Relevant bibliographies by topics / Podocarpic acid

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  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters

Academic literature on the topic 'Podocarpic acid'

Author: Grafiati
Published: 4 June 2021
Last updated: 26 July 2025

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Journal articles on the topic "Podocarpic acid"

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Cambie, RC, PS Rutledge, and PD Woodgate. "Transformations of Podocarpic Acid." Australian Journal of Chemistry 46, no. 10 (1993): 1447. http://dx.doi.org/10.1071/ch9931447.

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The A and C rings of the aromatic diterpenoid resin acid podocarpic acid from the heartshakes of the New Zealand conifer Dacrydium cupressinum have been modified to provide useful chiral intermediates for synthesis. The various strategies used by the Auckland group are reviewed.
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Cambie, RC, PA Craw, DK Murray, et al. "Dimers of Podocarpic Acid Derivatives." Australian Journal of Chemistry 49, no. 1 (1996): 167. http://dx.doi.org/10.1071/ch9960167.

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Treatment of methyl 12-hydroxypodocarpa-8,11,13-trien-19-oate (5) with a commercial sample of thallium(III) trifluoroacetate gave a low yield (5%) of a non-symmetric ether-linked dimer (15). Use of freshly prepared thallium(III) trifluoroacetate gave a 28% yield of the symmetrical biaryl dimer (16). The dimethyl ether (17) was prepared in low yield (10%) by treatment of methyl 12-methoxypodocarpa-8,11,13-trien-19-oate (4) with the latter reagent.
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Cambie, RC, AC Grimsdale, PS Rutledge, and PD Woodgate. "Syntheses of Confertifolin, Winterin and Isodrimenin Congeners From Podocarpic Acid." Australian Journal of Chemistry 43, no. 3 (1990): 485. http://dx.doi.org/10.1071/ch9900485.

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Podocarpic acid (11) has been converted into the congener (5) of confertifolin (4) through the o-quinone (29) formed by oxidations of the catechol monoether (15) and the 13-amine (16) with Fremy's salt. Oxidation of the methyl ether (12) afforded the p- quinone (44) which was converted into the congener (6) of winterin (7). Podocarpic acid has also been converted into the congener (8) of isodrimenin (9) through the catechol derivative (37).
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Bendall, JG, RC Cambie, AC Grimsdale, PS Rutledge, and PD Woodgate. "Synthesis of Winterin From Podocarpic Acid." Australian Journal of Chemistry 45, no. 6 (1992): 1063. http://dx.doi.org/10.1071/ch9921063.

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Ozonolysis of a hydroquinone derived from podocarpic acid (1) gave the biologically active natural product winterin (11). Treatment of the quinone (12) with ozone gave a ring-contracted spiro furanone, the mechanism of formation of which is proposed.
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Cambie, RC, PI Higgs, PS Rutledge, and PD Woodgate. "Aryne Chemistry of Podocarpic Acid Derivatives." Australian Journal of Chemistry 47, no. 8 (1994): 1483. http://dx.doi.org/10.1071/ch9941483.

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The anthranilic acid (2), a key intermediate for the generation of an aryne at C13 of podocarpic acid derivatives, was synthesized from the 14-amino compound (5) which in turn was generated regiospecifically in high yield by treatment of the 13-bromo compound (25) with sodamide in liquid ammonia. The amine was converted into the anthranilic acid by two separate routes: firstly by directed lithiation and trapping of the lithium species with a CO2 moiety, and secondly by oxidative cleavage of an isatin fused across positions 13 and 14.
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Cambie, Richard C., Perry K. Davy, Lorna H. Mitchell, Clifton E. F. Rickard, and Peter S. Rutledge. "Oxidative Decarboxylation of Podocarpic Acid Derivatives." Australian Journal of Chemistry 51, no. 8 (1998): 653. http://dx.doi.org/10.1071/c97213.

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The radical decarboxylation–sulfoxide cycloelimination of 2′-pyridylthio esters formed from a series of podocarpic acid derivatives gives Δ4(18) -alkenes in high yield. An exception is the 13-nitro acid (2) which affords a thiohydroxamic ester (28), the relative stability of which is attributed to inhibition of the radical chain reaction by the nitro group. The stereochemistry of the pyridyl sulfide (18) has been confirmed by X-ray crystallography.
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Cambie, Richard C., Michael R. Metzler, Peter S. Rutledge, and Paul D. Woodgate. "Organoiron complexes of podocarpic acid derivatives." Journal of Organometallic Chemistry 398, no. 1-2 (1990): 117–31. http://dx.doi.org/10.1016/0022-328x(90)87009-3.

