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1

Sharafutdinova, D. R., E. N. Balashova, Yu V. Kessler, et al. "Diagnostic significance of serum erythropoietin as a marker of perinatal brain damage in premature newborns with very low birth weight." Pediatric Hematology/Oncology and Immunopathology 22, no. 3 (2023): 136–45. http://dx.doi.org/10.24287/1726-1708-2023-22-3-136-145.

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The search for promising markers of brain damage in premature newborns is important for the development and optimization of individual diagnostic and therapeutic approaches to neuroprotection in neonatology. Objective: to evaluate the diagnostic significance of serum erythropoietin (sEPO) on the 1st day of life as a marker of perinatal brain damage in premature infants with very low birth weight (VLBW). The study protocol was approved by the Biomedical Research Ethics Committee (Minutes No.12 of 17 November 2016) and the Scientific Council (Minutes No.19 of 29 November 2016) of the National Me
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Alur, Pradeep, Sriharsha Talluri, Vishwarath Bollampalli, Theodore Bell, Jonathan Liss, and Prabhu Parimi. "Hypoglycemia occurs frequently in very low birth weight premature infants with cholestasis." International Journal of Contemporary Pediatrics 4, no. 5 (2017): 1572. http://dx.doi.org/10.18203/2349-3291.ijcp20173766.

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Background: The study purpose was to examine the incidence of hypoglycemia in very low birth weight (VLBW) infants with cholestasis while on complete enteral nutrition.Methods: A retrospective study of 270 VLBW (<1500 grams) infants born between 2008 and 2012 at York Hospital with cholestasis was performed. A blood glucose concentration ≤50 mg/dl was used to define hypoglycemia, and hypoglycemic events were recorded while infants were on full enteral feeds. Characteristics of infants with cholestasis were compared with those without cholestasis.Results: Cholestasis was noted in 9.6% (26/270
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3

McMurray, Jennifer. "The High-Risk Infant Is Going Home: What Now?" Neonatal Network 23, no. 1 (2004): 43–47. http://dx.doi.org/10.1891/0730-0832.23.1.43.

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EACH YEAR APPROXIMATELY 460,000 infants—nearly 12 percent of all babies born in the U.S.—are born prematurely.1 Technological advances in the medical and nursing care of premature infants over the past decade have increased survival rates among preterm newborns, especially of very low birth weight (VLBW) infants. Survival rates are as high as 49 percent for infants weighing 501–750 gm at birth, 85 percent for infants weighing 751–1,000 gm, 93 percent for infants weighing 1,001–1,250 gm, and 96 percent for infants weighing 1,251–1,500 gm.2 Although 50–60 percent of VLBW infants have normal outc
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4

Owens, Rebecca. "Intraventricular Hemorrhage in the Premature Neonate." Neonatal Network 24, no. 3 (2005): 55–71. http://dx.doi.org/10.1891/0730-0832.24.3.55.

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THE MOST COMMON VARIETY of neonatal intracranial hemorrhage is an intraventricular hemorrhage (IVH).1 Although much research has been conducted concerning the etiology and prevention of IVH in the preterm infant, the problem continues to plague very low birth weight (VLBW) infants (<1,500 grams) in particular. The risk of IVH correlates inversely with gestational age. The incidence of hemorrhage in the infant <28 weeks gestation is three times that of infants 28–31 weeks gestational age. The incidence of severe hemorrhage in infants <28 weeks gestational age is twice that of infants 2
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Hans, Deborah M., Bazak Sharon, K. Yeon Choi, Catherine M. Bendel, and Mark R. Schleiss. "Severe clinical deterioration in a preterm twin following discordant transmission of cytomegalovirus via breast milk." Journal of Neonatal-Perinatal Medicine 1, no. 3 (2008): 189–92. https://doi.org/10.3233/npm-2008-00028.

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There is clear evidence that transmission of cytomegalovirus (CMV) to infants occurs via breast milk. The precise risk for development of symptomatic CMV disease in very low birth weight (VLBW; <1500 grams at birth) premature infants following transmission from maternal breast milk is not clear, though severe disease has been described in this setting. We describe discordant transmission of CMV to VLBW twins, with severe clinical deterioration in the affected infant.
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Yoon, Young Mi, Seong Phil Bae, Yoon-Joo Kim, et al. "New modified version of the Risk Adjustment for Congenital Heart Surgery category and mortality in premature infants with critical congenital heart disease." Clinical and Experimental Pediatrics 63, no. 10 (2020): 395–401. http://dx.doi.org/10.3345/cep.2019.01522.

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Background: Despite advances in neonatal intensive care and surgical procedures, perinatal mortality rates for premature infants with congenital heart disease (CHD) remain relatively high.Purpose: We aimed to describe the outcomes of premature infants with critical CHD and identify the risk factors including the new modified version of the Risk Adjustment for Congenital Heart Surgery (M-RACHS) category associated with in-hospital mortality in a Korean tertiary center.Methods: This was a retrospective cohort study of premature infants with critical CHD admitted to the neonatal intensive care un
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7

Gülcan, Hande. "Changes in Parenteral Nutrition of Preterm Newborns." European Journal of Therapeutics 16, no. 2 (2010): 66–74. http://dx.doi.org/10.58600/eurjther.2010-16-2-1288-arch.

