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1

Tang, Dan, Jingwen Sheng, Liangting Xu, et al. "Cryo-EM structure of C9ORF72–SMCR8–WDR41 reveals the role as a GAP for Rab8a and Rab11a." Proceedings of the National Academy of Sciences 117, no. 18 (2020): 9876–83. http://dx.doi.org/10.1073/pnas.2002110117.

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A massive intronic hexanucleotide repeat (GGGGCC) expansion in C9ORF72 is a genetic origin of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Recently, C9ORF72, together with SMCR8 and WDR41, has been shown to regulate autophagy and function as Rab GEF. However, the precise function of C9ORF72 remains unclear. Here, we report the cryogenic electron microscopy (cryo-EM) structure of the human C9ORF72–SMCR8–WDR41 complex at a resolution of 3.2 Å. The structure reveals the dimeric assembly of a heterotrimer of C9ORF72–SMCR8–WDR41. Notably, the C-terminal tail of C9ORF72 and
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2

McAlpine, William, Lei Sun, Kuan-wen Wang, et al. "Excessive endosomal TLR signaling causes inflammatory disease in mice with defective SMCR8-WDR41-C9ORF72 complex function." Proceedings of the National Academy of Sciences 115, no. 49 (2018): E11523—E11531. http://dx.doi.org/10.1073/pnas.1814753115.

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The SMCR8-WDR41-C9ORF72 complex is a regulator of autophagy and lysosomal function. Autoimmunity and inflammatory disease have been ascribed to loss-of-function mutations of Smcr8 or C9orf72 in mice. In humans, autoimmunity has been reported to precede amyotrophic lateral sclerosis caused by mutations of C9ORF72. However, the cellular and molecular mechanisms underlying autoimmunity and inflammation caused by C9ORF72 or SMCR8 deficiencies remain unknown. Here, we show that splenomegaly, lymphadenopathy, and activated circulating T cells observed in Smcr8−/− mice were rescued by triple knockout
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3

Liang, Chen, Qiang Shao, Wei Zhang, et al. "Smcr8 deficiency disrupts axonal transport-dependent lysosomal function and promotes axonal swellings and gain of toxicity in C9ALS/FTD mouse models." Human Molecular Genetics 28, no. 23 (2019): 3940–53. http://dx.doi.org/10.1093/hmg/ddz230.

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Abstract G4C2 repeat expansions in an intron of C9ORF72 cause the most common familial amyotrophic lateral sclerosis and frontotemporal dementia (collectively, C9ALS/FTD). Mechanisms and mediators of C9ALS/FTD pathogenesis remain poorly understood. C9orf72 and Smcr8 form a protein complex. Here, we show that expression of Smcr8, like C9orf72, is reduced in C9ALS/FTD mouse models and patient tissues. Since Smcr8 is highly conserved between human and mouse, we evaluated the effects of Smcr8 downregulation in mice. Smcr8 knockout (KO) mice exhibited motor behavior deficits, which resemble those o
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4

Nörpel, Julia, Simone Cavadini, Andreas D. Schenk, et al. "Structure of the human C9orf72-SMCR8 complex reveals a multivalent protein interaction architecture." PLOS Biology 19, no. 7 (2021): e3001344. http://dx.doi.org/10.1371/journal.pbio.3001344.

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A major cause of familial amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) spectrum disorder is the hexanucleotide G4C2 repeat expansion in the first intron of the C9orf72 gene. Many underlying mechanisms lead to manifestation of disease that include toxic gain-of-function by repeat G4C2 RNAs, dipeptide repeat proteins, and a reduction of the C9orf72 gene product. The C9orf72 protein interacts with SMCR8 and WDR41 to form a trimeric complex and regulates multiple cellular pathways including autophagy. Here, we report the structure of the C9orf72-SMCR8 complex at 3.8 Å reso
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5

Yang, Mei, Chen Liang, Kunchithapadam Swaminathan, et al. "A C9ORF72/SMCR8-containing complex regulates ULK1 and plays a dual role in autophagy." Science Advances 2, no. 9 (2016): e1601167. http://dx.doi.org/10.1126/sciadv.1601167.

