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Journal articles on the topic 'Phthalamide'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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1

McClelland, Robert A., N. Esther Seaman, James M. Duff, and R. E. Branston. "Kinetics and equilibrium in the ammonolysis of substituted phthalimides." Canadian Journal of Chemistry 63, no. 1 (1985): 121–28. http://dx.doi.org/10.1139/v85-020.

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Kinetic studies are reported for the base hydrolysis to phthalamic acid anions (H) and ammonolysis to phthalamides (A) for seven phthalimides (P): 1, unsubstituted; 2, 4-NO2; 3, 4-Cl; 4, 4-t Bu; 5, 3-NO2; 6, 3-Me; 7, 3-Me3Si. The hydrolysis kinetics require two mechanisms, one which is first order in neutral imide and first order in hydroxide ion, and a second, which is important only in quite concentrated NaOH, which is first order in neutral phthalimide and second order in hydroxide ion. Ammonolysis kinetics for 1–5 revealed the rate law: Rate = kN [Unionized phthalimide] [NH3][OH−]. A mecha

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2

Yaprak, Yıldız, HülyaAkgün, Sipahi Hande, Deniz İnci, and Berk Barkın. "Synthesis, Characterization and Potential Anticancer and Antimicrobial Activities of New Phthalamide Derivatives." Pharmaceutical and Chemical Journal 6, no. 1 (2019): 72–83. https://doi.org/10.5281/zenodo.13931678.

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A series of N<sup>1</sup>,N<sup>2</sup>-bis [(2-substitutedphenyl)ethyl]phthalamide (compounds <strong>1-10</strong>) and 3-nitro-N<sup>1</sup>, N<sup>2</sup>-bis [(2-substitutedphenyl)ethyl]phthalamide (compounds <strong>11-20</strong>) were synthesized. Their structures and purity were analyzed by IR, <sup>1</sup>H-NMR spectra and elemental analysis. The compounds were evaluated for their <em>in vitro </em>cytotoxicity against the MCF7 and Hep3B cancer cell lines. Cytotoxicity screening revealed that N<sup>1</sup>,N<sup>2</sup>-bis[2-(2,4-dichlorophenyl)ethyl]phthalamide (compound<strong> 5<

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3

Aydin, Fatma, and Erdogan Dagci. "N,N′-Bis-(4-nitrophenylcarbamothioyl)phthalamide." Molbank 2013, no. 4 (2013): M809. http://dx.doi.org/10.3390/m809.

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4

Trumbo, David L. "Copolymerization of N-vinyl phthalamide with acrylate and methacrylate monomers and preliminary analysis of the stereochemistry of poly(N-vinyl phthalamide)." Polymer Bulletin 35, no. 6 (1995): 665–70. http://dx.doi.org/10.1007/bf00294947.

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5

Baxendale, Ian, Marcus Baumann, and Ishika Saha. "Unprecedented Alkene Transposition in Phthalate–Amino Acid Adducts." Synlett 29, no. 20 (2018): 2648–54. http://dx.doi.org/10.1055/s-0037-1611294.

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A detailed account on the outcome of the thermal reaction between benzylidene phthalides and various amino acid derivatives is reported. It was discovered that the tricyclic pyrroles as previously described are not the products formed in these reactions. Instead under high-temperature conditions decarboxylated phthalamide adducts are formed within 5-10 minutes. Additionally, an unprecedented alkene transposition mechanism has been identified leading to the final products of these reactions.

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6

Zhou, Mi, Ying Shao, Yong-an Xia, Xiao-Long Liu, and Xiao-Qiang Sun. "2-[2-(4-Methylpiperazin-1-yl)ethyl]isoindoline-1,3-dione." Acta Crystallographica Section E Structure Reports Online 70, no. 3 (2014): o287. http://dx.doi.org/10.1107/s1600536814002232.

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In the title compound, C15H19N3O2, the piperazine ring adopts a chair conformation, with its N—C bonds in pseudo-equatorial orientations. The dihedral angle between the C atoms of the piperazine ring and the phthalamide ring system (r.m.s. deviaiton = 0.008 Å) is 89.30 (8)°. In the crystal, molecules are linked by C—H...O hydrogen bonds, generating a three-dimensional network and aromatic π–π interactions also occur [centroid–centroid distances = 3.556 (1)–3.716 (1) Å].

