Relevant bibliographies by topics / Integrin-assisted imaging and theranostics

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers

Academic literature on the topic 'Integrin-assisted imaging and theranostics'

Author: Grafiati
Published: 3 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "Integrin-assisted imaging and theranostics"

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Kossatz, Susanne, Ambros Johannes Beer та Johannes Notni. "It’s Time to Shift the Paradigm: Translation and Clinical Application of Non-αvβ3 Integrin Targeting Radiopharmaceuticals". Cancers 13, № 23 (2021): 5958. http://dx.doi.org/10.3390/cancers13235958.

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For almost the entire period of the last two decades, translational research in the area of integrin-targeting radiopharmaceuticals was strongly focused on the subtype αvβ3, owing to its expression on endothelial cells and its well-established role as a biomarker for, and promoter of, angiogenesis. Despite a large number of translated tracers and clinical studies, a clinical value of αvβ3-integrin imaging could not be defined yet. The focus of research has, thus, been moving slowly but steadily towards other integrin subtypes which are involved in a large variety of tumorigenic pathways. Pepti
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Fan, Linxin, Doudou Huang, Yichuan Wang, et al. "Cryo-assisted exfoliation of atomically thin 2D Sb2Se3 nanosheets for photo-induced theranostics." Chemical Communications 55, no. 19 (2019): 2805–8. http://dx.doi.org/10.1039/c9cc00576e.

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Sha, Shuang, Fei Yang, Anle Wang, Honglin Jin, Zhihong Zhang, and Qiaoya Lin. "Fluorescent and quantitative mitochondrial redox imaging of tumor targeted by Octa-RGD probe." Journal of Innovative Optical Health Sciences 09, no. 04 (2016): 1642002. http://dx.doi.org/10.1142/s1793545816420025.

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Integrins, over-expressed in a broad range of cancer diseases, are widely utilized as a tumor biomarker. Metabolism investigation also plays important roles in tumor theranostics. Developing simple integrin-targetting probe and monitoring tumor metabolism will give opportunities to find ways for cancer treatment, however, the investigation of tumor metabolism with integrin receptor based probes has been rarely reported so far. Here, we developed an octavalent fluorescent probe Octa-RGD by convenient genetic method, based on one tetrameric far-red fluorescent protein (fRFP) linked with RGD pept
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Lin, Bi, Yanxing Wang, Kun Zhao, et al. "Exosome-based rare earth nanoparticles for targeted in situ and metastatic tumor imaging with chemo-assisted immunotherapy." Biomaterials Science 10, no. 3 (2022): 744–52. http://dx.doi.org/10.1039/d1bm01809d.

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In this research, a tumor exosome system DOX/2DG@E-RENPs with good biocompatibility, low immunogenicity, and a high targeting effect was proposed for theranostics with high chemo-/starvation/immunotherapy efficiency.
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Gauthé, Mathieu, Paul Sargos, Eric Barret, et al. "Potential Targets Other Than PSMA for Prostate Cancer Theranostics: A Systematic Review." Journal of Clinical Medicine 10, no. 21 (2021): 4909. http://dx.doi.org/10.3390/jcm10214909.

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Background: Prostate-specific membrane antigen (PSMA) is not sufficiently overexpressed in a small proportion of prostate cancer (PCa) patients, who require other strategies for imaging and/or treatment. We reviewed potential targets other than PSMA for PCa theranostics in nuclear medicine that have already been tested in humans. Methods: We performed a systematic web search in the PubMed and Cochrane databases, with no time restrictions by pooling terms (“prostate cancer”, “prostatic neoplasms”) and (“radioligand”, “radiotracer”). Included articles were clinical studies. The results were synt
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Li, Yang, Jichuan Kong, Huan Zhao, and Yao Liu. "Synthesis of Multi-Stimuli Responsive Fe3O4 Coated with Diamonds Nanocomposite for Magnetic Assisted Chemo-Photothermal Therapy." Molecules 28, no. 4 (2023): 1784. http://dx.doi.org/10.3390/molecules28041784.