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The nutritional needs of premature infants are usually dependent upon parenteral nutrition (PN) during early postnatal life, especially for very low birth weight (VLBW) infants (birth weight of less than 1500 g). In these infants, full enteral feedings are generally delayed because of the severity of medical problems associated with prematurity, such as immature lung function (which often requires endotracheal intubation and mechanical ventilation), hypothermia, infections, and hypotension. In addition, early enteral feeds are also delayed because of concerns that aggressive feeding may lead t
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8

Abdullayeva, Gulban, Shayhslam Batyrhanov, Stalbek Akhunbaev, and Orozaly Uzakov. "The effects of nutritional support for premature babies with ELBW and VLBW with hypoxic damage to the central nervous system." Heart, Vessels and Transplantation 4, Issue 2 (2020): 45. http://dx.doi.org/10.24969/hvt.2020.193.

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Objective: Effect of nutritional support for preterm infants with very low (VLBW) and extremely low body (ELBW) weight with hypoxic damage of the central nervous system (CNS) of varying severity is not well elucidated. The aim of this investigation is to study clinical, laboratory, neurosonography and electroencephalography characteristics of preterm infants with VLBW and ELBW with hypoxic of CNS on complex comprehensive nutritional support, diagnostic criteria of which were infants body weight gain, increase in growth and head circumference Methods: Criteria of including into the study were V
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9

Mamun, Mohammad Abdullah Al, Md Mahbubul Hoque, MAK Azad Chowdhury, M. Monir Hossain, Mahfuza Shirin, and Lee Le Ye. "Study of Premature Infant during Early Period of Life." Northern International Medical College Journal 7, no. 1 (2015): 115–18. http://dx.doi.org/10.3329/nimcj.v7i1.25706.

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Background : There is suboptimal growth observed among the very low birth weight (VLBW) infants during postnatal period.Objectives : This study was conducted to evaluate the anthropometric parameters among preterm VLBW infants during early period of life.Methods : This was a retrospective study of preterm VLBW infants admitted to Dhaka Shishu (Children) Hospital during the period of July 2011 to June 2013. Body weight, length and occipitofrontal circumference (OFC) at birth and at 4 weeks was recorded from neonatal data base. Z-scores for each anthropometric parameter were computed using Fento
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10

Hokken-Koelega, A., and W. Cutfield. "Very low birth weight (VLBW) premature infants." Growth Hormone & IGF Research 14 (June 2004): 129. http://dx.doi.org/10.1016/j.ghir.2004.03.027.

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11

Provera, Alessandra, Erica Neri, and Francesca Agostini. "Infant-Directed Speech to Preterm Infants during the First Year Postpartum: The Influence of Preterm Birth Weight and Maternal Parenting Stress." Healthcare 12, no. 3 (2024): 401. http://dx.doi.org/10.3390/healthcare12030401.

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Premature birth can increase the level of parenting stress (PS), especially in the case of parents of high-risk infants (extremely low birth weight (ELBW) and very low birth weight (VLBW)). Though published research has explored how maternal PS influences early dyadic interactions, limited research has focused on infant-directed speech (IDS), and no studies have investigated the link between prematurity severity based on birth weight and maternal IDS. This study, involving 100 mother–infant dyads, categorized into 30 ELBW premature infants, 30 VLBW premature infants, and 40 full-term (FT) ones
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12

Chen, I.-Ling, and Hsiu-Lin Chen. "Lung Function and Relevant Clinical Factors in Very Low Birth Weight Preterm Infants with Chronic Lung Disease: An Observational Study." Canadian Respiratory Journal 2019 (August 5, 2019): 1–8. http://dx.doi.org/10.1155/2019/5824180.

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Background. Chronic lung disease (CLD), most commonly seen in premature infants who required mechanical ventilation, is associated with functional consequences on lungs and respiratory morbidity. This study aimed to evaluate the lung function of premature infants before discharge and their relevant factors related to the lung function. Methods. Very low birth weight (VLBW) preterm infants, who required respiratory support soon after birth and were admitted to a hospital in Taiwan, were enrolled. Infants with a need for supplemental oxygen or positive-pressure ventilation support at the postmen
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Isayama, Tetsuya, Fuyu Miyake, Rinawati Rohsiswatmo, et al. "Asian Neonatal Network Collaboration (AsianNeo): a study protocol for international collaborative comparisons of health services and outcomes to improve quality of care for sick newborn infants in Asia – survey, cohort and quality improvement studies." BMJ Open 14, no. 7 (2024): e082712. http://dx.doi.org/10.1136/bmjopen-2023-082712.

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IntroductionReducing neonatal deaths in premature infants in low- and middle-income countries is key to reducing global neonatal mortality. International neonatal networks, along with patient registries of premature infants, have contributed to improving the quality of neonatal care; however, the involvement of low-to-middle-income countries was limited. This project aims to form an international collaboration among neonatal networks in Asia (AsianNeo), including low-, middle- and high-income countries (or regions). Specifically, it aims to determine outcomes in sick newborn infants, especiall
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14

Vilotijevic-Dautovic, Gordana, Aleksandra Doronjski, Gordana Vijatov-Djuric, and Milena Bjelica. "Incidence of bronchopulmonary dysplasia and mortality of very low birth weight infants in Vojvodina." Srpski arhiv za celokupno lekarstvo 148, no. 1-2 (2020): 52–57. http://dx.doi.org/10.2298/sarh171227075v.

