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Dissertations / Theses on the topic 'Paracetamol'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Mohd, Zaki Hamizah. "Spectroscopy surface analysis of paracetamol and paracetamol and excipient systems." Thesis, University of Manchester, 2011. https://www.research.manchester.ac.uk/portal/en/theses/spectroscopy-surface-analysis-of-paracetamol-and-paracetamol-and-excipient-systems(2f50af69-fb35-487b-8065-46aa3c86f96c).html.

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A detailed, fundamental understanding of the surface properties of molecular crystals and their interaction with adsorbing molecules (e.g. excipients) is important for tailoring the stability of formulations and the bioavailability of Active Pharmaceutical Ingredient (APIs). Few fundamental experimental studies with surface sensitive probes have been carried out for organic molecular crystals. X-ray photoelectron spectroscopy (XPS) is an established surface analysis method in the fields of adsorption, catalysis and surface chemistry of inorganic crystals. It has high surface sensitivity, probi

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2

Castro, Pedro Luís Pereira de. "Farmacocinética do paracetamol." Master's thesis, [s.n.], 2014. http://hdl.handle.net/10284/4415.

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Projeto de Pós-Graduação/Dissertação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Ciências Farmacêuticas<br>O paracetamol é um dos analgésicos e antipiréticos mais utilizados em crianças e adultos por possuir uma janela terapêutica larga com poucos efeitos adversos. No entanto, por ser um medicamento não sujeito a receita médica, é por vezes utilizado em sobredosagem, podendo provocar hepatotoxicidade decorrente do esgotamento dos níveis de glutationa hepática e do excesso de produção de N-acetil-p-benzoquinonaimina (NAPQI), um metabol

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3

Robinson, D. "Factors influencing paracetamol overdose." Thesis, Queen's University Belfast, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.403484.

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4

Flodell, Amanda. "Risker vid användning av paracetamol under graviditet : Risker vid användning av paracetamol under graviditet." Thesis, Umeå universitet, Kemiska institutionen, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-102007.

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5

Cabral, Flavia Helena Costa. "Alterações morfologicas testiculares provocadas pelo cadmio, paracetamol e cadmio associado ao paracetamol, em ratos." [s.n.], 1996. http://repositorio.unicamp.br/jspui/handle/REPOSIP/317850.

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Orientador: Mary Anne Heidi Dolder<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Biologia<br>Made available in DSpace on 2018-07-21T09:40:36Z (GMT). No. of bitstreams: 1 Cabral_FlaviaHelenaCosta_M.pdf: 7932022 bytes, checksum: 5df8caed27891d2ed2c74e69d6748a6b (MD5) Previous issue date: 1996<br>Resumo: O cádmio é um elemento químico, reconhecido atualmente como perigoso devido sua alta toxicidade e os efeitos deletérios que provoca nos seres vivos. Recentemente também tem sido investigadas com maior interesse e atenção, algumas drogas vendidas sem prescrições méd

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6

Chiew, Angela. "Changing paradigms of paracetamol poisoning." Thesis, University of Sydney, 2020. https://hdl.handle.net/2123/23382.

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The overall objective of this thesis was to identify and examine areas for improvement in the management of paracetamol poisoning. Paracetamol is one of the commonest drugs taken in overdose in Australia and a common cause of acute liver injury in Western countries. Management of paracetamol poisoning includes assessment for the need of antidote (acetylcysteine) administration and decontamination in patients at risk of toxicity. Management in most follows standard guidelines and in those receiving early acetylcysteine are at very low risk of developing acute liver injury. However, circumstance

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7

Arakji, Jawad Ola. "Effekter av begränsad förpackningsstorlek för paracetamol." Thesis, Umeå universitet, Farmakologi, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-121837.

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8

SCIEUX, PIERRE. "Intoxication par le paracetamol chez l'adulte." Lille 2, 1989. http://www.theses.fr/1989LIL2M033.

