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Dissertations / Theses on the topic 'Neurosurgeon'

Author: Grafiati
Published: 4 June 2021
Last updated: 14 February 2022

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1

Nicholson, Marilyn Redmon. "The struggle for educational attainment a case study of the first African American female neurosurgeon /." [Pensacola, Fla.] : University of West Florida, 2005. http://purl.fcla.edu/fcla/etd/WFE0000053.

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2

Ögren, Kenneth. "Psychosurgery in Sweden 1944 - 1958 : the practice, the professional and media discourse." Doctoral thesis, Umeå universitet, Psykiatri, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1084.

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Background. The pioneering early experiments of prefrontal lobotomy were performed in 1944 by neurosurgeons in Stockholm in collaboration with psychiatrists. There was a rapid implementation of the new surgical approach. In 1946 and 1947 the two state mental hospitals, Umedalen and Sidsjön, introduced prefrontal lobotomy on a large scale. General surgeons now performed operations, a practice which was established all over Sweden. Prefrontal lobotomy was burdened, in certain city hospitals, by an initially high rate of postoperative mortality reaching more than 15 %. Pre-frontal lobotomy was ph
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3

Bergqvist, Saga. "Raman spectroscopy in neurosurgery." Thesis, Luleå tekniska universitet, Institutionen för teknikvetenskap och matematik, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:ltu:diva-78665.

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Brain tumors or brain cancer is a disease than affects people of all ages. The median age of a person living with a brain tumor is 60 years, it is however a disease that affects children and young adults in high grade. Brain cancer is the second most common type of cancer among children and is also the most common cause of cancer related death among this group. To ensure that the damages on the brain is as small as possible, it is important that a tumor can be diagnosed and removed as early as possible. Previous methods of diagnosis is based on biopsy where a part of the tumor is removed and e
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4

Hirabayashi, Hidehiro. "Stereotactic imaging in functional neurosurgery." Doctoral thesis, Umeå universitet, Klinisk neurovetenskap, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-55141.

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Background: The birth of stereotactic functional neurosurgery in 1947 was to a great extent dependent on the development of ventriculography. The last decades have witnessed a renaissance of functional stereotactic neurosurgery in the treatment of patients with movement disorders. Initially, these procedures were largely based on the same imaging technique that had been used since the birth of this technique, and that is still used in some centers. The introduction of new imaging modalities such as Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) provided new potentials, but also
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5

Diepenbrock, Stefan, Jörg-Stefan Praßni, Florian Lindemann, Hans-Werner Bothe, and Timo Ropinski. "Interactive Visualization Techniques for Neurosurgery Planning." University of Münster, Germany, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-92863.

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We present concepts for pre-operative planning of brain tumor resections. The proposed system uses a combination of traditional and novel visualization techniques rendered in real-time on modern GPUs in order to support neurosurgeons during intervention planning. A set of multimodal 2D and 3D renderings conveys the relation between the lesion and the various structures at risk and also depicts data uncertainty. To facilitate efficient interactions while providing a comprehensible visualization, all employed views are linked. Furthermore, the system allows the surgeon to interactively define th
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6

Kochan, Martin. "Enhancing registration for image-guided neurosurgery." Thesis, University College London (University of London), 2018. http://discovery.ucl.ac.uk/10045247/.

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Pharmacologically refractive temporal lobe epilepsy and malignant glioma brain tumours are examples of pathologies that are clinically managed through neurosurgical intervention. The aims of neurosurgery are, where possible, to perform a resection of the surgical target while minimising morbidity to critical structures in the vicinity of the resected brain area. Image-guidance technology aims to assist this task by displaying a model of brain anatomy to the surgical team, which may include an overlay of surgical planning information derived from preoperative scanning such as the segmented rese
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7

Munger, Patrice. "Accuracy considerations in MR image-guided neurosurgery." Thesis, McGill University, 1994. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=22780.

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This thesis studies various aspects of the accuracy issue in image-guided neurosurgery (IGNS). Factors such as registration, MR geometrical distortions and accuracy of digitizing device, are theoretically described in a general model of IGNS.<br>The means of registering the patient to its image data is then studied, starting with the definition of registration error. Computer simulations of registration by homologous point matching are described along with a clinical study comparing homologous point matching and surface matching registration methods.<br>A 3-D MR geometrical distortion experime
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8

Greger, Klaus. "OligoChannel spectral analysis in stereotactic laser neurosurgery." [S.l.] : [s.n.], 2003. http://deposit.ddb.de/cgi-bin/dokserv?idn=967776384.

