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1

Popovych, Andriy, Dariya Popovych, Sofiya Ruzhylo, et al. "Comparative study of the effects of fresh and canned Naftussya bioactive water on neuro-endocrine-immune complex and metabolism in chronic pyelonephritis patients." Journal of Education, Health and Sport 17, no. 1 (2023): 11–20. http://dx.doi.org/10.12775/jehs.2023.17.01.001.

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Background. There are several patented methods of preservation of medicinal waters of the Naftussya type. The authors of the patents as evidence of the correctness of the methods cite the facts of preservation of the ability of canned water to enhance motility rat’s v. portae in vitro and/or increase diuresis. However, such tests are not attributive. The most characteristic manifestation of the biological activity of Naftussya water is the stimulation of phagocytosis through the mediation of the nervous and endocrine systems. Another "Method of preservation of hydrogen sulfide mineral waters"
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2

Popovych, Andriy, Sofiya Ruzhylo, Nataliya Zakalyak, Dariya Popovych, and Xawery Żukow. "Comparative study of the effects on the microbiota and leukocyturia of fresh and canned Naftussya water." Quality in Sport 8, no. 4 (2022): 67–72. http://dx.doi.org/10.12775/qs.2022.08.04.007.

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Background. Balneotherapy has its rightful place in the arsenal of means of treatment of chronic. The universally recognized gold standard of balneofactors is Naftussya bioactive water. The issue of the loss of its healing properties by Naftussya water after extraction from the subsoil, the possibility of its preservation and transportation remain debatable and relevant. The purpose of this study is to compare the impact of fresh and canned water on the microbiota of feces and urine in patients with chronic pyelonephritis. Materials and Methods. The object of clinical-physiological observation
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3

Fihura, Oksana, Sofiya Ruzhylo, and Nataliya Zakalyak. "Phytoadaptogen reverses the adverse effects of Naftussya bioactive water on dynamic muscle performance in healthy rats." Quality in Sport 8, no. 2 (2022): 45–55. http://dx.doi.org/10.12775/qs.2021.08.02.004.

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Background.. Muscular performance is considered one of the attributes of health and non-specific resistance. Phytoadaptogens occupy an important place in the arsenal of means of increasing non-specific resistance and stress resistance. Many years of research of the Truskavetsian Scientific School of Balneology have demonstrated the adaptogenic properties of the main therapeutic factor of the resort, Naftussya bioactive water, as well as ozokerite and mineral baths. However, in contrast to the beneficial effect of the latter on stress resistance and the neuro-endocrine-immune complex, the effec
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4

Fihura, Oksana, Sofiya Ruzhylo, and Nataliya Zakalyak. "Phytoadaptogen reverses the adverse effects of Naftussya bioactive water on dynamic muscle performance in healthy rats." Quality in Sport 8, no. 2 (2022): 45–55. http://dx.doi.org/10.12775/qs.2022.08.02.004.

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Background.. Muscular performance is considered one of the attributes of health and non-specific resistance. Phytoadaptogens occupy an important place in the arsenal of means of increasing non-specific resistance and stress resistance. Many years of research of the Truskavetsian Scientific School of Balneology have demonstrated the adaptogenic properties of the main therapeutic factor of the resort, Naftussya bioactive water, as well as ozokerite and mineral baths. However, in contrast to the beneficial effect of the latter on stress resistance and the neuro-endocrine-immune complex, the effec
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5

Popovych, Igor L. "Similarity of adaptogenic effects of bioactive naftussya water and phytocomposition “Balm Truskavets’”." Journal of Education, Health and Sport 12, no. 12 (2023): 344–56. http://dx.doi.org/10.12775/jehs.2022.12.12.052.

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Background. From previous studies, it is known about the adaptogenic properties of Naftussya bioactive water and the Ukrainian phytocomposition "Balm Truskavets’". Both adaptogens have a common component of the composition - polyphenols, which suggests the existence of similar effects on the parameters of the body responsible for adaptation. The purpose of this study is to test the hypothesis. Material and methods. The object of clinical-physiological observation were 30 practically healthy individuals of both sexes with dysfunction of the neuro-endocrine-immune complex as a manifestation of m
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6

Popovych, Igor L., Myroslav D. Gumega, Igor E. Verba, et al. "Comparative investigation effects on nervous and immune systems of bioactive water Naftussya Spa Truskavets' and stable water solution of Boryslav's Ozokerite." Journal of Education, Health and Sport 6, no. 4 (2016): 364–74. https://doi.org/10.5281/zenodo.8023107.

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<strong>Popovych I</strong><strong>gor </strong><strong>L</strong><strong>, Gumega Myroslav D,</strong> <strong>Verba Igor E, Popovych Andriǐ I, Korolyshyn Tetyana A, Tkachuk Svitlana P, Ostapenko&nbsp;Volodymyr M, Zukow Walery. Comparative investigation effects on nervous and immune systems of bioactive water Naftussya Spa Truskavets&rsquo; and stable water solution of Boryslav&rsquo;s O</strong><strong>zokerite.</strong> <strong>Journal of Education, Health and Sport. 2016;6(4):</strong><strong>364</strong><strong>-3</strong><strong>74</strong><strong>. eISSN 2391-8306. DOI </strong><strong>
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7

POPOVYCH, Andriy, Dariya POPOVYCH, Sofiya RUZHYLO, et al. "Comparative study of the effects of fresh and canned Naftussya bioactive water on neuro-endocrine-immune complex and metabolism in chronic pyelonephritis patients." Journal of Education, Health and Sport 17, no. 1 (2023): 11–20. https://doi.org/10.12775/JEHS.2023.17.01.001.

