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Journal articles on the topic 'Pharmaceuticals preparations'

Author: Grafiati

Published: 28 May 2022

Last updated: 31 July 2025

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1

Abdul – Jabbar, Ruaa M., Batool M. Al-Adily, and Nuha F. Kadhim. "Ecotoxicological effects of pharmaceutical preparations and the possibility of removing them through phytoremediation: A review." Edelweiss Applied Science and Technology 8, no. 6 (2024): 2679–95. http://dx.doi.org/10.55214/25768484.v8i6.2531.

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From several decades, there was a significant increase in the production of pharmaceuticals due to their widespread use for both animal and human health. However, these pharmaceuticals also release large amounts of waste into the water environment, where they have been found at levels of ng/l to mg/l in wastewater and surface water. Additionally, because pharmaceuticals initially have biological effects such endocrine disruption, they may have a multitude of adverse effects. Hospitals are indicated or thought to be a significant and extremely variable source that is typically released into sew

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FISCHER, HOWARD. "Pedia-What!" Pediatrics 88, no. 4 (1991): 874. http://dx.doi.org/10.1542/peds.88.4.874.

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To the Editor.— Several pharmaceuticals manufactured for children have the prefix "pedia-" in their names. These include Pedicare (a line of cold and allergy preparations, McNeil), Pedialyte (oral electrolyte maintenance solution, Ross), Pediacof (a codeine-containing cough preparation, Winthrop Pharmaceuticals), PediaSure (liquid nutrition for children, Ross), Pediaflor (fluoride drops, Ross), Pediapred (prednisolone sodium phosphate, Fisons), and PediaProfen (Ibuprofen, McNeil). The first two on this list are sold without prescription. Although they are very different in appearance and thera

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3

Narotama, Indra, and Lathifah Hanim. "Investigation Action Against Children Who Are Circulating Pharmaceuticals Stocks That Does Not Have Permission In Jurisdictions Police Resort (Polres) Kudus." Jurnal Daulat Hukum 2, no. 1 (2019): 45. http://dx.doi.org/10.30659/jdh.v2i1.4205.

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This research to know the legal basis for investigation of cases of children who distribute pharmaceutical preparation which does not have a marketing authorization, the implementation of the investigation on the case of children who distribute pharmaceutical preparation which does not have a marketing authorization in the territory of the police station of the Kudus, barriers and solutions in the implementation of the investigation on the case of children who circulate preparations pharmacy that does not have a marketing authorization in the territory of the Kudus Police.The method used is em

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Gopiwad, Prachit. "Medicinal chemistry of catechol, a versatile pharmacophore." Current Trends in Pharmacy and Pharmaceutical Chemistry 6, no. 1 (2024): 7–11. http://dx.doi.org/10.18231/j.ctppc.2024.003.

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Catechol being a versatile pharmacophore, used in medicine as a molecular group in adjunction with other moieties and functional groups. The versatile pharmacophore has rendered several useful pharmaceuticals so far. The major medicines or the pharmaceutical drugs containing catechol moiety include levodopa, carbidopa, and several others. The FDA approved pharmaceutical preparations have been highlighted and reviewed in this paper.

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Saliy, О. О., M. E. Popova, H. V. Tarasenko, and V. S. Yarovenko. "Analysis and systematization of the main market trends development in pressurized pharmaceutical preparations in pharmaceutical and veterinary practice." Social Pharmacy in Health Care 8, no. 3 (2022): 60–70. http://dx.doi.org/10.24959/sphhcj.22.263.

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Aim. Analysis and systematization of the main market trends development in pressurized pharmaceutical preparations in pharmaceutical and veterinary practice. Materials and methods. Methods of systematic approach, bibliographic methods, information retrieval, analysis, comparison and generalization, statistical processing, tabular and graphic means of visual presentation of the obtained data were used during the market research. The analysis of registered in Ukraine pressurized pharmaceutical preparations was carried out based on the data of the State Register of Medicinal Products of Ukraine,

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Holovach, A. R., S. V. Kovalov, N. M. Deviatkina, V. M. Kovalov, D. V. Karamyshev, and V. O. Korshenko. "STANDARDIZATION OF RAW MATERIALS OF ERIGERON ANNUUS (ANNUAL FLEABANE)." Актуальні проблеми сучасної медицини: Вісник Української медичної стоматологічної академії 25, no. 1 (2025): 150–58. https://doi.org/10.31718/2077-1096.25.1.150.

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Medicinal plant raw materials and their derived preparations are widely used by leading pharmaceutical manufacturers and constitute a significant share of the global pharmaceutical market. Standardization plays a crucial role as a quality control mechanism for herbal medicinal products. The term “standardization’ refers to all measures taken during the production process and quality control to ensure the consistent quality of herbal preparations. To obtain high-quality herbal medicines, it is essential to oversee all stages of production, starting from proper cultivation and identification of

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7

Gunawardana SLA, Jayanika STC, Dabare PRL, and Siriwardhene MA. "Microbial contamination of selected nonsterile pharmaceuticals in OPD pharmacy of a teaching hospital in Sri Lanka." World Journal of Advanced Research and Reviews 13, no. 3 (2022): 295–303. http://dx.doi.org/10.30574/wjarr.2022.13.3.0189.

