Relevant bibliographies by topics / Paracetamol

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Paracetamol'

Author: Grafiati
Published: 4 June 2021
Last updated: 25 July 2025

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Journal articles on the topic "Paracetamol"

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Hinz, Burkhard, and Kay Brune. "Paracetamol and cyclooxygenase inhibition: is there a cause for concern?" Annals of the Rheumatic Diseases 71, no. 1 (2011): 20–25. http://dx.doi.org/10.1136/ard.2011.200087.

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Paracetamol is recommended as first-line therapy for pain associated with osteoarthrosis and is one of the most widely used over-the-counter analgesic drugs worldwide. Despite its extensive use, its mode of action is still unclear. Although it is commonly stated that paracetamol acts centrally, recent data imply an inhibitory effect on the activity of peripheral prostaglandin-synthesising cyclooxygenase enzymes. In this context paracetamol has been suggested to inhibit both isoforms in tissues with low levels of peroxide by reducing the higher oxidation state of cyclooxygenase enzymes. Two rec
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Bante, Punam, Shikha Sethiya, Mangala Thakare, and Dr.Varsha Dhurvey. "The Imapact of Paracetamol on the Excretory System: A Review of Toxicity and Protective Strategies." International Journal of Scientific Research in Biological Sciences 12, no. 2 (2025): 32–40. https://doi.org/10.26438/ijsrbs.v12i2.674.

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Paracetamol, a painkiller and antipyretic, works well for pain and fever. But its availability and perceived safety puts us at risk of accidental overdose which can cause liver damage, kidney failure, and other side effects. Paracetamol works by inhibiting COX-2 enzymes, reducing prostaglandin production, and targeting the hypothalamus to relieve pain, inflammation, and fever. But overdose can cause severe kidney damage and impairment leading to acute and chronic renal dysfunction. Studies have shown that paracetamol administration can cause nephrotoxicity characterized by histopathological ch
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Kocot-Kępska, Magdalena. "Połączenie paracetamolu i tramadolu – fakty i mity." Medycyna Faktów 17, no. 4(65) (2024): 516–22. https://doi.org/10.24292/01.mf.0424.13.

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Skojarzenie paracetamolu z tramadolem – analgetyków o odmiennych mechanizmach działania, oddziałujących na różne szlaki nocycepcji – zapewnia skuteczne leczenie różnych rodzajów bólu i pozwala na zmniejszenie dawek poszczególnych leków dla osiągnięcia tego samego efektu przeciwbólowego jak przy monoterapii. Paracetamol jest skuteczny w bólu receptorowym, tramadol zaś w bólu o charakterze receptorowym, neuropatycznym i nocyplastycznym. Profile działania obu leków uzupełniają się, dając efekt synergizmu hiperaddycyjnego. Dodatkowo połączenie może być jeszcze kojarzone z innymi analgetykami i koa
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Begum, Shaheen, Poojitha Harisree G, and Rashida Anjum M S. "A Short Review on Biological Activities of Paracetamol Derivatives." International Journal of Pharmaceutical Sciences and Nanotechnology(IJPSN) 16, no. 1 (2023): 6309–25. http://dx.doi.org/10.37285/ijpsn.2023.16.1.5.

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Paracetamol reduces body temperature with multiple mechanisms. Paracetamol is chemically 4-hydroxy acetanilide and has a good safety profile. Following its successful use as an over-the-counter antipyretic and analgesic medication, several attempts were made to increase the potency, mask the bitter taste, and decrease the toxicity of this drug by modifications at the phenyl ring, acetamido group, and hydroxyl group. The free hydroxyl group of paracetamols was masked to obtain prodrugs (carbonate prodrugs, ester prodrugs like alanine-prodrug, proline-prodrug, galactosylated prodrug, and mutual
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Coman, Laurențiu, Horia Păunescu, Cristina Isabel Viorica Ghiță, et al. "Paracetamol-Induced Hypothermia in Rodents: A Review on Pharmacodynamics." Processes 10, no. 4 (2022): 687. http://dx.doi.org/10.3390/pr10040687.