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9

Bashir, Shazma. "Mechanism of Paracetamol (acetaminophen) induced hypothermia." Thesis, University of East London, 2018. http://roar.uel.ac.uk/7308/.

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Paracetamol is a potent analgesic and antipyretic with limited side effects compared to the nonsteroidal anti-inflammatory drugs (NSAIDs) and opiates. Worldwide paracetamol is commonly used to treat pain and fever in both children and adults. Although, this drug has been in clinical use for more than a century, the mechanisms of action are not fully understood. Historically some of the actions of paracetamol were attributed to the inhibition of central cyclooxygenase (COX-1 and COX-2) enzymes however given the weak inhibitory effects on COX-1 and COX-2 enzymes, alternative targets have been su

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10

Chevallier, Thierry. "Pharmacologie clinique du paracetamol en collyre." Nice, 1992. http://www.theses.fr/1992NICE6556.

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11

Pakravan, Nasrin. "Paracetamol poisoning and its treatment in man." Thesis, University of Edinburgh, 2008. http://hdl.handle.net/1842/4292.

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Paracetamol is the most common drug taken in overdose in the UK. Although it has been used in overdose for about 50 years, there are many aspects of its toxicity and treatment that are not fully understood. In this thesis a series of related studies on paracetamol overdose are reported. The nephrotoxic effects of paracetamol in overdose have long been recognised. To better understand the mechanisms of this effect the effect of acute paracetamol overdose on plasma electrolytes were investigated, both retrospectively and, more intensively, prospectively. The results of these studies showed parac

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12

Godfrey, Lisa. "Interactions between paracetamol and caffeine in mice." Thesis, University of Surrey, 2005. http://epubs.surrey.ac.uk/826/.

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13

Kamali, F. "Metabolism and pharmacokinetics of paracetamol in man." Thesis, University of Nottingham, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.355292.

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14

Costa, Odeize Viana. "MULTIPLICIDADE ESTRUTURAL DO PARACETAMOL NO ESTADO SÓLIDO." Pontifícia Universidade Católica de Goiás, 2009. http://localhost:8080/tede/handle/tede/2116.

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Made available in DSpace on 2016-08-10T10:29:35Z (GMT). No. of bitstreams: 1 ODEIZE VIANA COSTA.pdf: 5283197 bytes, checksum: 973307d642e08455a57776a4b12a6d0d (MD5) Previous issue date: 2009-07-03<br>The theme of this study focused on polymorphisms of Paracetamol in the solid state. So, before the constant use of Paracetamol in Pharmacology and Chemistry in general, it justify studies that more about, its composition and its variations in the solid state. It is concluded that the technical analysis of polymorphism of the drug Paracetamol, as well as others, shows different structural aspects

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15

Keeble, Julie Elizabeth. "The cardiovascular effects and catabolism of NO NSAIDS and other NO releasing adduct drugs." Thesis, King's College London (University of London), 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.246315.

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16

DEAUX, JEAN-LOUIS. "Intoxication aigue au paracetamol : bilan de 6 ans d'appels au centre anti-poisons : de 1982 a 1987." Toulouse 3, 1988. http://www.theses.fr/1988TOU31352.

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17

CAMUT, LIONEL. "Intoxication aigue par le paracetamol : etude de 162 observations." Angers, 1989. http://www.theses.fr/1989ANGE1093.

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18

Honhold, Nick. "Paracetamol, percutaneous electrical stimulation and rat spinal neurones." Thesis, Royal Veterinary College (University of London), 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.522587.

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19

Possamai, Lucia. "Susceptibility factors in paracetamol-induced acute liver failure." Thesis, Imperial College London, 2015. http://hdl.handle.net/10044/1/25269.