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A pharmaceutical product must be effective, safe and should be of good quality to assure their sustainability in the competitive pharmaceutical industry. The quality of the pharmaceutical products can be influenced by the presence of microorganisms (MO). In addition to sterile preparation contamination of non-sterile pharmaceuticals (NSP) should be monitored according to British Pharmacopeia (BP) microbial limits for the preparations. The objective of this study was to investigate the contamination of MOs of NSPs. Total 05 drug samples out of bulk opened containers were collected from OPD unit

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Gunawardana, SLA, STC Jayanika, PRL Dabare, and MA Siriwardhene. "Microbial contamination of selected nonsterile pharmaceuticals in OPD pharmacy of a teaching hospital in Sri Lanka." World Journal of Advanced Research and Reviews 13, no. 3 (2022): 295–303. https://doi.org/10.5281/zenodo.6413518.

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A pharmaceutical product must be effective, safe and should be of good quality to assure their sustainability in the competitive pharmaceutical industry. The quality of the pharmaceutical products can be influenced by the presence of microorganisms (MO). In addition to sterile preparation contamination of non-sterile pharmaceuticals (NSP) should be monitored according to British Pharmacopeia (BP) microbial limits for the preparations. The objective of this study was to investigate the contamination of MOs of NSPs. Total 05 drug samples out of bulk opened containers were collected from OPD unit

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9

Boguslavskyi, Ye P., H. L. Voskoboynikova, and A. M. Goy. "Analysis of trends in the positioning of pharmaceutical drugs of the SGLT-2 class of gliflozin derivatives at the pharmaceutical market and the application prospects." Social Pharmacy in Health Care 9, no. 1 (2023): 72–83. http://dx.doi.org/10.24959/sphhcj.23.282.

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Aim – is to analyze trends in the use and positioning of pharmaceuticals of the class of gliflozin derivatives on the Ukrainian pharmaceutical market. Materials and methods. In the conducted research, the methods of systematic and comparative analysis, generalization, statistical processing and synthesis were used in determining the projected perspectives, tabular and graphic means of presenting the results. To implement the goal and objectives of the research, software and electronic resources of ATX (Anatomical-Therapeutically-Chemical), ATC (Anatomical Therapeutically Chemical Classif

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10

Yang, Xinyi, and Fenxiao Chen. "Advances in Neural Networks for Pharmaceutical Applications." Asian Journal of Advanced Research and Reports 18, no. 1 (2024): 20–29. http://dx.doi.org/10.9734/ajarr/2024/v18i1595.

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Artificial neural networks (ANNs) are rapidly changing the landscape of the pharmaceutical industry. Their unique capabilities, including collective computing, adaptive learning, and fault tolerance, make them ideal for tackling complex challenges in drug discovery, analysis, and personalized medicine. This article summarizes the latest research progress in ANNs for pharmacy, highlighting breakthroughs in areas like QSAR modeling for drug design, pharmacokinetic prediction, and optimization of pharmaceutical preparations. With their immense potential to accelerate drug development, improve dru

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11

Espinosa-Mansilla, A., A. Muñoz Dela Peña, and F. Salinas. "Semiautomatic Determination of Furanic Aldehydes in Food and Pharmaceutical Samples by a Stopped-Flow Injection Analysis Method." Journal of AOAC INTERNATIONAL 76, no. 6 (1993): 1255–61. http://dx.doi.org/10.1093/jaoac/76.6.1255.

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Abstract A kinetic study of the reactions of 5-hydroxymethyl-2-furfuraldehyde and furfural with 2-thiobarbituric acid (TBA) by a stopped-flow flow injection analysis technique has been undertaken. A semiautomatic method for the analytical determination of these furanic aldehydes is proposed on the basis of reaction with TBA. The proposed stopped-flow method was successfully applied to several commercial pharmaceutical preparations and food samples. The procedure is faster than the earlier procedure for determination of these compounds in foods and pharmaceuticals.

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Pyka-Pająk, Alina. "New TLC Method Combined with Densitometry for Determination of Sertraline and Fluoxetine in Pharmaceutical Preparations." Processes 10, no. 10 (2022): 2083. http://dx.doi.org/10.3390/pr10102083.

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TLC combined with densitometry was used, and chromatographic conditions were developed to determination both fluoxetine and sertraline in pharmaceuticals. The mobile phase with the composition of acetone, chloroform, and ammonia (10:5:1, v/v) allowed separation of the most degradation products of sertraline and fluoxetine from all nineteen used in the study of mobile phases. Therefore, this mobile phase was selected as optimal for the analysis of sertraline and fluoxetine in pharmaceutical formulations. The RF values of sertraline and fluoxetine differ from the degradation products of fluoxeti

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Bhattacharjee, Meenakshi. "PHARMACEUTICALLY VALUABLE BIOACTIVE COMPOUNDS OF ALGAE." Asian Journal of Pharmaceutical and Clinical Research 9, no. 6 (2016): 43. http://dx.doi.org/10.22159/ajpcr.2016.v9i6.14507.

