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Dissertations / Theses on the topic 'Imidazoles – Derivatives'

Author: Grafiati

Published: 4 June 2021

Last updated: 12 February 2022

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1

Björk, Malin. "Synthesis of sulfur and seleniumn heterocycles, including derivatives of imidazopyridine and benzimidazole /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-597-6/.

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2

Ierno, Hélène. "Modélisation chimique de protéines fer-soufre : synthèses et caractérisations physico-chimiques de nouveaux agrégats à ligands imidazoles." Université Joseph Fourier (Grenoble ; 1971-2015), 1995. http://www.theses.fr/1995GRE10151.

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Durant ces dernieres annees, de nombreuses proteines fer-soufre ont ete decouvertes dont le site actif est relie a l'apoproteine par des ligands non-cysteinyles ; elles presentent des proprietes spectroscopiques et electrochimiques particulieres, liees a la nature des acides amines impliques dans la coordination du cur fer-soufre. Pour modeliser la coordination d'histidines sur les centres fer-soufre, nous avons prepare des agregats a ligands imidazoles neutres. Notre demarche synthetique fait intervenir des centres fer-soufre deja formes, a ligands halogenures, sur lesquels nous realisons une

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3

Moody, David John. "Studies of some fused imidazole derivatives." Thesis, University of St Andrews, 1986. http://hdl.handle.net/10023/11011.

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The main synthetic routes to benzimidazole N-oxides are outlined and some indication is given as to the current and potential pharmacological usefulness of such materials. A claim that 4-methyl-2-nitrophenylglycine is cyclised in acetic anhydride to give either 5-methylbenzimidazole 3-oxide or the isomeric 5 methylbenzimidazolone was investigated. This work was found to be impossible to duplicate. It is established that, by employing flash vacuum pyrolysis, the claimed products can be obtained thermolytically from the starting glycine. This is the first recorded example of the formation of an

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4

Wells, Doran K. "Synthesis of imidazole derivatives related to pinacidil." Thesis, Heriot-Watt University, 1993. http://hdl.handle.net/10399/1413.

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5

Sweidan, Kamal. "Derivate des Imidazols und der Barbitursäure heterozyklische Carben-Fragmente mit p-Donor- und Akzeptor-Funktion = Imidazol and barbituric acid derivatives /." [S.l.] : [s.n.], 2006. http://deposit.ddb.de/cgi-bin/dokserv?idn=979465427.

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6

Lothian, Aileen Patricia. "The synthesis and properties of novel imidazole derivatives." Thesis, Keele University, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.296074.

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7

Galgano, Paula Decot. "Líquidos iônicos tensoativos: correlação entre estrutura molecular e propriedades micelares de cloretos de 1,3-dialquilimidazólio." Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/46/46136/tde-02052013-111536/.

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Este trabalho tem como objetivo a síntese e a determinação de propriedades micelares de líquidos iônicos tensoativos (LITs) catiônicos. Dentre as características importantes desses compostos destacamos: alta deslocalização da carga e caráter ácido no hidrogênio H2 do anel heterocíclico e a grande flexibilidade estrutural, estas são relevantes para as propriedades de soluções desses tensoativos, e, consequentemente, para suas aplicações. A influência da variação estrutural nas suas propriedades é importante para modular as propriedades micelares e, por consequência suas aplicações. A síntese de

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8

Jandu, Baljeet Kaur. "The synthesis of imidazole derivatives for the inhibition of steroid-mediated prostrate tumour growth." Thesis, Kingston University, 2013. http://eprints.kingston.ac.uk/28187/.

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The majority of prostate cancer cases are shown to be androgen-dependant for growth as the blocking of androgen production has shown to reduce the size of prostate metastasis. The biosynthesis of the androgens is catalysed by the cytochrome P450 enzyme 17a-hydroxylase/17,20-lyase (P45017a) by converting the C21 steroids (pregnenolone and progesterone) to the androgens (dehydroepiandrosterone and androstenedione, respectively). Inhibition of P45017a would therefore bring about a decrease in the level of androgen production and furthermore prevent an increase in the stimulation of androgen-depen

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9

Albuquerque, Cristina Northfleet de. "Synthèses et études physico-chimiques d'analogues du MEGAZOL, anti-parasitaire du type nitro-imidazole : étude de leur mode d'action." Toulouse 3, 1995. http://www.theses.fr/1995TOU30039.

