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Journal articles on the topic 'Pyrrolo[2,3-b]pyrazine'

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Published: 24 April 2022

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1

Tesouro Vallina, Ana, and Helen Stoeckli-Evans. "Crystal structures and Hirshfeld surface analyses of two new tetrakis-substituted pyrazines and a degredation product." Acta Crystallographica Section E Crystallographic Communications 76, no. 3 (2020): 404–9. http://dx.doi.org/10.1107/s2056989020002133.

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The two new tetrakis-substituted pyrazines, 1,1′,1′′,1′′′-(pyrazine-2,3,5,6-tetrayl) tetrakis(N,N-dimethylmethanamine), C16H32N6, (I) and N,N′,N′′,N′′′-[pyrazine-2,3,5,6-tetrayltetrakis(methylene)]tetrakis(N-methylaniline), C36H40N6, (II), both crystallize with half a molecule in the asymmetric unit; the whole molecules are generated by inversion symmetry. There are weak intramolecular C—H...N hydrogen bonds present in both molecules and in (II) the pendant N-methylaniline rings are linked by a C—H...π interaction. The degredation product, N,N′-[(6-phenyl-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine-

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2

Capuano, Lilly, Birgit Dahm, Volker Port, Rudolf Schnur, and Volker Schramm. "Neue Heterocyclisierungen mit Isocyaniden 2,3-Diiminopyrrole; 4,5-Diiminoimidazole und 1H-Pyrrolo[2,3-b]pyrazine." Chemische Berichte 121, no. 2 (1988): 271–74. http://dx.doi.org/10.1002/cber.19881210211.

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3

Lassagne, Frédéric, Timothy Langlais, Elsa Caytan, et al. "From Quinoxaline, Pyrido[2,3-b]pyrazine and Pyrido[3,4-b]pyrazine to Pyrazino-Fused Carbazoles and Carbolines." Molecules 23, no. 11 (2018): 2961. http://dx.doi.org/10.3390/molecules23112961.

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2,3-Diphenylated quinoxaline, pyrido[2,3-b]pyrazine and 8-bromopyrido[3,4-b]pyrazine were halogenated in deprotometalation-trapping reactions using mixed 2,2,6,6-tetramethyl piperidino-based lithium-zinc combinations in tetrahydrofuran. The 2,3-diphenylated 5-iodo- quinoxaline, 8-iodopyrido[2,3-b]pyrazine and 8-bromo-7-iodopyrido[3,4-b]pyrazine thus obtained were subjected to palladium-catalyzed couplings with arylboronic acids or anilines, and possible subsequent cyclizations to afford the corresponding pyrazino[2,3-a]carbazole, pyrazino[2′,3′:5,6] pyrido[4,3-b]indole and pyrazino[2′,3′:4,5]p

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4

LANCELOT, JEAN-CHARLES, DANIEL LADUREE, and MAX ROBBA. "5,6-Dihydro-6-oxopyrido(2,3-e)pyrrolo (1,2-a) pyrazine and 5,6-dihydro-6-oxopyrazino(2,3-e)pyrrolo(1,2-a)pyrazine." CHEMICAL & PHARMACEUTICAL BULLETIN 33, no. 8 (1985): 3122–28. http://dx.doi.org/10.1248/cpb.33.3122.

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5

Buděšínský, Miloš, Antonín Trka, Karel Stránský, and Milan Streibl. "Heterocyclic nitrogen-containing compounds from the extract of the springtail Tetrodontophora bielanensis (WAGA)." Collection of Czechoslovak Chemical Communications 51, no. 4 (1986): 956–63. http://dx.doi.org/10.1135/cccc19860956.

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Two pyrido[2,3-b]pyrazines were isolated from the extract of the springtail Tetrodontophora bielanensis (WAGA). Their structure were determined by mass and NMR spectroscopy: 2,3-dimethoxypyrido[2,3-b]pyrazine (I) and 2-methoxy-3-isopropylpyrido[2,3-b]pyrazine (II).

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6

Volovenko, Yu M., and G. G. Dubinina. "Synthesis and Properties of 6-Amino-7-hetaryl-5-R-5H-pyrrolo[2,3-b]pyrazine-2,3-dicarbonitriles." ChemInform 34, no. 1 (2003): no. http://dx.doi.org/10.1002/chin.200301159.