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<strong>POPOVYCH, Andriy, POPOVYCH, Dariya, RUZHYLO, Sofiya, ZAKALYAK, Nataliya, ZUKOW, Xawery, SHYPYTIAK,&nbsp;Yevstakhii &amp; FIL, Vitalij. Comparative study of the effects of fresh and canned Naftussya bioactive water on neuro-endocrine-immune complex and metabolism in chronic pyelonephritis patients.</strong>&nbsp;<strong>Journal of Education, Health and Sport. 2023;1</strong><strong>7</strong><strong>(1):</strong><strong>11</strong><strong>-</strong><strong>20</strong><strong>. eISSN 2391-8306. DOI </strong><strong>http://dx.doi.org/10.12775/JEHS.2023.1</strong><strong>7</strong><strong>
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8

Hrytsak, Myroslava, Dariya Popovych, Nataliya Badiuk, Ivanna Hrytsan, and Xawery Żukow. "Comparative study of the effect on the neuroendocrine-immune complex and metabolism of drinking monotherapy with Naftussya water and therapy supplemented with “Myroslava” and “Khrystyna” mineral waters." Journal of Education, Health and Sport 12, no. 1 (2022): 355–67. http://dx.doi.org/10.12775/jehs.2022.12.01.031.

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Background. Earlier in an experiment on rats, we showed that the newly created sulfate-chloride sodium-magnesium drinking mineral waters of Truskavets’ spa have neuroendocrine and metabolic effects significantly different from daily water. Adhering to the principle "From experiment to clinic", we continued research in this direction with the participation of patients of the resort. Materials and Methods. The object of clinical-physiological observation were 34 men aged 23-70 years, who underwent rehabilitation treatment of chronic cholecystitis and pyelonephritis in remission in the Truskavets
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9

Hrytsak, Myroslava, Dariya Popovych, Nataliya Badiuk, Ivanna Hrytsan, and Xawery Zukow. "Comparative study of the effects on the EEG of drinking monotherapy with Naftussya water and therapy supplemented with “Myroslava” and “Khrystyna” mineral waters." Journal of Education, Health and Sport 12, no. 2 (2022): 141–50. http://dx.doi.org/10.12775/jehs.2022.12.02.016.

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Background. Earlier we showed that the newly created sulfate-chloride sodium-magnesium drinking mineral waters of Truskavets’ spa have favorable effects on metabolism and neuroendocrine-immune complex of patients with their dysfunction. This report analyzes the effect of balneotherapy on the parameters of the electroencephalogram of the same contingent of patients. Materials and Methods. The object of clinical-physiological observation were 34 men aged 23-70 years, who underwent rehabilitation treatment of chronic cholecystitis and pyelonephritis in remission in the Truskavets’ spa. The examin
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10

POPOVYCH, Igor L. "Similarity of adaptogenic effects of bioactive naftussya water and phytocomposition "Balm Truskavets'"." Journal of Education, Health and Sport 12, no. 12 (2023): 344–56. https://doi.org/10.12775/JEHS.2022.12.12.052.

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<strong>POPOVYCH, Igor L. Similarity of adaptogenic effects of bioactive naftussya water and phytocomposition &ldquo;Balm Truskavets&rsquo;&rdquo;</strong><strong>. </strong><strong>Journal of Education, Health and Sport. 2022;12(1</strong><strong>2</strong><strong>):</strong><strong>344</strong><strong>-</strong><strong>356</strong><strong>. eISSN 2391</strong><strong>-8306. DOI </strong><strong>http://dx.doi.org/10.12775/JEHS.2022.12.12.05</strong><strong>2</strong> <strong>https://apcz.umk.pl/JEHS/article/view/4</strong><strong>2634</strong> <strong>https://zenodo.org/record/7650272</strong
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11

POPOVYCH, Andriy, Vitaliy FIL, Sofiya RUZHYLO, Nataliya ZAKALYAK, Xawery ŻUKOW, and Dariya POPOVYCH. "Comparative study of the attributive effects of fresh and canned Naftussya water." Journal of Education, Health and Sport 13, no. 4 (2023): 142–49. https://doi.org/10.12775/JEHS.2023.13.04.015.

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<strong>POPOVYCH, Andriy, FIL, Vitaliy, RUZHYLO, Sofiya, ZAKALYAK, Nataliya, ŻUKOW, Xawery &amp; POPOVYCH, Dariya. Comparative study of the attributive effects of fresh and canned Naftussya water</strong><strong>.</strong>&nbsp;<strong>Journal of Education, Health and Sport. 202</strong><strong>3</strong><strong>;1</strong><strong>3</strong><strong>(</strong><strong>4</strong><strong>):</strong><strong>142-149.</strong><strong>&nbsp;eISSN 2391-8306. DOI </strong><strong>http://dx.doi.org/10.12775/JEHS.2023.13.04.01</strong><strong>5</strong> <strong>https://apcz.umk.pl/JEHS/article/view/4</str
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12

Popovych, Igor L., Walery A. Zukow, Vitalii M. Fil, et al. "The interaction of synbiotic of the environment and the endoecosystem as one of the mechanisms of action of balneotherapy." European Journal of Clinical and Experimental Medicine 21, no. 2 (2023): 315–23. http://dx.doi.org/10.15584/ejcem.2023.2.26.

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Introduction and aim. Drinking mineral waters are one of the environmental factors that affect the condition of the human body. Of particular interest are therapeutic waters of the Naftussya type, which contain autochthonous microbes and organic oil-like substances and can be considered as a kind of ecosystem. On the other hand, gastrointestinal tract also is an ecosystem that associates a resident microbiota and cells of various phenotypes lining the epithelial wall. We assumed that one of the mechanisms of the therapeutic effect of Naftussya water is the interaction of external and internal
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13

Gozhenko, Anatoliy, Myroslava Hrytsak, Dariya Popovych, Nataliya Badiuk, and Xawery Żukow. "“Myroslava” and “Khrystyna” drinking mineral waters modulate the state of neuroendocrine-immune complex and metabolism in patients of Truskavets’ spa." Journal of Education, Health and Sport 12, no. 3 (2022): 11–23. http://dx.doi.org/10.12775/jehs.2022.12.03.001.