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Introduction/Objective. The incidence of bronchopulmonary dysplasia (BPD) varies depending on the prematurity rate, definition, and therapy that are applied at a certain center. The average incidence of BPD for very low birth weight infants (VLBW) in developed countries ranges 4?53%. The mortality of VLBW infants is high and represents 50% of the total neonatal and infant mortality. In recent years, the survival limits are shifted towards lower gestations. The aim of our study was to determine the incidence and severity of BPD in VLBW infants in Vojvodina and the overall mortality. Methods. Th
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Khodkevich, P. E., O. S. Fedorova, K. V. Kulikova, and I. A. Deev. "Perinatal and social predictors of early childhood health in preterm infants: multicenter cohort study results." Bulletin of Siberian Medicine 24, no. 1 (2025): 114–23. https://doi.org/10.20538/1682-0363-2025-1-114-123.

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Aim. To identify perinatal and social predictors that determine the health of premature infants in early childhood, based on their birth weight. Materials and methods. This publication is part of a cohort prospective observational study of premature infants that was initiated in Tomsk in 2014 (Deev I.A., Kulikova K.V., Kobyakova O.S. et al., 2016). The main group consisted of 226 premature infants: 78 infants with low birth weight (LBW), 76 — very low birth weight (VLBW), and 72 – extremely low birth weight (ELBW), while a control group included 76 term infants. The follow-up period was 3 year
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16

Davidson, Jennifer, Samantha Polly, Peter Hayes, Kristopher Fisher, Ajay Talati, and Tejesh Patel. "Recurrent Staphylococcal Scalded Skin Syndrome in an Extremely Low-Birth-Weight Neonate." American Journal of Perinatology Reports 07, no. 02 (2017): e134-e137. http://dx.doi.org/10.1055/s-0037-1603971.

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AbstractStaphylococcal scalded skin syndrome (SSSS) in premature infants is a rare condition. We present SSSS in an extremely low-birth-weight (ELBW) infant with recurrent and confirmed bacterial sepsis. We present it to emphasize the importance for clinicians to not only recognize the clinical manifestations of SSSS, but also the need to closely monitor infants, especially very low-birth-weight (VLBW) and ELBW infants with SSSS for recurrence and bacterial sepsis. SSSS in preterm infants is a potentially lethal condition and early recognition and appropriate supportive care could be life-savi
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17

Raschko, Paula K., Jan L. Hiller, Gerda I. Benda, Neil R. M. Buist, Kim Wilcox, and John W. Reynolds. "Nutritional Balance Studies of VLBW Infants Fed Their Mothers' Milk Fortified with a Liquid Human Milk Fortifier." Journal of Pediatric Gastroenterology and Nutrition 9, no. 2 (1989): 212–18. http://dx.doi.org/10.1002/j.1536-4801.1989.tb09858.x.

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This article reports the results of a study designed to compare human milk fortified with a liquid human milk fortifier to a preterm infant formula by analyzing the metabolic balances of certain nutrients when these milks are fed to premature infants. Ten very low birth weight (VLBW) infants were studied during 4‐day equilibration periods, then 4‐day metabolic balances of N, fat, Ca and P. while each consumed a 1:1 mixture of a pool of its own mother's milk and the liquid human milk fortifier (HM/LF). For comparison, another 10 VLBW infants were studied in similar fashion while consuming the p
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Jenkins, Randall, Katia Farnbach, and Sandra Iragorri. "Elimination of Intravenous Di-2-Ethylhexyl Phthalate Exposure Abrogates Most Neonatal Hypertension in Premature Infants with Bronchopulmonary Dysplasia." Toxics 9, no. 4 (2021): 75. http://dx.doi.org/10.3390/toxics9040075.

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(1) Background: The incidence of hypertension in very low birthweight (VLBW) infants in a single neonatal intensive care unit (NICU) dropped markedly during a 2-year period when the IV fluid (IVF) in both the antenatal unit and the NICU temporarily changed to a di-2-ethylhexyl phthalate (DEHP)-free formulation. The objective of the current report is to document this observation and demonstrate the changes in incidence of hypertension were not associated with the variation in risk factors for hypertension; (2) Methods: The charts of all VLBW infants born in a single NICU during a 7-year span we
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Acharya, N., P. Mishra, N. Shrestha, and V. Gupta. "Immediate Outcome of Vlbw And Elbw Babies in a Tertiary Care Center of Nepal." Journal of Nepalgunj Medical College 12, no. 1 (2015): 32–34. http://dx.doi.org/10.3126/jngmc.v12i1.13404.

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Background: Very Low Birth Weight (VLBW) infants weigh <1500 grams and Extremely Low Birth Weight (ELBW) infants weigh <1000 grams. They are predominantly premature but may also be associated with Intrauterine Growth Restriction (IUGR). The VLBW rate is an accurate predictor of infant mortality rate.Objective: The study was aimed to find out the hospital incidence of VLBW and ELBW babies and outcome of these babies, till they were discharged from the hospital/NICU.Methods: A descriptive study was conducted among 109 cases who weighed less than 1500 grams. The babies were evaluated for mo
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Viscardi, Rose M., Winston M. Manimtim, Chen-Chih J. Sun, Lynn Duffy, and Gail H. Cassell. "Lung Pathology in Premature Infants with Ureaplasma urealyticum Infection." Pediatric and Developmental Pathology 5, no. 2 (2002): 141–50. http://dx.doi.org/10.1007/s10024-001-0134-y.

