Dissertations / Theses on the topic 'Plate radiation'
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Chu, Pearl. "Nonaxisymmetric radiation patterns of a vibrating elastic plate." Thesis, Georgia Institute of Technology, 1990. http://hdl.handle.net/1853/17902.
Full textSors, Thomas Christopher. "Active structural acoustic control of sound transmission through a plate." Thesis, University of Southampton, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.326822.
Full textWachsmuth, Matthew George. "Measurement and Characterization of Terahertz Radiation Propagating Through a Parallel Plate Waveguide." PDXScholar, 2011. https://pdxscholar.library.pdx.edu/open_access_etds/317.
Full textRew, Gayle Astrid Adele. "Studies in zone plate encoded holography with high energy gamma rays." Thesis, University of Birmingham, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.366166.
Full textAbrahamson, Stuart M. "In-situ measurement of total dose radiation effects on parallel plate MOS capacitors using the NPS linear accelerator." Thesis, Monterey, Calif. : Springfield, Va. : Naval Postgraduate School ; Available from National Technical Information Service, 1995. http://handle.dtic.mil/100.2/ADA306694.
Full text"December 1995." Thesis advisor(s): Sherif Michael, Oscar Biblarz. Includes bibliographical references. Also available online. Mode of access: World Wide Web.
Salem, Said Abdel-Halim Saber. "Large Eddy Simulation of Shear-Free Interaction of Homogeneous Turbulence with a Flat-Plate Cascade." Diss., Virginia Tech, 2007. http://hdl.handle.net/10919/28520.
Full textPh. D.
Jones, Cameron Bennion. "Development and Validation of a Vibration-Based Sound Power Measurement Method." BYU ScholarsArchive, 2019. https://scholarsarchive.byu.edu/etd/9260.
Full textJohansson, Helena. "Nocturnal cooling : Study of heat transfer from a flat-plate solar collector." Thesis, Karlstad University, Faculty of Technology and Science, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:kau:diva-1523.
Full textThis thesis investigates the possibility of using an unglazed flat-plate solar collector as a cooling radiator. The solar collector will be connected to the condenser of a heat pump and used as cooler during nighttime. Daytime the solar collector will be connected to the evaporator of the heat pump and used as heat source. The two widely differing fields of application make special demands on the solar collector. The task is given by the heat pump manufacturer Thermia and the main objective is to find out whether a solar collector should be used as a cooler or not. The performance of the solar collector under varying environmental conditions is investigated using COMSOL Multiphysics 3.3. Only the cooling properties are investigated here. The performance of the solar collector as a heat exchanger is estimated using the effectiveness-NTU method, and the solar collector is found to be a good heat exchanger at low wind speeds. The heat transfer coefficients of the convection and radiation are determined for varying temperature and wind speeds. The convective heat transfer coefficient is lowered by tubes above the absorber plate and for a high convective heat transfer rate the solar collector surface should be smooth. For a high radiative heat transfer rate the surface needs to have a high emissivity. The cooling rate is higher from a warm surface than from a cold and since no temperature change of the heat carrier is necessary the solar collector should be kept at a high temperature. To increase the cooling rate alterations need to be made to the solar collector that makes its heating performance deteriorate. A solar collector that can be used for cooling is not an efficient solar collector.
Hendricks, Daniel R. "An Experimental Analysis of the Weighted Sum of Spatial Gradients Minimization Quantity in Active Structural Acoustic Control of Vibrating Plates." BYU ScholarsArchive, 2013. https://scholarsarchive.byu.edu/etd/3827.
Full textRousset, Philippe. "Etude expérimentale et théorique du fonctionnement du détecteur gazeux à lame en mode proportionnel." Grenoble 1, 1986. http://www.theses.fr/1986GRE10076.
Full textPutra, Azma. "Sound radiation from perforated plates." Thesis, University of Southampton, 2008. https://eprints.soton.ac.uk/63161/.
Full textSolomon, Brad K. "Methods for Identifying Acoustic Emissions From the Front Face of a Small Piezoelectric Blower." BYU ScholarsArchive, 2012. https://scholarsarchive.byu.edu/etd/3542.
