Academic literature on the topic 'Immunohistochemistry; Squamous cell carcinoma; Type IV collagen'

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Journal articles on the topic "Immunohistochemistry; Squamous cell carcinoma; Type IV collagen"

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Fatima, Ghazi Aswad. "Collagen Type IV Expression in Well, Moderate and Poorly Differentiated Squamous Cell Carcinoma of the Oral Cavity." Journal of Dental, Oral and Maxillofacial Research 2, no. 2 (2024): 01–07. https://doi.org/10.5281/zenodo.14011957.

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<strong>ABSTRACT</strong> <strong>Background:&nbsp;</strong>Squamous cell carcinoma(SCC) is the most important and common form of cancer of the oral cavity, Having&nbsp;a very high risk of local invasion, and nodal and distant metastases. Studying the mechanisms of invasion and metastasis of&nbsp;malignant cancers has had a crucial role in developing possible therapies tools. Type VI Collagen is expressed in a variety of&nbsp;tissues and abnormal expression is Related to the invasion and progression of different types of cancer in the body.&nbsp; <strong>Aim:&nbsp;</strong>To assess whether th
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Massi, D., and A. Franchi. "Desmoplastic trichilemmoma: a case report with immunohistochemical characterization of the extracellular matrix components." Acta Dermato-Venereologica 77, no. 5 (1997): 347–49. http://dx.doi.org/10.2340/0001555577347349.

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The case of unusual desmoplastic variant of trichilemmoma arising in the neck of a 56-year-old man is reported. The tumour was characterized by the presence of a densely sclerotic stroma, surrounded by lobules of epithelial cells with features of outer root sheath differentiation, including glycogen-rich, clear cytoplasm and peripheral palisading. In the central part of the tumour, irregular cords of epithelial cells entrapped in the desmoplastic stroma were found. Differential diagnosis of this rare tumour includes invasive squamous cell carcinoma, morphealike type basal cell carcinoma, desmo
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Benediktus, Adrian, Soehartono Soehartono, and Hendradi Surjotomo. "Korelasi ekspresi LMP-1 dengan ekspresi E-chaderin dan MMP-9 pada mekanisme metastasis penderita KNF WHO tipe 3." Oto Rhino Laryngologica Indonesiana 49, no. 1 (2019): 40. http://dx.doi.org/10.32637/orli.v49i1.263.

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Latar belakang: Karsinoma nasofaring (KNF) adalah karsinoma sel skuamosa yang berasal dari epitel nasofaring. Salah satu etiologi KNF adalah infeksi Epstein-Barr virus (EBV). Pada biopsi jaringan KNF sering ditemukan genom EBV. Latent membran protein-1 (LMP-1) merupakan antigen dari EBV diekspresikan pada 65% KNF. Efek LMP-1 pada signaling salah satunya adalah memodulasi E-cadherin dan matrix metalloproteinase 9 (MMP-9) yang berperan pada proses metastasis. Metastasis adalah suatu proses yang kompleks dimana sel-sel kanker meninggalkan lokasi primer dan bermigrasi ke jaringan lain dalam tubuh.
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Hirota, Jyusui, Kazunori Yoneda, and Tokio Osaki. "Basement membrane type IV collagen in oral squamous cell carcinoma." Head & Neck 12, no. 5 (1990): 400–405. http://dx.doi.org/10.1002/hed.2880120505.

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Orlinskaya, N. Yu, D. V. Davydenko, I. L. Shlivko, and O. E. Garanina. "Setting of reliable immunohistochemical criteria for the recurrence of nodular basal cell carcinoma." CLINICAL AND EXPERIMENTAL MORPHOLOGY 9, no. 3 (2020): 43–49. http://dx.doi.org/10.31088/cem2020.9.3.43-49.