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7

Gribkova, O. L., V. A. Kabanova, E. I. Rodina, M. A. Teplonogova, L. I. Demina, and A. A. Nekrasov. "Optical Ammonia Sensors Based on Spray-Coated Polyaniline Complexes with Polysulfonic Acids." Sensors 25, no. 11 (2025): 3348. https://doi.org/10.3390/s25113348.

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The optical ammonia-sensing properties of water-dispersible polyaniline (PANI) complexes chemically synthesized in the presence of polysulfonic acids of different structure and chain flexibility were compared for the first time. Flexible-chain poly(styrene-4-sulfonic acid) and poly-(2-acrylamido-2-methyl-1-propanesulfonic acid), as well as semi-rigid-chain poly-4,4′-(2,2′-disulfonic acid)diphenylene-iso-phthalamide and rigid-chain poly-4,4′-(2,2′-disulfonic acid)diphenylene-tere-phthalamide (t-PASA) were used. The sensor films were prepared by a convenient and scalable method—spray coating of

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8

Kokorin, A. I., V. N. Kolot, and I. I. Khairullin. "EPR study of the complexes of polyhydroxyphenylbenzoxazoletere-phthalamide with VO2+ ions." Bulletin of the Academy of Sciences of the USSR Division of Chemical Science 38, no. 1 (1989): 45–49. http://dx.doi.org/10.1007/bf00953697.

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9

Atta, Ayman M., Hamad A. Al-Lohedan, Abdelrahman O. Ezzat, and Nourah I. Sabeela. "New Imidazolium Ionic Liquids from Recycled Polyethylene Terephthalate Waste for Curing Epoxy Resins as Organic Coatings of Steel." Coatings 10, no. 11 (2020): 1139. http://dx.doi.org/10.3390/coatings10111139.

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Imidazolium ionic liquid (IIL) was prepared from aminolysis of polyethylene terephthalate (PET) waste with pentaethylenehexamine (PEHA) to apply as hardener of epoxy resin. Its purified chemical structures, thermal stability, and thermal characteristics were identified as well as amino phthalamide aminolyzed products. The thermal, thermomechanical, and mechanical properties of the cured epoxy resins with different weight percentages of IIL were investigated to optimize the best weight ratio to obtain homogeneous networks. The adhesion, durability, and corrosion resistance of the cured epoxy re

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10

Chen, Youwei, Yingying Wan, Qiaoxia Liu, et al. "Synthesis and Biological Activities of Novel Analogues of Phthalamide Containing Acylurea and Acylthiourea." Chinese Journal of Organic Chemistry 35, no. 4 (2015): 882. http://dx.doi.org/10.6023/cjoc201409005.

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11

Marosvölgyi-Haskó, Diána, Andrea Petz, Attila Takács, and László Kollár. "Synthesis of tetrahydrophthalazine and phthalamide (phthalimide) derivatives via palladium-catalysed carbonylation of iodoarenes." Tetrahedron 67, no. 47 (2011): 9122–28. http://dx.doi.org/10.1016/j.tet.2011.09.095.

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12

Yue, Zhilian, Mark E. Eccleston, and Nigel K. H. Slater. "PEGylation and aqueous solution behaviour of pH responsive poly(l-lysine iso-phthalamide)." Polymer 46, no. 8 (2005): 2497–505. http://dx.doi.org/10.1016/j.polymer.2004.09.041.

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13

Penkova, Anastasia V., Galina A. Polotskaya, Alexander M. Toikka, et al. "Structure and Pervaporation Properties of Poly(phenylene-iso -phthalamide) Membranes Modified by Fullerene C60." Macromolecular Materials and Engineering 294, no. 6-7 (2009): 432–40. http://dx.doi.org/10.1002/mame.200800362.

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14

IYENGAR, Doreswamy Sundararaj, Jayalakshmi KAMAIAH, Sridhar M. ANANDALWAR, Kanchugarakoppal S. RANGAPPA, and Javaregowda S. PRASAD. "Synthesis and Crystal Structure of 2-(4-Chlorophenyl)-3-(4-phthalamide)-1,3-thiazolidin-4-one." Analytical Sciences: X-ray Structure Analysis Online 22 (2006): x181—x182. http://dx.doi.org/10.2116/analscix.22.x181.