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9

Clonda, Diego. "Automatic thalamic labeling for image-guided neurosurgery." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape11/PQDD_0007/MQ44150.pdf.

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10

Livingstone, Alison A. "Neuropsychological outcome following neurosurgery for mental disorder." Thesis, University of Edinburgh, 2003. http://hdl.handle.net/1842/28446.

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Neurosurgery for mental disorder (NMD) continues to exist as one of a range of treatments available to individuals who experience severe and intractable psychiatric illness. Historically, this particular use of ablative neurosurgery has attracted a considerable amount of interest and controversy. Despite modern advances in both technical procedure and understanding of the disorders for which NMD is indicated, the irreversibility of these procedures continues to attract attention from both public and professional groups alike. To date, indisputable evidence regarding the efficacy and frequency
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11

Vathalloor, Mathew Manoj. "Neuron guidance and nano-neurosurgery using optical tools." Doctoral thesis, Universitat Politècnica de Catalunya, 2009. http://hdl.handle.net/10803/33075.

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12

Majithia, Vishal. "Intersubject surface mapping with nonrigid registration for neurosurgery." [Gainesville, Fla.] : University of Florida, 2005. http://purl.fcla.edu/fcla/etd/UFE0013325.

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13

Aswapathi, Ramesh Ganesh Gautham. "Set Screw Break-Off Study In Spinal Neurosurgery." Available to subscribers only, 2009. http://proquest.umi.com/pqdweb?did=1885431371&sid=7&Fmt=2&clientId=1509&RQT=309&VName=PQD.

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14

Akram, Harith. "Application of MRI connectivity in stereotactic functional neurosurgery." Thesis, University College London (University of London), 2018. http://discovery.ucl.ac.uk/10052005/.

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This thesis examines potential applications of advanced MRI-connectivity studies in stereotactic functional neurosurgery. Several new analysis methodologies are employed to: (1) build predictive models of DBS surgery outcome; (2) refine the surgical target and (3) help build a better understanding of the pathogenesis of the treated conditions and the mechanism of action of DBS therapy. The experimental component is divided into three main parts focusing on the following pathologies: (1) Parkinson’s disease (PD), (2) tremor and (3) trigeminal autonomic cephalalgias (TAC). Section I: In the firs
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15

Depaoli, Damon, and Damon Depaoli. "Guiding deep brain stimulation neurosurgery with optical spectroscopy." Doctoral thesis, Université Laval, 2019. http://hdl.handle.net/20.500.11794/37637.

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Savoir différiencier les différentes types de tissus représente un aspect important lors d’interventions médicales, que ce soit pour aider au diagnostic d’une maladie ou pour le guidage chirurgical. Il est généralement très difficile de distinguer les tissus sains des tissus pathologiques à l’oeil nu et la navigation chirurgicale peut parfois être difficile dans les grands organes où la structure ciblé se trouve enfouie profondément. De nouvelles méthodes susceptibles d’accroître la réussite de telles interventions médicales suscitent actuellement de l’intérêt chez les professionnels de la san
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16

Daga, P. "Towards efficient neurosurgery : image analysis for interventional MRI." Thesis, University College London (University of London), 2014. http://discovery.ucl.ac.uk/1449559/.

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Interventional magnetic resonance imaging (iMRI) is being increasingly used for performing imageguided neurosurgical procedures. Intermittent imaging through iMRI can help a neurosurgeon visualise the target and eloquent brain areas during neurosurgery and lead to better patient outcome. MRI plays an important role in planning and performing neurosurgical procedures because it can provide highresolution anatomical images that can be used to discriminate between healthy and diseased tissue, as well as identify location and extent of functional areas. This is of significant clinical utility as i
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17

Yoshida, Jun. "Molecular Neurosurgery Using Gene Therapy to Treat Malignant Glinoma." 名古屋大学医学部, 1996. http://hdl.handle.net/2237/6179.