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Le travail presente relevant d'une collaboration entre plusieurs equipes bresiliennes et celles de l'ups, porte sur l'etude de derives nitro-imidazoles susceptibles d'interagir par voie radicalaire pour produire diverses especes oxygenees. Ces composes sont utilises comme modeles pour definir les caracteristiques de nouvelles generations de molecules pouvant agir sur le metabolisme de l'oxygene de differents organismes. Cette strategie est plus particulierement appliquee au trypanosoma cruzi (responsable de la maladie de chagas, trypanosomiase de l'amerique du sud) parasite tres sensible aux m

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10

Sweidan, Kamal. "Imidazol and barbituric acid derivatives heterocyclic carbene fragments with pi-donor and acceptor properties /." [S.l. : s.n.], 2006.

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11

Olszewski, Tomasz Krzysztof. "Original syntheses of new biomolecules : from imidazole and thiazole derivatives of α-aminophosphonic acids and γ-amino-α, β-dihydroxy carboxylic acid derivatives to disaccharide mimics". Montpellier 2, 2006. http://www.theses.fr/2006MON20017.

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12

Fegy, Karine. "Ingénierie de matériaux moléculaires magnétiques : complexes de radicaux libres nitronyl nitroxydes bis-bidentes ; synthèse, structure et magnétisme." Université Joseph Fourier (Grenoble ; 1971-2015), 1997. http://www.theses.fr/1997GRE10197.

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La chimie de coordination des radicaux libres nitronyl nitroxydes est propice aux composes moleculaires magnetiques (aimants moleculaires ou transitions de spin). Cependant le caractere base de lewis faible du groupe nitroxyde >n-o limite dans de nombreux cas leur utilisation aux ions metalliques porteurs de ligands attracteurs. Pour eviter ce probleme, nous avons choisi de substituer les radicaux par des groupes donneurs. Ce travail concerne la synthese, la caracterisation structurale et l'etude des proprietes magnetiques de complexes d'ions metalliques avec les radicaux nitronyl nitroxydes p

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13

Felsmann, Marika. "Clathratbildner vom Bis-1,3-azol-Typ." Doctoral thesis, Technische Universitaet Bergakademie Freiberg Universitaetsbibliothek "Georgius Agricola&quot, 2010. http://nbn-resolving.de/urn:nbn:de:bsz:105-qucosa-26675.

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Gegenstand dieser Arbeit ist die Synthese und Charakterisierung von Bis-1,3-azol-Derivaten insbesondere im Hinblick auf ihre potentielle Einsatzfähigkeit als chemisches Sensormaterial. Nach bereits bekannten Methoden gelang es, zehn neue Bisoxazol-Derivate sowie zehn neue Dicarbonsäurediester herzustellen. Weiterhin wurden 13 neue Bisimidazol- und vier neue Lophin-Derivate synthetisiert. Die erhaltenen Röntgeneinkristallstrukturanalysen zeigen, dass vor allem lineare Bisimidazol- und Bisoxazol-Derivate gute Eigenschaften als Clathratbildner aufweisen. Die Bisoxazol-Derivate mit Pyridin als Spa

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14

Mohlala, Reagan Lehlogonolo. "Synthesis,characterisation and biological activity studies of organo-bridged metal schiff base complexes with qinoxaline derivative." Thesis, University of Limpopo, 2016. http://hdl.handle.net/10386/1706.

