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Journal articles on the topic 'Piper Betel Leaves'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Pramesti, Kadesha. "Determination Of The Difference Handrub Boiled Betel Leaf (Piper Betle) Compared Alcohol On The Percentage Of Reducing The Number Of Microorganism Colony." Media Farmasi Indonesia 20, no. 1 (2025): 76–86. https://doi.org/10.53359/mfi.v20i1.317.

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tel leaf (Piper Betle Linn) is one of the natural ingredients that can be used as a substitute for alcohol in hand sanitizers. This study aims to analyze the differences in handrubs from boiled betel leaves (Piper betle) compared to 70% alcohol on the percentage of reduction in the number of microorganism colonies. The type of research conducted was experimental research with a Pre Post Test Group Design research design. Sampling was carried out by Concutive Sampling from Students of the Faculty of Medicine, Sultan Agung Islamic University, Semarang through the glove juice method with a total

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2

Junairiah, Junairiah, Ni’matuzahroh Ni’matuzahroh, Nabilah Istighfari Zuraidassanaaz, and Lilis Sulistyorini. "ISOLATION AND IDENTIFICATION OF SECONDARY METABOLITES OF BLACK BETEL (Piper betle L. var Nigra)." Jurnal Kimia Riset 3, no. 2 (2019): 131. http://dx.doi.org/10.20473/jkr.v3i2.12064.

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AbstractPiper betle L. var Nigra commonly known as black betel have a potential as drug raw materials. The leave of black betel can be used to resist bleeding so as to accelerate the healing of wounds on the skin, sputum, other uses are for epistaxis, as well as for dialysis, asthma, bronchitis, cough, and high blood pressure. Many uses of black betel leaves make it interesting to learn its metabolites compounds by phytochemical screening. So, this research aimed to isolate and identificate secondary metabolites of Piper betle L. var Nigra. This research used three kind of organic solvents, th

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3

Eka Putri, Cici Nur Aisyah, Masyhudi Masyhudi, and Listiyawati Listiyawati. "Testing the Antibacterial Activity of Black Betel Leaf Extract (Piper betle L. Var Nigra) on Streptococcus mutans, Porphyromonas gingivalis, and Enterococcus faecalis." Jurnal Impresi Indonesia 3, no. 7 (2024): 497–513. http://dx.doi.org/10.58344/jii.v3i7.5269.

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Black betel leaves (Piper betle L. var nigra) are known to have antibacterial effects caused by secondary metabolites such as tannins, phenolic compounds, saponins, flavonoids, alkaloids, and steroids. This study aims to assess the antibacterial activity of ethanol extract of black betel leaves (Piper betle L. var nigra) against S. mutans, P. gingivalis, and E. faecalis by measuring the diameter of the inhibition zone formed. This research is a type of pure experimental research (true experimental) with post test only control group design. This experimental research was conducted using the dis

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4

Nerdy, Nerdy, Puji Lestari, Jon Piter Sinaga, et al. "Brine Shrimp (Artemia salina Leach.) Lethality Test of Ethanolic Extract from Green Betel (Piper betle Linn.) and Red Betel (Piper crocatum Ruiz and Pav.) through the Soxhletation Method for Cytotoxicity Test." Open Access Macedonian Journal of Medical Sciences 9, A (2021): 407–12. http://dx.doi.org/10.3889/oamjms.2021.6171.

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Traditional medicine is currently being explored and developed widely by various countries because its cost effectiveness and reduced side effects. The green betel (Piper betle Linn.) and the red betel (Piper crocatum Ruiz and Pav.) are plants from the same Piper genus that are widely cultivated in Indonesia and have various phytochemical properties and pharmacological effects. The objective of this research is to determine the cytotoxicity of green leaves and red betel leaves. This research was conducted in two main stages: first, the extraction and preparation through the soxhletation method

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5

Ni Luh Putu Taksayani Putri and Ni Luh Putu Vidya Paramita. "REVIEW AKTIVITAS ANTIBAKTERI EKSTRAK DAUN SIRIH HIJAU (Piper betle L.) METODE DIFUSI DAN MIKRODILUSI." JOURNAL SCIENTIFIC OF MANDALIKA (JSM) e-ISSN 2745-5955 | p-ISSN 2809-0543 4, no. 2 (2023): 6–18. http://dx.doi.org/10.36312/10.36312/vol4iss2pp6-18.

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Green betle plant (Piper betle L.) is a type of plant that is widely used for medicine. Parts of the betel plant (Piper betle L.) such as roots, seeds, and leaves have potential for treatment, but the most frequently used are the leaves. Empirically betel leaves are used by the community as an antibacterial. There are many literature and research studies that report the antibacterial activity of green betel leaves. In this review, we will discuss green betel leaf extract using various solvents using two antibacterial methods, namely the diffusion and microdilution methods. Library searches wer

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6

Weinreb, Robert N. "REVIEW OF ANTIBACTERIAL ACTIVITY OF GREEN BETEL LEAF EXTRACT (Piper betle L.) METHODS OF DIFFUSION AND MICRODILUTION." Join: Journal of Social Science 1, no. 1 (2024): 1–18. http://dx.doi.org/10.59613/q6zxqm74.

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Green betle plant (Piper betle L.) is a type of plant that is widely used for medicine. Parts of the betel plant (Piper betle L.) such as roots, seeds, and leaves have potential for treatment, but the most frequently used are the leaves. Empirically betel leaves are used by the community as an antibacterial. There are many literature and research studies that report the antibacterial activity of green betel leaves. In this review, we will discuss green betel leaf extract using various solvents using two antibacterial methods, namely the diffusion and microdilution methods. Library searches wer

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7

Zar’ah, Nurul Atika, Syachruddin Syachruddin, and Kusmiyati Kusmiyati. "The Effect of Green Betel Leaves (Piper betle L.) Extract on Wounding Healing in Mice (Mus musculus L.)." Jurnal Biologi Tropis 21, no. 1 (2021): 103. http://dx.doi.org/10.29303/jbt.v21i1.2282.

