Academic literature on the topic 'N-acetyl derivatives'

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Journal articles on the topic "N-acetyl derivatives"

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Patel, H. S., and H. D. Desai. "Synthesis of Some New Azetidinone Derivatives Containing Aryl Sulfonyloxy Group." E-Journal of Chemistry 1, no. 4 (2004): 194–98. http://dx.doi.org/10.1155/2004/258752.

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Some novel azetidinone derivatives containing aryl sulfonyloxy group have been prepared. The 4-sulfonyloxy aniline derivative (2) has been prepared by reaction of 4-nitro phenol (sodium salt) with N-acetyl sulfanilyl chloride (ASC) followed by hydrolysis by ethanolic HCl. This compound (2) undergoes facile condensation reaction with aromatic aldehydes to yield different Schiff’s bases (3a-h). Cyclocondensation of compounds (3a-h) with chloro acetyl chloride yields different 2-azetidinone derivatives (4a-h).
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Kaválek, Jaromír, Josef Jirman, Vladimír Macháček, and Vojeslav Štěrba. "An anomalous effect of methyl group on acidity of acylthioureas." Collection of Czechoslovak Chemical Communications 52, no. 8 (1987): 1992–98. http://dx.doi.org/10.1135/cccc19871992.

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Dissociation constants and methanolysis rate constants have been measured of 1-acetyl- and 1-benzoylthioureas and their N-methyl derivatives. Replacement of hydrogen atom at N(1) (next to the acyl group) by methyl group increases the acidity of the benzoyl derivative by one order, that of the acetyl derivative by as much as two orders of magnitude. Replacement of both hydrogens at N(3) by methyl groups lowers the methanolysis rate constant by more than two orders, whereas the replacement of hydrogen atom at N(1) by methyl group increases the methanolysis rate by the factor of 30.
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Kaválek, Jaromír, Josef Jirman, and Vojeslav Štěrba. "Kinetics and mechanism of rearrangement and methanolysis of acylphenylthioureas." Collection of Czechoslovak Chemical Communications 50, no. 3 (1985): 766–78. http://dx.doi.org/10.1135/cccc19850766.

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S-Acyl-1-phenylthioureas and their 3-methyl derivatives are rearranged to 1-acyl derivatives of thiourea in methanolic solution. The rearrangement of the 1-acyl-1-phenyl derivative to the thermodynamically more stable 3-acyl derivative is subject to specific base catalysis. The rearrangement of acetyl group is about 2 orders of magnitude slower than that of benzoyl group. 1-Acetyl-l-phenylthiourea undergoes base-catalyzed methanolysis (giving phenylthiourea and methyl acetate) instead of the rearrangement. The methanolysis rates of l-acyl-3-phenylthioureas and their N-methyl derivatives have b
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Rodríguez, Ricaurte, Omar León, Felipe Quiroga, and Jonnathan Cifuentes. "N-{2-[(3-Oxo-1,3-dihydro-2-benzofuran-1-yl)acetyl]phenyl}acetamide." Molbank 2021, no. 3 (2021): M1244. http://dx.doi.org/10.3390/m1244.

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With the aim of obtaining different derivatives belonging to the isoindolo[2,1-a]quinoline family, we have synthesized a novel N-{2-[(3-oxo-1,3-dihydro-2-benzofuran-1-yl)acetyl]phenyl}acetamide derivative by a Claisen–Smichdt-type condensation reaction in 75% yield.
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Ibrahim, Hassan K., Sayed H. El-Tamany, Reda F. El-Shaarawy, and Ibrahim M. El-Deen. "Synthesis and investigation of mass spectra of some novel benzimidazole derivatives." Macedonian Journal of Chemistry and Chemical Engineering 27, no. 1 (2008): 65. http://dx.doi.org/10.20450/mjcce.2008.248.