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Paracetamol is a popular antipyretic and analgesic medication. It is a known hepatotoxin in overdose and is the commonest cause of acute liver failure in the UK. There is significant variability in inter-individual susceptibility to the hepatotoxic effects of paracetamol, which is incompletely understood. This thesis describes work done in murine models of paracetamol-induced acute liver failure with the aim of identifying causes of variable susceptibility and understanding the immune response to liver injury. A quantitative trait locus (QTL) mapping approach was taken using a murine strain su

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20

Barraza, Góngora Carlos. "Interacción dexibuprofeno con paracetamol en formalina orofacial experimental." Tesis, Universidad de Chile, 2009. http://repositorio.uchile.cl/handle/2250/134478.

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Trabajo de Investigación Requisito para optar al Título de Cirujano Dentista<br>El dolor corresponde a una de las principales causas de consulta en la clínica odontológica. Para el manejo del dolor, los clínicos contamos con una gran variedad de fármacos, entre los cuales destacan los antiinflamatorios no esteroidales (AINEs), drogas que por regla general, poseen mecanismos de acción y efectos adversos comunes. Para contrarrestar las reacciones adversas, se han realizado una gran cantidad de estudios, que han permitido el desarrollo o mejoras de ciertos fármacos. Como resultado de estas

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21

Di, Martino Piera. "Polymorphisme du paracetamol : application a la compression directe." Lille 2, 1996. http://www.theses.fr/1996LIL2P257.

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22

Elijošius, Evaldas. "Kramtomųjų paracetamolio tablečių vaikams technologija." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2011. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2011~D_20110628_155329-47227.

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Šiuo metu Lietuvoje pramoniniu būdu gaminamų farmacinių formų vaikams kiekis yra ribotas (2009/2010m. Lietuvos Respublikos Vaistinių preparatų registro duomenimis). Atlikus eilę studijų, buvo nutarta sukurti kramtomųjų paracetamolio tablečių vaikams gamybos technologiją. Surinkome ir susisteminome duomenis apie galimus technologinius tablečių gamybos variantus. Ištyrėme paracetamolio ir pasirinktų pagalbinių medžiagų technologines savybes. Išanalizavome mokslinius duomenis apie granuliacijos metodus bei technologinius tabletavimo būdus. Nustatytos reikiamos miltelių technologinės savybės, pari

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23

Ciegis, Paulius. "Alprazolamo, kodeino ir paracetamolio mišinio kokybinė analizė plonasluoksnės ir efektyviosios skysčių chromatografijos metodais." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2014. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2014~D_20140618_233534-96441.

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Darbo tikslas: Optimizuoti plonasluoksnės chromatografijos ir efektyviosios skysčių chromatografijos metodikas, tinkamas alprazolamo, kodeino ir paracetamolio kokybiniam įvertinimui. Tyrimo objektas ir metodai: Optimizuojant PC metodiką, analizuoti etaloniniai 0,2 mg/ml koncentracijos alprazolamo, kodeino, paracetamolio trichlormetaniniai tirpalai ir jų mišinys. Tirpiklių sistemoms buvo naudoti etanolis, trichlormetanas, eteris, 25% amonio hidroksidas, acetonas, izobutanolis. Dėmių ryškinimui naudota UV šviesos (254nm; 365nm) lempa arba Dragendorfo reagentas (modifikuotas pagal Munjė). Optimiz

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24

KAMINSKI, PASCAL. "Ingestion accidentelle de paracetamol chez l'enfant : etude retrospective : a propos de 38 observations." Lille 2, 1988. http://www.theses.fr/1988LIL2M359.

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25

Barthèlemy, Pierre. "Reflexions sur l'apport du paracetamol dans le traitement de la douleur." Saint-Etienne, 1994. http://www.theses.fr/1994STET6230.

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26

Bravo, Castelblanco Camila Victoria. "Interacción de gabapentina con paracetamol en dolor orofacial experimental." Tesis, Universidad de Chile, 2013. http://www.repositorio.uchile.cl/handle/2250/117625.

