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Journal articles on the topic 'Screened for antimicrobial activity'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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1

A., V. Dobaria, R. Patel J., and H. Parekh H. "Synthesis and antimicrobial screening of cyanopyridines." Journal of Indian Chemical Society Vol. 79, Sep 2002 (2002): 772–73. https://doi.org/10.5281/zenodo.5844555.

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Department of Chemistry, Saurashtra University, Rajkot-360 005, India <em>Fax : </em>91-0281-78512 <em>Manuscript received 3 May 2001, revised 5 November 2001, accepted 11 April 2002</em> 2-Amino-3-cyano-4-(2'-chloro-7'-methylquinolin-3'-y1)-6-arylpyridines (3a-n) have been synthesized by the condensation of chalcones (2a-n) with malononitrile and ammonium acetate. All the compounds have been screened for their antimicrobial activity.

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2

Mousumi, Bardhan, Purohit Pratigyan, S. Panda C., and Kumar Padhy Arun. "Antimicrobial activity of some pyridazinoquinoline derivatives." Journal of Indian Chemical Society Vol. 83, Jul 2006 (2006): 735–36. https://doi.org/10.5281/zenodo.5825346.

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Berhampur University, Berhampur-760 007, Orissa, India National Institute of Science & Technology, Palur Hills, Berhampur-761 008, Orissa, India E-mail: arun_nist@hotmail.com Manuscript received 17 August 2005, revised 29 March 2006, accepted 20 April 2006 Some pyridazinoquinoline derivatives have been synthesized and screened for their possible antimicrobial activity. Compound 1c exhibited significant activity against \(S\). \(aureus\), 1d and If exhibited significant activity against \(E\). \(coli\); whereas Ia and lb exhibited pronounced activity against fungi \(C\). \(albicana.\)

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3

M, Diwan, S. M. Verma, and Bandana. "Design, Synthesis and Evaluation of Some Potential Thiosemicarbazones as Antimicrobial Agents." International Journal of Drug Design and Discovery 3, no. 2 (2025): 766–71. https://doi.org/10.37285/ijddd.3.2.4.

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The newer Benzimidazolyl thiosemicarbazones were synthesized taken the lead from the earlier work of Dimmock and Pandeya with variation. Different aryl aldehydes and ketones were used for synthesis of various derivatives. The synthesized compounds were screened for antimicrobial activity against various bacteria and fungi. Among the compounds screened for antimicrobial activity compound 1 showed good antibacterial activity and compound 2 showed good antifungal activity.

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4

Liu, Yu Ting, Hai Long Guo, and Da Wei Yin. "Synthesis, Characterization and Antimicrobial Activity of Bis-Acetylferrocene Schiff Base." Advanced Materials Research 396-398 (November 2011): 1875–78. http://dx.doi.org/10.4028/www.scientific.net/amr.396-398.1875.

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Three bis-acetylferrocene schiff bases have been synthesized and characterized by IR, 1H NMR, and elemental analysis, the results conformed well with expected structures. The synthesized compounds were screened in vitro for their antimicrobial activity against three Gram-negative (Escherichia coli, Pseudomonas aeruginosa, and Salmonella typhi) and two Gram-positive (Bacillus subtilis and Staphylococcus aureus) bacterial strains. The results showed that these compounds are show excellent antimicrobia activities against Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi ,Bacillus subtili

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5

Dmitrii, A. Pisanenko, E. Klimko Yurii, V. Kostij Irina, N. Shunko Larisa, and L. Voljanskii Yurii. "Antimicrobial Activity of Some Halogenated Isoalkyl Phenols." Pharmaceutical and Chemical Journal 9, no. 1 (2022): 1–4. https://doi.org/10.5281/zenodo.13963857.

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Halogenated isopropyl-, sec-butyl-, sec-pentyl-, sec-hexyl, sec-heptylphenols were synthesized and screened for possible antibacterial and antifungal activities against <em>Staphylococcus aureus, Streptococcus viridans, Escherichia coli, Shigella flexneri, Salmonella typhi, Salmonella typhimurium, B. proteus vulgaris, Pseudomonas aeruginosa, Bacterium antracoides, Bacterium subtilis, Klebsiella rhinoscleuromatis</em> and <em>Candida albicans</em> using the microdilution method. Antimicrobial tests results indicated that all compounds have reasonable activity. They displayed the highest antimic

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6

Roy, R. U., A. R. R. Desai, and K. R. Desai. "Synthesis and Antimicrobial Activity of 1,2,4-Triazoles." E-Journal of Chemistry 2, no. 1 (2005): 1–5. http://dx.doi.org/10.1155/2005/843803.

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Several 3-(4'-nitrophenyl)-4-(4"-chloro benzamido)-5-substituted phenyl)-4H-1,2,4-triazole (3a-3e) and 3-(4'-nitrophenyl)-4-(4"-methyl benzenesulphonamido)-5-substituted phenyl)-4H-1,2,4-triazole (4a-4e) have been synthesised. Representative compounds were screened for antibacterial, antifungal activity. Most of them showed significant antibacterial activity.

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7

Karas, John A., Labell J. M. Wong, Olivia K. A. Paulin, et al. "The Antimicrobial Activity of Cannabinoids." Antibiotics 9, no. 7 (2020): 406. http://dx.doi.org/10.3390/antibiotics9070406.