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Thesis (M.Sc.(Chemistry)) -- University of Limpopo, 2016<br>Imidazolyl-salicylaldemine Schiff base ligands were prepared by the condensation of different substituted salicylaldehydes with histamine dihydrochloride: 2,4-di-tert-butyl-6-{[2-(1H-imidazol-4-yl)-ethylimino]-methyl}-phenol L1; 4-methoxy-6-{[2-(1H-imidazol-4-yl)-ethylimino]-methyl}-phenol L2; 2-ethoxy-6-{[2-(1H-imidazol-4-yl)-ethylimino]-methyl]-phenol L3; 2-methyl-6-{[2-(1H-imidazol-4-yl)-ethylimino]-methyl}-phenol L4; 3-methyl-6-{[2-(1H-imidazol-4-yl)-ethylimino]-methyl}-phenol L5; 4-methyl-6-{[2-(1H-imidazol-4-yl)-ethylimino]-meth

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15

Felsmann, Marika. "Clathratbildner vom Bis-1,3-azol-Typ: Synthese, Komplexierung und sensorisch nutzbares Fluoreszenzverhalten." Doctoral thesis, TU Bergakademie Freiberg, 2009. https://tubaf.qucosa.de/id/qucosa%3A22698.

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Gegenstand dieser Arbeit ist die Synthese und Charakterisierung von Bis-1,3-azol-Derivaten insbesondere im Hinblick auf ihre potentielle Einsatzfähigkeit als chemisches Sensormaterial. Nach bereits bekannten Methoden gelang es, zehn neue Bisoxazol-Derivate sowie zehn neue Dicarbonsäurediester herzustellen. Weiterhin wurden 13 neue Bisimidazol- und vier neue Lophin-Derivate synthetisiert. Die erhaltenen Röntgeneinkristallstrukturanalysen zeigen, dass vor allem lineare Bisimidazol- und Bisoxazol-Derivate gute Eigenschaften als Clathratbildner aufweisen. Die Bisoxazol-Derivate mit Pyridin als Spa

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16

Seeyangnok, Samitthichai. "NOVEL SYNTHESIS OF DERIVATIVES OF 1,2-DIIMIDAZOLYL-BENZENE AND THEIR SILVER CARBENE COMPLEXES." University of Akron / OhioLINK, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=akron1191506703.

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17

Davis, John D. "Spectroscopic examination of the catalytic decomposition of hydrogen peroxide by a copper (II) complex of a dissymmetric Schiff base and an imidazole derivative." [Johnson City, Tenn. : East Tennessee State University], 2003. http://etd-submit.etsu.edu/etd/theses/available/etd-0715103-171753/unrestricted/DavisJ072503F.pdf.

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Thesis (M.S.)--East Tennessee State University, 2003.<br>Title from electronic t.p. ETSU ETD database URN: etd-0715103-171753. Includes bibliographical references. Also available via Internet at the UMI web site.

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18

Davis, John D. Jr. "Spectroscopic Examination of the Catalytic Decomposition of hydrogen Peroxide by a Copper (II) Complex of a Dissymmetric Schiff Base and an Imidazole Derivative." Digital Commons @ East Tennessee State University, 2003. https://dc.etsu.edu/etd/801.

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Previous studies involving copper (II) complexed with a dissymmetric Schiff base and imidazole derivatives had identified catalase activity of these complexes towards H2O2. Reactions such as this are of great interest due to the important role of copper-based complexes in biological systems. Our research has been conducted to add to the base of knowledge regarding the efforts of other researchers to investigate copper complexes that exhibit similar reactivity as copper-based proteins towards dioxygen. The copper complex chosen for this study contained a tri-dentate Schiff base adduct which,

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19

Obah, kosso Anne. "Arylsélénation et sélénocyanation d'hétérocycles riches en électrons." Electronic Thesis or Diss., Aix-Marseille, 2019. http://www.theses.fr/2019AIXM0643.

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Ce travail s’inscrit dans la recherche et le développement de nouvelles méthodologies pour la synthèse de molécules portant un groupement sélénocyané ou arylsélanyle. Dans une première partie, le trisélénodicyanure (TSD) généré à partir du malononitrile et du dioxyde de sélénium a été utilisé pour la substitution électrophile d’hétérocycles riches en électrons tels que les imidazohétérocycles, les chromèn-4-ones et également pour l’ipso-sélénocyanation d’acides arylboroniques sans l’utilisation de métaux. Cette sélénocyanation permet d’accéder rapidement et de façon fiable aux dimères diséléni

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20

Bipath, Nirvashini. "Synthesis, spectroscopic properties and cytotoxicity of boron- dipyrromethene fluorescent dyes." Thesis, 2015. http://hdl.handle.net/10321/1172.