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7

Sonawane, Amol D., Atsushi Shimozuma, Taro Udagawa, Masayuki Ninomiya, and Mamoru Koketsu. "Synthesis and photophysical properties of selenopheno[2,3-b]quinoxaline and selenopheno[2,3-b]pyrazine heteroacenes." Organic & Biomolecular Chemistry 18, no. 21 (2020): 4063–70. http://dx.doi.org/10.1039/d0ob00718h.

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Novel synthesis of 2-arylselenopheno[2,3-b]quinoxaline, 3-(aryl/alkylselanyl)-2-arylselenopheno[2,3-b]quinoxaline and 6-phenyl-7-(arylselanyl)selenopheno[2,3-b]pyrazine derivatives, from the corresponding 2,3-dichloroquinoxaline and 2,3-dichloropyrazine derivatives.

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8

Vadlakonda, Rajashekar, Sreenivas Enaganti, and Raghunandan Nerella. "INSILICO DISCOVERY OF HUMAN AURORA B KINASE INHIBITORS BY MOLECULAR DOCKING, PHARMACOPHORE VALIDATION AND ADMET STUDIES." Asian Journal of Pharmaceutical and Clinical Research 10, no. 2 (2017): 165. http://dx.doi.org/10.22159/ajpcr.2017.v10i2.14974.

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Objectives: To predict the anticancer potentiality of some newly designed azaindole derivatives gainst human Aurora B kinase and to identify the critical features important for their activity.Methods: Initially, the derivatives of azaindoles, (Z)-2-(oxo-1 H-pyrrolo [2,3-b] pyridine-3 (2H)-ylidene)-N-(p-substituted) hydrazine carbothioamide (scaffold A), (E)-3-((E)-substituted benzylidene hydrazono)-1H-pyrrolo[2,3-b]pyridine-2(3H)-one (scaffold B), and 1-(2-substituted acetyl)-1H- pyrrolo [2,3-b]pyridine-2,3-dione are synthesized and sketched using ACD/ChemSketch (12.0). With the 3D converted c

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9

Jiang, Alan, Qiufeng Liu, Ruifeng Wang, et al. "Structure-Based Discovery of a Series of 5H-Pyrrolo[2,3-b]pyrazine FGFR Kinase Inhibitors." Molecules 23, no. 3 (2018): 698. http://dx.doi.org/10.3390/molecules23030698.

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10

Rasmussen, Seth, Trent Anderson, Evan Culver, Furqan Almyahi, and Paul Dastoor. "Poly(2,3-dihexylthieno[3,4-b]pyrazine-alt-2,3-dihexylquinoxaline): Processible, Low-Bandgap, Ambipolar-Acceptor Frameworks via Direct Arylation Polymerization." Synlett 29, no. 19 (2018): 2542–46. http://dx.doi.org/10.1055/s-0037-1610299.

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The synthesis of a new dialkyl-functionalized quinoxaline acceptor, 5,8-dibromo-2,3-dihexylquinoxaline, is reported, along with its cross-coupling with 2,3-dihexylthieno[3,4-b]pyrazine via direct arylation polymerization. The resulting ambipolar-acceptor polymer poly(2,3-dihexylthieno[3,4-b]pyrazine-alt-2,3-dihexylquinoxaline) exhibits a low bandgap of 1.07 eV and high solubility. The results of initial organic photovoltaic devices are also reported.

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11

Berteina-Raboin, Sabine, Joana Campos, and Maria-João Queiroz. "Synthesis of New Annulated Pyrazinothienotriazolopyrimidinones and Triazolylthienopyrazines." Synthesis 50, no. 05 (2017): 1159–65. http://dx.doi.org/10.1055/s-0036-1589136.

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New pyrazino[2′,3′:4,5]thieno[2,3-e][1,2,3]triazolo[1,5-a]-pyrimidin-5(4H)-ones were synthesized in an efficient, fast, and mild one-pot procedure from methyl 7-azidothieno[2,3-b]pyrazine-6-carboxylate. From the latter, some triazolothieno[2,3-b]pyrazine-6-carboxylates were also obtained with total regioselectivity by [2+3] cycloaddition with alkynes without any metal catalyst.

