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1

Lamberts, David. "Punctal Occlusion." International Ophthalmology Clinics 27, no. 1 (1987): 44–46. http://dx.doi.org/10.1097/00004397-198702710-00007.

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2

Lamberts, David W. "Punctal Occlusion." International Ophthalmology Clinics 34, no. 1 (1994): 145–50. http://dx.doi.org/10.1097/00004397-199403410-00014.

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3

Cohen, Elisabeth J. "Punctal Occlusion." Archives of Ophthalmology 117, no. 3 (1999): 389. http://dx.doi.org/10.1001/archopht.117.3.389.

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4

Im, Sung Eun, Hee Chul Lee, and Sang Soo Kim. "Tear Film and Drainage after Selective Punctal Occlusion Using Polydioxanone Plugs in Dry Eye Patients." Journal of the Korean Ophthalmological Society 64, no. 9 (2023): 759–67. http://dx.doi.org/10.3341/jkos.2023.64.9.759.

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Purpose: To assess changes in the tear film and delayed tear drainage after upper or lower, or combined upper and lower, punctal occlusion using dissolvable polydioxanone plugs in patients with dry eye.Methods: In total, 40 dry eye patients (80 eyes) were enrolled: four groups of 10 (20 eyes) with no, lower, upper, and lower and upper punctal occlusions. Dissolvable polydioxanone plugs were placed. The tear break-up time (tBUT) and the tear meniscus height (TMH) were measured, and the Schirmer I test and dye disappearance test (DDT) were performed at baseline and 2 weeks after the procedure.Re
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5

Chen, Feng, Jianhua Wang, Wei Chen, Meixiao Shen, Suzhong Xu, and Fan Lu. "Upper Punctal Occlusion versus Lower Punctal Occlusion in Dry Eye." Investigative Opthalmology & Visual Science 51, no. 11 (2010): 5571. http://dx.doi.org/10.1167/iovs.09-5097.

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6

Rashdan, Haitham, Ali Mahmoud Ismail, Mohammed Ezz-Eldawla, and Mohammed Iqbal. "Lacrimal stenting versus three-snip punctoplasty for treatment of punctal stenosis or occlusion: An open-label, randomized clinical trial." Medical Hypothesis, Discovery & Innovation in Ophthalmology 10, no. 1 (2021): 24–31. http://dx.doi.org/10.51329/mehdiophthal1418.

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Background: To compare the short-term anatomical and functional outcomes of, as well as patient satisfaction with, lacrimal stenting and three-snip punctoplasty for the treatment of punctal stenosis or occlusion.
 Methods: In this open-label, randomized clinical trial, we included 50 eyes of 30 patients diagnosed with punctal stenosis or occlusion. They were randomly allocated to two groups of 25 eyes each, using central telephone randomization. Group A underwent a lacrimal stenting procedure and was subdivided into two subgroups: Group A1 (13 eyes) received polyvinylpyrrolidone-coated pe
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7

Li, Emmy Y., Andy C. Cheng, and Hunter K. Yuen. "Non-surgical management of lacrimal canaliculitis following insertion of SmartPlug." Asian Journal of Ophthalmology 13, no. 3 (2014): 111–14. http://dx.doi.org/10.35119/asjoo.v13i3.134.

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Punctal plugs are popular device used for treatment of dry eyes. The SmartPlug, with its special thermodynamic properties, has the advantage to conform to the shape of the punctal ampulla and proximal canaliculus, and offers effective occlusion. However, SmartPlug related complications are not uncommon and surgical interventions are often required for management of persistent infection. This is a report of two middle-aged Asian women who developed chronic lacrimal canaliculitis after insertion of the SmartPlug Punctal Plug. Attempts at removing the SmartPlug failed and prolonged topical antibi
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8

Redmond, John W. "PUNCTAL OCCLUSION WITH COLLAGEN IMPLANTS." Ophthalmic Surgery, Lasers and Imaging Retina 23, no. 9 (1992): 642. http://dx.doi.org/10.3928/1542-8877-19920901-22.

