu en l'estudi de propietats a nivell supramolecular.<br/>Des de fa més de 20 anys la investigació en el nostre grup de reserca gira entorn de l'estudi de la química dels sistemes catiònics i oligocatiònics basats en sals d'imidazoli. Concretament, en la present Tesi Doctoral s'ha accedit a entramats moleculares d'imidazoli-calix[4]arè, la particular estructura química dels quals ha permés la formació de carbens N-heterocíclics (NHC), accedint, així, als nous complexos org

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5

Ibáñez, Jiménez Anna. "Sistemes basats en sals d’imidazoli: Plataforma pel desenvolupament de compostos d’interès químic i farmacèutic." Doctoral thesis, Universitat de Barcelona, 2013. http://hdl.handle.net/10803/108183.

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La Tesi Doctoral s’emmarca dins del projecte de recerca adreçat al estudi de la química de sistemes moleculars basats en sals d’imidazoli, que ve desenvolupant el nostre grup en els darrers anys. En concret la present Tesi Doctoral s’ha proposat una alternativa als mètodes clàssics, poc estudiada fins ara en líquids iònics, pel procés de bescanvi d’anió. La metodologia desenvolupada és senzilla d’aplicar i eficient donat que millora els rendiments descrits en la literatura, a vegades de forma substancial, proporcionant parells iònics lliures d’halur. El mètode basat en l’ús de reïnes de be

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Books on the topic "Imidazole – Toxicologie"

1

1957-, Kumar M., and Gupta V. 1966-, eds. Heterocyclic chemistry. Springer, 1998.

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2

Gupta, Radha R., Vandana Gupta, and Mahendra Kumar. Heterocyclic Chemistry II: Five-Membered Heterocycles (Heterocyclic Chemistry). Springer, 1999.

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Book chapters on the topic "Imidazole – Toxicologie"

1

Tomassoni, Anthony J. "Alpha-2 Adrenergic and Imidazoline Receptor Agonists: Clonidine, Dexmedetomidine, and Related Antihypertensives, Decongestants, and Sedatives." In Critical Care Toxicology. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-17900-1_27.

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2

Tomassoni, Anthony J. "Alpha-2 Adrenergic and Imidazoline Receptor Agonists: Clonidine, Dexmedetomidine, and Related Antihypertensives, Decongestants, and Sedatives." In Critical Care Toxicology. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-20790-2_27-1.

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