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ABSTRACT Pharmaceutically valuable products from micro algae and its industrial commercialization today is still in its infancy and can be seen as a gateway to a multibillion dollar industry. Microalgae generally grow autotrophically and are ubiquitous in nature.They represent a major untapped resource of genetic potential for valuable bioactive agents and fine biochemical. This proven ability of microalgae to produce these compounds places these microorganisms in the biotechnological spotlight for applications and commercialization as in the Pharmaceutical industry. The production of microalg

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14

Mohammad, Abu Sufian Md. Sahab Uddin* Md. Tanjir Islam Tahsin Zahan Kamal Hossain G. M. Sala Uddin Abdullah Al Mamun. "QUALITY CONTROL PARAMETERS OF PARENTERAL PHARMACEUTICALS BASED ON PHARMACOPOEIAS." iajps,csk publications 03, no. 12 (2017): 1624–38. https://doi.org/10.5281/zenodo.260129.

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Quality control is an essential operation of pharmaceutical industries. Drugs must be marketed as safe and therapeutically active formulations whose performance is consistent and predictable. New and better medicinal agents are being produced at an accelerated rate. At the same time more exacting and sophisticated analytical methods are being developed for their evaluation. Currently, world-wide efforts have been made to ensure the practice of quality along with coast effective good quality medicines. Parenterals are the sterile preparation that is directly administered into the circulatory sy

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15

Hegde, Aishwarya Laxmi, Archana B. Pagad, Anusha KR, and Anandhu KM. "Pharmaceutical Analytical Study of Laksha Rasa prepared in two distinct vessels: Emphasis on Ph variation following sequential filtration." Journal of Ayurveda and Integrated Medical Sciences 9, no. 12 (2025): 91–96. https://doi.org/10.21760/jaims.9.12.11.

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Primary preparations in Ayurvedic pharmaceuticals have certain Upakalpana under each. Preparations which share similar principles with its primary preparation can be considered as its Upakalpana. Laksha Rasa is an Upakalpana of Kwatha Kalpana. Laksha Rasa preparation was done in two different Dolayantra - a mud pot and a steel vessel. To one part of coarsely powdered Laksha tied in a Pottali and hung in a Dolayantra, six parts of water was added and heated on mild fire. It was reduced to 1/4th part and was filtered for 21 times. Organoleptic characters and physicochemical parameters were analy

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16

Annabi, Carrie Amani, and Suhayr Mustapha Wada. "Halal Pharmaceutical Industry in Nigeria: A bitter pill to swallow." Journal of Emerging Economies and Islamic Research 4, no. 2 (2016): 67. http://dx.doi.org/10.24191/jeeir.v4i2.9087.

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Notwithstanding Nigeria’s large Muslim population of 89.25 million citizens, very little research has been carried out in terms of addressing Halal needs in Nigeria. This qualitative case study reviewed the perspective of 32 respondents, (15 patients, 15 doctors and two pharmacists), in a medical centre in Abuja, Nigeria on their perceptions on and awareness of Halal pharmaceuticals. The interview data were collected through telephone interviews. Data analysis and findings were examined against the literature reviewed in this study. Findings concluded that there was a lack of awareness of Hala

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Annabi, Carrie Amani, and Suhayr Mustapha Wada. "Halal Pharmaceutical Industry in Nigeria: A bitter pill to swallow." Journal of Emerging Economies and Islamic Research 4, no. 2 (2016): 67–78. https://doi.org/10.24191/jeeir.v4i2.6372.

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Notwithstanding Nigeria’s large Muslim population of 89.25 million citizens, very little research has been carried out in terms of addressing Halal needs in Nigeria. This qualitative case study reviewed the perspective of 32 respondents, (15 patients, 15 doctors and two pharmacists), in a medical centre in Abuja, Nigeria on their perceptions on and awareness of Halal pharmaceuticals. The interview data were collected through telephone interviews. Data analysis and findings were examined against the literature reviewed in this study. Findings concluded that there was a lack of awareness of Hala

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18

Alcántara, Andrés R. "Biocatalysis and Pharmaceuticals: A Smart Tool for Sustainable Development." Catalysts 9, no. 10 (2019): 792. http://dx.doi.org/10.3390/catal9100792.

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Biocatalysis is the term used to describe the application of any type of biocatalyst (enzymes, as isolated preparations of wild-type or genetically modified variants, or whole cells, either as native cells or as recombinant expressed proteins inside host cells) in a given synthetic schedule [...]

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19

Fernández, J. M. López, M. D. Luque de Castro, and M. Valcárcel. "Automatic continuous on-line monitoring of salicylic acid and acetylsalicylic acid in pharmaceuticals." Journal of Automatic Chemistry 12, no. 6 (1990): 263–66. http://dx.doi.org/10.1155/s1463924690000335.

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An asymmetrical FIA merging-zones manifold based on the dual injection of two sample microvolumes was developed for the simultaneous determination of salicylic acid and acetylsalicylic acid in pharmaceutical preparations at a sampling frequency of 30/h. The complex formed between the Fe(III) reagent continuously introduced in the system and salicylic acid was monitored photometrically at 520 nm. One of the sample plugs was prehydrolysed on injection into an NaOH stream and was circulated through a longer channel than the other plug. This yielded two FIA peaks corresponding to salicylic acid an

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Gomes Carpes, Camila, Caroline Venturi, and Martin Steppe. "Quality evaluation of solid pharmaceutical preparations for veterinary use containing cephalexin." Drug Analytical Research 6, no. 2 (2023): 18–22. http://dx.doi.org/10.22456/2527-2616.128550.