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Trabajo de Investigación Requisito para optar al Título de Cirujano Dentista<br>Introducción: Para el manejo del dolor orofacial de tipo neuropático se dispone de una amplia gama de medicamentos, entre estos encontramos antinflamatorios no esteroidales (AINES), anticonvulsivantes y opioides. La analgesia multimodal es actualmente recomendada para aumentar la utilidad clínica de los analgésicos e implica la combinación de diversos fármacos con diferentes mecanismos de acción, lo que resulta en efectos aditivos o supraditivos. El objetivo del actual estudio, es evaluar el efecto analgésico

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27

Ålander, Eva. "Influence of solvent composition on crystal agglomeration of paracetamol /." Stockholm, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-198.

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28

Greenough, Carrie Louise. "The pharmacological and proteomic characterisation of paracetamol-induced hepatotoxicty." Thesis, University of Liverpool, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.423015.

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29

El-Hassan, Hasan. "Apoptosis and liver disease : its role in paracetamol hepatotoxicity." Thesis, University of Surrey, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.402937.

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30

McGregor, Angus H. "Liver death and regeneration : indirect mechanisms of paracetamol toxicity." Thesis, University of Edinburgh, 2003. http://hdl.handle.net/1842/24945.

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Background: Paracetamol overdose (POD) remains a pressing clinical problem as despite the availability of a safe and effective antidote, patients continue to die or require a liver transplant. Recent evidence suggests that toxicity after POD may be more than a simple direct toxic effect as has previously been accepted and that Kupffer cells and cytokine4s such as TNF-a are involved in the pathogenesis of liver injury. Paracetamol and Hepatocyte Apoptosis Examination of liver in patients after POD revealed hepatocyte apoptosis occurring alongside striking regenerative activity. Apoptosis is imp

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31

Garay, Sepúlveda Carlos Roberto. "Asociación de paracetamol con naproxeno en dolor orofacial experimental." Tesis, Universidad de Chile, 2010. http://repositorio.uchile.cl/handle/2250/133798.

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Trabajo de Investigación Requisito para optar al Título de Cirujano Dentista<br>Introducción: Los fármacos más usados en el tratamiento farmacológico del dolor son principalmente los opioides y los analgésicos antiinflamatorios no esteroidales (AINEs). En este estudio se evaluará la actividad analgésica del paracetamol, del naproxeno y de su combinación. Como método algesiométrico en este trabajo se usará el de la formalina orofacial. Material y Método: Se utilizaron 110 ratones Mus musculus cepa CF/1 a los que se les inyectó solución salina de paracetamol, naproxeno y su combinación

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32

Medel, García Gonzalo. "Asociación de dexketoprofeno y paracetamol en dolor orofacial experimental." Tesis, Universidad de Chile, 2011. http://repositorio.uchile.cl/handle/2250/133576.

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Trabajo de Investigación Requisito para optar al Título de Cirujano Dentista<br>INTRODUCCION: Las drogas más usadas en el tratamiento farmacológico del dolor son principalmente los analgésicos antiinflamatorios no esteroidales (AINEs) y los opioides. En este estudio se evaluó la actividad analgésica del paracetamol, del dexketoprofeno y de su combinación. Para medir esta actividad se ocupó el test de formalina orofacial. MATERIALES Y METODO: Se utilizaron 162 ratones machos de la cepa CF/1 (Mus musculus), a los que se les inyectó intraperitonealmente una solución salina de paracetamo

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33

Garekani, Hadi Afrasiabi. "The characterization and compaction properties of manipulated paracetamol crystals." Thesis, Liverpool John Moores University, 1996. http://researchonline.ljmu.ac.uk/5131/.

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34

Kane, Alice Elizabeth. "Paracetamol Toxicity: Influence Of Ageing, Frailty, Resveratrol And Sirt1." Thesis, The University of Sydney, 2015. http://hdl.handle.net/2123/14966.

