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Journal articles on the topic 'Synthesis of 2-amino-4'

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Published: 5 June 2025

Last updated: 1 August 2025

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1

KHADIGA, M. GHONBIM, EL-TELBANY FARAG, and YOUSSEF KHAIRIA. "Synthesis and Evaluation of some 2-, 4- and 2,4- Di-substituted.-6-methylpyrimidine Derivatives for Antimicrobial Activity." Journal of Indian Chemical Society Vol. 63, Oct 1986 (1986): 914–17. https://doi.org/10.5281/zenodo.6302313.

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Organic Chemistry Department, Faculty of Pharmacy, Cairo University, Cairo, Egypt <em>Manuscript received</em> <em>23 September 1986, accepted 2 August 1986</em> The reaction of 2-amino-4-cbloro-, 4-amino-2-chloro- and 2,4-dichloro-6-methylpyrimidines with primary aromatic amines under acidic conditions is presented. 2-, and 4-<sup>\(\omega\)</sup>-substituted-thioureido-6-methylpyrimidines were synthesised via the reaction of 2-amino-and 4-amino-6-metbylpyrimidine derivatives with arylisocyanates. Six compounds were evaluated for their antimicrobial activity and most of them sh

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2

Protiva, Jiří, Václav Křeček, Bohumil Máca, Jiří Urban, Miloš Buděšínský, and Miloš Procházka. "Synthesis of 4-(N-acetyl-L-tyrosyl)amino-2-iodobenzoic acid." Collection of Czechoslovak Chemical Communications 54, no. 4 (1989): 1012–18. http://dx.doi.org/10.1135/cccc19891012.

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The title compound was prepared by a three-step synthesis from diacetyltyrosine (XV) and 4-amino-2-iodobenzoic acid (I). Syntheses of acid I and 4-amino-3-iodobenzoic acid (II) have been revised and modified. 1H and 13C NMR spectra of the synthesized compounds are discussed.

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3

Metwally, M. A., Abdelbasset A. Farahat, and Bakr F. Abdel-Wahab. "2-Amino-4-thiazolidinones: synthesis and reactions." Journal of Sulfur Chemistry 31, no. 4 (2010): 315–49. http://dx.doi.org/10.1080/17415993.2010.482155.

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4

CHEN, Qifan*, Huidong ZHANG, and Shengchen GONG. "Synthesis of 4-Substituted-2-amino-pyrimidines." Chinese Journal of Applied Chemistry 28, no. 04 (2011): 382–86. http://dx.doi.org/10.3724/sp.j.1095.2011.00372.

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5

Valarmathy, Govindaraj, Ramanathan Subbalakshmi, Rajendran Nithya, Ragu Nandhini, Balachandaran Sabarika, and Elanchleiyan Aarthy. "Synthesis, Spectral Characterisation and Cytotoxic Evaluation of Substituted Sulfonamide Schiff Bases." Indian Journal of Science and Technology 14, no. 34 (2021): 2731–41. https://doi.org/10.17485/IJST/v14i34.888.

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Abstract <strong>Objectives:</strong> To synthesize Schiff bases i.e 4-((2-hydroxybenzylidene)-amino–N-(5-methyl-1,2-oxozol-3- yl)benzene sulphonamide (L1), 4-((2-hydroxy benzylidene)-amino-N-(thiazol-yl)benzene sulphonamide (L2), 4-((2-hydroxybenzylidene)amino-N-(pyridin-2-yl)benzene sulphonamide by theaction of 2-hydroxybenzaldehyde with sulfathiazole/ sulfamethoxazole/ sulfapyridine in ethanolic media. <strong>Methods:</strong> The Schiff bases obtained were characterized by analytical data, IR, UV, 1H- NMR, 13C-NMR, Mass spectrum and monitored for cytotoxic activity ag

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6

S., P. HIREMATH, K. S. SWAMY H., H. M. MRUTHYUNJAYASWAMY B., M. PATIL S., M. K. SWAMY K., and M. SHANT AKUMAR S. "Studies on the Synthesis of Biheterocycles and their Biological Activities." Journal of Indian Chemical Society Vol. 72, Jun 1995 (1995): 391–93. https://doi.org/10.5281/zenodo.5904967.

