Academic literature on the topic 'Styrylchromones'

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Journal articles on the topic "Styrylchromones"

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C., Srinivas Rao, Jyotsna C., and S. Sait Shakil. "Palladium-mediated cyclization of 8-allyl-7 -hydroxy-2-styrylchrmnones towards the synthesis of 7 ,8-furano-2-styrylchromones." Journal of Indian Chemical Society Vol. 89, Sep 2012 (2012): 1283–87. https://doi.org/10.5281/zenodo.5769715.

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JNTUH, Dr. Reddy Laboratories, Hyderabad, India E-mail : chemistrycsr@gmail.com Manuscript received 17 February 2011, revised 13 December 2011, accepted 21 December 2011 A rapid, efficient and practical synthesis of 7,8-furano-2-styrylchromones by oxidation of 8-allyl-7-hydroxy-2-styrylchromones with dichlorobis(benzonitrile)palladium has been developed. This procedure is general and the products thus obtained have been characterized from their spectral data. DDQ oxidation of the same substrates, however, gave 7 ,8-pyrano-2-styrylchromone derivatives.
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Rocha, Sónia, Natália Aniceto, Rita C. Guedes, et al. "An In Silico and an In Vitro Inhibition Analysis of Glycogen Phosphorylase by Flavonoids, Styrylchromones, and Pyrazoles." Nutrients 14, no. 2 (2022): 306. http://dx.doi.org/10.3390/nu14020306.

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Glycogen phosphorylase (GP) is a key enzyme in the glycogenolysis pathway. GP inhibitors are currently under investigation as a new liver-targeted approach to managing type 2 diabetes mellitus (DM). The aim of the present study was to evaluate the inhibitory activity of a panel of 52 structurally related chromone derivatives; namely, flavonoids, 2-styrylchromones, 2-styrylchromone-related derivatives [2-(4-arylbuta-1,3-dien-1-yl)chromones], and 4- and 5-styrylpyrazoles against GP, using in silico and in vitro microanalysis screening systems. Several of the tested compounds showed a potent inhi
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Momin, Mehbub, Deresh Ramjugernath, Hafizah Chenia, and Neil A. Koorbanally. "Synthesis and Evaluation of Novel Fluorinated 2-Styrylchromones as Antibacterial Agents." Journal of Chemistry 2013 (2013): 1–13. http://dx.doi.org/10.1155/2013/436758.

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A range of fluorinated 2-styrylchromones (5a–g) of which six were new (5a–f) were prepared in three steps using the Baker-Venkataraman rearrangement along with two methoxylated derivatives (5h-i) and a methylenedioxy derivative (5j) and screened for their antibacterial activity using Gram-positive bacteria (Staphylococcus aureus, sciuri, andxylosusas well asBacillus subtilis) and Gram-negative bacteria (Escherichia coli, Pseudomonas aeruginosa, andKlebsiella pneumonia). The compounds were most effective againstB. subtilisfollowed byS. aureusand a single strain ofE. coli(ATCC 25922). Difluorina
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Simon, Lalitha. "IN-VITRO CYTOTOXICITY AND ANTIOXIDANT EVALUATION OF 7-AMINO-2-STYRYLCHROMONE DERIVATIVES." Asian Journal of Pharmaceutical and Clinical Research 10, no. 11 (2017): 152. http://dx.doi.org/10.22159/ajpcr.2017.v10i11.20587.