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2-Substituted benzimidazoles (3) and (4a-c) were prepared via condensation of ethyl 2-thionyl-pyruvate (1) and hydrazidoyl derivatives (2a-c) with o-phenylene diamine in acetic acid. Acetylation of compound (4a) with acetic anhydride yielded the corresponding N-acetyl derivative (5). Treatment of compound 4b with hydrazine hydrate gave the corresponding hydrazino derivative (6). Reaction of 2-[(2-thionyl)acetyl)] benzimidazole (3) with hydrazine hydrate gave the pyrazolyl derivative (7) and hydrazino derivative (8). Alkylation of compound 3 with alkyl halide gave the corresponding 2,3-disubsti
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Hickman, RJS, BJ Christie, RW Guy, and TJ White. "Synthesis of Aromatic S-Sustituted Derivatives of N-Acetyl-L-cysteine." Australian Journal of Chemistry 38, no. 6 (1985): 899. http://dx.doi.org/10.1071/ch9850899.

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A new method for the preparation of aromatic, S-substituted derivatives of N-acetyl-L- cysteine is described. The method involves nucleophilic substitution of aromatic iodides by N-acetyl-L- cysteine in the presence of copper(I) iodide, and provides the first example of nucleophilic substitution of unactivated aromatic halides by N-acetyl-L- cysteine . The method has been used to prepare N-acetyl-S-(2-thienyl)-L- cysteine and N-acetyl-S-(3-thienyl)-L- cysteine from 2-iodothiophen and 3-iodothiophen respectively. In addition, the method has been successfully applied to iodobenzene and 1-iodonap
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Khan, Khalid A., Hassan M. Faidallah, and Abdullah M. Asiri. "Synthesis and Biological Evaluation of New N,N′-Bis(1-substituted-ethylidene)-ethane1,2-diamine and Their Acetyl and Trifluoroacetyl Derivatives as Cytotoxic and Antimicrobial Agents." Journal of Chemistry 2013 (2013): 1–9. http://dx.doi.org/10.1155/2013/478635.

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Several Schiff bases2have been prepared by the condensation of various methyl ketones1with 1,2-ethylenediamine. Subsequent acylation of these Schiff bases with trifluoroacetic anhydride in THF yields the corresponding trifluoroacetyl derivatives3. However,o-hydroxy- ando-methoxy-substituted derivatives yielded substituted-trifluoromethylchroman-4-ones. Additionally, Schiff bases when reacted with acetic anhydride afforded the C-acetylated derivatives4. The structures of the isolated compounds were fully determined by spectral methods. Preliminary biological screening of the prepared compounds
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Patel, H. S., H. D. Desai, and H. J. Mistry. "Synthesis and Antimicrobial Activity of Some New Piperazine Derivaties Containing Aryl Sulfonyloxy Group." E-Journal of Chemistry 1, no. 2 (2004): 93–98. http://dx.doi.org/10.1155/2004/732420.

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NovelN-substituted piperazine derivatives containing sulfonyloxy aniline moiety have been prepared. The various 4-sulfonyloxy aniline (SA) derivatives (2a-h) have been prepared by the condensation reaction ofN-Acetyl Sulfanilyl chloride (ASC) and sodium phenates followed by hydrolysis. The SA derivatives are then reacted with chloro acetyl chloride to give corresponding (N-Chloroacetyl) derivatives (3a-h). These derivatives are then reacted withN-phenyl piperazine to yield the corresponding piperazine derivatives (4a-h).
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Feng, Jianhao, and Chang-Chun Ling. "An efficient conversion of N-acetyl-d-glucosamine to N-acetyl-d-galactosamine and derivatives." Carbohydrate Research 345, no. 17 (2010): 2450–57. http://dx.doi.org/10.1016/j.carres.2010.09.008.

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Zhang, Jingjing, Wenqiang Tan, Qing Li, Fang Dong, and Zhanyong Guo. "Synthesis and Characterization of N,N,N-trimethyl-O-(ureidopyridinium)acetyl Chitosan Derivatives with Antioxidant and Antifungal Activities." Marine Drugs 18, no. 3 (2020): 163. http://dx.doi.org/10.3390/md18030163.

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Chitosan is an active biopolymer, and the combination of it with other active groups can be a valuable method to improve the potential application of the resultant derivatives in food, cosmetics, packaging materials, and other industries. In this paper, a series of N,N,N-trimethyl-O-(ureidopyridinium)acetyl chitosan derivatives were synthesized. The combination of chitosan with ureidopyridinium group and quaternary ammonium group made it achieve developed water solubility and biological properties. The structures of chitosan and chitosan derivatives were confirmed by FTIR, 1H NMR spectra, and
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Dissertations / Theses on the topic "N-acetyl derivatives"

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Gregar, Travis Quinton. "Synthesis and structural characterization of amide-linked derivatives of N-acetyl neuraminic acid." Diss., The University of Arizona, 2001. http://hdl.handle.net/10150/279827.

