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Relevant bibliographies by topics / N-acyl derivatives

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Academic literature on the topic 'N-acyl derivatives'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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Journal articles on the topic "N-acyl derivatives"

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Kaválek, Jaromír, Josef Jirman, and Vojeslav Štěrba. "Kinetics and mechanism of rearrangement and methanolysis of acylphenylthioureas." Collection of Czechoslovak Chemical Communications 50, no. 3 (1985): 766–78. http://dx.doi.org/10.1135/cccc19850766.

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S-Acyl-1-phenylthioureas and their 3-methyl derivatives are rearranged to 1-acyl derivatives of thiourea in methanolic solution. The rearrangement of the 1-acyl-1-phenyl derivative to the thermodynamically more stable 3-acyl derivative is subject to specific base catalysis. The rearrangement of acetyl group is about 2 orders of magnitude slower than that of benzoyl group. 1-Acetyl-l-phenylthiourea undergoes base-catalyzed methanolysis (giving phenylthiourea and methyl acetate) instead of the rearrangement. The methanolysis rates of l-acyl-3-phenylthioureas and their N-methyl derivatives have b

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Romanov, V. E., E. E. Shul’ts, M. M. Shakirov, and G. A. Tolstikov. "New acyl derivatives of N-deacetyllappaconitine." Chemistry of Natural Compounds 44, no. 3 (2008): 346–51. http://dx.doi.org/10.1007/s10600-008-9058-3.

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Kutschy, Peter, Milan Dzurilla, Vlastimír Ficeri, and Dušan Koščík. "New Synthesis of N-Acylurea Derivatives." Collection of Czechoslovak Chemical Communications 58, no. 3 (1993): 575–87. http://dx.doi.org/10.1135/cccc19930575.

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S-Allyl N-acylmonothiocarbamates react in boiling benzene with primary and secondary amines in the presence of catalytic amounts of triethylamine. In this reaction, the S-allyl group is replaced with the amino group under formation of N-acylurea derivatives in 45 - 90% yields. The wide applicability of the reaction is demonstrated by the synthesis of eighty four N-acyl-N'-substituted and N-acyl-N',N'-disubstituted ureas with various aliphatic, aromatic and heterocyclo substituents.

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Mangroo, Dev, and Gerhard E. Gerber. "Synthesis of acyl-CoA thioesters." Biochemistry and Cell Biology 68, no. 1 (1990): 308–12. http://dx.doi.org/10.1139/o90-042.

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An improved synthesis of fatty acyl coenzyme A has been developed that permits the synthesis of highly radioactive fatty acyl coenzyme A derivatives and thus can be used for the synthesis of high specific activity photoaffinity labels. Conditions were developed to solubilize the coenzyme A in anhydrous solvent for the acylation. The complete activation of fatty acid to the imidazolide is described and the acylation of the coenzyme A under anhydrous conditions was shown to result in the conversion of the fatty acid to the fatty acyl coenzyme A derivative. The synthetic product was shown by its

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Hirano, Shigehiro, Ken-ichiro Hayashi, and Keiji Hirochi. "Some N -acyl derivatives of O -carboxymethylchitosan." Carbohydrate Research 225, no. 1 (1992): 175–78. http://dx.doi.org/10.1016/0008-6215(92)80052-3.

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Isobaev, M. D., and E. Kh Pulatov. "N-Acyl andN-sulfonyl derivatives of thiazolidines." Russian Chemical Bulletin 45, no. 12 (1996): 2820–22. http://dx.doi.org/10.1007/bf01430651.

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Kochetkov, K. A., Zh S. Urmambetova, V. M. Belikov, and Z. B. Bakasova. "Higher N-acyl-L-amino acid derivatives." Bulletin of the Academy of Sciences of the USSR Division of Chemical Science 39, no. 11 (1990): 2311–16. http://dx.doi.org/10.1007/bf00958844.

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Zosimo-Landolfo, Guido, Jean M. J. Tronchet, and Ford Habashi. "N- and O-acyl derivatives of Deoxy-N-hydroxyaminosugars." Journal f�r Praktische Chemie/Chemiker-Zeitung 336, no. 3 (1994): 273–76. http://dx.doi.org/10.1002/prac.19943360318.

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9

Dang, Chi-Hien, Cong-Hao Nguyen, Thanh-Danh Nguyen, and Chan Im. "Synthesis and characterization of N-acyl-tetra-O-acyl glucosamine derivatives." RSC Advances 4, no. 12 (2014): 6239. http://dx.doi.org/10.1039/c3ra46007j.

