Log in

Relevant bibliographies by topics / Pharmaceuticals preparations / Dissertations / Theses

To see the other types of publications on this topic, follow the link: Pharmaceuticals preparations.

Dissertations / Theses on the topic 'Pharmaceuticals preparations'

Author: Grafiati

Published: 28 May 2022

Last updated: 31 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 dissertations / theses for your research on the topic 'Pharmaceuticals preparations.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse dissertations / theses on a wide variety of disciplines and organise your bibliography correctly.

1

Pramanick, Papun. "Effective approaches to minimize the problem of pharmaceuticals and other personal care products in the environment /." Online version of thesis, 2007. http://hdl.handle.net/1850/5970.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Rehman, Faridi Shah Mohammad Hamoodur. "Artificial Intelligence Based Real-Time Processing of Sterile Preparations Compounding." University of Toledo / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1596595453534505.

Full text

APA, Harvard, Vancouver, ISO, and other styles

3

Петльована, Л. С. "Особливості маркетингу на фармацевтичному підприємстві". Thesis, Сумський державний університет, 2016. http://essuir.sumdu.edu.ua/handle/123456789/49313.

Full text

Abstract:

За останні роки ситуація на фармацевтичному ринку різко змінилася. Кількість виробників лікарських препаратів стрімко збільшується, конкуренція зростає. Іноземні виробники виходять на ринок, та заміщують вітчизняні фармацевтичні підприємства. Виходячи з цього, досить важливого значення набуває відділ маркетингу на підприємстві, та використання маркетингу в цілому для утримання міцних позицій на ринку. Поняття фармацевтичного маркетингу дещо відрізняється від загального.

APA, Harvard, Vancouver, ISO, and other styles

4

Hedeland, Ylva. "Chiral Separation of Amines by Non-Aqueous Capillary Electrophoresis using Low Molecular Weight Selectors." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Universitetsbiblioteket [distributör], 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-6759.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

Wang, Ban. "Synthesis of Bis(imino)pyridine Iron(II) Complexes and Development of Bis(imino)pyridine Iron(II) Catalyzed Carbene Transfer Reactions." TopSCHOLAR®, 2019. https://digitalcommons.wku.edu/theses/3159.

Full text

Abstract:

Metal catalysis of symmetric and asymmetric carbene transfer reactions has been widely applied in natural product synthesis and material science over years. Metal carbene can be easily generated from the extrusion of nitrogen under the catalysis of metal complexes to further undergo various organic reactions, O/N/C-H insertions, cycloadditions, and ylide formations. Currently, the dominant effective catalysts for carbene reactions are built with expensive precious metal, for example, rhodium, ruthenium, palladium, gold. Notably, the effective reactivity and enantioselectivity of the dirhodium(

APA, Harvard, Vancouver, ISO, and other styles

6

Östlund, Martin. "AssistancePlus : 3D-mediated advice-giving on pharmaceutical products /." Linköping : Department of Computer and Information Science, Linköpings universitet, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-12159.

Full text

APA, Harvard, Vancouver, ISO, and other styles

7

Karki, Shyam. "Pharmaceutical cocrystals : preparation and properties." Thesis, University of Cambridge, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.611636.

Full text

APA, Harvard, Vancouver, ISO, and other styles

8

Bronkhorst, Elmien. "An Assessment of the need of pharmaceutical services in the intensive care unit and high care unit of Steve Biko Academic hospital." Thesis, University of Limpopo (Medunsa Campus), 2012. http://hdl.handle.net/10386/1081.

Full text

Abstract:

Thesis (MSc(Med)(Pharmacy)) -- University of Limpopo, 2012.<br>The role of the pharmacist has evolved over the last two decades beyond the traditional functions of dispensing and stock control. The focus has shifted toward patient-oriented functions, in which the pharmacist assumes responsibility for the patient’s drug- and healthcare needs as well as the outcome of treatment. The aim of this research was to assess the need for pharmaceutical care to the Surgical Intensive Care Unit of Steve Biko Hospital. The surgical and trauma ICU is a 12 bed unit to which the researcher rendered phar

APA, Harvard, Vancouver, ISO, and other styles

9

Wierik, Gerrit H. te. "Preparation, characterization and pharmaceutical application of linear dextrins /." [S.l. : s.n.], 1993. http://www.gbv.de/dms/bs/toc/144431122.pdf.