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Respiratory tract colonization with Ureaplasma urealyticum in preterm infants has been associated with a higher incidence of pneumonia, severe respiratory failure, bronchopulmonary dysplasia (BPD), and death. In this report, we characterize the lung pathology and expression of tumor necrosis factor-α (TNF-α) associated with U. urealyticum pneumonia in very low–birth weight infants (VLBW; ≤1500 g). Lung pathology of archived autopsy specimens was retrospectively reviewed in three groups of VLBW infants: 5 gestational controls who died from nonpulmonary causes, 13 infants with pneumonia who were
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Cokro, Fonny, Lorensia Yolanda, and Shelly Caroline. "Fluconazole Effectiveness in Preventing Invasive Fungal Infection in Very Low Birth Weight Infants: Systematic Review and Meta-analysis." JURNAL ILMU KEFARMASIAN INDONESIA 20, no. 1 (2022): 14. http://dx.doi.org/10.35814/jifi.v20i1.1035.

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Fungal infections in neonates, especially in Very Low Birth Weight (VLBW) infants, are mostly caused by Candida species and may lead to morbidity and mortality. A systematic review and a meta-analysis were conducted to determine the extent to which fluconazole, an antifungal prophylactic, was effective and safe to use in VLBW or premature infants in preventing Invasive Fungal Infection (IFI), by including Randomized Controlled Trials (RCTs) carried out worldwide. The investigation started with searching process through publication databases: MEDLINE, Cochrane, ScienceDirect, and Garuda, for Ra
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Cooper, Peter A., Alan D. Rothberg, Victor A. Davies, and Andrew C. Argent. "Comparative Growth and Biochemical Response of Very Low Birthweight Infants Fed Own Mother's Milk, a Premature Infant Formula, or One of Two Standard Formulas." Journal of Pediatric Gastroenterology and Nutrition 4, no. 5 (1985): 786–94. http://dx.doi.org/10.1002/j.1536-4801.1985.tb08956.x.

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Summary:Very low birthweight (VLBW) infants weighing < 1,600 g at birth were fed their own mother's milk (OMM) or randomly assigned to receive one of three formulas: a “humanized” formula (SF), a partially modified casein‐predominant cow's milk formula (CF), or a premature formula (PF). All infants were fed at 120 kcal/kg/day where possible, PF infants had significantly greater weight increments (28.0 g/day) than those on OMM (19.4 g/day), SF (18.9 g/day), and CF (18.2 g/day). Those on PF also had greater increments of length, head circumference, and skinfold thickness than those on the oth
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Rowe, Jonelle C., Dennis E. Carey, Cynthia A. Goetz, Nancy D. Adams, and Eva Horak. "Effect of High Calcium and Phosphorus Intake on Mineral Retention in Very Low Birth Weight Infants Chronically Treated with Furosemide." Journal of Pediatric Gastroenterology and Nutrition 9, no. 2 (1989): 206–11. http://dx.doi.org/10.1002/j.1536-4801.1989.tb09857.x.

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The treatment of premature infants with the diuretic furosemide appears to be a contributory factor in the development of metabolic bone disease presumably because of furosemide‐induced hypercalciuria. In this study, we measured calcium and phosphorus balance in furosemide‐treated very low birth weight infants (VLBW) infants with bronchopulmonary dysplasia (BPD) who were fed a specialized premature formula containing increased amounts of calcium and phosphorus. Furosemide‐treated infants received 166 + 37 mg/kg/day and retained 80 + 34 mg/kg/day of calcium, and 87 + 19 mg/kg/day and retained 5
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Daily, Donna Kathryn, and Patricia Ellison. "The Premie-Neuro: A Clinical Neurologic Examination of Premature Infants." Neonatal Network 24, no. 1 (2005): 15–22. http://dx.doi.org/10.1891/0730-0832.24.1.15.

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Purpose: To develop a neurologic assessment tool, the Premie-Neuro, for very low birth weight (VLBW) infants.Instrument Development: Neurologic data were collected during the course of the NICU stay. Factor analysis was utilized to determine the strength of relationships between items and to reduce the initial number of test items.Sample: An NICU cohort of 86 preterm infants was enrolled. Mean birth weight was 1,165.8 ± 446.7 grams, and mean gestational age at birth was 28.8 ± 3.2 weeks.Method: Seventy-five neurologic and behavioral characteristics were assessed in week 1 of life and every 2 w
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Romero, Rene, and Ronald E. Kleinman. "Feeding the Very Low-Birth-Weight Infant." Pediatrics In Review 14, no. 4 (1993): 123–32. http://dx.doi.org/10.1542/pir.14.4.123.