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Department of Chemistry, Gulbarga University, Gulbarga-585 106 Department of Pharmaceutical Chemistry, V. L. College of Pharmacy, Raichur-584 101 <em>Manuscript received 28 June 1993, revised 26 November 1993, accepted 11 January 1994</em> 4-Amino-5-(2' -phenylindol-3' -yl)amino-3-phenoxymethyl-1 ,2,4-triazoles (3a-d), 5-(2' -phenylindol-3' -yl)amino-2-phenoxymethyl-1,3,4-qxadiazoles (4a-d), 4-(2' -phenylindol-3' -yl)-5-phenoxymethyl-1,2,4-triazole-3-thiones (5a-d) and 2-(2'- phenylindol-3'-yl)imino-3-phenoxyacetamido-5<em>H</em>-1,3-thiazolidin-4-ones (6a&middo

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7

S P, Jisha. "Synthesis and Bioactivity OF 2-Amino-5-(3-Arylsydnon-4-OYL) Thiazoles." International Journal of Science and Research (IJSR) 6, no. 12 (2017): 1993–95. http://dx.doi.org/10.21275/es17121110313.

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8

B., R. MODI, R. DESAI N., B. D. MISTRY (MS.), and R. DESAI K. "Synthesis of Azo Disperse Dyes from 2-(1',4' -Bis-styryl- 4" -chloro )-6-amino-4-oxoquinazoline." Journal of Indian Chemical Society Vol. 71, Nov 1994 (1994): 701–4. https://doi.org/10.5281/zenodo.5897681.

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Department of Chemistry, South Gujarat University, Surat-395 007 <em>Manuscript received 21 January 1993, revised 17 August 1993, accepted 29 September 1993</em> Synthesis of Azo Disperse Dyes from 2-(1',4' -Bis-styryl- 4" -chloro )-6-amino-4-oxoquinazoline

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9

Fadnavis, Nitin W., Su-Hyun Seo, Joo-Hyun Seo, and Byung-Gee Kim. "Asymmetric synthesis of nonproteinogenic amino acids with l-amino acid transaminase: synthesis of (2S)-2-amino-4-oxo-4-phenylbutyric and (3E,2S)-2-amino-4-phenylbutenoic acids." Tetrahedron: Asymmetry 17, no. 15 (2006): 2199–202. http://dx.doi.org/10.1016/j.tetasy.2006.07.034.

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10

V., N. PATOLIA, K. PATEL P., and J. BAXI A. "Studies on 4-Thiazolidinones. Part-IX. Synthesis and Antimicrobial Activity of 2-(2'-Aryl-4-thiazolidinon-3'-yl)- 4-(2" -methyl-4" -hydroxy-5"-isopropylphenyl)thiazoles." Journal of Indian Chemical Society Vol. 71, Nov 1994 (1994): 683–85. https://doi.org/10.5281/zenodo.5897621.

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Department of Chemistry, Saurashtra University, Rajkot-360 005 <em>Manuscript received 25 August 1992, revised 7 September 1993, accepted 17 September 1993</em> Several new 4-thiazolidinones have been prepared bearing 2-amino-4-(2'-methyl-4'-hydroxy-5'-isopropylphenyl)thiazole moiety. Their structures have been supported by ir and mass spectral studies. The products have been screened for their antimicrobial activity.

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11

Fernández, M. Carmen, Marı́a Ruiz, Vicente Ojea, and José M. Quintela. "Diastereoselective synthesis of 4-alkylidene-2-amino-4-phosphonobutanoic acids." Tetrahedron Letters 43, no. 34 (2002): 5909–12. http://dx.doi.org/10.1016/s0040-4039(02)01275-3.

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12

Fernández, M. Carmen, José M. Quintela, Marı́a Ruiz, and Vicente Ojea. "Diastereoselective synthesis of 4-substituted 2-amino-4-phosphonobutanoic acids." Tetrahedron: Asymmetry 13, no. 3 (2002): 233–37. http://dx.doi.org/10.1016/s0957-4166(02)00082-4.

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13

Mavrov, M. V., L. D. Konyushkin, N. I. Simirskaya, and S. G. Zlotin. "Synthesis of 4-amino-substituted but-2-en-4-olides." Russian Chemical Bulletin 54, no. 12 (2005): 2857–66. http://dx.doi.org/10.1007/s11172-006-0201-7.

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14

Abbenante, Giovanni, Robert Hughes, and Rolf H. Prager. "Potential GABA B Receptor Antagonists. IX The Synthesis of 3-Amino-3-(4-chlorophenyl)propanoic Acid, 2-Amino-2-(4-chlorophenyl)ethylphosphonic Acid and 2-Amino-2-(4-chlorophenyl)ethanesulfonic Acid." Australian Journal of Chemistry 50, no. 6 (1997): 523. http://dx.doi.org/10.1071/c96216.

