Academic literature on the topic 'Limonoids'

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Journal articles on the topic "Limonoids"

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Minamisawa, Mayumi, Takuma Suzumura, Sudeep Bose, et al. "Effect of Yuzu (Citrus junos) Seed Limonoids and Spermine on Intestinal Microbiota and Hypothalamic Tissue in the Sandhoff Disease Mouse Model." Medical Sciences 9, no. 1 (2021): 17. http://dx.doi.org/10.3390/medsci9010017.

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The effect of limonoids and spermine (Spm) extracted from yuzu (Citrus junos) seeds on the gut and the brain in a mouse model with Sandhoff disease (SD) was investigated. Wild-type and SD mice were fed a normal diet, or a diet supplemented with limonoid, Spm, or limonoid + Spm for 14–18 weeks, and then 16S rRNA gene amplicon sequencing with extracted DNA from their feces was executed. For SD control mice, intestinal microbiota was mostly composed of Lactobacillus and linked to dysbiosis. For SD and wild-type mice fed with limonoids + Spm or limonoids alone, intestinal microbiota was rich in mu
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Laphookhieo, Surat, Wisanu Maneerat, Sorwaporn Koysomboon, Rattana Kiattansakul, Kan Chantrapromma, and John Keith Syers. "A novel limonoid from the seeds of Chisocheton siamensis." Canadian Journal of Chemistry 86, no. 3 (2008): 205–8. http://dx.doi.org/10.1139/v07-155.

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Analysis of an acetone/hexane (1:1) extract of the seeds of Chisocheton siamensis led to the isolation of a novel limonoid, chisosiamensin (1), along with five known limonoids, dysobinin (2), azadiradione (3), mohinin (4), epoxyazadiradione (5), and 6α-acetoxyepoxyazadiradione (6). Their structures were characterized by spectroscopic methods, including UV, IR, NMR, and MS. All isolated limonoids were reported for the first time as secondary metabolites of C. siamensis.Key words: Chisocheton siamensis, Meliaceae, chisosiamensin, limonoids.
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Hodgson, Hannah, Ricardo De La Peña, Michael J. Stephenson, et al. "Identification of key enzymes responsible for protolimonoid biosynthesis in plants: Opening the door to azadirachtin production." Proceedings of the National Academy of Sciences 116, no. 34 (2019): 17096–104. http://dx.doi.org/10.1073/pnas.1906083116.

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Limonoids are natural products made by plants belonging to the Meliaceae (Mahogany) and Rutaceae (Citrus) families. They are well known for their insecticidal activity, contribution to bitterness in citrus fruits, and potential pharmaceutical properties. The best known limonoid insecticide is azadirachtin, produced by the neem tree (Azadirachta indica). Despite intensive investigation of limonoids over the last half century, the route of limonoid biosynthesis remains unknown. Limonoids are classified as tetranortriterpenes because the prototypical 26-carbon limonoid scaffold is postulated to b
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Liu, Shengyu, Linping Hu, Dong Jiang, and Wanpeng Xi. "Effect of Post-Harvest LED and UV Light Irradiation on the Accumulation of Flavonoids and Limonoids in the Segments of Newhall Navel Oranges (Citrus sinensis Osbeck)." Molecules 24, no. 9 (2019): 1755. http://dx.doi.org/10.3390/molecules24091755.

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To investigate the effect of post-harvest light irradiation on the accumulation of flavonoids and limonoids, harvested Newhall navel oranges were continuously exposed to light-emitting diode (LED) and ultraviolet (UV) light irradiation for 6 days, and the composition and content of flavonoids and limonoids in the segments were determined using UPLC-qTOF-MS at 0, 6, and 15 days after harvest. In total, six polymethoxylated flavonoids (PMFs), five flavone-O/C-glycosides, seven flavanone-O-glycosides, and three limonoids were identified in the segments. The accumulation of these components was al
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Amuti, Saidanxia, Yohei Saito, Shuichi Fukuyoshi, et al. "Unusual Vilasinin-Class Limonoids from Trichilia rubescens." Molecules 29, no. 3 (2024): 651. http://dx.doi.org/10.3390/molecules29030651.