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The analysis of pharmaceuticals is fundamental in both human and veterinary medicine. In this context, quality control must accompany the process from the acquisition of raw material to the transformation into a finished product, since its goal is to ensure safe and effective drugs for human or animal consumption. Considering the significant increase in veterinary prescriptions containing antimicrobial drugs, the present work carried out a search for information about the qualification of veterinary preparations available in the national market, highlighting, through legislation, the quality p

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Vasilica, RUSU. "ASSESSMENT OF UNCERTAINTY WHILE SELECTING THE OPERATIONAL STRATEGY BY THE INDUSTRIAL ENTERPRISES IN ROMANIA." ECONOMY AND SOCIOLOGY 2019 NO. 1, no. 2021.1 (July 1, 2021): 75–86. http://dx.doi.org/10.36004/nier.es.2021.1-07.

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In conditions of uncertainty, an enterprise should have a rational basis for making decisions, which would enable the comparison of different alternatives and the choice of the most suitable action for achieving its objectives. Some researchers consider that uncertainty is generated either by insufficient knowledge about the nature of phenomena and processes or by the lack of information about these phenomena and processes. The author considers that these interpretations need to be completed by clarifying the motives which cause uncertainty. The following types of environment can be distinguis

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Olabiyi, Ayodeji A., and Lisandra E. de Castro Brás. "Cardiovascular Remodeling Post-Ischemia: Herbs, Diet, and Drug Interventions." Biomedicines 11, no. 6 (2023): 1697. http://dx.doi.org/10.3390/biomedicines11061697.

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Cardiovascular disease (CVD) is a serious health burden with increasing prevalence, and CVD continues to be the principal global source of illness and mortality. For several disorders, including CVD, the use of dietary and medicinal herbs instead of pharmaceutical drugs continues to be an alternate therapy strategy. Despite the prevalent use of synthetic pharmaceutical medications, there is currently an unprecedented push for the use of diet and herbal preparations in contemporary medical systems. This urge is fueled by a number of factors, the two most important being the common perception th

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Vanda, Marković Peković. "PRODUCTION OF PHARMACEUTICAL AND COSMETIC PREPARATIONS IN PHARMACIES IN BOSNIA AND HERZEGOVINA IN THE AUSTRO-HUNGARIAN PERIOD." ACTA HISTORIAE MEDICINAE stomatologiae, pharmacie, medicinae veterinae 39, no. 1-2 (2021): 56–70. https://doi.org/10.5281/zenodo.4589438.

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In the Austro-Hungarian period (1878-1918) in Bosnia and Herzegovina (BIH) an increasing number of modern pharmacies began to open. According to the regulations passed in 1878 and 1907, which regulated the pharmacy activity, the owner of a pharmacy could only be a Doctor of Chemistry or a Master of Pharmacy with a degree from an Austro-Hungarian university. Only a Master of Pharmacy or an assistant with an appropriate diploma would be able to prepare and dispense medications, in accordance with the current pharmacopoeia and list prices. Advertisements for various medications and preparations,

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Krzek, Jan, and Magorzata Starek. "Simultaneous Densitometric Determination of Indomethacin and Its Degradation Products, 4-Chlorobenzoic Acid and 5-Methoxy-2-Methyl-3-Indoleacetic Acid, in Pharmaceutical Preparations." Journal of AOAC INTERNATIONAL 84, no. 6 (2001): 1703–7. http://dx.doi.org/10.1093/jaoac/84.6.1703.

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Abstract A densitometric method was developed for the identification and determination of indomethacin and its degradation products, 4-chlorobenzoic acid and 5-methoxy-2-methyl-3-indoleacetic acid, in pharmaceuticals. To separate these compounds, silica gel-coated thin-layer chromatography plates and the following mobile phase were used: 2-propanol–25% ammonia–water (8 + 1 + 1, v/v). UV densitometric measurements were made by comparing the absorption spectra and Rf values of appropriate standards with the pharmaceutical preparations examined. The conditions for separation were established and

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Nurani, Laela Hayu, Citra Ariani Edityaningrum, Irnawati Irnawati, et al. "Chemometrics-Assisted UV-Vis Spectrophotometry for Quality Control of Pharmaceuticals: A Review." Indonesian Journal of Chemistry 23, no. 2 (2023): 542. http://dx.doi.org/10.22146/ijc.74329.

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Spectroscopic method in the UV-Vis region is considered the most molecular spectrometric method for content determination of a single component. However, a lot of pharmaceutical dosage forms comprise two or more components which lead to peak overlapping. Moreover, in the chemical stability test, active pharmaceutical ingredient (API) was also found along with the degradation products, impurities, and adulterant compounds. UV-Vis spectroscopy is one of the methods of choice for the determination or quantification of a single component in pharmaceutical preparations. The pharmaceutical products

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Ali, Abbas Fadhil, Mustafa Aziz Rahi, Kamil K. Atiyah Altameemi, Mohammed Kassim Al-hussainawy, and Munthir Abdulwahid Abdulhussain. "Spectrophotometric Assessment of Pyrocatechol Drug Employing Oxidative Coupling Reaction with 4-amino antipyrine as a Model of Pharmaceutical Compounds ." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 14, no. 03 (2024): 1384–88. http://dx.doi.org/10.25258/ijddt.14.3.19.

