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1

Marks, Michael, Nick R. Murch, Michael A. Beckles, Anja B. Drebes, and Huw L. Beynon. "Pleuritic chest pain." Lancet 382, no. 9907 (2013): e32. http://dx.doi.org/10.1016/s0140-6736(13)62547-7.

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2

Wright, Jane, Kerstin Hogg, and Kevin Mackway-Jones. "Identifying pleuritic chest pain." Emergency Nurse 14, no. 3 (2006): 22–24. http://dx.doi.org/10.7748/en2006.06.14.3.22.c4230.

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3

Madan, V., H. L. Muston, and A. M. Marsland. "Isotretinoin-induced pleuritic chest pain." British Journal of Dermatology 156, no. 2 (2007): 385–86. http://dx.doi.org/10.1111/j.1365-2133.2006.07618.x.

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4

Greiving, Tanner, and Sumeru Mehta. "Man with Pleuritic Chest Pain." Clinical Practice and Cases in Emergency Medicine 7, no. 1 (2023): 49–50. http://dx.doi.org/10.5811/cpcem.2022.10.57915.

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Case Presentation: We describe a case of epipericardial fat necrosis. Discussion: Epipericardial fat necrosis is an inflammatory condition in which the pericardial fat pad necrotizes resulting in surrounding inflammation. This condition mimics more ominous pathology in clinical presentation and radiographic findings. Management is supportive with oral analgesics.
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5

Lee, Richard William, Luke Eliot Hodgson, Mark Basil Jackson, and Nick Adams. "Problem based review: Pleuritic Chest Pain." Acute Medicine Journal 11, no. 3 (2012): 172–82. http://dx.doi.org/10.52964/amja.0571.

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Pleuritic pain, a sharp discomfort near the chest wall exacerbated by inspiration is associated with a number of pathologies. Pulmonary embolus and infection are two common causes but diagnosis can often be challenging, both for experienced physicians and trainees. The underlying anatomy and pathophysiology of such pain and the most common aetiologies are presented. Clinical symptoms and signs that may arise alongside pleuritic pain are then discussed, followed by an introduction to the diagnostic tools such as the Wells’ score and current guidelines that can help to select the most appropriat
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6

Ozkaya, Sevket, Saliha E. Butun, Serhat Findik, Atilla Atici, and Adem Dirican. "A Very Rare Cause of Pleuritic Chest Pain: Bilateral Pleuritis as a First Sign of Familial Mediterranean Fever." Case Reports in Pulmonology 2013 (2013): 1–3. http://dx.doi.org/10.1155/2013/315751.

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The familial Mediterranean fever (FMF), also called recurrent polyserositis, is characterized by reccurrent episodes of serositis at pleura, peritoneum, and synovial membrane and fever. We present a patient with recurrent bilateral pleural effusion due to serositis attacks as a first sign of FMF. A 59-year-old Turkish man suffered from recurrent pleuritic chest pain due to pleural effusion and atelectasis. The etiology was not found, and his symptoms were spontaneously recovered during several weeks. The pleuritic chest pain was associated with abdominal pain in the last attack. The gene mutat
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7

Fazmin, Ibrahim Talal, Roy Zhang, and Claire A. Martin. "Pleuritic chest pain postcatheter ablation procedure." Heart 107, no. 19 (2021): 1543–602. http://dx.doi.org/10.1136/heartjnl-2021-319721.

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8

Gunasekaran, Kulothungan, Swetha Murthi, Narmadha Panneerselvam, Nazir Lone, and Karen McGinnis. "Rare Presentation of Pleuritic Chest Pain." Chest 148, no. 4 (2015): 623A. http://dx.doi.org/10.1378/chest.2270703.

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9

Macias, Wendy L., Christopher Kabrhel, Eric S. Nadel, and David F. M. Brown. "Pleuritic chest pain and exertional dyspnea." Journal of Emergency Medicine 29, no. 4 (2005): 467–73. http://dx.doi.org/10.1016/j.jemermed.2005.07.002.

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10

Farrell, Rory, Christopher Dare, and Katarzyna (Kasia) Hampton. "Pleuritic Chest Pain: This Can't Be Happening!" Journal of Special Operations Medicine 17, no. 4 (2017): 127. http://dx.doi.org/10.55460/izck-s7id.

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11

S Tan, Evelyn, Pierre J Willemse, and Ahmed H Abdelhafiz. "An unusual cause of ‘pleuritic’ chest pain." Acute Medicine Journal 7, no. 2 (2008): 80–82. http://dx.doi.org/10.52964/amja.0201.