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The intronic GGGGCC hexanucleotide repeat expansion in chromosome 9 open reading frame 72 (C9ORF72) is a prevalent genetic abnormality identified in both frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS). Smith-Magenis syndrome chromosomal region candidate gene 8 (SMCR8) is a protein with unclear functions. We report that C9ORF72 is a component of a multiprotein complex containing SMCR8, WDR41, and ATG101 (an important regulator of autophagy). The C9ORF72 complex displays guanosine triphosphatase (GTPase) activity and acts as a guanosine diphosphate–guanosine 5′-triphosphat
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6

Amick, Joseph, Agnes Roczniak-Ferguson, and Shawn M. Ferguson. "C9orf72 binds SMCR8, localizes to lysosomes, and regulates mTORC1 signaling." Molecular Biology of the Cell 27, no. 20 (2016): 3040–51. http://dx.doi.org/10.1091/mbc.e16-01-0003.

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Hexanucleotide expansion in an intron of the C9orf72 gene causes amyotrophic lateral sclerosis and frontotemporal dementia. However, beyond bioinformatics predictions that suggested structural similarity to folliculin, the Birt-Hogg-Dubé syndrome tumor suppressor, little is known about the normal functions of the C9orf72 protein. To address this problem, we used genome-editing strategies to investigate C9orf72 interactions, subcellular localization, and knockout (KO) phenotypes. We found that C9orf72 robustly interacts with SMCR8 (a protein of previously unknown function). We also observed tha
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7

Jung, Jennifer, and Christian Behrends. "Multifaceted role of SMCR8 as autophagy regulator." Small GTPases 11, no. 1 (2017): 53–61. http://dx.doi.org/10.1080/21541248.2017.1346553.

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8

Talaia, Gabriel, Joseph Amick, and Shawn M. Ferguson. "Receptor-like role for PQLC2 amino acid transporter in the lysosomal sensing of cationic amino acids." Proceedings of the National Academy of Sciences 118, no. 8 (2021): e2014941118. http://dx.doi.org/10.1073/pnas.2014941118.

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PQLC2, a lysosomal cationic amino acid transporter, also serves as a sensor that responds to scarcity of its substrates by recruiting a protein complex composed of C9orf72, SMCR8, and WDR41 to the surface of lysosomes. This protein complex controls multiple aspects of lysosome function. Although it is known that this response to changes in cationic amino acid availability depends on an interaction between PQLC2 and WDR41, the underlying mechanism for the regulated interaction is not known. In this study, we present evidence that the WDR41–PQLC2 interaction is mediated by a short peptide motif
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9

Zhao, Shidong, Wenwen Ru, Xinyan Chen, et al. "Structural insights into SMCR8 C-degron recognition by FEM1B." Biochemical and Biophysical Research Communications 557 (June 2021): 236–39. http://dx.doi.org/10.1016/j.bbrc.2021.04.046.

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10

Kumar, Vijay. "Molecular interactions between C9ORF72 and SMCR8: A local energetic frustration perspective." Biochemical and Biophysical Research Communications 570 (September 2021): 1–7. http://dx.doi.org/10.1016/j.bbrc.2021.07.016.

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11

Tang, Dan, Jingwen Sheng, Liangting Xu, Chuangye Yan, and Shiqian Qi. "The C9orf72-SMCR8-WDR41 complex is a GAP for small GTPases." Autophagy 16, no. 8 (2020): 1542–43. http://dx.doi.org/10.1080/15548627.2020.1779473.

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12

Fukatsu, Shoya, Hinami Sashi, Remina Shirai, et al. "Rab11a Controls Cell Shape via C9orf72 Protein: Possible Relationships to Frontotemporal Dementia/Amyotrophic Lateral Sclerosis (FTDALS) Type 1." Pathophysiology 31, no. 1 (2024): 100–116. http://dx.doi.org/10.3390/pathophysiology31010008.