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Objective: The objective of this study was to synthesize 7-amino-2-styrylchromone derivatives and evaluate their in vitro cytotoxic and antioxidant potential.Methods: 7-amino-2-styrylchromones were synthesized from 7-amino-2-methylchromone by condensing it with various substituted aromatic aldehydes. The cytotoxicity of the synthesized molecules was assessed against two cell lines, MCF-7 and HCT-116 by 3-(4,5-dimethyl thiazol-2-yl)-2,5- diphenyl tetrazolium bromide assay. Cell cycle analysis of the most potent molecule ASC-7 was carried out. The antioxidant studies were conducted by 2,2-diphen
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Talhi, Oualid, Artur Silva, Abdelghani Bouchama, et al. "Diastereoselective One-Pot Tandem Synthesis of Chromenopyridodiazepinones through 1,4- and 1,6-Aza-Conjugate Additions/Heterocyclizations." Synlett 29, no. 07 (2018): 885–89. http://dx.doi.org/10.1055/s-0037-1609201.

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We report an efficient one-pot synthesis of a novel series of chromenopyridodiazepinone polyheterocycles by a catalyst-free nucleo­philic addition of ethane-1,2-diamine to (E,E)-3-[3-(2-hydroxyphenyl)-3-oxoprop-1-en-1-yl]-2-styrylchromones at room temperature under mild conditions. The reaction proceeds by a tandem process involving 1,4- and 1,6-aza-conjugate additions of one amino group of ethane-1,2-diamine to the α,β-unsaturated (3-oxoprop-1-en-1-yl) and the α,β,γ,δ-diunsaturated (2-styrylchromone) carbonyl system of the precursor, followed by imine condensation of the remaining amino group
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Desideri, Nicoletta, Paola Mastromarino, and Cinzia Conti. "Synthesis and Evaluation of Antirhinovirus Activity of 3-Hydroxy and 3-Methoxy 2-Styrylchromones." Antiviral Chemistry and Chemotherapy 14, no. 4 (2003): 195–203. http://dx.doi.org/10.1177/095632020301400404.

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Recently, we identified 2-styrylchromones as a new class of antirhinovirus flavonoids with moderate activity against both rhinovirus groups A and B. In order to improve the antiviral effect of the first series of tested 2-styrylchromones, a hydroxy or methoxy group was introduced in position 3 of the chromone ring. Cytotoxicity and antiviral activity of the new synthesized compounds were evaluated in HeLa cell cultures infected with rhinoviruses 1B and 14, selected as representative serotypes for viral groups B and A of human rhinoviruses (HRVs), respectively. These antiviral results compared
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Lucas, Mariana, Marisa Freitas, Artur M. S. Silva, Eduarda Fernandes, and Daniela Ribeiro. "Styrylchromones: Biological Activities and Structure-Activity Relationship." Oxidative Medicine and Cellular Longevity 2021 (December 22, 2021): 1–47. http://dx.doi.org/10.1155/2021/2804521.

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Styrylchromones (SC) are a group of oxygen-containing heterocyclic compounds, which are characterized by the attachment of a styryl group to the chromone core. SC can be found in nature or can be chemically synthesized in the laboratory. As their presence in nature is scarce, the synthetic origin is the most common. Two types of SC are known: 2-styrylchromones and 3-styrylchromones. However, 2-styrylchromones are the most common, being more commonly found in nature and which chemical synthesis is more commonly described. A wide variety of SC has been described in the literature, with different
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Sankar, P. Dey, Chattopadhyay Falguni, and K. Mallik Asok. "Hypervalent iodine oxidation of flavonols and 3-hydroxy-2-styrylchromones in different alcohols." Journal of Indian Chemical Society Vol. 93, Nov 2016 (2016): 1321–24. https://doi.org/10.5281/zenodo.5639274.

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Department of Chemistry, Srikrishna College, Bagula, Nadia-741 502, West Bengal, India <em>E-mail</em> : deysp2002@yahoo.co.in Department of Chemistry, Jadavpur University, Kolkata-700 032, India <em>Manuscript received 18 May 2016, revised 08 September 2016, accepted 19 September 2016</em> Flavonols and 3-hydroxy-2-styrylchromones react with diacetoxyiodobenzene (DAIB) in different alcohols to yield addition compound. Alcohols used as solvent in the oxidation process add to the C-2 carbon of both the flavonols and 3-hydroxy-2-styrylchromones.
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Silva, Artur M. S., Diana C. G. A. Pinto, José A. S. Cavaleiro, Albert Levai, and Tamás Patonay. "Synthesis and reactivity of styrylchromones." Arkivoc 2004, no. 7 (2004): 106–23. http://dx.doi.org/10.3998/ark.5550190.0005.709.

