Academic literature on the topic 'In vitro floating'

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Journal articles on the topic "In vitro floating"

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Rajeshwar, V. *. Vasudha Bakshi. "FORMULATION AND IN-VITRO EVALUATION OF EPROSARTAN FLOATING TABLETS." Journal of Pharma Research 8, no. 5 (2019): 354–59. https://doi.org/10.5281/zenodo.3236721.

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<strong><em>ABSTRACT</em></strong> <strong><em>T</em></strong><em>he Eprosartan is a selective ACE-II blocking agent which is used in the treatment of hypertension. In this study Eprosartan Floating tablets were prepared by using different polymers like HPMCK4M, HPMCK15M, HPMCK100M and CARBOPOL and HPC. Fifteen formulations of floating tablets of Eprosartan were developed by direct compression technique. The F9 formulation was found to be best of all the trials. The best formulation F9 can successfully be employed as a controlled release floating drug delivery system. The floating tablets can
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Sharma, Rajesh Kumar, Naresh Kalra, Jayesh Dwivedi, G. Jeyabalan, and Gurpreet Singh. "Development, Characterization and bioavailability enhancement of oral floating sustained release beads containing Indomethacin." Indian Journal of Pharmaceutical and Biological Research 6, no. 04 (2018): 48–54. http://dx.doi.org/10.30750/ijpbr.6.4.10.

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The purpose of this research was to prepare and evaluate floating gastroretentive beads of Indomethacin an Non-steroidal anti-inflammatory agent for increased drug bioavailability. Floating beads were prepared by dripping Method using different polymers in varying ratios. The formulations were optimized on the basis of floating ability and in-vitro drug release. The floating beads were evaluated for micromeritic properties, entrapment efficiency, as well as in-vitro buoyancy study and drug release. Indomethacin was estimated in the formulation by using UV/Visible spectrophotometer (Shimazdu UV
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Singh, Km Akancha, Vivek Kumar Patel, and Abhishek Rai. "Formulation and Evaluation of Famotidine Gastroretentive Floating Tablet by Using Biopolymer." International Journal of Research and Review 9, no. 8 (2022): 21–30. http://dx.doi.org/10.52403/ijrr.20220803.

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HPMC K4M, HPMC K15M, and HPMC K100M polymers are used in this study to make floating tablets of famotidine hydrochloride. Drug Delivery systems that are floating in the stomach have a lower bulk density than gastric fluids, therefore they stay buoyant in the stomach for a lengthy period of time without impacting gastric emptying rate. In the treatment of gastroesophageal reflex disease (GERD) and peptic ulcer (PUD). Famotidine is a histamine H2 receptor antagonist (GERD). Famotidine is an excellent option for a floating drug delivery system because of its short half-life, brief time in the sto
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Jain, Nidhi, and Rahul Gupta. "Development and in vitro Evaluation of Floating Microparticles of Cimetidine." Current Research in Pharmaceutical Sciences 7, no. 1 (2017): 25–29. http://dx.doi.org/10.24092/crps.2017.070104.

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Salunkhe, Pranali Shivaji. "FORMULATION AND EVALUATION OF GASTRORETENTIVE TABLETS OF ANTIULCER DRUG." Asian Journal of Pharmaceutical and Clinical Research 9, no. 6 (2016): 48. http://dx.doi.org/10.22159/ajpcr.2016.v9i6.10360.

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ABSTRACTGastroretentive floating drug delivery system is utilised to target drug release in the stomach or to the upper part of intestine. Lansoprazole is proton pump inhibitor intended for oral administration used as antiulcer agent. The present investigation involved formulation and evaluation of Gastroretentive floating tablets of Lansoprazole for prolongation of gastric residence time with a view to deliver the drug at sustained and controlled manner in gastrointestinal tract. The tablets of Lansoprazole were prepared by direct compression method using gas generating agent and different po
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Singh, Satya Prakash, and Navneet Kumar Verma. "Formulation and Evaluation of Torsemide Granules (Sustained Release)." Journal of Drug Delivery and Therapeutics 9, no. 2-s (2019): 480–85. http://dx.doi.org/10.22270/jddt.v9i2-s.2581.

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The aim of study was to design development and optimize a controlled release system of Torsemide. to increase its bioavailability by increasing the residence time in the stomach without contact with the mucosa, and was achieved through the preparation of floating granules by melt granulation techniques. Torsemide; a loop diuretic used in the treatment of congestive heart failure and edema was chosen as the drug candidate to be formulated as gastro retentive multiparticulate system as it is a weakly basic drug with a short half life of 2-3 hrs. Gelucire 43/01 was selected as a lipid carrier in
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Clapa, Doina, Alexandru Fira, and Nirmal Joshee. "An Efficient Ex Vitro Rooting and Acclimatization Method for Horticultural Plants Using Float Hydroculture." HortScience 48, no. 9 (2013): 1159–67. http://dx.doi.org/10.21273/hortsci.48.9.1159.

