Academic literature on the topic 'Metal Biguanides'

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Journal articles on the topic "Metal Biguanides"

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T., R. BERA, and KONAR J. "Thermal Behaviour of Metal Biguanides and their Iodine Adducts." Journal of Indian Chemical Society Vol. 74, Jul 1997 (1997): 528–31. https://doi.org/10.5281/zenodo.5901431.

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Department of Chemistry, Indian Institute of Technology, Kharagpur-721 302 <em>Manuscript received 17 July 1995, revised 3 June 1996, accepted 19 June 1996</em> 1 : 1 charge transfer adducts of Cu<sup>II</sup> and Ni<sup>II</sup> biguanides with I<sub>2</sub> have been prepared. Thermal characteristics of metal biguanides, substituted metal biguanides and their charge transfer adducts have been studied. The general features of the thermoanalytical traces are almost same except in case of iodine adducts. The evolution of iodine from the iodine adduct at appreciably lower temperature than the us
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Rani, Bina. "Coordination Chemistry of Cobalt Biguanide Complex: Ligand Interaction and Metal Complex Stability." International Journal for Research in Applied Science and Engineering Technology 13, no. 5 (2025): 7390–93. https://doi.org/10.22214/ijraset.2025.71822.

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Biguanides are versatile organic compounds known for their broad applications in medicinal chemistry, coordination chemistry, and catalysis. Biguanide, C₂N₅H₇ is a nitrogen donor bidentate ligand. Structurally, they contain two linked guanidine moieties, which enable strong chelation with metal ions, forming stable complexes. The ability of biguanides to interact with transition metals has led to the development of metal-biguanide complexes with remarkable biological and catalytic properties. These complexes exhibit diverse coordination modes influenced by steric and electronic factors, result
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Singh, Namrata, PratimaKatiyar PratimaKatiyar, Kalpana Kalpana, and Priyanka Sonker. "Biguanide scaffold: Chemistry, Stability and Pharmacophoric Features For Drug Discovery." Journal of Neonatal Surgery 14, no. 9S (2025): 126–35. https://doi.org/10.52783/jns.v14.2637.

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Around the world, biguanides like metformin are often used to treat type-2 diabetes. Biguanides were created as a result of the discovery of guanidine and similar substances in the French lilac plant (Galegaofficinalis L.). Using the common medication metformin, the produced compounds were tested for their anti-diabetic properties. Drugs' mechanisms of action are determined by their electrical and structural makeup. Pharmacophoric feature detection is aided by accurate structural depiction of medications. Although biguanide derivatives are a significant class of pharmaceuticals, little is know
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Grytsai, Oleksandr, Cyril Ronco, and Rachid Benhida. "Synthetic accesses to biguanide compounds." Beilstein Journal of Organic Chemistry 17 (May 5, 2021): 1001–40. http://dx.doi.org/10.3762/bjoc.17.82.

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Biguanide is a unique chemical function, which has attracted much attention a century ago and is showing resurgent interest in recent years after a long period of dormancy. This class of compounds has found broad applications such as reaction catalysts, organic strong bases, ligands for metal complexation, or versatile starting materials in organic synthesis for the preparation of nitrogen-containing heterocycles. Moreover, biguanides demonstrate a wide range of biological activities and some representatives are worldwide known such as metformin, the first-line treatment against type II diabet
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Prachi, Pahade, and Katolkar Parimal. "A SYSTEMATIC REVIEW ON METAL COMPLEXES OF SOME MEDICINAL COMPOUNDS." International Journal of Applied and Advanced Scientific Research (IJAASR) 5, no. 2 (2020): 9–21. https://doi.org/10.5281/zenodo.4013945.

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Metal ions plays an important role in biological processes and also in metal homeostasis. Metal imbalance in body may cause several diseases. To overcome such condition various derivatives of drugs are complexed with different metals like Cu, Zn, Mn, Ni, Co, Pt, Cd, Fe, Hg etc. Drugs like captopril, acyclovir, Biguanides, Theophylline, Chloriquine, triazole, Nicotinic acid and their derivatives hold medicinal properties such as&nbsp;&nbsp; ant neurodegenerative, anticancer, antioxidant, antimicrobial, anti-inflammatory, and antidiabetic activities. This article shows the synthesis of some nove
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SYAMAL, A. "ChemInform Abstract: Structure of Various Biguanides and Metal Complexes of Biguanides." ChemInform 26, no. 48 (2010): no. http://dx.doi.org/10.1002/chin.199548291.

