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Relevant bibliographies by topics / Naphthyridin

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Academic literature on the topic 'Naphthyridin'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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Journal articles on the topic "Naphthyridin"

1

Kulakov, Ivan, Mariya Matsukevich, Maxim Levin, Irina Palamarchuk, Tulegen Seilkhanov, and Alexander Fisyuk. "Synthesis of the First Representatives of Thieno[3,2-c][1,7]naphthyridine Derivatives Based on 3-Amino-6-methyl-4-(2-thienyl) pyridin-2(1H)-one." Synlett 29, no. 13 (2018): 1741–44. http://dx.doi.org/10.1055/s-0037-1610445.

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A one-pot method for obtaining novel thieno[3,2-c][1,7]naphthyridine derivatives based on the reaction of 3-amino-4-(thien-2-yl)pyridin-2(1H)-one with aromatic aldehydes in 80% phosphoric acid at 130 °C has been developed. The formation of the thieno[3,2-c][1,7]naphthyridine ring was due to the intermediate generation of the corresponding azomethine, which underwent intramolecular cyclization with electrophilic attack of the β-carbon atom of the thiophene core under Pictet–Spengler conditions. The isolated 5,7-dihydrothieno[3,2-c][1,7]naphthyridin-4(3H)-ones underwent oxidative aromatization

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Barlin, GB, and C. Jiravinyu. "Potential Antimalarials. X. Di-Mannich Bases of 4-(7'-Trifluoromethyl-1',5'-naphthyridin-4'-ylamino)phenol and N-(4'-Diethylamino-1'-methylbutyl)-7-trifluoromethyl-1,5-naphthyridin-4- amine." Australian Journal of Chemistry 43, no. 7 (1990): 1175. http://dx.doi.org/10.1071/ch9901175.

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The syntheses of some di-Mannich bases derived from 4-(7′-trifluoromethyl-1′,5′-naphthyridin-4′-ylamino) phenol and of N-(4′-diethylamino-11′-methylbutyl)-7-trifluoromethyl-1,5-naphthyridin-4- amine from 3-chloro-5-trifluoromethylpyridine via4-chloro-7- trifluoromethyl-1,5-naphthyridine are described. In tests in vitro against the FCQ-27 strain of Plasmodium falciparum these compounds were slightly less active than their 7-bromo analogues.

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Barlin, GB, and W. Tan. "Potential Antimalarials. III. N4-Substituted 7-Bromo-1,5-naphthyridin-4-amines." Australian Journal of Chemistry 38, no. 3 (1985): 459. http://dx.doi.org/10.1071/ch9850459.

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A series of new N4-substituted 7-bromo-1,5-naphthyridin-4-amines has been prepared from nicotinic acid through 3-bromo-8-chloro- 1,5- naphthyridine by nucleophilic replacement of the 8-chloro substituent with appropriate amines. Several of these compounds, namely 7-bromo-N- (4′-diethylamino-1′-methylbutyl)-1,5-naphthy-ridin-4-amine (′5-azabromoquine'), 4-(7′-bromo-1′,5′-naphthyridin-4′-ylamino)-2-(diethylamino-methyl)phenol and 7-bromo-N-(2′-diethylaminoethyl)-1,5- naphthyridin-4-amine showed significant antimalarial acivity. Apparent cures were effected when these test chemicals were injected

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Nageswara Rao, Ambala, Dara Hariprasad, and Chinthala Venkanna. "EFFICIENT SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF 3-(3-ARYL-4,5-DIHYDRO-1H-PYRAZOL-5-YL)-2- (TRIFLUOROMETHYL)-1,8-NAPHTHYRIDINES." RASAYAN Journal of Chemistry 16, no. 01 (2023): 233–39. http://dx.doi.org/10.31788/rjc.2023.1618056.

