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1

B., A. Eke, A. Ojo B., D. Akaa P., N. Ahachi C., Soo C., and Adekwu A. "The Spectrum of Breast Diseases in Nigeria North Central: A Histopathological Survey." Journal of Advances in Medical and Pharmaceutical Sciences 13, no. 3 (2017): 1–6. https://doi.org/10.9734/JAMPS/2017/32384.

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Breast diseases to most patients are sources of uncertainty and apprehension. The diseases of the breast are a heterogeneous group of lesions consisting of both benign and malignant. This study from North Central Nigeria is aimed at examining these diverse lesions. 249 breast biopsies with histopathological diagnosis seen at Benue State University Teaching Hospital, Makurdi, Nigeria between October, 2012 and January 2017 were examined. The cases were retrieved from the data base of the histopathology department with the patients request forms. The patient’s bio data was extracted from the requ
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AHMED SHAIKH, NASEER, IKRAM-UD DIN UJJHN, FARZANA CHANG, and Jawaid Aqeel Rajput. "BREAST DISEASES;." Professional Medical Journal 19, no. 03 (2012): 356–59. http://dx.doi.org/10.29309/tpmj/2012.19.03.2140.

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Breast lump is the common complaint of women in clinics, which includes the second leading cause of cancer deaths in women.Objective: The study was conducted to know the pattern of female breast diseases in our setup at Hyderabad / Jamshoro. Design: Adescriptive Study. Setting: Liaquat University of Medical and Health Sciences, Jamshoro. Material & Methods: Descriptive study Setting: Itwas conducted in the department of pathology, Liaquat University of Medical and Health Sciences, Jamshoro. Period: Ten years from January2001 to December 2010. Results: Total of 2693 breast biopsies and mast
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Bajracharya, Amir, and Anang Pangeni. "Profile of Breast Diseases in Eastern Nepal." Journal of College of Medical Sciences-Nepal 12, no. 3 (2016): 89–93. http://dx.doi.org/10.3126/jcmsn.v12i3.15090.

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Background & Objectives: Breast problems, benign or malignant are common in occurrence worldwide. Breast problems can present themselves in a number of ways like breast pain, nipple discharge, cystic lesions and more commonly a lump. Breast diseases are under reported and cancer is one of the leading causes of mortality in women. This prospective study was undertaken with an aim to study the profile of various breast diseases in eastern Nepal.Materials & Methods: This is a prospective study of women with breast diseases conducted from March 2011 to February 2012. Inclusion criteria wer
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Yousif, Zena Habeeb, and Selwa Elias Yacoub. "Patterns of Breast Diseases Among Women Attending Breast Diseases Diagnosing Center in Erbil City/Iraq." Global Journal of Health Science 10, no. 4 (2018): 114. http://dx.doi.org/10.5539/gjhs.v10n4p114.

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BACKGROUND & OBJECTIVES: Breast diseases in women, whether benign or malignant, are very commonly encountered. The pattern of breast diseases varies within countries. The aim of this study was to identify the patterns of breast diseases and their association with different variables in women attending breast diseases diagnosing center in Erbil city/Iraq.MATERIAL & METHODS: A cross-sectional study conducted at breast diseases diagnosing center in Erbil city from 1st of April till 1st of December /2017. A random sample of 500 women of all age groups and with complete records was recruite
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ZAFAR, AFSHEEN, and AHMED REHMAN. "BREAST DISEASES;." Professional Medical Journal 20, no. 03 (2013): 450–55. http://dx.doi.org/10.29309/tpmj/2013.20.03.905.

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Objective: To determine pattern of breast diseases presenting in the surgical OPD of a General hospital. Design: Aprospective observational study. Place & duration of study: The study was conducted at Railway hospital, Rawalpindi from September2008 to Feburary 2010. Patients & Methods: Female patients presenting with complaints regarding breast were recruited in the study. Allof them underwent clinical breast examination followed by necessary radiological and / or histopathological investigations to diagnosethe disease. Data regarding personal information, clinical examination findings
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6

Autenschlyus, A. I., A. V. Bernado, K. I. Davletova, et al. "Proteins and immunohistochemical markers of breast diseases." Biomeditsinskaya Khimiya 66, no. 2 (2020): 167–73. http://dx.doi.org/10.18097/pbmc20206602167.