Full text

APA, Harvard, Vancouver, ISO, and other styles

10

Patel, Kush. "Preparation and Characterization of Insulin loaded Calcium Alginate Nanoparticles." University of Toledo Health Science Campus / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=mco1404662134.

Full text

APA, Harvard, Vancouver, ISO, and other styles

11

Velaga, Sitaram P. "Preparation of Pharmaceutical Powders using Supercritical Fluid Technology : Pharmaceutical Applications and Physicochemical Characterisation of Powders." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4006.

Full text

APA, Harvard, Vancouver, ISO, and other styles

12

Patel, Bhavnita. "Pharmaceutical co-amorphous materials and cocrystals : preparation and analysis." Thesis, University of Cambridge, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.648098.

Full text

APA, Harvard, Vancouver, ISO, and other styles

13

Alabbas, Alhumaidi B. "GLYCOSAMINOGLYCAN LYASES IN THE PREPARATION OF OLIGOSACCHARIDES." VCU Scholars Compass, 2018. https://scholarscompass.vcu.edu/etd/5279.

Full text

Abstract:

Glycosaminoglycans are heterogeneous polysaccharides that mediate important biological functions. There has been considerable interest in deciphering the precise GAG sequences that are responsible for protein interactions. In fact, several GAG oligosaccharides have been discovered to date as targeting proteins with higher level of specificity. Yet, it has been difficult to develop GAG oligosaccharides as drugs. One of the key reasons for this state of art is that GAG synthesis is extremely challenging and is highly structure-specific. Thus, much of the biology and pharmacology of GAG remains u

APA, Harvard, Vancouver, ISO, and other styles

14

Fugit, Kyle Daniel. "QUANTIFICATION OF FACTORS GOVERNING DRUG RELEASE KINETICS FROM NANOPARTICLES: A COMBINED EXPERIMENTAL AND MECHANISTIC MODELING APPROACH." UKnowledge, 2014. http://uknowledge.uky.edu/pharmacy_etds/37.

Full text

Abstract:

Advancements in nanoparticle drug delivery of anticancer agents require mathematical models capable of predicting in vivo formulation performance from in vitro characterization studies. Such models must identify and incorporate the physicochemical properties of the therapeutic agent and nanoparticle driving in vivo drug release. This work identifies these factors for two nanoparticle formulations of anticancer agents using an approach which develops mechanistic mathematical models in conjunction with experimental studies. A non-sink ultrafiltration method was developed to monitor liposomal rel

APA, Harvard, Vancouver, ISO, and other styles

15

Frischkorn, Kate E. "Preparation of Supramolecular Amphiphilic Cyclodextrin Bilayer Vesicles for Pharmaceutical Applications." DigitalCommons@CalPoly, 2018. https://digitalcommons.calpoly.edu/theses/1894.

Full text

Abstract:

Recent pharmaceutical developments have investigated using supramolecular nanoparticles in order to increase the bioavailability and solubility of drugs delivered in various methods. Modification of the carbohydrate cyclodextrin increases the ability to encapsulate hydrophobic pharmaceutical molecules by forming a carrier with a hydrophobic core and hydrophilic exterior. Guest molecules are commonly added to these inclusion complexes in order to add stability and further increase targeting abilities of the carriers. One such guest molecule is adamantine combined with a poly(ethylene glycol) ch

APA, Harvard, Vancouver, ISO, and other styles

16

Bonam, Sindhu Prabha. "Preparation and Evaluation of Pluronic Lecithin Organogel Containing Ricinoleic acid for Transdermal Drug Delivery." University of Toledo Health Science Campus / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=mco1384437353.

Full text

APA, Harvard, Vancouver, ISO, and other styles

17

Bui, Thu-Tam T. "A pharmaceutical risk management model." Oklahoma City : [s.n.], 2006.