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Abnormal nucleotide insertions of C9orf72, which forms a complex with Smith–Magenis syndrome chromosomal region candidate gene 8 (SMCR8) protein and WD repeat-containing protein 41 (WDR41) protein, are associated with an autosomal-dominant neurodegenerative frontotemporal dementia and/or amyotrophic lateral sclerosis type 1 (FTDALS1). The differentially expressed in normal and neoplastic cells (DENN) domain-containing C9orf72 and its complex with SMCR8 and WDR41 function as a guanine-nucleotide exchange factor for Rab GTP/GDP-binding proteins (Rab GEF, also called Rab activator). Among Rab pro
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13

Lan, Yungang, Peter M. Sullivan, and Fenghua Hu. "SMCR8 negatively regulates AKT and MTORC1 signaling to modulate lysosome biogenesis and tissue homeostasis." Autophagy 15, no. 5 (2019): 871–85. http://dx.doi.org/10.1080/15548627.2019.1569914.

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14

Zhang, Yingying, Aaron Burberry, Jin-Yuan Wang, et al. "The C9orf72-interacting protein Smcr8 is a negative regulator of autoimmunity and lysosomal exocytosis." Genes & Development 32, no. 13-14 (2018): 929–43. http://dx.doi.org/10.1101/gad.313932.118.

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15

Xue, Bin, Ruiting Li, Haining Ma, Abdul Rahaman, and Vijay Kumar. "Comprehensive mapping of mutations in the C9ORF72 that affect folding and binding to SMCR8 protein." Process Biochemistry 121 (October 2022): 312–21. http://dx.doi.org/10.1016/j.procbio.2022.07.013.

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16

Shao, Qiang, Mei Yang, Chen Liang, et al. "C9orf72 and smcr8 mutant mice reveal MTORC1 activation due to impaired lysosomal degradation and exocytosis." Autophagy 16, no. 9 (2019): 1635–50. http://dx.doi.org/10.1080/15548627.2019.1703353.

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17

Amick, Joseph, Arun Kumar Tharkeshwar, Catherine Amaya,, and Shawn M. Ferguson. "WDR41 supports lysosomal response to changes in amino acid availability." Molecular Biology of the Cell 29, no. 18 (2018): 2213–27. http://dx.doi.org/10.1091/mbc.e17-12-0703.

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C9orf72 mutations are a major cause of amyotrophic lateral sclerosis and frontotemporal dementia. The C9orf72 protein undergoes regulated recruitment to lysosomes and has been broadly implicated in control of lysosome homeostasis. However, although evidence strongly supports an important function for C9orf72 at lysosomes, little is known about the lysosome recruitment mechanism. In this study, we identify an essential role for WDR41, a prominent C9orf72 interacting protein, in C9orf72 lysosome recruitment. Analysis of human WDR41 knockout cells revealed that WDR41 is required for localization
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18

Liang, Chen, Qiang Shao, Wei Zhang, et al. "Smcr8 deficiency disrupts axonal transport-dependent lysosomal function and promotes axonal swellings and gain of toxicity in C9ALS/FTD mouse models." Human Molecular Genetics 29, no. 6 (2020): 1056. http://dx.doi.org/10.1093/hmg/ddaa012.

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19

Leray, Xavier, Rossella Conti, Yan Li, et al. "Arginine-selective modulation of the lysosomal transporter PQLC2 through a gate-tuning mechanism." Proceedings of the National Academy of Sciences 118, no. 32 (2021): e2025315118. http://dx.doi.org/10.1073/pnas.2025315118.