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This paper describes the synthesis of 3-amino-3-(4-chlorophenyl)propanoic acid and the corresponding phosphonic and sulfonic acids, lower homologues of baclofen, phaclofen and saclofen respectively. The chlorinated acids were all weak specific antagonists of GABA at the GABAB receptor, with the sulfonic acid (pA2 4·0) being stronger than the phosphonic acid (pA2 3·8) and carboxylic acid (pA2 3·5).

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15

M., A. DAVE, and B. MAHABAL N. "Synthesis of 3-Amino-1 ,4-diarylazetidin-2-ones. Part - I." Journal of Indian Chemical Society Vol. 70, Feb 1993 (1993): 172–73. https://doi.org/10.5281/zenodo.5917662.

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Department of Chemistry, K. J. Somaiya College of Science, Vidyavihar, Bombay-400 077 <em>Manuscript received 6 July 1990, revised 25 September 1992, accepted 12 November 1992</em> Synthesis of 3-Amino-1 ,4-diarylazetidin-2 -ones. Part - I

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16

Bursavich, Matthew G., Sabrina Lombardi, and Adam M. Gilbert. "Expedient Parallel Synthesis of 2-Amino-4-heteroarylpyrimidines." Organic Letters 7, no. 19 (2005): 4113–16. http://dx.doi.org/10.1021/ol051339z.

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17

Humphries, Paul S., Quyen-Quyen T. Do, and David M. Wilhite. "Chemically enabled synthesis of 2-amino-4-heteroarylpyrimidines." Tetrahedron Letters 50, no. 21 (2009): 2552–54. http://dx.doi.org/10.1016/j.tetlet.2009.03.073.

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18

Zieliński, Wojciech, and Agnieszka Kudelko. "Synthesis and Basicity of 4-Amino-2-phenylquinazolines." Monatshefte fuer Chemie/Chemical Monthly 131, no. 8 (2000): 895–99. http://dx.doi.org/10.1007/s007060070067.

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19

Dorokhov, V. A., A. V. Komkov, A. M. Sakharo, and V. S. Bogdanov. "Synthesis of 3-acetyl-2-amino-4-pyridone." Russian Chemical Bulletin 45, no. 1 (1996): 168–70. http://dx.doi.org/10.1007/bf01433755.

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20

Bergman, Jan, Anna Brynolf, and Eino Vuorinen. "A new synthesis of 4-amino-2-quinolinones." Tetrahedron 42, no. 13 (1986): 3689–96. http://dx.doi.org/10.1016/s0040-4020(01)87337-3.

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21

Obushak, N. D., V. S. Matiichuk, N. I. Ganushchak, and R. L. Martyak. "Synthesis of 4-amino-5-arylmethyl-2-bromothiazoles." Chemistry of Heterocyclic Compounds 33, no. 8 (1997): 1000. http://dx.doi.org/10.1007/bf02253182.

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22

Sheremetev, Aleksei B., and Igor V. Ovchinnikov. "Synthesis of 3-amino-4-(thienyl-2)furazan." Heteroatom Chemistry 8, no. 1 (1997): 7–12. http://dx.doi.org/10.1002/(sici)1098-1071(1997)8:1<7::aid-hc2>3.0.co;2-d.

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23

Strizhenko, Kirill V., Leonid S. Vasil’ev, Kyrill Yu Suponitsky, and Aleksei B. Sheremetev. "3-Amino-4-(1-amino-2-cyanovinyl)furazans: synthesis and cyclization." Chemistry of Heterocyclic Compounds 56, no. 8 (2020): 1103–7. http://dx.doi.org/10.1007/s10593-020-02781-7.

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24

SHIRISH, A. PATIL, and BAGAVANT G. "Synthesis and Antiinflammatory Activity of Substituted 2-Amino-4-carboxy-5-thiazoleacetic Acids." Journal of Indian Chemical Society Vol. 71, April 1994 (1994): 205–7. https://doi.org/10.5281/zenodo.5894252.

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Department of Pharmaceutical Sciences, Nagpur University Campus, Nagpur-440 010 <em>Manuscript received 17 February 1993, accepted 4 May 1993</em> Synthesis and Antiinflammatory Activity of Substituted 2-Amino-4-carboxy-5-thiazoleacetic Acids.  