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Submitted in fulfilment of the requirements of the Degree of Master of Technology: Chemistry, Durban University of Technology. 2014.<br>In this study, we report the synthesis of three quinolone bearing imidazole derivatives 2, 3 and 4 and two quinolone bearing BODIPY dyes 5 and 7. In the synthesis of 2, 3 and 4, the first step was the preparation of the starting compound 2-chloro-3-formyl quinoline (1); the Vilsmeier-Haack cyclisation protocol was used. Compound 1 was used with the appropriate diamine, together with POCl3 to produce 2, 3 and 4. These compounds were characterized by IR, 1H-N

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21

Zhong, Ren Hua, and 鍾仁華. "Studies on the reaction of ��-chloroformylarylhydrazine hydrochloride with pyrazole, imidazoles and 1,2,4-triazoles derivatives." Thesis, 1996. http://ndltd.ncl.edu.tw/handle/85706865936867611512.

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22

"Synthesis of novel benzimidazole derivatives and their platinum (II) complexes." Thesis, 2010. http://hdl.handle.net/10413/2614.

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Benzimidazole and its derivatives have attracted many organic chemists due to their interesting biological activities. These include activities against viruses such as, HIV, RNA, herpes (HSV-1), influenza, and cytomegalovirus (HCMV); antimicrobial and antitumor activities. Even though a lot of research has been conducted on the synthesis of benzimidazoles, factors such as, drug resistance present a need for synthesis of more structural analogues of these compounds. In chapter three, the synthesis of 2-aryl-1Hbenzimidazoles (46a-c) and 2-aryl-1-arylmethyl-1H-benzimidazoles (49a-d) is described.

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23

"Novel aspects of the chemistry of tosylmethyl isocyanide synthesis of pyrroles, indoles, and imidazoles using base-induced cycloadditions of TosMIC, or derivatives, to Michael acceptors and to aldimines /." [S.l. : [Groningen : s.n.] ; University Library Groningen] [Host], 1997. http://irs.ub.rug.nl/ppn/292813821.

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24

Jhan, Yu-Jie, and 詹昱頡. "Development of Imidazole Derivatives as Potential UV Filters." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/14423624625048593993.

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碩士<br>高雄醫學大學<br>香粧品學系碩士班<br>101<br>Many kinds of chemical sunscreens are added in skin care products to resist ultraviolet to damage the skin. However, most of the sunscreens recently have been reported to be harmful to human body. Accordingly, it is an important lesson to discover new active ingredients as novel UV filter. A series of imidazole-based compounds were investigated in this study. The sun protection was evaluated and contrasted with common sunscreens including avobenzone, benzophenone-3 and octyl p-methoxycinnamate to understand their potentials to be new choices for the sunscreen

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25

李耀峰. "Synthesis and Luminescence of Containing Imidazole derivatives Iridium Complexes." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/28170936398865301162.

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26

Sweidan, Kamal [Verfasser]. "Derivate des Imidazols und der Barbitursäure : heterozyklische Carben-Fragmente mit π-Donor- und Akzeptor-Funktion = Imidazol and barbituric acid derivatives / vorgelegt von Kamal Sweidan". 2006. http://d-nb.info/979465427/34.

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27

Li, Chi-Yi, and 李祈逸. "Synthesis and Antiproliferative Evaluation of 2,4,5-Triaryl-1H-imidazole Derivatives." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/57499294830720117890.

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碩士<br>高雄醫學大學<br>醫藥暨應用化學研究所<br>99<br>This thesis is to investigate the synthesis and antiproliferative evaluations of 2,4,5-triaryl-1H-imidazole derivatives. These newly synthesized compounds were evaluated for their antiproliferative activities against lung cancers (A549, H1299, H460), breast cancers (MB231, MCF-7), gastric cancers (AGS), cervical cancers (Hela), ovarian cancers (CE81T), esophageal cancers (OVCA) and normal (MRC-5). Results from this study indicated that the introduction of Br, OMe, or NO2 at the para-position of C-2 phenyl group displayed weak antiproliferative potency. Furth

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28

Lin, Cheng Hong, and 林政弘. "Application of Imidazole and Aminobenzanthrone Derivatives in Organic Electroluminescent Devices." Thesis, 2002. http://ndltd.ncl.edu.tw/handle/33700975778398559736.