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A 77 year old man presented to A&E with sudden onset left sided chest pain. This chest pain was severe enough to wake him up from sleep in the early hours of the morning. The pain was pleuritic in nature and severe enough to require administration of intravenous morphine. He had a past medical history of ischaemic heart disease (1997), pulmonary embolism (1997), and left sided pnuemothorax (1998). Drug history consisted of lansoprazole 30mg od, isosorbide mononitrate 60mg od, nicorandil 10mg bd, aspirin 75mg od, beclomethasone 100 inhaler 1 puff bd, salbutamol 100 inhaler prn and combivent
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12

Gill, S., and A. Pope. "Pleuritic chest pain: infection, infarction or musculoskeletal?" Acute Medicine Journal 1, no. 2 (2002): 64–66. http://dx.doi.org/10.52964/amja.0014.

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A 52 year old patient, originally thought to have musculoskeletal chest pain was found to have features consistent with infective pleurisy on initial blood tests and chest x-ray, with a negative d-dimer indicating a low likelihood of pulmonary embolism. Two weeks later he represented with continued symptoms and investigations revealed extensive pulmonary emboli, which were thought to have developed after his initial presentation.
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13

Spurrell, Megan, Dylan Lescure, Daniel B. Gingold, and John David Gatz. "Man With Pleuritic Chest Pain and Hemoptysis." Annals of Emergency Medicine 78, no. 2 (2021): 307–17. http://dx.doi.org/10.1016/j.annemergmed.2021.03.001.

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14

King, Lindsay Y., J. Kevin Tucker, Linda S. Lee, Bruce D. Levy, and Joseph Loscalzo. "A Complex Cause of Pleuritic Chest Pain." New England Journal of Medicine 367, no. 18 (2012): 1742–48. http://dx.doi.org/10.1056/nejmcps1208614.

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15

Hogg, K. "Accumulator BET: a traumatic pleuritic chest pain." Emergency Medicine Journal 20, no. 4 (2003): 372. http://dx.doi.org/10.1136/emj.20.4.372.

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16

Filipa, Silva, Marques Pedro, Meireles Claudia, et al. "PLEURITIC CHEST PAIN: WHAT IT MAY HIDE…" European Journal of Internal Medicine 22 (October 2011): S60. http://dx.doi.org/10.1016/s0953-6205(11)60247-1.

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17

Vaidya, Anand, Lindsay Y. King, Linda S. Lee, and J. Kevin Tucker. "A Complex Cause of Pleuritic Chest Pain." New England Journal of Medicine 367, no. 15 (2012): e21. http://dx.doi.org/10.1056/nejmimc1202552.

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18

MacGregor, J. S., A. W. Wu, and H. R. Rubin. "Pleuritic chest pain in a postpartum woman." Emergency Medicine Journal 8, no. 4 (1991): 271–73. http://dx.doi.org/10.1136/emj.8.4.271.

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19

Kumar, Pratyush, and R. S. Chahal. "Pleuritic chest pain due to migratory bullet." Current Medicine Research and Practice 6, no. 2 (2016): 101–2. http://dx.doi.org/10.1016/j.cmrp.2016.03.001.

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20

Cliff-Patel, Nikita, Baasil Syed Yusuf, Shazia Hamdani, and Veqas Ziauddin. "Familial Mediterranean fever: a differential diagnosis for the surgical abdomen." JRSM Open 13, no. 9 (2022): 205427042211234. http://dx.doi.org/10.1177/20542704221123433.

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FMF is characterised by dysregulation of the inflammatory process in the body, presenting as recurrent episodes of serositis. Patients with FMF commonly present with episodes of fever, peritonitis, synovitis, pleuritis, arthritis, and occasionally pericarditis. We present a case of a young 19-year old female, who presented to hospital four times over several months with intermittent fevers, abdominal pain and pleuritic chest pain. After being initially admitted under the surgical team, she was reviewed by the medical team who referred her for genetic testing, which subsequently confirmed the d
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21

Morgom, Marwa, Mona M. Alhaj, Sujood Musa Awadelseed, and Mohamed Taher Alasfari. "A Case of Quadruple Trouble: SLE's Multi-System Onslaught." Brazilian Journal of Case Reports 5, no. 1 (2025): bjcr33. http://dx.doi.org/10.52600/2763-583x.bjcr.2025.5.1.bjcr33.