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Nanodiamonds with magnetic resonance imaging (MRI) and targeted drug delivery to exert combined effects for biomedical applications have been considered to be an urgent challenge. Herein, a novel bio-nanoarchitectonics (Fe3O4@NDs) with simultaneous imaging and therapeutic capacities was fabricated by covalently conjugating nanodiamonds (NDs) with Fe3O4. Fe3O4@NDs exhibited better biocompatibility and excellent photothermal stability with superb photothermal conversion performance (37.2%). Fe3O4@NDs has high doxorubicin (DOX) loading capacity (193 mg/g) with pH and NIR-responsive release charac
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Huang, Jianpan, Zilin Chen, Se-Weon Park, Joseph H. C. Lai, and Kannie W. Y. Chan. "Molecular Imaging of Brain Tumors and Drug Delivery Using CEST MRI: Promises and Challenges." Pharmaceutics 14, no. 2 (2022): 451. http://dx.doi.org/10.3390/pharmaceutics14020451.

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Chemical exchange saturation transfer (CEST) magnetic resonance imaging (MRI) detects molecules in their natural forms in a sensitive and non-invasive manner. This makes it a robust approach to assess brain tumors and related molecular alterations using endogenous molecules, such as proteins/peptides, and drugs approved for clinical use. In this review, we will discuss the promises of CEST MRI in the identification of tumors, tumor grading, detecting molecular alterations related to isocitrate dehydrogenase (IDH) and O-6-methylguanine-DNA methyltransferase (MGMT), assessment of treatment effec
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Wang, Lin, Syu-Ming Lai, Cun-Zhao Li, Hsiu-Ping Yu, Parthiban Venkatesan, and Ping-Shan Lai. "D-Alpha-Tocopheryl Poly(ethylene Glycol 1000) Succinate-Coated Manganese-Zinc Ferrite Nanomaterials for a Dual-Mode Magnetic Resonance Imaging Contrast Agent and Hyperthermia Treatments." Pharmaceutics 14, no. 5 (2022): 1000. http://dx.doi.org/10.3390/pharmaceutics14051000.

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Manganese-zinc ferrite (MZF) is known as high-performance magnetic material and has been used in many fields and development. In the biomedical applications, the biocompatible MZF formulation attracted much attention. In this study, water-soluble amphiphilic vitamin E (TPGS, d-alpha-tocopheryl poly(ethylene glycol 1000) succinate) formulated MZF nanoparticles were synthesized to serve as both a magnetic resonance imaging (MRI) contrast agent and a vehicle for creating magnetically induced hyperthermia against cancer. The MZF nanoparticles were synthesized from a metallic acetylacetonate in an
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Christou, Evangelia, John R. Pearson, Ana M. Beltrán, et al. "Iron–Gold Nanoflowers: A Promising Tool for Multimodal Imaging and Hyperthermia Therapy." Pharmaceutics 14, no. 3 (2022): 636. http://dx.doi.org/10.3390/pharmaceutics14030636.

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The development of nanoplatforms prepared to perform both multimodal imaging and combined therapies in a single entity is a fast-growing field. These systems are able to improve diagnostic accuracy and therapy success. Multicomponent Nanoparticles (MCNPs), composed of iron oxide and gold, offer new opportunities for Magnetic Resonance Imaging (MRI) and Computed Tomography (CT) diagnosis, as well as combined therapies based on Magnetic Hyperthermia (MH) and Photothermal Therapy (PT). In this work, we describe a new seed-assisted method for the synthesis of Au@Fe Nanoparticles (NPs) with a flowe
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Perdigon-Lagunes, Pedro, Octavio Estevez, Cristina Zorrilla Cangas, and Raul Herrera-Becerra. "Gd – Gd2O3 multimodal nanoparticles as labeling agents." MRS Advances 3, no. 14 (2018): 761–66. http://dx.doi.org/10.1557/adv.2018.244.

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ABSTRACTLanthanide nanoparticles had the possibility to couple many imaging techniques into a sole labeling agent has awaken high expectations on personalized medicine or <<Theranostics>>. This is possible due to their intrinsic physic – chemical properties. Combining different imaging techniques physicians may provide a better treatment and perform surgical procedures that might increase the survival rate of patients. Hence, there is an enormous opportunity area for the development of lanthanide multimodal nanoparticles. For this study, we synthesized Gd – Gd2O3 nanoparticles at r
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Dissertations / Theses on the topic "Integrin-assisted imaging and theranostics"

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Achour, Oussama. "Aide au ciblage du microenvironnement tumoral par le développement d’un nano-système de détection et de traitement des tumeurs avec inhibition ciblée de l’héparanase." Thesis, La Rochelle, 2014. http://www.theses.fr/2014LAROS012/document.