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Sawada, S., T. Yokokura, and T. Miyasaka. "Synthesis and Antitumor Activity of A-Ring or E-Lactone Modified Water Soluble Prodrugs of 20(S)-Camptothecin, Including Development of Irinotecan Hydrochloride Trihydrate (CPT-11)." Current Pharmaceutical Design 1, no. 1 (1995): 113–32. http://dx.doi.org/10.2174/1381612801666220524193614.

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Camptothecin was converted into derivatives which have substituents on the A- and B rings . One potent and less toxic derivative , 7-ethyl-10-hydroxycamp-tothecin (SN-38), was selected and then converted into glycosides, sulfates, phosphates and carbamates at the 10-hydroxyl group. Among these water-soluble, E-lactone-intact derivatives , the hydrochloride trihydrate of 7-ethyl-10 - [(4-piperidinopiperidine )carbony loxy]camptothecin(irinotecan hydrochloride trihydrate , CPT-11) had a broad spectrum of antitumor activity and seems to be a promising anticancer agent with a new mode of action.

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Dissertations / Theses on the topic "N-acyl derivatives"

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Al-Faiyz, Yasair S. S. "The chemistry of O-acyl derivatives of N-acyl hydroxamic acid." Thesis, University of Warwick, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.252534.

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Patel, Divya. "The synthesis and rearrangement of N-alkyl-O-acyl hydroxamic acid derivatives." Thesis, University of Warwick, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.400109.

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Kaskah, Saad Elias [Verfasser], Christian B. [Akademischer Betreuer] Fischer, Jörg [Akademischer Betreuer] Gollnick, Christian B. [Gutachter] Fischer, and Jörg [Gutachter] Gollnick. "Surface protection of steel CR4 by using N-acyl sarcosine derivatives in salt water / Saad Elias Kaskah ; Gutachter: Christian B. Fischer, Jörg Gollnick ; Christian B. Fischer, Jörg Gollnick." Koblenz, 2018. http://d-nb.info/1168627869/34.

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Books on the topic "N-acyl derivatives"

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Al-Faiyz, Yasair S. S. The chemistry of O-acyl derivatives of N-acyl hydroxamic acid. typescript, 2002.

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Book chapters on the topic "N-acyl derivatives"

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Okusecyama, Tadashi, and Howard Maskill. "Nucleophilic Substitution Reactions of Carboxylic Acid Derivatives." In Organic Chemistry. Oxford University Press, 2013. http://dx.doi.org/10.1093/hesc/9780199693276.003.0009.

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This chapter concentrates on the interconversions of carboxylic acid derivatives, which generally take place by nucleophilic substitution via addition-elimination mechanisms. It first describes carboxylic acids which contain a carboxy functional group (a carbonyl with a hydroxy group attached) bonded to an alkyl residue. Carboxylic acid derivatives, on the other hand, are obtained by replacing the hydroxy with another group bonded through O, N, S, or halogen. This class of compounds includes esters (Y = OR'), anhydrides (Y = OCOR'), amides (Y = NR' 2), and acyl halides (Y = halogen). The chapt

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D. Adesina, Adebimpe. "The Chemistry of Benzo and Carbocyclic Derivatives of Pyridine." In Exploring Chemistry with Pyridine Derivatives [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.108127.

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The chemistry of pyridine and its derivatives is of considerable importance in the synthesis of intermediates leading to biologically active compounds and novel materials. Generally, derivatives of pyridine are stable and relatively unreactive but can be attacked by electrophiles at ring nitrogen and certain carbon atoms. Pyridines undergo radical substitution reactions preferentially at the 2-position. Simple pyridines and their benzo derivatives are weak bases that form salts with strong acids. Various Lewis acids form complexes with pyridine and its benzo derivatives. The quaternization of

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Kirschke, Heidrun, Alan J. Barrett, and Neil D. Rawlings. "Reaction with inhibitors." In Lysosmal Cysteine Proteases. Oxford University PressOxford, 1998. http://dx.doi.org/10.1093/oso/9780198502494.003.0011.

