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Relevant bibliographies by topics / Lactones

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Academic literature on the topic 'Lactones'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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Journal articles on the topic "Lactones"

1

Faizullina, Lily Kh, Yulia A. Khalilova, Artur R. Tagirov, et al. "Evaluation of fungicidal, bactericidal and anti-tumor activities of lactones of medium and large sizes of cycles obtained from levoglucosenone." Butlerov Communications 59, no. 9 (2019): 100–105. http://dx.doi.org/10.37952/roi-jbc-01/19-59-9-100.

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Medium and large lactones attract the attention of chemists by the uniqueness of their structure, versatile biological activity and limited availability. Among the secondary metabolites of this group, β-lactones are more common, then γ- and δ-lactones, classical and non-classical macrolides, polyene antibiotics, spiro-macrolides and macrolactones. On the basis of many lactones, important preparations of the most diverse pharmacological action have been obtained. Earlier, we proposed a 3-stage scheme for the synthesis of chiral lactones of medium and large size based on levoglucosenone. The lac

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Schaefer, Amy L., Terumi A. Taylor, J. Thomas Beatty, and E. P. Greenberg. "Long-Chain Acyl-Homoserine Lactone Quorum-Sensing Regulation of Rhodobacter capsulatus Gene Transfer Agent Production." Journal of Bacteriology 184, no. 23 (2002): 6515–21. http://dx.doi.org/10.1128/jb.184.23.6515-6521.2002.

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ABSTRACT Many proteobacteria use acyl-homoserine lactones as quorum-sensing signals. Traditionally, biological detection systems have been used to identify bacteria that produce acyl-homoserine lactones, although the specificities of these detection systems can limit discovery. We used a sensitive approach that did not require a bioassay to detect production of long-acyl-chain homoserine lactone production by Rhodobacter capsulatus and Paracoccus denitrificans. These long-chain acyl-homoserine lactones are not readily detected by standard bioassays. The most abundant acyl-homoserine lactone wa

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Ulrich, Ricky L. "Quorum Quenching: Enzymatic Disruption of N-Acylhomoserine Lactone-Mediated Bacterial Communication in Burkholderia thailandensis." Applied and Environmental Microbiology 70, no. 10 (2004): 6173–80. http://dx.doi.org/10.1128/aem.70.10.6173-6180.2004.

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ABSTRACT Many species of gram-negative bacteria communicate by synthesizing, secreting, and responding to N-acylhomoserine lactones (AHLs), a mechanism termed quorum sensing. Several investigations have characterized numerous AHL-degrading enzymes (AiiA lactonases) encoded by environmental isolates of Bacillus spp. The Burkholderia thailandensis quorum system is comprised of at least three AHL synthases (AHSs) and five transcriptional regulators belonging to the LuxIR class of proteins. Expression of the Bacillus anthracis (Ames strain) AiiA lactonase in B. thailandensis completely abolished t

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Cambie, Richard C., Lorna H. Mitchell, and Peter S. Rutledge. "Acid-Promoted Fries Rearrangements of Benzannulated Lactones." Australian Journal of Chemistry 51, no. 12 (1998): 1167. http://dx.doi.org/10.1071/c98023.

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The scope of acid-promoted Fries rearrangements of benzannulated lactones has been examined. The reaction is applicable to seven-membered lactones possessing a sufficiently activated aromatic ring but not to six-membered lactones, and it proceeds in higher yield for diterpenoid lactones than for lower molecular weight lactones. The structures of the 2,6-methano-bridged benzoxocin side products (23), (24), and (25) from rearrangement of the diterpenoid lactone (11) have been assigned.

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Surowiak, Alicja K., Lucyna Balcerzak, Stanisław Lochyński, and Daniel J. Strub. "Biological Activity of Selected Natural and Synthetic Terpenoid Lactones." International Journal of Molecular Sciences 22, no. 9 (2021): 5036. http://dx.doi.org/10.3390/ijms22095036.