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Lysosomes degrade excess or damaged cellular components and recycle their building blocks through membrane transporters. They also act as nutrient-sensing signaling hubs to coordinate cell responses. The membrane protein PQ-loop repeat-containing protein 2 (PQLC2; “picklock two”) is implicated in both functions, as it exports cationic amino acids from lysosomes and serves as a receptor and amino acid sensor to recruit the C9orf72/SMCR8/WDR41 complex to lysosomes upon nutrient starvation. Its transport activity is essential for drug treatment of the rare disease cystinosis. Here, we quantitativ
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20

Mulyana, Ade Mula, and Fahrunnisa Fahrunnisa. "Pola Komunikasi Penyuluh Pertanian Dalam Program Peningkatan Kapasitas Petani Jagung Di Kabupaten Sumbawa (Studi Kasus Kelompok Tani Desa Luk Kecamatan Rhee Kabupaten Sumbawa)." KAGANGA KOMUNIKA: Journal of Communication Science 3, no. 1 (2021): 10–19. http://dx.doi.org/10.36761/kagangakomunika.v3i1.1053.

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This is evident from the fact that Luk Village's petunia corn production has increased in the previous 5 years. In increasing the capacity of farmers this is caused by a communication process carried out by agricultural extension agents with farmer groups. So in this study the researcher intends to find out how the communication patterns of agricultural extension agents in the program to increase the capacity of maize farmers in Sumbawa Regency.This research uses a case study qualitative method. The theoretical analysis used is the SMCRE theory from David Kennet Berlo and the Communication Pat
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21

Newman, Jane D., Meghan M. Russell, Lixin Fan, Yun-Xing Wang, Giovanni Gonzalez-Gutierrez, and Julia C. van Kessel. "The DNA binding domain of the Vibrio vulnificus SmcR transcription factor is flexible and binds diverse DNA sequences." Nucleic Acids Research 49, no. 10 (2021): 5967–84. http://dx.doi.org/10.1093/nar/gkab387.

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Abstract Quorum sensing gene expression in vibrios is regulated by the LuxR/HapR family of transcriptional factors, which includes Vibrio vulnificus SmcR. The consensus binding site of Vibrio LuxR/HapR/SmcR proteins is palindromic but highly degenerate with sequence variations at each promoter. To examine the mechanism by which SmcR recognizes diverse DNA sites, we generated SmcR separation-of-function mutants that either repress or activate transcription but not both. SmcR N55I is restricted in recognition of single base-pair variations in DNA binding site sequences and thus is defective at t
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22

Ping, Zhongxin, Fang Xie, Xiaobo Gong, Liwu Liu, Jinsong Leng, and Yanju Liu. "Effects of Accelerated Aging on Thermal, Mechanical and Shape Memory Properties of Cyanate-Based Shape Memory Polymer: III Vacuum Thermal Cycling." Polymers 15, no. 8 (2023): 1893. http://dx.doi.org/10.3390/polym15081893.

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Shape memory polymers (SMPs) with intelligent deformability have shown great potential in the field of aerospace, and the research on their adaptability to space environments has far-reaching significance. Chemically cross-linked cyanate-based SMPs (SMCR) with excellent resistance to vacuum thermal cycling were obtained by adding polyethylene glycol (PEG) with linear polymer chains to the cyanate cross-linked network. The low reactivity of PEG overcame the shortcomings of high brittleness and poor deformability while endowing cyanate resin with excellent shape memory properties. The SMCR with
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23

Kim, Seung Min, Jin Hwan Park, Hyun Sung Lee, et al. "LuxR Homologue SmcR Is Essential for Vibrio vulnificus Pathogenesis and Biofilm Detachment, and Its Expression is Induced by Host Cells." Infection and Immunity 81, no. 10 (2013): 3721–30. http://dx.doi.org/10.1128/iai.00561-13.

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ABSTRACTQuorum sensing is a cell-to-cell communication system known to control many bacterial processes. In the present study, the functions of quorum sensing in the pathogenesis ofVibrio vulnificus, a food-borne pathogen, were assessed by evaluating the virulence of a mutant deficient in SmcR, a quorum-sensing regulator and homologue of LuxR. When biofilms were used as an inoculum, thesmcRmutant was impaired in virulence and colonization capacity in the infection of mice. The lack of SmcR also resulted in decreased histopathological damage in mouse jejunum tissue. These results indicated that
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24

Yonk, Ryan M., Josh T. Smith, and Arthur R. Wardle. "Exploring the Policy Implications of the Surface Mining Control and Reclamation Act." Resources 8, no. 1 (2019): 25. http://dx.doi.org/10.3390/resources8010025.