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A rapid, simple, sensitive, and higher stability spectrophotometric method was developed the determine that it is stable Pyrocatechol drug in pure and pharmaceutical preparations. The method is based on an oxidative coupling reaction among Pyrocatechol drug and 4-amino antipyrine (4AAP) in the presence of potassium iodate (KIO3) in an acid medium to form a color complex that stable violet dye and a maximum absorption at 505 nm. The best optimum conditions and other analytical factors have been evaluated. A calibration curve of absorbance of several concentrations that obey the law of Beer-Lamb

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Pakhomovich, Sergey, Oksana Chepinoga, and Mikhail Solodkov. "On the Issue of the Development of Import Substitution in the Pharmaceutical Industry." Bulletin of Baikal State University 34, no. 2 (2024): 379–88. https://doi.org/10.17150/2500-2759.2024.34(2).379-388.

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Currently, a combination of unfavorable external conditions makes the problem of developing import substitution in many industries, one of which is pharmaceuticals, particularly relevant for the Russian economy. The production of medicines is not only one of the most socially significant industries, but also represents an essential component of the state’s economic security system. The article examines the current state of the pharmaceutical industry in Russia and the reasons for the continued high share of imported drugs in the domestic market. Features of the functioning of the industry and

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Derda, Monika, and Edward Hadaś. "The use of phytotherapy in diseases caused by parasitic protozoa." Acta Parasitologica 60, no. 1 (2014): 1–8. http://dx.doi.org/10.1515/ap-2015-0001.

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AbstractThe paper presents an overview of the use of natural therapeutic agents in combating parasitic diseases. Nowadays there is increasing demand for proven plant therapies, which often are found to be more effective than synthetic pharmaceuticals in chronic diseases. In many cases herbal preparations perfectly supplement the conventional treatment and at the same time do not cause side effects. On the pharmaceutical market there are many drugs of plant origin which have been applied in the treatment of parasitic diseases. However, researchers are still looking for new plants, or specific s

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Dedov, I. I., G. A. Mel'nichenko, Zh E. Belaia, and L. Ia Rozhinskaia. "Osteoporosis: from a rare symptom of endocrine diseases to the tacit epidemic of XX-XXI centuries." Problems of Endocrinology 57, no. 1 (2011): 35–45. http://dx.doi.org/10.14341/probl201157135-45.

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This article describes the history of knowledge management with special reference to primary and secondary osteoporosis, its epidemiology and diagnostics of different forms of this disease. The discussion is focused on therapeutic modalities for the treatment of osteoporosis based on the principles of evidence-based medicine. Special attention is given to the choice of optimal medicinal preparations for the management of primary osteoporosis taking into account results of multicenter randomized placebo-controlled clinical studies and the results of evaluation of the efficacy of various pharmac

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Muhammad, Muhammad Jassim, Awatif I. Muhammed, and Haneen Muhammad Jassim. "Formulation of Neomycin Sulphate 0.35 %(w/v) & Hydrocortisone 0.5% Otic Drop." Iraqi Journal of Industrial Research 9, no. 1 (2022): 115–19. http://dx.doi.org/10.53523/ijoirvol9i1id154.

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Neomycin sulfate and hydrocortisone ear drops of veterinary pharmaceuticals used as an antibiotic and ant inflammatory to treat infections caused by bacterial infections in the middle ear of large and small field animals caused by gram positive and negative bacteria like, Staphylococcus aureus, Escherichia coli, Homophiles influenza, Klebsiella–Enterobacter species, Neisseria species, and Pseudomonas aeruginosa. The action of mechanism neomycin sulfate is inhibition of protein synthesis in bacteria cell which is lead to kill the bacteria and the action of hydrocortisone is ant inflammation in

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Holt, Robert J., Scott W. K. Siegert, and Aravind Krishna. "Physical Compatibility of Ibuprofen Lysine Injection with Selected Drugs During Simulated Y-site Injection." Journal of Pediatric Pharmacology and Therapeutics 13, no. 3 (2008): 156–61. http://dx.doi.org/10.5863/1551-6776-13.3.156.

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PURPOSE To study the physical compatibility of ibuprofen lysine injection (NeoProfen, Ovation Pharmaceuticals Inc., Deerfield, IL) with medications commonly used in the premature neonatal population during simulated Y-site administration. MATERIALS AND METHODS Commonly used intravenous medications in preterm infants were evaluated for physical compatibility with ibuprofen lysine injection. A 20-mL sample of ibuprofen lysine drug product solution was mixed with a 20-mL sample of each of the 34 medications at concentrations used clinically. The mixtures were stored at room temperature and each s

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Ribeiro, Paulo Roberto Da Silva, Leonardo Pezza, and Helena Redigolo Pezza. "A SIMPLE SPECTROPHOTOMETRIC METHOD FOR THE DETERMINATION OF CAPTOPRIL IN PHARMACEUTICAL PREPARATIONS USING AMMONIUM MOLYBDATE." Eclética Química Journal 35, no. 3 (2018): 179. http://dx.doi.org/10.26850/1678-4618eqj.v35.3.2010.p179-188.