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12

Jigajinni, V. B., P. N. Preston, V. K. Shah, S. W. Simpson, I. Soutar, and N. J. Stewart. "Structure-property relationships in PMR-15-type polyimide resins: IIH. New polyimides incorporating triazoles, quinoxalines, pyridopyrazines and pyrazinopyridazines." High Performance Polymers 5, no. 3 (1993): 239–57. http://dx.doi.org/10.1088/0954-0083/5/3/008.

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Polyimide oligomers (prepolymers) and resins of the PMR-15 type have been prepared from 5-norbomene-2,3-dicarboxylic half acid ester (NE), 3,3',4,4'-benzophenone tetracarboxylic diester (BTDE) and a series of diamines incorporating 1,2,3-triazole, quinoxaline, pyrido[2,3-b]pyrazine, pyrido[3,4-b]pyrazine, benzo[g]quinoxaline, pyrazino-[2,3]-d]pyridazine and bis(pyrido[3,4-b]pyrazino)benzene ring systems. Two tetraamines in the bis(pyrazino[2,3-d]pyridazino)benzene ring system were also employed. Selected diamine monomers from the above ring systems provde PMR-15-analogue resins of higher therm

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13

Dannhoffer, L., P. Melin, C. Faveau, et al. "Activation of chloride secretion in human airway epithelial cells by a new pyrrolo[2,3-b]pyrazine." Journal of Cystic Fibrosis 7 (June 2008): S18. http://dx.doi.org/10.1016/s1569-1993(08)60067-3.

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14

Gala, Elena, Marta Cordoba, M. Luisa Izquierdo, and Julio Alvarez-Builla. "Gold catalysis in the synthesis of azaindoles: pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrazines." Arkivoc 2014, no. 5 (2014): 319–40. http://dx.doi.org/10.3998/ark.5550190.p008.720.

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15

Iaroshenko, Viktor, Yan Wang, Dmitri Sevenard, and Dmitriy Volochnyuk. "Synthesis of Fluorinated Pyrrolo[2,3-b]pyridine and Pyrrolo[2,3-d]pyrimidine Nucleosides." Synthesis 2009, no. 11 (2009): 1851–57. http://dx.doi.org/10.1055/s-0029-1216640.

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16

Deeb, Ali, Besher Bayoumy, Fathy Yasine, and Rida Fikry. "Pyridazine Derivatives and Related Compounds, Part 4. Pyrrolo[2,3-c]pyridazines and Furo[2,3-c]pyndazines, Synthesis and Some Reactions." Zeitschrift für Naturforschung B 47, no. 3 (1992): 418–23. http://dx.doi.org/10.1515/znb-1992-0320.

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Ethyl 5-amino-3,4-diphenyl-7H-pyrrolo[2,3-c]pyridazine-6-carboxylate (1), ethyl 5-aminofuro[ 2,3-c]pyridazine-6-carboxylate (2) and 5-aminofuro[2,3-c]pyridazine-6-carboxamide (3), are obtained from 4-cyano-5,6-diphenyl-3(2H)-pyridazinone. 5-Acetamido and 5-chloroacetamido derivatives prepared from 1, undergo cyclization on heating to form 2-substituted pyridazino[4',3':4,5]pyrrolo[3,2-d]oxazin-4(5H)-one (5a, b). The reaction of 1 and 2 with hydrazine gave 6-carbohydrazide derivatives (7 a, b). Compound 3 undergoes condensation with acetyl chloride, chloroacetyl chloride, benzoyl chloride, form

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17

Loloiu, G., T. Loloiu, and O. Maior. "Synthesis of 1H-pyrrolo[2,3-b]phenoxathiin-2,3-dione." Chemistry of Heterocyclic Compounds 34, no. 3 (1998): 363–66. http://dx.doi.org/10.1007/bf02290733.