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Gomes, Ana, Marisa Freitas, Eduarda Fernandes, and Jose L.F.C. Lima. "Biological Activities of 2-Styrylchromones." Mini-Reviews in Medicinal Chemistry 10, no. 1 (2010): 1–7. http://dx.doi.org/10.2174/138955710791112550.

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Dissertations / Theses on the topic "Styrylchromones"

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Gomes, Ana Maria de Carvalhais Mendes. "Evaluation of the antioxidant and anti-inflammatory activities of synthetic 2-styrylchromones." Doctoral thesis, Faculdade de Farmácia da Universidade do Porto, 2008. http://hdl.handle.net/10216/20815.

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Pereira, Joana Duarte da Rocha. "Searching for antivirals agaist norovirus: 2-Styrylchromones as potential anti-norovirus agents." Master's thesis, Faculdade de Farmácia da Universidade do Porto, 2008. http://hdl.handle.net/10216/20864.

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Pereira, Joana Duarte da Rocha. "Searching for antivirals agaist norovirus: 2-Styrylchromones as potential anti-norovirus agents." Dissertação, Faculdade de Farmácia da Universidade do Porto, 2008. http://hdl.handle.net/10216/20864.

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Gomes, Ana Maria de Carvalhais Mendes. "Evaluation of the antioxidant and anti-inflammatory activities of synthetic 2-styrylchromones." Tese, Faculdade de Farmácia da Universidade do Porto, 2008. http://hdl.handle.net/10216/20815.

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Santos, Clementina M. M. "Transformações de cetonas α,β- e α,β,γ,δ-insaturadas. Novas rotas de síntese de 2,3-diarilxantonas". Doctoral thesis, Universidade de Aveiro, 2007. http://hdl.handle.net/10198/1050.

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Esta dissertação é constituída por duas partes: na primeira parte reportam-se estudos de epoxidação em cetonas α,β- e α,β,γ,δ-insaturadas, catalisados por um complexo de salen Mn(III), conhecido como catalisador de Jacobsen; na segunda parte desenvolvem-se novas rotas de síntese de 2,3-diarilxantonas em que se recorre à reacção de Heck de cromonas bromadas com estirenos. Os estudos de epoxidação apresentados na primeira parte desta dissertação foram efectuados em três sistemas carbonílicos α,β- e α,β,γ,δ-insaturados: (E)-calconas, (E,E)-cinamilidenoacetofenonas e (E)-2-estirilcromonas e utili
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Lin, Chen, and 林辰. "Structure-Activity Relationship Study of 2-Styrylchromones Targeting Carcinoma Cell Lines." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/67045535147119706694.

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碩士<br>淡江大學<br>化學學系碩士班<br>98<br>Previously, we have synthesized a series of 2-styrylchromones that exhibited anticancer effect against carcinoma cells (EJMC, 2009, 44(6), 2552-2562). In this study, we initially focused on the structural modific- ations on B-ring while A-ring was free of substitution. The synthetic route of 2-styrylchromones was carried out in three steps that afforded 52a-q based on the abovementioned work. With seventeen analogs in hand, we examined their growth inhibition on a panel of carcinoma cell lines. Interestingly, 52d, 52l and 52q bearing 4’-methoxy, 3’,4’-difluoro
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Correia, Catarina Marçal. "(E)-2-styrylchromones: synthesis and evaluation of the inhibitory effects on the oxidative burst produced by human monocytes." Master's thesis, 2021. http://hdl.handle.net/10773/33584.