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Eight vilasinin-class limonoids, including the unusually chlorinated rubescins K–M (1–3), the 2,3-epoxylated rubescin N (4), and rubescins O–R (5–8), were newly isolated from Trichilia rubescens. The structures of the isolated compounds were determined through spectroscopic and spectrometric analyses, as well as ECD calculations. The natural occurrence of chlorinated limonoids 1–3 was confirmed by chemical methods and HPLC analysis of a roughly fractionated portion of the plant extract. Eight selected limonoids, including previously known and new compounds, were evaluated for antiproliferative
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De La Peña, Ricardo, Hannah Hodgson, Jack Chun-Ting Liu, et al. "Complex scaffold remodeling in plant triterpene biosynthesis." Science 379, no. 6630 (2023): 361–68. http://dx.doi.org/10.1126/science.adf1017.

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Triterpenes with complex scaffold modifications are widespread in the plant kingdom. Limonoids are an exemplary family that are responsible for the bitter taste in citrus (e.g., limonin) and the active constituents of neem oil, a widely used bioinsecticide (e.g., azadirachtin). Despite the commercial value of limonoids, a complete biosynthetic route has not been described. We report the discovery of 22 enzymes, including a pair of neofunctionalized sterol isomerases, that catalyze 12 distinct reactions in the total biosynthesis of kihadalactone A and azadirone, products that bear the signature
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Fu, Shaomin, and Bo Liu. "Recent progress in the synthesis of limonoids and limonoid-like natural products." Organic Chemistry Frontiers 7, no. 14 (2020): 1903–47. http://dx.doi.org/10.1039/d0qo00203h.

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Recent progress in syntheses of limonoids and limonoid-like natural products is reviewed. The current “state-of-art” advance on novel synthetic strategy are summarized and future outlook will be presented.
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Jogia, Madhu K., and Raymond J. Andersen. "Limonoids from the Fijian medicinal plant Dysoxylumrichii." Canadian Journal of Chemistry 67, no. 2 (1989): 257–60. http://dx.doi.org/10.1139/v89-042.

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Three new limonoids have been isolated from the Fijian medicinal plant Dysoxylumrichii. Dried D. richii leaves collected at Suva yielded the known limonoid dysoxylin (1) as well as the previously unreported dysoxylone (2). A Taveuni collection of leaves contained the two new metabolites tigloyldysoxylin (3) and 6α-acetoxyobacunol acetate (4). The structures of all three new compounds were determined by spectroscopic analysis. Keywords: Dysoxylumrichii, limonoid, dysoxylone, tigloyldysoxylin, 6α-acetoxyobacunol acetate.
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Dandekar, Deepak V., Guddadarangavvanahally K. Jayaprakasha, and Bhimanagouda S. Patil. "Simultaneous Extraction of Bioactive Limonoid Aglycones and Glucoside from Citrus aurantium L. Using Hydrotropy." Zeitschrift für Naturforschung C 63, no. 3-4 (2008): 176–80. http://dx.doi.org/10.1515/znc-2008-3-403.

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Citrus limonoids were demonstrated to possess potential biological activities in reducing the risk of certain diseases. Limonoids are present in citrus fruits in the form of aglycones and glucosides. At present, limonoid aglycones and limonoid glucosides are extracted in multiple steps using different solvents. In order to understand their potential bioactivity, it may be beneficial to isolate and purify these compounds using environment friendly methods. A new method of extraction and purification of limonoids was established using a hydrotrope polystyrene adsorbent resin. Extraction of aglyc
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Oliveira, Iara dos Santos da Silva, Carla Junqueira Moragas Tellis, Maria do Socorro dos Santos Chagas, et al. "Carapa guianensis Aublet (Andiroba) Seed Oil: Chemical Composition and Antileishmanial Activity of Limonoid-Rich Fractions." BioMed Research International 2018 (September 6, 2018): 1–10. http://dx.doi.org/10.1155/2018/5032816.

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Leishmaniasis is a complex of diseases caused by protozoa of the genus Leishmania and affects millions of people around the world. Several species of plants are used by traditional communities for the treatment of this disease, among which is Carapa guianensis Aubl. (Meliaceae), popularly known as andiroba. The objective of the present work was to conduct a chemical study of C. guianensis seed oil and its limonoid-rich fractions, with the aim of identifying its secondary metabolites, particularly the limonoids, in addition to investigating its anti-Leishmania potential. The chemical analyses o
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Dissertations / Theses on the topic "Limonoids"

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Rizza, Giorgio. "Citrus Limonoids: Functional Chemicals in Agriculture and Foods." Doctoral thesis, Università di Catania, 2016. http://hdl.handle.net/10761/4026.