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18

Hordiyenko, Olga, Angelina Biitseva, Igor Rudenko, Iryna Omelchenko, and Axelle Arrault. "Synthesis of 5H-Pyrrolo[3,4-b]pyrazine-Based Peptidomimetics." Synthesis 47, no. 23 (2015): 3733–40. http://dx.doi.org/10.1055/s-0035-1560184.

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19

Fun, Hoong-Kun, Madhukar Hemamalini, Anita Hazra, and Shyamaprosad Goswami. "Methyl pyrido[2,3-b]pyrazine-3-carboxylate." Acta Crystallographica Section E Structure Reports Online 67, no. 11 (2011): o3120. http://dx.doi.org/10.1107/s1600536811044412.

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20

Wang, Cui-ping, Jing-bo Yan, Hai-Jun Chi, Yan Dong, and Zhi-qiang Zhang. "3-(4-Methoxyphenyl)pyrido[2,3-b]pyrazine." Acta Crystallographica Section E Structure Reports Online 66, no. 10 (2010): o2650. http://dx.doi.org/10.1107/s1600536810037943.

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21

Okamoto, Yoshinari, Yumiko Kaneda, Tetsuo Yamasaki, Tadashi Okawara, and Mitsuru Furukawa. "Simple preparation of fused pyrrolo[2,3-b]pyrrolidinones and pyrrolo[2,3-c]pyridazinones 1." Journal of the Chemical Society, Perkin Transactions 1, no. 9 (1997): 1323–28. http://dx.doi.org/10.1039/a607816h.

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22

Popek, Rafal, and Guy Crundwell. "Crystal structures of 2,3-bis(thiophen-2-yl)pyrido[2,3-b]pyrazine and 7-bromo-2,3-bis(thiophen-2-yl)pyrido[2,3-b]pyrazine." Acta Crystallographica Section E Crystallographic Communications 75, no. 1 (2019): 89–93. http://dx.doi.org/10.1107/s2056989018016882.

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The crystal structures of 2,3-bis(thiophen-2-yl)pyrido[2,3-b]pyrazine, C15H9N3S2 (1), and 7-bromo-2,3-bis(thiophen-2-yl)pyrido[2,3-b]pyrazine, C15H8BrN3S2 (2), are discussed. Both molecules crystallize in space group P21/c. In 1, the thienyl rings are inclined to the mean plane of the pyridopyrazine moiety by 6.16 (7) and 86.66 (8)°, where as in 2 the corresponding dihedral angles are 33.29 (11) and 19.84 (9)°. The pyridopyrazine moiety is relatively planar in 1 with the two rings being inclined to each other by 1.33 (7)°. In 2, however, the pyridopyrazine moiety is buckled with the correspond

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23

Evers, David L., Julie M. Breitenbach, Katherine Z. Borysko, Leroy B. Townsend, and John C. Drach. "Inhibition of Cyclin-Dependent Kinase 1 by Purines and Pyrrolo[2,3-d]Pyrimidines Does Not Correlate with Antiviral Activity." Antimicrobial Agents and Chemotherapy 46, no. 8 (2002): 2470–76. http://dx.doi.org/10.1128/aac.46.8.2470-2476.2002.

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ABSTRACT We have previously shown that a series of nonnucleoside pyrrolo[2,3-d]pyrimidines selectively inhibit the replication of herpes simplex virus type 1 (HSV-1) and human cytomegalovirus (HCMV). These compounds act at the immediate-early or early stage of HCMV replication and have antiviral properties somewhat similar to those of roscovitine and olomoucine, specific inhibitors of cyclin-dependent kinases (cdks). In the present study we examine the hypothesis that pyrrolo[2,3-d]pyrimidines exert their antiviral effects by inhibition of cellular cdks. Much higher concentrations of a panel o

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24

Effi, Yamien, Jean-Charles Lancelot, Sylvain Rault, and Max Robba. "Pyrrolothiénopyrazines: Etude chimique de la pyrrolo[1,2-a]thiéno[2,3-e]pyrazine." Journal of Heterocyclic Chemistry 23, no. 1 (1986): 17–23. http://dx.doi.org/10.1002/jhet.5570230105.