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Green betel leaf (Piper betle L.) contains secondary metabolites, namely alkaloids, flavonoids, steroids, terpenoids, saponins, tannins. Green betel leaf (Piper betle L.) is widely used for wound healing, especially in rural Indonesians. This study aims to determine the effect of green betel leaves extract (Piper betle L.) on wound healing in mice (Mus musculus L.). The samples were determined using a randomized block design (RBD) using mice (Mus musculus L.) which consisted of three treatment groups using a concentration of 20%, 30%, 40% and one control group. The Measure of the average diame

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8

Hardianti, Novy, Henny Henny, and Taufik Delfian. "Effectiveness of Dermapen Action Using Green Belt Leaf Extract Cream (Piper betle L) On Hair Growth on The Skin Surface of Female Wistar Strain Rats (Rattus Norvegicus)." International Journal of Health and Pharmaceutical (IJHP) 3, no. 4 (2023): 954–59. http://dx.doi.org/10.51601/ijhp.v3i4.311.

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Hair loss is a very prevalent hair issue. Hair loss is typical for all humans, but if it becomes severe, it can lead to baldness. Hair goes through a unique cycle of development and loss for each strand, and one herbal plant that has the activity of fertilizing hair growth and overcoming the problem of hair loss is green betel leaf (Piper betle L). The purpose of this study was to determine the efficacy of a derma pen utilizing green betel leaf extract cream (Piper betle L) on hair development on the skin surface of female Wistar rats (Rattus norvegicus). Betel leaves have been shown to help w

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9

Harahap, Cory, Susi Yanti, Ira Nova, and Sofiyah Natunna. "Formulasi Ekstrak Daun Sirih Hijau ( Piper Betle L) Sebagai Anti Jerawat." Jurnal Kesehatan Ilmiah Indonesia (Indonesian Health Scientific Journal) 8, no. 2 (2023): 175. http://dx.doi.org/10.51933/health.v8i2.1239.

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Abstrak Daun sirih hijau (Piper betle L.) mengandung flavanoid yang cukup baik dalam menghambat pertumbuhan bakteri penyebab jerawat, salah satunya Propionibacterium acnes. Tujuan penelitian ini adalah untuk mengetahui bedak tabur anti jerawat ekstrak daun sirih hijau (Piper betle L.) dapat menghabat pertumbuhan bakteri Propionibacterium acnes, dan untuk mengetahui ekstrak daun sirih hijau (Piper betle L.) dapat diformulasikan menjadi sediaan bedak tabur anti jerawat. Menggunakan metode eksperimental. Hasil penelitian pada uji skrining fitokimia positif mengandung flavanoid, tanin, sapon

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10

Chowdhury, A., Nikhil Kumar, and R. Chaurasia. "Biochemical investigations on Betel leaves (Piper betle Linn.)." Journal of Non-Timber Forest Products 9, no. 3/4 (2002): 151–53. http://dx.doi.org/10.54207/bsmps2000-2002-170rw3.

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Betel leaves along with areca nut and spices are used as a masticatory in the sub-continent. The leaves are aromatic with varied taste ranging from sweet to pungent. The concentration and composition of essential oil influence the aroma and flavour of the leaves. Besides essential oil, chlorophylls, carotenoids, proteins, sugars, moisture percentage determine the taste and quality of leaves.

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11

Nayaka, Ni Made Dwi Mara Widyani, Maria Malida Vernandes Sasadara, Dwi Arymbhi Sanjaya, et al. "Piper betle (L): Recent Review of Antibacterial and Antifungal Properties, Safety Profiles, and Commercial Applications." Molecules 26, no. 8 (2021): 2321. http://dx.doi.org/10.3390/molecules26082321.

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Piper betle (L) is a popular medicinal plant in Asia. Plant leaves have been used as a traditional medicine to treat various health conditions. It is highly abundant and inexpensive, therefore promoting further research and industrialization development, including in the food and pharmaceutical industries. Articles published from 2010 to 2020 were reviewed in detail to show recent updates on the antibacterial and antifungal properties of betel leaves. This current review showed that betel leaves extract, essential oil, preparations, and isolates could inhibit microbial growth and kill various

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12

Gustiani, Srie, Wulan Septiani, Cica Kasipah, Danny Sukardan, and Qomarudin Helmy. "Antimicrobial Effect of Piper betle Leaves Extract on Cotton Fabrics for Vaginal Discharge Sanitary Napkins." Advanced Materials Research 1162 (April 2021): 159–65. http://dx.doi.org/10.4028/www.scientific.net/amr.1162.159.

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The betel (Piper betle) leaves have been using for traditional medicine in several tropical countries, like Indonesia. The betel leaves have the antimicrobial property for inhibiting the growth of microbes. In this study, cotton fabric was treated with the betel leaves extract 1, 5 and 10 g/l. The peper betel leaves are extracted by using boiling water up to half. The betel leaf extract was imparted onto the cotton fabrics for underclothes apparel using a pad-dry-cure. The antimicrobial activity property of treat cotton fabrics was assessed (Escherchia coli, Staphylococcus aureus, Lactobacillu

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13

Arifin, Siti Hakimah Aprilia Garini, Nirmala Fitria Firdhausi, Irul Hidayati, and Hanik Faizah. "Phytochemical Screening and Antimicrobial Activity of Combination of Piper betle and Moringa oleifera Extracts." Indonesian Journal of Pharmaceutical Science and Technology 12, no. 2 (2025): 184–91. https://doi.org/10.24198/ijpst.v12i2.45288.