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This article presents a new acclimatization method, ex vitro acclimatization in float hydroculture. This protocol ensures the ex vitro acclimatization of the plantlets obtained in vitro in the rooting stage or the ex vitro rooting and acclimatization of the shoots obtained in the multiplication stage. Our hydroculture method is different from the techniques of flotation hydroculture because no fertilizers or plant growth regulators or other biostimulators are used and water oxygenation by bubbling is not provided. Ex vitro rooting and acclimatization in one stage without an in vitro rooting st
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Gopaiah, K. Venkata, Ramya Teja Medarametla, J. N. Suresh Kumar, et al. "Advanced Granulation and Formulation Strategies for Histamine H2 Receptor Antagonists in Peptic Ulcer Disease Management." Journal of Neonatal Surgery 14, no. 10S (2025): 1000–1013. https://doi.org/10.63682/jns.v14i10s.6812.

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Present work seeks to formulate floating tablets of famotidine Hydrochloride employing HPMC K4M, HPMC K15M and HPMC K100M polymers. The bulk density of the floating drug delivery systems is lower than the gastric fluid density and therefore has the potential to be suspended in the gastric cavity for long durations of time although the rate of gastric emptying is unaffected. Famotidine is classified as a histamine H2 receptor antagonist and it is on the World Health Organization's Model List of Essential Medicines used for the treatment of peptic ulcer disease (PUD) and gastro oesophageal reflu
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Rathi, Jagdish, Mithun Bhowmick, Rahul Sharma, Sagar Panse, Rupal Pandit, and Sachin Gupta. "Development and In-vitro characterization of floating drug delivery system of ketoconazole." Journal of Drug Delivery and Therapeutics 9, no. 1 (2019): 22–29. http://dx.doi.org/10.22270/jddt.v9i1.2153.

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The oral route is increasingly being used for the delivery of therapeutic agents because the low cost of the therapy and ease of administration lead to high level of patient compliances. Floating drug delivery system (FDDS) float in the gastric fluid and prolong GRT to obtain sufficient drug bioavailability, because of their lower bulk density compared to that of the aqueous medium. The aim of the present study is to prepare floating tablets as a delivery system for controlled release of Ketoconazole. Ketoconazole is a drug of choice in antifungal category and gives significant result. Floatin
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Gaikwad, V. D., V. D. Yadav, and P. D. Jadhav. "Formulation and Evaluation of Bilayer Floating Matrix Tablets For Captopril." International Journal of Current Pharmaceutical Review and Research 4, no. 2 (2013): 27–35. https://doi.org/10.5281/zenodo.12690415.

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The importance of the present investigation was to formulate a bilayer-floating tablet (BFT)for captopril using direct compression technology. The release layer contained captopril andvarious polymers such as HPMC-K15M, PVP-K30 and Carbopol 934p, alone or incombination with the drug. HPMC, K-grade and effervescent mixture of citric acid and sodiumbicarbonate formed the floating layer. The floating mechanism and in vitro dissolution studieswere carried out in a USP 23 apparatus 2 in simulated gastric fluid (without enzyme, pH 1.2).Final formulation released approximately 95% drug in 12 hrs in v
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Dissertations / Theses on the topic "In vitro floating"

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Chapman, James Anthony. "The development of in vitro techniques capable of characterising gas powered floating dosage forms." Thesis, University of Bath, 2002. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.760809.

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Eisenächer, Friederike Martha Verfasser], Karsten [Akademischer Betreuer] [Mäder, Thomas [Akademischer Betreuer] Rades, and Jörg [Akademischer Betreuer] Kreßler. "Gastroretentive floating systems : formulation development and in vitro evaluation / Friederike Martha Eisenächer. Betreuer: Karsten Mäder ; Thomas Rades ; Jörg Kreßler." Halle, Saale : Universitäts- und Landesbibliothek Sachsen-Anhalt, 2014. http://d-nb.info/1050977823/34.

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Book chapters on the topic "In vitro floating"

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Mehta, Pooja, Caymen Novak, Shreya Raghavan, Maria Ward, and Geeta Mehta. "Self-Renewal and CSCs In Vitro Enrichment: Growth as Floating Spheres." In Methods in Molecular Biology. Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4939-7401-6_6.

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Kelynack, Kristen J. "Cell-Populated Floating Collagen Lattices: An In Vitro Model of Parenchymal Contraction." In Methods in Molecular Biology. Humana Press, 2008. http://dx.doi.org/10.1007/978-1-59745-352-3_14.

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Grace, I. M., and R. A. Ibrahim. "Elastic and Inelastic Impact Interaction of Ship Roll Dynamics with Floating Ice." In Vibro-Impact Dynamics of Ocean Systems and Related Problems. Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-00629-6_10.