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In this work, we have compared malignant and non-malignant diseases of the mammary gland using 8 proteins: HRG, MUC1, PAI-1, HSP90αA1, CDH1, ERα, PGR and IL-12. Their concentrations in the supernatants of blood cells and breast biopsies were compared in terms of spontaneous production, induced by a polyclonal activator and after exposure to biopsy samples of the HLDF differentiation factor, as well as the indices of the effect of the polyclonal activator and HLDF on the protein production. In addition, the correlation relationships of the above indicators with the expression of markers of the
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7

Alvarez, A., P. I. Martinez Rodriguez, M. I. Nuñez, A. Alba, M. T. Allende, and A. Ruibal Morell. "TPS cytosolic levels in non-malignant breast diseases." International Journal of Biological Markers 10, no. 3 (1995): 183–85. http://dx.doi.org/10.1177/172460089501000311.

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8

Strauss, A. "Malignant breast diseases as differential diagnoses in mastitis." Senologie - Zeitschrift für Mammadiagnostik und -therapie 13, no. 02 (2016): 69–75. http://dx.doi.org/10.1055/s-0042-106077.

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9

Yalagachin, Gurushantappa, Nishanth Lakshmikantha, and Sanjay B. Mashal. "Prevalence of nodular goiter in patients with breast diseases." Journal of Clinical and Investigative Surgery 5, no. 2 (2020): 91–95. http://dx.doi.org/10.25083/2559.5555/5.2/91.95.

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Introduction. Various studies have reported conflicting results regarding the relationship between breast and thyroid diseases. The exact pathogenesis behind this association is not clear. The aim of this study was to determine the prevalence of thyroid disease in patients presenting with breast diseases and to examine whether thyroid screening is required in patients with breast diseases. Methodology. All patients attending the department of General Surgery in our institution with breast diseases during the period from December 2015 to September 2017 were enrolled for the study. A thorough cl
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10

Patel, Pinakin, Naina Kumar, Kriti Gera, et al. "Spectrum of breast diseases in North Western India: an analysis of 8604 pathologies." International Surgery Journal 10, no. 3 (2023): 426–31. http://dx.doi.org/10.18203/2349-2902.isj20230495.

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Background: There is paucity of data on the spectrum of breast diseases in India due to lack of reporting system. This study was conducted to understand the pattern of breast diseases in northwest India. It is by far the largest study to provide epidemiological data on breast disease spectrum in India. Methods: Total of 8604 breast pathological reports were obtained from four major diagnostic centers in North West India. These included benign and malignant breast lesions. Results: There were 5985 (69.56%) lesions in the benign group and 2619 (30.43%) lesions in malignant group. Women formed 92
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Ahmed, Shakera, Sami Ahmad, Nadim Ahmed, and Nur Mohommad Sayed Bin Aziz. "Spectrum of Breast Diseases in Females- a 10 years study." Journal of Shaheed Suhrawardy Medical College 9, no. 1 (2018): 10–12. http://dx.doi.org/10.3329/jssmc.v9i1.37252.

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Objective: To determine the frequency of various breast diseases in female patients.Methodology: This is a prospective (historical)cohort study of female patients from 18 to 55 years of age visiting a female surgeon with breast problems. The study was conducted at Chittagong Metropoliton Hospital and CSCR Hospital in Chittagong over a period of 10 years starting from July 2007 to June 2017. All female patients visiting with breast problems were included in the study, excluding the patients of below 18 years and above 55 years. The findings were tabulated in excel sheet and analyzed for the fre
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Abd Elhamied, Hany Mahmoud. "Forms of Breast Disorders within Females Visiting Breast Disease Clinic." Women Health Care and Issues 5, no. 6 (2022): 01–05. http://dx.doi.org/10.31579/2642-9756/174.

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1.1. Background: Breast disorders, either benign or malignant in nature, are clinically common. The forms of breast disorders vary within different nations. 1.2. Objectives: The goal of the current research study is to explore and observe the forms of breast disease and their correlation with various obtained variables of interest in females visiting the breast disease clinic. 1.3. Methodology: A cross-sectional research study performed at El Sahel Teaching Hospital from 1st of May 2017 till 1st of February 2017. A randomly selected cohort of 500 research subjects of all age categories have be
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13

Abdul Wahhab, Rawaa Abdul Sattar, Luma Kareem Mohammed, and Bashar Abbas Abdulhassan. "Clinical Profile of Female Patients Presented with Breast Diseases: An Institutional Analysis in Baghdad, Iraq." Al-Rafidain Journal of Medical Sciences ( ISSN 2789-3219 ) 8, no. 1 (2025): 23–26. https://doi.org/10.54133/ajms.v8i1.1597.