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The inappropriate use of antibiotics can lead to pathogenic bacteria developing multiple drug resistance, making infectious disease treatment crucial. Thus, the discovery of novel antibiotics from natural materials, such as plant extracts or their combinations, is critically needed. Extracts of green betel (Piper betle) and Moringa (Moringa oleifera) leaves are known to have antimicrobial activity. This study aimed to determine the chemical content and antimicrobial activity of ethanol extracts of the combination of green betel leaves and Moringa leaves against Staphylococcus aureus, Escherich

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14

Resti, Indah Ana, and Dwi Ningsih. "Aktivitas Penyembuhan Luka Infeksi Krim Kombinasi Daun Sirsak (Annona muricata L.) Dan Daun Sirih (Piper betle L.) Dengan Bakteri Staphylococcus aureus Pada Punggung Kelinci New Zealand White Secara In Vivo." Jurnal Fitofarmaka Indonesia 9, no. 2 (2022): 25–32. http://dx.doi.org/10.33096/jffi.v9i2.879.

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Several types of tropical plants in Indonesia that contain anti-bacterial chemical compounds such as tannins, flavonoids and saponins, namely betel (Piper betle L.) leaves and soursop (Annona muricata L.) leaves. Objectives of the research was to determine activity of cream from soursop (Annona muricata L.) leaves ethanol extract and betel (Piper betle L.) leaves ethanol extract on the backs of rabbits infected with Staphylococcus aureus bacteria. In addition, the research conducted could also determine the stability of cream that produced and its pharmacological effects. Data analysis techniq

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15

Evani, Safira, Litalia Early Katreen Juniar, and Meyke Herina Syafitri. "Quantification of Total Phenol Concentration in Ethanol Extracts of Red and Black Betel Leaves Using UV-Vis Spectrophotometric." Journal Pharmasci (Journal of Pharmacy and Science) 9, no. 1 (2024): 29–33. http://dx.doi.org/10.53342/pharmasci.v9i1.388.

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Red betel (Piper crocatum Ruiz & Pav) and black betel leaves (Piper betle var. nigra) are plant varieties known for their medicinal properties. These plants have various contents including flavonoids, essential oils, tannins and polyphenols. The objective of this research is to ascertain the quantity of phenolic compounds present in ethanol extracts of red and black betel leaves. Determination of the levels of ethanol extracts of red and black betel leaves is done quantitatively by the folin-ciocalteu method. This method relies on the formation of a blue complex compound of of phosphomolyb

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16

Ferlita Shafri Djohan, Frita, Herryawan Herryawan, and Fahrauk Faramayuda. "MACROSCOPIC AND QUALITATIVE PHYTOCHEMICAL EXAMINATION OF RED BETEL LEAVES AND GREEN BETEL LEAVES AS HERBAL MEDICINE FOR GINGIVITIS." Journal of Health and Dental Sciences, Volume 2 No 2 (September 30, 2022): 355–64. http://dx.doi.org/10.54052/jhds.v2n2.p355-364.

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Gingivitis is inflammation of the gums that occurs in response to plaque bacteria that become more easily accumulated and difficult to clean in the gum area. The Red betel plant (Piper crocatum) and green betel leaf (Piper betle L.) are plant species from the Piperaceae family empirically used as antibacterial in gingivitis patients due to the presence of secondary metabolite compounds used as medicine. This study aims to determine the macroscopic description and the content of qualitative phytochemical compounds in red betel leaf and green betel leaf. The research method of this study was a l

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17

Verma, Neha, and Basudha Singh Gautam. "Piper betle: Deep Insights into the Pharmacognostic and Pharmacological Perspectives." International Journal of Medical & Pharmaceutical Sciences 13, no. 02 (2023): 04–15. http://dx.doi.org/10.31782/ijmps.2023.13202.

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Piper betle L., belonging to Piperaceae family, referred to as a standard herbal medicinal plant and used for several health benefits in Asian countries. Currently, demand for its products like herbal drugs, medicines, and natural herbal formulations have increased. The beneficial effects of betel leaves and its products have traditionally exploited for the treatment of several diseases like bad breath, cuts, injuries, inflammations, cold cough, indigestion, etc. Till now, a broad range of bioactive compounds including polyphenols, terpenes, etc., has been identified from the extracts and vola

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18

Parhusip, Adolf J. N., Sabrina A. Putridimara, Elin Kristianto, Alfredo Alfredo, and Jesseline Fraulencia. "Pemanfaatan Ekstrak Kasar Daun Sirih Hijau (Piper betle) dan Daun Sirih Merah (Piper crocatum) Sebagai Antimikroba Pada Daging Ayam Broiler Segar." JURNAL BIOLOGI PAPUA 15, no. 2 (2023): 119–29. http://dx.doi.org/10.31957/jbp.2881.

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Green betel plants (Piper betle) and red betel plants (Piper crocatum) are plants that found in many parts of Indonesia which can be categorized as medicinal plants. This is due to the content contained in green and red betel leaves which has phenolic compounds, such as flavonoids, tannins, and saponins. The research objective of this study was to utilize the extract of green betel leaf and red betel leaf by extracting ethanol FG 96% as an antimicrobial compound. There are 4 types of tested bacteria used in this study, they are Escherichia coli, Salmonella, S. aureus, and B. cereus. The extrac

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Fahmah, Nur Izzatul, Metty Amperawati, and Isnawati Isnawati. "PENGARUH BERKUMUR REBUSAN DAUN SIRIH (Piper betle L.) TERHADAP pH SALIVA PADA LANSIA." JURNAL TERAPIS GIGI DAN MULUT 5, no. 2 (2025): 51–55. https://doi.org/10.31964/jtgm.v5i2.117.