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This case report presents a diagnostic challenge in a 27-year-old Sudanese female with no past medical history who presented to the emergency department with progressive shortness of breath and pleuritic chest pain. Investigations revealed a constellation of findings suggestive of systemic lupus erythematosus (SLE) with serositis, pleuritic chest pain, pericardial effusion, pleural effusion, and positive autoimmune markers. However, the case became further complicated by the development of acute kidney injury (AKI) and the discovery of a fixed inferior vena cava (IVC) thrombosis during her hos
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22

Samdani, Amer F., Phillip B. Storm, Eric B. Kuchner, Ira M. Garonzik, Dan Sciubba, and Benjamin Carson. "Ventriculoperitoneal Shunt Malfunction Presenting With Pleuritic Chest Pain." Pediatric Emergency Care 21, no. 4 (2005): 261–63. http://dx.doi.org/10.1097/01.pec.0000161474.42712.c9.

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23

Gopaul, Karina P., Helen M. Parry, and Damien Cullington. "Twenty-three year-old with pleuritic chest pain." Heart 105, no. 6 (2018): 464–69. http://dx.doi.org/10.1136/heartjnl-2017-312718.

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Clinical introductionA 23-year-old woman followed at another medical centre for congenital heart disease (CHD) presented to our emergency clinic with 3 weeks of bilateral pleuritic chest pain. She returned from holiday in Greece 6 weeks earlier where a tattoo and nasal piercing had been performed. There was no history of night sweats or fever.Her temperature was 37.5°C, heart rate 120 beats/min, oxygen saturations 94% on room air and blood pressure 110/74. Her chest was clear and there was systolic murmur on auscultation. The chest radiograph showed peripheral bilateral lower zone atelectasis.
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24

Zahedi, Delaram, Parisa Moori, Iqra Ashraf, and Irfan Hafeez. "Pleuritic chest pain in a young asylum seeker." Breathe 16, no. 1 (2020): 190294. http://dx.doi.org/10.1183/20734735.0294-2019.

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25

King, Paul T. "Non-pleuritic chest pain and recurrent lobar collapse." Respiratory Medicine CME 2, no. 3 (2009): 125–27. http://dx.doi.org/10.1016/j.rmedc.2008.12.007.

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26

Whiteléy, Steve. "Pulmonary embolism in outpatients with pleuritic chest pain." Annals of Emergency Medicine 17, no. 10 (1988): 1125. http://dx.doi.org/10.1016/s0196-0644(88)80466-9.

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27

Berchuck, Jacob E., and Shalini Patel. "An Often-Overlooked Etiology of Pleuritic Chest Pain." Journal of General Internal Medicine 31, no. 1 (2015): 138. http://dx.doi.org/10.1007/s11606-015-3316-4.

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28

Hull, R. D. "Pulmonary embolism in outpatients with pleuritic chest pain." Archives of Internal Medicine 148, no. 4 (1988): 838–44. http://dx.doi.org/10.1001/archinte.148.4.838.

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29

Hull, Russell D. "Pulmonary Embolism in Outpatients With Pleuritic Chest Pain." Archives of Internal Medicine 148, no. 4 (1988): 838. http://dx.doi.org/10.1001/archinte.1988.00380040078014.

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30

Sallade, T. Douglas, Chadd Kraus, and Lisa Hoffman. "Symptomatic Pericardial Cyst: An Atypical Case of Pleuritic Chest Pain." Clinical Practice and Cases in Emergency Medicine 3, no. 3 (2019): 199–201. http://dx.doi.org/10.5811/cpcem.2019.5.42601.

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Pericardial cysts were first described in 1837 as diverticula extending from the pericardium. They are rare and frequently asymptomatic. Symptomatic presentations may be similar to more common causes of chest pain or dyspnea such as acute coronary syndrome or pulmonary embolism. Emergency physicians should consider mediastinal mass, and in this case pericardial cyst, in the differential diagnosis of chest pain because of the risk for tamponade, sudden cardiac death, or other life-threatening complications. Here, we describe a novel presentation of a pericardial cyst presenting as atypical ches
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31

Lin, Frank YH, and Coleman Rotstein. "Appearances Can Be Deceiving: What Is the Diagnosis for this Community-Acquired Pneumonia?" Canadian Journal of Infectious Diseases 12, no. 1 (2001): 45–46. http://dx.doi.org/10.1155/2001/818305.