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Background. Earlier in an experiment on rats we showed that newly created sulfate-chloride sodium-magnesium drinking mineral waters "Myroslava" and "Khrystyna" of Truskavets’ spa has a significant modulating effects on the parameters of metabolism and the autonomic nervous, endocrine and immune systems. Adhering to the principle "Ex experimento ad clinic", we continued research in this direction with the participation of patients of the resort. We showed that these mineral waters have favorable effects on metabolic, HRVs, EEGs, endocrine and immune parameters. This article presents an integrat
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14

Popovych, Igor, Anatoliy Gozhenko, Myroslava Hrytsak, Dariya Popovych, Nataliya Badiuk, and Walery Zukow. "Peculiarities of modulating effects of “Myroslava” and “Khrystyna” mineral waters on neuroendocrine-immune complex and metabolism in patients of Truskavets’ spa." Journal of Education, Health and Sport 12, no. 3 (2022): 53–66. http://dx.doi.org/10.12775/jehs.2022.12.03.005.

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Background. Earlier we found effects on the neuroendocrine-immune complex and metabolism, which are common to the mineral waters "Myroslava" and "Khrystyna", instead different from the effects of Naftussya water. The purpose of this article is to find the specific effects of these waters. Materials and Methods. The object of clinical-physiological observation were 22 men aged 23-70 years, who underwent rehabilitation treatment of chronic cholecystitis and pyelonephritis in remission in the Truskavets’ spa. The examination was performed twice, before and after a 7-10-day course of balneotherapy
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15

Popovych, Igor. "Similarity effects of two types of adaptogens (transcutaneous electrical stimulation with the device “VEB” ® and using of bioactive Naftussya water) on the human body." Journal of Education, Health and Sport 12, no. 4 (2022): 213–58. http://dx.doi.org/10.12775/jehs.2022.12.04.019.

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Background. The studies of the Truskavetsian Scientific School of Balneology have shown that both the Naftussya bioactive water and the standard balneotherapy complex (Naftussya drink, ozokerite applications, mineral baths) exhibit the properties of adaptogens, similar to such ginseng and phytocompositions. At the same time, in the process of researching the influence of devices for transcutaneous electrical stimulation on the human body, we found that changes in the parameters of the neuro-endocrine-immune complex and metabolism also have an adaptogenic character. The purpose of this study is
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16

Popovych, Igor L. "Similarity effects of two types of adaptogens (transcutaneous electrical stimulation with the device "VEB" ® and using of bioactive Naftussya water) on the human body." Journal of Education, Health and Sport 12, no. 8 (2022): 213–58. https://doi.org/10.12775/JEHS.2022.12.04.019.

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<strong>Popovych Igor</strong> <strong>L</strong><strong>.</strong> <strong>Similarity effects of two types of adaptogens (transcutaneous electrical stimulation with the device &ldquo;VEB&rdquo; &reg; and using of bioactive Naftussya water) on the human body</strong><strong>. Journal of Education, Health and Sport. 2022;12(4):2</strong><strong>13</strong><strong>-2</strong><strong>58.</strong><strong> eISSN 2391-8306. DOI </strong><strong>http://dx.doi.org/10.12775/JEHS.2022.12.04.01</strong><strong>9</strong> <strong>https://apcz.umk.pl/JEHS/article/view/JEHS.2022.12.04.01</strong><strong>9</
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17

POPOVYCH, Andriy, Sofiya RUZHYLO, Nataliya ZAKALYAK, Dariya POPOVYCH, and Xawery ŻUKOW. "Comparative study of the effects on the microbiota and leukocyturia of fresh and canned Naftussya water." Quality in Sport 8, no. 4 (2022): 67–72. https://doi.org/10.12775/QS.2022.08.04.007.

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<strong>POPOVYCH, Andriy, RUZHYLO, Sofiya, ZAKALYAK, Nataliya, POPOVYCH, Dariya &amp; ŻUKOW,&nbsp;Xawery. Comparative study of the effects on the microbiota and leukocyturia of fresh and canned Naftussya water</strong><strong>. Quality in Sport. 2022;8(4):</strong><strong>67</strong><strong>-</strong><strong>72</strong><strong>. eISSN 2450-3118. DOI </strong><strong>https://dx.doi.org/10.12775/QS.2022.08.04.00</strong><strong>7</strong> <strong>https://apcz.umk.pl/QS/article/view/41</strong><strong>639</strong> &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; <strong>The</strong>&nbsp;<strong>journal</stron
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18

Popovych, Igor, Anatoliy Gozhenko, Myroslava Hrytsak, et al. "General non-specific effects of balneofactors of Truskavets’ spa on parameters of neuroendocrine regulation, metabolism, immunity and microbiota in patients with chronic pyelonephritis and cholecystitis." Journal of Education, Health and Sport 12, no. 1 (2022): 368–84. http://dx.doi.org/10.12775/jehs.2022.12.01.032.

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Background. Earlier in experiments on rats, it was shown that drinking mineral water, regardless of their mineralization and chemical composition, have similar (nonspecific) course effects on a number of parameters of metabolism and neuroendocrine-immune complex. The aim of this study is to identify such parameters in patients of Truskavets’ spa who received complex drinking balneotherapy. Materials and Methods. The object of clinical-physiological observation were 34 men aged 23-70 years, who underwent rehabilitation treatment of chronic cholecystitis and pyelonephritis in remission. The exam
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19

Popovych, Andriy I. "Features of the immunotropic effects of partial components of the balneotherapeutic complex of SPA Truskavets'." Journal of Education, Health and Sport 8, no. 12 (2018): 919–35. https://doi.org/10.5281/zenodo.2577370.

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<strong>Popovych Andriy I. </strong><strong>Features of</strong>&nbsp;<strong>the immunotropic effects of partial components of the balneotherapeutic complex of SPA Truskavets&rsquo;</strong><strong>. Journal of Education, Health and Sport. 2018;8(1</strong><strong>2</strong><strong>):</strong><strong>919</strong><strong>-</strong><strong>935</strong><strong>. eISNN 2391-8306. DOI</strong>&nbsp;<strong>http://dx.doi.org/10.5281/zenodo.2577370</strong> <strong>http://ojs.ukw.edu.pl/index.php/johs/article/view/66</strong><strong>30</strong> <strong>https://pbn.nauka.gov.pl/sedno-webapp/works/905
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20

Ruzhylo, Sofiya, Nataliya Zakalyak, Dariya Popovych, et al. "Thyrotropic effects of balneotherapy in Truskavets’ spa and their endocrine, vegetative and metabolic accompaniments." Journal of Education, Health and Sport 12, no. 4 (2022): 94–104. http://dx.doi.org/10.12775/jehs.2022.12.04.008.