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18

Eriksson, Ola. "Characterisation and modelling of radiofrequency lesioning in functional neurosurgery /." Linköping : Univ, 2001. http://www.bibl.liu.se/liupubl/disp/disp2001/tek693s.pdf.

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19

Whittle, Ian Roger. "Clinical applications of somatosensory evoked potentials in pediatric neurosurgery /." Title page, contents and summary only, 1985. http://web4.library.adelaide.edu.au/theses/09MD/09mdw627.pdf.

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20

Uff, Christopher. "The evaluation of advanced ultrasound elastographic techniques in neurosurgery." Thesis, Institute of Cancer Research (University Of London), 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.543946.

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21

Gerard, Ian. "An analysis of tracking error in image guided neurosurgery." Thesis, McGill University, 2014. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=121328.

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Each year, thousands of Canadians undergo neurosurgery to areas of the brain that are critical to movement, vision, sensation, or language. Recent literature demonstrates a significantly increased survival benefit with complete resection of primary and secondary brain tumours. Image guided neurosurgery uses technology that tracks a patient and special tools simultaneously to use preoperative images in order to help guide a surgeon through the surgery. There are many different types of errors that can arise during these types of interventions related to technical, physical and biological factor
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22

Morgan, Paul Simon. "Spatial distortion in MRI with application to stereotactic neurosurgery." Thesis, University of Nottingham, 1999. http://eprints.nottingham.ac.uk/13091/.

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The aim of this work was to implement a thorough method for quantifying the errors introduced to frame-based neurosurgical stereotactic procedures by the use of MRI. Chang & Fitzpatrick's reversed gradient distortion correction method was used, in combination with a phantom, to measure these errors. Spatial distortion in MR images of between 1 mm and 2 mm was measured. Further analysis showed that this typically introduced an additional error in the coordinate of the actual treatment point of 0.7 mm. The implications of this are discussed. The main source of distortion in the MR images used fo
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23

Mjoli, Ntethelelo. "Brain arteriovenous malformations presenting with haemorrhage." Master's thesis, University of Cape Town, 2012. http://hdl.handle.net/11427/2886.

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24

Semple, Patrick Lyle. "Pituitary apoplexy : can histopathology, radiological imaging and predisposing factors be used in predicting outcome?" Doctoral thesis, University of Cape Town, 2008. http://hdl.handle.net/11427/2890.

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Includes abstract.<br>Includes bibliographical references (leaves 98-112).<br>Pituitary apoplexy is an uncommon, yet potentially fatal illness, usually the result of infarction, hemorrhage or a combination of both in a pituitary tumor. The management of pituitary apoplexy consists of replacement therapy and in the majority of patients, surgical decompression, although some cases may be treated conservatively. Up to now no study has attempted to separate the two histopathological types of pituitary apoplexy or to analyze their clinical and radiological significance on presentation and outcome.
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25

Figaji, Anthony A. "Multimodality monitoring in paediatric severe traumatic brain injury : the contributions of brain oxygen, transcranial doppler and autoregulation monitoring to conventional methods on monitoring." Doctoral thesis, University of Cape Town, 2008. http://hdl.handle.net/11427/2882.

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Includes abstract.<br>Includes bibliographical references (p. 175-218).<br>Traumatic brain injury (TBI) is a highly complex clinical condition in the most complex organ of the body. The foundation of care of the patient with severe TBI is the prevention of secondary insults to the brain. This relies on conventional monitoring tools to identify patients at risk, but often these may fail to detect important secondary insults. Moreover, the therapies that are used commonly in the critical care environment all have potential adverse effects, many of which may not be evident. TBI treatment in child
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26

Leng, Jeanette Anne. "Neuropsychological sequelae of paediatric posterior fossa brain tumours : the effect on quality of life." Doctoral thesis, University of Cape Town, 2002. http://hdl.handle.net/11427/2885.

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27

Padayachy, Llewellyn. "Ultrasound as a non-invasive diagnostic tool in paediatric neurosurgery : relationship between the optic nerve sheath diameter (ONSD) and intracranial pressure (ICP)." Doctoral thesis, University of Cape Town, 2015. http://hdl.handle.net/11427/16787.