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Unfortunately, premature birth occurs commonly in the United States. Improving the survival of very low-birth-weight (VLBW) infants depends in large part upon understanding the physiologic capabilities of their immature organ systems and providing appropriate support as they mature. Advances in the nutritional support of these infants have contributed to the better outcomes we have come to expect today, even for the smallest infants. In this review, we will discuss the limitations of gastrointestinal function and the unique nutritional requirements of very low-birth-weight infants and describe
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Karinski, Debra, Dhruv Balkundi, Lewis Rubin, and James Padbury. "The Use of Inhaled Glucocorticosteroids and Recovery from Adrenal Suppression after Systemic Steroid Use in a VLBW Premature Infant with BPD: Case Report and Literature Discussion." Neonatal Network 19, no. 8 (2000): 27–32. http://dx.doi.org/10.1891/0730-0832.19.8.27.

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Despite development of many prevention and treatment modalities for bronchopulmonary dysplasia (BPD), a form of chronic respiratory insufficiency in premature infants recovering from respiratory distress syndrome, BPD remains a treatment challenge and a significant cause of long-term morbidity. A ventilator-dependent very low birth weight infant in our newborn special care unit was receiving multiple courses of systemic dexamethasone for severe respiratory failure. The infant demonstrated adrenal suppression manifested by a baseline cortisol concentration below reported levels in infants of si
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Sukmawati, Made, I. Made Kardana, I. Wayan Dharma Artana, Putu Junara Putra, Putu Mas Vina Paramitha Cempaka, and Kartika Eda Clearesta. "Time to Achieve Full Enteral Feeding in Very Low Birth Weight Infants and Associated Factors in Neonatology Unit." Babali Nursing Research 4, no. 3 (2023): 481–91. http://dx.doi.org/10.37363/bnr.2023.43270.

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Background: Enteral intolerance in premature infants is associated with several morbidities, especially in very low birth weight (VLBW). There are only a few dietary practices to provide better outcomes in newborns with VLBW. This study aimed to assess the factors associated with the time to achieve full enteral feeding (FEF) in infants with VLBW.
 Methods: This was a retrospective study on infants with VLBW in the Neonatology Unit of Sanglah Central General Hospital, Bali from November 2020 to January 2022. The infants started trophic feeding with breastmilk and or formula milk. The age
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Neri, Erica, Alessandra Provera, and Francesca Agostini. "Paternal and Maternal Speech at 3 Months Postpartum: An Exploratory Study on the Effect of Parental Role and Birth Weight." Behavioral Sciences 14, no. 11 (2024): 1007. http://dx.doi.org/10.3390/bs14111007.

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Recent research highlights a growing interest in early interactions between fathers and their infants, acknowledging the significant influence these interactions have on developmental outcomes. However, there is a limited understanding of the specific characteristics of paternal infant-directed speech (IDS), especially in the context of premature birth. This study aimed to analyze the functional and morpho-syntactic features of paternal IDS to full-term (FT) and preterm (PT) infants at 3 months, comparing it with maternal communicative style. Additionally, the study explored the influence of t
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Anderson, Sharon. "Probiotics for Preterm Infants: A Premature or Overdue Necrotizing Enterocolitis Prevention Strategy?" Neonatal Network 34, no. 2 (2015): 83–101. http://dx.doi.org/10.1891/0730-0832.34.2.83.

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AbstractCommon among preterm, very low birth weight (VLBW) and extremely low birth weight (ELBW) infants, necrotizing enterocolitis (NEC) is a gastrointestinal, infectious disease that remains a leading cause of morbidity and mortality among this high-risk population. To combat this devastating condition, research efforts have been redirected from treatment toward prevention strategies. Although there are several proposed risk-reduction strategies, one intervention gaining support is the administration of prophylactic enteral probiotics. Regardless of growing evidentiary support and a benign s
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Gagné, David, Elmira Shajari, Marie-Pier Thibault, et al. "Proteomics Profiling of Stool Samples from Preterm Neonates with SWATH/DIA Mass Spectrometry for Predicting Necrotizing Enterocolitis." International Journal of Molecular Sciences 23, no. 19 (2022): 11601. http://dx.doi.org/10.3390/ijms231911601.

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Necrotizing enterocolitis (NEC) is a life-threatening condition for premature infants in neonatal intensive care units. Finding indicators that can predict NEC development before symptoms appear would provide more time to apply targeted interventions. In this study, stools from 132 very-low-birth-weight (VLBW) infants were collected daily in the context of a multi-center prospective study aimed at investigating the potential of fecal biomarkers for NEC prediction using proteomics technology. Eight of the VLBW infants received a stage-3 NEC diagnosis. Stools collected from the NEC infants up to
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Uberos, Jose, Sara Jimenez-Montilla, Manuel Molina-Oya, and Jose Luis García-Serrano. "Early energy restriction in premature infants and bronchopulmonary dysplasia: a cohort study." British Journal of Nutrition 123, no. 9 (2020): 1024–31. http://dx.doi.org/10.1017/s0007114520000240.

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AbstractBronchopulmonary dysplasia (BPD) is a multifactor pathology. Animal studies and cohort studies suggest that poor nutrient intake after birth increases the risk of BPD. The objective of the present study was to determine the existence of association between BPD in very low birth weight (VLBW) and energy intake during the first week of life. We recorded in a retrospective cohort study the intake of enteral and parenteral macronutrients during this period by examining the nutritional and clinical history of 450 VLBW newborns admitted to the neonatal intensive care unit. After applying the
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Collins, C., S. Drew, J. Holberton, and C. Calado. "Reference Echocardiographic Measurements in Very Low Birth Weight Preterm Infants." American Journal of Perinatology 36, no. 03 (2018): 303–10. http://dx.doi.org/10.1055/s-0038-1667070.