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The objective of this thesis was to help improve the safety of paracetamol for patients of all ages by adding evidence to the body of knowledge on the changing risks of paracetamol toxicity in ageing, frailty and non-acute exposures, and the potential for lifespan and healthspan increasing interventions to provide novel mechanisms of paracetamol hepatotoxicity protection. Furthermore, this thesis aimed to investigate the potential of both paracetamol, and lifespan and healthspan interventions in delaying or preventing frailty. Overall the work presented in this thesis used a series of mouse mo

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Raimundo, Mariana Peres Navarro. "Ensaio clínico para avaliação do benefício da administração peri-operatória de paracetamol em cães submetidos a extração dentária." Master's thesis, Universidade de Lisboa, Faculdade de Medicina Veterinária, 2019. http://hdl.handle.net/10400.5/19210.

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Dissertação de Mestrado Integrado em Medicina Veterinária<br>O paracetamol é um analgésico, antipirético e fraco anti-inflamatório, amplamente utilizado em Medicina Humana e que pode ser utilizado no maneio da dor peri-operatória no cão. Apesar de apresentar uma janela terapêutica reduzida, o seu uso tem aumentado por ter efeitos adversos gastrointestinais e renais negligenciaveis e não possuir efeito antiagregante plaquetário. A hepatotoxicidade ocorre, no entanto, em casos de sobredosagem, o que pode acontecer com alguma facilidade no contexto de uso sem recomendação médico-veterinária. O o

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Kalakech, Carla. "Membrane crystallization by pervaporation for paracetamol production and polymorphism control." Electronic Thesis or Diss., Lyon 1, 2024. http://www.theses.fr/2024LYO10300.

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La cristallisation est une opération unitaire cruciale en ingénierie des procédés, largement utilisée dans des secteurs tels que la chimie, la pharmacie et l'électronique. Malgré son importance, les méthodes actuelles de cristallisation rencontrent diverses limitations, affectant la qualité du produit final, la constance de la production et le contrôle de la forme polymorphique. Récemment, les procédés membranaires sont apparus comme une approche prometteuse pour améliorer le contrôle de la cristallisation, en particulier la pervaporation, qui utilise une membrane dense ou composite sélective.

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Fuentes, Anabalón Edgardo. "Evaluación antinociceptiva entre paracetamol y parecoxib en dolo agudo experimental." Tesis, Universidad de Chile, 2006. http://repositorio.uchile.cl/handle/2250/110752.

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Sepúlveda, Encina Andrés Esteban. "Interacción antinociceptiva de paracetamol con tramadol en dolor orofacial experimental." Tesis, Universidad de Chile, 2010. http://repositorio.uchile.cl/handle/2250/134412.

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Trabajo de Investigación Requisito para optar al Título de Cirujano Dentista<br>Autor no autoriza el acceso a texto completo de su documento<br>Los fármacos más utilizados como analgésicos son los AINEs y los opioides. En el presente trabajo se investigó la actividad nociceptiva e interacción de tramadol (opioide) con paracetamol (AINE) en el ensayo algesiométrico de la formalina orofacial. Se utilizaron ratones a los cuales se les inyectó, en la región labial, 20 µl de solución de formalina al 2%, midiéndose el tiempo de frotamiento de la zona, durante los 5 minutos inmediatos a la inyec

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Bisson, Marcelo Polacow. "Estudo dos efeitos analgesicos do paracetamol em diferentes modelos experimentais." [s.n.], 1991. http://repositorio.unicamp.br/jspui/handle/REPOSIP/290312.