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A post-antibiotic world is fast becoming a reality, given the rapid emergence of pathogens that are resistant to current drugs. Therefore, there is an urgent need to discover new classes of potent antimicrobial agents with novel modes of action. Cannabis sativa is an herbaceous plant that has been used for millennia for medicinal and recreational purposes. Its bioactivity is largely due to a class of compounds known as cannabinoids. Recently, these natural products and their analogs have been screened for their antimicrobial properties, in the quest to discover new anti-infective agents. This

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8

Hitesh, Kothari, and Singh Naruka Pushpendra. "Study of antimicrobial activity from plant extracts of Grewia abutilifolia." Pharmaceutical and Chemical Journal 9, no. 5 (2022): 11–19. https://doi.org/10.5281/zenodo.13973442.

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<em>Grewia abutilifolia</em> is a threatened medicinal plant having immense unexplored therapeutic activities. Four different types of extracts (Ethanolic extract, Petroleum ether soluble fraction, Chloroform soluble fraction and aqueous soluble fraction) of <em>Grewia abutilifolia </em>plant<em> </em>were prepared and evaluated for Preliminary phytochemical constituents. All the extracts were screened for antimicrobial activity against <em>Bacillus cereus</em>, <em>Staphylococcus aureus,</em> <em>Enterococcus faecalis</em>, <em>Escherichia coli</em>, <em>Pseudomonas aeruginosa, Salmonella ent

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9

Sravanthi, Chirra, Neelufar Shama S, Pranitha D, Madhav Reddy Ch, and Rao Jupally Venkateshwar. "Study of antimicrobial activity of novel Isatin derivatives." World Journal of Biology Pharmacy and Health Sciences 13, no. 1 (2023): 039–43. https://doi.org/10.5281/zenodo.7939816.

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<strong>Objective: </strong>The aim of this study to synthesize, characterize and screen some new isatin derivatives for their antimicrobial activities. <strong>Method:</strong> A library of isatin derivatives were synthesized, structures of newly synthesized compounds were deduced based on spectral data and elemental analysis. <strong>Results:</strong> Antibacterial activity was screened against gram positive and gram negative bacterial strains. <strong>Conclusion: </strong>The novel isatin derivatives produce significant antimicrobial activities.

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10

Leite, Sônia Pereira, Jeymesson Raphael Cardoso Vieira, Paloma Lys de Medeiros, et al. "Antimicrobial Activity of Indigofera suffruticosa." Evidence-Based Complementary and Alternative Medicine 3, no. 2 (2006): 261–65. http://dx.doi.org/10.1093/ecam/nel010.

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Various organic and aqueous extracts of leaves ofIndigofera suffruticosaMill (Fabaceae) obtained by infusion and maceration were screened for their antibacterial and antifungal activities. The extracts were tested against 5 different species of human pathogenic bacteria and 17 fungal strains by the agar-solid diffusion method. Most of the extracts were devoid of antifungal and antibacterial activities, except the aqueous extract of leaves ofI. suffruticosaobtained by infusion, which showed strong inhibitory activity against the Gram-positive bacteriaStaphylococcus aureuswith a minimal inhibito

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11

Pandya, Kruti, Bhavna Solanki, Bijal Shah, et al. "Phyto-chemical Screening & Evaluation of Antibacterial Activity of Polyherbal Formulation." Indo Global Journal of Pharmaceutical Sciences 01, no. 03 (2011): 206–18. http://dx.doi.org/10.35652/igjps.2011.20.

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Acnovin Capsule has a good amount of herbal ingredients that possess antimicrobial activity. They were screened to show their anti bacterial activity in three solvent extractions. They were also screened for the presence of pathogens, heavy metals and their Quality Control Parameters. All the ingredients have good activity on the skin. Few of the samples were also tested for their HPLC and HTLC charcaterization. © 2011 IGJPS. All rights reserved. Keywords: Antimicrobial activity, Mc Farland standard turbidity, Heavy metal analysis, Microbial analysis, HPLC, HPTLC.

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12

Smitha, Nair, P. Garg S., and Sah Pramilla. "Synthesis and antimicrobial activity of some new oxazolone derivatives of 4,5-disubstituted-2-aminothiazoles." Journal of Indian Chemical Society Vol. 83, Feb 2006 (2006): 205–7. https://doi.org/10.5281/zenodo.5817328.

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Department of Chemistry, J. N. V. University, Jodhpur-342 005. Rajasthan. India <em>Manuscript received 30 December 2004, revised 26 July 2005, accepted 31 October 2005</em> Some new 4-arylidene-2-(4'-(4",5" -disubstituted-2" -thiawlylaminol-3-nitrophcnyl)-4,5-dihydro-oxazolc-5-ones have been synthesized and screened for their antimicrobial activity.  

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13

D., A. Vyas, A. Chauhan N., and R. Parikh A. "Synthesis and antimicrobial activity of 2-substituted benzyl hydrazino-3-methyl quinoxalines." Journal of Indian Chemical Society Vol. 82, Nov 2005 (2005): 972–74. https://doi.org/10.5281/zenodo.5824654.