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Background. Previous studies of the Truskavetsian Scientific School of Balneology have studied the effects of course use of bioactive water Naftussya - the main therapeutic factor of the spa - on plasma levels of thyroid hormones in males and females healthy rats and women with thyroid hyperplasia. In men with chronic cholecystitis, the immediate thyrotropic effects of a single use of Naftussya water have been studied. The aim of this study is thyrotropic effects of balneotherapy in Truskavets’ spa and their endocrine, vegetative and metabolic accompaniments in men and women with chronic chole
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21

Zukow, Walery, and Igor Popovych. "The effect of Hydrogen-rich „Truskavetska” bottled water on the swimming stress test in female rats." Journal of Education, Health and Sport 72 (December 26, 2024): 57303. https://doi.org/10.12775/jehs.2024.72.57303.

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Background and aim. Despite the use of drinking hydrogen rich water both in clinical and sports medicine, further research into the mechanisms of its beneficial effect remains relevant. We found that both Naftussya bioactive water per se and combined balneotherapy have an ambiguous effect on physical performance. It was also found that the preventive use of “Truskavetska” bottled water, the chemical composition of which is somewhat similar to that of Naftussya bioactive water, has both similar and different effects on the post-stress parameters of rats. We set ourselves the goal of finding out
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22

Savytskyi, Ivan, Walery Zukow, and Igor Popovych. "Amelioration of the “Truskavetska” bottled water by hydrogen-riching." Journal of Education, Health and Sport 78 (February 26, 2025): 59051. https://doi.org/10.12775/jehs.2025.78.59051.

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Background and aim. The “Truskavetska” bottled water (TW) is officially classified as table water and is not considered medicinal. Recently, it rats experiment we found that enrichment of TW with Hydrogen generally has a favorable effect on its stress-limiting capacity, associated with antioxidant activity. We hypothesized that enrichment of TW with Hydrogen may increase its physiological/therapeutical activity, in particular in relation to patients with chronic pyelonephritis. Testing this hypothesis was the aim of this study. Material and methods. The object of observation were 22 men with c
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23

Hrytsak, Myroslava, Dariya Popovych, Sofiya Ruzhylo, Nataliya Zakalyak, and Walery Zukow. "Neuro-endocrine mechanism of specific balneoeffects of sulfate-chloride sodium-magnesium mineral waters." Journal of Education, Health and Sport 12, no. 3 (2022): 274–82. http://dx.doi.org/10.12775/jehs.2022.12.03.023.

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Background. Earlier we showed that the newly created sulfate-chloride sodium-magnesium drinking mineral waters “Myroslava” (5 g/L) and “Khrystyna” (10 g/L) have favorable effects on neuroendocrine-immune complex and metabolism of patients with their violations. At the same time, the influence of both waters on one constellation of parameters is similar, despite the twofold difference in mineralization, while on the other constellation it is different. The aim of this study was to elucidate the neuroendocrine mechanism of specific effects. Materials and Methods. The object of clinical-physiolog
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24

Hrytsak, Myroslava V., Dariya V. Popovych, Nataliya S. Badiuk, Ivanna I. Hrytsan, and Xawery Zukow. "Comparative study of the effects on the EEG of drinking monotherapy with Naftussya water and therapy supplemented with "Myroslava" and "Khrystyna" mineral waters." Journal of Education, Health and Sport 12, no. 2 (2022): 141–50. https://doi.org/10.12775/JEHS.2022.12.02.016.

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<strong>Hrytsak</strong>&nbsp;<strong>Myroslava V., Popovych Dariya V., Badiuk Nataliya S., Hrytsan Ivanna I., Zukow</strong>&nbsp;<strong>Xawery</strong><strong>. </strong><strong>Comparative study of the effect</strong><strong>s</strong><strong>&nbsp;on the EEG of drinking monotherapy with Naftussya water and therapy supplemented with </strong><strong>&ldquo;</strong><strong>Myroslava&rdquo; and &ldquo;Khrystyna&rdquo; mineral waters</strong><strong>.</strong>&nbsp;<strong>Journal of Education, Health and Sport. 2022;12(2):</strong><strong>141</strong><strong>-</strong><strong>150</strong><s
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25

Hrytsak, Myroslava V., Dariya V. Popovych, Nataliya S. Badiuk, Ivanna I. Hrytsan, and Xawery Żukow. "Comparative study of the effect on the neuroendocrine-immune complex and metabolism of drinking monotherapy with Naftussya water and therapy supplemented with "Myroslava" and "Khrystyna" mineral waters." Journal of Education, Health and Sport 12, no. 1 (2022): 355–67. https://doi.org/10.12775/JEHS.2022.12.01.031.

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<strong>Hrytsak</strong>&nbsp;<strong>Myroslava V.</strong><strong>,</strong><strong>&nbsp;Popovych</strong>&nbsp;<strong>Dariya V.,</strong><strong>&nbsp;Badiuk</strong><strong>&nbsp;Nataliya S.,</strong><strong>&nbsp;Hrytsan</strong><strong>&nbsp;Ivanna&nbsp;I.,</strong>&nbsp;<strong>Ż</strong><strong>ukow</strong>&nbsp;<strong>Xawery</strong><strong>. </strong><strong>Comparative study of the effect on the neuroendocrine-immune complex and metabolism of drinking monotherapy with Naftussya water and therapy supplemented with &ldquo;Myroslava&rdquo; and &ldquo;Khrystyna&rdquo; mineral waters<
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26

Struk, Zoryana D., Oksana I. Mel'nyk, Walery Zukow, and Igor L. Popovych. "The diversity of immune reactions to balneotherapy and their accompaniments." Journal of Education, Health and Sport 9, no. 11 (2019): 349–73. https://doi.org/10.5281/zenodo.3666932.