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Paracetamol can induce hypothermia in humans and rodents. The study’s aim is to review the mechanisms of paracetamol-induced hypothermia in rodents or the results issued from in vitro studies on the same species’ tissues (in doses that do not produce hepatic impairment) using the latest developments published in scientific journals over the last 15 years. Available human studies are also analysed. An extensive search in PubMed databases exploring the hypothermic response to paracetamol was conducted. 4669 articles about paracetamol’s effects on body temperature in mice or rats were found. Afte
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Hamed Almurisi, Samah, Khater AL-Japairai, Farhan Alshammari, Fawaz Alheibshy, Rana M. F. Sammour, and Abd Almonem Doolaanea. "Stability of Paracetamol Instant Jelly for Reconstitution: Impact of Packaging, Temperature and Humidity." Gels 8, no. 3 (2022): 144. http://dx.doi.org/10.3390/gels8030144.

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The stability of the medicinal product is a major concern in the pharmaceutical industry and health authorities, whose goal is to guarantee that drugs are delivered to patients without loss of therapeutic properties. This study aims to evaluate the effect of environmental conditions and packaging on the stability of paracetamol instant jelly sachets based on both chemical and physical stability. The paracetamol instant jelly was packaged in plastic sachets (packaging 1) and sealed aluminium bags in screw-capped amber glass bottles (packaging 2), which were stored in real-time and accelerated s
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Mohamed, Ashma, Alexa Wacker, and Martin Schmidt. "Chronic Misuse of Paracetamol in OCD Without Hepatic Injury: A Case Report and Literature Review." BJPsych Open 8, S1 (2022): S123. http://dx.doi.org/10.1192/bjo.2022.364.

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AimsParacetamol is a commonly used antipyretic and analgesic over the counter medication. In acute or chronic overuse it is associated with dose-dependent hepatic injury. There is a narrow therapeutic margin and that consistent use of as little as 7.5 g/day may be hazardous. Unintentional overdose with paracetamol is the most common cause of acute liver failure in the United Kingdom Here we present an unusual case of a 60-year-old lady with a reported chronic history of self-medicating with an above daily recommended dose of paracetamol without evidence of hepatic injury.MethodsA 60-year-old C
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Ahmed Mejbel, Elham, Saif Subhi Noori, Adeeb Shakir Mahmood, Hussein Riyadh Abdul Kareem Al-Hetty, and Mohammed H. Musleh. "Oleuropein Protects against the Development of Kidneys Induced by Paracetamol in Albino Male Rats." HAYATI Journal of Biosciences 32, no. 1 (2024): 254–62. http://dx.doi.org/10.4308/hjb.32.1.254-262.

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Paracetamol treatment is considered one of the treatments used to relieve pain and antipyretic. Therefore, excessive doses and long-term use lead to organ toxicity. Paracetamol treatment is considered one of the treatments used to relieve pain and antipyretic. Therefore, excessive doses and long-term use lead to organ toxicity. The aim of the study was to investigate the protective effect of Oleuropein extracted from olive leaves on the physiological and histological aspects induced by Paracetamol in a rat model. The methods used 25 albino Swiss rats randomly distributed into five groups with
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LORELL, Juan, Kathy IVANA, Joselyn P. W. TANOTO, et al. "In silico testing of C9H12ClNO2 and C6H5Cl2NO as derivatives of acetaminophen using molecular docking method." Notulae Scientia Biologicae 16, no. 1 (2024): 11632. http://dx.doi.org/10.55779/nsb16111632.

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Paracetamol, a commonly used analgesic and antipyretic medication, is well-known for its ability to relieve pain and reduce temperature. However, there is a constant push to improve its therapeutic efficacy, especially towards increasing its oral bioavailability. The increase in bioavailability will lead to a better reception of the drugs by the body. This research aims to provide valuable insights into the molecular mechanisms underlying paracetamol’s mode of action and propose novel strategies for enhancing its therapeutic effectiveness. We investigated the notion of functional group alterat
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Atharv, Gangarde* Kiran Bibave. "Study Of Adverse Drug Reaction Of Paracetamol Dose." International Journal of Pharmaceutical Sciences 2, no. 6 (2024): 467–79. https://doi.org/10.5281/zenodo.11521608.