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Research & Development Centre, Indian Petrochemicals Corporation Ltd., Vadodara-391 345, India <em>E-mail</em> : dilipkumarvyas@yahoo.co.in Department of Chemistry, Saurashtra University, Rajkot-360 005, India <em>Fax</em>: 91-281-2578512 <em>Manuscript received 6 December 2004, revised 10 May 2005, accepted 25 July 2005</em> Reduction of 3-methyl-2-(arylidene hydrazino)quinoxalines 5a-l with NaBH<sub>4</sub> in controlled experimental conditions to give the 2- substituted benzyl hydrazine-3-methyl quinoxalines 6a-1 have been described. The structure of compounds 6a-1 have been confirmed f

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14

Vikash, Kumar, K. Roy R., Kumar Vipin, Kukshal Amit, and Prakash Yadav Ved. "Synthesis and antimicrobial activity of 2-(6-substituted-1,3-benzothiazol-2-yl)- N -( 4-halophenyl)hydrazinecarbothioamide." Journal of Indian Chemical Society Vol. 85, Mar 2008 (2008): 333–35. https://doi.org/10.5281/zenodo.5814696.

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or. K. N. Modi Institute of Pharmaceutical Education and Research, Modinagar-201 201, Uttar Pradesh, India <em>E-mail:</em> vikasruhilo1@yahoo.co.in, vikasruhii01 @rediffmail.com Department of Pharmaceutical Sciences, M. D. University, Rohtak-124 001, Haryana, India <em>Manuscript received 22 May 2007, revised 1 October 2007, accepted 26 November 2007</em> A number of new 2-(6-substituted-1,3-benzothiazol-2-yi)-<em>N</em>-(4-halophenyl)hydrazinecarbothioamidc (5a-o) have been synthesized and screened for antibacterial activity.

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15

Jadeja, Juvansinh, Mayank Mamtora, Mitesh B. Gondaliya, Rohit Manawar, and Manish K. Shah. "Synthesis, Spectral Analysis and Evolution of Antimicrobial Activity of Schiff Base of Cyanoacetohydrazide." International Letters of Chemistry, Physics and Astronomy 52 (June 2015): 100–110. http://dx.doi.org/10.18052/www.scipress.com/ilcpa.52.100.

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In search of some antimicrobial agents, synthesis of some Schiff base of cyanoacetohydrazide derivatives has been reported. The structures of all the synthesized compounds were established on the bases of various spectroscopic methods. All Schiff base were screened for antimicrobial activity. cyanoacetohydrazide were found to possess better antimicrobial potential.

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16

Jadeja, Juvansinh, Mayank Mamtora, Mitesh B. Gondaliya, Rohit Manawar, and Manish K. Shah. "Synthesis, Spectral Analysis and Evolution of Antimicrobial Activity of Schiff Base of Cyanoacetohydrazide." International Letters of Chemistry, Physics and Astronomy 52 (June 2, 2015): 100–110. http://dx.doi.org/10.56431/p-mrpq1z.

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In search of some antimicrobial agents, synthesis of some Schiff base of cyanoacetohydrazide derivatives has been reported. The structures of all the synthesized compounds were established on the bases of various spectroscopic methods. All Schiff base were screened for antimicrobial activity. cyanoacetohydrazide were found to possess better antimicrobial potential.

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17

Awujo, Nkem Chinedu, Musa Mu’azu Shahoro, and Alloysius Chibuike Ogodo. "Isolation and Screening of Bacteria with Antibiotic-producing Properties From the Soil at the Marmara and New Market Abattoirs, Wukari." Journal of Biochemistry, Microbiology and Biotechnology 12, no. 2 (2024): 33–36. https://doi.org/10.54987/jobimb.v12i2.1015.

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Antimicrobials are substances made by organisms that harm other organisms. Rising antibiotic resistance is a global issue, creating a need for alternative treatments. This study screened bacteria with antimicrobial properties from Marmara and New Market abattoirs in Wukari, Nigeria. Twelve soil samples were collected at each location from four sites: slaughtering, animal waste dumping, washing, and point of sale. Samples were taken at three soil depths: 0 cm, 10 cm, and 30 cm, totaling 24 samples. Isolates were screened and preliminarily identified using conventional methods. Eleven (11) bacte

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18

Fatma A M Mohamed, Fatma A. M. Mohamed, Bi Bi Zainab Mazhari Bi Bi Zainab Mazhari, Mona F. Warrad Mona F Warrad, Hesham A. M. Gomaa Hesham A M Gomaa, Asmaa T. Ali Asmaa T Ali, and Shaimaa Salah Eldeen Hussein and Hendawy Om Shaimaa Salah Eldeen Hussein and Hendawy Om. "Synthesis, Characterization, Antimicrobial and Anticarcinogenic Activity of Quinazoline Derivatives." Journal of the chemical society of pakistan 45, no. 3 (2023): 256. http://dx.doi.org/10.52568/001246/jcsp/45.03.2023.

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The reaction of β-dicarbonyl compounds as ethyl acetoacetate with hydrazines is a well-established route for the creation of pyrazole derivatives. In this research, 4-hydrazinoquinazoline (4) reacted with ethyl acetoacetate in boiling ethanol it gives ethyl 3-oxobutanoate quinazolin-4-yl-hydrazone (5). Cyclization of the compound (5) in the presence of glacial acetic acid is passed to form 4-(5-hydroxy-3-methyl-1H-pyrazol-1-yl)quinazoline(6). Furthermore, the reaction of phenylisothiocyanate compounds with hydrazines is a well-established way for the synthesis of tetrazinoquinazoline (8). The

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19

Mehta, Prakash, Prakash Davadra, Jalpa R. Pandya, and Hitendra S. Joshi. "Synthesis, Characterization and Antimicrobial Activity of 2-Azetidinone Derivatives of Benzimidazoles." International Letters of Chemistry, Physics and Astronomy 30 (March 2014): 81–88. http://dx.doi.org/10.18052/www.scipress.com/ilcpa.30.81.