Full textWang, Duo. "Analyse et conception de répéteurs passifs plans à rayonnement quasi-latéral pour communications «indoor» à 60GHz." Thesis, Rennes, INSA, 2015. http://www.theses.fr/2015ISAR0011/document.
Full textThe fast development of information and consumer electronics industries creates a pressing demand for high-speed indoor communications. Traditional communication protocols are unable to support such high transmission rate, and there are no radio bands available at lower frequency. As an alternative, 60GHz communications have sparked great attention, since it enables a maximum data transmission rate more than 5Gbit/s based on its wide unlicensed bandwidth. However, practical indoor environment is usually complicated (e.g. walls, corridors, stairs, etc.), thus the non-line-of-sight (NLOS) areas cannot be covered due to the significant attenuation. Considering the requirements for signal recovery in the NLOS environment, a planar passive repeater with endfire radiation and high directivity, low profile and low cost is investigated and designed in this thesis. Based on array theory, a periodic structure for the foreseen printed repeater is derived out. It involves two reflector elements (in the spacing of 2) to provide 0° and 180°reflection phases respectively. In order to construct a proper reflector element, four topologies are proposed and analyzed. In the first part of the study, DRA (Dielectric Resonator Antenna) technology is the main focus. Two different topologies are investigated and compared, including notched DRA and DRA coupled to phase-shift stub. Different modeling strategies are also studied using either a single cell, a couple of cells with opposite phases or a small array. For each topology, a preliminary 6×6 array is simulated. Optimization at the array level is emphasized through the whole thesis. In the second part, investigations are taken on a rectangular dielectric filled waveguide element. Parametric analyses are carried out and possible fabrication technologies are discussed. Once again, a preliminary 6×6 array is designed and optimized to validate the feasibility of such a structure. In the third part, a parallel-plate groove structure is analyzed. It evolves from the rectangular waveguide, and enjoys more simplification. Further work is taken to explore the arrays’ bandwidth, oblique incidence performance and maximum radiation direction. Detailed theoretical analysis based on the simulation results are demonstrated in the end. Finally, an array based on the groove elements is fabricated in the size of 200mm×200mm. Practical measurements for 60GHz communications in NLOS environment are designed to test the array’s performance. Analyses on the experiment results are given
Gu, Yi. "Active control of sound radiation from fluid loaded plates." Diss., Virginia Tech, 1992. http://hdl.handle.net/10919/39888.
Full textPh. D.
Llewellyn, Smith Stefan Gregory. "Vortices and Rossby-wave radiation on the beta-plane." Thesis, University of Cambridge, 1996. https://www.repository.cam.ac.uk/handle/1810/244817.
Full textMeulle, Aline. "Place des adipocytes dans la réponse tissulaire aux radiations ionisantes." Toulouse 3, 2008. http://thesesups.ups-tlse.fr/333/.
Full textRadiotherapy is a major therapeutic strategy in the treatment of many human tumors becase the exposure to ionizing radiation (IR) induces DNA damage and among them DNA double strand breaks (DSBs). However, cancer is a tissue-based disease in which malignant cells interact dynamically with multiple normal cell or stroma, and to the response to IR, emerging studies suggest that the irradiated stroma can influence the sensibility of cancer cell. Stroma was composed by differents types of cell, and adipocytes cells are excellent candidat because they are highly represented in breast tumor stroma and are able to secrete many factors. So the goal of our project was to investigate if adipocyte can influence the tissue response to IR. As a first step, we have demonstrated that the ability to repair DSBs is increased during adipocyte differentiation, that can explain by the increase of expression and activity of a key protei of DSB repair, DNA-PKcs. This result are observed during human and mrin adipogenesis. Moreover, we are observed that adipocyte are radioresistan cell and this ability to resist to genotoxic stress supports the idea that adipocytes might participate to radioresistance at a tissue level. In fact we demonstrated, in a 2D co-culture model that adipocytes protect breast cancer cell from clonogenic cell death in a manner that is dependent of secreted soluble factors. Accordingly, it would be of interest to evaluate the paracrine role of adipocytes within the context of obesity that has been recently established a negative prognostic factor even for localized breast tumors
Stewart, Kristin J. "Accurate radiation dosimetry using liquid- or air-filled plane-parallel ionization chambers." Thesis, McGill University, 2001. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=29576.
