Academic literature on the topic 'Labeled Compound Synthesis'

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Dissertations / Theses on the topic "Labeled Compound Synthesis"

1

Mashni, Jamil Assad. "DEVELOPMENTS IN SIGNAL AMPLIFICATION BY REVERSIBLE EXCHANGE (SABRE) OF 15N AND 13C NUCLEI TOWARDS APPLICATIONS IN MRI." OpenSIUC, 2019. https://opensiuc.lib.siu.edu/theses/2516.

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Signal Amplification by Reversible Exchange (SABRE) is a hyperpolarization technique that utilizes parahydrogen for the NMR signal enhancement of nuclear spins. SABRE is related to Parahydrogen Induced Polarization (PHIP), another means of hyperpolarization using parahydrogen; PHIP achieves hyperpolarization via chemical reduction. Although PHIP and SABRE share many similarities in experimentation, PHIP ultimately requires the presence of an unsaturated chemical bond as well as pairwise-addition of parahydrogen. No permanent chemical change occurs during SABRE, and instead may be considered as
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2

Björkman, Margareta. "Palladium-promoted synthesis of compounds labelled with ¹¹C : Synthesis of ¹¹C-labelled prostacyclin and prostaglandin analogues." Doctoral thesis, Uppsala University, Department of Chemistry, 2000. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-1071.

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<p>Palladium-promoted reactions have been employed for the synthesis of compounds labelled with <sup>11</sup>C (t<sub>½</sub> = 20.3 min). The precursor [<sup>11</sup>C]methyl iodide was used in palladium-promoted cross-coupling reactions with organostannanes. With this method, large molecules with several functional groups, that is prostacyclin analogues, have been synthesised in up to 54 % decay-corrected radiochemical yield, calculated from [<sup>11</sup>C]methyl iodide. However, since this method did not afford reproducible yields, a second method where copper(I) was used as a co-catalyst
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3

Gillings, Nicholas Matthew. "Aziridines in the synthesis of '1'1C and '1'8F-labelled compounds." Thesis, King's College London (University of London), 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.286815.

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4

Destro, Gianluca. "Chemistry of CO₂ for the synthesis of radio-labelled compounds." Thesis, Université Paris-Saclay (ComUE), 2019. http://www.theses.fr/2019SACLS228.

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Le marquage radioisotopique est un domaine d’intérêt d’un point de vue de la recherche fondamentale en santé et, de par ses nombreuses applications, aussi bien en industrie pharmaceutique et agrochimique que dans le milieu académique. Dans ce contexte, le carbone-14 joue un rôle primordial dans le développement de nouvelles drogues et dans les études ADME et toxicologiques. Les voies de synthèse traditionnelles impliquant le ¹⁴C sont longues et multi-étapes ce qui entrave la viabilité de cette stratégie. L’objectif de cette thèse est de développer de nouvelles techniques de radiomarquage par é
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5

Chiu, Chun-ming Jack, and 趙鎮明. "Synthesis and NMR studies of N-15 labelled iminopyrans and theirsalts." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1985. http://hub.hku.hk/bib/B31207212.

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Chiu, Chun-ming Jack. "Synthesis and NMR studies of N-15 labelled iminopyrans and their salts /." [Hong Kong : University of Hong Kong], 1985. http://sunzi.lib.hku.hk/hkuto/record.jsp?B12267338.

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7

Li, Ning. "Synthesis and characterization of ¹⁰⁵Rh-labeled thiamacrocycles for use to formulate peptide receptor agents /." free to MU campus, to others for purchase, 1996. http://wwwlib.umi.com/cr/mo/fullcit?p9924957.

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8

Vasdev, Neil Chirakal R. V. Schrobilgen G. J. "Syntheses of fluorine-18 labelled compounds and radiopharmaceuticals by electrophilic fluorination /." *McMaster only, 2003.

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9

Luthra, Sajinder Kaur. "Synthesis of some 11C and 18F-labelled compounds for clinical PET studies." Thesis, Imperial College London, 1989. http://hdl.handle.net/10044/1/47545.

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10

Peng, Chen. "Synthesis of very-long-chain bifunctional and isotope-labeled compounds for biochemical investigations into novel compounds in plant cuticular waxes." Thesis, University of British Columbia, 2012. http://hdl.handle.net/2429/43752.

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Plant cuticles are the interface for plant-environment interactions, and the first barrier protecting plants from environmental stresses such as water loss and pathogens. Structurally, the cuticle consists of a hydrophobic polymer lattice, cutin, and cuticular waxes deposited inside and outside cutin. The major components of the cuticular waxes are aliphatics derived from very-long-chain (VLC) fatty acids, such as alkanes and aldehydes. Besides compounds with primary functionalities, some compounds with two or more functional groups have also been identified in cuticular waxes. However, only l
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