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8

Cambie, Richard C., Michael R. Metzler, Clifton E. F. Rickard, Peter S. Rutledge, and Paul D. Woodgate. "Organomanganese complexes of podocarpic acid derivatives." Journal of Organometallic Chemistry 425, no. 1-2 (1992): 59–87. http://dx.doi.org/10.1016/0022-328x(92)80023-q.

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9

Cambie, RC, MR Metzler, PS Rutledge, and PD Woodgate. "Synthesis of Benzannulated Derivatives of Podocarpic Acid." Australian Journal of Chemistry 44, no. 10 (1991): 1383. http://dx.doi.org/10.1071/ch9911383.

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10

Burnell, Robert H., Michel Jean, and Sonia Marceau. "Synthesis of maytenoquinone." Canadian Journal of Chemistry 66, no. 2 (1988): 227–30. http://dx.doi.org/10.1139/v88-037.

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Dissertations / Theses on the topic "Podocarpic acid"

1

Grimsdale, Andrew Clive. "Routes to drimanes from podocarpic acid." Thesis, University of Auckland, 1989. http://hdl.handle.net/2292/2072.

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The synthesis and ozonolysis of the 6- and 7-substituted 12-hydroxypodocarpatrienes (26), (86), (90), and (98), as a possible route for the synthesis of drimanes from 12-hydroxypodocarpa-8,11,13-trien-19-oic acid (podocarpic acid) (9) has been investigated. Modification of the aromatic ring of (9) has given 11- and l4-hydroxypodocarpatrienes which were ozonised to give the congeners (31), (34), and (36) of the naturally occurring drimanes confertifolin (6), isodrimenin (7), and winterin (8). The oxidation of a 12,13-dihydroxypodocarpatriene (37) and its dimethyl ether (38) have also been inves
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2

Nguyen, Dao. "SYNTHESIS OF A NOVEL FAMILY OF AMIDE DERIVATIVES OF PODOCARPIC ACID." Master's thesis, University of Central Florida, 2004. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/2221.

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As a class, amides are of great interest in biological studies and pharmaceutical application. In this work, podocarpic acid, a natural tricyclic diterpene, derived from Podocarpus species, has been employed to form a novel family of amide derivatives which will later be studied for their potential as new drug leads. Novel amide derivatives of podocarpic acid were synthesized from podocarpic acid in three steps. The first step involved methylation with dimethylsulfate to form methyl-O-methylpodocarpate. This step was followed by iodination with iodine to give iodomethyl-O-methylpodocarpate. Fi
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3

Rhoden, Stephen. "SYNTHESIS OF NOVEL AZIRIDINE DERIVATIVES OF PODOCARPIC ACID." Master's thesis, University of Central Florida, 2007. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/3569.

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Podocarpic acid (a diterpenoid resin acid extracted from the Podocarpacea specie of plants) has shown cytotoxicity against carcinoma of the nasopharynx. Since this discovery has been made, research has been performed in order to alter the structure of the resin acid so as to increase the anticancer activity. The carboxylic acid and phenol functional groups, which are present in podocarpic acid, make it possible to synthesize new derivatives selectively at the C-15, C-13, and C-7 positions as well as by substitution of the phenol hydroxyl group. Thus numerous derivatives can be prepared, in hig
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4

Yalavarty, Manjeera. "PART I : ISOLATION OF DIPENTYL 2-(4-(PENTAN-3-YL) PHENYL) MALONATE FROM SANGUISORBA OFFICINALIS LABILL PART II: SYNTHESIS OF A NOVEL FAMILY OF ETHERS OF PODOCARPIC ACID." Master's thesis, University of Central Florida, 2005. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/4149.

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The goal of part I of this thesis was to isolate pure anti cancer compounds from the Russian plant Sanguisorba officinalis. This plant was selected for investigation because it showed 100% activity against leukemia (L1210 mouse leukemia cells) during the preliminary screening of approximately 100 Russian plant extracts. This work has resulted in the isolation of novel compound 11 using traditional chromatography techniques. Compound 11 was characterized with spectroscopic techniques such as IR, 1H NMR, 13C NMR, DEPT, DQCOSY and MS. Compound 11 was assigned the structure dipentyl 2-(4-(pentan-3
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Book chapters on the topic "Podocarpic acid"

1

Parish, Edward J., Susan Bradford, Victoria J. Geisler, et al. "Synthesis and Fungistatic Activity of Podocarpic Acid Derivatives." In ACS Symposium Series. American Chemical Society, 1987. http://dx.doi.org/10.1021/bk-1987-0325.ch009.

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