Full textAli, Syed Mahmood. "Plane wave scattering from circular and hollow circular slit cylinders using the On Surface Radiation Condition (OSRC) approach." Thesis, Monterey, California : Naval Postgraduate School, 1990. http://handle.dtic.mil/100.2/ADA243793.
Full textThesis Advisor(s): Janaswamy, R. Second Reader: Adler, Richard W. "December 1990." Description based on title screen as viewed on March 30, 2010. DTIC Descriptor(s): Linear systems, thickness, scattering, polarization, distribution, formulations, integrals, shape, structures, theses, electromagnetic wave propagation, reflection, surfaces, surface properties, wave propagation, cylindrical bodies, width, integral equations, frequency domain, plane waves, circular, truncation, concave bodies, convex bodies, radiation DTIC Identifier(s): Radar reflections, hollow cylinders, slit cylinders, OSRC (on surface radiation condition). Author(s) subject terms: Surface radiation conditions; transverse electric; circular cylinders; hollow cylinder slit cylinders Includes bibliographical references (p. 68-69 ). Also available in print.
Hoppe, Stefan. "Emitters of VHE gamma-radiation as revealed by the H.E.S.S. galactic plane survey." [S.l. : s.n.], 2008. http://nbn-resolving.de/urn:nbn:de:bsz:16-opus-88939.
Full textWang, Bor-Tsuen. "Active control of sound transmission/radiation from elastic plates using multiple piezoelectric actuators." Diss., Virginia Tech, 1991. http://hdl.handle.net/10919/39956.
Full textChin, Erika. "Calculation of water and graphite perturbation correction factors for the NACP-02 plane-parallel ionization chamber in high-energy electron beams." Thesis, McGill University, 2008. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=18699.
Full textPour les faisceaux d'électrons de haute énergie (MV), les protocoles de dosimétrie actuels supposent que les chambres d'ionisation à plaques parallèles ont des facteurs de correction de perturbation électronique égaux à l'unité. Plusieurs articles d'autres auteurs ont démontré le contraire. Le National Physical Laboratory (NPL), Teddington Royaume-Uni, possède un service d'étalonnage qui requiert de savoir les facteurs de perturbation de l'eau par rapport au graphite pour leur chambre NACP-02. A l'aide du code Monte Carlo EGSnrcMP, les facteurs de correction de perturbation à profondeur zref dans le graphite ont été calculés pour le linac Radiation Dynamics du NPL à des énergies de 4-19 MeV. Ces résultats, combinés à ceux dans l'eau calculés par Zakikhani (2006), ont montré que seulement les facteurs de perturbation de l'eau par rapport au graphite des faisceaux de 4 MeV et 12 MeV, à 1,0080 ± 0,27 % et 1,0071 ± 0,28 % respectivement, étaient significativement différents de l'unité. Les facteurs de correction de perturbation dans l'eau et dans le graphite ont aussi été étudiés pour les linacs cliniques de Varian à 4-18 MeV. D'importants problèmes ont alors été soulevés, notamment des différences dans les résultats causés par des énergies de coupure de 1 keV par rapport à 10 keV ainsi que la question de savoir si la profondeur du point de mesure devrait prendre en compte l'épaisseur effective de la fenêtre d'entrée. Ces problèmes requièrent davantage d'études.
Morris, Russell A. "Optimal state estimation for the optimal control of far-field acoustic radiation pressure from submerged plates." Thesis, This resource online, 1992. http://scholar.lib.vt.edu/theses/available/etd-06232009-063036/.
Full textLee, Hyeongill. "Modal acoustic radiation characteristics of a thick annular disk." Connect to this title online, 2003. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1053709926.
Full textTitle from first page of PDF file. Document formatted into pages; contains xxix, 163 p. : ill. (some col.). Advisor: Rajendra Singh, Department of Mechanical Engineering. Includes bibliographical references (p. 160-163).