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Background Echocardiography is an important technique in neonatal care. The heart of a premature baby is known to be different from that of a term baby, and there is a paucity of literature regarding reference cardiac measurements for this population, especially for the very low birth weight (VLBW) infants. Objective We aimed to present reference values for echocardiography in VLBW preterm infants. Study Design This was a retrospective observational study taking place over an 11-year period. We collected data from the reports of echocardiographic examinations performed in a population of prete
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Hansen, Anne R., Margaret H. Collins, David Genest, et al. "Very Low Birthweight Infant's Placenta and Its Relation to Pregnancy and Fetal Characteristics." Pediatric and Developmental Pathology 3, no. 5 (2000): 419–30. http://dx.doi.org/10.1007/s100240010043.

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Our objective was to relate pathology of the very low birthweight (VLBW) infant's placenta to pregnancy and fetal characteristics. We correlated the pathologic features of 1146 placentas from infants with birth weights of 500–1500 g who were born between 1/1/91 and 12/ 31/93 to the number of gestations per pregnancy, initiator of preterm delivery, gestational age, birth weight Z score, and duration of rupture of membrane (ROM). Placental correlates of acute inflammation and villous edema were associated with preterm labor (PTL), pre-labor premature rupture of membranes (PROM), lower gestationa
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Rytlewski, Kacie C., Melanie Wellington, and Damian Krysan. "#45: Phenotypic heterogeneity among isolates of Candida albicans from specific anatomical niches in VLBW premature infants." Journal of the Pediatric Infectious Diseases Society 10, Supplement_2 (2021): S14. http://dx.doi.org/10.1093/jpids/piab031.031.

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Abstract Background Disseminated candidiasis is associated with high morbidity and mortality among very low birth weight (VLBW) infants. Research about C. albicans traits which lead to colonization versus invasive disease is lacking. Ability to grow in a filamentous form is a known virulence trait of C. albicans. Nevertheless, significant heterogeneity in filamentous growth in C. albicans clinical isolates has been documented (Hirakawa et. al). However, the clinical isolates investigated were obtained from varied tissue niches from hosts with differing risk factors, which could account for the
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35

Wei, Yu-Jen, Yen-Ju Chen, Yung-Chieh Lin, et al. "Respiratory Trajectory after Invasive Interventions for Patent Ductus Arteriosus of Preterm Infants." Children 8, no. 5 (2021): 398. http://dx.doi.org/10.3390/children8050398.

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Invasive interventions have been conducted in preterm infants with significant patent ductus arteriosus (PDA) when medical treatment has failed, and methods of invasive intervention have been reported. Surgical ligation via lateral thoracotomy has been a well-established procedure for decades. Recently, transcatheter occlusion has been safely and feasibly applied to the premature population. However, little research has been conducted on the benefits of transcatheter occlusion in very-low-birth-weight (VLBW) infants compared to surgical ligation. This study compared transcatheter and surgical
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36

Lin, Chung-Wei, Hsiang-Yun Ko, Chih-Chi Huang, Chiu-Yu Yeh, Yen-Chun Chiu, and Hsiu-Lin Chen. "Body Weight Gain Status during the Incubator Weaning Process in Very Low Birth Weight Premature Infants." Children 9, no. 7 (2022): 985. http://dx.doi.org/10.3390/children9070985.

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Incubator care is essential for premature infants during early hospitalization. As the infants’ conditions improve, incubator weaning becomes necessary. This retrospective study aimed to evaluate the effect of body weight gain and status of intake-calorie gain on the incubator weaning process for very low birth weight (VLBW) premature infants. The study included 127 VLBW premature neonates. We analyzed data on clinical characteristics potentially associated with the weaning period and the end-weaning body weight (EWBW), including body weight gain status, intake-calorie gain status, and disease
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37

Kim, L. V., V. A. Zhelev, G. V. Slizovsky, and E. V. Devald. "Clinical and anamnestic features of the course of necrotizing enterocolitis in premature infants." Voprosy praktičeskoj pediatrii 18, no. 4 (2023): 7–12. http://dx.doi.org/10.20953/1817-7646-2023-4-7-12.

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Objective. To study clinical, anamnestic and laboratory features and to determine risk factors for necrotizing enterocolitis (NEC) in premature infants. Patients and methods. A retrospective analysis of the medical records of 47 premature infants with very low and extremely low birth weight (VLBW/ELBW) and NEC was performed. Newborns were divided into an early-onset group (n = 22) and a lateonset group (n = 25). Groups were compared for perinatal status, clinical symptoms, laboratory findings, and clinical outcomes. As a control group, 50 children without NEC were selected. Risk factors for th
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38

Poudel, Prakash, Sunil Budhathoki, and Manoj Kumar Shrivastava. "Maternal Risk Factors and Morbidity Pattern of Very Low Birth Weight Infants: A NICU Based Study at Eastern Nepal." Journal of Nepal Paediatric Society 29, no. 2 (2009): 59–66. http://dx.doi.org/10.3126/jnps.v29i2.2040.

