Relevant bibliographies by topics / Tyrosinase inhibition activity

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Tyrosinase inhibition activity'

Author: Grafiati
Published: 4 June 2025
Last updated: 1 August 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Tyrosinase inhibition activity.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "Tyrosinase inhibition activity"

1

Suwunwong, T., T. Kobkeatthawin, K. Chanawanno, N. Saewan, P. Wisitsak, and Suchada Chantrapromma. "Tyrosinase Inhibitory Activity of Pyrazole Derivatives." Advanced Materials Research 506 (April 2012): 194–97. http://dx.doi.org/10.4028/www.scientific.net/amr.506.194.

Full text
Abstract:
A series of 3,5-substituted-4,5-dihydro-1H-pyrazole-1-carbothioamide derivatives were synthesized. Their structures were determined on the basis of spectroscopic data interpretation and their tyrosinase inhibitory activity was determined. The results showed that compound 2 (at 1.00 mg/mL) exhibits significant tyrosinase inhibitory activity with % inhibition of 91.866 ± 2.086 with L-tyrosine as substrate whereas compound 3 (at 1.00 mg/mL) exhibits significant tyrosinase inhibitory activity with % inhibition of 79.266 ± 0.552 and 89.593 ± 1.015 with L-tyrosine and L-DOPA as substrates. The IC50v
APA, Harvard, Vancouver, ISO, and other styles
2

Kubo, Isao, Qing-Xi Chen, Ken-Ichi Nihei, José S. Calderón, and Carlos L. Céspedes. "Tyrosinase Inhibition Kinetics of Anisic Acid." Zeitschrift für Naturforschung C 58, no. 9-10 (2003): 713–18. http://dx.doi.org/10.1515/znc-2003-9-1021.

Full text
Abstract:
AbstractAnisic acid (p-methoxybenzoic acid) was characterized as a tyrosinase inhibitor from aniseed, a common food spice. It inhibited the oxidation of l-3,4-dihydroxyphenylalanine (ʟ- DOPA) catalyzed by tyrosinase with an IC50 of 0.60 mᴍ. The inhibition of tyrosinase by anisic acid is a reversible reaction with residual enzyme activity. This phenolic acid was found to be a classical noncompetitive inhibitor and the inhibition constant KI was obtained as 0.603 mᴍ. Anisic acid also inhibited the hydroxylation of ʟ-tyrosine catalyzed by tyrosinase. The lag phase caused by the monophenolase acti
APA, Harvard, Vancouver, ISO, and other styles
3

Hwang, YeJi, Jieun Lee, Hee Jin Jung, et al. "A Novel Class of Potent Anti-Tyrosinase Compounds with Antioxidant Activity, 2-(Substituted phenyl)-5-(trifluoromethyl)benzo[d]thiazoles: In Vitro and In Silico Insights." Antioxidants 11, no. 7 (2022): 1375. http://dx.doi.org/10.3390/antiox11071375.

Full text
Abstract:
Sixteen compounds bearing a benzothiazole moiety were synthesized as potential tyrosinase inhibitors and evaluated for mushroom tyrosinase inhibitory activity. The compound 4-(5-(trifluoromethyl)benzo[d]thiazol-2-yl)benzene-1,3-diol (compound 1b) exhibited the highest tyrosinase activity inhibition, with an IC50 value of 0.2 ± 0.01 μM (a potency 55-fold greater than kojic acid). In silico results using mushroom tyrosinase and human tyrosinase showed that the 2,4-hydroxyl substituents on the phenyl ring of 1b played an important role in the inhibition of both tyrosinases. Kinetic studies on mus
APA, Harvard, Vancouver, ISO, and other styles
4

Goenka, Shilpi, Francis Johnson, and Sanford R. Simon. "Novel Chemically Modified Curcumin (CMC) Derivatives Inhibit Tyrosinase Activity and Melanin Synthesis in B16F10 Mouse Melanoma Cells." Biomolecules 11, no. 5 (2021): 674. http://dx.doi.org/10.3390/biom11050674.

Full text
Abstract:
Skin hyperpigmentation disorders arise due to excessive production of the macromolecular pigment melanin catalyzed by the enzyme tyrosinase. Recently, the therapeutic use of curcumin for inhibiting tyrosinase activity and production of melanin have been recognized, but poor stability and solubility have limited its use, which has inspired synthesis of curcumin analogs. Here, we investigated four novel chemically modified curcumin (CMC) derivatives (CMC2.14, CMC2.5, CMC2.23 and CMC2.24) and compared them to the parent compound curcumin (PC) for inhibition of in vitro tyrosinase activity using t
APA, Harvard, Vancouver, ISO, and other styles
5

No, Jae Kyung, Min Sun Kim, You Jung Kim, Song Ja Bae, Jae Sue Choi, and Hae Young Chung. "Inhibition of Tyrosinase by Protocatechuic Aldehyde." American Journal of Chinese Medicine 32, no. 01 (2004): 97–103. http://dx.doi.org/10.1142/s0192415x04001801.