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Includes bibliographical references<br>Background: Assessment of intracranial pressure (ICP) is an essential aspect in the management of most neurosurgical conditions in children. While invasive ICP monitoring is considered the criterion standard, the need for a reliable, non-invasive, easy-to-use and accurate method to detect and monitor raised ICP has inspired the development of many useful techniques. The present study examined the relationship between transorbital ultrasound measurement of the optic nerve sheath diameter (ONSD) and invasively measured ICP in children, as well as the influe
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28

Nair, Omesan. "Profiling medulloblastoma and juvenile pilocytic astrocytoma brain tumours in a South African paediatric cohort." Doctoral thesis, University of Cape Town, 2017. http://hdl.handle.net/11427/26896.

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Brain tumours in children are one of the most challenging diseases to treat, and so outcomes are variable and often lacking. There are currently no reliable data of presentation of disease, the spectrum of tumours treated, how these are treated, and what the outcomes are for children in South Africa, and certainly no molecular biology data. In this respect, this thesis investigated the two commonest types of childhood brain tumour, the highly malignant Medulloblastoma (MB) and the generally less aggressive Juvenile Pilocytic Astrocytoma (JPA) with relation to their molecular biology and their
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29

Fieggen, Anthony Graham. "The Cape Town Stereotactic pointer clinical development and Applications." Doctoral thesis, University of Cape Town, 2009. http://hdl.handle.net/11427/2881.

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This dissertation describes the development and clinical use of a novel stereotactic neurosurgical system, the Cape Town Stereotactic Pointer (CTSP). This system has four main components; a halo containing three fiducials also serves as the platform for a tripod pointing device which is set with the aid of a 3D phantom or a printed setting diagram, and software which enables transformation of imaging space into patient space. Laboratory tests indicated an application accuracy of 1.9 +/- 0.6mm using the 3D phantom to set the tripod. From the first clinical application, the system underwent a se
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30

Pillay, Robin. "Adult neoplastic spinal cord compression." Master's thesis, University of Cape Town, 2000. http://hdl.handle.net/11427/2888.

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Bibliography : leaves 91-107.<br>Spinal cord compression ( SCC ) constitutes a neurological emergency, and if left untreated, can result in permanent irreversible neurological dysfunction. Disabilities can range from mild weakness to complete quadriplegia with the inherent associated mental, physical and emotional suffering .The burden of cost to the individual and community is enormous.
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31

Padayachy, L. C. "The prevalence of cerebral hypoxia/ischemia in pediatric severe traumatic brain injury." Master's thesis, University of Cape Town, 2010. http://hdl.handle.net/11427/2887.

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32

Thompson, Crispin. "Hyperextension injury of the cervical spine with central cord syndrome." Master's thesis, University of Cape Town, 2013. http://hdl.handle.net/11427/2892.

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33

Enslin, Johannes Marthinus Nicolaas. "Outcomes of decompressive craniectomy in adults with severe traumatic brain injury: the Groote Schuur Hospital experience." Master's thesis, University of Cape Town, 2014. http://hdl.handle.net/11427/13110.

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Includes bibliographical references.<br>Object: The aim of this study was to assess outcome following decompressive craniectomy in adults with severe traumatic brain injury (TBI) in a South African neurosurgical unit. Methods: During a 78 month period (January 2005 – June 2011), 76 patients that underwent decompressive craniectomy for TBI in an attempt to lower raised intracranial pressure (ICP) were reviewed . All were older than 14 years and mass lesions were included. Thirty nine point four percent of the patients sustained blunt, low velocity injuries to the head and 19% were invol
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34

Mankahla, Ncedile. "The Changing Face of Craniopharyngioma Treatment in Young Children and its Challenges at a Single Centre in a Developing World Context." Master's thesis, Faculty of Health Sciences, 2019. http://hdl.handle.net/11427/31106.

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Objective: To retrospectively review our institutional experience with the treatment of paediatric craniopharygiomas and assess the evolution in management and influence on patient outcomes. Patients and Methods: A retrospective review from January 1995 to December 2015 of children age <14 treated at a single institution. Data collected included admission clinical features, endocrine function, surgery performed, surgical outcome, intracystic therapy and radiotherapy. Long-term functional outcome was calculated considering hormonal dependence, level of independence and schooling. Resul
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35

Ben, Husien Mohammed. "Symptomatic developmental venous anomalies." Master's thesis, University of Cape Town, 2016. http://hdl.handle.net/11427/20556.