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29

Chiu, Ying-Chang, and 邱盈彰. "Metallomesogens based on N-(2-hydroxy)alkyl substituted imidazole derivatives." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/24548624483347290155.

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博士<br>國立東華大學<br>化學系<br>97<br>Metallomesogens of the types (i) N-(2-hydroxyl)alkyl imidazole coordinated with Silver(I), Gold(I), and Palladium(II) ions (in Chapter II), (ii) Silver(I) and Gold(I) complexes of N-hexadecanyl-N´-(2-hydroxyhexadecanyl) imidazol-2-ylidenes (in Chapter III), and (iii) nanocomposites of Gold nanoparticles embedded in N,N´-di-substituted imidazolium salt (in Chapter IV) are presented. The characterizations, results, and discussions are described in each section.

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30

Ciou, Ying-Jhang, and 邱盈彰. "Mesomorphic behavior of silver complexes derived from imidazole derivative." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/08967948464769973103.

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31

WU, YU-JUNG, and 吳育蓉. "Design and Synthesis of Phenyl Imidazole Derivatives as ABC Transporters Inhibitors." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/73917485883289126483.

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碩士<br>東海大學<br>化學系<br>104<br>ABC (ATP binding-cassette) transporter proteins are mainly responsible for the cellular efflux of metabolites or toxic substances. When tumor cells are stimulated continuously by chemotherapeutic drugs, overexpression of ABC transporter protein occurs. This leads to a lack of drug accumulation for cancer patients undergoing chemotherapy. It is therefore important to develop agents which could inhibit ABC transporter proteins so that drug efficacy can be improved. In this study, three active compounds selected from high-throughput screening (31-B11, 31-C11 and 50-F3)

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32

Ekanayake, E. Vindana. "Ring closing enyne metathesis of imidazole derivatives and subsequent Diels-Alder reaction." 2007. http://hdl.handle.net/10106/901.

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33

Hsieh, Hao-Yu, and 謝皓宇. "Synthesis and Antiproliferative Evaluation of Naphtho[2,3-d]imidazole-4,9-dione Derivatives." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/04620749871088856962.

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碩士<br>高雄醫學大學<br>醫藥暨應用化學研究所<br>98<br>This thesis describes synthesis and antiproliferative evaluation of naphtho[2,3-b]furan-4,9-dione derivatives. A number of substituents have been introduced on the N-1, C-2, or C-4 position to investigate the antiproliferative structure activity relationship with respect to the kind of substituents and the position of substitution. Preliminary results indicated that (E)-1-cyclopropyl-4,9-dioxo-4,9-dihydro-naphtho[2,3-d]imidazole- 2-carbaldehyde O-2-(piperidin-1-yl)ethyl oxime (20), (Z)-N-(4-(1-ethyl-2-methyl-9-oxo-naphtho[2,3-d]imidazol-ylideneamino- phenyl)

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34

Yan, Pi-Cheng, and 顏丕承. "Design and Synthesis of Imidazole Derivatives with Iodine as Catalyst via Multi-component Reaction." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/15601793466411231560.

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碩士<br>高雄醫學大學<br>醫藥暨應用化學研究所<br>101<br>Imidazole scaffolds are important class of biologically active molecules. Its derivatives were higly used as fungicides, anti-fungal and anti-hypertensive drugs. Imidazole is widely used in the industry, which contains corrosion inhibitors, flame retardants, photographic and electronics. The multi-component reaction (MCR) is a fast and efficient synthesis strategy to afford heterocyclic derivatives in which two or more of the reactants are combined in a sequential manner to obtain the desired compound with high regioselectivity. In this thesis, we report th

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35

Chien, Rong-hong, and 簡榮宏. "The application study of imidazol derivative used for OTFT and OLED." Thesis, 2006. http://ndltd.ncl.edu.tw/handle/67051317817800491492.