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Some new 2-azetidinone derivatives possessing benzimidazole nucleus were synthesized and characterized by IR, NMR and mass spectral analysis. All synthesized compounds were screened for antimicrobial activity using cup plate method. All the compounds showed moderate to good antimicrobial activity and anti fungal activity.

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20

Mehta, Prakash, Prakash Davadra, Jalpa R. Pandya, and Hitendra S. Joshi. "Synthesis, Characterization and Antimicrobial Activity of 2-Azetidinone Derivatives of Benzimidazoles." International Letters of Chemistry, Physics and Astronomy 30 (March 12, 2014): 81–88. http://dx.doi.org/10.56431/p-sf5m81.

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Some new 2-azetidinone derivatives possessing benzimidazole nucleus were synthesized and characterized by IR, NMR and mass spectral analysis. All synthesized compounds were screened for antimicrobial activity using cup plate method. All the compounds showed moderate to good antimicrobial activity and anti fungal activity.

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21

Torres, Nelson S., Johnathan J. Abercrombie, Anand Srinivasan, Jose L. Lopez-Ribot, Anand K. Ramasubramanian, and Kai P. Leung. "Screening a Commercial Library of Pharmacologically Active Small Molecules against Staphylococcus aureus Biofilms." Antimicrobial Agents and Chemotherapy 60, no. 10 (2016): 5663–72. http://dx.doi.org/10.1128/aac.00377-16.

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ABSTRACTIt is now well established that bacterial infections are often associated with biofilm phenotypes that demonstrate increased resistance to common antimicrobials. Further, due to the collective attrition of new antibiotic development programs by the pharmaceutical industries, drug repurposing is an attractive alternative. In this work, we screened 1,280 existing commercially available drugs in the Prestwick Chemical Library, some with previously unknown antimicrobial activity, againstStaphylococcus aureus, one of the commonly encountered causative pathogens of burn and wound infections.

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22

Rajashree, Markandewar1 Hanfi Mohd. Ziauddin2 M.A.Baseer2. "NOVEL PYRAZOLINES DERIVED FROM PIPERAZINE CHALCONES SYNTHESIS ANTIMICROBIAL STUDIES." INDO AMERICAN JOURNAL OF PHARMACEUTICAL RESEARCH 07, no. 01 (2017): 7348–52. https://doi.org/10.5281/zenodo.1005172.

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In pursuit to synthesize the molecules of biological interest we reported here the synthesis of some novel pyrazolines from piperazine chalcones under basic condition using hydrazine hydrate. Ethanol is used as a solvent medium for the reaction. These newly synthesized pyrazolines are screened for antimicrobial studies and showed moderate to good activity.

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23

G., C. KAMDAR, PAREKH HANSA, and R. PARIKH A. "Preparation ans Antimicrobial Activity of 4-Aryl-3-)(phenazon-4'-yl)sydnonimine Hydrochloride." Journal of Indian Chemical Society Vol. 64, Jul 1987 (1987): 420–21. https://doi.org/10.5281/zenodo.6196153.

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Department of Chemistry, Saurashtra University, Rajkot-360 005 <em>Manuscript received 16 June 1983, revised 9 March 1987, accepted 22 April 1987</em> 4-Aryl-3-(phenazon-4'-yl)sydnonimine hydrochloride have been prepared by the treatment of 4-(4.-cyanobenzylamino)phenazone with nitrous acid and methanolic hydrochloric acid. Th e constitution was supported by ir spectra. The products were screened for antibacterial activity.

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24

Kaul, Ankur, Anjani K. Tiwari, Raunak Varshney, and Anil K. Mishra. "Synthesis, in silico screening and preclinical evaluation studies of a hexapeptide analogue for its antimicrobial efficacy." RSC Advances 5, no. 118 (2015): 97180–86. http://dx.doi.org/10.1039/c5ra14936c.

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25

Dmitrii, A. Pisanenko, E. Klimko Yurii, and L. Voljanskii Yurii. "Synthesis and antimicrobial activity of some halogenated isopentyl phenols." Chemistry Research Journal 2, no. 2 (2017): 23–27. https://doi.org/10.5281/zenodo.13956199.

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Some halogenated isopentyl phenols were synthesized and screened for possible antibacterial and antifungal activities against <em>Staphylococcus aureus, Streptococcus viridans, Escherichia coli, Shigella flexneri, Salmonella typhi, Salmonella typhimurium, B.proteus vulgaris, Pseudomonas aeruginosa, Bacterium antracoides, Bacterium subtilis, Klebsiella rhinoscleuromatis and Candida albicans</em> using the microdilution method. Antimicrobial tests results indicated that all compounds have reasonable activity. They displayed the highest antimicrobial activity against <em>Streptococcus aureus</em>

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26

Vekariya, Piyush B., Jalpa R. Pandya, Vaishali Goswami, and Hitendra S. Joshi. "Synthesis and Biological Activity of 1,2,4-Triazolo-[3,4-b]Thiadiazole as Antimicrobial Agents." International Letters of Chemistry, Physics and Astronomy 26 (January 2014): 45–52. http://dx.doi.org/10.18052/www.scipress.com/ilcpa.26.45.