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This paper explores how policy structure, institutions, and political climate impact the ability of the Surface Mining Control and Reclamation Act (SMCRA) to ensure the reclamation of surface coal mines. We conduct a policy review that traces the impacts of the three parts of SMCRA; Reclamation Standards, Reclamation Bonding Requirements, and the Abandoned Mine Land fund. We examine the implications the act and its approach have for the mining industry and their ability to reclaim mining areas. We find that each of the three parts of SMCRA’s approach face substantial problems in their implemen
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25

Emison, R., and R. J. Shostak. "Pipelines and Subsidence: Overlooked in SMCRA." Journal American Society of Mining and Reclamation 1994, no. 4 (1994): 322–28. http://dx.doi.org/10.21000/jasmr94040322.

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26

Groninger, John W., Stephen D. Fillmore, and Ron A. Rathfon. "Stand Characteristics and Productivity Potential of Indiana Surface Mines Reclaimed Under SMCRA." Northern Journal of Applied Forestry 23, no. 2 (2006): 94–99. http://dx.doi.org/10.1093/njaf/23.2.94.

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Abstract The Surface Mining Control and Reclamation Act of 1977 (SMCRA) addresses a wide range of environmental concerns. However, its impacts on forest stand development and productive potential have only recently been investigated. We surveyed the vegetation and forest productivity on 22 surfacemine sites throughout the coal-bearing region of Indiana that were reclaimed to forest cover under the provisions of SMCRA 7–14 years prior to sampling. Black locust (Robinia pseudoacacia) and green ash (Fraxinus pennsylvanica) were the most widely occurring tree species.Tall fescue and goldenrod were
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27

Wu, Ming, Shelley Schwartz, Steven C. Cramer, Steven C. Cramer, and Michael Su. "Going Down the Rabbit Hole: Functional Recovery from Alice in Wonderland Syndrome during Rehabilitation Therapy. A Case Report." SM Case Reports 10, no. 3 (2024): 1–3. https://doi.org/10.36876/smcr.1102.

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Cognitive deficits can impact functional outcomes as well as the efficacy of rehabilitation therapy after stroke, but these must be understood in the context of the specific cognitive impairments. We describe here functional improvement during admission to an inpatient rehabilitation facility (IRF) in a patient with an uncommon form of cognitive abnormality, Alice in Wonderland Syndrome (AIWS), which is characterized by visual and other perceptual distortions. The course of this syndrome in the context of inpatient rehabilitation therapy has not been previously described. A 52-year-old male wi
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28

Merkin, Zina R., and Thomas J. Nieman. "REINTERPRETING SMCRA: "PERMITTING" PHASED POSTMINING LAND USE." Journal American Society of Mining and Reclamation 1996, no. 1 (1996): 766–80. http://dx.doi.org/10.21000/jasmr96010766.

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29

Nurwahidah Karim, Yusriani, and Fairus Prihatin Idris. "Hubungan Model Komunikasi SMCR Bidan di Desa dengan Perilaku Ibu Hamil dalam Mencegah Hipertens." Window of Public Health Journal 2, no. 4 (2021): 563–69. http://dx.doi.org/10.33096/woph.v2i4.220.

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Data provinsi Sulawesi Selatan tahun 2015 prevalensi hipertensi pada perempuan 47,73% lebih besar dibandingkan dengan laki-laki 38,51%. Data dari dinas kesehatan Kabupaten Luwu Utara pada tahun 2019 ditemukan 5656 ibu hamil dengan usia 15-39 tahun dan diperoleh angka ibu hamil beresiko terjadi hipertensi sebanyak 739 ibu hamil. Jenis penelitian yang digunakan adalah penelitian kuantitatif, menggunakan desain penelitian cross sectional yang bertujuan untuk mengetahui hubungan model komunikasi SMCR bidan desa dengan pengetahuan ibu hamil dalam mencegah hipertensi. Populasi dalam penelitian seban
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30

Pécsi, Balázs, and László Csaba Mangel. "The Real-Life Impact of Primary Tumor Resection of Synchronous Metastatic Colorectal Cancer—From a Clinical Oncologic Point of View." Cancers 16, no. 8 (2024): 1460. http://dx.doi.org/10.3390/cancers16081460.