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25

Wang, Yanling, Qiang Peng, Ping He, Zaifang Li, Ying Liang, and Benlin Li. "Theoretical Design Study on Photophysical Properties of Light-emitting Pyrido[3,4-b]pyrazine-based Oligomers." Australian Journal of Chemistry 65, no. 2 (2012): 169. http://dx.doi.org/10.1071/ch11427.

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The electronic structures, charge injection and transport, and absorption and emission properties of four series of dimethylpyrido[3,4-b]pyrazine-based oligomers (5-(5,5-dimethyl-5H-dibenzo[b,d]silol-3-yl)-2,3-dimethylpyrido[3,4-b]pyrazine)n (SPP)n, (5-(dibenzo[b,d]thiophen-3-yl)-2,3-dimethylpyrido[3,4-b]pyrazine)n (TPP)n, (5-(9,9-dimethyl-9H-fluoren-2-yl)-2,3-dimethylpyrido[3,4-b]pyrazine)n (FPP)n, (2-(2,3-dimethylpyrido[3,4-b]pyrazin-5-yl)-9-methyl-9H-carbazole)n (PPC)n were investigated by the density functional theory approach. The ground-state geometries of (SPP)n, (TPP)n, (FPP)n and (PPC

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26

Ghotekar, Bhausaheb K., Muddassar A. Kazi, Madhukar N. Jachak, and Raghunath B. Toche. "Effect of substituents on absorption and fluorescence properties of pyrazolo[3,4-b]pyrrolo[2,3-d]pyridines." Canadian Journal of Chemistry 86, no. 11 (2008): 1070–76. http://dx.doi.org/10.1139/v08-155.

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A convenient route was successfully developed for the synthesis of novel heterocycles such as pyrazolo[3,4-b]pyrrolo[2,3-d]pyridines (PPP) from pyrazolo[3,4-b]pyridines in good yield. The PPP derivatives synthesized were further studied for their photophysical properties, and it was observed that absorption and emission λmax changed, owing to the substituent effect at 4 positions. These compounds were obtained from highly reactive starting materials, 5-aminopyrazoles and α-acetyl γ-butyrolactone.Key words: α-acetyl γ-butyrolactone, pyrazolo[3,4-b]pyrrolo[2,3-d] pyridine, absorption, emission,

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27

Štarha, Pavel, and Zdeněk Trávníček. "5-Bromo-1H-pyrrolo[2,3-b]pyridine." Acta Crystallographica Section E Structure Reports Online 69, no. 3 (2013): o381. http://dx.doi.org/10.1107/s1600536813004157.

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28

Minakata, Satoshi, Shinobu Itoh, Mitsuo Komatsu, and Yoshiki Ohshiro. "Functionalization of 1H-Pyrrolo[2,3-b]pyridine." Bulletin of the Chemical Society of Japan 65, no. 11 (1992): 2992–97. http://dx.doi.org/10.1246/bcsj.65.2992.

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29

Karpov, Sergey, Arthur Grigor’ev, Yakov Kayukov, Iuliia Gracheva, and Victor Tafeenko. "Cascade Regioselective Heterocyclization of 2-Acyl-1,1,3,3-tetracyanopropenides: Synthesis of Pyrrolo[3,4-c]pyridine and Pyrrolo[3,4-d]thieno[2,3-b]pyridine Derivatives." Synlett 28, no. 13 (2017): 1592–95. http://dx.doi.org/10.1055/s-0036-1588823.

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2-Acyl-1,1,3,3-tetracyanopropenides (ATCN) undergo cascade heterocyclization under the action of aliphatic thiols, resulting in the formation of 6-(alkylthio)-4-amino-1-aryl(alkyl)-1-hydroxy-3-oxo-2,3-dihydro-1H-pyrrolo[3,4-c]pyridine-7-carbonitriles. The involvement of methyl mercaptoacetate to this reaction leads to the formation of the methyl 4,8-diamino-1-aryl-1-hydroxy-3-oxo-2,3-dihydro-1H-pyrrolo[3,4-d]thieno[2,3-b]pyridine-7-carboxylates, containing a new fused heterocyclic scaffold.