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Abstract Cysteine proteinases contain a highly reactive cysteine residue in their active centre. They react readily with many thiol-blocking reagents, such as Hg2+ derivates, disulfides, heavy metal ions, iodoacetate and N-ethylmaleimide. To achieve a more selective reaction with the enzymes rather than with SH-containing compounds generally, several peptidyl derivatives can be used. Compounds of this type can show selectivity amongst the cysteine proteinases. As will be shown in this section, nearly all of the synthesized cysteine proteinase inhibitors react (in some cases very weakly) with s

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OMELYANCHIK, Luydmyla, Oleksandr BRAZHKO, Viktoriia GENCHEVA, Iryna LABENSKA, and Yuliіa PETRUSHA. "SYNTHESIS AND PHYSICOCHEMICAL PROPERTIES OF N-ACYL DERIVATIVES OF S-(2-METHYLQUINOLINE-4-YL)-L-CYSTEINE." In SCIENTIFIC RESEARCH OF THE XXI CENTURY.VOLUME 1. GS publishing service, 2021. http://dx.doi.org/10.51587/9781-7364-13302-2021-001-7-18.

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Taber, Douglass. "New Methods for the Stereoselective Construction of N-Containing Rings." In Organic Synthesis. Oxford University Press, 2011. http://dx.doi.org/10.1093/oso/9780199764549.003.0053.

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Several methods have been reported for the stereocontrolled preparation of pyrrolidine and piperidine derivatives. Alison J. Frontier of the University of Rochester has observed (Organic Lett. 2007, 9, 4939) that hydrogenation of acyl pyrroles such as 1 gave good control not just around the ring, but also on the sidechain. Chi-Ming Che of the University of Hong Kong has devised ( J. Am. Chem. Soc. 2007, 129, 5828) a catalyst that converted amides such as 3 into the cyclized product 4, also with high diastereocontrol. Jean Ollivier of the Université de Paris-Sud, following the Sato procedure, h

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Conference papers on the topic "N-acyl derivatives"

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Branković, Jovica, Zorica D. Petrović, and Vladimir P. Petrović. "Phenolic N-acyl hydrazone derivatives: In silico assessment of potential antibacterial activity against selected G+ and G- strains." In 2nd International Conference on Chemo and Bioinformatics. Institute for Information Technologies, University of Kragujevac, 2023. http://dx.doi.org/10.46793/iccbi23.491b.

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In this work, a series of phenolic N-acyl hydrazones was investigated in silico against six selected E. coli and S. aureus bacterial proteins. Generally, the obtained molecular docking results revealed significantly higher binding affinities of analogs a–n towards selected enzymes in comparison to standard compounds. In the case of E. coli proteins 1hnj, 1c14, and 6ntw, the lowest binding energies were calculated for derivatives l (-8.5 kcal/mol), d (-9.0 kcal/mol), and k (-8.2 kcal/mol), respectively. On the other hand, the highest binding affinity towards the S. aureus 3u2d, 1mwu, and 1jij e

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Branković, Jovica, Zorica D. Petrović, and Vladimir P. Petrović. "In silico antibiofilm potency of phenolic N-acyl hydrazones against selected bacterial strains." In 2nd International Conference on Chemo and Bioinformatics. Institute for Information Technologies, University of Kragujevac, 2023. http://dx.doi.org/10.46793/iccbi23.495b.

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In the present work, fourteen phenolic hydrazone derivatives were evaluated for their in silico inhibitory activity against selected P. aeruginosa and S. maltophilia proteins involved in drug resistance and biofilm formation. Molecular docking analysis revealed the highest binding affinity of analogs n (-8.4 kcal/mol) and h (-7.3 kcal/mol) towards P. aeruginosa 7m1m and 7m1l proteins, respectively. In the case of S. maltophilia, analog k (-8.4 kcal/mol) expressed the highest binding affinity to 6qw7, whereas for 6uaf, the lowest binding energy was calculated for derivative d (-8.1 kcal/mol). T

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Vítovcová, Miloslava, Jan Hlaváček, Jan Pícha, Václav Vaněk, Jiří Jiráček, and Václav Kašička. "Capillary electrophoresis applied to analysis and characterization of mono-N-acyl-2,6-diaminopimelic acid derivatives." In XIIth Conference Biologically Active Peptides. Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 2011. http://dx.doi.org/10.1135/css201113159.

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García-Domenech, Ramón, Maria Angeles Martinez Rodriguez, Raimundo Segui Lopez-Peñalver, Gemma Alcacer Tomas, Jorge Galvez, and Maria Galvez-Llompart. "Application of molecular topology to the prediction and optimization of mosquito repellent activity of N-acyl-piperidine derivatives ." In MOL2NET 2017, International Conference on Multidisciplinary Sciences, 3rd edition. MDPI, 2017. http://dx.doi.org/10.3390/mol2net-03-04863.

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