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25

Gein, V. L., O. V. Bobrovskaya, I. V. Kovtonogova, et al. "Synthesis of methyl 4-aryl-2-{[4-(carbamimidoylsulfamoyl)- phenyl]amino}-4-oxobut-2-enoates." Russian Journal of Organic Chemistry 52, no. 12 (2016): 1762–64. http://dx.doi.org/10.1134/s1070428016120083.

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26

D.T.Tayade*, R. D. Thombare S.A. Waghmare. "SYNTHESIS OF 3-[4-AMINO-N-SUBSTITUTED-o-ANISAMIDO- 5-YL]AMINO-5-SUBSTITUTED-1,2,4-DITHIAZOLE." Indo American Journal of Pharmaceutical Sciences 04, no. 10 (2017): 3890–94. https://doi.org/10.5281/zenodo.1035231.

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A novel series of 3-{4-Amino-N-[2-(dithethylamino)ethyl-o-anisamido-5-yl}amino-5-substitutedimino-1,2,4- dithiazole was synthesized by the oxidative cyclization of 4-amino-5-substituteddithiobiureto-N-[2- (dithethylamino)ethyl-o-anisamide in chloroform medium by making the use of liquid bromine as oxidizing agent. The products were characterized and justified on the basis of elemental analysis, chemical characteristics and spectral studies. Keywords:3-{4-Amino-N-[2-(dithethylamino)ethyl-o-anisamido-5-yl}amino-5-substituted -imino-1,2,4-dithiazole, 4- amino-5-substituteddithiobiureto-N-[2-(dith

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27

Pilotzi-Xahuentitla, Hugo, Gabriela Canche-Naal, Rolffy Ortiz-Andrade, Gabriel Navarrete-Vázquez, and Emanuel Hernández-Núñez. "N-(Benzothiazol-2-yl)-4-((5-chlorobenzoxazol-2-yl)amino)butanamide." Molbank 2024, no. 3 (2024): M1854. http://dx.doi.org/10.3390/m1854.

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Benzazoles, such as benzoxazoles and benzothiazoles, are compounds with important biological and pharmacological activities and important intermediaries in synthesis. This report presents the synthesis of a butanamide derived from linking 5-chloro-2-aminobenzoxazole and 2-aminobenzothiazole via 4-chlorobutanoyl chloride. The corresponding compound N-(benzothiazol-2-yl)-4-((5-chlorobenzoxazol-2-yl)aminobutanamide was obtained at a 76% global yield using accessible starting materials and a methodology in two reaction steps. Furthermore, we conducted docking studies of this compound on 3-TOP prot

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28

Guna, J. V., V. N. Bhadani, H. D. Purohit, and Dipak M. Purohit. "Synthesis and Antimicrobial Activity of (2-Methoxy/2-Amino)-6-{4'-[(4'''-Chlorophenyl) (Phenyl) Methyl Amino] Phenyl}-4-Aryl Nicotinonitrile." International Letters of Chemistry, Physics and Astronomy 49 (April 2015): 99–103. http://dx.doi.org/10.18052/www.scipress.com/ilcpa.49.99.

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2- Methoxy – 6 - {4' - [(4'''- Chlorophenyl) (phenyl) methyl amino] phenyl} - 4 - aryl nicotinonitrile (3a-3l) and 2-Amino-6-{4'-[(4'''-Chlorophenyl)(phenyl)methyl amino]phenyl}-4-aryl nicotinonitrile (4a-4l) have been synthesized. The products have been assayed for their antimicrobial activity against Gram +ve, Gram -ve bacteria and fungi. The structure of the products has been elucidated by IR, 1H-NMR, mass spectral data, elemental analysis and thin layer chromatography.

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29

Guna, J. V., V. N. Bhadani, H. D. Purohit, and Dipak M. Purohit. "Synthesis and Antimicrobial Activity of (2-Methoxy/2-Amino)-6-{4'-[(4'''-Chlorophenyl) (Phenyl) Methyl Amino] Phenyl}-4-Aryl Nicotinonitrile." International Letters of Chemistry, Physics and Astronomy 49 (April 7, 2015): 99–103. http://dx.doi.org/10.56431/p-j98lcy.