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Some novel 6-fluoro chroman derivatives having 1,2,4-triazolo-[3,4-b]thiadiazole were synthesized and characterized by IR, NMR and mass spectral analysis. All synthesized compounds were screened for antimicrobial activity using broth dilution method. All the compounds showed good antimicrobial activity and compound 5e showed significant antibacterial activity.

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27

Makwana, Hitesh, and Yogesh T. Naliapara. "Synthesis, Characterization and Antimicrobial Activity of N’-Benzylidene-5-Bromothiophene-2-Carbohydrazide Derivatives." International Letters of Chemistry, Physics and Astronomy 33 (May 2014): 99–105. http://dx.doi.org/10.18052/www.scipress.com/ilcpa.33.99.

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Some new N’-benzylidene-5-bromothiophene-2-carbohydrazide derivatives possessing thiophene nucleus were synthesized and characterized by IR, NMR and mass spectral analysis. All synthesized compounds were screened for antimicrobial activity using cup plate method. All the compounds showed moderate to good antimicrobial activity and anti fungal activity

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28

Makwana, Hitesh, and Yogesh T. Naliapara. "Synthesis, Characterization and Antimicrobial Activity of N’-Benzylidene-5-Bromothiophene-2-Carbohydrazide Derivatives." International Letters of Chemistry, Physics and Astronomy 33 (May 11, 2014): 99–105. http://dx.doi.org/10.56431/p-dzucwt.

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Some new N’-benzylidene-5-bromothiophene-2-carbohydrazide derivatives possessing thiophene nucleus were synthesized and characterized by IR, NMR and mass spectral analysis. All synthesized compounds were screened for antimicrobial activity using cup plate method. All the compounds showed moderate to good antimicrobial activity and anti fungal activity

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29

Vekariya, Piyush B., Jalpa R. Pandya, Vaishali Goswami, and Hitendra S. Joshi. "Synthesis and Biological Activity of 1,2,4-Triazolo-[3,4-b]Thiadiazole as Antimicrobial Agents." International Letters of Chemistry, Physics and Astronomy 26 (January 24, 2014): 45–52. http://dx.doi.org/10.56431/p-t014h3.

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Some novel 6-fluoro chroman derivatives having 1,2,4-triazolo-[3,4-b]thiadiazole were synthesized and characterized by IR, NMR and mass spectral analysis. All synthesized compounds were screened for antimicrobial activity using broth dilution method. All the compounds showed good antimicrobial activity and compound 5e showed significant antibacterial activity.

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30

Marjadi, S. I., J. H. Solanki, and A. L. Patel. "Synthesis and Antimicrobial Activity of Some New Formazan Derivatives." E-Journal of Chemistry 6, no. 3 (2009): 844–48. http://dx.doi.org/10.1155/2009/456195.

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A series of new substituted formazan derivatives has been synthesized from corresponding aryl diazonium chloride and Schiff base in pyridine. The synthesized compounds were identified by spectral studies and screened for their antimicrobial activities.

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31

Badgujar, D. M., M. B. Talawar, and P. P. Mahulikar. "Biological Evaluation of 1, 2-bis (2, 4, 6-Trinitrophenyl) Hydrazine." Indian Journal of Pharmaceutical and Biological Research 1, no. 04 (2013): 25–29. http://dx.doi.org/10.30750/ijpbr.1.4.5.

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1, 2-Bis (2, 4, 6-trinitrophenyl) hydrazine (3) and its precursor (2) were screened for its antimicrobial properties, namely, antifungal activity against Aspergilus niger and Alternaria aletrnata and antibacterial activity against Bacillus substalis and Xanthomonas campstris at different concentrations (0.5 % and 1%). The antimicrobial result exhibits the promising biological activity.

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32

Ali Mustafa, Ahmed, та Haifa A. A. Omer. "تقييم مضادات الميكروبات مضادات الأكسدة والمحتوى الكلي للفينولات لمستخلصات السنا سنا في السودان". Omdurman Islamic University Journal 20, № 1 (2024): 10–18. http://dx.doi.org/10.52981/oiuj.v20i1.3101.

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The objective of the present study was the assessment of the antimicrobial and antioxidant activities of Senna italic., from n-hexane, chloroform, ethyl acetate and methanol extracts. In addition, the total polyphenol, flavonoids and tannins contents of these extracts were determined and; were screened for their antimicrobial activity using cup diffusion assay against four standard strains of bacteria, two Gram-positive strains (Bacillus subtitles and Staphylococcus aurous), two Gram-negative bacterial strains (Escherichia coli and Pseudomonas aeruginosa) and two fungal strains (Aspergillums N

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33

Shweta, Tiwari, Kirar Seema, Chand Banerjee Uttam, Kishore Babu Neerupudi, Singh Sushma, and Pal Singh Inder. "Synthesis and biological evaluation of quinoline-quinazolinones for antimicrobial and antileishmanial potential." Journal of Indian Chemical Society Vol. 97, Aug 2020 (2020): 1251–58. https://doi.org/10.5281/zenodo.5656647.