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Terpenoids with lactone moieties have been indicated to possess high bioactivity. Certain terpenoid lactones exist in nature, in plants and animals, but they can also be obtained by chemical synthesis. Terpenoids possessing lactone moieties are known for their cytotoxic, anti-inflammatory, antimicrobial, anticancer, and antimalarial activities. Moreover, one terpenoid lactone, artemisinin, is used as a drug against malaria. Because of these abilities, there is constant interest in new terpenoid lactones that are both isolated and synthesized, and their biological activities have been verified.

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Klinotová, Eva, Václav Křeček, Jiří Klinot та ін. "An unusual reaction of a bridged triterpenoid α-diketone with acetic anhydride". Collection of Czechoslovak Chemical Communications 56, № 12 (1991): 2917–35. http://dx.doi.org/10.1135/cccc19912917.

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3β-Acetoxy-21,22-dioxo-18α,19βH-ursan-28,20β-olide (IIIa) reacts with acetic anhydride in pyridine under very mild conditions affording β-lactone IVa and γ-lactones Va and VIIa as condensation products. On reaction with pyridine, lactones Va and VIIa undergo elimination of acetic acid to give unsaturated lactones VIIIa and IXa, respectively. Similarly, the condensation of 20β,28-epoxy-21,22-dioxo-18α,19βH-ursan-3β-yl acetate (IIIb) with acetic anhydride leads to β-lactone IVb and γ-lactone Vb; the latter on heating with pyridine affords unsaturated lactone VIIIb and 21-methylene-22-ketone Xb.

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Bergonzi, Celine, Michael Schwab, Eric Chabriere, and Mikael Elias. "The quorum-quenching lactonase from Alicyclobacter acidoterrestris: purification, kinetic characterization, crystallization and crystallographic analysis." Acta Crystallographica Section F Structural Biology Communications 73, no. 8 (2017): 476–80. http://dx.doi.org/10.1107/s2053230x17010640.

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Lactonases comprise a class of enzymes that hydrolyze lactones, including acyl-homoserine lactones (AHLs); the latter are used as chemical signaling molecules by numerous Gram-negative bacteria. Lactonases have therefore been demonstrated to quench AHL-based bacterial communication. In particular, lactonases are capable of inhibiting bacterial behaviors that depend on these chemicals, such as the formation of biofilms or the expression of virulence factors. A novel representative from the metallo-β-lactamase superfamily, named AaL, was isolated from the thermoacidophilic bacterium Alicyclobact

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Kovács, Balázs, Péter Püski, Ákos Bajtel, et al. "Targeted Screening and Quantification of Characteristic Sesquiterpene Lactones in Ambrosia artemisiifolia L. at Different Growth Stages." Plants 13, no. 15 (2024): 2053. http://dx.doi.org/10.3390/plants13152053.

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Sesquiterpene lactones are specialized plant metabolites with promising pharmacological activities. These metabolites are characteristic marker compounds for the aerial parts of Ambrosia artemisiifolia. Numerus sesquiterpene lactones have been isolated from ragweed; however, there is no information on their bioproduction and quantification throughout the life cycle of the plant. The sesquiterpene lactone content of ragweed samples collected in Szeged and Nyíri was analyzed using HPLC. Significant differences in the amount and bioproduction rhythm of sesquiterpene lactones were found between th

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Gładkowski, Witold. "TRZYMYWANIE I WŁAŚCIWOŚCI BIOLOGICZNE RACEMICZNYCH I OPTYCZNIE CZYNNYCH LAKTONÓW Z PIERŚCIENIEM AROMATYCZNYM W POZYCJI β". Wiadomości Chemiczne 77, № 5 (2023): 509–31. https://doi.org/10.53584/wiadchem.2023.05.5.

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Natural and synthetic lactones containing an aromatic ring exhibit a number of biological properties, e.g. antiproliferative, antifeedant or antimicrobial activity. This review deals with the synthesis and biological properties of lactones containing an aromatic substituent in the β-position of the lactone ring. The described group of compounds includes halolactones, hydroxylactones, unsaturated lactones and products of reductive dehalogenation of iodolactones. In addition to chemical transformations, biotechnological methods for obtaining optically active lactones have also been described, in

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Tănase, Constantin, Lucia Pintilie, and Raluca Elena Tănase. "Lactones in the Synthesis of Prostaglandins and Prostaglandin Analogs." International Journal of Molecular Sciences 22, no. 4 (2021): 1572. http://dx.doi.org/10.3390/ijms22041572.