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Background: Preterm deliveries of babies weighing less than 1500 grams (VLBW, very low birth weight) are of major concern because of maximum perinatal morbidity and mortality found in this group. VLBW babies overload the neonatal intensive care unit (NICU) and their mortality contributes significantly to neonatal and infant mortality. Objectives: To study the common maternal risk factors associated with VLBW births. To study the morbidity and mortality patterns of VLBW babies. Methods: This was a hospital based retrospective study done in NICU of BP Koirala Institute of Health Sciences. Data w
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Lee, Eui Young, Sung Shin Kim, Ga Young Park, and Sun Hyang Lee. "Effect of red blood cell transfusion on short-term outcomes in very low birth weight infants." Clinical and Experimental Pediatrics 63, no. 2 (2020): 56–62. http://dx.doi.org/10.3345/kjp.2019.00990.

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Background: Red blood cell (RBC) transfusion improves cardiorespiratory status of preterm infants by increasing circulating hemoglobin, improving tissue oxygenation, and reducing cardiac output. However, RBC transfusion itself has also been suggested to negatively affect short-term outcomes such as intraventricular hemorrhage (IVH), bronchopulmonary dysplasia (BPD), retinopathy of prematurity (ROP), and necrotizing enterocolitis (NEC) in premature infants.Purpose: This study aimed to analyze the relationship between RBC transfusion and short-term outcomes in very low birth weight (VLBW) infant
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40

Isik, Dilek, Ahmet Bas, Zehra Arslan, Nihal Demirel, and Sezin Unal. "Inguinal Hernia Development in Very Low-Birth-Weight Infants: A Case–Control Study." European Journal of Pediatric Surgery 27, no. 04 (2016): 341–45. http://dx.doi.org/10.1055/s-0036-1593608.

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Introduction The incidence and risk factors for inguinal hernia (IH) is not a thoroughly evaluated issue of preterms. Prematurity is the single most important risk factor. There exists no study in our country which reported the incidence of IH in preterms. The purpose of this study is to investigate the incidence and time of diagnosis of IH in very low-birth-weight (VLBW) infants. Patients and Methods This retrospective case–control study was conducted in Etlik Zubeyde Hanim Women's Health Training and Research Hospital and included discharged VLBW infants with gestational age less than 32 wee
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Bhatti, Karandeep S., and Arvinder Singh. "Necrotizing enterocolitis: a case report." International Journal of Contemporary Pediatrics 7, no. 5 (2020): 1150. http://dx.doi.org/10.18203/2349-3291.ijcp20201654.

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Nectrotizing enterocilitis(NEC), a disease predominant in the premature formula fed infants, is a major cause of morbidity and mortality in NICU survivors. The symptoms may vary from apnea, fever, lethargy to abdominal distension, bloody stools, poor feeding and vomiting. The mainstay of treatment is the IV feeds, discontinuation of oral feeds, nasogastric (NG) decompression, possible breathing support and surgery. The objective of this case report is to discuss the presentation, treatment, prognosis and proposed preventative measures of NEC, which can help raise awareness and henceforth impro
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42

Frank, Lee, and Paula Christina Lecuona. "Dexamethasone and Bronchopulmonary Dysplasia." Pediatrics 98, no. 3 (1996): 514. http://dx.doi.org/10.1542/peds.98.3.514.

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With regard to the article by Jones et al entitled "Controlled Trial of Dexamethasone in Neonatal Chronic Lung Disease: A 3-Year Follow-Up" (Pediatrics. 1995;96:897-906), it is our belief that this randomized multi-center study showed no positive effect of dexamethasone (DEX) treatment in the neonates at 3 years after its use to try to reduce the incidence/severity of chronic O2-related lung disease or bronchopulmonary dysplasia (BPD).1 This summary of a large controlled trial (∼140 very low birth weight [VLBW] infants in the DEX and placebo groups) tends to support the subacute and chronic fi
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Bakhmetieva, Oksana B., Maria A. Permyakova, Sergey L. Okunev, and Maria A. Mamunts. "Prevalence of bronchopulmonary dysplasia in infants with very low body weight and extremely low body weight in Perm Krai according to the data of catamnesis department of Perinatal center." Perm Medical Journal 40, no. 3 (2023): 44–50. http://dx.doi.org/10.17816/pmj40344-50.

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Objective. To analyze the prevalence of bronchopulmonary dysplasia (BPD) in the city of Perm and Perm Krai, to state the prevalence dynamics for 3 years and BPD prevalence among infants with very low body weight (VLBW) and extremely low body weight (ELBW) from 2021 to 2021.
 Materials and methods. Examination of 271 patients aged 0 to 3 years and assessment of clinico-anamnestic, laboratory, instrumental, X-ray data according to diagnostic standards and protocols was carried out.
 Results. The number of infants diagnosed BPD in the group of preterm newborns was detected to decrease d
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44

Shi, Qinchuan, Jingjing Zhang, Chong Fan, Aixia Zhang, Zhu Zhu, and Yingying Tian. "Factors influencing hypothermia in very low/extremely low birth weight infants: a meta-analysis." PeerJ 11 (February 20, 2023): e14907. http://dx.doi.org/10.7717/peerj.14907.

