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Relevant bibliographies by topics / Phloroglucinol compound

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Academic literature on the topic 'Phloroglucinol compound'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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Journal articles on the topic "Phloroglucinol compound"

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Bare, Yohanes. "Interaction Phloroglucinol as inflammation therapy through Cyclooxygenase-2 (COX-2) gene inhibition." Jurnal Ilmiah Medicamento 8, no. 1 (2022): 14–21. http://dx.doi.org/10.36733/medicamento.v8i1.3162.

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Exploration of natural compounds is one of the projects in the context of curving disease, one of which is inflammatory therapy in the body, one of the natural ingredients used is Phloroglucinol which has anti-inflammatory properties but there is no information on molecular studies related to its activity. The purpose of this study was to explore the potential of Phloroglucinol as an anti-inflammatory mechanism. Phloroglucinol compound (CID 359) was downloaded from the PubChem Protein COX-2 database (PDB ID 6cox) downloaded from the Protein Data Bank database. The compound Phloroglucinol inter

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Catarino, Marcelo D., Beatriz S. Baía Costa, Ana Rita Circuncisão, Artur M. S. Silva, Susana M. Cardoso та Susana Santos Braga. "γ-Cyclodextrin Inclusion of Phloroglucinol: Solid State Studies and Antioxidant Activity throughout the Digestive Tract". Applied Sciences 12, № 5 (2022): 2340. http://dx.doi.org/10.3390/app12052340.

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Phloroglucinol is a powerful antioxidant compound and an active pharmaceutical ingredient used in the management of intestinal spasms. In this report, we describe the interaction of γ-cyclodextrin with phloroglucinol to readily form a solid inclusion compound with 1:1 by co-dissolution and freeze-drying. Solid-state characterisation using FT-IR, thermal analyses (TGA and DTA) and X-ray powder diffraction confirmed the formation of a true inclusion compound (γ-CD·PG) in which the molecules of γ-CD are stacked into channels. This spatial arrangement is typical of γ-CD inclusion compounds, and it

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Teng, Xingxing, Yuanyuan Wang, Jinhua Gu, Peiqi Shi, Zhibin Shen, and Lianbao Ye. "Antifungal Agents: Design, Synthesis, Antifungal Activity and Molecular Docking of Phloroglucinol Derivatives." Molecules 23, no. 12 (2018): 3116. http://dx.doi.org/10.3390/molecules23123116.

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Pseudoaspidinol is a phloroglucinol derivative with Antifungal activity and is a major active component of Dryopteris fragrans. In our previous work, we studied the total synthesis of pseudoaspidinol belonging to a phloroglucinol derivative and investigated its antifungal activity as well as its intermediates. However, the results showed these compounds have low antifungal activity. In this study, in order to increase antifungal activities of phloroglucinol derivatives, we introduced antifungal pharmacophore allylamine into the methylphloroglucinol. Meanwhile, we remained C1–C4 acyl group in C

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Park, Cheol, Hee-Jae Cha, Hyun Hwangbo, et al. "Phloroglucinol Inhibits Oxidative-Stress-Induced Cytotoxicity in C2C12 Murine Myoblasts through Nrf-2-Mediated Activation of HO-1." International Journal of Molecular Sciences 24, no. 5 (2023): 4637. http://dx.doi.org/10.3390/ijms24054637.

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Phloroglucinol is a class of polyphenolic compounds containing aromatic phenyl rings and is known to have various pharmacological activities. Recently, we reported that this compound isolated from Ecklonia cava, a brown alga belonging to the family Laminariaceae, has potent antioxidant activity in human dermal keratinocytes. In this study, we evaluated whether phloroglucinol could protect against hydrogen peroxide (H2O2)-induced oxidative damage in murine-derived C2C12 myoblasts. Our results revealed that phloroglucinol suppressed H2O2-induced cytotoxicity and DNA damage while blocking the pro

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Li, Ning, Shabana Khan, Shi Qiu, and Xing-Cong Li. "Synthesis and Anti-Inflammatory Activities of Phloroglucinol-Based Derivatives." Molecules 23, no. 12 (2018): 3232. http://dx.doi.org/10.3390/molecules23123232.

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The natural product phloroglucinol-based derivatives representing monoacyl-, diacyl-, dimeric acyl-, alkylated monoacyl-, and the nitrogen-containing alkylated monoacylphloro- glucinols were synthesized and evaluated for inhibitory activities against the inflammatory mediators such as inducible nitric oxide synthase (iNOS) and nuclear factor kappaB (NF-κB). The diacylphloroglucinol compound 2 and the alkylated acylphloroglucinol compound 4 inhibited iNOS with IC50 values of 19.0 and 19.5 µM, respectively, and NF-κB with IC50 values of 34.0 and 37.5 µM, respectively. These compounds may serve a

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Paumann-Page, Martina, Christian Obinger, Christine C. Winterbourn, and Paul G. Furtmüller. "Peroxidasin Inhibition by Phloroglucinol and Other Peroxidase Inhibitors." Antioxidants 13, no. 1 (2023): 23. http://dx.doi.org/10.3390/antiox13010023.