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A simple, rapid and sensitive spectrophotometric method for the determination of captopril (CPT) in pharmaceutical formulations is proposed. This method is based on the reduction reaction of ammonium molybdate, in the presence of sulphuric acid, for the group thiol of CPT, producing a green compound (λmax 407 nm). Beer’s law is obeyed in a concentration range of 4.60 x 10-4 – 1.84 x 10-3 mol l-1 of CPT with an excellent correlation coefficient (r = 0.9995). The limit of detection and limit of quantification were 7.31 x 10-6 e 2.43 x 10-5 mol l-1 of CPT, respectively. The proposed method was su

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Ribeiro, P. R. S., L. Pezza, and H. R. Pezza. "A simple spectrophotometric method for the determination of captopril in pharmaceutical preparations using ammonium molybdate." Eclética Química 35, no. 3 (2010): 179–88. http://dx.doi.org/10.1590/s0100-46702010000300018.

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A simple, rapid and sensitive spectrophotometric method for the determination of captopril (CPT) in pharmaceutical formulations is proposed. This method is based on the reduction reaction of ammonium molybdate, in the presence of sulphuric acid, for the group thiol of CPT, producing a green compound (λ max 407 nm). Beer's law is obeyed in a concentration range of 4.60 x 10-4 - 1.84 x 10-3 mol l-1 of CPT with an excellent correlation coefficient (r = 0.9995). The limit of detection and limit of quantification were 7.31 x 10-6 e 2.43 x 10-5 mol l-1 of CPT, respectively. The proposed method was s

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Kepekci Tekkeli, Serife Evrim. "Development of an HPLC-UV Method for the Analysis of Drugs Used for Combined Hypertension Therapy in Pharmaceutical Preparations and Human Plasma." Journal of Analytical Methods in Chemistry 2013 (2013): 1–10. http://dx.doi.org/10.1155/2013/179627.

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A simple, rapid, and selective HPLC-UV method was developed for the determination of antihypertensive drug substances: amlodipine besilat (AML), olmesartan medoxomil (OLM), valsartan (VAL), and hydrochlorothiazide (HCT) in pharmaceuticals and plasma. These substances are mostly used as combinations. The combinations are found in various forms, especially in current pharmaceuticals as threesome components: OLM, AML, and HCT (combinationI) and AML, VAL, and HCT (combinationII). The separation was achieved by using an RP-CN column, and acetonitrile-methanol-10 mmol orthophosphoric acid pH 2.5 (7

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LÖWY, ILANA. "‘Sexual chemistry’ before the Pill: science, industry and chemical contraceptives, 1920–1960." British Journal for the History of Science 44, no. 2 (2010): 245–74. http://dx.doi.org/10.1017/s0007087410000762.

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AbstractThe history of contraceptives met the history of drugs long before the invention of the contraceptive pill. In the first half of the twentieth century, numerous pharmaceutical laboratories, including major ones, manufactured and marketed chemical contraceptives: jellies, suppositories, creams, powders and foams applied locally to prevent conception. Efforts to put an end to the marginal status of these products and to transform them into ‘ethical’ drugs played an important role in the development of standardized laboratory tests of efficacy of contraceptive preparations; debates on the

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El-Brashy, A., M. Eid, and W. Talaat. "Kinetic Spectrophotometric Method For The Determination of Ketoprofen in Pharmaceuticals and Biological Fluids." International Journal of Biomedical Science 2, no. 4 (2006): 405–12. http://dx.doi.org/10.59566/ijbs.2006.2405.

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A simple and sensitive kinetic method is described for the determination of ketoprofen in pure form, pharmaceuticals and biological fluids. The method utilizes an oxidative- coupling reaction based upon oxidation of 3-methyl-2-benzo-thiazolinone hydrazone hydrochloride (MBTH) with Ce(IV) in presence of HCl, where an electrophilic intermediate (diazonium salt of the reagent) is produced, then couples with ketoprofen yielding a highly colored condensation product. The absorbance is measured after 20 min at 605 nm. Calibration graph was linear over the concentration range of 1-8 µg/mL with a mini

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Gagliardi, L., G. Multari, G. Cavazzutti, D. De Orsi, and D. Tonelli. "HPLC Determination of Ciclopirox, Octopirox, and Pyrithiones in Pharmaceuticals and Antidandruff Preparations." Journal of Liquid Chromatography & Related Technologies 21, no. 15 (1998): 2365–73. http://dx.doi.org/10.1080/10826079808000544.

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Basavaiah, Kanakapura, Hullikal Prameela, and Bankavadi Somashekar. "Spectrophotometric determination of pefloxacin mesylate in pharmaceuticals." Acta Pharmaceutica 57, no. 2 (2007): 221–30. http://dx.doi.org/10.2478/v10007-007-0018-4.