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30

Han, Jianxin, Sheng-Tong Niu, Yushuang Liu, et al. "Robustanoids A and B, two novel pyrrolo[2,3-b]indole alkaloids from Coffea canephora: isolation and total synthesis." Organic Chemistry Frontiers 5, no. 4 (2018): 586–89. http://dx.doi.org/10.1039/c7qo00931c.

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31

Arcadi, Antonio, Sandro Cacchi, Giancarlo Fabrizi, and Luca M. Parisi. "2,3-Disubstituted pyrrolo[2,3-b]quinoxalines via aminopalladation–reductive elimination." Tetrahedron Letters 45, no. 11 (2004): 2431–34. http://dx.doi.org/10.1016/j.tetlet.2004.01.058.

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32

Hordiyenko, Olga, Igor Rudenko, Irina Zamkova, et al. "Facile Synthesis of Hydrazine Derivatives of 5H-Pyrrolo[3,4-b]pyrazine and 1H-Pyrrolo[3,4-b]quinoxaline." Synthesis 45, no. 24 (2013): 3375–82. http://dx.doi.org/10.1055/s-0033-1340042.

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33

Blache, Y., A. Gueiffier, O. Chavignon, et al. "Heterocyclizations in the pyrido[2,3-b]pyrazine series." Journal of Heterocyclic Chemistry 31, no. 1 (1994): 161–66. http://dx.doi.org/10.1002/jhet.5570310127.

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34

Cugola, Alfredo, Daniele Donati, M. Guarneri, et al. "Synthesis and biological evaluation of pyrido[2,3-b]pyrazine and pyrido[2,3-b]pyrazine-n-oxide as selective glycine antagonists." Bioorganic & Medicinal Chemistry Letters 6, no. 22 (1996): 2749–54. http://dx.doi.org/10.1016/s0960-894x(96)00492-1.

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35

Bathula, Chandramohan, Catarina Roma-Rodrigues, Jyoti Chauhan, Alexandra R. Fernandes та Subhabrata Sen. "Synthesis of tetrahydro-1H-indolo[2,3-b]pyrrolo[3,2-c]quinolones via intramolecular oxidative ring rearrangement of tetrahydro-β-carbolines and their biological evaluation". New Journal of Chemistry 42, № 8 (2018): 6538–47. http://dx.doi.org/10.1039/c7nj04616b.

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36

Savelli, Francesco, Alessandro Boido, and Gianluca Damonte. "Synthesis of 1H-pyrazino[1,2-a]pyrido[2,3-e]pyrazine and 2H-Pyrano[2,3-b]pyrido[2,3-e]pyrazine Derivatives." Journal of Heterocyclic Chemistry 33, no. 6 (1996): 1737–42. http://dx.doi.org/10.1002/jhet.5570330632.

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37

Li, Peng-Hui, Ping Zeng, Shuo-Bin Chen, et al. "Synthesis and Mechanism Studies of 1,3-Benzoazolyl Substituted Pyrrolo[2,3-b]pyrazine Derivatives as Nonintercalative Topoisomerase II Catalytic Inhibitors." Journal of Medicinal Chemistry 59, no. 1 (2015): 238–52. http://dx.doi.org/10.1021/acs.jmedchem.5b01284.

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38

Jaime-Figueroa, Saul, Javier De Vicente, Johannes Hermann, et al. "Discovery of a series of novel 5H-pyrrolo[2,3-b]pyrazine-2-phenyl ethers, as potent JAK3 kinase inhibitors." Bioorganic & Medicinal Chemistry Letters 23, no. 9 (2013): 2522–26. http://dx.doi.org/10.1016/j.bmcl.2013.03.015.

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39

Yang, Zhao-Ying, Tian Tian, Ya-Fei Du, et al. "Direct intramolecular amination of tryptophan esters to prepare pyrrolo[2,3-b]indoles." Chemical Communications 53, no. 57 (2017): 8050–53. http://dx.doi.org/10.1039/c7cc03983b.

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40

LOLOIU, G., T. LOLOIU, and O. MAIOR. "ChemInform Abstract: Synthesis of 1H-Pyrrolo[2,3-b]phenoxathiin-2,3-dione." ChemInform 29, no. 38 (2010): no. http://dx.doi.org/10.1002/chin.199838169.