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Le microenvironnement des cellules tumorales présente plusieurs particularités comme l'hypoxie, l'acidification du milieu extracellulaire et l'hypersécrétion d'enzymes hydrolytiques. Ces hydrolases, comme la cathepsine D et l'héparanase, interviennent dans les étapes de la progression tumorale et notamment l'angiogenèse. Cette thèse s'intègre dans un projet dont la finalité est de concevoir un nano-objet moléculaire enzymo-sensible qui réagirait d'une manière spécifique aux enzymes hypersécrétées dans le microenvironnement tumoral pour assurer de façon simultanée, une fonction de détection et
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Book chapters on the topic "Integrin-assisted imaging and theranostics"

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Li, Zi-Lin, Ya-Jung Shih, Chung-Che Tsai, et al. "Integrin αvβ3-Targeted Therapeutic Strategies in Pancreatic Cancers." In Acute and Chronic Pancreatitis [Working Title]. IntechOpen, 2025. https://doi.org/10.5772/intechopen.1008947.

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Pancreatic cancer is a significant health concern, primarily due to challenges in early diagnosis and limited treatment options. The increasing incidence of pancreatic cancers and the lack of effective chemotherapy underscore the need for early detection and efficient therapy. The cell surface integrin αvβ3 overexpresses in most cancers and newly growing endothelial cells crucial in cancer growth and metastasis. Novel nanotechnologies have been developed to target integrin αvβ3 and its functions for detective and therapeutic purposes. This chapter details the importance of the cell target, int
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Garg, Ashish, Vijay Sagar Madamsetty, Sumel Ashique, Vinod Gauttam, and Neeraj Mishra. "Targeted Nanocarriers-based Approach For Prostate Cancer Therapy." In Therapeutic Nanocarriers in Cancer Treatment: Challenges and Future Perspective. BENTHAM SCIENCE PUBLISHERS, 2023. http://dx.doi.org/10.2174/9789815080506123010008.

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Prostate cancer is the most common malignancy in men, with elevated morbidity and mortality. The current management, along with dope, leads to chemo defiance. On molecular imaging, many researchers have assisted with staging, restaging, early diagnosis, and, particularly, prostate cancer healing. At the site of cancer, treatment of prostate cancer, including chemo, has encountered many difficulties, such as quick clearance of dope or defiance of drug and short accumulation. Nanotechnology applications and their use in biomedicine to deliver various therapeutic carriers fitted to relieve deputy
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Pande, Vishal, Sachin Kothawade, Sharmila Kuskar, Sandesh Bole, and Dinesh Chakole. "Fabrication of Mesoporous Silica Nanoparticles and Its Applications in Drug Delivery." In Nanotechnology and Nanomaterials. IntechOpen, 2023. http://dx.doi.org/10.5772/intechopen.112428.

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Mesoporous Silica Nanoparticles (MSNs) are nano-sized particles with a porous structure that offers unique advantages for drug delivery systems. The chapter begins with an introduction to MSNs, providing a definition of these nanoparticles along with a brief historical overview. The distinctive properties of MSNs, such as high surface area, tunable pore size, and excellent biocompatibility, are discussed, highlighting their potential in drug delivery applications. The synthesis methods for MSNs are presented, including template-assisted synthesis, sol-gel method, co-condensation method, and ot
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Hara, Daiki, Ryder Schmidt, Wensi Tao, et al. "Theranostic gold nanoparticle-assisted tumor radiosensitization and imaging." In Gold Nanoparticles for Drug Delivery. Elsevier, 2024. http://dx.doi.org/10.1016/b978-0-443-19061-2.00001-8.

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Conference papers on the topic "Integrin-assisted imaging and theranostics"

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Kim, Jin Hyuk, Joon Woo Song, Yeon Hoon Kim та ін. "Targeted multimodal imaging-assisted theranostic photoactivation stabilizes inflamed atherosclerotic plaques via TGF-β dependent fibrotic replacement". У Light in Cardiology 2025, редактори Gijs van Soest, Christos Bourantas та Irina V. Larina. SPIE, 2025. https://doi.org/10.1117/12.3041008.

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