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2- Methoxy – 6 - {4' - [(4'''- Chlorophenyl) (phenyl) methyl amino] phenyl} - 4 - aryl nicotinonitrile (3a-3l) and 2-Amino-6-{4'-[(4'''-Chlorophenyl)(phenyl)methyl amino]phenyl}-4-aryl nicotinonitrile (4a-4l) have been synthesized. The products have been assayed for their antimicrobial activity against Gram +ve, Gram -ve bacteria and fungi. The structure of the products has been elucidated by IR, 1H-NMR, mass spectral data, elemental analysis and thin layer chromatography.

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30

Resnyanskaya, E. V., A. V. Tverdokhlebov, A. A. Tolmachev, and Yu M. Volovenko. "Synthesis of 5-Amino-4-(4-aryl-2-thiazolyl)-2,3-Dihydro-2-Pyrrolones." Russian Journal of Organic Chemistry 41, no. 2 (2005): 257–60. http://dx.doi.org/10.1007/s11178-005-0153-7.

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31

Journal, Baghdad Science. "Synthesis of some Schiff's bases derivatives from aminoazo compounds." Baghdad Science Journal 4, no. 3 (2007): 416–19. http://dx.doi.org/10.21123/bsj.4.3.416-419.

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Reaction of,2- [( 4- amio phenyl ) diazenyl] 1,3,4- thiadiazole -5- thiol (S1) with p- chlorobenzeldehyde,3,4 – dimethoxy benzaldehyde and pyrrol-2- carbonxaldehyde gave -5- [{4-(4-chlorobenzylidene amino) phenyl} diezenyl]-1,3,4- thiadiazole-2- thiol (S2),5-[{ 4-[(3,4- dimethoxybenzyldene )amino phenyl ] diazenyl)-1,3,4- thiadiazole-2-thiol,(S3) and -5- [4-(1,H – pyrrol -2- yl- methylene)amino phenyl] diazenyl)-1,3,4- thiadiazole-2- thiol (S4) respectively as schiff's bases compounds. On the same route-2-[(4-amino-1- naphthyl ) diazenyl] -1,3,4- thiadiazole -5- thiol (S5) reacts with –p- chlo

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32

Murat Saracoglu, Murat Saracoglu, Zulbiye Kokbudak Zulbiye Kokbudak, and M. Izzettin Yilmazer and Fatma Kandemirli M Izzettin Yilmazer and Fatma Kandemirli. "Synthesis and DFT Studies of Pyrimidin-1(2H)-ylaminofumarate Derivatives." Journal of the chemical society of pakistan 42, no. 5 (2020): 746. http://dx.doi.org/10.52568/000679.

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Pyrimidine derivatives have biological and pharmacological properties. Therefore, in this study we focused on the synthesis various Pyrimidine derivatives to make noteworthy contributions this class of heterocyclic compounds. In the present study, the new compounds (4-6) were obtained by the reactions of 1-amino-5-benzoyl-4-phenylpyrimidin-2(1H)-one (1), 1-amino-5-(4-methylbenzoyl)-4-(4-methylphenyl)pyrimidin-2(1H)-one (2) and 1-amino-5-(4-methoxybenzoyl)-4-(4-methoxyphenyl)pyrimidin-2(1H)-one (3) with dimethyl acetylenedicarboxylate. The structures of these compounds were proved by elemental

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33

Murat Saracoglu, Murat Saracoglu, Zulbiye Kokbudak Zulbiye Kokbudak, and M. Izzettin Yilmazer and Fatma Kandemirli M Izzettin Yilmazer and Fatma Kandemirli. "Synthesis and DFT Studies of Pyrimidin-1(2H)-ylaminofumarate Derivatives." Journal of the chemical society of pakistan 42, no. 5 (2020): 746. http://dx.doi.org/10.52568/000679/jcsp/42.05.2020.

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Pyrimidine derivatives have biological and pharmacological properties. Therefore, in this study we focused on the synthesis various Pyrimidine derivatives to make noteworthy contributions this class of heterocyclic compounds. In the present study, the new compounds (4-6) were obtained by the reactions of 1-amino-5-benzoyl-4-phenylpyrimidin-2(1H)-one (1), 1-amino-5-(4-methylbenzoyl)-4-(4-methylphenyl)pyrimidin-2(1H)-one (2) and 1-amino-5-(4-methoxybenzoyl)-4-(4-methoxyphenyl)pyrimidin-2(1H)-one (3) with dimethyl acetylenedicarboxylate. The structures of these compounds were proved by elemental

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34

LALLAN, MISHRA, and K. SAID MUSTAFA. "Synthetic and Solid State Structural Studies of Iron(II) and Iron(III) Complexes incorporating 1,3-Bis( aceto )benzimidazolin-2-thione and Heterocyclic Amines." Journal of Indian Chemical Society Vol. 70, Nov-Dec 1993 (1993): 981–85. https://doi.org/10.5281/zenodo.5948306.