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Spectrophotometric determination of pefloxacin mesylate in pharmaceuticalsA spectrophotometric method is described for assay of pefloxacin mesylate (PFM) in bulk drug and in tablets. The method is based on back extraction of the bromophenol blue dye at pH 5.2 from the dye-drug ion pair followed by measurement of the dye absorbance at 590 nm. The working conditions of the method were investigated and optimized. Beer's law plot showed a good correlation in the concentration range of 0.15-1.25 μg mL-1.Sensitivity indices such as molar absorptivity, limits of detection and quantification are repor

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Bharatia, Rakesh, Nidhi Gupta, Preeti Upadhyay, and Shailendra Kumar. "Review on "Herbal Preparations from Ayurveda used to treat Rheumatoid Arthritis"." International Journal of Pharma Professional’s Research (IJPPR) 15, no. 1 (2024): 167–72. http://dx.doi.org/10.48165/ijppronline.2024.15113.

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Ayurveda is a natural medicine system that originated in India over 3,000 years ago. The name "Ayurveda" (science or knowledge) is derived from the Sanskrit words Ayur (life) and Veda. Thus, the name Ayurveda, which means "knowledge of life." The popularity of Ayurveda, or traditional. Since most patients begin taking conventional medications as soon as they are diagnosed, ayurvedic therapies are usually administered in combination with or after orthodox medical techniques. To properly grasp the potential effect of food, spices, and medicinal plants, one must have a thorough understanding of t

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Basavaiah, Kanakapura, Urdigere Kumar, and Kalsang Tharpa. "Bromatomatric assay of gatifloxacin in pharmaceuticals." Chemical Industry and Chemical Engineering Quarterly 14, no. 3 (2008): 185–90. http://dx.doi.org/10.2298/ciceq0803185b.

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Three new, simple, and cost-effective visible spectrophotometric methods are proposed for determination of gatifloxacin (GTF) using bromate-bromide mixture, and three dyes, methyl orange, indigocarmine and thymol blue, as reagents. The methods engross the addition of a known excess of bromate-bromide mixture to GTF in hydrochloric acid medium followed by determination of residual bromine by reacting with a fixed amount of either methyl orange and measuring the absorbance at 520 nm (method A) or indigo carmine and measuring the absorbance at 610 nm (method B) or thymol blue and measuring the ab

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Tsekouras, Vasileios, and Spyridon Kintzios. "Biotechnology of Viscum Album L. and Cancer Treatment: A Review." Current Bioactive Compounds 16, no. 6 (2020): 738–46. http://dx.doi.org/10.2174/1573407215666190410151958.

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Background: This review aims to highlight biotechnological techniques applied for the identification, isolation and propagation of mistletoe-derived bioactive compounds and the preclinical evaluation of their anticancer properties. Methods: We undertook a structured search of bibliographic databases to identify and evaluate the literature, regarding biotechnology of mistletoe and malignancy treatment. The selected articles were classified into five modules according to the study design. Results: Firstly, we have provided an overview of the role of biotechnology in plant-derived pharmaceuticals

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Codevilla, Cristiane Franco, Tamara dos Santos Castilhos, and Ana Maria Bergold. "A review of analytical methods for the determination of four new phosphodiesterase type 5 inhibitors in biological samples and pharmaceutical preparations." Brazilian Journal of Pharmaceutical Sciences 49, no. 1 (2013): 1–11. http://dx.doi.org/10.1590/s1984-82502013000100002.

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The introduction of oral phosphodiesterase type 5 inhibitor therapy in 1998 revolutionized the treatment of erectile dysfunction. Erectile dysfunction is the most common sexual problem in men. It often has a profound effect on intimate relationships and quality of life. The analysis of pharmaceuticals is an important part of the drug development process as well as for routine analysis and quality control of commercial formulations. Whereas the determination of sildenafil citrate, vardenafil and tadalafil are well documented by a variety of methods, there are few publications about the determin

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Zhang, Dandan, Weijian Wang, Haiyun Zhao, et al. "Structural Identification of Impurities in Pioglitazone Hydrochloride Preparations by 2D-UHPLC-Q-Exactive Orbitrap HRMS and Their Toxicity Prediction." International Journal of Analytical Chemistry 2023 (October 17, 2023): 1–12. http://dx.doi.org/10.1155/2023/2096521.

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Pharmaceutical companies and regulatory agencies have more and more concerns for impurities in pharmaceuticals and their toxicity. In this work, heart-cutting two-dimensional ultrahigh-performance liquid chromatography (2D-UHPLC) in combination with high-resolution mass spectrometry (HRMS) was used, setting HRMS as positive mode of electrospray ionization to identify five impurities in pioglitazone hydrochloride preparations. With the heart-cutting 2D-UHPLC and online desalting technique, the structures of five impurities were deduced in an analysis of MSn data. And three of them, Impurity-2,

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Reznikov, Konstantin, Narine Gorbunova, Pavel Kolesnichenko, et al. "SEARCH OF NEW PHARMACEUTICALS ON THE BASIS OF DARBEPOETIN IN THE TREATMENT OF ISCHEMIC STROKE (REVIEW OF LITERATURE)." Research Results in Pharmacology 3, no. (1) (2017): 125–36. https://doi.org/10.18413/2500-235X-2017-3-1-125-136.