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Aim: The complex medical care of synchronous metastatic colorectal (smCRC) patients requires prudent multidisciplinary planning and treatments due to various challenges caused by the primary tumor and its metastases. The role of primary tumor resection (PTR) is currently uncertain; strong arguments exist for and against it. We aimed to define its effect and find its best place in our therapeutic methodology. Method: We performed retrospective data analysis to investigate the clinical course of 449 smCRC patients, considering treatment modalities and the location of the primary tumor and compar
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31

Xiao, Yi, Xian Zhang, Ruiqi Wang, Chong Zheng, and Fuqiang Huang. "Synthesis, crystal structure, and magnetic properties of layered SmCrS2−xSexO solid solutions." Inorganic Chemistry Frontiers 7, no. 20 (2020): 3980–86. http://dx.doi.org/10.1039/d0qi00815j.

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32

Jeong, JiYeon, and Nohil Park. "Exploring Research Topics in Human - Artificial Intelligence Communication: Leveraging ChatGPT and the SMCRE Model." Journal of Digital Contents Society 24, no. 8 (2023): 1805–14. http://dx.doi.org/10.9728/dcs.2023.24.8.1805.

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33

Shao, Chung-Ping, and Lien-I. Hor. "Regulation of Metalloprotease Gene Expression in Vibrio vulnificus by a Vibrio harveyi LuxR Homologue." Journal of Bacteriology 183, no. 4 (2001): 1369–75. http://dx.doi.org/10.1128/jb.183.4.1369-1375.2001.

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ABSTRACT Expression of the Vibrio vulnificus metalloprotease gene, vvp, was turned up rapidly when bacterial growth reached the late log phase. A similar pattern of expression has been found in the metalloprotease gene of Vibrio cholerae, and this has been shown to be regulated by a Vibrio harveyiLuxR-like transcriptional activator. To find out whether a LuxR homologue exists in V. vulnificus, a gene library of this organism was screened by colony hybridization using a probe derived from a sequence that is conserved in various luxR-like genes of vibrios. A gene containing a 618-bp open reading
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34

Teh, Amy Huei Teen, Yi Wang, and Gary A. Dykes. "The influence of antibiotic resistance gene carriage on biofilm formation by two Escherichia coli strains associated with urinary tract infections." Canadian Journal of Microbiology 60, no. 2 (2014): 105–11. http://dx.doi.org/10.1139/cjm-2013-0633.

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Urinary tract infections (UTI) caused by uropathogenic Escherichia coli are one of the most common forms of human disease. In this study, the effect of the presence of newly acquired antibiotic resistance genes on biofilm formation of UTI-associated E. coli strains was examined. Two clinical UTI-associated E. coli strains (SMC18 and SMC20) carrying different combinations of virulence genes were transformed with pGEM-T, pGEM-T::KmΔAmp, or pGEM-T::Km to construct ampicillin-resistant (KmSAmpR), kanamycin-resistant (KmRAmpS), or ampicillin- and kanamycin-resistant (KmRAmpR) strains. Transformed a
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35

Tatsumi, Kazuyoshi, Yu Yamamoto, and Shunsuke Muto. "Site-by-Site Electronic Structure Analysis of Al-Containing Complex Compounds Using Channeling EELS and First Principles Calculations." Materials Science Forum 561-565 (October 2007): 2091–94. http://dx.doi.org/10.4028/www.scientific.net/msf.561-565.2091.