Full text
Abstract:
The purpose of this study was to determine the inhibitory action of protocatechuic aldehyde (PCA) on tyrosinase activity. PCA is one of the compounds found in the root of Salvia miltiorrhiza. Our study documented that PCA has a potent inhibitory effect on tyrosinase, which catalyzes the rate-limiting step of melanin biosynthesis. Although melanin biosynthesis has an essential function normally in human skin for defense against ultraviolet light of the sun, its abnormal activity as seen in pigmentation disorder could lead to serious medical problems. Our data showed that PCA, with concentration
APA, Harvard, Vancouver, ISO, and other styles
6

Thailan, V., M. Parvadhavardhani, M. Geethalakshmi, and S. Jayashree. "Extraction of Barleria prionitis (root) and evaluation of tyrosinase inhibition activity." Research Journal of Biotechnology 20, no. 4 (2025): 33–40. https://doi.org/10.25303/204rjbt033040.

Full text
Abstract:
The present study evaluated the tyrosinase inhibition activity and antioxidant activity for Vitiligo (pale white patches) disease by using Barleria prionitis (root) extracts with solvent extracts of ethyl acetate. The tyrosinase inhibition activity of the extracts was determined by inhibition concentration (IC50 values). Results showed that ethyl acetate had the highest tyrosinase inhibition activity by decreasing the percentage of inhibition concentration. The extracts' antioxidant activities were assessed by scavenging 1,1-diphenyl-2- picrylhydrazyl radicals (DPPH test). The results showed t
APA, Harvard, Vancouver, ISO, and other styles
7

Lee, Sanggwon, Heejeong Choi, Yujin Park, et al. "Urolithin and Reduced Urolithin Derivatives as Potent Inhibitors of Tyrosinase and Melanogenesis: Importance of the 4-Substituted Resorcinol Moiety." International Journal of Molecular Sciences 22, no. 11 (2021): 5616. http://dx.doi.org/10.3390/ijms22115616.

Full text
Abstract:
We previously reported (E)-β-phenyl-α,β-unsaturated carbonyl scaffold ((E)-PUSC) played an important role in showing high tyrosinase inhibitory activity and that derivatives with a 4-substituted resorcinol moiety as the β-phenyl group of the scaffold resulted in the greatest tyrosinase inhibitory activity. To examine whether the 4-substituted resorcinol moiety could impart tyrosinase inhibitory activity in the absence of the α,β-unsaturated carbonyl moiety of the (E)-PUSC scaffold, 10 urolithin derivatives were synthesized. To obtain more candidate samples, the lactone ring in synthesized urol
APA, Harvard, Vancouver, ISO, and other styles
8

Huang, Yaru, Jiefang Yang, Yunyang Chi, et al. "Newly Designed Quinazolinone Derivatives as Novel Tyrosinase Inhibitor: Synthesis, Inhibitory Activity, and Mechanism." Molecules 27, no. 17 (2022): 5558. http://dx.doi.org/10.3390/molecules27175558.

Full text
Abstract:
We synthesized a series of quinazolinone derivates as tyrosinase inhibitors and evaluated their inhibition constants. We synthesized 2-(2,6-dimethylhepta-1,5-dien-1-yl)quinazolin-4(3H)-one (Q1) from the natural citral. The concentration, which led to 50% activity loss of Q1, was 103 ± 2 μM (IC50 = 103 ± 2 μM). Furthermore, we considered Q1 to be a mixed-type and reversible tyrosinase inhibitor, and determined the KI and KIS inhibition constants to be 117.07 μM and 423.63 μM, respectively. Our fluorescence experiment revealed that Q1 could interact with the substrates of tyrosine and L-DOPA in
APA, Harvard, Vancouver, ISO, and other styles
9

Batubara, Irmanida, Maily Mustofa, Wulan Tri Wahyuni, et al. "Tyrosinase Inhibition, Antiglycation, and Antioxidant Activity of Xylocarpus granatum." Biosaintifika: Journal of Biology & Biology Education 12, no. 1 (2020): 70–75. http://dx.doi.org/10.15294/biosaintifika.v12i1.22676.