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An efficient synthesis of 3-(3-Aryl-4,5-dihydro-1H-pyrazol-5-yl)-2-(trifluoromethyl)-1,8-naphthyridines 5(a-h) was achieved by the cyclo condensation of 1-Aryl-3-(2-(trifluoromethyl)-1,8-naphthyridin-3-yl)prop-2-en-1-ones(4a-h) with hydrazine hydrate. The compounds 4(a-h) were synthesized through a three-step procedure starting from ethyl 2-(trifluoromethyl)-1,8-naphthyridine-3-carboxylate (1). Antibacterial and antifungal activities of the final compounds 5(a-h) have been screened and compound 5h exhibited significant inhibition of bacterial and fungal growth. The structures of compounds 3-5

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Ridley, AB, and WC Taylor. "Synthesis of 6-(3,4-Dimethoxyphenyl)-4-oxo-3,4-dihydrobenzo[C][2,7]naphthyridin-6-ium Chloride (Perloline Chloride)." Australian Journal of Chemistry 40, no. 3 (1987): 631. http://dx.doi.org/10.1071/ch9870631.

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Perloline was synthesized as its chloride, 6-(3,4-dimethoxypheny1)-4-oxo-3,4-dihydrobenzo-[c][2,7]naphthyridin-6-ium chloride (lb), by utilizing the photochemical rearrangement of the N-oxide (6) of 5-(3,4-dimethoxyphenyl) benzo [c][2,7]naphthyridin-4(3 H)-one (2) to 6-(3,4-dimethoxyphenyl ) benzo [c][2,7]naphthyridine-4,5(3 H,6 H)- dione (7) ( dehydroperloline), which was then selectively reduced with sodium bis( methoxyethoxy ) aluminium hydride. The naphthyridinone (2) was prepared conveniently by reaction of 2-(3,4-dimethoxypheny1)-4-methylquinoline-3-carbonitrile (4) with dimethylformamid

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KUNDENAPALLY, RAMALINGAM, RAMESH DOMALA, and B. SREENIVASULU. "Regioselective Synthesis of Novel [N-(4-Oxo-3-(2-phenyl-1,8-naphthyridin-3-yl)-thiazolidin-2-ylidene)]acetamide/benzamides and their Biological Activity." Asian Journal of Chemistry 31, no. 6 (2019): 1246–50. http://dx.doi.org/10.14233/ajchem.2019.21881.

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In an attempt to discover the new antibacterial agents to fight the bacterial infections, a series of 1,8-naphthyridine based 2-iminothiazolidin-4-one derivatives was synthesized by a straight-forward regioselective synthesis. 2-Phenyl-1,8-naphthyridin-3-amine (2) was reacted with acetyl or aroyl isothiocyantes to give the corresponding N-[(2-phenyl-1,8-naphthyridin-3-yl)carbamothioyl)]acetamide or benzamides (3a-e). Finally, the target compounds [N-(4-oxo-3-(2-phenyl-1,8-naphthyridin-3-yl)thiazolidin-2-ylidene)]acetamide or benzamides (4a-e) were obtained by the reaction of thiourea (3a-e) wi

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Oliveras, Juan Marcos, Raimon Puig de la Bellacasa, Roger Estrada-Tejedor, Jordi Teixidó, and José I. Borrell. "1,6-Naphthyridin-2(1H)-ones: Synthesis and Biomedical Applications." Pharmaceuticals 14, no. 10 (2021): 1029. http://dx.doi.org/10.3390/ph14101029.

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Naphthyridines, also known as diazanaphthalenes, are a group of heterocyclic compounds that include six isomeric bicyclic systems containing two pyridine rings. 1,6-Naphthyridines are one of the members of such a family capable of providing ligands for several receptors in the body. Among such structures, 1,6-naphthyridin-2(1H)-ones (7) are a subfamily that includes more than 17,000 compounds (with a single or double bond between C3 and C4) included in more than 1000 references (most of them patents). This review will cover the analysis of the diversity of the substituents present at positions

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K., RAJENDAR REDDY, RAMA RAO G., MOGILAIAH K., and SREENIVASULU B. "Condensed 1,8-Naphthyridines. Part-VII. Synthesis of 6H-Indeno[ 1,2-b ][1,8]- naphthyridin-6-one." Journal of Indian Chemical Society Vol. 64, Jul 1987 (1987): 443–44. https://doi.org/10.5281/zenodo.6198555.