Find full text

APA, Harvard, Vancouver, ISO, and other styles

18

Princiotto, S. "Synthesis of intermediates for the preparation of Active Pharmaceutical Ingredients (APIs)." Doctoral thesis, Università di Siena, 2020. http://hdl.handle.net/11365/1095607.

Full text

Abstract:

Maytansinoids are ansa macrocycles extracted from shrubs of Maytenus ovatus. Their anticancer activity is known since the 1970s, but it could be possible to be exploited only recently, as conjugated to different antibody in the context of antibody drug conjugates (ADCs). This kind of approach allowed to drive the pharmacologically active compound (payload) selectively towards the target cancer cells, avoiding to exert the cytotoxicity also in healthy cells. Ansamitocin P3, isolated from fermentation of Actinosynnema pretiosum, is a useful precursor for the preparation of DM1, the payload prese

APA, Harvard, Vancouver, ISO, and other styles

19

Enlund, Anna Maria. "Capillary electroseparations in pharmaceutical analysis of basic drugs and related substances." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2001. http://w3.ub.uu.se/fulltext/91-554-4908-5.pdf.

Full text

APA, Harvard, Vancouver, ISO, and other styles

20

Mannheimer, Buster. "Drug-related problems with special emphasis on drug-drug interactions." Stockholm : Department of Clinical Science and Education, Karolinska Institutet, 2009. http://diss.kib.ki.se/2009/978-91-7409-602-6/.

Full text

APA, Harvard, Vancouver, ISO, and other styles

21

Dong, Liang-Chang. "Thermally reversible hydrogels for controlled drug delivery and enzyme immobilization /." Thesis, Connect to this title online; UW restricted, 1990. http://hdl.handle.net/1773/8009.

Full text

APA, Harvard, Vancouver, ISO, and other styles

22

El, Masri Sarah. "Low transition temperature mixtures based on cyclodextrins as solubilizing vehicles in pharmaceutical preparations." Electronic Thesis or Diss., Littoral, 2024. https://documents.univ-littoral.fr/access/content/group/50b76a52-4e4b-4ade-a198-f84bc4e1bc3c/BULCO/Th%C3%A8ses/Toxicologie/122040_EL_MASRI_2024_archivage.pdf.

Full text

Abstract:

L'amélioration de la solubilité est un aspect critique dans la formulation et le développement de nouvelles molécules thérapeutiques. Pour surmonter les défis associés à une faible solubilité, les chercheurs ont évalué de nombreuses stratégies, dont l'utilisation de cyclodextrines et de cosolvants. Cette dernière approche est une technique simple et efficace, dans laquelle des solvants organiques sont utilisés pour améliorer la solubilité des composés peu solubles dans l'eau. Ces dernières années, les solvants eutectiques profonds (DESs) ont émergé comme une alternative abordable et verte comp

APA, Harvard, Vancouver, ISO, and other styles

23

Carlson, Paul Albin. "Lipid high-axial-ratio microstructures as pharmaceutical delivery systems : a physical characterization of the mechanisms behind drug release /." Thesis, Connect to this title online; UW restricted, 1999. http://hdl.handle.net/1773/8111.

Full text

APA, Harvard, Vancouver, ISO, and other styles

24

Lin, Yuh-Herng E. "Preparation and evaluation of poly (ortho esters) microspheres containing 5-fluorouracil." Scholarly Commons, 1998. https://scholarlycommons.pacific.edu/uop_etds/2331.

Full text

Abstract:

Microencapsulation of 5-fluorouracil was successfully accomplished with poly(ortho esters) polymer by emulsification-solvent evaporation method. While actual drug loading increased with increasing drug load (5 to 15% w/w), the entrapment efficiency remained essentially unaffected under a given set of experimental conditions. Incorporation of sorbitan sesquioleate enhanced entrapment efficiency, decreased the volume-surface mean diameter of the poly(ortho esters) microspheres and provided controlled release of 5-fluorouracil. The volume of aqueous phase was more important than the concentration

APA, Harvard, Vancouver, ISO, and other styles

25

Brown, Stacy D., Paul O. Lewis, Loren M. Kirk, and Yao Luu. "Stability of Commercially-Available Grape and Compounded Cherry Oral Vancomycin Preparations Stored in Syringes and Cups." Digital Commons @ East Tennessee State University, 2015. https://dc.etsu.edu/etsu-works/5275.