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Increasing age is also accompanied by many dental and oral problems. Teeth and saliva decreased function resulting in demineralization of the enamel surface. Betel leaves contain ingredients that can strengthen teeth and clear the throat. This study aims to determine the effect of gargling boiled betel leaves (Piper betle L.) on salivary pH in the elderly. The research method used was a quasi experiment with a one group pretest-posttest design. The research sample consisted of 41 people using purposive sampling technique. Data were analyzed using the paired sample t-test. The research results

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20

Johri, S., N. Khan, and S. Shrivastava. "ANTI-ANAEMIC POTENTIAL OF BUTANOLIC EXTRACT OF PIPER BETEL LEAVES AND TRITICUM AESTIVUM GRASS IN RATS: AN IN VIVO APPROACH." INDIAN DRUGS 56, no. 01 (2019): 40–44. http://dx.doi.org/10.53879/id.56.01.11550.

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Several plants have been used for medicinal purposes since long. Piper betel and Triticum aestivum are traditionally used as herbal medicines. The objective of this study was to estimate the antianaemic potential of butanolic extract of Piper betel leaves and Triticum aestivum grass in a rat model. Butanolic extract of Piper betel leaves and Triticum aestivum grass were prepared by soxhalation. Anaemia was induced by intraperitoneal administration of phenylhydrazine in female rats at doses of 20mg/kg body weight/day for 6 consecutive days. Anaemic rats were treated orally with butanolic extrac

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21

Darshan, Hosmath* Ashwin Satale Aishwarya Salunkhe Pranoti Mali. "Phytochemical, Pharmacological and Antimicrobial Effects of Piper Betle Linn Extract." International Journal of Pharmaceutical Sciences 3, no. 3 (2025): 1551–61. https://doi.org/10.5281/zenodo.15038704.

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Piper betle Linn, a flowering plant species, is classified under the Piperaceae family. This climbing plant is native to various regions including India, Sri Lanka, Indonesia, and Malaysia. It features perennial, shiny leaves that are shaped like hearts. It Locally known leaves consumed its use in Ayurvedic Medicine (paan). Betel plants are grown primarily for their foliage, which is predominantly utilized as a chewing substance and breath freshener, with its main purpose being to impart flavor. Additionally, the leaves can be incorporated into culinary preparations, typically in their uncooke

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22

Renuka Jandu and Lakhwinder Kaur. "A review: Nutritional and nutraceuticals properties of betel leaves (Piper betle L.)." Global Journal of Engineering and Technology Advances 15, no. 1 (2023): 118–24. http://dx.doi.org/10.30574/gjeta.2023.15.1.0030.

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Piper betel (locally known as Paan) belongs to the Piperaceae or pepper family and many health benefits bonded with it. Betel leaves are highly nutritive and contain considerable amount of vitamins and minerals, especially calcium, iron, potassium and β-carotene. The betel leaves possess therapeutic activities such as antioxidant activity, anti-microbial, anti-ulcerogenic, anti-haemolytic activity, anti-diabetic, immune-modulatory, anti-inflammatory, gastro protective, radio protective and cytotoxicity activity. Most of the therapeutic activities of betel leaves are due to presence of antioxid

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23

Kurang, Rosalina Y. "Zone of Inhibition of Ethanol and Ethyl Acetate Extracts of Forest Betel Leaves against Escherichia Coli." Jurnal Penelitian Pendidikan IPA 9, no. 1 (2023): 154–59. http://dx.doi.org/10.29303/jppipa.v9i1.2660.

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The betel plant is one of the medicinal plants known by the common people. This plant consists of more than 1000 species. One of the species is the betel forest. The part of the betel plant that is commonly used as medicine is the leaves. This study aims to determine the phytochemical content and inhibition of Escherichia coli in the ethanol and ethyl acetate extracts of forest betel leaves (Piper aduncum L.). The method used in the antibacterial test is the good diffusion method. The research showed that ethanol extract of forest betel leaves (Piper aduncum L.) leaves contains secondary metab

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Tjitraresmi, Ami, Moelyono Moektiwardoyo, and Yasmiwar Susilawati. "Inhibition of Heme Polymerization Invitro Assay Of Extract of Sirih Leaf (Piper betle Linn.) and Sun Flower Leaves (Helianthus annuus L.)." Indonesian Journal of Pharmaceutical Science and Technology 7, no. 1 (2020): 22. http://dx.doi.org/10.24198/ijpst.v7i1.25319.

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Malaria is a disease that occurs in tropical countries like Indonesia. The incidence of malaria in the world is still quite high and the occurrence of cases of Plasmodium resistance to antimalarial drugs and the widespread of resistance have prompted researchers to look for new antimalarial drugs, especially from natural materials. Betel leaf (Piper betle Linn.) And sunflower leaf (Helianthus annuus L.) have long been used by the people of Indonesia as an antimalarial drug. The purpose of this study was to determine antimalarial activity through inhibition of heme polymerization and determine

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Renuka, Jandu, and Kaur Lakhwinder. "A review: Nutritional and nutraceuticals properties of betel leaves (Piper betle L.)." Global Journal of Engineering and Technology Advances 15, no. 1 (2023): 118–24. https://doi.org/10.5281/zenodo.7932239.