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Acetaminophen, generally known as paracetamol, is one of the most commonly used over-the-counter analgesics and antipyretics globally. It is frequently administered for the relief of pain and fever in both adults and children. However, calculating the proper dosage of paracetamol can be difficult due to a variety of factors such as age, weight, underlying medical conditions, and concurrent drugs. This presentation seeks to offer a comprehensive evaluation of the optimal paracetamol dosage using the most recent research and guidelines available till September 2021. The review investigates parac
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Dissertations / Theses on the topic "Paracetamol"

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Mohd, Zaki Hamizah. "Spectroscopy surface analysis of paracetamol and paracetamol and excipient systems." Thesis, University of Manchester, 2011. https://www.research.manchester.ac.uk/portal/en/theses/spectroscopy-surface-analysis-of-paracetamol-and-paracetamol-and-excipient-systems(2f50af69-fb35-487b-8065-46aa3c86f96c).html.

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A detailed, fundamental understanding of the surface properties of molecular crystals and their interaction with adsorbing molecules (e.g. excipients) is important for tailoring the stability of formulations and the bioavailability of Active Pharmaceutical Ingredient (APIs). Few fundamental experimental studies with surface sensitive probes have been carried out for organic molecular crystals. X-ray photoelectron spectroscopy (XPS) is an established surface analysis method in the fields of adsorption, catalysis and surface chemistry of inorganic crystals. It has high surface sensitivity, probi
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Castro, Pedro Luís Pereira de. "Farmacocinética do paracetamol." Master's thesis, [s.n.], 2014. http://hdl.handle.net/10284/4415.

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Projeto de Pós-Graduação/Dissertação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Ciências Farmacêuticas<br>O paracetamol é um dos analgésicos e antipiréticos mais utilizados em crianças e adultos por possuir uma janela terapêutica larga com poucos efeitos adversos. No entanto, por ser um medicamento não sujeito a receita médica, é por vezes utilizado em sobredosagem, podendo provocar hepatotoxicidade decorrente do esgotamento dos níveis de glutationa hepática e do excesso de produção de N-acetil-p-benzoquinonaimina (NAPQI), um metabol
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Robinson, D. "Factors influencing paracetamol overdose." Thesis, Queen's University Belfast, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.403484.

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Flodell, Amanda. "Risker vid användning av paracetamol under graviditet : Risker vid användning av paracetamol under graviditet." Thesis, Umeå universitet, Kemiska institutionen, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-102007.

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Cabral, Flavia Helena Costa. "Alterações morfologicas testiculares provocadas pelo cadmio, paracetamol e cadmio associado ao paracetamol, em ratos." [s.n.], 1996. http://repositorio.unicamp.br/jspui/handle/REPOSIP/317850.

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Orientador: Mary Anne Heidi Dolder<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Biologia<br>Made available in DSpace on 2018-07-21T09:40:36Z (GMT). No. of bitstreams: 1 Cabral_FlaviaHelenaCosta_M.pdf: 7932022 bytes, checksum: 5df8caed27891d2ed2c74e69d6748a6b (MD5) Previous issue date: 1996<br>Resumo: O cádmio é um elemento químico, reconhecido atualmente como perigoso devido sua alta toxicidade e os efeitos deletérios que provoca nos seres vivos. Recentemente também tem sido investigadas com maior interesse e atenção, algumas drogas vendidas sem prescrições méd
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Chiew, Angela. "Changing paradigms of paracetamol poisoning." Thesis, University of Sydney, 2020. https://hdl.handle.net/2123/23382.

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The overall objective of this thesis was to identify and examine areas for improvement in the management of paracetamol poisoning. Paracetamol is one of the commonest drugs taken in overdose in Australia and a common cause of acute liver injury in Western countries. Management of paracetamol poisoning includes assessment for the need of antidote (acetylcysteine) administration and decontamination in patients at risk of toxicity. Management in most follows standard guidelines and in those receiving early acetylcysteine are at very low risk of developing acute liver injury. However, circumstance
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Arakji, Jawad Ola. "Effekter av begränsad förpackningsstorlek för paracetamol." Thesis, Umeå universitet, Farmakologi, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-121837.

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SCIEUX, PIERRE. "Intoxication par le paracetamol chez l'adulte." Lille 2, 1989. http://www.theses.fr/1989LIL2M033.