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15

Lee, Chang-Hee, Jin-Suk Lee, Hee-Kyung Na, et al. "Cis- and Trans-Strapped Calix[4]pyrroles Bearing Phthalamide Linkers: Synthesis and Anion-Binding Properties." Journal of Organic Chemistry 70, no. 6 (2005): 2067–74. http://dx.doi.org/10.1021/jo0487146.

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16

Pulyalina, A. Yu, I. I. Faykov, A. S. Sorokina, N. S. Tian, I. S. Kuryndin, and G. A. Polotskaya. "New Hybrid Membrane Based on Poly(<i>m</i>-Phenylene-<i>iso</i>-Phthalamide) for Pervaporation of Methanol/<i>n</i>-Heptane Azeotropic Mixture." Мембраны и мембранные технологии 13, no. 4 (2023): 259–68. http://dx.doi.org/10.31857/s2218117223040053.

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The object of this work is a new hybrid membrane based on poly(m-phenylene-iso-phthalamide) (PA) modified with a complex filler consisting of equal amounts of heteroarms star macromolecules (HSM) and [BMIM+Tf2N–] ionic liquid (IL). Comparative studies of the structure were carried out on samples of membranes made of pristine PA and hybrid PA/HSM and PA/(HSM:IL) containing 5 wt % additives; methods of AFM, X-ray phase analysis, measurement of density and contact angles were used. The transport properties of membranes were studied in separation of a methanol/n-heptane mixture by the pervaporatio

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17

Snehal, A. Chavan, G. Ulhe Avinash, and N. Berad Baliram. "Synthesis, characterization and antimicrobial study of N-glucosylated 1,3-benzodiazepine-4,7-dione." Journal of Indian Chemical Society Vol. 91, Oct 2014 (2014): 1947–52. https://doi.org/10.5281/zenodo.5733910.

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Post-Graduate Department of Chemistry, Mahatma Jyotiba Phule Educational Campus, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur-440 033, Maharashtra, India <em>E-mail</em> : i_snehal123@yahoo.com <em>Manuscript received online 03 April 2014, accepted 29 April 2014</em> An efficient synthesis of 2-tetra-<em>O</em>-acetyl-β-D-glucopyranosylimino-1,3-di-<em>H</em>/aryl/alkyl-[1,2-e][1,3]benzodiazepine-4,7-dione by condensation of N,N´-di-<em>H</em>/aryl/alkyl phthalamide and <em>N</em>-tetra-<em>O</em>-acetyl-β-D-glucopyranosyl isocyanodichloride in refluxing chloroform ha

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18

Syahputra, Adi, Mudasir Mudasir, Nuryono Nuryono, Anifuddin Aziz, and Iqmal Tahir. "QSAR Study of Insecticides of Phthalamide Derivatives Using Multiple Linear Regression and Artificial Neural Network Methods." Indonesian Journal of Chemistry 14, no. 1 (2014): 94–101. http://dx.doi.org/10.22146/ijc.21273.

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Quantitative structure activity relationship (QSAR) for 21 insecticides of phthalamides containing hydrazone (PCH) was studied using multiple linear regression (MLR), principle component regression (PCR) and artificial neural network (ANN). Five descriptors were included in the model for MLR and ANN analysis, and five latent variables obtained from principle component analysis (PCA) were used in PCR analysis. Calculation of descriptors was performed using semi-empirical PM6 method. ANN analysis was found to be superior statistical technique compared to the other methods and gave a good correla

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19

Andrade-Jorge, Erik, Jessica E. Rodríguez, José Bribiesca-Carlos, Itzell A. Gallardo-Ortíz, José G. Trujillo-Ferrara, and Rafael Villalobos-Molina. "Novel phthalamide derivatives as antihypertensive agents: rapid and clean synthesis, in silico and in vivo evaluation." Medicinal Chemistry Research 28, no. 5 (2019): 681–95. http://dx.doi.org/10.1007/s00044-019-02327-3.

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20

Aydin, Fatma, and Erdoğan Dağci. "N,N’-Bis-(2,5-dimethyl-3-oxo-1-phenyl-2,3-dihydro-1H-pyrazol-4-yl)phthalamide." Molbank 2012, no. 2 (2012): M754. http://dx.doi.org/10.3390/m754.