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Department of Chemistry, Banaras Hindu University, Varanasi-221 005 <em>Manuscript received 30 July 1993</em> 1,3-Bis(aceto)benzimidazolin-2-thione (L<sup>1</sup>) was condensed with 2-amino-5-mercapto-1,3,4-thiadiazole (L<sup>2</sup>), 2-amino -5-phenyl-1,3,4-thiadiazole (L<sup>3</sup>), 2-amino-5-<em>o</em>-hydroxyphenyl-1,3,4-oxadiazole (L<sup>4</sup>) and 4-amino-3-mercapto-5-phenyl-1,2,4-triazole (L<sup>5</sup>) followed by addition of Fe<sup>II</sup>/Fe<sup>III </sup>salts. The solid complexes thus isolated were characterised by elemental analysis, spectral (ir, electronic, esr and Mossb

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35

Vasil'ev, L. S., F. E. Surzhikov, O. G. Azarevich, V. S. Bogdanov, and V. A. Dorokhov. "Synthesis of 4-hydroxy- and 3-aryl-4-amino- 2-trifluoromethylpyridines." Russian Chemical Bulletin 45, no. 11 (1996): 2574–77. http://dx.doi.org/10.1007/bf01431118.

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36

Chorbadjiev, S., Ch Ivanov, and B. Moskova. "Synthesis of 2-Amino-4-Aryl-3-(1-Aziridinylmethyl)-and 2-Amino-4-Aryl-3-(1-Pyperidylmethyl)Quinolines." Synthetic Communications 17, no. 11 (1987): 1363–71. http://dx.doi.org/10.1080/00397918708057758.

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37

Abbenante, G., and RH Prager. "Synthesis of 3-Amino-2-(4-chlorophenyl)propanesulfonic Acid (Saclofen) and 3-Amino-2-(4-chlorophenyl)-2-hydroxypropanesulfonic Acid (Hydroxysaclofen)." Australian Journal of Chemistry 43, no. 1 (1990): 213. http://dx.doi.org/10.1071/ch9900213.

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38

Langlois, Nicole, and Julien Massé. "Synthesis of 5-Amino- and 4-Hydroxy-2-phenylsulfonylmethylpiperidines." HETEROCYCLES 77, no. 1 (2009): 417. http://dx.doi.org/10.3987/com-08-s(f)37.

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39

Szczepankiewicz, Wojciech, and Jerzy Suwiński. "Synthesis of 4-arylaminoquinazolines via 2-amino-N-arylbenzamidines." Tetrahedron Letters 39, no. 13 (1998): 1785–86. http://dx.doi.org/10.1016/s0040-4039(97)10864-4.

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40

Kenzhetaeva, S. O., and L. K. Abulyaissova. "Synthesis of 2-amino-4-phenylthiazole-derived thiuram disulfide." Russian Journal of General Chemistry 83, no. 11 (2013): 2115–16. http://dx.doi.org/10.1134/s1070363213110285.

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41

Ha, Hyun-Joon, Young-Gil Ahn, and Gwan Sun Lee. "Asymmetric synthesis of 3-amino-2-hydroxy-4-phenylbutanoate." Tetrahedron: Asymmetry 10, no. 12 (1999): 2327–36. http://dx.doi.org/10.1016/s0957-4166(99)00249-9.

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42

Vasil’ev, L. S., F. E. Surzhikov, and V. A. Dorokhov. "Synthesis of derivatives of 4-amino-2-trifluoromethylnicotinic acid." Russian Chemical Bulletin 53, no. 10 (2004): 2319–21. http://dx.doi.org/10.1007/s11172-005-0120-z.

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43

Sedova, V. F., and O. P. Shkurko. "Synthesis of 6-amino-2-(p-aminophenyl)-4-phenylquinazoline." Chemistry of Heterocyclic Compounds 31, no. 4 (1995): 481–84. http://dx.doi.org/10.1007/bf01177022.