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Piper betel (locally known as <em>Paan</em>) belongs to the Piperaceae or pepper family and many health benefits bonded with it. Betel leaves are highly nutritive and contain considerable amount of vitamins and minerals, especially calcium, iron, potassium and β-carotene. The betel leaves possess therapeutic activities such as antioxidant activity, anti-microbial, anti-ulcerogenic, anti-haemolytic activity, anti-diabetic, immune-modulatory, anti-inflammatory, gastro protective, radio protective and cytotoxicity activity. Most of the therapeutic activities of betel leaves are due to p

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Irwandi, Dodi, Ai Emalia Sukmawati, and Dian Maria Ulfah. "Chemical Compound Of Liquid Smoke Derived From Leaf Of Piper betle L And Piper crocatum Ruiz & Pav." SANITAS : Jurnal Teknologi dan Seni Kesehatan 9, no. 1 (2018): 35–43. http://dx.doi.org/10.36525/sanitas.2018.5.

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Liquid smoke made from green betel leaf (Piper betle L) and red betel leaf (Piper crocatum Ruiz & Pav) has been made by pyrolysis. To determine the allegations of the chemical compounds contained in these two liquid smoke, they were tested by Gas Chromatography–Mass Spectrometry (GC-MS) method. Based on the test results it was found that there were 7 suspected compounds in the liquid smoke of green betel leaf and 30 compounds in red betel liquid smoke. The main compounds contained in the liquid smoke of green betel leaf are Isamoxole as the anti-allergic, 5,10-Diethoxy-2,3,7,8-tetrahydro-1

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Arfiyanti, Heni Nuril, Diah Titik Mutiarawati, Retno Sasongkowati, and Wisnu Isntanto. "Uji Efektivitas Ekstrak Daun Sirih Hijau (Piper Betle L), Daun Sirih Merah (Piper Crocatum) dan Daun Sirih Kuning (Piper Betle) terhadap Mortalitas Larva Nyamuk Aedes Aegypti." Malahayati Nursing Journal 4, no. 10 (2022): 2556–63. http://dx.doi.org/10.33024/mnj.v4i10.7510.

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ABSTRACT The Aedes aegypti mosquito is the main vector of DHF (Dengue Hemorrhagic Fever). In the city of Surabaya in 2019, there were 277 cases of dengue fever. Control using chemical insecticides can create resistance for larvae so that other methods can be used, namely herbal insecticides on green betel leaves, red betel leaves and yellow betel leaves which contain compounds such as essential oils, alkaloids, flavonoids, saponins and tannins which are toxic and can affect the digestive system. and nervous system in Aedes aegypti larvae. The purpose of this study was to determine the effectiv

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Yuni Widiastuti Hayoto, Aulia Debby Pelu, and Muhammad Azril Hardiman Mahulauw. "Formulasi dan Uji Stabilitas Fisik Sediaan Foot Sanitizer Tropical Spray Ekstrak Etanol Daun Sirih (Piper betle L.)." USADA NUSANTARA : Jurnal Kesehatan Tradisional 2, no. 1 (2023): 124–35. http://dx.doi.org/10.47861/usd.v2i1.617.

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Foot sanitizer spray is an inventory containing 70%-95% etanol. The content of the active materials is alcohol that has the highest strength of bacteria. One of the plants empirically utilized by society as antiseptic antismell of feet is betel leaves (Piper betle L.). This study aimed to identify the chemical content of betel leaf (Piper betle L.), made fomulation of Foot Sanitizer Spray supplies from betel leaf etanol extract (Piper betle L.), and conducted a test evaluation inventory foot sanitizer spray as well as doing irritation tests against the probandus.This type of research was exper

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Panda, Nivedita, and Arpita Panda. "Piper betel - Not Just a Mouth Freshener But Also a Miraculous Herb for Healing: A Review." Asian Journal of Biology 18, no. 2 (2023): 20–33. http://dx.doi.org/10.9734/ajob/2023/v18i2340.

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Piper betle L., often known as betel vine, is a member of the Piperaceae family and is a significant cash crop for both economic and therapeutic purposes. The betle vine is most likely from Malaysia, while it is also grown in India, Sri Lanka, Bangladesh, Myanmar, and Nepal. It is grown in the districts of Balasore, Jagatsinghpur, Puri, Khordha, and Ganjam along Odisha's coast. With tremendous potential for creating jobs and improving the socioeconomic situations of rural people in India and other Asian nations, betel vine has enormous economic, medical, and nutraceutical value. However, there

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PIN, K. Y., A. LUQMAN CHUAH, A. ABDULL RASHIH, M. A. RASADAH, C. L. LAW, and T. S. Y. CHOONG. "SOLID-LIQUID EXTRACTION OF BETEL LEAVES (PIPER BETLE L.)." Journal of Food Process Engineering 34, no. 3 (2009): 549–65. http://dx.doi.org/10.1111/j.1745-4530.2009.00395.x.

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Tran, Truc T. T., Anh T. V. Nguyen, Vinh D. H. Nguyen, Ly T. P. Trinh, and Dong N. T. Le. "Production of essential oils and sugar-rich hydrolysate from betel leaves (Piper betle)." Journal of Agriculture and Development 23, no. 1 (2024): 64–75. http://dx.doi.org/10.52997/jad.1.06.2024.

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The study was carried out to fully utilize betel leaves for the extraction of essential oils and production of sugar-rich hydrolysates from the betel leaves residues. Essential oils in the betel leaves were extracted by hydrodistillation and the betel leaves residues were enzymatically hydrolyzed to obtain sugar-rich hydrolysates. Antioxidant and antibacterial activity of the essential oils and the hydrolysates were investigated. Chemical composition analysis of the betel leaves showed that they contained 2.23% reducing sugars, 21.10% polysaccharides, 68.01 mg/g phenolics, 6.17 mg/g flavonoids

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Mastra, Nyoman. "UJI AKTIVITAS ANTIBAKTERI REBUSAN DAUN SIRIH (Piper betle Linn) TERHADAP BAKTERI Streptococcus pyogenes." Meditory : The Journal of Medical Laboratory 7, no. 1 (2019): 37–43. http://dx.doi.org/10.33992/m.v7i1.639.