Bernier, Marie-Odile. "Mise en place d'une cohorte d'enfants exposés au scanner et analyse du risque de cancer radio-induit." Thesis, Paris 6, 2016. http://www.theses.fr/2016PA066744/document.
Full textMedical diagnostic exposure to ionizing radiation represents about 40% of the total annual radiation exposure in France. The CT scans, which represent only 5% of the total number of X-rays examinations, account for half of the total collective dose associated with medical diagnostic exposure. However, its use continues to grow, including in children, for whom the radio sensitivity is known to be greater than in adults. Several recent studies support an increased risk of leukemia and brain tumors after exposure to CT scan in childhood. A national multicenter cohort was set up at the IRSN since 2009 including 108 137 children subjected to at least one CT scans before the age of 10 during the 2000 to 2013 period in 23 French University hospital’s pediatric radiology departments. Children's exposure was assessed based on radiological protocols. It was observed high variability of doses according to the participant departments, reflecting the need for protocol optimization. Moreover, children with predisposing factor for studied cancers represented 3% of the study population, a percentage well above that observed in the general population. The linkage of the cohort with the National Register of pediatric cancers identified 106 incident cases of cancer in the cohort, 22 brain tumors and 17 leukemias. For children without predisposing factor, it was observed a non-significant excess risk of cancer according to the received dose, similar to that observed for the whole study population. For children with predisposing factor to cancer, the risk decreased without reaching significance, possibly linked to earlier non-cancer mortality in this group and then to a lower risk to develop later radiation induced cancer. The European project EPI-CT, which includes 9 national cohorts (including the French cohort), will include more than one million children and then will bring further results on this topic
Matsuda, Yoshinobu. "Polar-Plane-Free Faceted InGaN-LEDs toward Highly Radiative Polychromatic Emitters." Doctoral thesis, Kyoto University, 2020. http://hdl.handle.net/2433/253285.
Full text0048
新制・課程博士
博士(工学)
甲第22449号
工博第4710号
新制||工||1736(附属図書館)
京都大学大学院工学研究科電子工学専攻
(主査)教授 川上 養一, 教授 野田 進, 教授 山田 啓文
学位規則第4条第1項該当
Doctor of Philosophy (Engineering)
Kyoto University
DFAM
Kitts, Zachary Todd. "An Analytical Study of the Weak Radiating Cell as a Passive Low Frequency Noise Control Device." Thesis, Virginia Tech, 2000. http://hdl.handle.net/10919/35507.
Full textMaster of Science
Alves, Marta Isabel Rocha. "Diffuse radio recombination line emission on the galactic plane." Thesis, University of Manchester, 2011. https://www.research.manchester.ac.uk/portal/en/theses/diffuse-radio-recombination-line-emission-on-the-galactic-plane(54655adf-a0da-4f27-86fb-0d8ae43e1e80).html.
Full textNONATO, FERNANDA B. C. "Projeto, construção e caracterização de sistemas de referência para feixes de elétrons de aceleradores clínicos." reponame:Repositório Institucional do IPEN, 2014. http://repositorio.ipen.br:8080/xmlui/handle/123456789/23232.
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Tese (Doutorado em Tecnologia Nuclear)
IPEN/T
Instituto de Pesquisas Energeticas e Nucleares - IPEN-CNEN/SP
Zakikhani, Ramtin. "Calculated perturbation factors for the NACP-02 plane-parallel ionization chamber irradiated in water by megavoltage electron beams." Thesis, McGill University, 2006. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=99213.
Full textMehrtash, Mehdi. "Numerical Investigation Of Natural Convection From Plate Finned Heat Sinks." Master's thesis, METU, 2011. http://etd.lib.metu.edu.tr/upload/12613530/index.pdf.
Full textField, Parker Lawrence. "Comparison of RANS and Potential Flow Force Computations for the ONR Tumblehome Hullfrom in Vertical Plane Radiation and Diffraction Problems." Thesis, Virginia Tech, 2013. http://hdl.handle.net/10919/23123.