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A and asbestos exposure (in the 1970s) presented to the emergency department with a one-month history of progressive dyspnea, right-sided pleuritic chest pain, cough productive of white-coloured sputum and malaise. His health problems had commenced four months before presentation while he was vacationing at a northern Ontario resort. At that time, he had felt unwell and had developed a fever with rightsided pleuritic chest pain that radiated to his right shoulder. The diagnosis was an upper respiratory tract infection, made by the local physician; the patient was treated with a 10-day course o
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32

Wiler, Jennifer L. "Symptoms: Pleuritic Chest Pain, Dry Cough, Blood-Tinged Sputum." Emergency Medicine News 31, no. 7 (2009): 6. http://dx.doi.org/10.1097/01.eem.0000357581.86072.df.

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33

Khasawneh, Faisal A., Mansoor Mehmood, and Ruba A. Halloush. "A 19-Year-Old Woman with Pleuritic Chest Pain." Canadian Journal of Infectious Diseases and Medical Microbiology 26, no. 2 (2015): 100–102. http://dx.doi.org/10.1155/2015/652758.

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34

Cudmore, Jessica A., Wilson Lam, Iain D. C. Kirkpatrick, and Colette M. Seifer. "Pleuritic chest pain in a 58-year-old man." Heart 100, no. 16 (2014): 1271. http://dx.doi.org/10.1136/heartjnl-2014-305663.

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35

Wu, Qiong, Daniel R. Mazori, Robin Burger, Edward Heilman, and Viktoryia Kazlouskaya. "Rash Associated With Arthritis and Pleuritic Chest Pain: Answer." American Journal of Dermatopathology 42, no. 9 (2020): 710–11. http://dx.doi.org/10.1097/dad.0000000000001521.

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36

Wu, Qiong, Daniel R. Mazori, Robin Burger, Edward Heilman, and Viktoryia Kazlouskaya. "Rash Associated With Arthritis and Pleuritic Chest Pain: Challenge." American Journal of Dermatopathology 42, no. 9 (2020): e124-e125. http://dx.doi.org/10.1097/dad.0000000000001524.

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37

Lacasse, Marie-Constance, Julie Prenovault, Annick Lavoie, and Carl Chartrand-Lefebvre. "Pericardial Fat Necrosis Presenting as Acute Pleuritic Chest Pain." Journal of Emergency Medicine 44, no. 2 (2013): e269-e271. http://dx.doi.org/10.1016/j.jemermed.2012.05.032.

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38

Nayak, N., J. B. Anderson, and K. S. Channer. "Spontaneous Subcapsular Renal Haemorrhage Presenting with Pleuritic Chest Pain." Urologia Internationalis 62, no. 4 (1999): 217–19. http://dx.doi.org/10.1159/000030399.

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39

Galant-Swafford, Jessica, Matthew Light, Mark W. Onaitis, Stephen A. Rawlings, Joshua Fierer, and Judd W. Landsberg. "A 37-Year-Old Man With Pleuritic Chest Pain." Chest 156, no. 1 (2019): e15-e21. http://dx.doi.org/10.1016/j.chest.2019.02.002.

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40

Gaiba, Rahul, Edward O’Neill, and Seetha Lakshmi. "Pulmonary cryptococcosis complicating interstitial lung disease in a patient with systemic lupus erythematosus." BMJ Case Reports 12, no. 8 (2019): e229403. http://dx.doi.org/10.1136/bcr-2019-229403.

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We report a case of primary pulmonary cryptococcosis in a 59-year-old female patient with a history of systemic lupus erythematosus, interstitial lung disease and glaucoma. She presented with a cough, severe fatigue, unintentional weight loss, shortness of breath (increase in home oxygen use from baseline) and pleuritic chest pain of 2 months duration. During these 2 months, her symptoms had worsened despite multiple hospital visits, empirical antibiotics and empirical increase of her steroid dosage. Cytopathology of the bronchoalveolar lavage fluid showed yeast cells with narrow-based budding
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41

Davies, Kristen, Bradley Lonergan, Rikesh Patel, and Marwan Bukhari. "Symptomatic patients with P369S–R408Q mutations: familial Mediterranean fever or mixed auto-inflammatory syndrome?" BMJ Case Reports 12, no. 7 (2019): e228858. http://dx.doi.org/10.1136/bcr-2018-228858.

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A 51-year-old South African female of Ashkenazi Jewish descent was admitted with acute pleuritic chest pain, shortness of breath, fatigue and fever. She experienced vague abdominal and calf pains for 30 years. Her monozygotic twin was investigated independently for recurrent abdominal pain. Despite initially responding to antibiotics, treating suspected pneumonia, she developed recurrent fevers and pleuritic chest pain. After thorough investigation without significant findings, she re-attended days after discharge with similar symptoms. Familial Mediterranean fever (FMF) was suggested as she m
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42

Hashmi, Nabeel, Sourya Acharya, Shashiraj Lahoti, Saish Alegaonkar, and Samarth Shukla. "An Unusual Case of Chest Pain in a Young Adult." International Journal of Recent Surgical and Medical Sciences 03, no. 01 (2017): 056–57. http://dx.doi.org/10.5005/jp-journals-10053-0039.