Full text

APA, Harvard, Vancouver, ISO, and other styles

26

Kalra, Ashish. "Preparation and Evaluation of Oil-in-Water Self-Nanoemulsifying Systems with Potential for Pulmonary Delivery." University of Toledo Health Science Campus / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=mco1364764383.

Full text

APA, Harvard, Vancouver, ISO, and other styles

27

Mahato, Ram Ishwar. "Preparation and characterisation of microparticulate drug delivery systems." Thesis, University of Strathclyde, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.296914.

Full text

APA, Harvard, Vancouver, ISO, and other styles

28

Zhang, Jinzhou. "Preparation and characterization of oxidized cellulose beads by extrusion/spheronization for chemoembolization." Diss., University of Iowa, 2013. https://ir.uiowa.edu/etd/2028.

Full text

Abstract:

Transarterial chemoembolization (TACE) has been practiced in patients for over 30 years and describes the infusion of chemotherapeutic agents followed by embolic particles. This infusion is normally performed by selecting tumor feeding arteries with a catheter under image guidance. The overall goal of TACE is to deliver a high dose of drug directly to a tumor, prevent drug clearance, and induce ischemic necrosis of the tumor. The limitations for current beads system including non-biodegradable and b

APA, Harvard, Vancouver, ISO, and other styles

29

Gupta, Patel Salin. "MECHANISMS AND THERMODYNAMICS OF THE INFLUENCE OF SOLUTION-STATE INTERACTIONS BETWEEN HPMC AND SURFACTANTS ON MIXED ADSORPTION ONTO MODEL NANOPARTICLES." UKnowledge, 2019. https://uknowledge.uky.edu/pharmacy_etds/103.

Full text

Abstract:

Nanoparticulate drug delivery systems (NDDS) such as nanocrystals, nanosuspensions, solid-lipid nanoparticles often formulated for the bioavailability enhancement of poorly soluble drug candidates are stabilized by a mixture of excipients including surfactants and polymers. Most literature studies have focused on the interaction of excipients with the NDDS surfaces while ignoring the interaction of excipients in solution and the extent to which the solution-state interactions influence the affinity and capacity of adsorption. Mechanisms by which excipients stabilize NDDS and how this informati

APA, Harvard, Vancouver, ISO, and other styles

30

Khairullah, Noor Hasnah Mohamed. "Preparation and characterisation of polymeric lamellar substrate particles (PLSP)." Thesis, University of Nottingham, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.252022.

Full text

APA, Harvard, Vancouver, ISO, and other styles

31

Singh, Priti. "A New Interfacial Cross Linking Technique: Preparation, Characterization and Evaluation of Calcium alginate Nanoparticles as a Protein Delivery System." University of Toledo Health Science Campus / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=mco1365434442.

Full text

APA, Harvard, Vancouver, ISO, and other styles

32

Tennant, Jason P. "Ectonucleotidase activity in smooth muscle preparations of the rat and guinea-pig." Thesis, University of Surrey, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.390571.

Full text

APA, Harvard, Vancouver, ISO, and other styles

33

Brown, Stacy. "Beyond-Use Dating of Lidocaine Alone and in Two “Magic Mouthwash” Preparations." Digital Commons @ East Tennessee State University, 2017. https://doi.org/10.2146/ajhp160214.