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ABSTRACTBackground: Infection is a disease caused by pathogenic microbes and is very dynamic. ISPA is defined as an acute respiratory disease caused by infectious agents that were transmitted from human to human. One of the microbes that caused ISPA is Streptococcus pyogenes, which is a gram-positive bacteria and belongs to Streptococcus sp. β-hemolytic class A. Nowadays, many people are begin to use natural materials to deal with microbial infections. One of them is the betel leaf (Piper betle Linn.) Which has antibacterial and antibiotic components for the treatment of respiratory problems,

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Das, Reshma, Priyanka Pandey, Mahendra Chandravanshi, and Wasim Raja. "Piper Betel Leaf Phytochemical Study and Antimicrobial Effect against Clinical Bacterial Isolates." Journal of Advances in Pharmacy Practices 4, no. 2 (2022): 8–13. http://dx.doi.org/10.46610/japp.2022.v04i02.002.

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Herbal resources are useful for traditional medicine, folk medicine, modern medicine, nutraceuticals, dietary supplements, pharmaceutical intermediates, and chemical precursors for synthetic drugs. The antibacterial qualities of the leaves of piper betel, also known as paan, have long been employed in Indian traditional medicine. A methanol extract of Piper betel leaves was examined for its ability to inhibit the growth of Bacillus subtilis, Bacillus cereus, Bacillus frimicutes, Escherichia coli, Entrobacter, Klebsiella, and other bacteria (both gram-positive and gram-negative bacteria).The ex

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Kirti, Pawar* Dipali Suryawanshi Dhiraj Patil. "Biochemical Mechanism of Healing Activity of the Natural Phenolic, Allylpyrocatechol Against Aspirin-Induced Gastric Ulceration." International Journal of Pharmaceutical Sciences 3, no. 1 (2025): 2266–74. https://doi.org/10.5281/zenodo.14748904.

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Peptic ulcers, characterized by mucosal erosion in the stomach or duodenum, continue to pose significant health challenges worldwide. .Allylpyrocatechol, the active component obtained from ethanol extract of leaves of Piper betle. The study investigates the healing properties of a specific compound, allylpyrocatechol, which is derived from Piper betel. This compound is evaluated for its effectiveness against stomach ulceration induced by aspirin , a nonsteroidal anti-inflammatory drug (NSAID) known to cause gastric ulcers . allyl pyrocatechol (APC), the major antioxidant constituent of Piper b

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Elfahmi, Elfahmi, Komar Ruslan Wirasutisna, and Heipy Ketrin Desyane. "Isolasi Senyawa Aktif Lignan dari Buah Lada Hitam (Piper nigrum L.) dan Daun Sirih (Piper betle L.)." Acta Pharmaceutica Indonesia 37, no. 1 (2012): 14–17. http://dx.doi.org/10.5614/api.v37i1.4032.

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Buah lada hitam (Piper nigrum L.) dan daun sirih (Piper betle L.) telah banyak digunakan secara tradisional untuk mengobati beberapa jenis penyakit. Beberapa senyawa metabolit sekunder yang terkandung pada kedua tanaman tersebut diduga bertanggungjawab terhadap efek farmakologi, salah satu golongan metabolit sekunder tersebut adalah lignan. Penelitian ini bertujuan untuk mengisolasi senyawa lignan dari buah lada dan daun sirih. Serbuk simplisia dari daun sirih dan buah lada hitam diekstraksi dengan ekstraksi sinambung menggunakan pelarut metanol. Ekstrak difraksinasi dengan ekstraksi cair-cair

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Julianto, Eko, Made Suandika, Ayu Tri Agustin, Julianus Julianus, and Jepri Riranto. "Efficacy of wound cleanser 25% based on indonesian medicine plants on chronic wound healing." Riset Informasi Kesehatan 12, no. 1 (2023): 73. http://dx.doi.org/10.30644/rik.v12i1.737.

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 ABSTRACT Background: Chronic wounds are a challenge for wound care professionals and a global economic burden that has increased morbidity and mortality in patients worldwide. Purpose: This study aims to determine the efficacy of wound cleanser with guava leaf extract (Psidium guajava Linn) and betel leaf extract (Piper betle L) 25% on the inhibition of bacterial growth in chronic wounds. Methods: The research conducted was laboratory experimental in nature. Guava leaf extract (Psidium guajava Linn) and betel leaf extract (Piper betle L) were formulated in the form of

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Pahlevi, Resa, Harapin Hafid, and Amiluddin Indi. "BOBOT AKHIR PERSENTASE KARKAS DAN LEMAK ABDOMINAL AYAM BROILER DENGAN PEMBERIAN EKSTRAK DAUN SIRIH (Piper betle L.) DALAM AIR MINUM." Jurnal Ilmu dan Teknologi Peternakan Tropis 2, no. 3 (2018): 1. http://dx.doi.org/10.33772/jitro.v2i3.3801.