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In the total stereo-controlled synthesis of natural prostaglandins (PGs) and their structural analogs, a vast class of compounds and drugs, known as the lactones, are encountered in a few key steps to build the final molecule, as: δ-lactones, γ-lactones, and 1,9-, 1,11-, and 1,15-macrolactones. After the synthesis of 1,9-PGF2α and 1,15-PGF2α lactones, many 1,15-lactones of E2, E3, F2, F3, A2, and A3 were found in the marine mollusc Tethys fimbria and the quest for understanding their biological role stimulated the research on their synthesis. Then 1,9-, 1,11-, and 1,15-PG lactones of the drugs

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Dissertations / Theses on the topic "Lactones"

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Wheatley, Joseph R. "Lactones in synthesis." Thesis, University of Oxford, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.337424.

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Shangula, Suha. "Effect of paraoxonase (PON1) on lactones and ROS induced DNA damage." Thesis, University of Manchester, 2018. https://www.research.manchester.ac.uk/portal/en/theses/effect-of-paraoxonase-pon1-on-lactones-and-ros-induced-dna-damage(928ac761-7039-4f6f-9135-40a6f71b9465).html.

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Paraoxonase 1 (PON1) is an enzyme synthesised in the liver that is associated with High Density Lipoprotein (HDL) and increasingly with a number of human diseases, including cardiovascular disease and cancer. PON1 is (i) a lactonase, hydrolysing aliphatic and aromatic lactones, (ii) a phosphotriesterase, acting on certain organophosphates and (iii) a peroxidase that combats lipid oxidation. The aim of this study was to investigate the extent to which PON1 might impact on the levels of lactone-induced and oxidative DNA damage. Initially, the plasmid DNA (pDNA) nicking assay was used to show tha

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Arasa, Bertomeu Mª Mercè. "Nous termoestables epoxídics modificats amb gamma-lactones i bis-gamma-lactones condensades." Doctoral thesis, Universitat Rovira i Virgili, 2009. http://hdl.handle.net/10803/9033.

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Aquest treball s'emmarca en el camp dels materials termoestables amb aplicacions en recobriments o encapsulants per microelectrònica i pretén l'obtenció de materials amb millor durabilitat i que després del temps d'ús puguin ser degradats i permetin la recuperació del material electrònic, el que constitueix una gran avantatja des del punt de vista mediambiental. L'estratègia escollida ha estat la copolimerització de diglicidilèter de bisfenol A (DGEBA) amb mono--lactones i bis--lactones utilitzant diversos triflats de terres rares i el BF3·MEA com iniciadors catiònics i varies

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Fairbanks, Antony J. "Sugar lactones in synthesis." Thesis, University of Oxford, 1993. http://ora.ox.ac.uk/objects/uuid:44329487-5d08-4df4-8baf-fc682d4bc9cc.

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This thesis describes the synthesis of some novel carbohydrate lactones and their uses as starting materials in (a) the syntheses of various polyfunctionalised cyclopentanes, via intramolecular aldol condensations, (b) the synthesis of 1-epihydantocidin, in which the crucial synthetic step involves a novel transformation induced by tetra-n-propylammonium perruthenate, and (c) the syntheses of various tetrahydrofurans and tetrahydropyrans. The syntheses of 3,4-O-isopropylidene and cyclohexylidene altrono and allono-1,5-lactones via Kiliani ascension of protected forms of D-ribose are described.

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Maughan, K. "Grignard reactions with lactones." Thesis, University of Nottingham, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.356029.

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Mitchell, Helen Joy. "Stereocontrol with diphenylphosphinoyl lactones." Thesis, University of Cambridge, 1995. https://www.repository.cam.ac.uk/handle/1810/271942.

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Rogers, Paul S. "Sugar lactones in organic synthesis." Thesis, University of Oxford, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.425897.

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Simone, Michela A. "Studies on branched sugar lactones." Thesis, University of Oxford, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.497098.