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Bashir, Shazma. "Mechanism of Paracetamol (acetaminophen) induced hypothermia." Thesis, University of East London, 2018. http://roar.uel.ac.uk/7308/.

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Paracetamol is a potent analgesic and antipyretic with limited side effects compared to the nonsteroidal anti-inflammatory drugs (NSAIDs) and opiates. Worldwide paracetamol is commonly used to treat pain and fever in both children and adults. Although, this drug has been in clinical use for more than a century, the mechanisms of action are not fully understood. Historically some of the actions of paracetamol were attributed to the inhibition of central cyclooxygenase (COX-1 and COX-2) enzymes however given the weak inhibitory effects on COX-1 and COX-2 enzymes, alternative targets have been su
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Chevallier, Thierry. "Pharmacologie clinique du paracetamol en collyre." Nice, 1992. http://www.theses.fr/1992NICE6556.

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Books on the topic "Paracetamol"

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J, Meredith T., World Health Organization, Commission of the European Communities., and International Program on Chemical Safety., eds. Antidotes for poisoning by paracetamol. Published by Cambridge University Press on behalf of the World Health Organization and of the European Commission, 1995.

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N, Gregg, and Great Britain. Health and Safety Executive., eds. Paracetamol: Criteria document for an occupational exposure limit. HSE Books, 1994.

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Kiel, Universität, ed. Regionalanästhesie (Ilioinguinalblock) versus systemische Analgesie (Paracetamol): Vergleichende Untersuchung der Analgesiequalität nach kinderchirurgischen Eingriffen. [s.n.], 1998.

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Ricardo, Royder Yáñez, and Cruz Catata Teodora, eds. Mentisán, paracetamol o wira wira?: Jóvenes, salud e interculturalidad en los barrios mineros de Potosí. PIEB, Programa de Investigación Estratégica en Bolivia, 2006.

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National Register of Foreign Collaborations (India) and India. Dept. of Scientific & Industrial Research., eds. Technology in Indian paracetamol industry: A status report prepared under the National Register of Foreign Collaborations. Govt. of India, Dept. of Scientific & Industrial Research, Ministry of Science and Technology, 1994.

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Dan, Micon. Paracetamol. Independently Published, 2018.

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Joe, Smith. Paracetamol. Independently Published, 2018.

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executive, Health and safety. Paracetamol. Health and Safety Executive (HSE), 1994.

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Paracetamol. Royal Society of Chemistry, 2002.

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Goody, Bob. War & Paracetamol. Burning Eye Books, 2021.

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Book chapters on the topic "Paracetamol"

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McAllister-Williams, R. Hamish, Daniel Bertrand, Hans Rollema, et al. "Paracetamol." In Encyclopedia of Psychopharmacology. Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-540-68706-1_7004.

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Beyer, Karl-Heinz. "Paracetamol." In Biotransformation der Arzneimittel. Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-74386-3_242.

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Vidal, C., and W. R. Külpmann. "Paracetamol." In Lexikon der Medizinischen Laboratoriumsdiagnostik. Springer Berlin Heidelberg, 2018. http://dx.doi.org/10.1007/978-3-662-49054-9_2343-1.

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Vidal, C., and W. R. Külpmann. "Paracetamol." In Springer Reference Medizin. Springer Berlin Heidelberg, 2019. http://dx.doi.org/10.1007/978-3-662-48986-4_2343.

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Schneider, Achim, Günther Schlunck, and Viola Sieber. "Paracetamol." In Geburtshilfefibel. Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-97317-8_66.

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Bateman, D. Nicholas. "Acetaminophen (Paracetamol)." In Critical Care Toxicology. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-20790-2_108-1.

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Bateman, D. Nicholas. "Acetaminophen (Paracetamol)." In Critical Care Toxicology. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-20790-2_108-2.

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Wilson, John Fawcett. "Paracetamol (Acetaminophen)." In The Immunoassay Kit Directory. Springer Netherlands, 1995. http://dx.doi.org/10.1007/978-94-011-0679-5_38.

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Bateman, D. Nicholas. "Acetaminophen/Paracetamol." In Critical Care Toxicology. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-17900-1_108.

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Ginat, Daniel Thomas. "Acetominophen (Tylenol, Paracetamol)." In Neuroimaging Pharmacopoeia. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-12715-6_49.