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Al K ELNES of oxide ceramics, which show reverse spinel and garnet structures containing two types of Al sites, are investigated site-selectively using TEM-EELS under electron channeling conditions. We applied a self-modeling curve resolution (SMCR) technique to separate a set of experimental spectra into individual spectra of individual atomic sites. The refined spectra after SMCR were in consistent with the theoretical spectra obtained by the first principles electronic structure calculations. The spectral difference of the six-coordinated aluminum between the two materials was discussed in
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36

Ma, Zhijie, Guanghui Liu, Weijun Gao, et al. "The tunable spin reorientation, temperature induced magnetization reversal, and spontaneous exchange bias effect of Sm0.7Y0.3Cr1−xGaxO3." RSC Advances 8, no. 58 (2018): 33487–95. http://dx.doi.org/10.1039/c8ra05720f.

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In this work, the tunable spin reorientation, temperature induced magnetization reversal, and spontaneous exchange bias effect were achieved in SmCrO<sub>3</sub> by codoping nonmagnetic ions at Sm- and Cr-sites.
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37

Gupta, Preeti, and Pankaj Poddar. "Study of magnetic and thermal properties of SmCrO3 polycrystallites." RSC Advances 6, no. 85 (2016): 82014–23. http://dx.doi.org/10.1039/c6ra17203b.

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SmCrO<sub>3</sub> polycrystallites exhibits inverse and normal magnetocaloric effect at and around spin reorientation transition (T<sub>SR</sub>) along with normal magnetocaloric effect at Néel transition (T<sub>N</sub>).
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38

Silva, Jhullyana Rocha, Larissa Mayara de Sousa Alencar, Lucas Costa Sá, and Marcos Vinícios Ferreira dos Santos. "As consequências da não utilização correta do protocolo de Manchester nos serviços de Urgência e Emergência." Research, Society and Development 11, no. 13 (2022): e324111335476. http://dx.doi.org/10.33448/rsd-v11i13.35476.

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Introdução: O Sistema Manchester de Classificação de Risco (SMCR) foi desenvolvido no Reino Unido por médicos e enfermeiros com a finalidade de priorizar o atendimento na emergência de acordo com critérios clínicos de maior risco com intuito de minimizar agravos à saúde do paciente. Objetivos: Identificar as principais dificuldades e desfechos clínicos durante o uso SMCR. Metodologia: Revisão integrativa da literatura através da pesquisa nas bases de dados PUBMED e SciELO, utilizando os descritores “triagem de Manchester” e “emergência” e suas variações em inglês. Foram incluídos os artigos pu
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39

Lee, Dong Hwan, Hye Sook Jeong, Hee Gon Jeong, Kyung Mo Kim, Heebal Kim, and Sang Ho Choi. "A Consensus Sequence for Binding of SmcR, aVibrio vulnificusLuxR Homologue, and Genome-wide Identification of the SmcR Regulon." Journal of Biological Chemistry 283, no. 35 (2008): 23610–18. http://dx.doi.org/10.1074/jbc.m801480200.

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40

Kadu, Brijesh S. "Suzuki–Miyaura cross coupling reaction: recent advancements in catalysis and organic synthesis." Catalysis Science & Technology 11, no. 4 (2021): 1186–221. http://dx.doi.org/10.1039/d0cy02059a.

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41

Tripathi, Malvika, R. J. Choudhary, and D. M. Phase. "Phase coexistence and the magnetic glass-like phase associated with the Morin type spin reorientation phase transition in SmCrO3." RSC Advances 6, no. 93 (2016): 90255–62. http://dx.doi.org/10.1039/c6ra21279d.

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SmCrO<sub>3</sub> undergoes a discontinuous Morin type spin reorientation process due to discrete flipping of Cr<sup>3+</sup> ions from the high temperature Γ<sub>4</sub> to low temperature Γ<sub>1</sub> configuration.
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42

Ashby, W. "Factors Limiting Tree Growth in Southern Illinois Under SMCRA." Journal American Society of Mining and Reclamation 1990, no. 1 (1990): 287–97. http://dx.doi.org/10.21000/jasmr90010287.

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43

Rodrigue, J. A., and J. A. Burger. "FOREST AND SITE PRODUCTIVITY ON PRE-SMCRA MINED LAND." Journal American Society of Mining and Reclamation 2001, no. 1 (2001): 121–33. http://dx.doi.org/10.21000/jasmr01010121.