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21

YUE, Z., M. ECCLESTON, and N. SLATER. "Modulation of the pH-responsive properties of poly(-lysine -phthalamide) grafted with a poly(ethylene glycol) analogue." Biomaterials 26, no. 32 (2005): 6357–66. http://dx.doi.org/10.1016/j.biomaterials.2005.03.035.

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22

Sim, Yoke-Leng, Azhar Ariffin, and M. Niyaz Khan. "Kinetics and Mechanism of Large Rate Enhancement in the Alkaline Hydrolysis ofN′-Morpholino-N-(2′-methoxyphenyl)phthalamide." Journal of Organic Chemistry 73, no. 10 (2008): 3730–37. http://dx.doi.org/10.1021/jo702695k.

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23

KUDRYAVTSEV, V. V., G. I. NOSOVA, N. A. SOLOVSKAYA, A. V. DOBRODUMOV, N. I. RTISHCHEV, and A. N. FROLOV. "ChemInform Abstract: Photochemical Reactions of Phthalamide Derivatives of 1,3-Diphenyl-2- prop-1-one and Its Analogues." ChemInform 27, no. 12 (2010): no. http://dx.doi.org/10.1002/chin.199612116.

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24

Sim, Yoke-Leng, Azhar Ariffin, and M. Niyaz Khan. "Kinetic Evidence for the Formation of MonocationicN,N‘-Disubstituted Phthalamide in Tertiary Amine-Catalyzed Hydrolysis ofN-Substituted Phthalimides." Journal of Organic Chemistry 72, no. 22 (2007): 8452–58. http://dx.doi.org/10.1021/jo701295n.

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25

Guzei, Ilia A., Lara C. Spencer, Robert W. McGaff, Heidi M. Kieler, and Jerome R. Robinson. "Constructor graph description of hydrogen bonding in a supramolecular assembly ofN,N′-bis(2-hydroxy-1-methylethyl)phthalamide." Acta Crystallographica Section C Crystal Structure Communications 63, no. 4 (2007): o255—o258. http://dx.doi.org/10.1107/s0108270107009146.

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26

Pulyalina, A. Yu, I. I. Faykov, A. S. Sorokina, N. S. Tian, I. S. Kuryndin, and G. A. Polotskaya. "New Hybrid Membrane Based on Poly(m-phenylene-iso-phthalamide) for Pervaporation of Methanol/n-Heptane Azeotropic Mixture." Membranes and Membrane Technologies 5, no. 4 (2023): 227–35. http://dx.doi.org/10.1134/s2517751623040054.

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27

Eccleston, M. E., S. L. Williams, Z. Yue, et al. "Design and In-vitro Testing of Effective Poly(l-Lysine Iso-Phthalamide) Based Drug Targeting Systems for Solid Tumours." Food and Bioproducts Processing 83, no. 2 (2005): 141–46. http://dx.doi.org/10.1205/fbp.04401.

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28

Khormaee, Sariah, Rongjun Chen, John K. Park, and Nigel K. H. Slater. "The Influence of Aromatic Side-Chains on the Aqueous Properties of pH-Sensitive Poly(L-lysine iso-phthalamide) Derivatives." Journal of Biomaterials Science, Polymer Edition 21, no. 12 (2010): 1573–88. http://dx.doi.org/10.1163/092050609x12519805626194.

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29

Lyutov, Vladimir, Varvara Kabanova, Oxana Gribkova, Alexander Nekrasov, and Vessela Tsakova. "Electrochemically-Obtained Polysulfonic-Acids Doped Polyaniline Films—A Comparative Study by Electrochemical, Microgravimetric and XPS Methods." Polymers 12, no. 5 (2020): 1050. http://dx.doi.org/10.3390/polym12051050.

