Log in

Relevant bibliographies by topics / Spiroketal synthesis

Contents

Journal articles

Academic literature on the topic 'Spiroketal synthesis'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Spiroketal synthesis.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "Spiroketal synthesis"

1

Tlais, Sami F., and Gregory B. Dudley. "On the proposed structures and stereocontrolled synthesis of the cephalosporolides." Beilstein Journal of Organic Chemistry 8 (August 14, 2012): 1287–92. http://dx.doi.org/10.3762/bjoc.8.146.

Full text

Abstract:

The synthesis of four candidate stereoisomers of cephalosporolide H is described, made possible by a zinc-chelation strategy for controlling the stereochemistry of oxygenated 5,5-spiroketals. The same strategy likewise enables the first stereocontrolled synthesis of cephalosporolide E, which is typically isolated and prepared admixed with its spiroketal epimer, cephalosporolide F.

APA, Harvard, Vancouver, ISO, and other styles

2

Brimble, Margaret A., and Seng H. Chan. "Synthesis of 7-Methoxy-3′,4′,5′,6′-tetrahydrospiro-[isobenzofuran-1(3H),2′-pyran]-3-one and 5,7-Dimethoxy-3′,4′,5′,6′-tetrahydrospiro[isobenzofuran-1(3H),2′-pyran]-3-one." Australian Journal of Chemistry 51, no. 3 (1998): 235. http://dx.doi.org/10.1071/c97193.

Full text

Abstract:

The synthesis of novel aryl spiroketals, which contain a similar substitution pattern to that present in the antifungal agents the papulacandins, is described. Thus, spiroketal (7) was obtained from acid-catalysed cyclization of the keto alcohol (13), and spiroketal (8) was obtained from acid-catalysed cyclization of keto alcohols (12) and (19). Keto alcohols (12), (13) and (19) in turn were prepared by ortho-directed lithiation of amides (10), (11) and oxazoline (17) respectively, followed by reaction with δ-valerolactone. Substitution of the aromatic ring occurred at the sterically hindered

APA, Harvard, Vancouver, ISO, and other styles

3

Messerle, Barbara A., and Khuong Q. Vuong. "Synthesis of spiroketals by iridium-catalyzed double hydroalkoxylation." Pure and Applied Chemistry 78, no. 2 (2006): 385–90. http://dx.doi.org/10.1351/pac200678020385.

Full text

Abstract:

A highly efficient approach to the synthesis of spiroketals involves the double cyclization of alkynyl diols using transition-metal catalysts. The iridium complex [Ir(PyP)(CO)2]BPh4 where PyP = 1-[(2-diphenylphosphino)ethyl]pyrazole is an effective catalyst for promoting the formation of spiroketals via this double hydroalkoxylation reaction. The complex promotes the formation of a series of spiroketal products from alkynyl diol starting materials such as 3-ethynylpentane-1,5-diol and 2-(4-hydroxybut-1-ynyl)benzyl alcohol. Stereoselective cyclization occurs for 3-ethynylpentane-1,5-diol, 3-eth

APA, Harvard, Vancouver, ISO, and other styles

4

Tlais, Sami F., and Gregory B. Dudley. "A gold-catalyzed alkyne-diol cycloisomerization for the synthesis of oxygenated 5,5-spiroketals." Beilstein Journal of Organic Chemistry 7 (May 4, 2011): 570–77. http://dx.doi.org/10.3762/bjoc.7.66.

Full text

Abstract:

A highly efficient synthesis of oxygenated 5,5-spiroketals was performed towards the synthesis of the cephalosporolides. Gold(I) chloride in methanol induced the cycloisomerization of a protected alkyne triol with concomitant deprotection to give a strategically hydroxylated 5,5-spiroketal, despite the potential for regiochemical complications and elimination to furan. Other late transition metal Lewis acids were less effective. The use of methanol as solvent helped suppress the formation of the undesired furan by-product. This study provides yet another example of the advantages of gold catal

APA, Harvard, Vancouver, ISO, and other styles

5

Čikoš, Ana, Irena Ćaleta, Dinko Žiher, et al. "Structure and conformational analysis of spiroketals from 6-O-methyl-9(E)-hydroxyiminoerythronolide A." Beilstein Journal of Organic Chemistry 11 (August 19, 2015): 1447–57. http://dx.doi.org/10.3762/bjoc.11.157.

Full text

Abstract:

Three novel spiroketals were prepared by a one-pot transformation of 6-O-methyl-9(E)-hydroxyiminoerythronolide A. We present the formation of a [4.5]spiroketal moiety within the macrolide lactone ring, but also the unexpected formation of a 10-C=11-C double bond and spontaneous change of stereochemistry at position 8-C. As a result, a thermodynamically stable structure was obtained. The structures of two new diastereomeric, unsaturated spiroketals, their configurations and conformations, were determined by means of NMR spectroscopy and molecular modelling. The reaction kinetics and mechanistic

APA, Harvard, Vancouver, ISO, and other styles

6

McLeod, Michael C., Margaret A. Brimble, Dominea C. K. Rathwell, Zoe E. Wilson, and Tsz-Ying Yuen. "Synthetic approaches to [5,6]-benzannulated spiroketal natural products." Pure and Applied Chemistry 84, no. 6 (2011): 1379–90. http://dx.doi.org/10.1351/pac-con-11-08-06.

Full text

Abstract:

Studies toward the synthesis of three biologically active [5,6]-benzannulated spiroketal natural products are described. The first total synthesis of paecilospirone is reported, employing a late-stage, pH-neutral spiroketalization. A formal synthesis of γ-rubromycin is described, where the spiroketal moiety is formed by delicate manipulation of the electronic properties of the spirocyclization precursor. Finally, model work toward the total synthesis of berkelic acid is summarized, introducing a novel Horner–Wadsworth–Emmons/oxa-Michael (HWE/oxa-M) cascade to access the spiroketal precursor.

APA, Harvard, Vancouver, ISO, and other styles

7

Quayle, Peter, Jeremy C. Conway, Andrew C. Regan, and Christopher J. Urch. "A Palladium Mediated Spiroketal Synthesis." HETEROCYCLES 67, no. 1 (2006): 85. http://dx.doi.org/10.3987/com-05-s(t)20.

Full text

APA, Harvard, Vancouver, ISO, and other styles

8

Elsley, David A., Donald MacLeod, John A. Miller, Peter Quayle, and Gareth M. Davies. "A palladium mediated spiroketal synthesis." Tetrahedron Letters 33, no. 3 (1992): 409–12. http://dx.doi.org/10.1016/s0040-4039(00)74144-x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

9

Ramakrishna, Bandi, and Perali Ramu Sridhar. "Stereoselective synthesis of 1,6-dioxaspirolactones from spiro-cyclopropanecarboxylated sugars: total synthesis of dihydro-pyrenolide D." RSC Advances 5, no. 11 (2015): 8142–45. http://dx.doi.org/10.1039/c4ra16753h.

Full text

Abstract:

A one-pot protocol for the stereoselective construction of γ-spiroketal γ-lactone frameworks from sugar derived spiro-cyclopropanecarboxylic acids involving a ring enlargement and cyclization reaction is revealed.

APA, Harvard, Vancouver, ISO, and other styles

10

Conway, Jeremy C., Peter Quayle, Andrew C. Regan, and Christopher J. Urch. "Palladium mediated spiroketal synthesis: application to pheromone synthesis." Tetrahedron 61, no. 50 (2005): 11910–23. http://dx.doi.org/10.1016/j.tet.2005.09.055.

Full text

APA, Harvard, Vancouver, ISO, and other styles

More sources

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!