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Background: Female patients may complain of breast symptoms throughout their lives. These lesions are mostly benign. Benign breast lesions are much more common than breast cancer throughout the world. Objectives: to assess the frequency, pattern, and clinical presentation of breast diseases among female patients attending the breast clinic in one of the largest teaching hospitals in Baghdad, Iraq, during 2023. Methods: All cases that visited the breast clinic at Al-Imamein Al-Kadhmain Medical City Hospital, Iraq, in 2023 had their case files reviewed as part of a cross-sectional descriptive su
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14

Javaid Butt, Maliha, Usman Ali Rahman, Iftikhar Ahmed, Ch Muhammad Atif Niaz, Muhammad Adil Iftikhar, and Humaira Yousaf. "A Comparison of Fine Needle Aspiration Cytology (FNAC) with Tru-cut Biopsy in Breast Lump Patients Taking Histopathology as Gold Standard." Esculapio 19, no. 3 (2023): 342–45. http://dx.doi.org/10.51273/esc23.251319317.

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Objective: To compare sensitivity and specificity of FNAC with Tru-cut biopsy diagnosis of breast lump patients. Material and Methods: It was a cross sectional study conducted at surgical department of Gulab Devi Teaching Hospital Lahore from January 2022 to December 2022. Atotal of 122 patients presented in surgical OPD with complaints of breast lump of size between 2cm to 4 cm were included in the study with their consent. All these patients underwent FNAC, true cut biopsy and excisional biopsy. Sensitivity and specificity of both FNAC and true cut were calculated. Results: Mean age of patie
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15

Donohue, John H. "The Breast: Comprehensive Management of Benign and Malignant Diseases." Mayo Clinic Proceedings 67, no. 12 (1992): 1212. http://dx.doi.org/10.1016/s0025-6196(12)61158-6.

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16

Ellis, I. O. "The Breast; comprehensive management of benign and malignant diseases." Breast 2, no. 2 (1993): 122. http://dx.doi.org/10.1016/0960-9776(93)90173-d.

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17

Abel, W. G. "The Breast: Comprehensive Management of Benign and Malignant Diseases." JAMA: The Journal of the American Medical Association 266, no. 6 (1991): 853. http://dx.doi.org/10.1001/jama.1991.03470060115045.

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18

Selvakumaran, S., and Mimamaychet B. Sangma. "Study of various benign breast diseases." International Surgery Journal 4, no. 1 (2016): 339. http://dx.doi.org/10.18203/2349-2902.isj20164466.

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Background:Benign breast disorders can be defined as any non-malignant breast condition and encompasses a wide range of clinical and pathological disorders. BBD are very common and 1/3rd of women are suffering from this disorder in one time of their life. The aim of this study is to look at the patterns of benign breast diseases, the mode of presentation, management and to identify risk factors.Methods: This descriptive study was done in 168 patients presented to the surgery OPD department with benign breast disorders. All the patients with breast related disease were included in this study. B
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19

Devkota, Harihar, Suryaman Menyangbo, and Kapil Amgain. "Spectrum of breast diseases in a rural himalayan region of Western Nepal: a hospital based study." Journal of Chitwan Medical College 10, no. 3 (2020): 95–97. http://dx.doi.org/10.3126/jcmc.v10i3.32062.

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Background: Breast diseases, among the most common diseases in females occur in various pat­terns from benign to malignant. Their identification is crucial as some of the benign disorders pose threat to turn into malignancy. This study was aimed to determine the spectrum of breast diseases.
 Methods: This was a hospital based retrospective study among all the patients in General Surgery OPD of Karnali Academy of Health Sciences, Teaching Hospital, diagnosed with breast diseases during one year period from August 2019 to July 2020 AD. Data were extracted and entered in SPSS version 16 for
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20

Vуsotskaya, I. V., I. A. Gladilina, V. Yu Kirsanov, N. V. Ponedelnikova, E. A. Kim, and V. E. Ponomarev. "Lesions of the breast with uncertain malignant potential." Tumors of female reproductive system 17, no. 2 (2021): 46–57. http://dx.doi.org/10.17650/1994-4098-2021-17-2-46-57.