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Department of Natural Products, bDepartment of Pharmaceutical Technology Biotechnology, Department of Biotechnology, National Institute of Pharmaceutical Education and Research (NIPER), Sector-67, S.A.S. Nagar-160 062, Punjab, India <em>E-mail</em>: ipsingh@niper.ac.in, ipsingh67@yahoo.com <em>Manuscript received online 03 July 2020, accepted 30 July 2020</em> In an attempt to find a new class of antimicrobial and antileishmanial agents, a series of twenty-three quinoline-quinazolinones were prepared via reaction of 8-hydroxy/methoxyquinoline-2-carbaldehyde with various substituted aminobenzam

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34

Kumar, Sahil, Rakesh Narang, Manish Devgun, and Sukhbir Lal. "ANTIMICROBIAL ACTIVITY AND SAR OF 2,5-DISUBSTITUTED 1,3,4-OXADIAZOLE DERIVATIVES." Journal of Advanced Scientific Research 13, no. 01 (2022): 1–22. http://dx.doi.org/10.55218/jasr.202213101.

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1,3,4-oxadiazole is a five membered heterocyclic aromatic moiety, present in a number of antimicrobial agents. 2,5- disubstituted 1,3,4-oxadiazole derivatives have shown broad spectrum of antibacterial and antifungal activities. Many scientific groups have synthesized and screened their antimicrobial potential. Reported activity data showed that some 1,3,4-oxadiazole derivatives exhibited better activity than already known antibiotics. Hence, they can be used as lead for development of promising antimicrobial agents. In present review, antimicrobial activities and SAR of 2,5-disubstituted 1,3,

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35

Waghulde, Sandeep, Nilofar Abid Khan, Nilesh Gorde, Mohan Kale, Pravin Naik, and Rupali Prashant Yewale. "Comparative Antimicrobial Activity Study of Brassica oleceracea." Proceedings 9, no. 1 (2018): 64. http://dx.doi.org/10.3390/ecsoc-22-05662.

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Medicinal plants are in rich source of antimicrobial agents. The present study was carried out to evaluate the antimicrobial effect of plants from the same species as Brassica oleceracea namely, white cabbage and red cabbage. The preliminary phytochemical analysis was tested by using a different extract of these plants for the presence of various secondary metabolites like alkaloids, flavonoids, tannins, saponins, terpenoids, glycosides, steroids, carbohydrates, and amino acids. The in vitro antimicrobial activity was screened against clinical isolates viz gram positive bacteria Staphylococcus

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R., H. Udupi, M. Kulkarni V., Purushottamachar P., and Srinivasalu N. "Synthesis and biological screening of bridgehead nitrogen heterocycles: reactions of 4-(N-pyridylcarboxamido)- 5-mercapto-3-substituted -1 ,2,4-triazoles." Journal of India Chemical Society Vol. 79, Apr 2002 (2002): 381–82. https://doi.org/10.5281/zenodo.5849558.

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Department of Pharmaceutical Chemistry, V. L. College of Pharmacy, Raichur-584 101, India <em>E-mail</em> : neeladris@rediffmail.com Pharmaceuticals Division, Department of Chemical Technology, University of Mumbai, Matunga. Mumbai-400 019, India <em>Manuscript received 5 June 2000 revised 22 August 2001, accepted 25 September 2001</em> Some 6,7-diphenyl-3,5-disubstituted-<em>s</em>-triazolo[3,4-<em>b</em>][1,3,4]thiadiazines and 3,4-disubstituted-7 (<em>H</em>)-<em>s</em>-triazolo[3,4-b)[1 ,3,4]thiadiazinones have been prepared and screened for antimicrobial activity.

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LINA, MEHTA, and PAREKH HANSA. "Studies on 4-Thiazolidinones. Part-V. Synthesis and Antimicrobial Activity of 2-Aryl-3(2',4'-diphenylamino-s- triazin-6'-yl)-5-H/ methy / carboxymethyl-4-thiazolidinones." Journal of Indian Chemical Society Vol. 65, Sep 1988 (1988): 648–50. https://doi.org/10.5281/zenodo.6043069.

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Department of Chemistry, Saurashtra University, Rajkot-360 005 <em>Manuscript received 18 January 1988, revised 5 May 1988, accepted 6 July 1988</em> Several new 4-thiazolidinone derivatives were prepared bearing 2,4- diphenylamino-6-amino-<em>s</em>-triazine moiety. Their structures were supported by ir and mass spectral study. The products were screened for antimicrobial activity.

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Kussmann, Manuel, Markus Obermueller, Kathrin Spettel, Stefan Winkler, and Daniel Aletaha. "In vitro evaluation of disease-modifying antirheumatic drugs against rheumatoid arthritis associated pathogens of the oral microflora." RMD Open 7, no. 3 (2021): e001737. http://dx.doi.org/10.1136/rmdopen-2021-001737.

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ObjectivesIn the past, the human microbiome has consistently been associated with rheumatoid arthritis (RA) and disease activity. Here, we investigate the antimicrobial activity of disease-modifying antirheumatic drugs (DMARDs) against typical representatives of the oral microflora that have been associated with RA.MethodsDMARDs were screened for antimicrobial activity against bacteria that are associated with the pathogenesis of the disease and/or frequently isolated from the oral microflora of patients with RA. Screening was done by an agar diffusion assay and minimum inhibitory concentratio

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Baviskar, B. A., Bhagyesh Baviskar, M. R. Shiradkar, U. A. Deokate, and S. S. Khadabadi. "Synthesis and Antimicrobial Activity of SomeNovel Benzimidazolyl Chalcones." E-Journal of Chemistry 6, no. 1 (2009): 196–200. http://dx.doi.org/10.1155/2009/746292.