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Department of Chemistry, Rakatiya University, Warangal-506 009 <em>Manuscript received 10 December 1986, accepted 6 July 1987</em> Condensed 1,8-Naphthyridines. Part-VII. Synthesis of 6H-Indeno[1,2-b ][1,8]- naphthyridin-6-one.

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G., RAMA RAO, MOGILAIAH K., RAJENDAR REDDY K., and SREENIVASULU B. "Substituted-1,8-naphthyridines. Part-VII. Synthesis and Biological Activity of 4-Arylazo-2-(1,8-naphthyridin-2-yl)phenols." Journal of Indian Chemical Society Vol. 64, Nov 1987 (1987): 710–12. https://doi.org/10.5281/zenodo.6254086.

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Department of Chemistry, Kakatiya University, Warangal-506 009 <em>Manuscript received 0 May 1987, accepted 18 September 1987</em> Substituted-1,8-naphthyridines. Part-VII. Synthesis and Biological Activity of 4-Arylazo-2-(1,8-naphthyridin-2-yl)phenols.

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Mogilaiah, Kaleru, Mullangi Prashanthi, Siddoju Kavitha, and Nagavelli Vasudeva Reddy. "The Synthesis of 2-(1,2,3-Triazol-2-yl)-1,8-Naphthyridines under Microwave Irradiation." Journal of Chemical Research 2005, no. 8 (2005): 523–25. http://dx.doi.org/10.3184/030823405774663255.

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An efficient and convenient method is described for the synthesis of 3-aryl-2-(4,5-dimethyl-2H-1,2,3-triazol-2-yl)-1,8-naphthyridines (4) from α-acetylacetaldoxime 3-aryl-1,8-naphthyridin-2-ylhydrazones (3) in the presence of acetic anhydride and DMF using basic alumina as solid support under microwave irradiation.

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Dissertations / Theses on the topic "Naphthyridin"

1

Bode, Matthias. "Benzo[c][2,7]naphthyridin-5-yl-amine und Benzo[h][1,6]naphthyridin-5-yl-amine." [S.l.] : [s.n.], 2006. http://deposit.ddb.de/cgi-bin/dokserv?idn=979241499.

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Wiik, Jhonny. "Naphthyridine Based Molecular Switches." Thesis, Mälardalens högskola, Akademin för hållbar samhälls- och teknikutveckling, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-15477.

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This thesis is focused on the synthesis and halogenation of 1,5-naphthyridine and 2,6-naphthyridine with the aim of finding a suitable method to synthesize mono- and bis-naphthyridine centered tridentate ligands for ruthenium complexes. Firstly the halogenated naphthyridines were synthesized, then 2-(2-thienyl)-6-ributylstannylpyridine was synthesized, and the two building blocks were coupled through a Stille cross coupling reaction. The thesis describes the synthesis of 2,6-dichloro-1,5-naphthyridine, 2-chloro-1,5-naphthyridine, 1,5-dichloro-2,6-naphthyridine and 1-chloro-2,6-naphthyridine. T

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Wormell, Paul. "The electronic spectra of some naphthyridines." Thesis, The University of Sydney, 1985. https://hdl.handle.net/2123/26866.

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This thesis reports and interprets the electronic spectra of two aromatic heterocyclic molecules: 1,8- naphthyridine and 2,7—naphthyridine. This completes the first detailed survey of the spectra of the ten naphthyridine isomers. The naphthyridines are analogues of naphthalene, and contain two nitrogen atoms in a variety of substitution pattern.