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Amide linked carbohydrates represent a tremendously different type of compound. Sugars have traditionally been linked together as either N or O linked via the anomeric carbon to make larger compounds, i.e. Sialyl Lewis X. This linkage leads to great instability under acidic and biological conditions. N-Acetyl neuraminic acid is a naturally occurring delta peptide. Colominic acid is the naturally occurring O linked polymer of N-acetyl neuraminic acid. This polymer has been found to possess a helical structure starting at the hexamer length. Changing from an O linkage to an amide linkage provid
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Drieman, Johannes Cornelis. "Drug targeting to the kidney N-acetyl-L-[gamma]-glutamyl derivatives as kidney-selective prodrugs /." Maastricht : Maastricht : Datawyse ; University Library, Maastricht University [Host], 1989. http://arno.unimaas.nl/show.cgi?fid=6187.

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Cox, Glen Adam. "Towards the Synthesis of N-Acetyl-2-amino-2-deoxy-D-mannopyranose uronic acid (D-ManNAcA) and Derivatives." Youngstown State University / OhioLINK, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=ysu1217344144.

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Buabeng, Emmnauel Ramsey. "Towards the Synthesis of Novel Glycomimetics of N-Acetyl-2-amino-2-deoxy-D-mannopyranose uronic acid (D-ManNAcA) and Derivatives." Youngstown State University / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=ysu1471478050.

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Chaudhry, Humayun Iqbal. "An evaluation of the performance and mechanistic action of the costabiliser N-phenyl-3-acetyl pyrrolidine-2,4-dione and its derivatives in poly(vinyl chloride)." Thesis, Manchester Metropolitan University, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.311051.

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YU, CHUNG FEN, and 鍾芬裕. "Synthesis of Novel N-Acetyl-N-hydroxy amino Thymidine Derivatives." Thesis, 2001. http://ndltd.ncl.edu.tw/handle/61563394564179423330.

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碩士<br>朝陽科技大學<br>應用化學系碩士班<br>89<br>Abstract In this thesis we discuss on the synthesis of compound 42 ,which contains bicyclic deoxynucleose. Two other new compounds, 20 and 21,were obtained during the synthesis process. By applying Mitsunobu method , we have synthesized compound 43. The acetyl group of compound 43 was then hydrolyzed and became compound 42. By cooperating with pharmacologists , we are now evaluating the biological activities of these compounds. We hope that some useful compounds could be su
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Shieh, Chung-Yee, and 謝忠益. "The study and synthesis of N-acetyl-leucyl-leucyl-norleucinal derivatives." Thesis, 2002. http://ndltd.ncl.edu.tw/handle/y5u4jc.

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碩士<br>國立成功大學<br>臨床藥學研究所<br>90<br>英文摘要 P-glycoprotein (Pgp), the multidrug resistance gene (mdr1) product, reduces the intracellular accumulation of a variety of drugs by pumping drugs out of membranes. Studies have demonstrated that hydrophobic tripeptides N-acetyl- leucyl- leucyl-norleucinal (ALLN), N-acetyl- leucyl-leucyl-methiminal (ALLM) and N-acetyl-leucyl-leucyl-arginal (leupeptin) are Pgp substrates/inhibitors. We would like to synthesize a series of tripeptides (N-acetyl-leu-leu-X ) and to study the interaction between the tripeptides and Pgp. We employ liquid-phase peptide synthesis
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Liu, Fu-Chien, and 劉福千. "Efficient 1H NMR method for quality analysis of the enzyme hydrolyzed products of chitin and using 1H-NMR to study the dynamic behavior of N-acetyl-D-glucosamine derivatives." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/74267706736676243129.