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Several studies have attributed the onset and progression of several diseases, including degenerative and cardiovascular diseases, cell aging and cancer, to the production of free radicals and inflammatory processes. Consequently, a large number of investigations have been carried out in order to find new, safer and potent antioxidant and anti-inflammatory drugs, and to elucidate their corresponding mechanisms of action. The evaluation of antioxidant vs antiradicalar and anti-inflammatory activity of phenolic compounds, either of natural or synthetic origin, is nowadays an important are
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Tomé, Sara Mirassol. "Synthesis of flavonoid-type compounds and sugar-substituted phenolics of pharmacological importance." Doctoral thesis, 2021. http://hdl.handle.net/10773/31390.

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Flavonoids are a large class of secondary metabolites widespread in the Plant Kingdom. These natural organic compounds possess a prominent interest as therapeutic agents. Among the vast range of biological properties of both natural and synthetic derivatives are their antioxidant and anti-inflammatory activities. Among the naturally occurring oxygen containing heterocyclic compounds, flavones (2-arylchromones) assume pronounced importance due to both their spread and diverse abundance as well as their well-known wide range of pharmacological properties. Halogenated derivatives of
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Chang, Chun-Yi, and 張峻誼. "Synthesis of 2-Styrylchromone and 8-Hydroxyquinoline Derivatives as Anticancer Agents." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/38371500242574807026.

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碩士<br>淡江大學<br>化學學系碩士班<br>98<br>The first part : A series of 2-styrylchromone analogs were synthesized and examined for their antiproliferative effects on a panel of carcinoma cells. Among the tested agents, only 34 exhibited a moderate activity with an IC50 value of 28.9 μM against PC-3 cells which indicates the selectivity of PC-3 cells in response to 2-styrylchromones. In addition, 38 demonstrated the most antiproliferative effect with an IC50 value of 4.9 μM against HeLa cells. Together, these results suggest a potential structural optimization and pharmacological study of 2-styrylchromones
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Conference papers on the topic "Styrylchromones"

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Lucas, Mariana, Marisa Freitas, Artur M. S. Silva, Eduarda Fernandes, and Daniela Ribeiro. "2-Styrylchromones Modulate Prostaglandins Production through the Inhibition of COX-2." In ECMC 2022. MDPI, 2022. http://dx.doi.org/10.3390/ecmc2022-13232.

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Rufino, Ana Teresa, Mariana Lucas, Artur M. S. Silva, Eduarda Fernandes та Daniela Ribeiro. "2-Styrylchromones Inhibit IL-1β-Induced Inflammatory Mediators’ Production in Human Fibroblast-like Synoviocytes". У ECMC 2022. MDPI, 2022. http://dx.doi.org/10.3390/ecmc2022-13183.

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Lucas, Mariana, Marisa Freitas, Artur M. S. Silva, Eduarda Fernandes, and Daniela Ribeiro. "Modulation of Human Neutrophils’ Oxidative Burst by Hydroxylated 2-Styrylchromones: The Relevance of the Catechol Group." In ECB 2021. MDPI, 2021. http://dx.doi.org/10.3390/ecb2021-10283.

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Lucas, Mariana, Daniela Ribeiro, Marisa Freitas, Joana Sousa, Artur Silva, and Eduarda Fernandes. "The impact of B-ring substituents on the styrylchromones' ability to modulate the levels of reactive prooxidant species." In 7th International Electronic Conference on Medicinal Chemistry. MDPI, 2021. http://dx.doi.org/10.3390/ecmc2021-11521.

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Monteiro, Ricardo, Daniela Ribeiro, Mariana Lucas, et al. "Chalcones &lt;em&gt;versus&lt;/em&gt; 2-styrylchromones: Which are the best oxygen and nitrogen reactive species scavengers?" In 7th International Electronic Conference on Medicinal Chemistry. MDPI, 2021. http://dx.doi.org/10.3390/ecmc2021-11494.

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