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Toczek, Judy. "Synthetic studies on terpenoid lactones." Thesis, Brunel University, 1985. http://bura.brunel.ac.uk/handle/2438/7401.

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A novel stereoselective route has been developed to a vernolepin intermediate in nine steps from 2-phenylthiocyclopentenone. During this research, a regiospecific method for the alkylation of the Δ5,6 - tetrahydroindanone system has been achieved. In addition, the synthetic route demonstrates a means of differentiating between two carboxylic acid functions via a selective lactonisation. The first total ynthesis of boonein has also been completed, in 3% yield from cyclopentadiene. This route uses a chlorine atom to direct the stereo- and regiochemical outcome of most of these reaction.

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Dumeunier, Raphaël. "New methodologies towards lactones and methylene-lactones : application to the total synthesis of Polycavernoside A." Université catholique de Louvain, 2004. http://edoc.bib.ucl.ac.be:81/ETD-db/collection/available/BelnUcetd-05242004-130732/.

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Methylene-butyrolactones are readily accessed by two methodologies based on a particular ene reaction. Both methodologies have been applied to the synthesis of the northern fragment of Polycavernoside. A reverse Julia reaction was used as the key step of a new methodology towards triene frameworks ; a mechanistic study revealed the unexpected role of triflic acid in the field of metal triflates catalysed acylation of alcohols, and a new tandem Brook rearrangement-allylation sequence was developed in the viewpoint of an improved total synthesis of Polycavernoside A.

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Books on the topic "Lactones"

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Sülsen, Valeria Patricia, and Virginia Susana Martino, eds. Sesquiterpene Lactones. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-78274-4.

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Ogliaruso, Michael A. Synthesis of lactones and lactams. Wiley, 1993.

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Janecki, Tomasz, ed. Natural Lactones and Lactams. Wiley-VCH Verlag GmbH & Co. KGaA, 2013. http://dx.doi.org/10.1002/9783527666911.

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Vercruysse, J., and R. S. Rew, eds. Macrocyclic lactones in antiparasitic therapy. CABI, 2002. http://dx.doi.org/10.1079/9780851996172.0000.

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Toczek, Judy. Synthetic studies on terpenoid lactones. Brunel University, 1985.

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J, Vercruysse, and Rew Robert S, eds. Macrocyclic lactones in antiparasitic therapy. CABI Pub., 2002.

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Ogliaruso, Michael A., and James F. Wolfe, eds. Synthesis of Lactones and Lactams (1993). John Wiley & Sons, Inc., 1993. http://dx.doi.org/10.1002/9780470772522.

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William, Hutchens T., Lönnerdal Bo 1938-, and International Symposium on Lactoferrin: Interactions and Biological Functions (2nd : 1995 : Honolulu, Hawaii), eds. Lactoferrin: Interactions and biological functions. Humana Press, 1997.

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9

Mcnaughton-Smith, Grant Andrew. Synthetic approaches to the ascidiatrienolides and other medium ring lactones. University of East Anglia, 1993.

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Serkerov, Siradzhaddin Veli ogly. Terpenoidy i fenolproizvodnye rasteniĭ semeĭstv: Asteraceae i Apiaceae. CBS, 2005.

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Book chapters on the topic "Lactones"

1

Etienne, Y., and N. Fischer. "β-Lactones." In Chemistry of Heterocyclic Compounds: A Series Of Monographs. John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470239704.ch6.

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Sülsen, Valeria P., and Virginia S. Martino. "Overview." In Sesquiterpene Lactones. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-78274-4_1.

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Lombardo, María E., and Alcira Batlle. "Mode of Action on Trypanosoma and Leishmania spp." In Sesquiterpene Lactones. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-78274-4_10.

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Lozano, Esteban, Renata Spina, Patricia Barrera, Carlos Tonn, and Miguel A. Sosa. "Contribution of Microscopy for Understanding the Mechanism of Action Against Trypanosomatids." In Sesquiterpene Lactones. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-78274-4_11.

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Castelli, María Victoria, and Silvia Noelí López. "Effects on Other Microorganisms." In Sesquiterpene Lactones. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-78274-4_12.