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<strong>Struk Zoryana D.</strong><strong><sup>1</sup></strong><strong>, Mel&rsquo;nyk Oksana I.</strong><strong><sup>2</sup></strong><strong>, Zukow Walery</strong><strong><sup>3</sup></strong><strong>, Popovych Igor L.</strong><strong><sup>1,4</sup></strong><strong>.</strong>&nbsp;<strong>The diversity of immune reactions to balneotherapy and their accompaniments</strong><strong>. </strong><strong>Journal of Education, Health and Sport. 2019;9(11):</strong><strong>349-373</strong><strong>. eISSN 2391-8306. DOI </strong><strong>http://dx.doi.org/10.12775/JEHS.2019.09.11.0</strong><strong>33</s
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27

Korda, Mykhaylo, Anatoliy Gozhenko, Oksana Fihura, Dariya Popovych, Xawery Żukow, and Igor Popovych. "Relationships between plasma levels of main adaptogene hormones and EEG & HRV parameters at human with dysadaptation." Journal of Education, Health and Sport 11, no. 12 (2021): 492–512. http://dx.doi.org/10.12775/jehs.2021.11.12.040.

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Background. The immunoneuroendocrinology became the foundation of the Truskavetsian Scientific School of Balneology. The focus of research was on the relationships between EEG and HRV parameters, EEG&amp;HRV and leukocytogram, phagocytosis, cellular and humoral immunity as well as between changes in these parameters under the influence of adaptogenic factors Truskavets’ spa. The purpose of this study is relationships between plasma levels of major adaptogene hormones and EEG&amp;HRV parameters at human with dysadaptation. Materials and Methods. The object of observation were 10 women 33-76 y a
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28

Popovych, Igor L., Anatoliy I. Gozhenko, Myroslava V. Hrytsak, Dariya V. Popovych, Nataliya S. Badiuk, and Walery Zukow. "Peculiarities of modulating effects of "Myroslava" and "Khrystyna" mineral waters on neuroendocrine-immune complex and metabolism in patients of Truskavets' spa." Journal of Education, Health and Sport 12, no. 3 (2022): 53–66. https://doi.org/10.12775/JEHS.2022.12.03.005.

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<strong>Popovych</strong>&nbsp;<strong>Igor L., Gozhenko Anatoliy I., Hrytsak Myroslava V., Popovych</strong>&nbsp;<strong>Dariya V., Badiuk Nataliya S., Zukow Walery</strong><strong>. </strong><strong>Peculiarities of modulating effects of &ldquo;Myroslava&rdquo; and &ldquo;Khrystyna&rdquo; mineral waters on neuroendocrine-immune complex and metabolism in patients of Truskavets&rsquo; spa</strong><strong>.</strong>&nbsp;<strong>Journal of Education, Health and Sport. 2022;12(</strong><strong>3</strong><strong>):</strong><strong>53-66.</strong><strong>&nbsp;eISSN 2391-8306. DOI </strong><stron
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29

Bombushkar, Igor, Anatoliy Gozhenko, Ivan Savytskyi, et al. "Phytotea “ATINE” has beneficial effects on some neural, endocrine, immune, metabolic and biophysics variables in patients with maladaptation." Journal of Education, Health and Sport 82 (June 23, 2025): 62835. https://doi.org/10.12775/jehs.2025.82.62835.

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Background and aim. Earlier we shown that phytotea “ATINE” enhances the immunomodulatory effect of adaptogenic factors of the Truskavets’ Spa in patients after radical treatment of oncological pathology. It is known that the main component of the balneotherapy complex of the Truskavets’ Spa – Naftussya bioactive water (NBAW) – has its own modulating effect on the parameters of the neuro-endocrine-immune complex, metabolism, acupuncture and biophotonics. The purpose of this study is to find out how the combined use of NBAW with ATINE will affect such effects as well as to estimate the essential
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30

Popovych, Andriy I. "Features of the neurotropic effects of partial components of the balneotherapeutic complex of SPA Truskavets'." Journal of Education, Health and Sport 9, no. 1 (2019): 396–409. https://doi.org/10.5281/zenodo.2582083.

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<strong><strong>Popovych Andriy I</strong></strong><strong><strong>. Features of the neurotropic effects of partial components of the balneotherapeutic complex of SPA Truskavets&rsquo;. Journal of Education, Health and Sport. 2019;9(1):396-4</strong></strong><strong><strong>09</strong></strong><strong><strong>. eISNN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.2582072</strong></strong> <strong><strong>http://ojs.ukw.edu.pl/index.php/johs/article/view/6</strong></strong><strong><strong>6</strong></strong><strong>44</strong> <strong>https://pbn.nauka.gov.pl/sedno-webapp/works/906339</strong>
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31

Gozhenko, Anatoliy I., Myroslava V. Hrytsak, Dariya V. Popovych, Nataliya S. Badiuk, and Xawery Żukow. ""Myroslava" and "Khrystyna" drinking mineral waters modulate the state of neuroendocrine-immune complex and metabolism in patients of Truskavets' spa." Journal of Education, Health and Sport 12, no. 3 (2022): 11–23. https://doi.org/10.12775/JEHS.2022.12.03.001.

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<strong>Gozhenko Anatoliy I., Hrytsak Myroslava V., Popovych Dariya V., Badiuk Nataliya S., Żukow Xawery</strong><strong>. &ldquo;Myroslava&rdquo; and &ldquo;Khrystyna&rdquo; drinking mineral waters modulate the state of neuroendocrine-immune complex and metabolism in patients of Truskavets&rsquo; spa</strong><strong>.</strong><strong> Journal of Education, Health and Sport. 2022;12(</strong><strong>3</strong><strong>):</strong><strong>11-23</strong><strong>. eISSN 2391-8306. DOI </strong><strong>http://dx.doi.org/10.12775/JEHS.2022.12.0</strong><strong>3</strong><strong>.0</strong><strong>01<
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32

Popovych, Igor L., Anatoliy I. Gozhenko, Myroslava V. Hrytsak, et al. "General non-specific effects of balneofactors of Truskavets' spa on parameters of neuroendocrine regulation, metabolism, immunity and microbiota in patients with chronic pyelonephritis and cholecystitis." Journal of Education, Health and Sport 12, no. 1 (2022): 368–84. https://doi.org/10.12775/JEHS.2022.12.01.032.