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9

Groves, Stephen W., and S. Lance Forstot. "EPIPHORA AFTER PERMANENT PUNCTAL OCCLUSION." Ophthalmic Surgery, Lasers and Imaging Retina 24, no. 4 (1993): 285. http://dx.doi.org/10.3928/1542-8877-19930401-13.

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10

Yulish, Michael, and Joseph Pikkel. "Presumed Virus-Induced Punctal Occlusion." Advances in Medicine 2014 (2014): 1–4. http://dx.doi.org/10.1155/2014/809851.

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Purpose.To investigate viral infection as a cause of punctal stenosis in individuals without any ocular or systemic risk factors.Methods.The study group comprised patients with no known cause for punctal occlusion who underwent surgery at one medical center during a one-year period. Excised tissue was subjected to histological examination, PCR, and nested PCR testing for common viruses (adenovirus, influenza A and B, enterovirus, varicella-zoster, CMV, herpes simplex types 1 and 2, Epstein-Barr virus, and parainfluenza type 1).Results.All nine patients identified were female, 20–38 years of ag
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11

Benson, David R., Probadh B. Hemmady, and Robert W. Snyder. "Efficacy of Laser Punctal Occlusion." Ophthalmology 99, no. 4 (1992): 618–21. http://dx.doi.org/10.1016/s0161-6420(92)31928-1.

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12

Gjukaj, Driton, Ivanka Dacheva, and Göran Darius Hildebrand. "A Simple Step-by-Step Guide to Permanent Punctal Occlusion with the Ophthalmic Burr and Suture Technique." Klinische Monatsblätter für Augenheilkunde 240, no. 10 (2023): 1179–84. http://dx.doi.org/10.1055/a-2179-4498.

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AbstractThe medical treatment of dry eye disease usually follows a step-wise approach to achieve clinical improvement, ranging from non-surgical interventions with intensive lubrication to permanent surgical punctal occlusion. While frequent lubrication is essential, the intense regime is often too burdensome and difficult to maintain at the required frequency. Punctal plugs are an invaluable alternative approach, but also have limitations, especially in conscious children, in whom inserting and re-inserting punctum plugs in clinic can be challenging. If a patient has permanent and severe dry
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13

Kabra, Namrata Shrivallabh, Vaibhav Shivdas Patil, Akash Madhukar Bagore, and Shradha Navandar. "Preserve the reserve: The novel way." Journal of Cornea and Ocular Surface 1, no. 2 (2023): 107–12. http://dx.doi.org/10.4103/jcos.jcos_5_22.

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Abstract Aims: To assess the outcome of a novel approach for thermal punctocanalicular cautery in severe dry eye patients. Materials and Methods: After tear function tests, eligible patients with severe dry eyes recalcitrant to maximal medical therapy underwent permanent punctocanalicular occlusion by thermal punctocanalicular cauterization at a tertiary eye hospital between January 2013 and February 2018. The epithelium of the punctum, the vertical portion and the horizontal portion of the canaliculus was cauterized with long hairline tip of Ellman thermal punctal cautery. Change in Schirmer’
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14

Ervin, Ann-Margret, Andrew Law, and Andrew D. Pucker. "Punctal occlusion for dry eye syndrome: summary of a Cochrane systematic review." British Journal of Ophthalmology 103, no. 3 (2018): 301–6. http://dx.doi.org/10.1136/bjophthalmol-2018-313267.

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Dry eye disease is a disorder of the tear film associated with ocular signs and symptoms. Punctal occlusion aids the preservation of natural tears. We conducted a Cochrane systematic review to assess the effectiveness of punctal plugs for managing dry eye. Randomised and quasi-randomised trials were included. The primary outcome was symptomatic improvement (SI) at 2–12 months. Nine databases were searched with no date or language restrictions. Two authors assessed trial quality and extracted data. Summary risk ratios and mean differences were calculated. Ten trials were included. In two trials
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15

Liu, D. "Surgical punctal occlusion: a prospective study." British Journal of Ophthalmology 86, no. 9 (2002): 1031–34. http://dx.doi.org/10.1136/bjo.86.9.1031.