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Introduction Previous studies have explored factors that influence the occurrence of hypothermia in very low/extremely low birth weight (VLBW/ELBW) infants, but the factors associated with hypothermia in VLBW or ELBW infants remain inadequately evaluated due to limited prospective data and inconsistency in study populations. Therefore, it is necessary to systematically evaluate the risk factors of hypothermia in VLBW/ELBW infants in order to provide a theoretical basis for clinical practice. Methods PubMed and other databases were used to search for case-control or cohort studies on factors in
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45

Cho, June, Xiaogang Su, and Diane Holditch-Davis. "Associations of Maternal Testosterone and Cortisol Levels With Health Outcomes of Mothers and Their Very-Low-Birthweight Infants." Biological Research For Nursing 19, no. 4 (2017): 409–18. http://dx.doi.org/10.1177/1099800417703704.

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Objective: Although the roles of testosterone and cortisol in various health problems have been extensively investigated, little is known about their associations with health outcomes in mothers and their very-low-birthweight (VLBW) infants when maternal testosterone and cortisol are examined together during the postpartum period. Method: The 101 mother–VLBW infant pairs were recruited from the neonatal intensive care unit of a tertiary medical center in the southeastern United States. Demographic information, pregnancy and labor complications of mothers, and health and growth outcomes of infa
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Chen, Wanling, Kaiping Guo, Xunbin Huang, et al. "The Association of Neonatal Gut Microbiota Community State Types with Birth Weight." Children 11, no. 7 (2024): 770. http://dx.doi.org/10.3390/children11070770.

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Background: while most gut microbiota research has focused on term infants, the health outcomes of preterm infants are equally important. Very-low-birth-weight (VLBW) or extremely-low-birth-weight (ELBW) preterm infants have a unique gut microbiota structure, and probiotics have been reported to somewhat accelerate the maturation of the gut microbiota and reduce intestinal inflammation in very-low preterm infants, thereby improving their long-term outcomes. The aim of this study was to investigate the structure of gut microbiota in ELBW neonates to facilitate the early identification of differ
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47

Wang, Xuesong, Shushu Wang, Mingwu Chen, Yong Lv, Xueyu Chen, and Chuanzhong Yang. "The value of hematocrit for predicting bronchopulmonary dysplasia in very low birth weight preterm infants." Medicine 102, no. 39 (2023): e35056. http://dx.doi.org/10.1097/md.0000000000035056.

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To determine hematocrit (HCT) and to identify independent risk factors for predicting bronchopulmonary dysplasia (BPD) in preterm infants with very low birth weight (VLBW) infants. This retrospective study included 296 premature infants with VLBW in the neonatal intensive care unit of the First Affiliated Hospital of the University of Science and Technology of China between January 2015 and December 2019. Maternal pregnant information and clinical information as well as hematological parameters of preterm babies were collected and compared. Then the maximum area under the curve of receiver ope
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48

Zlotkin, Stanley H., Deborah M. Lay, John Kjarsgaard, and Teresa Longley. "Determination of Iron Absorption Using Erythrocyte Iron Incorporation of Two Stable Isotopes of Iron (57Fe and 58Fe) in Very Low Birthweight Premature Infants." Journal of Pediatric Gastroenterology and Nutrition 21, no. 2 (1995): 190–99. http://dx.doi.org/10.1002/j.1536-4801.1995.tb11768.x.

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Summary:Due to limited erythropoiesis, iron needs for the premature infant during the first 2 months of life are low. With the potential for increased use of erythropoietin in the preterm infant, iron requirements may become markedly higher. The ability of the preterm infant to absorb iron, therefore, becomes crucial. Previous studies using single stable isotopes of iron without metabolic balances were unable to quantitatively determine iron absorption since the percentage of absorbed iron appearing in the erythrocyte could not be measured. The objective of the current study was to determine i
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Belousova, T. V., I. V. Andryushina, A. A. Novoseltseva, O. L. Bykadorova, and A. V. Lebedeva. "THE STRUCTURE OF MORBIDITY AND OUTCOMES IN NEWBORNS WITH VERY LOW AND EXTREMELY LOW BODY WEIGHT IN THE REGIONAL PERINATAL CENTER." Sibirskij medicinskij vestnik 7, no. 2 (2023): 4–11. http://dx.doi.org/10.31549/2541-8289-2023-7-2-4-11.

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Introduction. The provision of medical care to children born with very low body weight (VLBW) and extremely low body weight (ELBW) belongs to the category of tertiary level neonatal intensive care (TINC) and reflects the effectiveness of regional obstetric-gynecological, neonatology and pediatric services; and the study of the structure of morbidity and outcomes in this category of newborn babies determines methodological, organizational and medical problems of the territory. The aim of the study. To assess the structure of morbidity and outcomes in premature newborns with ELBW and VLBW at bir
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Pinaeva-Slysh, Evgeniya L., Vera A. Skvortsova, Tatyana E. Borovik, et al. "Effect of nutrition on the nutritional status in preterm infants with very low birth weight." Russian Pediatric Journal 27, no. 5 (2024): 312–21. http://dx.doi.org/10.46563/1560-9561-2024-27-5-312-321.

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Introduction. Postnatal growth retardation in premature infants with very low birth weight (VLBW) remains an unresolved problem. There are different approaches regarding the duration of use of breast milk fortifiers during breastfeeding and specialized formulas during formula feeding, as well as the timing of the appointment of complementary feeding. Objective: to evaluate the physical development and component body composition in VLBW infants, depending on nutritional support over the first year of life. Materials and methods. The study included ninety three VLBW premature infants of 2 to 11
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