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The article deals with a peculiar group of breast diseases, which belongs to the B3 category according to the BI-RADS classification, the so-called lesions with undefined malignant potential. The basic information concerning their biological behavior and modern tactical approaches to the management of patients with similar changes in the mammary gland are presented. The possibility of conservative management, as well as the minimization of surgical aid, in cases of indications for it, up to vacuum aspiration biopsy is being considered. In addition, the significance of these diseases for the su
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21

Sosnowska-Sienkiewicz, Patrycja, and Przemysław Mańkowski. "Clinically Malignant Breast Lesion in an Adolescent Girl: A Case Report." Clinics and Practice 11, no. 3 (2021): 435–40. http://dx.doi.org/10.3390/clinpract11030058.

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Diseases of the breast in adolescent women are usually benign, and their treatment is simple using appropriate medical strategy and rarely surgical therapy. The whole team’s real challenge is when the girl presents malignant breast cancer symptoms such as a non-movable tumor, nipple discharge, nipple retraction, retraction of the skin, inflammatory infiltration of the breast, or ulceration. Presented here is a case of a 15-years-old girl with the features of a malignant neoplasm of the breast. There was an observed non-movable tumor, retraction of the nipple, inflammatory infiltration, and pai
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Chandak, S. R., and Md Omar Tabrez. "A study on clinical profile and management of lump in breast at tertiary rural hospital, Wardha, Maharashtra, India." International Surgery Journal 4, no. 3 (2017): 998. http://dx.doi.org/10.18203/2349-2902.isj20170850.

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Background: Breast lumps diseases are one of the most common diseases in India which include congenital, traumatic, inflammatory, hormonal mastopathy, benign and malignant neoplastic conditions. Around 200,000 cases of breast diseases are diagnosed annually. In India, as there is no study of breast disease conducted separately in rural India hence studies are required to evaluate the incidence and prevalence of breast lump diseases so that interventions can be done to educate and guide people about the risk factors, importance of screening and management strategies.Methods: We have conducted o
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Tari, Daniele Ugo, and Fabio Pinto. "Mammography in Breast Disease Screening and Diagnosis." Journal of Personalized Medicine 13, no. 2 (2023): 228. http://dx.doi.org/10.3390/jpm13020228.

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24

Chavan, Ramesh, and Anil Prasad. "Clinicopathological study of breast diseases: A hospital-based study." Journal of Pathology of Nepal 9, no. 1 (2019): 1460–63. http://dx.doi.org/10.3126/jpn.v9i1.21991.

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Background: Breast diseases are more common in women than men. Breasts undergo perpetual physical and physiological transition from puberty till death, which are related to menstruation, pregnancy, and menopause. The aim of this was to classify different types of the breast lesions, and conduct its clinicopathological study.
 Materials and Methods: Breast lesion tissue specimens were collected either as needle biopsy, lumpectomy, or mastectomy. For specimens fixation, 10% formal saline was used. Tissue was processed into paraffin blocks and stained using hematoxylin and eosin. Data were e
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Kiran, Nazma, Nausheen Henna, Ayesha Gohier, Nadia Aslam, Muhammad Faisal Javaid, and Naveed Akhter. "Spectrum of Benign Breast Diseases in Surgically Excised Specimens: A Clinicopathological Study." Pakistan Journal of Medical and Health Sciences 16, no. 6 (2022): 59–61. http://dx.doi.org/10.53350/pjmhs2216659.

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Background: Approximately 30% of female population suffers from benign breast diseases in anytime of their life. A comprehensive review of histopathological findings can tell us the behavior and type of the breast lesion and will also benefit the patient and the clinician to take the timely decision. Aim: To understand the histopathological pattern of benign breast diseases encountered in RMC teaching hospital, Sargodha. Methods: This descriptive study was undertaken in the Pathology Department, Rai Medical College, Sargodha, from January 2017 to December 2021. 146 breast lump specimens were i
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Garcia-F-Villalta, MJ, M. Adrados, E. Dauden, J. Fraga, and A. Garcia-Diez. "Pigmented metastasis of breast carcinoma mimicking malignant melanoma." Journal of the European Academy of Dermatology and Venereology 18, no. 2 (2004): 223–24. http://dx.doi.org/10.1111/j.1468-3083.2004.00864.x.