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16

Yazici, Bülent, Ayşe Dolar Bilge, and Faisal Naqadan. "Lacrimal Punctal Occlusion With Conjunctival Flap." Ophthalmic Plastic and Reconstructive Surgery 31, no. 4 (2015): 300–302. http://dx.doi.org/10.1097/iop.0000000000000313.

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17

Osaki, Tammy H., Ana Estela Sant’Anna, and Midori H. Osaki. "An Alternative for Permanent Punctal Occlusion." Ophthalmic Plastic and Reconstructive Surgery 33, no. 5 (2017): 395–96. http://dx.doi.org/10.1097/iop.0000000000000950.

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18

Koh, Chang Hyun, and Tae Yoon La. "Treatment of Punctal Occlusion Using Pigtail Probe." Ophthalmic Plastic and Reconstructive Surgery 29, no. 2 (2013): 139–42. http://dx.doi.org/10.1097/iop.0b013e3182805a4f.

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19

Rocha, Eduardo M., Jayter S. Paula, and Peter S. Reinach. "Punctal occlusion in Sjögren's syndrome needs clarification." Nature Reviews Rheumatology 8, no. 12 (2012): 752. http://dx.doi.org/10.1038/nrrheum.2012.53-c1.

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20

Ramos-Casals, Manuel, P. Brito-Zerón, A. Sisó-Almirall, X. Bosch, and Athanasios G. Tzioufas. "Punctal occlusion in Sjögren's syndrome needs clarification." Nature Reviews Rheumatology 8, no. 12 (2012): 752. http://dx.doi.org/10.1038/nrrheum.2012.53-c2.

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21

Miyata, Kazunori, Shinichiro Otani, Takashi Miyai, Ryohei Nejima, and Shiro Amano. "Atelocollagen Punctal Occlusion in Dry Eye Patients." Cornea 25, no. 1 (2006): 47–50. http://dx.doi.org/10.1097/01.ico.0000164783.10667.a4.

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22

Girard, Louis J., Laura Barnett, and Rosemary Rao. "A Simple, Inexpensive Technique for Punctal Occlusion." American Journal of Ophthalmology 113, no. 3 (1992): 340–41. http://dx.doi.org/10.1016/s0002-9394(14)71594-6.

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23

Pratt, David V., and James R. Patrinely. "Reversal of Iatrogenic Punctal and Canalicular Occlusion." Ophthalmology 103, no. 9 (1996): 1493–97. http://dx.doi.org/10.1016/s0161-6420(96)30478-8.

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24

Putterman, Allen M., and Michael A. Burnstine. "Reversal of Iatrogenic Punctal and Canalicular Occlusion." Ophthalmology 104, no. 6 (1997): 901. http://dx.doi.org/10.1016/s0161-6420(97)30381-9.

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25

Huang, Timothy C., and David A. Lee. "Punctal Occlusion and Topical Medications for Glaucoma." American Journal of Ophthalmology 107, no. 2 (1989): 151–55. http://dx.doi.org/10.1016/0002-9394(89)90214-6.

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26

Marx, Jeffrey L., David S. Hillman, Kevin D. Hinshaw, Jane J. Olson, Allen M. Putterman, and Sheridan Lam. "Bilateral Dacryocystitis After Punctal Occlusion With Thermal Cautery." Ophthalmic Surgery, Lasers and Imaging Retina 23, no. 8 (1992): 560–61. http://dx.doi.org/10.3928/1542-8877-19920801-14.

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27

Sakamoto, Akiko, Hiroshi Sasaki, and Kazuko Kitagawa. "Successful treatment of diabetic keratopathy with punctal occlusion." Acta Ophthalmologica Scandinavica 82, no. 1 (2004): 115–17. http://dx.doi.org/10.1111/j.1395-3907.2004.0189h.x.

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28

Wood, T. O., and R. D. Drewry. "10-0 Tarsorrhaphy/Punctal Occlusion in Corneal Transplantation." Cornea 13, no. 1 (1994): 97. http://dx.doi.org/10.1097/00003226-199401000-00039.