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44

Tverdokhlebov, Anton, Alexander Denisenko, Andrey Tolmachev, Yulian Volovenko, Svitlana Shishkina, and Oleg Shishkin. "Synthesis of 6-Amino-2-bromo-4-hydroxynicotinaldehyde Derivatives." Synthesis 2011, no. 02 (2010): 251–56. http://dx.doi.org/10.1055/s-0030-1258371.

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Zhao, Qian, Han-Geng Chen, Chao Qian, and Xin-Zhi Chen. "Improved Synthesis of 2-Chloro-3-amino-4-methylpyridine." Journal of Heterocyclic Chemistry 50, no. 1 (2013): 145–48. http://dx.doi.org/10.1002/jhet.1052.

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46

Metwally, M. A., Abdelbasset A. Farahat, and Bakr F. Abdel-Wahab. "ChemInform Abstract: 2-Amino-4-thiazolidinones: Synthesis and Reactions." ChemInform 42, no. 9 (2011): no. http://dx.doi.org/10.1002/chin.201109262.

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Dhakoniya, Pallavi. "Synthesis and Characterization of Benzylidene Derivatives of Benzothiazole." International Journal for Research in Applied Science and Engineering Technology 9, no. VIII (2021): 506–11. http://dx.doi.org/10.22214/ijraset.2021.37370.

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A series of some novel benzothiazole derivatives were synthesized from the 2-(4-aminophenyl) benzothiazol-5-ol, which was synthesized by the Jacobson method using Lawesson’s reagent. Benzylidene derivatives (P201-P205) were synthesized by catalyzed condensation and acylation method,named as 2-(4-((4 hydroxybenzylidene)amino) phenyl) benzothiazole-5-ol (P201), 2-(4-((4- methoxybenzylidene) amino)phenyl)benzothiazole-5ol(P202),2-(4-((4-chlorobenzylidene) amino)phenyl)benzothiazole-5-ol(P203), (4-((furan-2-ylmethylene) amino)phenyl)benzothiazole-5-ol(P204), Dimethyl(4(5hydroxy benzothiazol2yl)phe

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48

Pragnesh, B. Rana, A. Patel Jigisha, D. Mistry B., and R. Desai K. "Synthesis of various pharma based pyrido[2,3-d]pyrimidine as well as pyrido[1,2-a]pyrimidine and their antimicrobial activities." Journal of Indian Chemical Society Vol. 87, Mar 2010 (2010): 365–72. https://doi.org/10.5281/zenodo.5779153.

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Department of Chemistry, B. K. M. Science College, Valsad-396 001, Gujarat, India <em>E-mail :</em> bhavana_mistryll@yahoo.co.in <em>Manuscript received 27 October 2008, revised 2 April 2009, accepted 7 August 2009</em> 4-Amino-7-{ 4'-[(4" -methylplperazlnyl)dlazenyl)phenyi}-5-(snbstitutedphenyl)-1<em>H</em>-pyrldo[2,3-d]pyrimldine-2-one (4a-j), 4-amino-7-{4'-[(4"-methylpiperazinyl)diazenyl]phenyi}-5-(substitutedphenyl)-1H-pyrldo[2,3-d]pyrlmldhle-2-thlone (5a-j), 4-thioureido-7-{ if -[(4" -methylpiperazinyl)dlazenyl)phenyl}-5-(substitutedphenyl)-1<em>H</em>-pyrldo[2,3-d]

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G., RAMA RAO, THIRUMALA CHARY M., MOGILAIAH K., SWAMY B., and SREENIVASULU B. "Synthesis of 2-(2-Amino-3-pyridyl)-3-substltutedbenzoylamino-4-thiazolidinones." Journal Of Indian Chemical Society Vol. 66, Jan 1989 (1989): 61–63. https://doi.org/10.5281/zenodo.6131919.

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Department of Chemistry, Kakatiya University, Warangal-506 009 Manuscript <em>received 9 November 1987, revised 11 </em>April <em>1988, accepted 4 October 1988</em> 4-THIAZOLIDINONE derivatives are known to possess a variety of physiological properties<sup>1</sup>. These reports prompted us to synthesise a series of hitherto unreported 2-(2-amino-3-pyridy1)-3-substituted-benzoylamino-4-thiazolidin ones.

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Xuan, Richeng, Weixiao Hu, and Zhongyu Yang. "One-Pot Synthesis ofdl-2-Amino-2-thiazoline-4-carboxylic Acid." Synthetic Communications 33, no. 7 (2003): 1109–12. http://dx.doi.org/10.1081/scc-120017133.

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