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Polyaniline (PANI) layers are electrochemically obtained in the presence of four polysulfonic acids with different rigidities of the polymer backbone-iso-(and tere-)poly-(4,4′-(2,2′-disulfonic acid)-diphenylene-iso(tere)-phthalamide (i-PASA and t-PASA), polystyrenesulfonic acid (PSSA) and poly(2-acrylamido-2-methyl-1-propanesulfonic acid) (PAMPSA). Combined microgravimetric (EQCM) and electrochemical measurements are carried out in the course of polymerization and repetitive redox switching. It is found that after synthesis PASA-doped PANIs shows good stability with low exchange of mass in the

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30

Andrade-Jorge, Erik, Jessica E. Rodríguez, Jesús A. Lagos-Cruz, et al. "Phthalamide derivatives as ACE/AChE/BuChE inhibitors against cardiac hypertrophy: an in silico, in vitro, and in vivo modeling approach." Medicinal Chemistry Research 30, no. 4 (2021): 964–76. http://dx.doi.org/10.1007/s00044-021-02707-8.

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31

Dai, Xiaowen, Mark E. Eccleston, Zhilian Yue, Nigel K. H. Slater, and Clemens F. Kaminski. "A spectroscopic study of the self-association and inter-molecular aggregation behaviour of pH-responsive poly(l-lysine iso-phthalamide)." Polymer 47, no. 8 (2006): 2689–98. http://dx.doi.org/10.1016/j.polymer.2006.02.059.

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32

Nasser, Nasser, and Richard J. Puddephatt. "Supramolecular chemistry of the ligand N,N’-bis(2-diphenylphosphinoethyl)phthalamide and its complexes with gold(I) and silver(I)." Inorganica Chimica Acta 409 (January 2014): 238–43. http://dx.doi.org/10.1016/j.ica.2013.09.024.

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33

Dauda, Aminu, Auwal A. Mahmoud, H. M. Adamu, and Abdul Ademola Olaleye. "Synthesis and Characterization of Metal Phthalocyanine Complex Using Substituted 4-Nitrophthalonitrile Ligand." European Journal of Theoretical and Applied Sciences 1, no. 6 (2023): 1054–68. http://dx.doi.org/10.59324/ejtas.2023.1(6).102.

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In this research work, four compounds: 4-nitrophthalamide, 4-nitrophthalonitrile and 4-(ciproxy) phthalonitrile and phthalocyanine complex were synthesized. The synthesis began with the nitration in the position 4 of phthalamide which led to the formation of 4-nitrophthalamide. Dehydration by the thionyl chloride in N,N-dimethylformamide (DMF) led to the formation of 4-nitrophthalonitrile and further reaction of ciprofloxacin with 4-nitrophthalonitrile in DMF forms the phthalonitrile derivative, cyclotetramerization of 4-(ciproxy) phthalonitrile in the presence of nickel salt gave substituted

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34

Aminu, Dauda, A. Mahmoud Auwal, Adamu H.M., and Ademola Olaleye Abdul. "Synthesis and Characterization of Metal Phthalocyanine Complex Using Substituted 4-Nitrophthalonitrile Ligand." European Journal of Theoretical and Applied Sciences 1, no. 6 (2024): 1054–68. https://doi.org/10.59324/ejtas.2023.1(6).102.

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In this research work, four compounds: 4-nitrophthalamide, 4-nitrophthalonitrile and 4-(ciproxy) phthalonitrile and phthalocyanine complex were synthesized. The synthesis began with the nitration in the position 4 of phthalamide which led to the formation of 4-nitrophthalamide. Dehydration by the thionyl chloride in N,N-dimethylformamide (DMF) led to the formation of 4-nitrophthalonitrile and further reaction of ciprofloxacin with 4-nitrophthalonitrile in DMF forms the phthalonitrile derivative, cyclotetramerization of 4-(ciproxy) phthalonitrile in the presence of nickel salt gave substituted

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35

Gong, Yun, Jian Li, Peng-Gang Jiang, Qing-Fang Li, and Jian-Hua Lin. "Novel metal(ii) coordination polymers based on N,N′-bis-(4-pyridyl)phthalamide as supercapacitor electrode materials in an aqueous electrolyte." Dalton Trans. 42, no. 5 (2013): 1603–11. http://dx.doi.org/10.1039/c2dt31965a.

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36

Kretschmer, Axel, Robert Drake, Michael Neidhoefer, and Manfred Wilhelm. "Quantification of Composition and Domain Sizes of Industrial Poly(phthalamide)/Poly(dimethylsiloxane) Block Copolymers Using Different 1H Solid State NMR Methods." Solid State Nuclear Magnetic Resonance 22, no. 2-3 (2002): 204–17. http://dx.doi.org/10.1006/snmr.2002.0068.