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29

Glatt, Herbert J. "Acute Dacryocystitis After Punctal Occlusion for Keratoconjunctivitis Sicca." American Journal of Ophthalmology 111, no. 6 (1991): 769–70. http://dx.doi.org/10.1016/s0002-9394(14)76787-x.

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30

Knapp, Mary Ellen, Bartley R. Frueh, Christine C. Nelson, and David C. Musch. "A Comparison of Two Methods of Punctal Occlusion." American Journal of Ophthalmology 108, no. 3 (1989): 315–18. http://dx.doi.org/10.1016/0002-9394(89)90123-2.

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31

Koh, Shizuka, Hitoshi Watanabe, Yuichi Hori, and Yasuo Tano. "Efficacy of Resection of Punctal Ring Combined with Thermocautery and Suturing Puncta for Permanent Occlusion." Ocular Surface 3 (January 2005): S82. http://dx.doi.org/10.1016/s1542-0124(12)70465-2.

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32

Chen, Feng, Meixiao Shen, Wei Chen, et al. "Tear Meniscus Volume in Dry Eye after Punctal Occlusion." Investigative Opthalmology & Visual Science 51, no. 4 (2010): 1965. http://dx.doi.org/10.1167/iovs.09-4349.

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33

Price, Andrew, and Bill Long. "Treatment of contact lens symptoms with punctal occlusion therapy." Contact Lens and Anterior Eye 41 (June 2018): S68. http://dx.doi.org/10.1016/j.clae.2018.03.084.

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34

Barnard, N. A. Simon. "Punctal and intracanalicular occlusion - a guide for the practitioner." Ophthalmic and Physiological Optics 16 (August 2, 2008): S15—S22. http://dx.doi.org/10.1111/j.1475-1313.1996.95001352.x.

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35

BARNARD, N. "Punctal and intracanalicular occlusion—a guide for the practitioner." Ophthalmic and Physiological Optics 16 (March 1996): S15—S22. http://dx.doi.org/10.1016/0275-5408(95)00135-2.

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36

YANG, HAO-YUNG, HIROSHI FUJISHIMA, IKUKO TODA, JUN SHIMAZAKI, and KAZUO TSUBOTA. "Lacrimal Punctal Occlusion for the Treatment of Superior Limbic Keratoconjunctivitis." American Journal of Ophthalmology 124, no. 1 (1997): 80–87. http://dx.doi.org/10.1016/s0002-9394(14)71647-2.

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37

Law, R. W. K. "Efficacy of pressure topical anaesthesia in punctal occlusion by diathermy." British Journal of Ophthalmology 89, no. 11 (2005): 1449–52. http://dx.doi.org/10.1136/bjo.2005.066969.

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38

Kaido, Minako, Eiki Goto, Murat Dogru, and Kazuo Tsubota. "Punctal occlusion in the management of chronic Stevens–Johnson syndrome." Ophthalmology 111, no. 5 (2004): 895–900. http://dx.doi.org/10.1016/j.ophtha.2003.09.034.

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39

Schroeder, Richard M., and Gregg T. Lueder. "Punctal occlusion for treatment of disabling photophobia in pediatric patients." Journal of American Association for Pediatric Ophthalmology and Strabismus 21, no. 4 (2017): e35. http://dx.doi.org/10.1016/j.jaapos.2017.07.123.

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40

Becker, B. B. "Punctal Occlusion and Blepharoplasty in Patients With Dry Eye Syndrome." Archives of Otolaryngology - Head and Neck Surgery 117, no. 7 (1991): 789–91. http://dx.doi.org/10.1001/archotol.1991.01870190101021.

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41

Garg, Aastha, Manisha Acharya, M. Vanathi, Arpan Gandhi, and Mukesh Kumar. "Acanthamoeba keratitis in a first trimester pregnancy: Challenges and management – A case report." Indian Journal of Ophthalmology - Case Reports 5, no. 2 (2025): 268–70. https://doi.org/10.4103/ijo.ijo_2170_24.