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27

Matsumoto, Renato Augusto Eidy Kiota, Juliana Hiraoka Catani, Mirela Liberato Campoy, Arthur Magalhães Oliveira, and Nestor de Barros. "Radiological findings of breast involvement in benign and malignant systemic diseases." Radiologia Brasileira 51, no. 5 (2018): 328–33. http://dx.doi.org/10.1590/0100-3984.2016.0125.

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Abstract Although the primary purpose of periodic mammograms in screening programs is to identify lesions suspected of being carcinomas, the findings are often related to systemic (benign or malignant) diseases, rather than breast cancer. Although the involvement of breast structures in systemic diseases is unusual, it can be included in the differential diagnosis of masses, skin changes, calcifications, asymmetry, and axillary lymphadenopathy. The main diagnostic entities that can be associated with such involvement are diabetes, chronic kidney disease, heart diseases, connective tissue disea
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Yen, Peggy P. W., Namita Sinha, Penny J. Barnes, Robinette Butt, and Sian Iles. "Benign and Malignant Male Breast Diseases: Radiologic and Pathologic Correlation." Canadian Association of Radiologists Journal 66, no. 3 (2015): 198–207. http://dx.doi.org/10.1016/j.carj.2015.01.002.

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Male breast disease comprises a wide spectrum of benign and malignant processes. We present the spectrum of diseases encountered at our institution over the past 7 years (2007-2013) and correlate their radiological and histopathological appearances. Gynaecomastia is the most frequently encountered disease due to its association with a variety of causes. Male breast malignancies, though rare, must be considered. The most frequently encountered pathological characteristic is invasive and the predominant histologic subtypes are infiltrating ductal carcinomas.
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S, Biswas. "Histopathological Characteristics of Breast Lesions in a Tertiary Health Institution in Southwest Nigeria; A 9-year Review." Journal of Surgery and Postoperative Care 1, no. 1 (2022): 01–04. http://dx.doi.org/10.58489/2836-8657/005.

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Background: The breast is affected by several diseases, including developmental, inflammatory, and neoplastic. While benign breast neoplasms are usually more common, breast cancer is the most common nonskin cancer and the leading cause of cancer-related deaths in women after lung cancer in the world. Objective: The review aimed to assess the histopathological diagnosis of breast lesions over a period of 9years Methods: This was a retrospective review of eight hundred and fourteen histopathologic cases of breast lesions accessed through laboratory records of all breast lesions cases seen. The d
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Asokan, Meena, Joseph Francis, and Bibilash Babu. "Study on Incidence of Benign Breast Diseases and Carcinomabreast in Breast Lump Cases of 200 Patients in a Tertiary Care Center in Southern Kerala." New Indian Journal of surgery 12, no. 4 (2021): 223–26. http://dx.doi.org/10.21088/nijs.0976.4747.12421.4.

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Introduction: Breast cancer accounts for about one third of female cancer. Of all lesions, benign breast diseases have been found to be commonest. The aim of study was to analyze the incidence of breast diseases over the period of 3 years and to study the spectrum of diseases and age distribution. Methods: Retrospective cross-sectional study of breast lump cases at general surgery department of Travancore medical college over a period of 3 years. Result: Of the total 200 cases up looked into, 27 out of 200 cases were found to be malignant. Fibrocystic disease was the commonest (43%), followed
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Okobia, M. N., and J. U. Aligbe. "Pattern of malignant diseases at the University of Benin Teaching Hospital." Tropical Doctor 35, no. 2 (2005): 91. http://dx.doi.org/10.1258/0049475054037147.

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This study was designed to evaluate the pattern of malignant diseases seen at the University of Benin Teaching Hospital over a 20-year period (January 1980-December 1999). A total of 2258 histologically confirmed malignant diseases were seen with the predominant tumours comprising carcinoma of the cervix (20.59%), breast (18.25%), prostate (7.13%), endometrium (6.47%) and colon and rectum (5.71%). We believe that the figure reported here represents an underestimate of the frequency of malignant tumours seen in the hospital and recommend the establishment of hospital - and population-based canc
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Rahman, Md Waliur, Imtiaz Ahmed, Shireen Jabeen Sume, Md Joynal Abedin, and Mohammad Abdul Mannan. "“A Prospective Study Clinicopathological Factors of Benign Breast Diseases”." SAS Journal of Surgery 7, no. 9 (2021): 477–81. http://dx.doi.org/10.36347/sasjs.2021.v07i09.001.