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Akpabio, E. I., D. E. Effiong, T. O. Uwah, and G. Jacob. "Formulation and in-vitro Evaluation of Theophylline Floating Tablets." In Technological Innovation in Pharmaceutical Research Vol. 3. Book Publisher International (a part of SCIENCEDOMAIN International), 2021. http://dx.doi.org/10.9734/bpi/tipr/v3/2268e.

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Latha, S. Madhavi, and P. Bharghava Bhushan. "Statistical Optimization and in Vitro Evaluation of Nizatidine Floating Tablets." In Current Trends in Drug Discovery, Development and Delivery (CTD4-2022). Royal Society of Chemistry, 2023. http://dx.doi.org/10.1039/9781837671090-00586.

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Nizatidine is a histamine (H2) receptor antagonist that is indicated in the management of Gastric Esophageal Reflux Disorder, Peptic Ulcer Disease, gastric and duodenal ulcer. The bioavailabilty of Nizatidine is around 70% and the drug suffers from low permeability issues due to its hydrophilic nature. The aim of this work was to formulate and develop non effervescent floating matrix tablets of Nizatidine to increase the bioavailability of the drug by increasing gastric residence time. NEGFMT of Nizatidine were prepared using Glyceryl Laurate (GL), lactose, aerosol and magnesium stearate. 32 f
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Singhal, Peeush, Rajneesh Dutt Kaushik, and Vijay Jyoti Kumar. "Preparation and in vitro Characterisation of Solid Dispersion Floating Tablet by Effervescent Control Release Technique with Improved Floating Capabilities." In Molecular Pharmacology. IntechOpen, 2020. http://dx.doi.org/10.5772/intechopen.92187.

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In this research, an effort has been done for the development of effervescent controlled release floating tablet (ECRFT) from solid dispersions (SDs) of diclofenac sodium (DS) for upsurge the solubility and dissolution rate. ECRFT of DS was prepared by using SDs of DS and its SDs prepared with PEG as carrier using thermal method (simple fusion). SDs of DS was formulated in many ratios (1:1, 1:2, 1:3 and 1:4). Prepared SDs were optimised for its solubility, % drug content and % dissolution studies. Tablets were formulated by using optimised SDs products and all formulation was evaluated for var
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Kumar, Voleti Vijaya, Kommu Pradeep, R. Niranjan Kumar, et al. "Study on Formulation and In-vitro Characterization of Floating Microspheres of Lamivudine." In Current Overview on Pharmaceutical Science Vol. 9. B P International (a part of SCIENCEDOMAIN International), 2023. http://dx.doi.org/10.9734/bpi/cops/v9/4640c.

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Kulkarni, Deepak A., Rushikesh S. Sherkar, Avinash K. Kudhekar, Chaitali S. Shirsathe, and Swaroop R. Lahoti. "Gastroretentive Drug Delivery Systems." In Novel Drug Delivery Systems (Part 1). BENTHAM SCIENCE PUBLISHERS, 2024. https://doi.org/10.2174/9789815274165124010011.

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Administration through the oral route is the most accessible and preferred due to its many advantages. Most of the drugs administered orally show poor bioavailability due to less residing time at the gastric absorption site. To boost the bioavailability of such drugs, it is important to extend the residing time of the drug in the upper GIT, which can be achieved by using gastroretentive drug delivery systems (GRDDS). There are multiple conventional and advanced gastroretentive systems based on various mechanisms, namely high-density systems, floating systems, magnetic systems, mucoadhesive sys
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F. Suniarti, Dewi, Ria Puspitawati, Rezon Yanuar, and Ranny R. Herdiantoputri. "Curcuma Xanthorrhiza Roxb. An Indonesia Native Medicinal Plant with Potential Antioral Biofilm Effect." In Focus on Bacterial Biofilms. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.104521.

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Most common oral diseases are directly related to oral biofilm, a complex community of microorganisms inhibiting the oral cavity. Recent studies provide deeper knowledge on how free-floating bacteria form a structurally organized microecosystem and on its pathogenicity and its self-defense mechanisms; thus, creating an understanding of the challenges in eliminating oral biofilm and maintaining the balance of oral ecosystem. Chlorhexidine has been the standard oral antimicrobial agent for decades. However, studies showed that it is less effective against bacteria in the form of biofilm that lea
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Conference papers on the topic "In vitro floating"

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Abdo, A., V. Jayasinha, P. S. Spuhler, M. S. Unlu, and M. Sahin. "In Vitro Testing of Floating Light Activated Micro-Electrical Stimulators." In 2009 Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE, 2009. http://dx.doi.org/10.1109/iembs.2009.5334073.