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This study aims to know the effect of (Piper betle L.) leaves extract addition in drinking water on carcass percentage and abdominal fat of broiler chicken. Experimental material was used to this study were eighty broiler chicken SR-707. Broiler chicken was divided into twenty pen with five treatments and four replications and each pen was filled with four broiler chickens. The treatments were P1 = drinking water without betel leaves extract, P2 = drinking water + 0,5% extract of betel leaves, P3 = drinking water + 1% extract of betel leaves, P4 drinking water + 1,5% betel leaves extract, and

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Haryanto Haryanto and Febriyanti Aswinda. "Daun Sirih Hutan (Piper Aduncum) Terhadap Penghambatan Transport Glukosa Menggunakan Ileum Tikus Putih (Rattus Novergicus) dengan Metode Infusa." OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan 3, no. 2 (2025): 188–96. https://doi.org/10.61132/obat.v3i2.1161.

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Diabetes mellitus is one of the chronic diseases whose prevalence is increasing worldwide. This disease is characterized by high blood glucose levels due to impaired insulin production or function, the hormone that regulates blood sugar levels. This study aims to examine the effect of wild betel leaf extract (Piper aduncum) on the inhibition of glucose transport using the ileum of white rats (Rattus norvegicus) with the infusion method. This research is a pre-experimental study with a posttest-only control design using white rats and wild betel leaves. The study demonstrates that wild betel le

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Rahmatika, Resty. "The Existence Of the Betel Leaf (Piper betle L.) is in the Tasawuf Prespective." Journal Intellectual Sufism Research (JISR) 2, no. 1 (2019): 42–46. http://dx.doi.org/10.52032/jisr.v2i1.46.

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Plants are one of the richest natural resources in Indonesia and contain active chemicals.These plants have the potential to become raw materials for traditional medicine. One of them isbetel plant. The use of Betel leaves, especially in Java, is generally accompanied by specialconditions or criteria, namely: betel leaf which 'meets ros-e'. 'Ros' comes from the Javanese languagewhich means vein, in this case it is a vein of leaves. 'Temu' comes from the Javanese language whichmeans to meet, meet. Betel rose meeting is betel which leaves veins (lateral nerves) meet theposition of the segment; s

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Destiana, Ika, Nurhasanah Nurhasanah, and Ria Yulianti Triwahyuningsih. "Benefits of Betel Leaves as a Medicine for Postpartum Perineal Wounds." Jurnal Medisci 2, no. 2 (2024): 117–29. http://dx.doi.org/10.62885/medisci.v2i2.496.

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Indonesia is a country rich in natural materials for human health. One of them is red betel. This research was conducted to formulate red betel as a medicine for perineal wounds in mothers after childbirth. Making wound medicine by boiling. Boil 4-5 sheets or 9-11 grams (Piper Crocatum) that have been washed thoroughly, put 500 ml of water into a pot made of clay so as not to damage the substance content of red betel leaf (Piper Crocatum). Wait for it to boil for 15 minutes. Let the boiled water cool for 30 minutes, then strain the water and put the filtered result in the sterile bottle that h

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Pin, K. Y., T. G. Chuah, A. Abdull Rashih, C. L. Law, M. A. Rasadah, and T. S. Y. Choong. "Drying of Betel Leaves (Piper betleL.): Quality and Drying Kinetics." Drying Technology 27, no. 1 (2009): 149–55. http://dx.doi.org/10.1080/07373930802566077.

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T, SIVAKUMAR, and YESHWANTH H. M. "Helopeltis theivora (Heteroptera, Miridae) as a pest of betel vine (Piper betle)." Indian Journal of Agricultural Sciences 90, no. 2 (2020): 242–43. http://dx.doi.org/10.56093/ijas.v90i2.99053.

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Tea mosquito bug (TMB), Helopeltis theivora Waterhouse (Heteroptera, Miridae) has been recorded for the first time from Kerala, India, as a pest of betel vine (Piper betle L.). Nymphs and adults feed on the tender leaves making it unfit for consumption and sale. Angular water-soaked patches which later appear like shot holes were the symptoms of infestation. Neem oil soap emulsion (0.2%) was effective against the pest. The infested plot was not near tea or cashew plantations, which ruled out the possibility of opportunistic incidence of H. theivora on P. betle. Hence, it is evident that H. the

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Hasibuan, Ali Ahmatul Umri, Grace Amelia Br Tarigan, Khadra Ulfah Rambe, Sisilia Anabina Tarigan, and Endang Sulistyarini Gultom. "Uji Aktivitas Antibakteri Dari Ekstrak Daun Sirih Terhadap Bakteri Bacillus cereus." Jurnal Biologi dan Pembelajarannya (JB&P) 11, no. 1 (2024): 47–54. https://doi.org/10.29407/jbp.v11i1.21662.

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This study elucidates the role of secondary metabolites in green betel leaves (Piper betle) as antibacterial agents against Bacillus cereus, a bacterium causing various foodborne illnesses in humans. The experimental research was conducted at the Biology Laboratory, Faculty of Mathematics and Natural Sciences, Universitas Negeri Medan, utilizing Bacillus cereus bacterial isolates and extracting betel leaves using water. The measurement of inhibition zones was performed to evaluate the antibacterial activity of the betel leaf extract. The research results indicate the presence of an inhibition

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Purwanti, Rosa. "THE EFFECTIVENESS OF THE DECOCTION OF RED BETEL LEAVES (PIPER CROCANTUM) AGAINST THE REDUCED SYMPTOMS OF FLUOR ALBUS IN ADOLESCENT GIRLS." Journal of Vocational Health Studies 5, no. 3 (2022): 146. http://dx.doi.org/10.20473/jvhs.v5.i3.2022.146-151.