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Bailey, Andrew James. "An exploration of the solid-state architectures formed by 1,8-naphthyridine-2,7-dicarbonyl derivatives." Thesis, University of Southampton, 2011. https://eprints.soton.ac.uk/179457/.

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Building on previous studies of tape formation by dicarbonyl substituted pyridine derivatives in the solid state, it was proposed that expansion of the hydrogen bonding array from three donor-acceptor pairs to four should increase the strength of the hydrogen-bonded array. Accordingly an investigation into the 1,8-naphthyridine-2,7-dicarbonyl derivatives has now been undertaken. Following the synthesis of 1,8-naphthyridine-2,7-dicarboxylic acid, during which the solid-state structures of three key intermediates were obtained, thirty-five novel 1,8-naphthyridine-2,7-dicarboxylates and fourteen

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Devaux, Floriane. "Synthesis and AFM-based single-molecule force spectroscopy of helical aromatic oligoamide foldamers." Thesis, Bordeaux, 2018. http://www.theses.fr/2018BORD0346.

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Les foldamères sont des architectures moléculaires synthétiques repliées, inspirées par les structures et les fonctions des biopolymères naturels. Le repliement est un processus sélectionné par la nature pour contrôler la conformation de sa machinerie moléculaire afin de réaliser des tâches chimiques ou mécaniques. Durant les dix dernières années de recherche sur les foldamères, des oligomères synthétiques, capables d'adopter des conformations repliées bien définies et prévisibles, comme des hélices, ont été proposés. Les progrès récents ont montré que la synthèse chimique par étapes et le des

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尹俊偉 and Chun-wai Wan. "Spectroscopic properties and coordination chemistry of d10 metal complexes with the polypyridyl and naphthyridyl ligands." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2000. http://hub.hku.hk/bib/B31223564.

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Wan, Chun-wai. "Spectroscopic properties and coordination chemistry of d10 metal complexes with the polypyridyl and naphthyridyl ligands /." Hong Kong : University of Hong Kong, 2000. http://sunzi.lib.hku.hk/hkuto/record.jsp?B22227301.

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Buttard, Floris. "3-Vinyl-1,2,4-triazines comme plateformes bifonctionnelles pour la synthèse de nouvelles structures tétrahydro-[1,6]-naphthyridines." Thesis, Orléans, 2018. http://www.theses.fr/2018ORLE2032.

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Le développement de nouvelles méthodes de synthèse de molécules hétérocycliques originales représente un enjeu actuel majeur en chimie organique. L’objectif est de fournir de nouveaux outils chimiques pour le développement de molécules actives en chimie médicinale et/ou pour l’étude de la biologie chimique, tout en contribuant à l’exploration de l’espace chimique.Dans ce contexte, le travail effectué au cours de cette thèse de doctorat a visé à élaborer de nouvelles voies de synthèse de motifs tétrahydro-[1,6]-naphtyridines. La pierre angulaire des méthodologies développées réside dans l’utili

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Harris, Cragin K. "Synthesis and Characterization of Five New Tetrakis(N-phenylacetamidato) Dirhodium(II) Amine Complexes and One Molybdenum Cofactor Described Crystallographically." Digital Commons @ East Tennessee State University, 2015. https://dc.etsu.edu/etd/2525.

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Six new crystal structures were determined using a Rigaku Mercurcy 375/MCCD(XtaLab mini) diffractometer. The structure of a molybdenum cofactor was solved resulting in an R1 (R1 = Σ ||Fo| - |Fc|| / Σ |Fo|) of 3.61% despite the presence of a disordered DMSO molecule. New Tetrakis(N-phenylacetamidato) Dirhodium(II) complexes were synthesized and characterized. Two 2,2-cis-[Rh2(NPhCOCH3)4]•(C3H4N2)x where x= 1 or 2 were successfully crystallized and solved with R1 values below 5%. Additional studies were conducted via NMR to observe formation of both products. Three potential catalysts were synth

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Ye, Guozhong. "Synthesis and reactions of cyclic ketene-N,N-acetals." Diss., Mississippi State : Mississippi State University, 2008. http://library.msstate.edu/etd/show.asp?etd=etd-09142008-210135.