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Developmental Venous Anomalies are a normal variant that may be associated with other cerebral vascular malformation. They have bean previously referred to Venous angiomas. DVAs are the most frequently encountered cerebral vascular malformation and their incidence is reported to be high as2.6%. DVAs are classified into two types based on draining veins. Either deep or superficial. Those that drain into sub-ependymal veins are classified as deep and those that drain into cortical pial veins are classified as superficial. The trans-cerebral veins join either the deep or superficial venous system
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36

Figaji, Anthony Aaron. "Decompressive craniectomy in children with traumatic brain injury." Master's thesis, University of Cape Town, 2005. http://hdl.handle.net/11427/2883.

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Includes bibliographical references (leaves 58-72).<br>Although the conventional role of the operation was that of a salvage procedure when medical therapy failed in the treatment of raised intracranial pressure (ICP), two important concepts have emerged in the recent literature that appear to challenge that approach. In addition to the lack of evidence supporting benefit from current forms of treament, evidence from diverse studies that use data from magnetic resonance images, cerebral owygenation and cerebral blood flow measurements have highlighted potential adverse effects that may occur w
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37

Wegoye, Emmanuel. "Radiotherapy for head and neck paragangliomas: A 10 year retrospective review 2005-2014 at Groote Schuur Hospital and UCT Private academic hospital." Master's thesis, Faculty of Health Sciences, 2019. http://hdl.handle.net/11427/30840.

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Objective. Over the last two decades there has been increasing evidence that radiosurgery and radiotherapy management of skull-base paragangliomas is as effective as microsurgical resection and carries less morbidity. This 10 year retrospective review of 24 patients in a single institution, treated over 10 years assesses tumour control rates and morbidity associated with radiosurgery and radiotherapy treatment. Method. Patients with a radiological diagnosis of skull-base paragangliomas were treated with different techniques of stereotactic and image-guided radiotherapy delivering hypo fraction
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38

Taylor, Allan Grant. "Advantages of delayed ventriculoperitoneal shunting in post haemorrhagic hydrocephalus seen in low birth weight infants." Master's thesis, University of Cape Town, 1999. http://hdl.handle.net/11427/26759.

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INTRODUCTION: The incidence of intraventricular hemorrhage (IVH) in very low birth weight infants is between 25 and 50%. Approximately 13-60% of these patients will develop progressive post hemorrhagic hydrocephalus (PHH) and of these 22- 70% will require CSF diversion. The most common therapeutic intervention is insertion of a ventriculoperitoneal shunt but there is considerable controversy surrounding the timing of the operation. Most authors promote early surgery to prevent secondary injury from hydrocephalus but it was our impression that this was associated with a higher incidence of shun
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39

Roytowski, David. "Intracranial pressure monitoring as an early predictor of third ventriculostomy outcome." Master's thesis, University of Cape Town, 2012. http://hdl.handle.net/11427/5935.

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40

Semple, Patrick Lyle. "Severe head injuries in children." Master's thesis, University of Cape Town, 1997. http://hdl.handle.net/11427/26252.

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The aim of this dissertation is to review the current literature on severe head injuries in children, with particular respect to epidemiology, clinical features and investigation, pathophysiology, management and outcome. In addition a retrospective study was carried out on severe head injuries at Red Cross War Memorial Children's Hospital. Finally, the findings of this study are discussed in the light of the experience of other neurosurgical and trauma centres. In this way similarities as well as features peculiar to our setting can be identified with the aim of improving the understanding and
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41

Ssenyonga, Peter Kato. "The endovascular treatment of traumatic cranio-cervical vascular injuries." Master's thesis, University of Cape Town, 2013. http://hdl.handle.net/11427/2891.

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42

Collins, Donald Louis. "Volumetric rendering of medical data : applications to stereotactic neurosurgery planning." Thesis, McGill University, 1989. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=59545.