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44

Pfannenstiel, Vern R., and Gary W. Wendt. "Twenty-Plus Years After SMCRA: Reflecting On The Results." Journal American Society of Mining and Reclamation 2002, no. 1 (2002): 992–1018. http://dx.doi.org/10.21000/jasmr02010992.

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45

Zipper, C. E., J. A. Burger, J. M. McGrath, and B. Amichev. "CARBON ACCUMULATION POTENTIALS OF POST-SMCRA COAL-MINED LANDS." Journal American Society of Mining and Reclamation 2007, no. 1 (2007): 962–80. http://dx.doi.org/10.21000/jasmr07010962.

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46

Болдырев, К. Н., Е. А. Добрецова, С. Ю. Гаврилкин, В. В. Мальцев та Н. И. Леонюк. "Магнитные фазовые переходы в новом мультиферроике SmCr3(BO3)4". Вестник НИЯУ МИФИ 3, № 4 (2014): 484–91. http://dx.doi.org/10.1134/s2304487x1404004x.

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47

Yin, L. H., Y. Liu, S. G. Tan, et al. "Multiple temperature-induced magnetization reversals in SmCr1−xFexO3 system." Materials Research Bulletin 48, no. 10 (2013): 4016–21. http://dx.doi.org/10.1016/j.materresbull.2013.06.016.

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48

Malinda, Ning Amirah. "Pola Dakwah Ustadzah Lilis Mulyani Terhadap Golongan Muallaf di Kota Kinabalu Sabah Malaysia." Anida (Aktualisasi Nuansa Ilmu Dakwah) 20, no. 2 (2020): 147–65. http://dx.doi.org/10.15575/anida.v20i2.8961.

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ABSTRACTThis study aims to determine methods, characteristics, and patterns of preaching to the converts. The object is Ustadzah Lilis Mulyani as a da'wah (Da'i) actor who conducts da'wah activities to converts in Teratak Fitrah Kota Kinabalu Sabah Malaysia. Researchers use a theory that is in accordance with the object of research, namely the SMCR theory found by David Berlo. This SMCR theory consists of: Source, Message, Channel, and Receiver. The source is what makes the message, while the message is the idea that is explained or the code in the form of symbols to be understood. The results
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49

Bulteau, Laurent, Guillaume Fertin, Géraldine Jean, and Christian Komusiewicz. "Sorting by Multi-Cut Rearrangements." Algorithms 14, no. 6 (2021): 169. http://dx.doi.org/10.3390/a14060169.

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A multi-cut rearrangement of a string S is a string S′ obtained from S by an operation called k-cut rearrangement, that consists of (1) cutting S at a given number k of places in S, making S the concatenated string X1·X2·X3·…·Xk·Xk+1, where X1 and Xk+1 are possibly empty, and (2) rearranging the Xis so as to obtain S′=Xπ(1)·Xπ(2)·Xπ(3)·…·Xπ(k+1), π being a permutation on 1,2,…,k+1 satisfying π(1)=1 and π(k+1)=k+1. Given two strings S and T built on the same multiset of characters from an alphabet Σ, the Sorting by Multi-Cut Rearrangements (SMCR) problem asks whether a given number ℓ of k-cut r
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Qian, Xiao-Long, Jian Kang, Bo Lu, Shi-Xun Cao, and Jin-Cang Zhang. "Kinetics of glass transition, negative magnetization and exchange bias effects in Sm1−xBixCrO3." RSC Advances 6, no. 13 (2016): 10677–82. http://dx.doi.org/10.1039/c5ra25006d.

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DC magnetization and magnetic relaxation studies of polycrystalline Sm<sub>1−x</sub>Bi<sub>x</sub>CrO<sub>3</sub> (x = 0, 0.1) demonstrated the kinetics of magnetic glass behaviour in SmCrO<sub>3</sub>: the frozen antiferromagnetic state was dominant to the glassy transition state.
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