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Orientadores : Samir Tufic Arbex, Gloria Emilia Petto de Souza<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba<br>Made available in DSpace on 2018-07-13T23:11:30Z (GMT). No. of bitstreams: 1 Bisson_MarceloPolacow_M.pdf: 2951044 bytes, checksum: 514a26fd9aad87cfbad7326397a4e525 (MD5) Previous issue date: 1991<br>Resumo: o presente trabalho leve como finalidade. veriricar alguns aspectos relacionados à posslvel ação analgésica central do paracetamol, em roedores. Para isto foram empregados quatro modelos de estudo distintos: 1 - Teste de c

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CASTAÑEDA, JUAREZ MONSERRAT 622426, and JUAREZ MONSERRAT CASTAÑEDA. "Remoción de diclofenaco y paracetamol por procesos de oxidación avanzada." Tesis de doctorado, UNIVERSIDAD AUTÓNOMA DEL ESTADO DE MÉXICO, 2020. http://hdl.handle.net/20.500.11799/105682.

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En el capítulo 1 se abordan las propiedades químicas de ambos fármacos, la problemática ambiental y a la salud humana que representan, así como el estado del arte acerca de los POA que han sido aplicados en cada caso. En el capítulo 2 se describen los pasos que se realizaron para cada uno de los sistemas de tratamiento, los métodos y tecnologías desarrollados; en general, las variables que se deben considerar para seleccionar un POA son la dosis del oxidante y/o catalizador, la concentración inicial del contaminante, el pH y la temperatura. Fueron aplicados diversos métodos estadísticos para e

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Fachaux, Jean-Michel. "Un paracetamol pur pour compression directe : obtention par solvation/desolvation." Lille 2, 1995. http://www.theses.fr/1995LIL2P269.

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Pålsson, Lilja Malin, and Simic Emma Doverbäck. "Skolsköterskors uppfattning om användande av paracetamol bland elever i grundskola." Thesis, Högskolan i Skövde, Institutionen för hälsa och lärande, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-13869.

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Bakgrund: Barn nyttjar paracetamol på ett sätt som medför risker för barnets hälsa En del barn är inte medvetna om varför de har ont, utan självmedicinerar med paracetamolpreparat. Syfte: Att belysa skolsköterskors uppfattning om användande av substansen paracetamol bland elever i grundskola. Metod: Studien genomfördes med en kvalitativ metod med en fenemenografisk analys, genom e-post intervjuer med skolsköterskor i årskurs förskoleklass till 9. Resultat: Studiens resultat visar att skolsköterskor som arbetar i grundskola uppfattar att elever, främst i högstadieskola, självmedicinerar somatis

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43

Solano, Mendez Alejandra. "“EFICACIA ANALGÉSICA EN COLECISTECTOMIA LAPAROSCÓPICA USANDO COMBINACION DE PARACETAMOL MAS DICLOFENACO VS PARACETAMOL MAS CLONIXINATO DE LISINA EN EL HOSPITAL GENERAL DE ATIZAPAN DURANTE EL PERIODO ENERO A DICIEMBRE DEL 2013”." Tesis de Licenciatura, Medicina-Quimica, 2014. http://ri.uaemex.mx/handle/123456789/14458.

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Objetivo: Evaluar la eficacia analgésica posoperatoria al comparar la combinación de Paracetamol-Diclofenaco vs Paracetamol-Clonixinato de lisina, en pacientes sometidos a colecistectomía laparoscópica. Diseño: Ensayo clínico controlado, prospectivo, transversal, descriptivo y comparativo. Procedimientos: Se estudiaron un total de 90 pacientes, sometidos a colecistectomía laparoscópica manejados con anestesia general balanceada, y a los cuales se les administró un régimen de analgesia postquirúrgica, se dividieron en 3 grupos, al grupo 1 se administró Paracetamol 1g IV más Diclofenaco 7

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POUYET, ALAIN. "Chronopharmacocinetique du paracetamol chez le sujet age de plus de 70 ans : etude sur 10 cas." Aix-Marseille 2, 1990. http://www.theses.fr/1990AIX20281.

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Patel, Aadila. "Is paracetamol being prescribed and used at the correct therapeutic dose in the children population in South Africa?" Thesis, University of the Western Cape, 2014. http://hdl.handle.net/11394/4662.