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Conference papers on the topic "Paracetamol"

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VIVAR, Indra CASTRO, Catherine AZZARO-PANTEL, Alberto A. AGUILAR LASSERRE, and Fernando MORALES-MENDOZA. "Eco-Designing Pharmaceutical Supply Chains: A Process Engineering Approach to Life Cycle Inventory Generation." In The 35th European Symposium on Computer Aided Process Engineering. PSE Press, 2025. https://doi.org/10.69997/sct.185378.

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The environmental impacts of pharmaceutical production underscore the need for comprehensive life cycle assessments (LCAs). Offshoring manufacturing, a common cost-saving strategy in the pharmaceutical industry, increases supply chain complexity and reliance on countries like India and China for active pharmaceutical ingredients (APIs). The COVID-19 pandemic exposed Europe�s vulnerability to global crises, prompting initiatives such as the French government�s re-industrialization plan to relocate the production of fifty critical drugs. Paracetamol production has been prioritized, with recent s
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Lima, Fernando Arrais R. D., Amyr Crissaff Silva, Marcellus G. F. de Moraes, et al. "Development of a Hybrid Model for the Paracetamol Batch Dissolution in Ethanol Using Universal Differential Equations." In The 35th European Symposium on Computer Aided Process Engineering. PSE Press, 2025. https://doi.org/10.69997/sct.131534.

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Crystallization is a relevant process in the pharmaceutical industry for product purification and particle production. An efficient crystallization is characterized by crystals produced with the desired attributes. Therefore, modeling this process is a key point to achieve this goal. In this sense, the objective of this work is to propose a hybrid model to describe paracetamol dissolution in ethanol. The universal differential equations methodology is considered in the development of this model, using a neural network to predict the dissolution rate combined with the population balance equatio
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Santos, Nayara Julielen, ALEX TEODORO FERREIRA, and CRISTIANE MARIA FERNANDES DE MELO. "INTOXICAÇÃO POR PARACETAMOL EM FELINOS." In III Congresso Nacional de Especialidades Veterinárias On-line. Revista Multidisciplinar em Saúde, 2024. http://dx.doi.org/10.51161/convesp2024/33331.

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Malia, R. G., H. J. Kennedy, D. R. Triger, and F. E. Preston. "PROTECTIVE EFFECT OF VITAMIN K AGAINST ACETAMINOPHEN (PARACETAMOL) TOXICITY IN THE HAMSTER." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644341.

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We have previously reported that paracetamol may interfere with the metabolism of vitamin K via the vitamin K 2, 3-epoxide cycle. (Thrombosis and Haemostasis, 54,205,1985). In this study we have examined the effects of large doses of vitamin K on experimentally induced paracetamol hepatic necrosis in a hamster model. Paracetamol (1.2g/Kg) when given by gavage to 24 hamsters (Group I) resulted in 10 deaths (42%) at 24 hours. Simultaneous administration of lmg vitamin K intraperitoneally (Group II) reduced mortality to 3/24 (12%); mortality was 2/24 (8%) if vitamin K was given 4 hours after the
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Hidayati, Ika Ratna, Elys Oktaviana, Irma Nurtiana Syafitri, and Liza Pristianty. "Knowledge Levels and Paracetamol Self-Medication." In Health Science International Conference (HSIC 2017). Atlantis Press, 2017. http://dx.doi.org/10.2991/hsic-17.2017.42.

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Meng, Cui, Ruijuan Qu, Jinyan Liang, et al. "Photodegradation of Paracetamol in Nitrate Solution." In 2nd International Symposium on Aqua Science, Water Resource and Low Carbon Energy. AIP, 2010. http://dx.doi.org/10.1063/1.3529338.

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Herrán, Sara, Patricia Zorrilla, and Irene Rodríguez. "Intento autolítico con sobredosis de paracetamol." In 31 Congreso Nacional de Medicina General y de Familia. Grupo Pacífico, 2025. https://doi.org/10.48158/semg25-417.