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This thesis addresses the problem of registration, merging and viewing medical images from multiple modalities for stereotactic surgery planning. A technique is presented, using volumetric rendering of tomographic data, to create anatomical perspective projections that can be easily merged with vascular projections.<br>The geometry of the digital subtraction angiogram (DSA) projection is reproduced by the rendering process to enable registration between the DSA radiograph and the volumetric projection. The viewing parameters are calculated from the location of fiducial markers in the image. Ea
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43

Henri, Christopher J. "Application of stereoscopic digital subtraction angiography to stereotactic neurosurgery planning." Thesis, McGill University, 1989. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=55692.

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44

Ovinis, Mark. "Computer vision techniques for a robot-assisted emergency neurosurgery system." Thesis, Loughborough University, 2011. https://dspace.lboro.ac.uk/2134/8502.

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This thesis presents the development of computer vision techniques for a robot-assisted emergency neurosurgery system that is being developed by the Mechatronics in Medicine group at Loughborough University, UK, and situates them within the context of the overall project. There are two main contributions in this thesis. The first is the development of a registration framework, to establish spatial correspondence between a preoperative plan of a patient (based on computed tomography images) and the patient. The registration is based on the rigid transformation of homologous anatomical soft tiss
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45

Fedorov, andriy Yuri. "Enabling technology for non-rigid registration during image-guided neurosurgery." W&M ScholarWorks, 2009. https://scholarworks.wm.edu/etd/1539623540.

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In the context of image processing, non-rigid registration is an operation that attempts to align two or more images using spatially varying transformations. Non-rigid registration finds application in medical image processing to account for the deformations in the soft tissues of the imaged organs. During image-guided neurosurgery, non-rigid registration has the potential to assist in locating critical brain structures and improve identification of the tumor boundary. Robust non-rigid registration methods combine estimation of tissue displacement based on image intensities with the spatial re
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46

Mühle, Richard, Hannes Ernst, Stephan B. Sobottka, and Ute Morgenstern. "Workflow and hardware for intraoperative hyperspectral data acquisition in neurosurgery." Walter de Gruyter GmbH, 2020. https://tud.qucosa.de/id/qucosa%3A74394.

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To prevent further brain tumour growth, malignant tissue should be removed as completely as possible in neurosurgical operations. Therefore, differentiation between tumour and brain tissue as well as detecting functional areas is very important. Hyperspectral imaging (HSI) can be used to get spatial information about brain tissue types and characteristics in a quasi-continuous reflection spectrum. In this paper, workflow and some aspects of an adapted hardware system for intraoperative hyperspectral data acquisition in neurosurgery are discussed. By comparing an intraoperative with a laborator
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47

Hyam, Jonathan A. "Deep brain stimulation : manipulation of physiology and pathophysiology by neurosurgery." Thesis, University of Oxford, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.589612.

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The capability of the brain to control the body has been recognised for millennia. This thesis evaluates the ability of neurosurgery, in the form of DBS, to manipulate the motor system, in which it is already established as a therapy, and the cardiovascular and respiratory systems, in which its application as a therapy would represent a major paradigm shift in medical practice. Patients with in-dwelling deep brain stimulators were enrolled in a series of experiments. Methodological techniques included the recording and analysis of cardiovascular and lung function indices, deep brain local fiel
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48

Owaki, Hisayuki. "Non-adhesive cyanoacrylate as an embolic material for endovascular neurosurgery." Kyoto University, 2000. http://hdl.handle.net/2433/180862.

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49

Van, Geems Barbara Anne. "The development of a simple stereotactic device for neurosurgical applications." Thesis, University of Cape Town, 1997. http://hdl.handle.net/11427/26285.

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50

Mogere, Edwin. "Impact of secondary insults on the outcome of paediatric traumatic brain injury : a retrospective cross sectional study at the Red Cross Children’s Hospital, Cape Town." Master's thesis, University of Cape Town, 2013. http://hdl.handle.net/11427/13970.

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Includes bibliographical references.<br>Secondary insults in severe traumatic brain injury (TBI) may worsen outcome; however, these are poorly characterized in children. For example, despite the known association between intracranial pressure (ICP) and poor outcome, there are few large paediatric series on the subject, definitions vary, functional outcome is often not assessed, and the best measures to assess ICP for statistical analysis are unknown. We aimed to document the frequency of secondary insults, and the association of various ICP measures, with outcome in a large cohort of paediatri
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