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Rusanov, Daniil A., Jiaying Zou, and Maria V. Babak. "Biological Properties of Transition Metal Complexes with Metformin and Its Analogues." Pharmaceuticals 15, no. 4 (2022): 453. http://dx.doi.org/10.3390/ph15040453.

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Metformin is a widely prescribed medication for the treatment and management of type 2 diabetes. It belongs to a class of biguanides, which are characterized by a wide range of diverse biological properties, including anticancer, antimicrobial, antimalarial, cardioprotective and other activities. It is known that biguanides serve as excellent N-donor bidentate ligands and readily form complexes with virtually all transition metals. Recent evidence suggests that the mechanism of action of metformin and its analogues is linked to their metal-binding properties. These findings prompted us to summ
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François, AÏDOTE, KUEVI Urbain Amah, KPOTIN Assongba Gaston, and ATOHON Guy Sylvain. "DFT Study of Coordination of N-Monochlorosubstituation Derivatives of Biguanide." International Research Journal of Pure and Applied Chemistry 25, no. 6 (2024): 98–110. https://doi.org/10.9734/irjpac/2024/v25i6888.

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Biguanides [HN=C(NR1R2)-NH-C(NR3R4)=NH] constitute an important family of molecules used as drugs in the treatment of diabetes. It is known that some transition metal complexes with given organic compounds deeply increase both therapeutic actions of the metal and the organic compound. The chlorine atom, a preferred substitute in pharmacy, improves the effectiveness of drugs and reduces their side effects. The mesmeric +M effect of the chlorine atom would make it possible to enhance the nucleophilic character of any N-chlorosubstituted nitrogen. In this work a theoretical study of coordination
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Olar, Rodica, Mihaela Badea, and Mariana Carmen Chifiriuc. "Metal Complexes—A Promising Approach to Target Biofilm Associated Infections." Molecules 27, no. 3 (2022): 758. http://dx.doi.org/10.3390/molecules27030758.

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Microbial biofilms are represented by sessile microbial communities with modified gene expression and phenotype, adhered to a surface and embedded in a matrix of self-produced extracellular polymeric substances (EPS). Microbial biofilms can develop on both prosthetic devices and tissues, generating chronic and persistent infections that cannot be eradicated with classical organic-based antimicrobials, because of their increased tolerance to antimicrobials and the host immune system. Several complexes based mostly on 3D ions have shown promising potential for fighting biofilm-associated infecti
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Guha, Supriya, and Debabrata Banerjea. "Kinetics and mechanism of dissociation of copper(II) complexes of biguanide and someN 1-substituted biguanides in aqueous acetate buffer media." Transition Metal Chemistry 16, no. 4 (1991): 441–44. http://dx.doi.org/10.1007/bf01129460.

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Book chapters on the topic "Metal Biguanides"

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Rây, Priyadaranjan, and W. Conard Fernelius. "Metal Biguanide Complexes." In Inorganic Syntheses. John Wiley & Sons, Inc., 2007. http://dx.doi.org/10.1002/9780470132371.ch19.

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Ibrahim, Ahmad, Joseph-Émile Laquerre, Patricia Forcier, Vincent Deregnaucourt, Justine Decaens, and Olivier Vermeersch. "Antimicrobial Agents for Textiles: Types, Mechanisms and Analysis Standards." In Textiles for Functional Applications [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.98397.

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The large surface area, and ability to retain moisture of textile structures enable microorganisms’ growth, which causes a range of undesirable effects, not only on the textile itself, but also on the user. Moreover, textiles used in health care environments are required to possess antimicrobial property to minimize spread of pathogenic infection. Anti-microbial property can be imparted via chemical finishing with an antimicrobial agent. Currently the use of antimicrobial agents includes metal compounds (notably copper and silver particle), chitosan, halogenated phenols “triclosan”, quaternary
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