Full textMaster of Science
Pelteku, Altin E. "Development of an electromagnetic glottal waveform sensor for applications in high acoustic noise environments." Link to electronic thesis, 2004. http://www.wpi.edu/Pubs/ETD/Available/etd-0114104-142855/.
Full textKeywords: basis functions; perfectly matched layers; PML; neck model; parallel plate resonator; finite element; circulator; glottal waveform; multi-transmission line; dielectric properties of human tissues; radiation currents; weighted residuals; non-acoustic sensor. Includes bibliographical references (p. 104-107).
Scheibe, Oskar. "Modelling of Heat Transfer for Convection-boosted Flat Vertical Radiator Surfaces : An investigation of how heat transfer is influenced by radiator height and freestream air velocity." Thesis, KTH, Strömnings- och klimatteknik, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-220138.
Full textEmonet, Piccardi Nathalie. "Place des thiols dans la photoprotection." Université Joseph Fourier (Grenoble), 1998. http://www.theses.fr/1998GRE10246.
Full textNontakaew, Udomkiat. "Etude théorique et expérimentale du problème de radiation d'ondes par une plaque plane en oscillations forcées avec vitesse d'avance." Poitiers, 1996. http://www.theses.fr/1996POIT2313.
Full textWhelan, Jedidiah J. "Diverse Polarization Extension to MUSIC Applied to a Circular Array of H-Plane Horns." University of Dayton / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=dayton1291326302.
Full textGonneau, Vincent. "Modélisation du transfert thermique par marcheurs browniens dans des milieux hétérogènes." Thesis, université Paris-Saclay, 2020. http://www.theses.fr/2020UPAST022.
Full textThis work deals with the modeling of transient conduction heat transfer by brownian walkers within a heterogenous medium. The medium is described by a 3D voxelised structure. Each walker carries an elementary enthalpy during its movement. This enthalpy motion represents the thermal flux and allows to solve quantitatively the transient thermal conduction. A study demonstrates the importance of the time step chosen in the simulations. An empirical value of this parameter, based on the spatial resolution and the thermal diffusivities of the constituents, has been established to model accurately the conduction at each step of the heat transfer. Several problems related to the behavior of the walkers had to be solved to model two well-known experimental thermal characterization techniques: the hot guarded plate technique and the flash method. An imposed temperature condition is modeled by a reservoir where the number of walkers is regulated. An adiabatic wall condition imposes a specular reflection to the walkers. A stochastic transmission criterion, based on the thermal effusivities, was established to treat the behavior of a walker at voxel-voxel interface between two different constituents. Convective losses at a boundary of the numerical structure are represented by an analogous stochastic transmission criterion involving the effusivity, the convective exchange coefficient and the time step. An imposed thermal flux condition, of any temporal profile, is modeled by an injection of walkers through the boundary. The complex combination of these computing blocks allowed to model transient heat transfer within voxelised heterogeneous structures. The comparison between our results and those issued from more classical approaches allowed to validate the ability of our model to characterize the phonic thermal properties of virtual and real structures. We conclude this PhD work with preliminary activities aiming at the simulation of conduction-radiation coupling at the voxel scale of the structure: the radiative contribution is modeled by an internal power source term within the voxels
FONSECA, GABRIEL P. "Projeto e construcao de placas espalhadoras e degradadoras de energia para uso em radioterapia com feixe de eletrons para doencas de pele." reponame:Repositório Institucional do IPEN, 2010. http://repositorio.ipen.br:8080/xmlui/handle/123456789/9550.
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Dissertacao (Mestrado)
IPEN/D
Instituto de Pesquisas Energeticas e Nucleares - IPEN-CNEN/SP
Moukarzel, Camille. "Modélisation mathématique des transferts de masse et de chaleur dans des fours de verre plat." Paris, ENMP, 2003. http://www.theses.fr/2003ENMP1208.
Full textSuleiman, Ahed. "Evaluation par méthode inverse de la distribution de flux de chaleur pariétaux d'une plaque plane verticale en présence d'une perturbation radiative." Toulouse, INSA, 2002. http://www.theses.fr/2002ISAT0017.
