Academic literature on the topic 'Piperazinediones'

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Journal articles on the topic "Piperazinediones"

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Fukuyama, Tohru, R. Keith Frank, and Alison A. Laird. "Synthesis of unsymmetrically substituted 2,5-piperazinediones: regioselective alkylation of piperazinedione derivatives." Tetrahedron Letters 26, no. 25 (1985): 2955–58. http://dx.doi.org/10.1016/s0040-4039(00)98590-3.

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Basiuk, Vladimir A., and Taras Yu Gromovoy. "Free Energies of Adsorption of Dipeptides and 2,5-Piperazinediones on Silica from Neutral Aqueous Solutions as Estimated from High-Performance Liquid-Chromatographic Retention Data." Collection of Czechoslovak Chemical Communications 59, no. 8 (1994): 1721–28. http://dx.doi.org/10.1135/cccc19941721.

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The equilibrium constants (K) and free energies (-∆G) of adsorption of dipeptides and their cyclic derivatives, 2,5-piperazinediones, on silica from neutral aqueous solutions were calculated from their HPLC retention data on a silica gel column. For the majority of the dipeptides -∆G values were negative, ranging from -1 170 to 430 J mol-1, and K < 1, thus indicating a very weak adsorption. The 2,5-piperazinediones under study exhibited higher adsorbabilities (-∆G -1 070 + 3 030 J mol-1, K > 1) as compared to the respective dipeptides. The effect of the α-substituent structure on the ads
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Soukara, Stella, and Bernhard Wünsch. "Regioselective thionation of bicyclic piperazinediones." Tetrahedron 57, no. 20 (2001): 4359–63. http://dx.doi.org/10.1016/s0040-4020(01)00324-6.

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Sun, Chung-Ming, K. Swamy, Mei-Jung Lin, Wen-Ben Yeh, Fred Chen, and Wei-Hong Tseng. "Traceless Liquid Phase Synthesis of Piperazinediones." Combinatorial Chemistry & High Throughput Screening 6, no. 2 (2003): 133–37. http://dx.doi.org/10.2174/1386207033329733.

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Soukara, Stella, and Bernhard Wuensch. "ChemInform Abstract: Regioselective Thionation of Bicyclic Piperazinediones." ChemInform 32, no. 34 (2010): no. http://dx.doi.org/10.1002/chin.200134069.

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Kasafírek, Evžen, Jaroslav Moural, Jarmila Vinšová, Antonín Šturc, and Jan Taimr. "Cyclic Dipeptides with 1-Aminocyclopropane-1-carboxylic Acid." Collection of Czechoslovak Chemical Communications 62, no. 6 (1997): 941–47. http://dx.doi.org/10.1135/cccc19970941.

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Cyclic dipeptides of the formula cyclo(-Acc-X-), where Acc = 1-aminocyclopropane-1-carboxylic acid, X = Gly, Ala, Val, Leu, Phe or Tyr, were synthesized. The prepared 2,5-piperazinediones showed no proliferative or antiproliferative activity on normal human embryo cells as well as on HL60 leukemia cells. Results of trace memory assays in mice were negative.
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Williams, Robert M., Robert W. Armstrong, Lynn K. Maruyama, Jen Sen Dung, and Oren P. Anderson. "Divergent, generalized synthesis of unsymmetrically substituted 2,5-piperazinediones." Journal of the American Chemical Society 107, no. 11 (1985): 3246–53. http://dx.doi.org/10.1021/ja00297a034.

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Huck, Lena, Juan F. González, Elena de la Cuesta та J. Carlos Menéndez. "Three-component synthesis of highly functionalized aziridines containing a peptide side chain and their one-step transformation into β-functionalized α-ketoamides". Beilstein Journal of Organic Chemistry 12 (8 серпня 2016): 1772–77. http://dx.doi.org/10.3762/bjoc.12.166.

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A sequential three-component process is described, starting from 3-arylmethylene-2,5-piperazinediones and involving a one-pot sequence of reactions achieving regioselective opening of the 2,5-diketopiperazine ring and diastereoselective generation of an aziridine ring. This method allows the preparation of N-unprotected, trisubstituted aziridines bearing a peptide side chain under mild conditions. Their transformation into β-trifluoroacetamido-α-ketoamide and α,β-diketoamide frameworks was also achieved in a single step.
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Kumar, Devendra, Sukesh K. Gupta, Ankit Ganeshpurkar, et al. "Biological profiling of piperazinediones for the management of anxiety." Pharmacology Biochemistry and Behavior 176 (January 2019): 63–71. http://dx.doi.org/10.1016/j.pbb.2018.11.009.

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Lovelette, C. A., and K. Geagan. "A conveneint synthesis of 1-substituted-2,5(4H)-piperazinediones." Journal of Heterocyclic Chemistry 23, no. 1 (1986): 229–31. http://dx.doi.org/10.1002/jhet.5570230147.

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Dissertations / Theses on the topic "Piperazinediones"

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Khanal, Pitambar. "Crystal Engineering with Piperazinediones." Diss., The University of Arizona, 2016. http://hdl.handle.net/10150/612051.

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Non covalent interactions are valuable tools for crystal engineering. Hydrogen bonding often plays a central role for molecular association among possible non covalent interactions. Together with hydrogen bonding, arene-arene interactions and van der Waals interactions can control crystal assembly. Understanding non covalent interactions permits the design of molecules whose functionalities can interact non covalently so that molecules will pack in a predicted fashion. For two decades Prof. Mash's group has been studying crystal packing based on a piperazinedione core scaffold which can have t
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Badran, Terry William. "Selective functionalization and elaboration of 2,5-piperazinediones /." Title page, contents and abstract only, 1991. http://web4.library.adelaide.edu.au/theses/09PH/09phb138.pdf.

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Book chapters on the topic "Piperazinediones"

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Albericio, Fernando, Montse del Fresno, Ariadna Frieden, et al. "Backbone amide linker (BAL) for solid-phase synthesis of 2,5-piperazinediones (DKP), useful scaffolds for combinatorial chemistry." In Peptides Frontiers of Peptide Science. Springer Netherlands, 2002. http://dx.doi.org/10.1007/0-306-46862-x_9.

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Demaison, J. "444 C4H6N2O2 2,5-Piperazinedione." In Asymmetric Top Molecules. Part 2. Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-10400-8_192.

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Conference papers on the topic "Piperazinediones"

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Menéndez, J., Alberto López-Cobeñas, Pilar Cledera, et al. "Solvent-Free, Efficient Synthesis of 2,5-piperazinediones from BOC-Protected Dipeptides under Microwave Irradiation." In The 8th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2004. http://dx.doi.org/10.3390/ecsoc-8-01985.

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Chen, Mei-Chuan, Hui-Po Wang, Chun-Han Chen, Yi-Nan Liu, Shiow-Ling Pan, and Che-Ming Teng. "Abstract 4497: TW01001, a novel piperazinedione compound, induces mitotic arrest and autophagy in non-small cell lung cancer A549 cells." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-4497.

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