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The search for limonoids started long back when scientists started looking for the factor responsible for bitterness in citrus. Studies showed that limonoids are highly oxygenated, modified terpenoids and have recently attracted attention because compounds belonging to this group have exhibited a range of biological activities like insecticidal, insect antifeedant and growth regulating activity on insects as well as antibacterial, antifungal, antimalarial, anticancer, antiviral and a number of other pharmacological activities on humans. Based on this premise this paper has focused on technol
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Haldar, S. "Chemical finger-printing, metabolic profiling, and biotransformation of neem (Azadirachta Indica) limonoids." Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 2014. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/1971.

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Poulose, Shibu M. "Isolation and effects of citrus limonoids on cytochrome p450 inhibition, apoptotic induction and cytotoxicity on human cancer cells." Texas A&M University, 2005. http://hdl.handle.net/1969.1/4946.

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This dissertation illustrates an efficient purification method for citrus limonoids and flavonoids, while examining their effects on cytochrome P450 inhibition and apoptotic induction on human neuroblastoma (SH-SY5Y) and colonic adenocarcinoma (Caco-2) cells. The first study developed a bulk purification method for limonoids, from seeds and molasses of citrus fruits, using a combination of chromatographic techniques. This also resulted in an efficient purification method for naringin and hesperidin from citrus byproducts. The second study investigated the inhibitory effects of purified limonoi
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Yu, Jun. "Citrus limonoids and flavonoids: extraction, antioxidant activity and effects on hamster plasma cholesterol distribution." Texas A&M University, 2004. http://hdl.handle.net/1969.1/2772.

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Four in vitro models were used to measure the antioxidant activity of 11 citrus phytochemicals. The citrus limonoids and bergapten showed very weak antioxidant activity. The flavonoids demonstrated mild, to moderate, to strong antioxidant activity. In addition to some other commonly accepted structural features our data indicated that the hydroxyl group in position 6 of ring A could also increase the antioxidant activity of flavonoids. Compared with the active flavonoids, limonoids are highly oxygenated triterpenoids, with fewer hydroxyl groups to stabilize unpaired electrons (or scavenge free
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SUCAMELI, MARZIA. "Antioxidant and Antiviral potential against SARS-CoV-2 of citrus limonoids isolated from Grapefruit Seed Extracts." Doctoral thesis, Università degli studi di Genova, 2021. http://hdl.handle.net/11567/1057597.

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The COVID-19 pandemic represented an unprecedented global emergency. Despite all efforts, COVID-19 remains a threat to public health, due to the complexity of mass vaccination programs, the lack of effective drugs, and the emergence of new variants. A link has recently been found between the risk of developing a severe COVID-19 infection and a high level of oxidative stress. In this context, we have focused our attention on natural compounds with the aim of finding molecules capable of acting through a dual antiviral / antioxidant mechanisms. In particular, we studied the potential of grapefru
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Dai, Jianming. "Microwave-assisted extraction (MAE) of neem and the development of a colorimetric method for the determination of azadirachtin related limonoids (AZRL)." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape3/PQDD_0035/MQ64339.pdf.

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Garcez, Fernanda Rodrigues. "Limonóides e protolimonóides de Trichilia elegans ssp. Elegans A. Juss. (Meliaceae)." Universidade de São Paulo, 1997. http://www.teses.usp.br/teses/disponiveis/46/46135/tde-12112015-153501/.

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o presente trabalho teve como objetivo realizar o estudo químico das sementes de Trichilia elegans ssp. Elegans A. Juss. (coletadas no município de Corumbá, MS), visando o isolamento e identificação ou elucidação estrutural dos seus metabólitos secundários, particularmente limonóides. Da fase diclorometânica, obtida de uma partição efetuada com o extrato etanólico das sementes, foram isoladas, através de técnicas cromatográficas de separação (cromatografia em colunas de sílica gel, de Sephadex LH 20 e CLAE em fase reversa), dezoito substâncias, compreendendo: dois protolimonóides, onze limonói
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Craig, D. "Studies towards limonoid insect antifeedant synthesis." Thesis, Imperial College London, 1986. http://hdl.handle.net/10044/1/37980.

