Log in

Relevant bibliographies by topics / Quinazolin-4(3H)-one; antibacterial activity; Nucleophile

Contents

Journal articles

Academic literature on the topic 'Quinazolin-4(3H)-one; antibacterial activity; Nucleophile'

Author: Grafiati

Published: 4 June 2025

Last updated: 1 August 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Quinazolin-4(3H)-one; antibacterial activity; Nucleophile.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "Quinazolin-4(3H)-one; antibacterial activity; Nucleophile"

1

Osarumwense, Osarodion Peter. "Synthesis and antibacterial activity of 3-amino-6-iodo-2-methyl quinazolin 4-(3H)-one and 6-iodo-2-methyl-4H-benzo [D] [1, 3] oxazin-4-one." World Journal of Advanced Research and Reviews 2, no. 3 (2019): 014–20. https://doi.org/10.5281/zenodo.4309464.

Full text

Abstract:

Quinazolines and its derivatives represent one of the most active classes of compounds, which possess wide range of biological activities like anti-bacterial, analgesic, anti-microbial, anti-inflammatory, anticancer, and anti-hypertensive ,antifungal, anti-HIV, antioxidant, analgesic, anticonvulsant, antimalarial, antitumor, anti-tubercular activities. The objective of the present study was to synthesize these quinazolinone derivatives 6-iodo-2-methyl-4H-benzo[d]-[1,3]-oxazin-4-one and 3-amino-6-iodo-2—methyl-3H-quinazolin-4-one and evaluate them for their antibacterial activity. 6-lodo-

APA, Harvard, Vancouver, ISO, and other styles

2

Osarumwense, Peter Osarodion. "Synthesis and antibacterial activity of newly synthesized 7-chloro–2–methyl-4h–benzo[d] [1, 3]–oxazin–4–one and 3–amino-7-chloro-2–methyl-quinazolin-4(3h)–one." GSC Biological and Pharmaceutical Sciences 11, no. 1 (2020): 212–20. https://doi.org/10.5281/zenodo.4277223.

Full text

Abstract:

The current study is aimed at the synthesis of these quinazolinone derivatives 7-Chloro-2-Methyl-4H-benzo[d]-[1,3]-Oxazin-4-one and 3-Amino-7-Chloro-2—Methyl-3H-Quinazolin-4-One and evaluate them for their antibacterial activity.The condensation of 2-amino-methyl-4-methoxybenzoate with acetic anhydride yielded the cyclic compound 2-methyl-4, 5-disubstituted-1, 3-benzo-oxazine-4-one which further produce a novel 2,3-disubstituted quinazolin-4 ones via the reaction with hydrazine hydrate The quinazolinone derivatives 7-chloro-2-methyl-4H-benzo[d][1,3]-oxazin-4-one and 3-amino-7-chloro-2-me

APA, Harvard, Vancouver, ISO, and other styles

3

Peter Osarodion Osarumwense, Mary Olire Edema, and Cyril Odianosen Usifoh. "Synthesis and antibacterial activities of quinazolin-4(3h)-one, 2-methyl-4(3h)-quinazolinone and 2–phenyl-4(3h)-quinazolinone." International Journal of Biological and Pharmaceutical Sciences Archive 1, no. 2 (2021): 077–84. http://dx.doi.org/10.30574/ijbpsa.2021.1.2.0027.

Full text

Abstract:

Background: Quinazoline and quinazolinone scaffolds represent an important class of biologically active nitrogen heterocyclic compounds. Many marketed drugs are based on these moieties. A diverse range of molecules with quinazoline/quinazolinone moieties have been reported to exhibit broad spectrum of biological activities Objective: This study is aimed at the synthesis of these quinazolinone derivatives, quinazolin-4(3H)-One, 2-Methyl-4(3H)-quinazolinone and 2–Phenyl-4(3H)-quinazolin-4(3H)–one and evaluate them for their antibacterial activities. Method: The consolidation of 2-amino-methyl-4-

APA, Harvard, Vancouver, ISO, and other styles

4

Appani, Ramgopal, Baburao Bhukya, and Kiran Gangarapu. "Synthesis and Antibacterial Activity of 3-(Substituted)-2-(4-oxo-2-phenylquinazolin-3(4H)-ylamino)quinazolin-4(3H)-one." Scientifica 2016 (2016): 1–5. http://dx.doi.org/10.1155/2016/1249201.

Full text

Abstract:

A series of novel 3-(substituted)-2-(substituted quinazolinylamino)quinazolin-4(3H)-ones were synthesized by the reaction of 3-(substituted)-2-hydrazino-quinazoline-4(3H)-ones with 2-phenyl-3,1-benzoxazin-4-one. The starting materials 3-(substituted)-2-hydrazino-quinazolin-4(3H)-ones were synthesized from various primary amines by a multistep synthesis. All the title compounds were tested for their antibacterial activity using ciprofloxacin as reference standard. Compounds 3-(4-fluorophenyl)-2-(4-oxo-2-phenylquinazolin-3(4H)-ylamino)quinazolin-4(3H)-one (9a) and 3-(4-chlorophenyl)-2-(4-oxo-2-p

APA, Harvard, Vancouver, ISO, and other styles

5

Sulthana, M. T., K. Chitra, and V. Alagarsamy. "Anti-HIV, Antitubercular and Antibacterial Activities of Novel 3-(Substituted Quinazolinylamino)-2-phenyl quinazolin-4(3H)ones." Asian Journal of Chemistry 32, no. 2 (2019): 281–86. http://dx.doi.org/10.14233/ajchem.2020.22280.