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Human peroxidasin (PXDN) is a ubiquitous peroxidase enzyme expressed in most tissues in the body. PXDN represents an interesting therapeutic target for inhibition, as it plays a role in numerous pathologies, including cardiovascular disease, cancer and fibrosis. Like other peroxidases, PXDN generates hypohalous acids and free radical species, thereby facilitating oxidative modifications of numerous biomolecules. We have studied the inhibition of PXDN halogenation and peroxidase activity by phloroglucinol and 14 other peroxidase inhibitors. Although a number of compounds on their own potently i

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Alexanyan, Karina G., Olga A. Stokolos, Samir Yu Salmanov, et al. "SYNTHESIS AND STUDY OF PROPERTIES OF DERIVATIVES OF PHLOROGLUCINOLMETHYLVIOLOGEN AS ANTIOXIDANT ADDITIVES TO OILS." IZVESTIYA VYSSHIKH UCHEBNYKH ZAVEDENII KHIMIYA KHIMICHESKAYA TEKHNOLOGIYA 62, no. 8 (2019): 132–38. http://dx.doi.org/10.6060/ivkkt.20196208.5993.

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At the present time there is a need to search for new organic compounds with pronounced antioxidant activity. In this work, we studied indicators of antioxidant stability of the compounds obtained by the modification of the phloroglucinol and methylviologen, and identified the basic principles of the synthesis of antioxidant additives. Moreover, the synthesized compounds can act as metal deactivator. These deactivators are phenolic compounds containing functional groups, for example, the iminogroup, which lead to the deactivation of the metal ion through the formation of stable complexes. A li

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Park, Cheol, Hee-Jae Cha, Min Yeong Kim, et al. "Phloroglucinol Attenuates DNA Damage and Apoptosis Induced by Oxidative Stress in Human Retinal Pigment Epithelium ARPE-19 Cells by Blocking the Production of Mitochondrial ROS." Antioxidants 11, no. 12 (2022): 2353. http://dx.doi.org/10.3390/antiox11122353.

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Phloroglucinol, a phenolic compound, is known to possess a potent antioxidant ability. However, its role in retinal cells susceptible to oxidative stress has not been well elucidated yet. Thus, the objective of this study was to evaluate whether phloroglucinol could protect against oxidative damage in cultured human retinal pigment epithelium ARPE-19 cells. For this purpose, ARPE-19 cells were stimula ted with hydrogen peroxide (H2O2) to mimic oxidative stress. Cell viability, cytotoxicity, apoptosis, reactive oxygen species (ROS) generation, mitochondrial function, DNA damage, and autophagy w

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Abdulrashid, Nasirudeen Idowu, Suleiman Aminu, Rahma Muhammad Adamu, et al. "Phloroglucinol as a Potential Candidate against Trypanosoma congolense Infection: Insights from In Vivo, In Vitro, Molecular Docking and Molecular Dynamic Simulation Analyses." Molecules 27, no. 2 (2022): 469. http://dx.doi.org/10.3390/molecules27020469.

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Sub-Saharan Africa is profoundly challenged with African Animal Trypanosomiasis and the available trypanocides are faced with drawbacks, necessitating the search for novel agents. Herein, the chemotherapeutic potential of phloroglucinol on T. congolense infection and its inhibitory effects on the partially purified T. congolense sialidase and phospholipase A2 (PLA2) were investigated. Treatment with phloroglucinol for 14 days significantly (p < 0.05) suppressed T. congolense proliferation, increased animal survival and ameliorated anemia induced by the parasite. Using biochemical and histop

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Kurnia, Dikdik, Dadan Sumiarsa, Hendra D. A. Dharsono, and Mieke H. Satari. "Bioactive Compounds Isolated from Indonesian Epiphytic Plant of Sarang Semut and Their Antibacterial Activity against Pathogenic Oral Bacteria." Natural Product Communications 12, no. 8 (2017): 1934578X1701200. http://dx.doi.org/10.1177/1934578x1701200814.

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A new phenolic compound (1), a steroid (2), a new steroid glycoside (4), two triterpenoids (3 & 6) and a new phloroglucinol-sesquiterpene (5) have been isolated from the ethyl acetate extract of Sarang Semut ( Myrmecodia pendans) and their structures were determined on the basis of the spectral data. The bioactivity evaluation was conducted with the inhibition zone of compounds (mm) using Kirby-Bauer method at concentrations of 1000 and 5000 ppm for compound 1 against pathogenic oral bacteria Enterococcus faecalis, was 8.55 and 8.05 mm, respectively. Compounds 2–3 against Streptococcus mut

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Dissertations / Theses on the topic "Phloroglucinol compound"

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Cox, Brad M. "Towards renewable commodity chemicals biosynthesis of phloroglucinol and chemoenzymatic synthesis of caprolactam /." Diss., Connect to online resource - MSU authorized users, 2008.

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Hameed, Nuzhat S. "Biodegradation of phloroglucinol and gallic acid by the soil fungus Penicillium simplicissimum /." 1987. http://collections.mun.ca/u?/theses2,13863.