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Books on the topic "Naphthyridin"

1

Brown, D. J. The naphthyridines. Wiley, 2008.

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Taylor, Edward C., Desmond J. Brown, and Jonathan A. Ellman. Naphthyridines. Wiley & Sons, Incorporated, John, 2007.

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Taylor, Edward C., Desmond J. Brown, and Jonathan A. Ellman. Naphthyridines. Wiley & Sons, Incorporated, John, 2008.

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Chemistry of Heterocyclic Compounds, the Naphthyridines. Wiley & Sons Canada, Limited, John, 2008.

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The Chemistry of Heterocyclic Compounds, The Naphthyridines (Chemistry of Heterocyclic Compounds: A Series Of Monographs). Wiley-Interscience, 2007.

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Book chapters on the topic "Naphthyridin"

1

Dilworth, J. R., and S. Morton. "From Terpyridyl and Naphthyridine." In Inorganic Reactions and Methods. John Wiley & Sons, Inc., 2007. http://dx.doi.org/10.1002/9780470145227.ch22.

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Yadav, Sandeep, Anirudh Pratap Singh Raman, Madhur Babu Singh, Pallavi Jain, Prashant Singh, and Kamlesh Kumari. "Naphthyridine, Phthalocyanine, and Their Derivative-based Corrosion Inhibitors." In Handbook of Heterocyclic Corrosion Inhibitors. CRC Press, 2023. http://dx.doi.org/10.1201/9781003377016-6.

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Chung, John Y. L. "Development of a Practical Synthesis of Naphthyridone p38 MAP Kinase Inhibitor MK-0913." In Transition Metal-Catalyzed Couplings in Process Chemistry. Wiley-VCH Verlag GmbH & Co. KGaA, 2013. http://dx.doi.org/10.1002/9783527658909.ch04.

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Lalia-Kantouri, M., and D. M. L. Goodgame. "Laser-Raman Spectroscopy of Some Lanthanide/Hgl2 Heterometallic Complexes (HL=5,7-Dimethyl-1,8-Naphthyridine-2-OL)." In Application of Particle and Laser Beams in Materials Technology. Springer Netherlands, 1995. http://dx.doi.org/10.1007/978-94-015-8459-3_18.

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"1,7-Naphthyridine, Alkyl-1, 7-Naphthyridines, and Aryl-1, 7-Naphthyridines." In Chemistry of Heterocyclic Compounds: A Series Of Monographs. John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470181164.ch16.

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"1,5-Naphthyridine, Alkyl-1, 5-naphthyridines, and Aryl-1, 5-naphthyridines." In Chemistry of Heterocyclic Compounds: A Series Of Monographs. John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470181164.ch2.

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"1,8-Naphthyridine, Alkyl-1, 8-Naphthyridines, and Aryl-1, 8-Naphthyridines." In Chemistry of Heterocyclic Compounds: A Series Of Monographs. John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470181164.ch23.

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"1,6-Naphthyridine, Alkyl-1, 6-Naphthyridines, and Aryl-1, 6-Naphthyridines." In Chemistry of Heterocyclic Compounds: A Series Of Monographs. John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470181164.ch9.

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Shireesha, Kavati, Dr Kavitha Siddoju, and Dr Kumara Swamy Jella. "ANTIBACTERIAL, ANTIFUNGAL ACTIVITY OF NEWLY SYNTHESIZED 1, 8-NAPHTHYRIDINYL HETEROCYCLES." In Futuristic Trends in Chemical Material Sciences & Nano Technology Volume 3 Book 9. Iterative International Publishers, Selfypage Developers Pvt Ltd, 2024. http://dx.doi.org/10.58532/v3becs9p4ch3.