Full text

Abstract:

In the present study, we have synthesized a series of novel 2-phenyl-3-(substituted quinazolinylamino)quinazolin-4(3H)-ones by the reaction of 3-(substituted)-2-hydrazinoquinazoline-4(3H)-ones with 2-phenyl-3,1-benzoxazin-4-one. The starting material 3-(substituted)-2-hydrazinoquinazolin-4(3H)-ones were synthesized from various primary amines. All the synthesized compounds were screened for their antitubercular, anti-HIV and antibacterial activity against different Grampositive and Gram-negative strains by agar dilution method. Among the test compounds, 3-(4-nitrophenyl)-2-(4-oxo-2-phenylquina

APA, Harvard, Vancouver, ISO, and other styles

6

Azab, M. E., E. A. Kassab, M. A. El-Hashash, and R. S. Ali. "Synthesis and Antibacterial Activity of Some New 4(3H)Quinazolin-4-one Derivatives." Phosphorus, Sulfur, and Silicon and the Related Elements 184, no. 3 (2009): 610–25. http://dx.doi.org/10.1080/10426500802243182.

Full text

APA, Harvard, Vancouver, ISO, and other styles

7

Khan, Ayad Kareem. "Facile Synthesis, Characterization of New Quinazolinones with Different Azo Compounds, 1,2,3-Triazole Moieties and Evaluation Their Anti-bacterial Activity." Al-Mustansiriyah Journal of Science 28, no. 3 (2018): 122. http://dx.doi.org/10.23851/mjs.v28i3.180.

Full text

Abstract:

In the present research, a series of some azo compounds (5-9) and 1,2,3-triazoles derived from 2-methyl quinazolin-4(3H)-one were synthesized successfully by stepwise routes includes the following: 3-amino-2-methylquinazolin-4(3H)-one (3) prepared firstly by conversion of 2-aminobenzoic acid into methyl 2-aminobenzoate (1) followed by reaction with acetic anhydride to form methyl -2-acetamidobenzoate (2). The amide then allowed reacting with hydrazine hydrate to give compound (3). Diazotization reaction with sodium nitrite in the presence of hydrochloric acid yield the 3-(chlorodiazenyl)-2-met

APA, Harvard, Vancouver, ISO, and other styles

8

Debnath, Subal, and S. Y. Manjunath. "Conventional and Microwave Assisted Synthesis of 3-(Substituted)-2-phenyl quinazolin-4(3H)-one and their Antibacterial and Anthelmintic Activity." International Journal of Pharmaceutical Sciences and Nanotechnology 4, no. 2 (2011): 1408–11. http://dx.doi.org/10.37285/ijpsn.2011.4.2.6.

Full text

Abstract:

The present research work was aimed to synthesize a series of various substituted quinazolinone containing 3-(substituted)-2-phenylquinazolin-4(3H)-one. The compound 3-[(2-oxo-4-phenylazetidin-1-yl)-carbonyl]-2-phenylquinazolin-4(3H)-one, II was prepared by treating 4-oxo-2-phenyl-N-[(E)-phenylmethylidene]quinazoline-3(4H)-carboxamide, I with acetyl chloride and triethylamine (TEA) in benzene by conventional and microwave irradiation method. Synthesis of 3-[{2-oxo-3-(2,4-dichlorophenoxy)-4-phenylazetidin-carbonyl]-2-phenylquinazolin-4(3H)-one, III was carried out by reacting, I with 2,4-dichlo

APA, Harvard, Vancouver, ISO, and other styles

9

Masri, Abdulkader, Ayaz Anwar, Naveed Ahmed Khan, et al. "Antibacterial Effects of Quinazolin-4(3H)-One Functionalized-Conjugated Silver Nanoparticles." Antibiotics 8, no. 4 (2019): 179. http://dx.doi.org/10.3390/antibiotics8040179.

Full text

Abstract:

Infections due to multi-drug resistant bacteria are on the rise and there is an urgent need to develop new antibacterials. In this regard, a series of six functionally diverse new quinazolinone compounds were synthesized by a facile one-pot reaction of benzoic acid derivatives, trimethoxymethane and aniline derivatives. Three compounds of 3-aryl-8-methylquinazolin-4(3H)-one, and 3-aryl-6,7-dimethoxyquinazolin4(3H)-one were prepared and tested against multi-drug resistant bacteria. Furthermore, we determined whether conjugation with silver nanoparticles improved the antibacterial efficacy of th

APA, Harvard, Vancouver, ISO, and other styles

10

Charanjeet, Singh, Yaswant, and Sharma Mukesh. "SYNTHESIS AND ASSESSMENT THE IN-VITRO ANTIOXIDANT ACTIVITY OF 2,3-DISUBTITUTED QUINAZOLIN-4(3H)-ONE DERIVATIVES." International Journal of Current Pharmaceutical Review and Research 12, no. 2 (2020): 01–11. https://doi.org/10.5281/zenodo.12667459.

Full text

Abstract:

Quinazolinones have various biological activities such as anticancer, antibacterial,antidiabetic, anticonvulsant, antihistaminic, antiinflammatory, antifungal, anthelmintics andantiviral activities. In this research some of compounds 2,3-disubtituted quinazolin-4(3H)-one derivatives had been synthesized under microwave irradiation. The compounds wereobtained from reaction some of benzoxazine derivatives with hydrazine hydrate usingmicrowave irradiation and the result of reaction we obtained 82-96%. The products had beentested by IR, 1H-NMR, 13C-NMR and Mass Spectroscopy analysis. The using mic

APA, Harvard, Vancouver, ISO, and other styles

More sources

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!