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Costa, Eduarda Sofia Lopes. "Anticancer Effects of The Seaweed Compounds Fucoxanthin And Phloroglucinol, Alone And in Combination With 5-Fluorouracil in Colon Cells." Master's thesis, 2015. https://repositorio-aberto.up.pt/handle/10216/82418.

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Costa, Eduarda Sofia Lopes. "Anticancer Effects of The Seaweed Compounds Fucoxanthin And Phloroglucinol, Alone And in Combination With 5-Fluorouracil in Colon Cells." Dissertação, 2015. https://repositorio-aberto.up.pt/handle/10216/82418.

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Yi-Hsiu, Lin, and 林怡秀. "Synthesis and Mesogenic Properties of Bent-Shaped and Discotic Liquid Crystals Composed of 5-Methyl Isophthalic Acid and Phloroglucinol." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/9cbpnh.

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碩士<br>國立高雄師範大學<br>化學系<br>97<br>Six series of compounds were synthesized to study the mesogenic properties of calamitic, bent-shaped, and discotic liquid crystals. The chemical structures of these compounds were characterized by 1H-NMR, 13C-NMR, IR spectra, MS as well as elemental analyses. The identification of liquid crystal phases is based on the results of DSC measurements, POM observation, and XRD experiments. Some conclusions are summarized as follows. In series 1 and 2, the ring size of terminal cycloalkanyl groups have little influence on the formation of the liquid crystal pha

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Book chapters on the topic "Phloroglucinol compound"

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of trinuclear copper(II) complex with tris-cyclam based on phloroglucinol." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 4. Springer Berlin Heidelberg, 2021. http://dx.doi.org/10.1007/978-3-662-62474-6_293.

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Böhm, S., A. Winkel, M. Kahlmeyer, B. Fazliu, M. Horn, and T. Fuhrmann-Lieker. "Algae-Based Phlorotannins as a Sustainable Feedstock for Epoxy Resin Formulation." In Lecture Notes in Mechanical Engineering. Springer Nature Switzerland, 2025. https://doi.org/10.1007/978-3-031-77429-4_89.

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AbstractBisphenol A is the most important chemical for producing epoxy resins, but as of today is not bio-based accessible. Furthermore, it is rated as a substance of very high concern and possesses reproductive toxic and endocrine-disrupting properties. Phlorotannins, a class of polyphenols, are structurally highly suited for serving as sustainable bisphenol A alternatives. They are largely found in brown algae, which are already being harvested for alginate production. Phlorotannins thus represent a promising marine raw material for the chemical industry which otherwise has received little a

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Tchangoue Ngandjui, Yvan Anderson, Niranjan Das, Subhash C. Mandal, and Simeon Fogue Kouam. "Pharmacological Potential of Bioactive Phloroglucinol Compounds of the Plant Kingdom." In Therapeutic Insights into Herbal Medicine through the Use of Phytomolecules. BENTHAM SCIENCE PUBLISHERS, 2024. http://dx.doi.org/10.2174/9789815238129124030003.

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Historically, natural products, which are substances generated by living organisms found in nature, have made an important contribution to pharmacotherapy, especially those from plant sources. Phloroglucinols are significant bioactive polyphenolic compounds that are found in plants, marine and microbial sources. Their chemical structures include an aromatic phenyl ring with three hydroxyl groups and are usually made of two or more rings linked together through methylene bridges. They exist widely in several plant families and are known for their significant biological potentials, such as antib

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Singh, Anushka, and Paranjeet Kaur. "Harnessing Marine-Derived Compounds for Cardiovascular Health." In Advances in Medical Technologies and Clinical Practice. IGI Global, 2024. http://dx.doi.org/10.4018/979-8-3693-5878-8.ch010.

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Cardiovascular diseases [CVD] is one of the main cause of death and disability that can be prevented by leading a healthy lifestyle. Bioactive compounds from natural marine sources have gained a lot of interest. Marine sources serve as reservoirs for new bioactive metabolites with various pharmacological activities. Innumerable products derived from marine sources have been widely used across the globe by traditional practitioners for thousands of years. Marine pharmacology has been reviewed extensively in the past all over the world as well as India, but still there is a need to review the po

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Negi, Anoop Singh, Rekha Jethi, Santosh Kumar, and Ankit Kumar. "THE PHARMACOLOGICAL POTENTIAL OF ASPIDINOL – A PROMISING PHYTOCONSTITUENT." In Futuristic Trends in Pharmacy & Nursing Volume 3 Book 1. Iterative International Publishers, Selfypage Developers Pvt Ltd, 2024. http://dx.doi.org/10.58532/v3bipn1p2ch5.

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Phytoconstituents possess diverse biological activities including medicinal, therapeutic, and nutritional as well as play vital roles in the plant's growth, development, interactions with other organisms, defense against pathogens and to attract pollinators. Various groups of phytoconstituents, such as alkaloids, tannins, flavonoids, , glycosides, saponin,s terpenoids, lignans, and resins, are found in different plant species, demonstrating efficacy and potency in providing health benefits for humans and animals. Phytoconstituents have been integral to systems of traditional medicine for centu

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