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41

Groth, Ulrich, Viktor Iaroshenko, Yan Wang, and Thomas Wesch. "Facile Synthesis of Fluorinated Pyrrolo[2,3-b]pyridines." Synlett 2009, no. 03 (2009): 456–60. http://dx.doi.org/10.1055/s-0028-1087530.

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42

Selig, Roland, Dieter Schollmeyer, Wolfgang Albrecht, and Stefan Laufer. "2-(3,4,5-Trimethoxyphenyl)-1H-pyrrolo[2,3-b]pyridine." Acta Crystallographica Section E Structure Reports Online 65, no. 12 (2009): o3097. http://dx.doi.org/10.1107/s1600536809047540.

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Shirai, Kazuko, Koushi Fukunishi, Dongfeng Hou, and Masaru Matsuoka. "Syntheses of 2,3-dicyano-5a,8a-dihydro-5a-hydroxycyclopentano[1′,2′:4,5]pyrrolo[2,3-b]pyrazines and 2,3-dicyanocyclohexano[1′,2′:4,5]pyrrolo-[2,3-b]pyrazines." Journal of Heterocyclic Chemistry 37, no. 5 (2000): 1299–304. http://dx.doi.org/10.1002/jhet.5570370546.

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Kapse, Deepak M., Pooja S. Singh, Mohammed Ghadiyali, Sajeev Chacko, and Rajesh M. Kamble. "Blue-red emitting materials based on a pyrido[2,3-b]pyrazine backbone: design and tuning of the photophysical, aggregation-induced emission, electrochemical and theoretical properties." RSC Advances 12, no. 11 (2022): 6888–905. http://dx.doi.org/10.1039/d2ra00128d.

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Prakash, K. S., and Rajagopal Nagarajan. "Copper-catalyzed heteroannulation: a simple route to the synthesis of pyrrolo[2,3-b]carbazole and pyrrolo[2,3-b]quinoline derivatives." Tetrahedron Letters 56, no. 1 (2015): 69–72. http://dx.doi.org/10.1016/j.tetlet.2014.10.070.

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Keivanloo, Ali, Mohammad Bakherad, Hossein Nasr-Isfahani, and Somayeh Esmaily. "Highly efficient synthesis of 5,6-disubstituted-5H-pyrrolo[2,3-b]pyrazine-2,3-dicarbonitriles through a one-pot palladium-catalyzed coupling reaction/cyclization in water." Tetrahedron Letters 53, no. 25 (2012): 3126–30. http://dx.doi.org/10.1016/j.tetlet.2012.04.016.

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Volovenko, Yu M., and G. G. Dubinina. "ChemInform Abstract: Synthesis of 6-Amino-5-R2-7- (6-R1-4-oxo-3,4-dihydro-2-quinazolyl)-5H-pyrrolo [2,3-b]pyrazine-2,3-dicarbonitriles." ChemInform 33, no. 43 (2010): no. http://dx.doi.org/10.1002/chin.200243192.

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Hordiyenko, Olga V., Igor V. Rudenko, Irina A. Zamkova, et al. "ChemInform Abstract: Facile Synthesis of Hydrazine Derivatives of 5H-Pyrrolo[3,4-b]pyrazine and 1H-Pyrrolo[3,4-b]quinoxaline." ChemInform 45, no. 23 (2014): no. http://dx.doi.org/10.1002/chin.201423139.

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O. Abdelhamid, Abdou, Fathy M. Abdel-Galil, and Sohair S. Saleh. "Reactions with Heterocyclic Enaminonitriles: Synthesis of Pyrrolo[2,3-b]pyridine, Pyrrolo[2,3-d]pyrimidine and Pyrrole Derivatives." HETEROCYCLES 27, no. 8 (1988): 1861. http://dx.doi.org/10.3987/com-87-4432.

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Abdel-Mohsen, Shawkat A., and Ahmed A. Geies. "A convenient synthesis of pyrrolo[2,3-b]pyridines and pyrido[2′,3′:5,4]pyrrolo[2,3-d]pyrimidines." Monatshefte für Chemie - Chemical Monthly 139, no. 10 (2008): 1233–40. http://dx.doi.org/10.1007/s00706-007-0839-3.

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