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Anesini, Claudia A., María Rosario Alonso, and Renzo F. Martino. "Antiproliferative and Cytotoxic Activities." In Sesquiterpene Lactones. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-78274-4_13.

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Alonso, María Rosario, Claudia A. Anesini, and Renzo F. Martino. "Anti-inflammatory Activity." In Sesquiterpene Lactones. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-78274-4_14.

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Schmidt, Thomas J. "Structure-Activity and Activity-Activity Relationships of Sesquiterpene Lactones." In Sesquiterpene Lactones. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-78274-4_15.

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Giberti, Gustavo C. "Ancient and Modern Concepts About the Asteraceae Taxonomy." In Sesquiterpene Lactones. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-78274-4_2.

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Alves, Mateus Feitosa, Luciana Scotti, Fernando Batista Da Costa, and Marcus Tullius Scotti. "Chemotaxonomic Study of Sesquiterpene Lactones of Asteraceae: Classical and Modern Methods." In Sesquiterpene Lactones. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-78274-4_3.

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Conference papers on the topic "Lactones"

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Plotuna, Ana-Maria, Ionela Hotea, Corina Badea, Alexandra Ban-Cucerzan, and Emil Tirziu. "DONKEY MILK ACROSS DIFFERENT STAGES OF LACTATION: A NUTRITIONAL ASSET FOR SUSTAINABLE FARMING AND SOCIAL IMPACT." In SGEM International Multidisciplinary Scientific GeoConference. STEF92 Technology, 2024. https://doi.org/10.5593/sgem2024v/6.2/s24.07.

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The social significance of donkey milk for human health stems from its potential advantages for vulnerable populations, including children and those with special dietary needs. The variation in its composition throughout lactation indicates that it can be adapted to fulfil the specific nutritional demands of these groups. The focus of this paper is to investigate the chemical profile of donkey milk and the changes that occur during lactation. The study was performed on samples taken at various stages of lactation, from colostrum to milk. The results revealed fluctuations in protein, fat, lacto

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Han, Yanlin, Paul Hellier, Jincheng Wu, and Nicos Ladommatos. "In-Cylinder Sampling Analysis of Soot Precursors during Bio-Derived Lactone Combustion in a Single-Cylinder Diesel Engine." In Energy & Propulsion Conference & Exhibition. SAE International, 2024. http://dx.doi.org/10.4271/2024-01-4309.

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<div class="section abstract"><div class="htmlview paragraph">The development of new fuels for internal combustion engines (ICE) requires further technical support by understanding the pollutant formation mechanism in various phases of combustion so that emissions can be minimised. This research will therefore utilize a bespoke in-cylinder sampling system to analyse the precursors of Polycyclic Aromatic Hydrocarbons (PAHs) and Particulate Matter (PM) during bio-derived lactone combustion in a single-cylinder diesel engine. The sampling system was composed of a poppet-type in-cylind

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Levovnik, Bojan D., Aleksa P. Alargić, Miloš M. Svirčev, and Goran I. Benedeković. "Building a 3D QSAR model with isopropylidene analogs of cytotoxic styryl-lactones." In 2nd International Conference on Chemo and Bioinformatics. Institute for Information Technologies, University of Kragujevac, 2023. http://dx.doi.org/10.46793/iccbi23.559l.

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Styryl-lactones are a class of natural products and related analogs that exhibit diverse biological activities, including anticancer, anti-inflammatory, and antimicrobial properties. Since these compounds are routinely obtained in our laboratory from their O-isopropylidene precursors, we envisioned the project to examine and compare their respective structures and in-vitro activities. This paper presents a basic 3D-QSAR steric model built on a small set of 11 selected O-isopropylidene and styryl-lactone (particularly [3.3.0]furofuranone) ligands and their in vitro activities against an MCF-7 c

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Kovács, B., N. Szemerédi, N. Kúsz, et al. "Antiproliferative sesquiterpene lactones from Ambrosia artemisiifolia L." In GA – 70th Annual Meeting 2022. Georg Thieme Verlag KG, 2022. http://dx.doi.org/10.1055/s-0042-1759242.