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Introduction. Basal cell carcinoma (BCC) is one of the most prevalent skin neoplasms with increasing incidence. The grade of BCC malignancy is highly variable and depends on the invasiveness and recur-rence potential. The study was aimed at identification of immunohistochemical (IHC) determinants of BCC recurrence. Materials and methods. The comparative study encompassed 10 cases of primary BCC and 10 cases of recurrent BCC. The panel of immunohistochemical targets included p53, CK8/18, Bcl-2, CK19, Collagen type IV, Desmin, CD8, Ki-67, Vimentin, VEGFR, EGFR and AR. Results. Diffuse expression
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Rivera, César. "Histological and molecular aspects of oral squamous cell carcinoma (Review)." Oncology Letters 8, no. 1 (2014): 7–11. https://doi.org/10.3892/ol.2014.2103.

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Oral squamous cell carcinoma (OSCC) represents 95% of all forms of head and neck cancer, and over the last decade its incidence has increased by 50%. Oral carcinogenesis is a multistage process, which simultaneously involves precancerous lesions, invasion and metastasis. Degradation of the cell cycle and the proliferation of malignant cells results in the loss of control mechanisms that ensure the normal function of tissues. The aim of the current review is to present the histopathological features of OSCC, including potentially malignant changes, the international classification of tumors, th
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Tamamura, Ryo, Hitoshi Nagatsuka, You-Jin Lee та ін. "Distribution of Collagen Type IV α1-6 Chains and MMP in Oral Squamous Cell Carcinoma". Journal of Hard Tissue Biology 13, № 3 (2004): 125–30. http://dx.doi.org/10.2485/jhtb.13.125.

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Nakagawa, Hideyuki, and Soroku Yagihashi. "Expression of Type IV Collagen and Its Degrading Enzymes in Squamous Cell Carcinoma of Lung." Japanese Journal of Cancer Research 85, no. 9 (1994): 934–38. http://dx.doi.org/10.1111/j.1349-7006.1994.tb02971.x.

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Tamamura, Ryo, Hitoshi Nagatsuka, Mehmet Gunduz, Hong Gong Liu, and Noriyuki Nagai. "Localization of Collagen Type IV Alpha Chains at the Basement Membrane of Oral Squamous Cell Carcinoma." Journal of Hard Tissue Biology 14, no. 2 (2005): 194–95. http://dx.doi.org/10.2485/jhtb.14.194.

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Van Duzer, Avery, Sachiko Taniguchi, Ajit Elhance, Takahiro Tsujikawa, and Naoki Oshimori. "ADAP1 promotes invasive squamous cell carcinoma progression and predicts patient survival." Life Science Alliance 2, no. 6 (2019): e201900582. http://dx.doi.org/10.26508/lsa.201900582.

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Invasive squamous cell carcinoma (SCC) is aggressive cancer with a high risk of recurrence and metastasis, but the critical determinants of its progression remain elusive. Here, we identify ADAP1, a GTPase-activating protein (GAP) for ARF6 up-regulated in TGF-β-responding invasive tumor cells, as a strong predictor of poor survival in early-stage SCC patients. Using a mouse model of SCC, we show that ADAP1 overexpression promotes invasive tumor progression by facilitating cell migration and breakdown of the basement membrane. We found that ADAP1-rich, TGF-β-responding tumor cells exhibit cytop
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Dissertations / Theses on the topic "Immunohistochemistry; Squamous cell carcinoma; Type IV collagen"

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Aikio, M. (Mari). "Novel roles for basement membrane collagens:isoform-specific functions of collagen XVIII in adipogenesis, fat deposition and eye development, and effects of the collagen IV-derived matricryptin arresten on oral carcinoma growth and invasion." Doctoral thesis, Oulun yliopisto, 2013. http://urn.fi/urn:isbn:9789526203188.

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Abstract Collagen XVIII is an evolutionarily conserved, ubiquitously-expressed basement membrane (BM) proteoglycan produced in three isoforms, the individual roles of which are largely unknown. The physiological in vivo roles of these collagen XVIII isoforms are studied here using novel genetically modified mouse strains deficient in either the short or the medium/long isoforms of the molecule. In addition, the effects of keratin-14-driven overexpression of the thrombospondin-1 (Tsp-1) –like domain, which is common to all three collagen XVIII isoforms, are studied. The findings underline the i
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