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This case report details the clinical presentation, diagnosis, and management of an eight-week pregnant 32-year-old female from urban North India with acanthamoeba keratitis (AK). The patient, a contact lens user with proper lens hygiene, presented with redness, irritation, and decreased vision in her left eye. Initial examination revealed perineural keratoneuritis and mild corneal edema. Strong clinical suspicion of AK was confirmed by corneal scraping and confocal microscopy. The patient was treated with anti-acanthamoeba drugs in consultation with her obstetrician. Due to concerns about ter
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42

Glatt, Herbert J. "Failure of Collagen Plugs to Predict Epiphora After Permanent Punctal Occlusion." Ophthalmic Surgery, Lasers and Imaging Retina 23, no. 4 (1992): 292–93. http://dx.doi.org/10.3928/1542-8877-19920401-16.

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43

Goto, Eiki, Yukiko Yagi, Minako Kaido, Yukihiro Matsumoto, Kenji Konomi, and Kazuo Tsubota. "Improved functional visual acuity after punctal occlusion in dry eye patients." American Journal of Ophthalmology 135, no. 5 (2003): 704–5. http://dx.doi.org/10.1016/s0002-9394(02)02147-5.

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44

Kojima, K. "Outcome of Punctal Plug Occlusion Therapy for Severe Dry Eye Syndrome." Japanese Journal of Ophthalmology 46, no. 6 (2002): 689–90. http://dx.doi.org/10.1016/s0021-5155(02)00592-0.

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45

Williams, D. L. "Use of punctal occlusion in the treatment of canine keratoconjunctivitis sicca." Journal of Small Animal Practice 43, no. 11 (2002): 478–81. http://dx.doi.org/10.1111/j.1748-5827.2002.tb00017.x.

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46

Nelson, Christine C., and Stephen Reed. "Argon Laser Versus Thermal Cautery for Punctal Occlusion An Animal Study." Ophthalmic Plastic & Reconstructive Surgery 7, no. 3 (1991): 173–76. http://dx.doi.org/10.1097/00002341-199109000-00004.

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47

Ohba, Emii, Murat Dogru, Eri Hosaka, et al. "Surgical Punctal Occlusion With a High Heat-Energy Releasing Cautery Device for Severe Dry Eye With Recurrent Punctal Plug Extrusion." American Journal of Ophthalmology 151, no. 3 (2011): 483–87. http://dx.doi.org/10.1016/j.ajo.2010.08.045.

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48

Aleenah Mohsin, Syeda Rabab Fatima, and Aiman Idrees. "Novel Surgical Procedure for Punctal Stenosis: Advantages of Implementation in Pakistan." Journal of the Pakistan Medical Association 73, no. 2 (2023): 463. http://dx.doi.org/10.47391/jpma.7275.

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Dear Editor, Punctal stenosis is the occlusion of the external opening of the lacrimal canaliculus. It is clinically diagnosed using fluorescein dye in addition to other methods. Over half of the population coming to ophthalmology centres for routine checkups are found to have punctal stenosis [1]. Research revealed that punctal stenosis could be caused by multiple factors such using topical anti-glaucoma medications, ectropion and chronic blepharitis. The latter, in turn, has many unknown causes, with the clinical presentation being increased lacrimation, redness and discomfort of the eyes [2
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49

Shrivastava, Saurabh, Priyanka Patkar, Reshma Ramakrishnan, and Shruti Gajera. "Punctal occlusion with Prolene suture material in the patients with dry eye." Nigerian Journal of Ophthalmology 25, no. 1 (2017): 28. http://dx.doi.org/10.4103/njo.njo_36_16.

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50

Kamoi, Mizuka, Yoko Ogawa, Murat Dogru, et al. "Spontaneous Lacrimal Punctal Occlusion Associated with Ocular Chronic Graft-versus-Host Disease." Current Eye Research 32, no. 10 (2007): 837–42. http://dx.doi.org/10.1080/02713680701586409.

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