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<strong>Popovych</strong>&nbsp;<strong>Igor L., Gozhenko Anatoliy I., Hrytsak Myroslava V., Popovych Dariya V., Korolyshyn Tetyana A.,</strong><strong>&nbsp;Kovbasnyuk&nbsp;Marta&nbsp;M.</strong><strong>, Zukow Walery</strong><strong>. </strong><strong>General non-specific effects of balneofactors of Truskavets&rsquo; spa on parameters of neuroendocrine regulation, metabolism, immunity and microbiota in patients with chronic pyelonephritis and cholecystitis</strong><strong>.</strong>&nbsp;<strong>Journal of Education, Health and Sport. 2022;12(1):</strong><strong>368</strong><strong>-</strong>
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33

Marfiyan, O. M., T. A. Korolyshyn, L. G. Barylyak, et al. "Neuroendocrine-immune and metabolic accompaniments of cholecystokinetic effects of balneotherapy on SPA Truskavets’." Journal of Education, Health and Sport 5, no. 5 (2015): 21–30. https://doi.org/10.5281/zenodo.17307.

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<strong>Marfiyan O</strong> <strong>M, Korolyshyn T</strong> <strong>A, Barylyak L</strong> <strong>G, </strong><strong>Kovbasnyuk M M, </strong><strong>Yavors&rsquo;kyi O</strong> <strong>V,</strong> <strong>Zukow W,</strong> <strong>Popovych I</strong> <strong>L</strong><strong>. </strong><strong>Neuroendocrine-immune and metabolic accompaniments of cholecystokinetic effects of balneotherapy on SPA Truskavets&rsquo;</strong><strong>. </strong><strong>Journal of Education, Health and Sport. </strong><strong>2015;5(5):21-30. ISSN 2391-8306. DOI: </strong><strong>10.5281/zenodo.17307</strong> <
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34

Ruzhylo, Sofiya V., Nataliya R. Zakalyak, Dariya V. Popovych, et al. "Thyrotropic effects of balneotherapy in Truskavets' spa and their endocrine, vegetative and metabolic accompaniments." Journal of Education, Health and Sport 12, no. 4 (2022): 94–104. https://doi.org/10.12775/JEHS.2022.12.04.008.

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<strong>Ruzhylo</strong><strong> </strong><strong>Sofiya</strong><strong> </strong><strong>V</strong><strong>., </strong><strong>Zakalyak</strong><strong> </strong><strong>Nataliya</strong><strong> </strong><strong>R</strong><strong>., </strong><strong>Popovych</strong><strong> </strong><strong>Dariya</strong><strong> </strong><strong>V</strong><strong>., </strong><strong>Kikhtan</strong><strong> </strong><strong>Volodymyr</strong><strong> </strong><strong>V</strong><strong>.,</strong><strong> Seniv Teodor S.</strong><strong>, </strong><strong>Novak</strong><strong> </strong><strong>Oksana</st
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35

Marfiyan, Olena M., and Walery Zukow. "Relationships between parameters of gall-bladder motility and neuroendocrine-immune complex and metabolism in men with chronic cholecystitis and pyelonephritis." Journal of Education, Health and Sport 5, no. 12 (2015): 434–49. https://doi.org/10.5281/zenodo.35660.

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<strong>Marfiyan Olena M</strong><strong>, </strong><strong>Zukow Walery. Relationships between p</strong><strong>a</strong><strong>rame</strong><strong>t</strong><strong>e</strong><strong>rs</strong> <strong>of gall-bladder motility and neuroendocrine-immune complex and metabolism in</strong><strong> men with </strong><strong>chronic cholecystitis and pyelonephritis. </strong><strong>Journal of Education, Health and Sport. </strong><strong>2015;5(12):434-449. ISSN 2391-8306. DOI</strong> <strong>http://dx.doi.org/10.5281/zenodo.35660</strong> <strong>http://ojs.ukw.edu.pl/index.php/johs/artic
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36

Kyrylenko, Iryna G., Igor-Severyn S. Flyunt, Vitaliǐ M. Fil', Walery Zukow, and Igor L. Popovych. "Changes in electrokinetic index of buccal epithelium correlated with changes in some parameters of immunity and fecal microbiocenosis." Journal of Education, Health and Sport 8, no. 10 (2018): 168–74. https://doi.org/10.5281/zenodo.1471789.

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<strong>Kyrylenko Iryna G, Flyunt Igor-Severyn S, Fil&rsquo; Vitaliǐ M, Zukow Walery, </strong><strong>Popovych Igor L. Changes in electrokinetic index of buccal epithelium correlated with changes in some parameters of immunity and fecal microbiocenosis. </strong><strong>Journal of Education, Health and Sport. 2018;8(10):168-174. eISNN 2391-8306. DOI </strong><strong>http://dx.doi.org/10.5281/zenodo.1471789</strong> <strong>http://ojs.ukw.edu.pl/index.phpohs/article/view/62</strong><strong>2</strong><strong>7</strong> <strong>https://pbn.nauka.gov.pl/sedno-webapp/works/884805</strong> &nbsp; &
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37

Hrytsak, Myroslava V., Dariya V. Popovych, Sofiya V. Ruzhylo, Nataliya R. Zakalyak, and Walery Zukow. "Neuro-endocrine mechanism of specific balneoeffects of sulfate-chloride sodium-magnesium mineral waters." Journal of Education, Health and Sport 12, no. 3 (2022): 274–82. https://doi.org/10.12775/JEHS.2022.12.03.023.