Full text

Abstract:

Purpose: Beyond-use dating (BUD) of lidocaine alone and in two “magic mouthwash” preparations stored in amber oral syringes at room temperature was determined. Methods:Two formulations of mouthwash containing oral topical lidocaine 2% (viscous), diphenhydramine 2.5 mg/mL, and aluminum hydroxide–magnesium hydroxide–simethicone were prepared in 1:1:1 and 1:2.5:2.5 ratios, divided into 3-mL samples, and stored in unit-dose oral amber syringes. Unit-dose single-product lidocaine samples were also prepared to serve as controls and stored in oral amber syringes. The lidocaine concentrations in these

APA, Harvard, Vancouver, ISO, and other styles

34

Weiß, Martin Steffen [Verfasser]. "Novel transaminases for the preparation of pharmaceutically relevant chiral amines / Martin Steffen Weiß." Greifswald : Universitätsbibliothek Greifswald, 2017. http://d-nb.info/1148439781/34.

Full text

APA, Harvard, Vancouver, ISO, and other styles

35

Ekelund, Mats. "Competition and innovation in the Swedish pharmaceutical market." Doctoral thesis, Stockholm : Economic Research Institute, Stockholm School of Economics (Ekonomiska forskningsinstitutet vid Handelshögsk.) (EFI), 2001. http://www.hhs.se/efi/summary/559.htm.

Full text

APA, Harvard, Vancouver, ISO, and other styles

36

Kirk, Loren M., Yao Luu, Stacy D. Brown, and P. O. Lewis. "Validated Chromatographic Method for Application Toward the Beyond-Use-Date Determination of Two Lidocaine Containing Mouthwash Preparations." Digital Commons @ East Tennessee State University, 2015. https://dc.etsu.edu/etsu-works/5274.

Full text

APA, Harvard, Vancouver, ISO, and other styles

37

Moore, William N. "Supercritical fluid extraction as a sample preparation technique for the isolation of polar pharmaceutical compounds." Diss., This resource online, 1996. http://scholar.lib.vt.edu/theses/available/etd-10052007-143203/.

Full text

APA, Harvard, Vancouver, ISO, and other styles

38

Chesi, Alexander. "Epileptiform activity in isolated cortex and hippocampal preparations, and its modulation by purinergic compounds." Thesis, University of Glasgow, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.296984.

Full text

APA, Harvard, Vancouver, ISO, and other styles

39

Osunmuyiwa, Y. "Preparation and characterisation of daunomycin-monoclonal antibody conjugates for cancer therapy." Thesis, University of Nottingham, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.332619.

Full text

APA, Harvard, Vancouver, ISO, and other styles

40

Allender, Christopher John. "Preparation, characterisation and novel applications for non-covalent molecular imprinted polymers." Thesis, Cardiff University, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.248323.

Full text

APA, Harvard, Vancouver, ISO, and other styles

41

Jones, Christine Elaine. "Preparation and characterisation of polymer films for the release of metronidazole." Thesis, University College London (University of London), 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.327574.

Full text

APA, Harvard, Vancouver, ISO, and other styles

42

McConnachie, Lisa A. "Effects of genotype and RNA expression on activity of cytochrome P450 2D6 : a highly polymorphic drug metabolizing enzyme /." Thesis, Connect to this title online; UW restricted, 2002. http://hdl.handle.net/1773/7973.

Full text

APA, Harvard, Vancouver, ISO, and other styles

43

Mandal, Bivash. "Preparation and Physicochemical Characterization of Eudragit® RL100 Nanosuspension with potential for Ocular Delivery of Sulfacetamide." University of Toledo / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1271430956.

Full text

APA, Harvard, Vancouver, ISO, and other styles

44

Niemeyer, Kathrin [Verfasser], and Ute [Akademischer Betreuer] Wittstock. "Ultrasonic methods for analytical determination of pancreatic enzyme activities in pharmaceutical preparations / Kathrin Niemeyer ; Betreuer: Ute Wittstock." Braunschweig : Technische Universität Braunschweig, 2012. http://d-nb.info/1175824062/34.

Full text

APA, Harvard, Vancouver, ISO, and other styles

45

Saliy, O. O. "Marketing researches of the countries-manufacturers preparations of hyaluronic acid." Thesis, ПАТ "Фармак", 2018. https://er.knutd.edu.ua/handle/123456789/13373.