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The article contains the analysis of medical and biological publications from the global database created by the National Centre for Biology Information (NCBI), an intramural biotechnological division of the US National Library of Medicine. The authors have analyzed publications of the recent ten years. Major results of study of erythropoietins and their recombinant analogues have been generalized and systematized. There has been revealed the significant potential of the preparations of this group to be studied and used. Major advantages and drawbacks of erythropoietins and their recombinant a

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Gergovska, Malena, Kristina Semkova, Jana Kazandjieva, and Nikolay Tsankov. "Perianal Allergic Contact Dermatitis from Benzocaine – a Case Report." Serbian Journal of Dermatology and Venerology 5, no. 4 (2013): 183–87. http://dx.doi.org/10.2478/sjdv-2013-0016.

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Abstract A large number of contact allergic reactions to benzocaine have been reported since its introduction to the pharmaceutical market as an active ingredient in different over-the-counter anesthetic ointments. Benzocaine is used as a key ingredient in many pharmaceuticals, such as products for oral ulcers, wound and burn preparations, sunburn remedies, hemorrhoidal preparations, oral and gingival products, sore throat sprays/lozenges, callous and wart remedies, creams for treatment of poison ivy dermatitis, tooth ache and denture irritation products. We present a 56-year-old Caucasian mal

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I., C. Shukla, Kumar Vinod, and K. Singh Brijesh. "Application of ammonium hexanitratocerate(IV) for the determination of some antibiotics." Journal of Indian Chemical Society Vol. 88, Sep 2011 (2011): 1383–88. https://doi.org/10.5281/zenodo.5787917.

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Department of Chemistry, University of Allahabad, Allahabad-211 002, Uttar Pradesh, India <em>E-mail</em> : prof.icshukla@rediffmail.com <em>Manuscript received 15 September 2010, revised 22 February 2011, accepted 25 February 2011</em> A simple and convenient method has been developed for milligram determination of some Antibiotic drugs e.g. Amoxicillin sodium, Ampicillin, Cefixime, Cloxacillin sodium, Norfloxacin and Ornidazole in pure form and in their pharmaceutical preparations. The method involves the oxidation of compounds with 0.1 M ammonium hexanitratocerate(IV) reagent in acidic medi

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Orazymbetova, N., M. Seisenbaeva, A. Zhakypbek, Zh Koshemetov, B. Umuraliyev, and A. Isakhan. "CONTROL OF SOME PARAMETERS OF THE ANTHRAX VACCINE FOR CATTLE AND SMALL RUMINANT." Biosafety and Biotechnology, no. 21 (April 2, 2025): 15–23. https://doi.org/10.58318/2957-5702-2025-21-15-23.

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Testing of biological products for sterility, harmlessness and determination of the concentration of hydrogen ions is mandatory in the pharmaceutical industry and is regulated by pharmacopoeias. Pharmaceuticals intended for intravenous, subcutaneous and intramuscular administration, as well as some other solutions, are available marked "sterile", therefore they must be checked at production. The ingress of microflora into sterile preparations can cause an inflammatory process or a septic condition, therefore the manufacturer is fully responsible for the sterility and harmlessness of solutions

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Ali Esmail Al-Snafi. "Hypotensive and vascular activities of medicinal plants." GSC Biological and Pharmaceutical Sciences 19, no. 3 (2022): 044–63. http://dx.doi.org/10.30574/gscbps.2022.19.3.0214.

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Plants are a valuable source of a wide range of secondary metabolites, which are used as pharmaceuticals preparations. The previous studied showed that many medicinal plants possessed hypotensive effects and affected vascular activity either by direct effect on vascular smooth muscles or indirectly by affecting endothelium vasoactive substances. The current review was designed to highlight the medicinal plants with hypotensive and vascular effects as promising future therapies because of efficacy and safety.

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Ali, Esmail Al-Snafi. "Hypotensive and vascular activities of medicinal plants." GSC Biological and Pharmaceutical Sciences 19, no. 3 (2022): 044–63. https://doi.org/10.5281/zenodo.6840763.

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Plants are a valuable source of a wide range of secondary metabolites, which are used as pharmaceuticals preparations. The previous studied showed that many medicinal plants possessed hypotensive effects and affected vascular activity either by direct effect on vascular smooth muscles or indirectly by affecting endothelium vasoactive substances. The current review was designed to highlight the medicinal plants with hypotensive and vascular effects as promising future therapies because of efficacy and safety.

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Putri Meisa Anggesta, Heldi Candra, and Fifin Oktaviani. "Management Evaluation of Expired and Slow-Moving Medications at Hospital X in Batam City." Open Access Indonesian Journal of Medical Reviews 4, no. 1 (2024): 566–68. http://dx.doi.org/10.37275/oaijmr.v4i1.504.

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Efficient drug management necessitates a well-structured supply chain to ensure the smooth functioning of health services. The objective of this study is to ascertain the strategies employed for the disposal of expired medications and the handling of slow-moving pharmaceuticals at Hospital X in Batam City. This research is characterized as descriptive-observational, employing a retrospective methodology. Data analysis involves doing qualitative analysis to assess the degree of rationality, followed by quantitative analysis using a formula. The findings of this study indicate that the highest p

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