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<strong>Hrytsak</strong>&nbsp;<strong>Myroslava V.,</strong><strong>&nbsp;Popovych</strong><strong>&nbsp;Dariya V.,</strong>&nbsp;<strong>Ruzhylo</strong><strong>&nbsp;Sofiya</strong>&nbsp;<strong>V</strong><strong>.,</strong>&nbsp;<strong>Zakalyak</strong>&nbsp;<strong>Nataliya</strong>&nbsp;<strong>R</strong><strong>.,</strong><strong>&nbsp;Zukow</strong>&nbsp;<strong>Walery</strong><strong>. </strong><strong>Neuro-endocrine mechanism of specific balneoeffects of sulfate</strong><strong>-chloride sodium-magnesium</strong><strong>&nbsp;mineral waters</strong><strong>.</strong>&nbsp;<strong>Jo
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38

Mel'nyk, Oksana I., Zoryana D. Struk, Walery Zukow, and Igor L. Popovych. "Vegetative, endocrine and metabolic accompaniments of individual immune responses to adaptogenic balneotherapy." Journal of Education, Health and Sport 9, no. 12 (2019): 207–29. https://doi.org/10.5281/zenodo.3724816.

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<strong>Mel</strong><strong>&rsquo;</strong><strong>nyk Oksana</strong>&nbsp;<strong>I</strong><strong>.,</strong><strong>&nbsp;Struk Zoryana</strong>&nbsp;<strong>D</strong><strong>.,</strong><strong>&nbsp;Zukow Walery, Popovych Igor L.</strong><strong>&nbsp;Vegetative, endocrine and metabolic accompaniments</strong><strong>&nbsp;of individual immune responses to adaptogenic balneotherapy</strong><strong>. </strong><strong>Journal of Education, Health and Sport. 20</strong><strong>19</strong><strong>;</strong><strong>9</strong><strong>(</strong><strong>12</strong><strong>):</strong><strong>20
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39

Korda, Mykhaylo, Anatoliy Gozhenko, Oksana Fihura, Dariya Popovych, Xawery Żukow, and Igor Popovych. "Relationships between plasma levels of main adaptogene hormones and EEG & HRV parameters at human with dysadaptation." Journal of Education, Health and Sport 11, no. 12 (2021): 492–512. https://doi.org/10.12775/JEHS.2021.11.12.040.

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<strong>Korda, Mykhaylo, Gozhenko, Anatoliy, Fihura, Oksana, Popovych, Dariya, Żukow, Xawery</strong><strong>, </strong><strong>Popovych, Igor</strong><strong>. </strong><strong>Relationships between plasma levels of main adaptogene hormones and EEG &amp; HRV parameters at human with dysadaptation</strong><strong>. Journal of Education, Health and Sport. 2021;11(12):</strong><strong>4</strong><strong>92-51</strong><strong>2</strong><strong>. </strong><strong>eISSN 2391-8306. DOI </strong><strong>http://dx.doi.org/10.12775/JEHS.2021.11.12.0</strong><strong>40</strong> <strong>https://apcz.umk.p
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40

Popovych, Igor L., Nadiya O. Sydoruk, Anatoliy I. Gozhenko, and Walery Zukow. "Modulating neuro-endocrine effects of bioactive water Naftussya from layers Truskavets' and Pomyarky at humans with dysfunction of neuro-endocrine-immune complex." February 28, 2017. https://doi.org/10.5281/zenodo.437582.

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<strong>Popovych Igor L, Sydoruk Nadiya O, Gozhenko Anatoliy I, Zukow Walery. </strong><strong>Modulating neuro-endocrine effects of bioactive water Naftussya from layers Truskavets’ and Pomyarky at humans with dysfunction of neuro-endocrine-immune complex. </strong><strong>Journal of Education, Health and Sport. 2017;7(2):465-478. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.437582</strong> <strong>http://ojs.ukw.edu.pl/index.php/johs/article/view/4349</strong> <strong>The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 1223 (26
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41

Gozhenko, Anatoliy I., Nadiya O. Sydoruk, Valeriy Ye Babelyuk, et al. "Modulating effects of bioactive water Naftussya from layers Truskavets' and Pomyarky on some metabolic and biophysic parameters at humans with dysfunction of neuro-endocrine-immune complex." December 31, 2016. https://doi.org/10.5281/zenodo.238225.

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<strong>Gozhenko Anatoliy I, Sydoruk Nadiya O, Babelyuk Valeriy Ye, Dubkova Galyna I, Flyunt Viktor R, Hubyts’kyi Viktor Yo, Zukow Walery, Barylyak Liliya G, Popovych Igor L. Modulating effects of bioactive water Naftussya from layers Truskavets’ and Pomyarky on some metabolic and biophysic parameters at humans with dysfunction of neuro-endocrine-immune complex. </strong><strong>Journal of Education, Health and Sport. </strong><strong>2016;6(12):826-842. eISSN 2391-8306. DOI </strong><strong>http://dx.doi.org/10.5281/zenodo.238225</strong> <strong>http://ojs.ukw.edu.pl/index.php/johs/article/v
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42

Popovych, I. L. "BIOACTIVE «NAFTUSSYA» WATER AND PHYTOCOMPOSITION "BALM TRUSKAVETS" CAUSES SIMILAR ADAPTOGENIC EFFECTS ON SOME PARAMETERS OF THE HUMAN BODY = БІОАКТИВНА ВОДА «НАФТУСЯ» ТА ФІТОКОМПОЗИЦІЯ «БАЛЬЗАМ ТРУСКАВЕЦЬКИЙ» СПРИЧИНЯЮТЬ ПОДІБНІ АДАПТОГЕННІ ЕФЕКТИ НА ДЕЯКІ ПАРАМЕТРИ ОРГАНІЗМУ ЛЮДИНИ". 13 лютого 2023. https://doi.org/10.5281/zenodo.7617705.