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碩士<br>國立成功大學<br>化學系碩博士班<br>95<br>Chitinase (EC 3.2.1.14) hydrolyzes ��-1,4-glycosidic linkages of chitin .The most widely used method for the analysis of the chitinase-catalyzed hydrolysis products of ��- and ��-chitin is HPLC. However, this method associated with disadvantages such as the enzyme must be deactivated and filtered by dialytic membrane before going to separate by HPLC analysis and also needed the calibration curves to determine quantitatively the contents of chitin hydrolysis products. In the present study, a 1H NMR method was developed to analyze the chitinase-catalyzed chitin h
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Books on the topic "N-acetyl derivatives"

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Nguyen, Thach-Mien Duong. Decomposition kinetics and azide trapping of ester derivative of A C, N-acetyl-N-acetoxy-2-amino- -carboline. 2002.

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Nguyen, Thach-Mien Duong. Decomposition kinetics and azide trapping of ester derivative of A C, N-acetyl-N-acetoxy-2-amino- -carboline. 2002.

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Book chapters on the topic "N-acetyl derivatives"

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David, Serge. "Sialic acids and sialylated oligosaccharides." In The Molecular and Supramolecular Chemistry of Carbohydrates: Chemical Introduction to the Glycosciences. Oxford University PressOxford, 1997. http://dx.doi.org/10.1093/oso/9780198500476.003.0012.

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Abstract Natural sialic acids (Schauer 1982; 1991) are derivatives of 5-amino-3,5-dideoxy-D-glycero-D-galacto-nonulosonic acid 12.1. This awkward name has been replaced by ‘neuraminic acid’. The most common derivative is N-acetyl-neuraminic acid 12.2 whose configuration is easy to memorize because, in the Fischer representation, 12.3, it is presented as an aldolic condensation product of N-acetylmannosamine (2-acetamido-2-deoxy-o-mannose) and pyruvic acid. When the expression ‘sialic acid’ is used without any other precision, it is in reference to derivative 12.2. It exists in the free state o
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Mohammed, Mohsin, and Nadia Haj. "Preparation and Bioactivity Applications of Novel Chitosan Derivatives." In Chitin-Chitosan - Isolation, Properties, and Applications [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.105796.

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Chitosan (CS) is a substance abundant in nature. It is a biopolymer consisting of repetitive components of glucose and N-acetyl-glucose amine connected by (1,4)-glycosidic bonds. It has so many applications that are biodegradable, non-toxic, and biocompatible. The CS was loaded with 5-fluorouracil (5FU) via amide-mediated binding, and the resulting CSFUAC product was evaluated as a potential 5FU delivery agent. A new CS-Schiff base derivative was created using CS extracted from local fish scales by combining CS with another aromatic aldehyde. The antimicrobial effectiveness of the new product
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Anores, Gustavo, Nobuo Hana, Isteven Blevery, Hugh L. Eaton, Mary Ellen K. Salyan, and Sen-itiroh Hakomori. "[16] Synthesis and Characterization of Ganglioside GM3 Derivatives: Lyso-GM3, De-N-acetyl-GM3, and Other Compounds." In Complex Carbohydrates Part F. Elsevier, 1989. http://dx.doi.org/10.1016/0076-6879(89)79124-2.

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Merhan, Oguz. "Biochemistry and Antioxidant Effects of Melatonin." In Melatonin - Recent Updates [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.106260.

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Melatonin (N-acetyl-5-methoxy-tryptamine) is a hormone taking place in many biological and physiological processes, such as reproduction, sleep, antioxidant effect, and circadian rhythm (biological clock), and is a multifunctional indolamine compound synthesized mainly from the metabolism of tryptophan via serotonin in the pineal gland. Melatonin, which is a hormone synthesized from the essential amino acid tryptophan, is substantially secreted from the pineal gland between the cerebral hemispheres found in the mammalian brain. In addition to this, it is also produced in the cells and tissues,
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Conference papers on the topic "N-acetyl derivatives"

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Muškinja, Jovana, Sanja Matić, Snežana Stanić, and Zoran Ratković. "Synthesis of N-acetyl and N-formyl pyrazoline derivatives from vanillin and their antigenotoxic activity." In 5th International Electronic Conference on Medicinal Chemistry. MDPI, 2019. http://dx.doi.org/10.3390/ecmc2019-06358.