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AID, LYDIA. "Vers la synthese totale d'un limonoide, l'haperforine b1." Paris 11, 2000. http://www.theses.fr/2000PA112206.

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L'objectif de ce travail etait de realiser la synthese d'un precurseur de l'haperforine b 1, limonoide extrait de feuilles d'harrisonia perforata recoltees dans le centre du viet-nam et utilisees en medecine traditionnelle contre la gale. La cible visee correspond a un cyclohexane comportant quatre centres asymetriques adjacents dont trois sont quaternaires. La strategie adoptee consiste en une reaction de diels-alder intermoleculaire entre un butenolide active par un groupe carbomethoxy et un butadiene substitue en position terminale par un groupement acetoxy. Le resultat de la reaction est u
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Santafianos, Dinos. "Studies on the potent limonoid insect antifeedant azadirachtin." Thesis, Imperial College London, 1987. http://hdl.handle.net/10044/1/46471.

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Books on the topic "Limonoids"

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Berhow, Mark A., Shin Hasegawa, and Gary D. Manners, eds. Citrus Limonoids. American Chemical Society, 2000. http://dx.doi.org/10.1021/bk-2000-0758.

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1954-, Berhow Mark A., Hasegawa Shin 1932-, Manners Gary D. 1934-, and American Chemical Society. Meeting (1999 : Anaheim, Calif.), eds. Citrus limonoids: Functional chemicals in agriculture and food. American Chemical Society, 2000.

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Ryan-Hayes, Karen L. Limonov's It's me, Eddie and the autobiographical mode. University of Pittsburgh, Center for Russian and East European Studies, 1993.

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Ryan, Karen L. Limonov's It's me, Eddie and the autobiographical mode: Karen Ryan-Hayes. REES, Center for Russian & East European Studies, University of Pittsburgh, 1993.

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Ryan-Hayes, Karen L. Limonov's It's me, Eddie and the autobiographical mode: Karen Ryan-Hayes. REES, Center for Russian & East European Studies, University of Pittsburgh, 1993.

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(Editor), Mark A. Berhow, Shin Hasegawa (Editor), and Gary D. Manners (Editor), eds. Citrus Limonoids: Functional Chemicals in Agriculture and Food (Acs Symposium Series). An American Chemical Society Publication, 2000.

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Wagner, Sebastian. Tabuisierte Sprachvarietaeten Im Russischen und Ihre Uebersetzung Ins Deutsche: Ein Theoretischer Abriss und Uebersetzung Ausgewaehlter Textpassagen Aus Ėduard V. Limonovs Werk «Ėto Ja - Ėdička» Ins Deutsche. Lang GmbH, Internationaler Verlag der Wissenschaften, Peter, 2016.

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Wagner, Sebastian. Tabuisierte Sprachvarietaeten Im Russischen und Ihre Uebersetzung Ins Deutsche: Ein Theoretischer Abriss und Uebersetzung Ausgewaehlter Textpassagen Aus Ėduard V. Limonovs Werk «Ėto Ja - Ėdička» Ins Deutsche. Lang GmbH, Internationaler Verlag der Wissenschaften, Peter, 2016.

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Wagner, Sebastian. Tabuisierte Sprachvarietaeten Im Russischen und Ihre Uebersetzung Ins Deutsche: Ein Theoretischer Abriss und Uebersetzung Ausgewaehlter Textpassagen Aus Ėduard V. Limonovs Werk «Ėto Ja - Ėdička» Ins Deutsche. Lang GmbH, Internationaler Verlag der Wissenschaften, Peter, 2016.

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Wagner, Sebastian. Tabuisierte Sprachvarietaeten Im Russischen und Ihre Uebersetzung Ins Deutsche: Ein Theoretischer Abriss und Uebersetzung Ausgewaehlter Textpassagen Aus Ėduard V. Limonovs Werk «Ėto Ja - Ėdička» Ins Deutsche. Lang GmbH, Internationaler Verlag der Wissenschaften, Peter, 2016.