Full textThe aim of this research is to identify, with the help of an inverse method, the value of convective heat exchanges generated by a uniformly heated vertical plane plate on which a radiative local perturbation is imposed. Experimental and numerical approaches were necessary to develop this work. The experimental system was composed of an enclosure with reduced dimensions, of the plane plate and of the radiative source of which the power was first determined by calibration. The use of the inverse method leads to the knowledge of the global flux leaving the plate and of the surface temperatures. Flux radiative calculations lead, by application of a thermal balance, to the determination of the convective heat exchanges. Finally, we can determine the values of the convective heat exchange coefficients. Two types of results are proposed. Those, corresponding to the steady state lead to the correct validation of the inverse method by comparison with a relation provided by the literature. The other ones lead in unsteady state give the evaluation of the heat exchange coefficients depending from the time. Uncertainty calculations confirm the viability of the inverse method. Finally, the main results given by this work correspond to the algorithm's robustness, which can lead to the use of the method for other applications
Josset, Damien. "Etude du couplage radar-lidar sur plates-formes spatiales et aéroportées : application à l'étude des nuages, des aérosols et de leurs interactions." Paris 6, 2009. http://www.theses.fr/2009PA066061.
Full textDemarez, Valérie. "Modélisation du transfert radiatif et télédétection hyperspectrale pour le suivi temporel de la teneur en chlorophylle d'une forêt temùpérée." Toulouse 3, 1997. http://www.theses.fr/1997TOU30284.
Full textFranceschelli, Luca. "Cooling Performance Analysis and Design of an Instrumented Radiator in a MotoGP Wind Tunnel Model." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2021.
Find full textNiezgoda, Mathieu. "Modélisation du transfert thermique au sein de matériaux poreux multiconstituants." Phd thesis, Université d'Orléans, 2012. http://tel.archives-ouvertes.fr/tel-00829217.
Full textLeray, Cedric. "Etude du comportement thermique et thermomécanique des récepteurs solaires sous haut flux radiatif." Thesis, Perpignan, 2017. http://www.theses.fr/2017PERP0003/document.
Full textFor the future, using thermodynamical solar power plant seems to be a good solution to ensure electrical production. Solar tower plants are able to produce electricity in significant amount, are environmentally friendly and economically competitive. One way to increase the yield of these plants is using high efficiency thermodynamical cycles, like combined cycle. That requires to providing a working fluid at high temperature and high pressure (10bar and 1000°C at least). This PHD thesis presents the works performed to develop and enhance a concept of modular plate solar ceramic absorber that can ensure the required air production. We chose the silicon carbide as material due to its resistance to high temperatures and oxidation problems. The drawback is ceramic modules are weak to traction stresses. The study focuses on the knowledge and the control of this phenomenon. This work combines the developments of numerical tools and experimental studies performed at Thémis power plant (Targassonne, 66, FRANCE). The numerical method permits simulations to predict the thermal behavior and the mechanical behavior of a solar module absorber. It allows the reduction of the mechanical stresses undergone by solar receiver and the prediction of its performances. This methodology was tested using experimental results
Alvarez, Nadir. "Plantes-hôtes et organisation de la diversité des insectes phytophages, des radiations évolutives aux processus populationnels : Le cas des bruches du genre Acanthoscelides Schilsky (Coleoptera : Bruchidae)." Montpellier 2, 2004. http://www.theses.fr/2004MON20127.
Full textRomero, Eric. "Modèles C. F. D. Et éléments finis pour la trempe thermique du verre plat : estimation des échanges radiatifs et convectifs, prédiction et contrôle des contraintes résiduelles." Valenciennes, 2005. http://ged.univ-valenciennes.fr/nuxeo/site/esupversions/90ecadca-bb2b-4b0c-adbf-b68adc35d34c.