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Dinh Thanh, Nguyen, Dang Nhu Tai, Do Son Hai, Nguyen Thu Huyen та Pham Hong Lan. "Derivatives of N-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-N'- (benzothiazole-2'-yl)thioureas". У The 13th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2009. http://dx.doi.org/10.3390/ecsoc-13-00154.

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Levene, C., T. J. Dines, S. Ostavour pour та ін. "An Experimental And Theoretical Raman and ROA Study Of Di-amino Acid Peptides (DAAPs): α- and β-N-acetyl-L-Asp-L-Glu And Their Derivatives: N-acetyl-L-Asp, N-acetyl-L-Glu and L-Asp-L-Glu". У XXII INTERNATIONAL CONFERENCE ON RAMAN SPECTROSCOPY. AIP, 2010. http://dx.doi.org/10.1063/1.3482842.

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Radojević, Ivana, Edina Avdović, Dušan Dimić, Marko Antonijević, Marijana Vasić та Katarina Ćirković. "ANTIMICROBIAL ACTIVITY OF HYBRIDS OF COUMARIN’S DERIVATIVES WITH NEUROTRANSMITTERS 20242ND INTERNATIONAL SYMPOSIUM ON BIOTECHNOLOGY (2024)ЗБОРНИЦИ". У 2nd International Symposium on Biotechnology. Faculty of Agronomy in Čačak, University of Kragujevac, 2024. http://dx.doi.org/10.46793/sbt29.70ir.

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n this study, the antimicrobial activity of five hybrids of 3-acetyl- 4-hydroxy coumarin with neurotransmitters was determined: dopamine (1), tyramine (2), octopamine (3), norepinephrine (4) and methoxy-tyramine (5). Antimicrobial activity was assessed using the microdilution method incorporating resazurin, with determination of MIC/MMC concentrations. Testing involved twelve microorganisms, five of which were sourced from mine wastewater. The best activities were shown by substances (1) and (4) on Bacillus pumilus and Pantoea agglomerans, where the MIC was 31.8 μg/mL. Pantoea agglomerans show
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Cin, Gunseli Turgut, Seda Demirel Topel, Neslihan Nohut Maslakci, Esin Eren, and Aysegul Uygun Oksuz. "Plasma modified chitosan/N-acetyl-2-pyrazoline derivative nanofibers." In 2015 IEEE International Conference on Plasma Sciences (ICOPS). IEEE, 2015. http://dx.doi.org/10.1109/plasma.2015.7179648.

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Avdović, Edina, Sandra Jovičić Milić, Dušica Simijonović, Danijela Stojković, Dejan Milenković, and Zoran Marković. "SYNTHESIS, SPECTROSCOPIC CHARACTERIZATION AND BSA INTERACTIONS OF 3-(1-((4-HYDROXY PENTYLAMINO)ETHYLIDENE)CHROMAN-2,4-DIONE." In 17th International Conference on Fundamental and Applied Aspects of Physical Chemistry. Society of Physical Chemists of Serbia, 2024. https://doi.org/10.46793/phys.chem24i.053a.

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In this study, we synthesized a novel coumarin derivative, specifically 3-(1-((4-hydroxy pentylamino)ethylidene)cromane-2,4-dione by the reaction of 3-acetyl-4-hydroxycoumarin and 5- aminopentanol in methanol. The compound was obtained after 2 hours of reflux. The synthesized coumarin derivative was obtained in very good yield (80%) and characterized using elemental microanalysis, Uv-Vis, IR and NMR spectroscopy. Furthermore, the interaction of investigated compound with bovine serum albumin (BSA) was studied using fluorescence spectroscopy and the Stern-Volmer constant (Ksv), quenching rate c
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Petrovskaya, M. A. "EXPERIMENTAL MORPHOLOGICAL ANALYSIS OF THE HEALING OF SKIN BURNS IN RATS UNDER THE INFLUENCE OF OINTMENT WITH A NEW DERIVATIVE OF N-ACETYL-6-AMINOHEXANOIC ACID." In НАУЧНЫЕ ОСНОВЫ ПРОИЗВОДСТВА И ОБЕСПЕЧЕНИЯ КАЧЕСТВА БИОЛОГИЧЕСКИХ ПРЕПАРАТОВ. Б. и., 2022. http://dx.doi.org/10.47804/9785899040313_2022_218.

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