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碩士<br>正修科技大學<br>化工與材料工程研究所<br>94<br>The new imidazol derivatives used for OLED and OTFT have been synthesized and the performances of device using these compounds as active materials also have been described. The absorption spectra of these compounds showed intense bands appearing in the ultraviolet or near ultraviolet part of the spectrum between 250 and 420 nm. The quinoxalylimidazolyl-based Ir(III)complexes are intensely luminescent with emission characteristic of phosphorescence from a MLCT triplet state. Organic Thin-Film Transistors using compound 2 and compound 4 as active layer showed

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36

Sun, Yu Shuang, and 孫瑀霜. "In vitro modulation of ABCG2 by AC1N5DA0 and a novel imidazole compound STK758118 with its derivatives." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/nnm32q.

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37

Lee, Guo-Chih, and 李國志. "Synthesis, Characterization, and Organic Optoelectronic Applications of Polythiophene Derivatives Containing Polycyclic Aromatic Imidazolyl Substituents." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/76896146440444931638.

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碩士<br>國立交通大學<br>影像與生醫光電研究所<br>100<br>The goal of this research is to synthesize polythiophene derivatives containing polycyclic aromatic imidazolyl substituents and to study the influence of different imidazolyl substituents on thermal, optical, and electrochemical properties. Those materials can be used as active layer for fabrication of organic solar cells. Poly(3-hexylthiophene) (P3HT) were also synthesized for comparison in this study. Polymers with high regioregularity > 95% were synthesized via the Grignard metathesis. The number-average molecular weights of polymers are in the range of

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38

Chen, Kun-Lung, and 陳坤隆. "Investigation of the 1-Substituted Imidazole Derivatives as Thermal Latent Catalysts in the Crue of Epoxy Resins." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/29281449093223156002.

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碩士<br>國立成功大學<br>化學系專班<br>93<br>Three Types of catalysts were usually applied in the molding compound of electronic industries which contain a series of imidazole, diazabicyclic derivatives (DBU and DBU) and phenolic compounds. Sometimes, the mixture compounds of diazabicyclic derivatives and phenolic compounds also were applied in the manufacture production. Due to the strong reactivity of these catalysts, the molding compounds must be storage at low temperature to prolong the pot-life. As a result, the latent catalysts have attracted much attention to maintain the long pot-life and improve th

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39

Yun, Lik-Ka, and 殷力嘉. "Study on blue phosphorescent organic light-emitting diodes with imidazole and carbazole derivatives as the host materials." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/22734772830985149841.

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碩士<br>國立臺灣大學<br>光電工程學研究所<br>105<br>In this thesis, we fabricated the blue phosphorescent organic light-emitting diodes (PhOLEDs) with bipolar carbazole- imidazole derivative host material, 9,9'',9''-(2-(1-phenyl-1H-benzo[d]imidazol-2-yl)benzene-1,3,5-triyl)tris(9H-carbazole) (o-3CbzBz) as host and iridium(III)bis[(4,6-difluorophenyl)-pyridinato-N,C2’]picolinate (FIrpic) as guest. We achieved a maximum current efficiency of 57.63 cd/A, power efficiency of 56.61 lm/W, and external quantum efficiency of 27.96% in the blue PhOLED with o-3CbzBz as host material. Then, we achieve

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40

林欣弘. "Development of Methyl-4,5-dihydro-2-methoxy-1H-imidazole-5-carboxylate derivatives as a lysine tagging reagent." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/20803978732090630082.

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碩士<br>國立清華大學<br>化學系<br>93<br>Abstract Recently, technologies with using stable isotope coding had been developed for more accurate and sensitive analysis of protein determination in proteomics. To date, isotopic reagents have targeted with the specific feature in the peptides, such as the sulfhydryl group of cysteine. Solid-phase ICAT isotopic coding method, peptide from low aboundance protein could be detected with good sensitivity and without complications from isotope effect. In this thesis, we describe an attempt to develop a similar lysine tagging reagent for solid-support-based quanti

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Chen, Yan-Yu, and 陳嬿羽. "Synthesis of Grafted Conjungated Polymers with Pendant Phenanthrenyl- Imidazole Derivatives as Acceptor Side Chain for Organic Photovoltaic Cells." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/02968091887581420779.