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Kovács, Balázs. "Sesquiterpene lactones of Ambrosia artemisiifolia." In Symposium of Young Researchers on Pharmacognosy. Department of Pharmacognosy, University of Szeged, Faculty of Pharmacy, 2022. http://dx.doi.org/10.14232/syrpharmacognosy.2022.b1.

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MAKEMSON, JOHN, and ANATOL EBERHARD. "MEASUREMENT OF ACYL HOMOSERINE LACTONES WITH MASS SPECTROMETRY." In Proceedings of the 11th International Symposium. WORLD SCIENTIFIC, 2001. http://dx.doi.org/10.1142/9789812811158_0028.

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Reinhardt, JK, AM Klemd, O. Danton, et al. "Absolute configuration of sesquiterpene lactones with potent immunosuppressant activity." In 67th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA) in cooperation with the French Society of Pharmacognosy AFERP. © Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-3399849.

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Ito, Hiroshi, Hoa D. Truong, and Phil J. Brock. "Lactones in 193 nm resists: What do they do?" In SPIE Advanced Lithography, edited by Clifford L. Henderson. SPIE, 2008. http://dx.doi.org/10.1117/12.772919.

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Cherepanov, Igor S., and Olga O. Botalova. "Lactones formation during monosaccharide's caramelization in ethanolic-aqueous solutions." In PROCEEDINGS OF INTERNATIONAL CONFERENCE ON RECENT TRENDS IN MECHANICAL AND MATERIALS ENGINEERING: ICRTMME 2019. AIP Publishing, 2020. http://dx.doi.org/10.1063/5.0018037.

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Yoon, Kwang-Sub, Dong-Won Jung, Sook Lee, et al. "Novel 193-nm photoresist based on Olefin-containing lactones." In 26th Annual International Symposium on Microlithography, edited by Francis M. Houlihan. SPIE, 2001. http://dx.doi.org/10.1117/12.436902.

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Reports on the topic "Lactones"

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Westwood, James H., Yaakov Tadmor, and Hanan Eizenberg. Identifying the genes involved in host root perception by root parasitic weeds: Genetic and transcriptomic analysis of Orobanche hybrids differing in signal response specificity. United States Department of Agriculture, 2013. http://dx.doi.org/10.32747/2013.7598145.bard.

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Seeds of the root parasitic plants of the genus Orobanchegerminate specifically in response to host-derived germination signals, which enables parasites to detect and attack preferred hosts. The best characterized class of germination stimulants is the strigolactones (SL), although some species respond to sesquiterpene lactones such as dehydrocostuslactone (DCL). Despite great progress in characterizing the SL signaling system in plants, the mechanism(s) by which parasite species detect specific compounds remains poorly understood. The goal of our project was to identify and characterize the g

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Bazer, Fuller W., Arieh Gertler, and Elisha Gootwine. Role of Placental Lactogen in Sheep. United States Department of Agriculture, 2001. http://dx.doi.org/10.32747/2001.7574339.bard.

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Central problems in sheep and dairy cattle production are reproductive failure due to embryonic/fetal mortality and low birth weights, especially in prolific breeds, and reduced milk yields which adversely affect neonatal survival and economy of production. The sheep placenta expresses lactogenic (ovine placental lactogen, oPL) and somatogenic (ovine placental growth hormone, oGH) hormones. Our research has focused on the biological roles of oPL and oGH in function of the uterine endometrium during gestation and the mammary gland during pregnancy and lactation. Major conclusions were that: ( 1

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Spencer, Thomas E., Elisha Gootwine, Arieh Gertler, and Fuller W. Bazer. Placental lactogen enhances production efficiency in sheep. United States Department of Agriculture, 2005. http://dx.doi.org/10.32747/2005.7586543.bard.

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The key objectives of this BARD project were to: (1) study long-term effects of immunization of prepubertal ewes against recombinant ovine placental lactogen (roPL) on subsequent birth weights of their lambs and their milk production; (2) optimize the anti-roPL immunization protocol using adjuvant preparations acceptable to producers and regulatory agencies; and (3) determine the physiological mechanism(s) whereby immunization against oPL increases fetal growth and development and mammogenesis. These objectives were based on key findings from a previous BARD project that: (a) immunization of e

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Ulrich, Ricky L. Quorum Quenching: Enzymatic Disruption of N-Acylhomoserine Lactone-Mediated Bacterial Communication in Burkholderia thailandensis. Defense Technical Information Center, 2004. http://dx.doi.org/10.21236/ada428608.