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37

Vandenberg, E. J., W. R. Diveley, L. J. Filar, S. R. Patel, and H. G. Barth. "The synthesis and solution properties of some rigid-chain, water-soluble polymers: Poly[N,N′-(sulfo-phenylene)phthalamide]s and poly[N,N′-(sulfo-p-phenylene)pyromellitimide]." Journal of Polymer Science Part A: Polymer Chemistry 27, no. 11 (1989): 3745–57. http://dx.doi.org/10.1002/pola.1989.080271115.

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38

Sim, Yoke-Leng, and M. Niyaz Khan. "Kinetics and mechanism of tertiary amine-catalyzed cleavage ofN′-morpholino-N-(2′-methoxyphenyl)phthalamide: Kinetic evidence for the presence of a reactive intermediate on the reaction path." International Journal of Chemical Kinetics 42, no. 5 (2010): 263–72. http://dx.doi.org/10.1002/kin.20477.

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39

Lasri, Jamal, Maximilian N Kopylovich, M. Fátima C Guedes da Silva, M. Adília Januário Charmier, and Armando J L. Pombeiro. "Metal-Free and PdII-Promoted [2+3] Cycloadditions of a Cyclic Nitrone to Phthalonitriles: Syntheses of Oxadiazolines as well as Phthalamide-PdIIand Dihydropyrrolyl-iminoisoindolinone-PdIIComplexes with High Catalytic Activity in Suzuki-Miyaura Cross-Coupling Reactions." Chemistry - A European Journal 14, no. 30 (2008): 9312–22. http://dx.doi.org/10.1002/chem.200800510.

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40

Al-Hakimi, Ahmed N., Mohamad M. E. Shakdofa, Ahemd M. A. El-Seidy, and Abdou S. El-Tabl. "Synthesis, Spectroscopic, and Biological Studies of Chromium(III), Manganese(II), Iron(III), Cobalt(II), Nickel(II), Copper(II), Ruthenium(III), and Zirconyl(II) Complexes of N1,N2-Bis(3-((3-hydroxynaphthalen-2-yl)methylene-amino)propyl)phthalamide." Journal of the Korean Chemical Society 55, no. 3 (2011): 418–29. http://dx.doi.org/10.5012/jkcs.2011.55.3.418.

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41

Ismail, M. Fekry, E. I. Enayat, F. A. El-Bassiouny, and H. A. Younes. "Reaction of N-Arylphthalisoimidium Perchlorates with Amines and Aromatic Hydrocarbons under Friedel-Crafts Conditions, a New and Convenient One-Step Method for the Synthesis of 2,3-Diaryl-3-hydroxyphthalimidines." Zeitschrift für Naturforschung B 45, no. 5 (1990): 707–10. http://dx.doi.org/10.1515/znb-1990-0520.

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N-Arylphthalisoimidium perchlorates (1 a, b) react with primary amines via ring-opening to give N,N′-disubstituted phthalamides (3a—d). They react with aromatic hydrocarbons under Friedel-Crafts conditions to give 2,3-diaryl-3-hydroxyphthalimidines (a—i) while the reaction of 1 a with phenylmagnesium bromide involved just deprotonation to the isoimide (9) followed by rearrangement to N-phenylphthalimide (8).

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42

Waddell, Paul G., Rupert J. Rutledge, and Jacqueline M. Cole. "N-(2-Methoxyphenyl)phthalamic acid." Acta Crystallographica Section E Structure Reports Online 69, no. 6 (2013): o930. http://dx.doi.org/10.1107/s1600536813013408.

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43

Fabiyi, O. A., A. O. Claudius-Cole, and G. A. Olatunji. "In Vitro Assessment of N-Phenyl Imides in the Management of Meloidogyne Incognita." Scientia Agriculturae Bohemica 52, no. 3 (2021): 60–65. http://dx.doi.org/10.2478/sab-2021-0007.