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AbstractEchinococcosis is an infection caused in humans by Echinococcus granulosus which produce cystic hydatid disease. It is prevalent in most areas with livestock is raised in association with dogs. Liver is the most common site of this infection. We are presenting a case of 19-year-old adult who had chronic cough and pleuritic pain due to hydatid cyst in left lung.
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43

Sood, Nidhi, and Nikhil Sood. "A Rare Case of Vanishing Lung Syndrome." Case Reports in Pulmonology 2011 (2011): 1–2. http://dx.doi.org/10.1155/2011/957463.

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We describe here a rare case of Idiopathic Bullous Emphysema/Vanishing Lung Syndrome (VLS) in a 33-year-old male patient with a history of marijuana abuse who presents to the hospital with pleuritic chest pain thought to be due to pneumothorax based on the chest radiograph. This case emphasizes the need to obtain chest computed tomography in a relatively stable patient suspected of VLS to reduce the potential risk of overseeing a bronchopleural fistula.
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44

Fryearson, John, and Dawn Adamson. "An unusual cause of chest pain in a young woman." Obstetric Medicine 5, no. 1 (2011): 30–31. http://dx.doi.org/10.1258/om.2011.110056.

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A 25-year-old-woman presented to health-care services recurrently due to pleuritic chest pain. This increased during the first trimester of her first pregnancy. She was subsequently referred to a tertiary cardiology centre where she was seen by a cardiologist with a special interest in obstetric cardiology. After further investigations, an unusual cause of her pain was identified. Her investigations, management and her clinical course are presented here.
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45

Vamvakidou, Anastasia, Dimitris Konstantinou, Sohail Salam, and Mohsen Mahmoud. "A patient with pleuritic chest pain and abnormal blood clotting tests." Acute Medicine Journal 13, no. 4 (2014): 174–77. http://dx.doi.org/10.52964/amja.0373.

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We present the case of a 58 year old man who developed pleuritic chest while an in-patient; investigations revealed pulmonary embolism, despite a significantly raised Activated Partial Thromboplastin Time (APTT), which was subsequently attributed to Antiphospholipid syndrome (APS). The diagnosis and initial management of APS in the acute setting is discussed.
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46

Guillén, Lucía, Guillermo Telenti, Ángela Botella, and Mar Masiá. "Dyspnea and pleuritic chest pain during the COVID-19 pandemic." Enfermedades infecciosas y microbiologia clinica (English ed.) 39, no. 1 (2021): 41–42. http://dx.doi.org/10.1016/j.eimce.2020.06.007.

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47

Ceci Bonello, Rebecca, Etienne Ceci Bonello, Christian Vassallo, and Edward Giles Bellia. "Cryptogenic organising pneumonia: an unusual cause of pleuritic chest pain." BMJ Case Reports 14, no. 1 (2021): e238514. http://dx.doi.org/10.1136/bcr-2020-238514.

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A 76-year-old woman presented with a 2-hour history of pleuritic chest pain with no other associated symptoms. Blood investigations revealed raised inflammatory markers and an elevated white cell count. On chest radiograph, an airspace shadow indicative of a consolidation was prominent. This was followed by a CT scan of her thorax which showed a spiculated lesion in the right upper lobe, a lesion in the posterior segment of the left lower lobe and mildly enlarged right hilar lymph nodes. She was started on dual antibiotic therapy; however, the patient’s clinical status and inflammatory markers
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48

Louey, Stefanie, Shivanthan Shanthikumar, Moya Vandeleur, Amanda Gwee, and Phil Robinson. "Persistent pleuritic chest pain in a patient with cystic fibrosis." Breathe 18, no. 2 (2022): 220007. http://dx.doi.org/10.1183/20734735.0007-2022.

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49

Hogg, K. "Prevalence of Pulmonary Embolism in Outpatients with Pleuritic Chest Pain." Academic Emergency Medicine 12, Supplement 1 (2005): 40–41. http://dx.doi.org/10.1197/j.aem.2005.03.107.

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50

El-Kassimi, Feisal A. "Acute Pleuritic Chest Pain with Pleural Effusion and Plate Atelectasis." Chest 91, no. 2 (1987): 265–66. http://dx.doi.org/10.1378/chest.91.2.265.

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