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Background: Benign breast lesions represent a wide spectrum of disorders that come to clinical attention either as palpable lumps or as imaging abnormalities. Some of these are clinically suspected as malignant lesions but diagnosed as benign after histopathological examination. Objective: To study benign breast lesions to correlate their clinicopathological parameters and to study incidence of benign breast lesions in different age groups. Materials and Methods: A descriptive study with cross sectional design was conducted in the Department of General Surgery, Chuadanga Sadar Hospital, Chuada
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O'Neill, JS, and WR Miller. "Aromatase activity in breast adipose tissue from women with benign and malignant breast diseases." British Journal of Cancer 56, no. 5 (1987): 601–4. http://dx.doi.org/10.1038/bjc.1987.248.

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Pasynkov, D. V., I. V. Klyushkin, and O. V. Busygina. "Contour analysis of mammographic images in benign and malignant breast diseases." Kazan medical journal 96, no. 3 (2015): 322–25. http://dx.doi.org/10.17750/kmj2015-322.

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Aim. Development and evaluation of the diagnostic value of techniques for quantitative analysis of masses on mammographic images satisfying the requirements of categories 2-4 in BIRADS (Breast Imaging Reporting And Data System - the system for classification and description of breast imaging results of the American College of Radiology).Methods. Images of 375 focal lesions revealed on mammography (211 malignant and 164 benign, all were verified morphologically), satisfying the criteria 2-4 according to BIRADS classification, were analyzed. Mathematical processing was performed using the MammCh
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Smagulova, G., M. Aitmagambetova, G. V. Veklenko, et al. "QUANTIFICATION OF DNA DOUBLE-STRAND BREAKS IN BENIGN AND MALIGNANT BREAST DISEASES." Oncologia i radiologia Kazakhstana 68, no. 2 (2023): 28–35. http://dx.doi.org/10.52532/2521-6414-2023-2-68-28-35.

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Relevance: Double-strand DNA breaks are the most dangerous DNA damage. Analysis of foci of phosphorylated histone protein H2AX (γH2AX) is currently the most sensitive method for detecting DNA double-strand breaks. This protein modification can become a biomarker of cellular stress, especially in diagnosing and monitoring neoplastic diseases. In this study, we utilized novel pattern recognition algorithms on the AKLIDES® platform to automatically analyze immunofluorescent images of γH2AX foci and compare the results with visual scores. The γH2AX foci formation on peripheral blood mononuclear ce
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Smagulova, G., M. Aitmagambetova, G. Veklenko, et al. "QUANTIFICATION OF DNA DOUBLE-STRAND BREAKS IN BENIGN AND MALIGNANT BREAST DISEASES." Oncologia i radiologia Kazakhstana 68, no. 2 (2023): 28–35. http://dx.doi.org/10.52532/2663-4864-2023-2-68-28-35.

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Relevance: Double-strand DNA breaks are the most dangerous DNA damage. Analysis of foci of phosphorylated histone protein H2AX (γH2AX) is currently the most sensitive method for detecting DNA double-strand breaks. This protein modification can become a biomarker of cellular stress, especially in diagnosing and monitoring neoplastic diseases. In this study, we utilized novel pattern recognition algorithms on the AKLIDES® platform to automatically analyze immunofluorescent images of γH2AX foci and compare the results with visual scores. The γH2AX foci formation on peripheral blood mononuclear ce
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A.S., Aleksandrovich, Zimatkina T.I., and Aleksandrovich I.A. "COMPRESSION ULTRASONIC ELASTOGRAPHY IN THE DIAGNOSTICS OF BENIGN AND MALIGNANT BREAST DISEASES." ИННОВАЦИОННЫЕ НАУЧНЫЕ ИССЛЕДОВАНИЯ 2023. 6-3(30) (July 9, 2023): 25–31. https://doi.org/10.5281/zenodo.8128413.