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>Magister Scientiae - MSc<br>When used at the recommended and approved therapeutic dose, paracetamol is effective. Paracetamol is available in various forms and easily accessible from general dealers and pharmacies. The liquid form is the preferred form given with a device to children. Paracetamol is effective within a defined therapeutic range; however, are prescribers and caregivers using paracetamol as authorised by regulators? A qualitative review of product specific labelling and the department of health recommendations was conducted and evaluated by means of arithmetic means differences

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Makhafula, Lebone D. "Ibuprofen, paracetamol and tilidine; their role in post tonsillectomy pain at Dr George Mukhari Hospital." Thesis, University of Limpopo ( Medunsa Campus), 2011. http://hdl.handle.net/10386/791.

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Thesis (M Med(Otorhinolaryngology)) -- University of Limpopo, 2011.<br>Background: Tonsillectomy is one of the commonest operations performed by ENT surgeons. Pain, haemorrhage, delayed feeding and resumption of normal activities are common morbidities. Different groups of analgesics are used to reduce these morbidities. Objective: We examined the effectiveness of the use of three analgesics, some in combinations in reducing these morbidities. The primary outcome measures were pain, resumption of normal diet, resumption of normal physical activities and secondary haemorrhage. The secondary

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QIAO, CHUN-SHENG. "Mise au point d'une mousse rectale medicamenteuse : etude de formulation et etude pharmacocinetique." Strasbourg 1, 1989. http://www.theses.fr/1989STR13158.

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Une mousse aqueuse dans laquelle le paracetamol est en suspension et une mousse non aqueuse, dans laquelle le paracetamol est en solution dans du propylene glycol ont ete etudiees. Etudes pharmacocinetiques. Comparaison avec un suppositoire et un sachet pour la voie orale

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Godoy, Villanueva Claudia. "Interacción analgésica de paracetamol y nimesulida en dolor experimental térmico agudo." Tesis, Universidad de Chile, 2006. http://www.repositorio.uchile.cl/handle/2250/110754.

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Trabajo de Investigación Requisito para optar al Título de Cirujano Dentista<br>El dolor y sintomatología de cuadros inflamatorios crónicos o agudos, es de gran importancia para su estudio y tratamiento. Existen una variedad de fármacos utilizados para este último fin. Dentro de ellos están los AINEs, que inhiben la producción de prostaglandinas por el bloqueo de las enzimas que las sintetizan: ciclooxigenasas (COXs). Con el afán de encontrar mejores soluciones terapéuticas, se ha explorado interacciones entre AINEs, que sean de tipo sinérgico, con el objetivo de una te

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Silva, Junior Nelson Pereira da [UNESP]. "Avaliação de processos para obtenção de comprimidos de Beta-Ciclodextrina-Paracetamol." Universidade Estadual Paulista (UNESP), 2006. http://hdl.handle.net/11449/91705.

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Made available in DSpace on 2014-06-11T19:25:27Z (GMT). No. of bitstreams: 0 Previous issue date: 2006-07-28Bitstream added on 2014-06-13T19:12:10Z : No. of bitstreams: 1 silvajunior_np_me_arafcf.pdf: 678354 bytes, checksum: 4f229eb833483c2108d5ca9ff0af89b6 (MD5)<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)<br>Universidade Estadual Paulista (UNESP)<br>Ciclodextrinas (CD) têm sido relatadas em inúmeros estudos por interagir com muitos fármacos para a formação de complexos de inclusão com o objetivo de aumentar a solubilidade, estabilidade e biodisponibilidade. No pro

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Bruschi, Sam A. "Investigations into mechanisms of paracetamol-induced toxicity using ìn vitro' systems /." Title page, abstract and table of contents only, 1987. http://web4.library.adelaide.edu.au/theses/09PH/09phb192.pdf.

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