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Some novel benzimidazolyl chalcones were synthesized by condensation ofN-(4-(1H-benzo[d]imidazol-2-yl)phenyl)acetamide with aromatic aldehydes in presence of aqueous potassium hydroxide solution at room temperature. All the synthesized compounds were characterized on the basis of their IR,1H NMR spectroscopic data and elemental analysis. All the compounds have been screened for antimicrobial activity by the cup-plate method.

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Aminin, Agustina L. N., Nur Cahyanti, Alfina Sari, Nies Suci Mulyani, and Bambang Cahyono. "Antioxidant and Antimicrobial Screening of Endophytic Fungi Culture Filtrate from Purwoceng (Pimpinella alpina Molk) Leaf." Jurnal Kimia Sains dan Aplikasi 23, no. 9 (2020): 319–24. http://dx.doi.org/10.14710/jksa.23.9.319-324.

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This is a preliminary study to determine the bioactivity potential of purwoceng leaf endophytic fungal metabolites. Endophytic fungi were isolated from purwoceng leaf and their secondary metabolite from culture filtrate were subjected to identify the antimicrobial, antioxidant, and phytochemical screening. The antioxidant activity was screened by scavenging 2,2-diphenyl-1-picrylhydrazyl (DPPH). The antimicrobial activity was screened using a good agar method toward Salmonella typhi, Escherichia coli, Bacillus subtilis, Staphylococcus aureus, dan Candida albicans. This study obtained five disti

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Bhat, Mashooq Ahmad, Mohamed A. Al-Omar, Ahmed M. Naglah, and Abdul Arif Khan. "Enaminone-Derived Pyrazoles with Antimicrobial Activity." Journal of Chemistry 2019 (November 7, 2019): 1–10. http://dx.doi.org/10.1155/2019/2467970.

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A series of pyrazoles derived from the substituted enaminones were synthesized and were evaluated for antimicrobial activity. All the compounds were characterized by the spectral data and elemental analysis. The synthesized compounds were initially screened for their antimicrobial activity against ATCC 6538, NCTC 10400, NCTC 10418, and ATCC 27853. During initial screening, compounds (P1, P6, and P11) presented significant antimicrobial activity through disc diffusion assay. These compounds were further evaluated for antimicrobial activity at different time points against Gram-positive and Gram

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Jeganathan, P., K. M. Rajasekaran, N. K. Asha Devi, and S. Karuppusamy. "Antimicrobial activity and Characterization of Marine bacteria." Indian Journal of Pharmaceutical and Biological Research 1, no. 04 (2013): 38–44. http://dx.doi.org/10.30750/ijpbr.1.4.8.

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Marine bacteria were isolated from seawater was collected from different coastal areas of the Tamilnadu Sea. The antimicrobial activities of these bacteria were investigated. Ethyl acetate extracts of marine bacterial fermentation were screened for antimicrobial activities using the method of agar diffusion. The results showed that 25 strains of the isolates have antimicrobial activity. The proportion of active bacteria associated with isolated from seawater. The active marine bacteria were assigned to the genera Alteromonas, Pseudomonas, Bacillus and Marinobacter. The TLC autobiographic overl

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Gothwal, Priya, Gunwanti Malhotra, and Y. K. Srivastava. "Microwave Assisted Synthesis and Antimicrobial Activities of Some 2-Amino-4-aryl-3-cyano-6-(4’-hydroxy phenyl)-pyridines." E-Journal of Chemistry 8, no. 1 (2011): 119–22. http://dx.doi.org/10.1155/2011/984297.

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4’-Hydroxy chalcones were treated with malononitrile in the presence of ammonium acetate under solventless microwave assisted condition to get 2-amino-4-aryl-3-cyano-6-(4’-hydroxy phenyl)-pyridines. The prepared compounds were screened for their antimicrobial activity; some of them have exhibited promising antimicrobial activity.

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Kwansa-Bentum, Bethel, Beatrice Awuradwoa Okine, Alberta D. Dayie, et al. "In Vitro effects of petroleum ether, dichloromethane, methanolic and aqueous leaf extracts of Eucalyptus grandis on selected multidrug-resistant bacteria." PLOS ONE 18, no. 3 (2023): e0283706. http://dx.doi.org/10.1371/journal.pone.0283706.

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Background The emergence and spread of antimicrobial resistance is of grave concern, requiring the search for newer and more effective antimicrobials to combat infections caused by resistant microbes. This study assessed the antimicrobial effects of Eucalyptus grandis crude extracts against selected multidrug resistant bacteria. Methodology Four different crude leaf extracts of E. grandis were prepared using petroleum ether, dichloromethane, methanol, and water, with the aid of the Soxhlet extraction method. These were screened against methicillin-resistant Staphylococcus aureus (MRSA), multid

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Rohmatussolihat, Rohmatussolihat, Puspita Lisdiyanti, Yopi Yopi, Yantyati Widyastuti, and Endang Sukara. "Medium Optimization for Antimicrobial Production By Newly Screened Lactic Acid Bacteria." ANNALES BOGORIENSES 22, no. 1 (2018): 1. http://dx.doi.org/10.14203/ab.v22i1.322.