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The place of compression ultrasound elastography in the diagnosis of diseases of the breast has been determined. 122 aged women with breast pathology were examined: 38 (32 %) patients with breast cancer, 84 (68 %) women with benign pathology. Data was received indicating a high degree of correlation between the density of formation and the nature of structural changes in the breast tissue. Malignant diseases were characterized by a high degree of tissue stiffness, which was reflected in the compression elastogram in the form of mapping in blue tints. Benign tumors were mapped in green or red.
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Ge, Weiying, Xiujuan Yin, Ruxin Wang, and Jianxi Zhao. "Analysis of Clinical Diagnostic Value of Dynamic Contrast-Enhanced Magnetic Resonance Imaging Combined with MRI in Early Breast Cancer." Journal of Biomedical Nanotechnology 20, no. 1 (2024): 164–73. http://dx.doi.org/10.1166/jbn.2024.3752.

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A study involving 73 patients with early breast space-occupying diseases (41 malignant, 32 benign) utilized 1.5T quantitative dynamic enhanced magnetic resonance imaging to measure lesion-specific parameters. These included the contrast medium’s transfer rate from intravascular to extravascular (Ktrans), return rate to blood vessels (Kep), and tumor vessel volume fraction (Vp). Pathological results post-surgery served as the gold standard. Comparisons between benign and malignant groups, as well as malignant subtypes, were made. Malignant lesions exhibited varied Ktrans (0.108–2.810 min−1) and
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Naseera, Shaik, G. k. Rajini, and Saravanan M. "STATISTICAL DETECTION OF BREAST CANCER BY MAMMOGRAM IMAGE." Asian Journal of Pharmaceutical and Clinical Research 10, no. 1 (2016): 227. http://dx.doi.org/10.22159/ajpcr.2017.v10i1.15003.

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ABSTRACTObjective: To create awareness about the breast cancer which has become one of the most common diseases among women that leads to death if notrecognized at early stage.Methods: The technique of acquiring breast image is called mammography and is a diagnostic and screening tool to detect cancer. A cascade algorithmbased on these statistical parameters is implemented on these mammogram images to segregate normal, benign, and malignant diseases.Results: Statistical features - such as mean, median, standard deviation, perimeter, and skewness - were extracted from mammogram images todescrib
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Bogdanovic, Ljiljana, Slobodan Savic, and Gordana Basta-Jovanovic. "Malignant diseases as suicidal motives." Srpski arhiv za celokupno lekarstvo 135, no. 11-12 (2007): 659–65. http://dx.doi.org/10.2298/sarh0712659b.

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Introduction Suicide is a conscious and intentional destruction of one?s own life, which occurs as a result of mutual influence of a person?s disposition and motives (facts inspiring the commitment of suicide). It is well known that various diseases, including malignancies, could be important and in some cases the only motive for committing suicide. Objective The purpose of the study was to analyze in detail suicides of persons whose only motive was an established malignant disease. Method The analysis was performed using the autopsy material of the Institute of Forensic Medicine, School of Me
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Ortiz-Mendoza, Carlos, Norma Sánchez, and Arturo Dircio. "Fine-needle Aspiration Cytology to Identify a Rare Mimicker of Breast Cancer: Plasma Cell Mastitis." Revista Brasileira de Ginecologia e Obstetrícia / RBGO Gynecology and Obstetrics 40, no. 08 (2018): 491–93. http://dx.doi.org/10.1055/s-0038-1666809.

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AbstractThere are rare benign diseases that can mimic malignant breast neoplasms in the clinical exam and in mammography. We evaluated the contribution of an accessible procedure to most clinicians, the fine-needle aspiration cytology, to identify a rare mimicker of malignant breast neoplasms. A type 2 diabetic 85-year-old female presented with a 6-month history of a left breast lump. The physical exam and mammography were compatible with breast cancer. Nevertheless, after fine-needle aspiration cytology, the diagnosis was plasma cell mastitis. Once this rare diagnosis was established, the tum
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Freeman, Christopher Mark, Jaime D. Lewis, Elyse E. Lower, Shagufta Khan, and Elizabeth Shaughnessy. "Refractory granulomas of breast: Benign or malignant disease." Journal of Clinical Oncology 32, no. 26_suppl (2014): 21. http://dx.doi.org/10.1200/jco.2014.32.26_suppl.21.