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Book chapters on the topic "Limonoids"

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Hasegawa, Shin, Chi H. Fong, Zareb Herman, and Masaki Miyake. "Glucosides of Limonoids." In ACS Symposium Series. American Chemical Society, 1992. http://dx.doi.org/10.1021/bk-1992-0490.ch008.

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Hasegawa, Shin. "Biochemistry of Limonoids inCitrus." In ACS Symposium Series. American Chemical Society, 2000. http://dx.doi.org/10.1021/bk-2000-0758.ch002.

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Seigler, David S. "Limonoids, Quassinoids, and Related Compounds." In Plant Secondary Metabolism. Springer US, 1998. http://dx.doi.org/10.1007/978-1-4615-4913-0_25.

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Cheng, Yongxian, and Dapeng Qin. "Classification of Diverse Novel Limonoids." In Novel Plant Natural Product Skeletons. Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-99-7329-3_6.

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Hasegawa, Shin, and Zareb Herman. "Biosynthesis of Limonoids in Citrus." In Secondary-Metabolite Biosynthesis and Metabolism. Springer US, 1992. http://dx.doi.org/10.1007/978-1-4615-3012-1_21.

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Herman, Z., C. H. Fong, and S. Hasegawa. "Analysis of Limonoids in Citrus Seeds." In Modern Methods of Plant Analysis. Springer Berlin Heidelberg, 1992. http://dx.doi.org/10.1007/978-3-662-01639-8_19.

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Kim, Jinhee, G. K. Jayaprakasha, Amit Vikram, and Bhimanagouda S. Patil. "Cancer Chemopreventive Properties of Citrus Limonoids." In ACS Symposium Series. American Chemical Society, 2012. http://dx.doi.org/10.1021/bk-2012-1093.ch003.

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Hasegawa, Shin, and Mark Berhow. "Analysis of Limonoids by Thin-Layer Chromatography." In ACS Symposium Series. American Chemical Society, 2000. http://dx.doi.org/10.1021/bk-2000-0758.ch003.

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Miller, E. G., S. E. Taylor, C. W. Berry, J. A. Zimmerman, and Shin Hasegawa. "Citrus Limonoids: Increasing Importance as Anticancer Agents." In ACS Symposium Series. American Chemical Society, 2000. http://dx.doi.org/10.1021/bk-2000-0758.ch010.

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Jayaprakasha, Guddadarangavvanahally K., Jennifer S. Brodbelt, Narayan G. Bhat, and Bhimanagouda S. Patil. "Methods for the Separation of Limonoids from Citrus." In ACS Symposium Series. American Chemical Society, 2006. http://dx.doi.org/10.1021/bk-2006-0936.ch003.

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Conference papers on the topic "Limonoids"

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Becceneri, Amanda Blanque, Angelina Maria Fuzer, Julio Cesar Conceição Filho, et al. "Abstract B10: Effects of limonoid cedrelone on MDA-MB-231 breast tumor cells in vitro." In Abstracts: Third AACR International Conference on Frontiers in Basic Cancer Research - September 18-22, 2013; National Harbor, MD. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.fbcr13-b10.

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Gladcaia, Alla, and Tudor Nastas. "Plant extracts in spider mites control." In Scientific International Symposium “Advanced Biotechnologies - Achievements and Prospects” (VIth Edition). Institute of Genetics, Physiology and Plant Protection, 2022. http://dx.doi.org/10.53040/abap6.2022.55.

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The use of plant secondary metabolites synthesized by some plant species as part of their natural self-defense against pathogens and pests seems to be an excellent alternative biopestici-des are more and more popular with food manufacturers and consumers equally. Biopesticides could grow from 4–5% of the global pesticide market to as much as 20% by 2025 [1]. The important bioactive compounds of neem seed oil belong to the limonoid class of triterpenoids, such as azadirachtin, nimbin [2]. Extracts of rhubarb roots and leaves are a source of various biologically active substances such as emodin,
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Reports on the topic "Limonoids"

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Vandenberg, Ted. Inhibition of Mammary Cancer by Citrus Limonoids. Defense Technical Information Center, 2001. http://dx.doi.org/10.21236/ada398201.

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Vandenberg, Ted. Inhibition of Mammary Cancer by Citrus Limonoids. Defense Technical Information Center, 1999. http://dx.doi.org/10.21236/ada383033.

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