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Due to the utility of these composites as medicines, heterocyclic chemistry is veritably important to medicinal druggists. Multitudinous heterocyclic substances are being used as medicinal agents and are also necessary for mortal life. 1,8-Naphthyridine Derivations Are a Significant Class of Heterocyclic Chemicals Due to Their Wide Range of Natural Conduct. Numerous 1,8- naphthyridine derivations were created as a result of nalidixic acid's remarkable clinical effectiveness as an antibacterial medicine.

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DeRosa, Thomas F. "Naphthyridines." In Advances in Synthetic Organic Chemistry and Methods Reported in US Patents. Elsevier, 2006. http://dx.doi.org/10.1016/b978-008044474-1/50056-6.

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Conference papers on the topic "Naphthyridin"

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Andrighetto, Rosália, Helio G. Bonacorso, Felipe S. Stefanello, Marcos A. P. Martins, and Nilo Zanatta. "General pathways for obtainment of halo-containing 1,8- naphthyridines,1,8-naphthyridin-2(1H)-ones and their derivatives." In 15th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-15bmos-bmos2013_201368142558.

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Dhamodharan, V., S. Harikrishna, C. Jagadeeswaran, and P. I. Pradeepkumar. "G-Quadruplex DNA stabilizing agents based on 1,8-naphthyridine." In XVth Symposium on Chemistry of Nucleic Acid Components. Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 2011. http://dx.doi.org/10.1135/css201112433.

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Dotsenko, Victor, Maria Goykalova (Averyasova), Elena Chigorina, Nikolay Aksenov, Inna Aksenova, and Vladimir Strelkov. "A new approach towards thieno[2,3-h][1,6]naphthyridines." In The 21st International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2017. http://dx.doi.org/10.3390/ecsoc-21-04852.

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Kohyama, Izumi, Chikara Dohno, Changfeng Hong, and Kazuhiko Nakatani. "Development of tetrameric naphthyridine derivatives for DNA and RNA containing a G-G mismatch." In XVth Symposium on Chemistry of Nucleic Acid Components. Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 2011. http://dx.doi.org/10.1135/css201112367.

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Asanin, Darko, Tina Andrejević, Sanja Skaro-Bogojevic, et al. "Antimicrobial activity and DNA/BSA binding study of new silver(I) complexes with 1,8-naphthyridine." In 6th International Electronic Conference on Medicinal Chemistry. MDPI, 2020. http://dx.doi.org/10.3390/ecmc2020-07372.

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Angibaud, Patrick R., Michel Obringer, Julien Marin, et al. "Abstract 3641: Identification of naphthyridines as potent inhibitors of fibroblast growth factor receptor kinase family." In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-3641.

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Andrighetto, Rosália, Helio G. Bonacorso, Jussara Navarini, Nícolas Krüger, Marcos A. P. Martins, and Nilo Zanatta. "General Pathway for One-Pot Synthesis of Trifluoromethyl- Containing 2-Amino-cycloalka[b][1,8]naphthyridines." In 14th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-14bmos-r0008-2.

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Fallon, Kealan, Nilushi Wijeyasinghe, Eric Manley, Tobin Marks, Thomas D. Anthopoulos, and Hugo A. Bronstein. "Indolo-naphthyridine-6,13-dione thiophene building block for conjugated polymer electronics: Molecular origin of ultrahigh n-type mobility (Conference Presentation)." In Organic Field-Effect Transistors XVI, edited by Oana D. Jurchescu and Iain McCulloch. SPIE, 2017. http://dx.doi.org/10.1117/12.2273880.

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Mistri, Tapan Kumar, and S. Porwal. "How effective is direct targeting of genes instead of gene products in providing promising lead: Lessons from discovery of naphthyridine-azaquinilone as lead for Huntington ’s disease." In 14TH INTERNATIONAL CONFERENCE ON MATERIALS PROCESSING AND CHARACTERIZATION 2023. AIP Publishing, 2024. http://dx.doi.org/10.1063/5.0193240.

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