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21 Background: Idiopathic granulomatous mastitis (IGM) is an uncommon benign inflammatory breast disease of unknown etiology that may mimic malignancy, infectious diseases, or autoimmune conditions requiring a diagnosis of exclusion. Because the differential diagnosis includes benign as well as malignant disease, an organized approach to the diagnosis and its symptom management is needed. Treatment may include corticosteroids, immunosuppression, or in severe refractory cases, surgery. Methods: This IRB-approved single tertiary referral center study was performed to better characterize the pres
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Ramji, Ashwath Narayan. "Clinicopathological catalogue of male breast diseases." International Surgery Journal 6, no. 5 (2019): 1756. http://dx.doi.org/10.18203/2349-2902.isj20191902.

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Background: Though relatively uncommon compared to diseases of the female breast, diseases of the male breast do occur, but are poorly studied. These range from benign lesions to malignant disease. The purpose of this study was to enumerate the various disorders of the male breast encountered in our practice, so as to develop a better understanding of the clinicopathological profile of these conditions.Methods: This was a retrospective study conducted in the Department of Surgery, KIMS Hospital, Bangalore, from September 2017 to September 2018. Male patients treated for disorders of the breast
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Khokhlov, Igor A., Dmitriy V. Belyaev, and Leonid A. Khazov. "Radiation methods for breast diseases diagnosis." Tambov Medical Journal 6, no. 1 (2024): 54–62. http://dx.doi.org/10.20310/2782-5019-2024-6-1-54-62.

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Abstract. Breast cancer is one of the most common and urgent healthcare issues. For primary diagnosis and clarification of the diagnosis of breast cancer specialists use most often such methods of breast examination as examination and palpation, computed tomography, magnetic resonance imaging, ultrasound, radionuclide examination of the mammary glands. Radiologists and mammalogists-oncologists face an important task of early detection of various forms of breast cancer, which enables to improve significantly the disease prognosis, as this is a priority. To solve the issue the world community is
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Dagistan, Emine, Betul Kizildag, Safiye Gurel, Yuksel Barut, and Esra Pasaoglu. "Radiologic and histopathologic review of rare benign and malignant breast diseases." Diagnostic and Interventional Radiology 23, no. 4 (2017): 286–92. http://dx.doi.org/10.5152/dir.2017.16085.

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Willsher, Peter. "The Breast: Comprehensive Management of Benign and Malignant Diseases (4th Edn)." ANZ Journal of Surgery 81, no. 1-2 (2011): 98. http://dx.doi.org/10.1111/j.1445-2197.2010.05617.x.

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Kim, Jong-Ki, Sung-Hwan Park, Hyun Mee Lee, et al. "In vivo 1H-MRS evaluation of malignant and benign breast diseases." Breast 12, no. 3 (2003): 179–82. http://dx.doi.org/10.1016/s0960-9776(03)00012-2.

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Köksoy, Cüneyt, Güzin Özelçi Kavas, Ethem Akçil, Pelin Aribal Kocatürk, Sevgi Kara, and Cihangir Özarslan. "Trace elements and superoxide dismutase in benign and malignant breast diseases." Breast Cancer Research and Treatment 45, no. 1 (1997): 01–06. http://dx.doi.org/10.1023/a:1005870918388.

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Huston, Tara L., and Rache M. Simmons. "Ablative therapies for the treatment of malignant diseases of the breast." American Journal of Surgery 189, no. 6 (2005): 694–701. http://dx.doi.org/10.1016/j.amjsurg.2005.03.011.

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Rudland, P. S., S. J. Leinster, J. Winstanley, B. Green, M. Atkinson, and H. D. Zakhour. "Immunocytochemical identification of cell types in benign and malignant breast diseases: variations in cell markers accompany the malignant state." Journal of Histochemistry & Cytochemistry 41, no. 4 (1993): 543–53. http://dx.doi.org/10.1177/41.4.8450194.

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We performed immunocytochemical staining of benign, in situ, and malignant breast disease to identify antigens related to the presence of the major parenchymal cell types of the normal breast. Markers for the epithelial cells, antiserum to epithelial membrane antigen, and three monoclonal antibodies (MAb) to milk-fat globule membranes stained most of the inner cells in benign breast lesions, carcinoma in situ, and invasive carcinomas, but the peripheral cells in benign lesions, as well as in carcinoma in situ, were unstained. MAb to epithelium-specific keratin 18 stained the majority of inner
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