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Abstract The infestation with root knot nematode Meloidogyne spp. is a key issue in agriculture. Conventional control methods are based on the use of synthetic nematicides, which comes with severe environmental problems. In this study, n-phenyl imide and n-phenyl phthalamic acid were synthesized and reacted independently with Enantia chlorantha crude extract–manganese chloride complex. The effects of the resulting organic compounds were appraised against the root knot nematode Meloidogyne incognita (Kofoid and White 1919) juveniles and eggs in two laboratory experiments. The most active compou

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44

Mills, R. J., R. F. Horvath, M. P. Sibi, and V. Snieckus. "Dilithiated synthons of tertiary benzamides, phthalamides, and 0,0′-aryl dicarbamates." Tetrahedron Letters 26, no. 9 (1985): 1145–48. http://dx.doi.org/10.1016/s0040-4039(00)98418-1.

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45

Racskó, József. "N-Phenyl-Phthalamic Acid and Fertilization Effects on Flowering, Fruit Set and Fruit Quality of Apple (Malus domestica Borkh.)." Acta Agraria Debreceniensis, no. 24 (October 11, 2006): 24–28. http://dx.doi.org/10.34101/actaagrar/24/3220.

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On seven apple cultivars (Gala Must, Gloster, Granny Smith, Idared, Jonagold, Jonathan Csány 1, Mutsu), the authors studied the influence of N-phenyl-phthalamic (PPA) acid and fertilization on flowering, fruit set and fruit quality in the years 2003-2004. The research results showed that PPA application extended the flowering time of the most cultivars. Fruit set of apple cultivars increased in many cases when regulator was applied. The additional nutrient supply could increase the fruit set too. The increase of fruit set increased the number of fruit per tree. Quality parameters determined by

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Liu, Ming, Yi Wang, Wei-zi Wangyang, et al. "Design, Synthesis, and Insecticidal Activities of Phthalamides Containing a Hydrazone Substructure." Journal of Agricultural and Food Chemistry 58, no. 11 (2010): 6858–63. http://dx.doi.org/10.1021/jf1000919.

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Chen, Youwei, Yuxin Li, Li Pan, et al. "Synthesis, insecticidal activities and SAR of novel phthalamides targeting calcium channel." Bioorganic & Medicinal Chemistry 22, no. 22 (2014): 6366–79. http://dx.doi.org/10.1016/j.bmc.2014.09.052.

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Sharutin, V., O. Sharutina, V. Zubareva, and A. Chernyshova. "Interaction of pentaphenylantimony with N-(4-methoxyphenyl)phthalamic acid." Bulletin of the South Ural State University series "Chemistry" 16, no. 3 (2024): 97–104. http://dx.doi.org/10.14529/chem240303.

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Pentaphenylantimony reacts with N-(4-methoxyphenyl)phthalamic acid in benzene at room temperature to form colorless crystals of tetraphenylantimony carboxylate solvated by benzene Ph4SbOC(O)C6H4[2-C(O)NHC6H4(OMe-4)]∙1½ PhH (1a, b), the structure of which is proven by X-ray diffraction analysis (XRD). According to the X-ray diffraction data, the antimony atoms in two crystallographically independent molecules 1a,b have the coordination of a distorted trigonal bipyramid with three phenyl substituents in the equatorial plane, while the CSbO axial angles are 173.7(2)° and 179.0(2)°, and the Sb–Ceq

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McCormac, Paul B., Albert C. Pratt, Conor Long, and R. Alan Howie. "(S)-N-(1-Benzyl-2-hydroxyethyl)phthalamic acid." Acta Crystallographica Section E Structure Reports Online 61, no. 7 (2005): o2047—o2049. http://dx.doi.org/10.1107/s160053680501740x.

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Khushal, Aneela, Umar Farooq, Sara Khan та ін. "Bioactivity-Guided Synthesis: In Silico and In Vitro Studies of β-Glucosidase Inhibitors to Cope with Hepatic Cytotoxicity". Molecules 28, № 18 (2023): 6548. http://dx.doi.org/10.3390/molecules28186548.

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The major cause of hyperglycemia can generally be attributed to β-glucosidase as per its involvement in non-alcoholic fatty liver disease. This clinical condition leads to liver carcinoma (HepG2 cancer). The phthalimides and phthalamic acid classes possess inhibitory potential against glucosidase, forming the basis for designing new phthalimide and phthalamic acid analogs to test their ability as potent inhibitors of β-glucosidase. The study also covers in silico (molecular docking and MD simulations) and in vitro (β-glucosidase and HepG2 cancer cell line assays) analyses. The phthalimide and

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