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Joel, Daniel M., John C. Steffens, and Alfred M. Mayer. Host-Elicited Germination and Mechanism of Penetration in Broomrape (Orobanche Spp.). United States Department of Agriculture, 1993. http://dx.doi.org/10.32747/1993.7568107.bard.

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Orobanche is an important parasitic weed. For developing novel methods for its control, a thorough understanding of crucial stages of its development is needed. Therefore, the objectives of this project were characterization of Orobanche germination stimulants, analysis of mechanisms of haustorial penetration, and characterization and isolation of penetration enzymes. The first highly potent natural germination stimulant for Orobanche was isolated from sunflower and identified by high-field 1D (1H and 13C), 2D (1H-1H COSY, HMQC, HMBC)-NMR, GC.FT-IR, and GC.MS as costuslactone, a guaiane type s

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Tachea, Firehiwot, Fabrice Masson, Chyi-Shin Chen, et al. Production of chemical intermediate triacetic acid lactone (TAL) via bacterial fermentation of deconstructed lignin: CRADA Final Report. Office of Scientific and Technical Information (OSTI), 2017. http://dx.doi.org/10.2172/1393453.

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Ron, Eliora, and Eugene Eugene Nester. Global functional genomics of plant cell transformation by agrobacterium. United States Department of Agriculture, 2009. http://dx.doi.org/10.32747/2009.7695860.bard.

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The aim of this study was to carry out a global functional genomics analysis of plant cell transformation by Agrobacterium in order to define and characterize the physiology of Agrobacterium in the acidic environment of a wounded plant. We planed to study the proteome and transcriptome of Agrobacterium in response to a change in pH, from 7.2 to 5.5 and identify genes and circuits directly involved in this change. Bacteria-plant interactions involve a large number of global regulatory systems, which are essential for protection against new stressful conditions. The interaction of bacteria with

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Lee, Yew-Jin, Yann Shiou Ong, and Timothy Ter Ming Tan. Lower secondary science integrative activities: Fostering scientific practices in Singapore [Systems: Lactose intolerance]. National Institute of Education, Nanyang Technological University, Singapore, 2024. http://dx.doi.org/10.32658/10497/27067.

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Spiers, Donald, Arieh Gertler, Harold Johnson, and James Spain. An In Vitro and In Vivo Investigation of the Diverse Biological Activities of Bovine Placental Lactogen. United States Department of Agriculture, 1993. http://dx.doi.org/10.32747/1993.7568087.bard.

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In order to understand the structure-function relationship of bovine placental lactogen (bPL) and initiate production of material for in vivo testing, 28 different bPL analogues were prepared by either truncation or site-directed mutagenesis. The effect of these mutations was determined by measuring binding capacity, ability to homodimerize extracellular domains (ECDs) of several lactogenic and somatogenic receptors, and by in vitro bioassays. Two analogues were prepared in large amounts for in vivo studies. These studies (a) identified the residues responsible for the somatogenic activity of

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Wu, Xiaoqi, Maoxia Fan, Yaobo Pan, and Dona Guo. Quality of Evidence Supporting the Effects of Ginkgo Terpene Lactone Preparations in Ischemic Stroke: An Overview of Systematic Reviews and Meta-Analyses. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.9.0124.

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Review question / Objective: 2.2.1 Type of studies SRs/MAs of Randomized Controlled Trials (RCTs) of GTLP for IS in any language. 2.2.2 Type of Participants Included patients were diagnosed with IS according to international or national standards, regardless of race, age, gender, time of onset, and source of cases. 2.2.3 Type of Intervention The intervention method in the control group was routine treatment, and the intervention method in the intervention group was GTLP treatment or GTLP combined with the treatment of the control group. 2.2.4 Types of outcomes Conclusions at least need to incl

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