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Schander, Andreas, Heiko Stemmann, Kristin C. Claussen, Andreas K. Kreiter, and Walter Lang. "In-Vitro and In-Vivo Longevity Evaluation of Free-Floating Intracortical Silicon-Stiffened Neural Probes*." In 2019 9th International IEEE/EMBS Conference on Neural Engineering (NER). IEEE, 2019. http://dx.doi.org/10.1109/ner.2019.8717089.

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Budianto, E., and A. Hidayatullah. "Effectivenes of K2CO3 and KHCO3 as pore forming agents on floating drug delivery system hydrogel chitosan poly(N-vinyl pyrrolidone) semi-IPN: In vitro." In PROCEEDINGS OF THE 3RD INTERNATIONAL SYMPOSIUM ON CURRENT PROGRESS IN MATHEMATICS AND SCIENCES 2017 (ISCPMS2017). Author(s), 2018. http://dx.doi.org/10.1063/1.5064061.

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Hashimoto, Shigehiro, Hiroki Yonezawa, and Shogo Uehara. "Behavior of Cell Flowing Over Oblique Micro Rectangular Groove." In ASME 2021 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2021. http://dx.doi.org/10.1115/imece2021-69696.

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Abstract Is it possible to distinguish cells with minimally-invasive method according to the characteristics of cells when moving through the flow path in vitro? A microflow channel with 45 degrees diagonal microgrooves against the mainstream direction has been manufactured by photolithography technique. The flow path between the two transparent PDMS (polydimethylsiloxane) disks (0.05 mm high, 1 mm wide, and 25 mm long) has a rectangular microgroove (4.5 μm deep, 0.2 mm long) at the bottom with variations in groove widths (0.03 mm, 0.04 mm, and 0.05 mm). The deformation and direction change of
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Shallenberger, Kurt Douglas, and Stacy Marie Fresquez. "Vito Project Overview." In Offshore Technology Conference. OTC, 2023. http://dx.doi.org/10.4043/32254-ms.

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Abstract In 2009, the Vito field was discovered in more than 4,000 ft of water approximately 150 miles offshore from New Orleans, Louisiana. The project produces from reservoirs nearly 30,000 feet below sea level. This paper introduces the challenges of the multidiscipline project from a project management perspective and to compliment and introduce the several other Vito Floating Production System (FPS) papers submitted to OTC 2023 which are listed in the references of this papar. The original Vito project execution strategy was to replicate the mega-project of Appomattox. As the industry and
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Cabrera, Jonathan Evan, Graham Patrick Bradford, and Ralph Stephen Lewthwaite. "Vito FPS: Designing a Simple, Light-Weight, Single Lift Topsides." In Offshore Technology Conference. OTC, 2023. http://dx.doi.org/10.4043/32518-ms.

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Abstract This paper provides an overview of the design of the Vito topsides production train and the overall approach to achieve a minimum technical scope, a simplistic design, and limit the payload to 10,000 st. A 10,000 st topsides target was utilized in order to fabricate a single topsides module and integrate the deck with the hull in a single lift, which were key enablers to maximize flexibility and efficiency in construction and commissioning. Efforts to design the topsides production train included focusing on an integrated approach with the wells and flow assurance teams to optimize th
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Dixon, Paul Christopher, Brady Wild, Maria Hernaiz, Keith Richard Rush, and Greg Neil Smith. "Vito Project: Host Construction and Commissioning." In Offshore Technology Conference. OTC, 2023. http://dx.doi.org/10.4043/32462-ms.

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Abstract In 2009, the Vito field was discovered in more than 1,200 m of water approximately 240 km offshore from New Orleans, Louisiana in the Gulf of Mexico (GoM). The project produces from reservoirs nearly 9,100 m below sea level. This paper provides the efficiencies in constructing the Vito FPS at a single fabrication yard, commissioning, and preparation for offshore installation. This paper is part of a Vito Project series at OTC 2023 and the other papers are listed in the references. The Vito Floating Production System (FPS) has a Lightship of 21,500 mt, Topside Lift Weight of 8,700 mt,
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Johnson, Darin P., Caspar N. Heyl, Rajiv Kamal, and Yile Li. "Vito Project: Hull / Mooring Design & Platform Installation." In Offshore Technology Conference. OTC, 2023. http://dx.doi.org/10.4043/32503-ms.

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Abstract In 2009, the Vito field was discovered in more than 4,000 ft of water approximately 150 miles offshore from New Orleans, Louisiana. The project produces from reservoirs nearly 30,000 feet below sea level. This paper provides an overview of the Hull &amp; Mooring system, executing a minimum technical scope to produce a simplistic design. This paper is part of a Vito Project series at OTC 2023, and the other papers are listed in the references. The original Vito project execution strategy was to replicate the Shell mega-project of Appomattox. As the industry and market began to change i
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