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Background: Fluor albus is excessive fluid from vagina that is not menstruation. To reduce the symptoms of fluor albus, non-pharmacological treatment from the decoction water of red betel leaves (Piper crocantum) was used in the present study. These red betel leaves (Piper crocantum) contain alkaloids that the green betel leaves do not have, and the alkaloids play a role as an antimicrobial agent. Besides, the red betel leaves have antiseptic power that is twice higher than the green betel leaves. The red betel leaves (Piper crocantum) also contain carvakrol which is anti-fungal and disinfecta

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Sharma, Pooja, Ritu Rani, Ajeet Pal Singh, and Amar Pal Singh. "Restoration of Memory Potential by Piper betel Leaves Extract in High-Fat Diet (HFD)-Induced Dementia in Mice." Journal of Drug Delivery and Therapeutics 15, no. 1 (2025): 19–27. https://doi.org/10.22270/jddt.v15i1.6943.

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The present study has been designed to evaluate the effect of ethanolic extract of leaves of Piper betel in high fat diet (HFD) induced dementia and memory restoration effect in Albino mice by various parameters like Morris water maze (MWM) test, Elevated Plus Maze etc. and Estimation of serum total cholesterol using commercially available kit. Dementia is a syndrome in which the deterioration of cognitive functions occurs. The results of this study indicate that the administration of a high-fat diet to the Swiss mice produces a severe deterioration of spatial memory as determined by the Morri

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Tejaswini, Mare* Swapnali Karle Jatin Kudnar. "Formulation and Evaluation of Antimicrobial Herbal Hand Wash Using Betal Leaf." International Journal of Pharmaceutical Sciences 3, no. 4 (2025): 2047–56. https://doi.org/10.5281/zenodo.15231956.

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In the present study ethanolic extracts of leaves of Piper betel were screened for antibacterial properties against pathogenic bacteria namely Pseudomonas aeruginosa and Staphylococcus aureus. The extract were effective against the used pathogens. Ethanolic extracts. Showed a maximum zone of inhibition 14mm against Staphylococcus aureus and 16mm against Pseudomonas aeruginosa.  The Increasing prevalence of antimicrobial resistance and the adverse effects of synthetic chemicals have driven the need for natural alternatives in personal hygiene products. This research explores the developmen

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Hamdani, Hamdani, Anindita Septiarini, Novianti Puspitasari, Andi Tejawati, and Faza Alameka. "The color features and k-nearest neighbor algorithm for classifying betel leaf image." IAES International Journal of Robotics and Automation (IJRA) 13, no. 3 (2024): 330. http://dx.doi.org/10.11591/ijra.v13i3.pp330-337.

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Piper betle L. (betel) is a species that belongs to the genus Piper and is a type of medicinal plant that is quite well known to the general population. The varieties of the leaf color may distinguish are red, green, and black betel. However, consumers still need assistance determining the differences between the many types of betel leaf. Therefore, using image processing techniques, this research contributes to building a classification method for distinguishing betel leaves based on color attributes. This approach anoints for the region of interest detection, feature extraction, and classifi

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Hamdani, Hamdani, Anindita Septiarini, Novianti Puspitasari, Andi Tejawati, and Faza Alameka. "The color features and k-nearest neighbor algorithm for classifying betel leaf image." IAES International Journal of Robotics and Automation 13, no. 3 (2024): 330–37. https://doi.org/10.11591/ijra.v13i3.pp330-337.

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Piper betle L. (betel) is a species that belongs to the genus Piper and is a type of medicinal plant that is quite well known to the general population. The varieties of the leaf color may distinguish are red, green, and black betel. However, consumers still need assistance determining the differences between the many types of betel leaf. Therefore, using image processing techniques, this research contributes to building a classification method for distinguishing betel leaves based on color attributes. This approach anoints for the region of interest detection, feature extraction, and classifi

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Suri, Melani Antika, Zikra Azizah, and Ridho Asra. "A Review: Traditional Use, Phytochemical and Pharmacological Review of Red Betel Leaves (Piper Crocatum Ruiz & Pav)." Asian Journal of Pharmaceutical Research and Development 9, no. 1 (2021): 159–63. http://dx.doi.org/10.22270/ajprd.v9i1.926.

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Red betel leaf (Piper crocatum Ruiz & Pav) is a plant that grows in tropical areas and was previously known as an ornamental plant, but was later used as a medicinal plant. The use of red betel leaf (Piper crocatum Ruiz & Pav) is traditionally beneficial in curing diseases such as thrush and toothache. Meanwhile, red betel leaf decoction, which is antiseptic, can act as a mouthwash, prevent bad breath and eliminate body odor. From chromatography, it is known that red betel leaves contain flavonoids, polyphenolic compounds, tannins, and essential oils. In the use of red betel leaves, it

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Sarjani, Tri Mustika, Mawardi Mawardi, Ekariana S. Pandia, and Devi Wulandari. "IDENTIFIKASI MORFOLOGI DAN ANATOMI TIPE STOMATA FAMILI Piperaceae DI KOTA LANGSA." Jurnal IPA & Pembelajaran IPA 1, no. 2 (2017): 182–91. http://dx.doi.org/10.24815/jipi.v1i2.9693.

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Abstrak. Penelitian bertujuan untuk mengetahui morfologi dan anatomi tipe stomata dari famili piperaceae yang terdapat di Kota Langsa. Penelitian diharapkan dapat memberikan informasi kepada masyarakat dan mahasiswa tentang morfologi dan anatomi tipe stomata tanaman dari famili piperaceae. Hasil penelitian dapat dijadikan sebagai data awal tentang morfologi dan anatomi tumbuhan dari famili piperaceae yang terdapat di Kota Langsa. Metode yang digunakan diskriptif kualitatif untuk menggambarkan dan menginterpretasi tipe stomata pada daun famili piperaceae. Hasil penelitian tumbuhan famili pipera

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