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Lactic acid bacteria (LAB) are important for prevention of spoilage and pathogenic bacterial growth in foods due to their ability to generate antimicrobial substances. The objective of this study was to screen LAB for antimicrobial activity and to optimize culture medium for antimicrobial production using Response Surface Methodology (RSM) with Central Composite Design (CCD). Optimization of antimicrobial production of selected LAB was conducted with different combinations of glucose, NaCl, inoculum, and temperature. Our experimental results showed that from 129 LAB isolates, 55 showed signifi

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Rohmatussolihat, Rohmatussolihat, Puspita Lisdiyanti, Yopi Yopi, Yantyati Widyastuti, and Endang Sukara. "Medium Optimization for Antimicrobial Production By Newly Screened Lactic Acid Bacteria." ANNALES BOGORIENSES 22, no. 1 (2018): 1. http://dx.doi.org/10.14203/ann.bogor.2018.v22.n1.1-11.

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Lactic acid bacteria (LAB) are important for prevention of spoilage and pathogenic bacterial growth in foods due to their ability to generate antimicrobial substances. The objective of this study was to screen LAB for antimicrobial activity and to optimize culture medium for antimicrobial production using Response Surface Methodology (RSM) with Central Composite Design (CCD). Optimization of antimicrobial production of selected LAB was conducted with different combinations of glucose, NaCl, inoculum, and temperature. Our experimental results showed that from 129 LAB isolates, 55 showed signifi

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Jajere, U. M., M. Mohammed, H. Nuhu, and A. Anas. "Preliminary Phytochemical Screening and Antimicrobial Activity of the Methanol Fractions of the Leaf of Gmelina arborea (Verbenaceae)." Bayero Journal of Pure and Applied Sciences 14, no. 2 (2022): 125–33. http://dx.doi.org/10.4314/bajopas.v14i2.15.

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Leaves of Gmelina arborea are used in traditional medicine for the treatment of bacterial infections without scientific validations. The main objective of the research was to carry out preliminary phytochemical and antimicrobial screening of the methanol fractions of the leaf of Gmelina arborea. The methanol leaf extract and its fractions were screened for phytochemical and antimicrobial activity using standard procedures. Preliminary phytochemical screening revealed the presence of alkaloids, flavonoids, saponins, phenolic compounds, triterpenes and steroids. Highest zone of inhibition was ob

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Segundo, Walter Oliva Pinto Filho, Roberta Silva de Oliveira, Rildo Mendes Lima, et al. "Antimicrobial Potential of Metabolites in Fungal Strains Isolated from a Polluted Stream: Annulohypoxylon stygium WL1B5 Produces Metabolites against Extended-Spectrum Beta-Lactamase-Positive Escherichia coli." Antibiotics 12, no. 1 (2022): 27. http://dx.doi.org/10.3390/antibiotics12010027.

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The emergence of multidrug resistance in bacterial pathogens is a growing public health concern requiring solutions including the discovery of new antimicrobial drugs. Fungi have been used for decades as a source of antimicrobials. Ongoing screenings for newly characterized fungal strains producing antimicrobials include environments that are difficult to access like the deep sea, glaciers, wastewaters and environments polluted due to human activity. In the present study, fungal microorganisms were isolated from water samples taken from a polluted stream in the city of Manaus, AM, Brazil, and

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Hbibi, Abdelhadi, Khadija Sikkou, Khadija Khedid, Sakina El Hamzaoui, Amal Bouziane, and Driss Benazza. "Antimicrobial activity of honey in periodontal disease: a systematic review." Journal of Antimicrobial Chemotherapy 75, no. 4 (2020): 807–26. http://dx.doi.org/10.1093/jac/dkz527.

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Abstract Background Honey has shown positive antimicrobial and anti-inflammatory actions in several dermatological studies; however, it is unclear if it could be effective in the treatment of periodontal disease. Objectives To answer the question: Does honey have antimicrobial activity against periodontopathogens? Methods Six electronic databases were screened from initiation to 31 January 2019 for randomized clinical trials (RCTs) and controlled in vitro studies exploring the antimicrobial effect of honey against periodontopathogens. Honey’s botanical origin, periopathogens that showed microb

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D., BHASKAR REDDY, SESHAMMA T., REDDY S., and V. RAMANA REDDY M. "Synthesis and Bioactive Nature of some New Bis(2-pyrazolin-3-yl) benzenes. Part-II." Journal of Indian Chemical Society Vol. 68, May 1991 (1991): 281–84. https://doi.org/10.5281/zenodo.5992418.

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Department of Chemistry, S. V. University, Tirupati-517 562 The Wistar Institute of Anatomy and Biology, 36th Street at Spruce, Philadelphia, PA 19104, U.S.A. <em>Manuscript received 10 April 1990, revised 19 October 1990, accepted 23 April 1991</em> Cycloaddition or diazomethane to 3,3'-(1,3- and 1,4-phenylene)bis(1-aryl-2-propen-1-ones) (3) at- 20° in presence of triethylamine gave the title compounds (4). Their <em>N</em>-substituted derivatives (5-7) have been obtained by nitrosation, benzoylation and benzenesulphonylation. The compounds 4 have been screened for antimicrobial

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