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Manzotti de Souza, Fernando, Gabriela Nascimento Silva, Melissa Gurgel Adeodato Vieira, and Onélia Aparecida Andreo dos Santos. "Adsorção de Paracetamol em Argilas Bentoníticas Organomodificadas." In Simpósio de Bioquímica e Biotecnologia. Galoa, 2017. http://dx.doi.org/10.17648/simbbtec-2017-80793.

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Pérez, Marina, Marta Freire, María Ramos, et al. "NEFROPATÍA AGUDA INDUCIDA POR PARACETAMOL SIN HEPATOTOXICIDAD." In 38 Congreso Nacional de la Sociedad Española de Pediatría y Atención Primaria - SEPEAP 2024. Grupo Pacífico, 2024. http://dx.doi.org/10.48158/sepeap2024.o015.

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Hetherington, Lauren, Emma Watson, and David Graham. "7995 Enteral paracetamol dosing in overweight children." In Royal College of Paediatrics and Child Health, Abstracts of the RCPCH Conference, Glasgow, 26 March 2025 – 28 March 2025. BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health, 2025. https://doi.org/10.1136/archdischild-2025-rcpch.127.

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Reports on the topic "Paracetamol"

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Sentcоv, Valentin, Andrei Reutov, and Vyacheslav Kuzmin. Electronic training manual "Acute drug poisoning". SIB-Expertise, 2024. http://dx.doi.org/10.12731/er0776.29012024.

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The widespread use in modern medicine of hypnotics, sedatives, tricyclic antidepressants, antihypertensive drugs and antipyretics, even in therapeutic dosages, sometimes leads to adverse consequences for the patient. Accidental or intentional excess of therapeutic dosages leads to severe poisoning. This fact indicates the high relevance of doctors’ knowledge of any clinical specialty and the treatment of poisoning by these groups of drugs. This electronic educational resourse consists of six theoretical educational modules: poisoning with barbituric acid derivatives, acute poisoning with tricy
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พนมวัน ณ อยุธยา, ดวงจิต, ปฏิภาณ พนมวัน ณ อยุธยา та อภิฤดี เหมะจุฑา. การสำรวจการใช้ยาของโรงพยาบาล มหาวิทยาลัยในกรุงเทพมหานครระหว่าง พ.ศ. 2523-2525 : รายงานผลการวิจัย. จุฬาลงกรณ์มหาวิทยาลัย, 1985. https://doi.org/10.58837/chula.res.1985.14.

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The top 200 drug products most frequently dispensed in the university hospitals in Bangkok during 1980 to 1982 were identified and ranked. Paracetamol was ranked number one with the highest number of tablets dispensed while Ampicillin was ranked number one with the highest value dispensed. The top 200 drug products accounted for approximately 82 percent of the total value of drug dispensed in a year. At the same time, the drugs were classified according to their pharmacological action. Penicillins was the sub-pharmacological class with the highest value dispensed which accounted for approximat
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Chou, Roger, Azrah Y. Ahmed, Tracy Dana, et al. Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain: 2024 Update. Agency for Healthcare Research and Quality (AHRQ), 2024. https://doi.org/10.23970/ahrqepccer250.2024update.

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Objectives. To update the evidence on benefits and harms of cannabinoids and other plant-based compounds to treat subacute and chronic pain in adults and adolescents using a living systematic review approach. Data sources. Ovid® MEDLINE®, PsycINFO®, Embase®, the Cochrane Library, and SCOPUS® databases, and reference lists of included studies were searched to June 30, 2024. Review methods. We grouped studies based on their tetrahydrocannabinol (THC) to cannabidiol (CBD) ratio and by product type: synthetic, purified (plant-derived product consisting of a single cannabinoid, e.g., dronabinol or
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Paracetamol may be ineffective in treating lower back pain. National Institute for Health Research, 2015. http://dx.doi.org/10.3310/signal-000102.

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Paracetamol is a weak painkiller for regular tension headaches. National Institute for Health Research, 2016. http://dx.doi.org/10.3310/signal-000299.

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Diclofenac or etoricoxib, but not paracetamol, is effective for treating osteoarthritis. National Institute for Health Research, 2016. http://dx.doi.org/10.3310/signal-000245.

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Paracetamol and alcohol are the most common substances taken by young people and rates of poisoning are increasing. National Institute for Health Research, 2018. http://dx.doi.org/10.3310/signal-000694.

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