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碩士<br>國立高雄大學<br>化學工程及材料工程學系碩士班<br>101<br>We have synthesized two narrow-bandgap grafted conjungated polymers P1and P2 containing pendant phenanthrenyl-imidazole derivatives as acceptor units by Grignard metathesis polymerization. We studied the effects of different weight ratios of the Polymer : PCBM blends and different annealing temperatures on the performance of polymer solar cells using the blend (Polymer : PCBM) as active layers. Both P1、P2 exhibits a low band gap of 1.51eV and 1.40eV and broad absorption band from 350 to 1000 nm, which allows it to absorb more available photons from su

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CHEN, Chun-Liang, and 陳俊良. "Synthesis and Biological Evaluation of Novel Anthra[1,2-d]imidazole-6,11-dione Derivatives as Telomere-targeted Anticancer Agents." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/54157982770983330180.

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碩士<br>國防醫學院<br>藥學研究所<br>97<br>Telomere is the nucleoprotein structure at the end of eukaryotic chromosomes, and functional telomeres are essential for continued cell proliferation. Because of the end replication problem, telomere is shortened by 50-60 bases whenever cell division happens, and this erosion induces apoptosis when its length became critically short. The enzyme telomerase is able to perform this function of length extension, since it is a specialized reverse transcriptase with an endogenous RNA template on which successive telomeric repeats are synthesized. It has been approximate

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Lin, Yi-Hua, and 林宜樺. "The study of anthra [1,2-d] imidazole-6,11-dione derivatives bound to potassium form of human telomere G-quadruplex." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/25190227489270496481.

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碩士<br>國立中興大學<br>生命科學系所<br>101<br>G-quadruplexes are DNA secondary structures formed in specific G-rich sequences. DNA sequences that can form G-quadruplexes have been found in regions with biological significance, such as human telomeres and oncogene-promoter regions. G-quadruplex has emerged as a novel and potent target for anticancer drug discovery and design. Folding of telomeric DNA, d[(TTAGGG)n], into four-stranded G-quadruplex structures has been shown to inhibit the telomerase. A number of synthetic ligands have been identified to stabilize G-quadruplex structures and inhibit telomerase

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Po-Han and 邱柏翰. "Part I: Synthetic study of glucosamine-based chiralligandsPart II: Synthetic study of fluorescent imidazole derivatives with Zn(II) chelating ligand." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/56514778061424868389.

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碩士<br>中山醫學大學<br>應用化學系碩士班<br>100<br>The thesis is composed of two parts. One is the synthetic study of glucosamine based chiral ligands. D-glucosamine was reacted with 2-bromob- enzoyl chloride followed by protection of the hydroxyl groups to get the amide 129, which cyclized under tin chloride (IV) treatment to afford oxazoline 128. Coupling of the benzyl bromide moiety with amine got the desired glucosamine based chiral chelator. The second part of the thesis is the synthetic study of fluorescent imidazole derivatives with Zn(II) chelating ligand.The diphenylamine substituted 9,10-phenanthre

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Wu, Cheng-Lung, and 吳承龍. "(1) Asymmetric Synthesis of a meso-Dicarboxylic Anhydride Employing Grignard Reagent (2) Synthesis of 2-substituted-4,5-dihydro-1H-imidazole derivatives." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/83630691181120414314.

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Abu-Rayyan, Ahmed [Verfasser]. "Synthese von organischen und anorganischen Derivaten der Imidazol-2-ylidene und 2-Methylenimidazoline = Synthesis of organic and inorganic derivatives of imidazol-2-ylidenes and 2-methyleneimidazolines / vorgelegt von Ahmed Abu-Rayyan." 2005. http://d-nb.info/975795023/34.

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Mallah, Eyad Mazin [Verfasser]. "Synthesis and characterisation of novel cationic imidazolium derivatives : on the route to possible drugs = Synthese und Charakterisierung neuer kationischer Imidazol-Derivate auf dem Weg zu möglichen Wirkstoffen / vorgelegt von Eyad Mazin Mallah." 2009. http://d-nb.info/994815026/34.

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