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Popovych I. L. BIOACTIVE &laquo;NAFTUSSYA&raquo; WATER AND PHYTOCOMPOSITION &ldquo;BALM TRUSKAVETS&rdquo; CAUSES SIMILAR ADAPTOGENIC EFFECTS ON SOME PARAMETERS OF THE HUMAN BODY = БІОАКТИВНА ВОДА &laquo;НАФТУСЯ&raquo; ТА ФІТОКОМПОЗИЦІЯ &laquo;БАЛЬЗАМ ТРУСКАВЕЦЬКИЙ&raquo; СПРИЧИНЯЮТЬ ПОДІБНІ АДАПТОГЕННІ ЕФЕКТИ НА ДЕЯКІ ПАРАМЕТРИ ОРГАНІЗМУ ЛЮДИНИ \\ Актуальні проблеми транспортної медицини / Actual problems of transport medicine / 2023;1-2(71-72):121-137. ISSN 1818-9385 DOI http://dx.doi.org/10.5281/zenodo.7617705 http://aptm.org.ua &nbsp; &nbsp; УДК 612.461.25+616-008.9]:615.838 DOI http://dx.d
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43

Sydoruk, Nadiya O., and Walery Zukow. "Comparative investigation of immediate effects on neuro-endocrine-immune complex of bioactive water Naftussya from layers Truskavets’, Pomyarky and Skhidnyts’a. Communication 1. Generic effects." August 8, 2016. https://doi.org/10.5281/zenodo.59762.

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<strong>Sydoruk Nadiya O, </strong><strong>Zukow W</strong><strong>alery. Comparative investigation of immediate effects on neuro-endocrine-immune complex of bioactive water Naftussya from layers Truskavets&rsquo;, Pomyarky and Skhidnyts&rsquo;a. Communication 1. Generic effects. </strong><strong>Journal of Education, Health and Sport. 2016;6(8):85-84. eISSN 2391-8306. DOI </strong><strong>http://dx.doi.org/10.5281/zenodo.59762</strong> <strong>http://ojs.ukw.edu.pl/index.php/johs/article/view/3734</strong> &nbsp; &nbsp; &nbsp; <strong>The journal has had 7 points in Ministry of Science and Hi
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44

Flyunt, Viktor R., Igor-Severyn S. Flyunt, Vitalij M. Fil', et al. "Relationships between caused by drinking of bioactive water Naftussya changes in urine lithogenicity and neuro-humoral-immune factors in humans with theirs abnormalities." January 28, 2017. https://doi.org/10.5281/zenodo.261918.

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<strong>Flyunt Viktor R, Flyunt Igor-Severyn S, Fil’ Vitalij M, </strong><strong>Kovbasnyuk Marta M, Hryvnak Rostyslav F, Popel Svitlana L, </strong><strong>Zukow W</strong><strong>alery. Relationships between caused by drinking of</strong> <strong>bioactive water Naftussya changes in urine lithogenicity and </strong><strong>neuro-</strong><strong>humoral-</strong><strong>immune </strong><strong>factors in humans</strong> <strong>with theirs abnormalities. </strong><strong>Journal of Education, Health and Sport. </strong><strong>2017;7(3):11-30. eISSN 2391-8306. DOI </strong><strong>http://dx.
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45

Sydoruk, Nadiya O., Anatoliy I. Gozhenko, and Walery Zukow. "Modulating effects of bioactive water Naftussya from layers Truskavets' and Pomyarky on neuro-endocrine-immune complex and metabolism at rats exposed to acute stress." January 1, 2017. https://doi.org/10.5281/zenodo.227087.

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<strong>Sydoruk Nadiya O, Gozhenko Anatoliy I, Zukow Walery. Modulating effects of bioactive water Naftussya from layers Truskavets’ and Pomyarky on neuro-endocrine-immune complex and metabolism at rats exposed to acute stress. </strong><strong>Journal of Education, Health and Sport. 2016;</strong><strong>6(11):715-730. eISSN 2391-8306. DOI </strong><strong>http://dx.doi.org/10.5281/zenodo.227087</strong> <strong>http://ojs.ukw.edu.pl/index.php/johs/article/view/4125</strong> <strong>The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 755
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46

Barylyak, L. G., Yu Z. Kruhliy, W. Zukow, O. R. Yanchiy, and I. L. Popovych. "Indicators, distinctive for women with different ovarian status and different responses streslimiting effect of bioactive water Naftussya SPA Truskavets’." March 26, 2015. https://doi.org/10.5281/zenodo.16398.

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<strong>Barylyak L G</strong><strong>, </strong><strong>Kruhliy Yu Z</strong><strong>, </strong><strong>Zukow W</strong><strong>, </strong><strong>Yanchiy O R</strong><strong>, </strong><strong>Popovych I L. </strong><strong>Indicators, distinctive for women with different ovarian status and different responses streslimit</strong><strong>ing effect of</strong><strong> bioactive water Naftus</strong><strong>s</strong><strong>ya</strong><strong> SPA Truskavets&rsquo;. </strong><strong>Journal of Education, Health and Sport. </strong><strong>2015;5(3):247-258. ISSN 2391-8306. DOI: 10.5281/zenodo.
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47

Sydoruk, Nadiya O., and Walery Zukow. "Differences between the effects of water Naftussya from fields of Truskavets' and Pomyarky on the parameters of the EEG, HRV, immunity and metabolism." January 30, 2019. https://doi.org/10.5281/zenodo.2552912.

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<strong>Sydoruk Nadiya</strong><strong> </strong><strong>O</strong><strong>, </strong><strong>Zukow Walery. </strong><strong>Differences between the effects of water </strong><strong>Naftussya</strong><strong> </strong><strong>from </strong><strong>fields of Truskavets</strong><strong>&rsquo;</strong><strong> and Pom</strong><strong>y</strong><strong>ark</strong><strong>y</strong><strong> on the parameters of the </strong><strong>EEG, HRV, immunity and metabolism</strong><strong>.</strong><strong> </strong><strong>Journal of Education, Health and Sport. 2019;9(1):</strong><strong>287</strong><
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