Full text

Abstract:

The range of products with hyaluronic acid on the domestic market is very limited during the studied period. The results of analysis of the market established in the pharmaceutical market the presence of products of domestic producers with partial and full production cycle. Also the market presents preparations of manufacturers from Italy, Germany, Japan, Hungary and Ireland. It is established that the most active hyaluronic acid is used for the treatment of diseases of the musculoskeletal system. The analysis of literary sources showed that the most effective is the using of hyaluronic

APA, Harvard, Vancouver, ISO, and other styles

46

Lozama, Anthony. "Preparation of neoclerodane diterpenes as probes for the opioid receptor system." Diss., University of Iowa, 2010. https://ir.uiowa.edu/etd/703.

Full text

Abstract:

While there are a variety of therapeutics that interact with the opioid receptor system, they are not without side effects; including constipation, dysphoria and respiratory depression. A better understanding of the opioid receptor system may yield therapeutic agents with a limited side effect profile. The neoclerodane diterpene, salvinorin A, appears to interact at opioid receptors through a unique mode of action. A better understanding of its interactions with opioid receptors will yield valuable information about the opioid system. In order to probe further how salvinorin A interacts at opi

APA, Harvard, Vancouver, ISO, and other styles

47

Rigestam, Björn. "Pharmaceutical patents and generic drugs : When may interim injunctions be issued against an attempt or preparation to offer generic drugs on the market?" Thesis, Internationella Handelshögskolan, Högskolan i Jönköping, IHH, Rättsvetenskap, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-18933.

Full text

Abstract:

Since the implementation of Directive 2004/48 EC on the Enforcement of Intellectual Property Rights in Sweden there is today a possibility for pharmaceutical companies holding a patent to issue interim injunctions against a generic company on the grounds of an attempt or preparation to a pharmaceutical patent infringement. It has been shown that one of the earliest steps in which a generic company may infringe a pharmaceutical patent is to offer the generic drugs onto the market. However, since the implementation of the attempt and preparation rule in the Swedish Patent Act questions have been

APA, Harvard, Vancouver, ISO, and other styles

48

Sherwood, Alexander M. "Design, Synthesis and Biological Evaluation of Novel Compounds with CNS-Activity Targeting Cannabinoid and Biogenic Amine Receptors." ScholarWorks@UNO, 2014. http://scholarworks.uno.edu/td/1831.

Full text

Abstract:

This work seeks to contribute to the discipline of neuropharmacology by way of structure activity relationship from the standpoint of an organic chemist. More specifically, we sought to develop robust synthetic methodology able to efficiently produce an array of compounds for the purpose of systematic evaluation of their interaction with specific sights within the central nervous system (CNS) in order to better understand the mind and to develop drugs that may have beneficial effects on neurological function. The focus of these studies has been toward the development of novel molecules, using

APA, Harvard, Vancouver, ISO, and other styles

49

Parekh, Khushboo K. "Preparation, Characterization, and In Vitro Protein Release Studies in Pharmaceutically relevant Lecithin Microemulsions." University of Toledo Health Science Campus / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=mco1300753350.

Full text

APA, Harvard, Vancouver, ISO, and other styles

50

Serreqi, Alessio N. "Hydrolase catalyzed resolutions of enantiomers : a structural basis for the chiral preference of lipases : preparation of enantiomerically-pure phosphines, phospine oxides, sulfoxides and pipecolic acid." Thesis, McGill University, 1994. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=28918.

Full text

Abstract:

Enantiomerically-pure compounds are becoming increasingly important particularly to the pharmaceutical industry. Enzymes are useful tools in the synthesis of such compounds. To better understand how lipases discriminate between enantiomers of chiral secondary alcohols we obtained x-ray crystal structures of covalent complexes of Candida rugosa lipase with the transition-state analogs (1R)-menthyl hexylphosphonate and (1S)-menthyl hexylphosphonate. These compounds are transition-state analogs for the hydrolysis of menthyl esters. We observed that the transition-state analog of the unfavored (1S

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!