Full textThe framework of the thesis is the thermal tempering of flat glass on a laboratory installation and an industrial unit with single-jet and multi-jets coolings. The first part deals with the influence of radiation in the thermal modeling for the estimation of the transient and residual stresses along the thickness. CFD 3D models are then developed to analyze the air flow and determine the convective heat transfer on the glass surface during the tempering. By coupling these with 3D finite elements models, the tempering residual stresses are computed. Photoelasticity measurements of the stresses on the surface and the thickness of the tempered glass specimens validate the numerical approach. Finally, a new ultrasonic method to control the stresses is proposed
Valdenaire, Simon. "Mise en place et utilisation des faisceaux FFF en radiothérapie : radiobiologie, caractérisation physique, contrôles qualité, modélisation et planification de traitement." Thesis, Aix-Marseille, 2017. http://www.theses.fr/2017AIXM0037/document.
Full textIn medical linear electron accelerators, photon beams profiles are homogenised using flattening filters. Technologies have evolved and the presence of this filter is no longer necessary. Flattening filter free (FFF) beams exhibit higher dose rates, heterogeneous dose profiles, modified energy spectra and lower out-of-field dose. This PhD aimed at studying the characteristics of unflattened beams, as well as their impact in clinical utilization. Several subjects were thoroughly investigated: radiobiology, dosimetry, quality controls, modelling and treatment planning. In vitro experiments ensured that the high dose-rate of FFF beams had not a radiobiological impact. A wide review of the literature was conducted to corroborate these results. In order to understand thoroughly the characteristics of FFF beams, measurements were conducted using several detectors. The effect of the spectra and dose rates of unflattened beams on dose calibration were also studied. FFF beams were modeled in two TPSs. The methods, results and model parameters have been compared between the available beam qualities as well as between both TPSs. Furthermore, the implementation of stereotactic treatments technique was the occasion to investigate small beam dosimetry. Prostate cancer cases treated with VMAT and pulmonary tumors treated with stereotactic 3D beams were also studied. The comparison of dose distributions and treatment metrics give advantage to FFF beams. Mastering physical and biological aspects of flattening filter free beams allowed the IPC to start FFF treatments. Comparative studies have since resulted in a deeper understanding on the pertinent use of these beams
Josset, Damien. "Etude du couplage radar-lidar sur plates-formes spatiales et aeroportees. Application a l'etude des nuages, des aerosols et de leurs interactions." Phd thesis, Université Pierre et Marie Curie - Paris VI, 2009. http://tel.archives-ouvertes.fr/tel-00559472.
Full textMourcin, Frédéric. "Etude de la réponse cellulaire et moléculaire des cellules souches et progéniteurs hématopoïetiques aux radiations ionisantes : implication pour la mise en place d'une thérapie cellulaire de l'aplasie médullaire radio-induite." Université Joseph Fourier (Grenoble), 2004. http://www.theses.fr/2004GRE10234.
Full textNew treatments of radio-induced bone marrow aplasia were based on the apoptosis reduction (in vivo or in vitro) of the hematopoietic stem and progenitor cells (HSPC). These approaches were founded on the heterogeneity of irradiation injury, which preserves some HSPC. The autologous cell therapy (ACT) is based on: the collect of residual HSPC and then on a phase of in vitro culture (6 to 7 days) ir the final goal to graft these expanded cells. Our work has consisted to study the fundamental mechanism of radio-induced apoptosis of HSPC before to optimise the ACT. We have used an in vitro model of irradiation of CD34+ cells come from non-human primate. Our results show a complexity of mechanisms that has been implicated in the molecular and cellular response, in case of cell cycle and apoptosis. But Caspases 1 and 6 was seen to play an important role in terms of final effectors. The cultures of irradiated cells show that 1 the negative selection of apoptotic residual HSPC before cell culture did not improve the expansion rate 2) the expansion of 4Gy irradiate CD34+ cells can only be considered with a support stromal has weil has Dexter or Mesenchymal Stem Cells 3) the sequential addition of an inhibitory of haematopoiesis (TNF-a) with a cocktail activation reduce apoptosis and increased expansion of CD34+ irradiated cells. Finally this study 1) suggest different molecular targets for new anti-apoptotic treatments and 2) show the difficulty to used the ACT in the case of an accidental irradiation