Full text
Abstract:
Xylocarpus granatum is mangrove plant that traditionally used as face powder in Central Sulawesi, Indonesia which related to antioxidant, antiglycation and tyrosinase inhibition activities. This study aimed to evaluate the potency of X. granatum as a tyrosinase inhibitor, antiglycation, and antioxidant. The leaves, stem, stem bark, fruit flesh, fruit peel, and kernel of X. granatum were extracted using ethanol then their tyrosinase inhibition, antiglycation, and antioxidant were evaluated. Tyrosinase inhibition activity was evaluated using in vitro assay with L-tyrosine and L-DOPA as the subst
APA, Harvard, Vancouver, ISO, and other styles
10

Fatharani, Raihana Mufliha, Ula Aulia Fitrian, Sumail Sidik Ode Ishak, and Amirah Adlia. "Sun protection factor and tyrosinase inhibitory activity of several plant secondary metabolites." Current Research on Biosciences and Biotechnology 5, no. 1 (2023): 315–19. http://dx.doi.org/10.5614/crbb.2023.5.1/vclq3adv.

Full text
Abstract:
Severe exposure to ultraviolet (UV) rays leads to skin damage, including hyperpigmentation, freckles, melanoma, age spots, and melasma, all of which are related to the skin pigment enzyme, tyrosinase. Prevention can be achieved by avoiding harsh UV rays and inhibiting tyrosinase catalytic activity. Many compounds have been developed for the treatment of such conditions; however, most come with unwanted side effects. The purpose of this study was to determine the sun protection factor (SPF) value and tyrosinase enzyme inhibitory activity of plant secondary metabolites with high antioxidant acti
APA, Harvard, Vancouver, ISO, and other styles
More sources

Dissertations / Theses on the topic "Tyrosinase inhibition activity"

1

Hossain, Abzal. "Inhibition of tyrosinase activity by metallothionein from Aspergillus niger." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0015/MQ55068.pdf.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Narli, Isil. "Activity Analysis Of Immobilized Tyrosinase In The Presence Of Different Inhibitors." Master's thesis, METU, 2006. http://etd.lib.metu.edu.tr/upload/2/12607238/index.pdf.

Full text
Abstract:
ACTIVITY ANALYSIS OF IMMOBILIZED TYROSINASE ENZYME IN THE PRESENCE OF DIFFERENT INHIBITORS Narli, ISil M.Sc., Department of Chemistry Supervisor: Prof. Dr. Levent Toppare May 2006, 97 pages Immobilization of tyrosinase enzyme was performed in the matrices obtained via copolymerization of terephthalic acid bis-(2-thiophen-3-yl ethyl) ester (TATE) with pyrrole. During electrochemical polymerization of pyrrole, enzyme molecules were entrapped in the copolymer matrice. Activity measurements were performed by using Besthorn&amp<br>#8217<br>s Hydrazone method which includes spectrophotometri
APA, Harvard, Vancouver, ISO, and other styles
3

Juneja, Kashmir Singh. "Tyrosinase-like activity of several Alzheimer's disease related and model peptides and their inhibition by natural antioxidants." [Tampa, Fla] : University of South Florida, 2006. http://purl.fcla.edu/usf/dc/et/SFE0001838.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Seaton, Angela. "Anti-tumour activity of novel phenolic compounds." Thesis, University of Nottingham, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.324524.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

White, Kylie Suzanne, та kyes_w@yahoo com. "The antimicrobial mechanism of action of 3,4-methylenedioxy-β-nitropropene". RMIT University. Applied Sciences, 2009. http://adt.lib.rmit.edu.au/adt/public/adt-VIT20090723.101430.

Full text
Abstract:
This research investigated the mechanism of action in bacteria of 3,4-methylenedioxy-β-nitropropene (BDM-I), a very broad spectrum antimicrobial lead compound in development as an anti-infective drug. The thesis proposes that BDM-I inhibits bacterial protein tyrosine phosphatases, a novel mechanism of action for an antimicrobial agent and a new target in microorganisms. This very open investigation was directed by considerable biological information on the effects of BDM-I in microorganisms and animals which provided insights into possible and improbable cellular targets. The biological ef
APA, Harvard, Vancouver, ISO, and other styles
6

Yunus, Madiha. "Investigating the Effect of Regorafenib on the Expression and Activity of the Angiogenesis-Modulating Receptor Tyrosine Kinases." Thesis, The University of Sydney, 2022. https://hdl.handle.net/2123/29860.

Full text
Abstract:
The past two decades have been vital for developing cancer treatments. Even though traditional chemotherapy remains the primary choice for most oral treatment regimens, the cancer treatment paradigm is shifting towards more personalised, mechanism-based and selective therapeutic strategies. Tremendous advances have been made in understanding the aberrant signal transduction pathways in cancer, and a myriad of oncogenic drivers have been identified as promising candidates for molecule-targeted therapies. By using small low-molecular-weight compounds, specific alterations in oncogenic molecules
APA, Harvard, Vancouver, ISO, and other styles
7

Ren, Huan. "Biological activity of the 2-phenylaminopyrimidine class receptor tyrosine kinase inhibitor imatinib mesylate (STI571) in malignant glioma." Thesis, University of Liverpool, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.419008.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Tran, Amanda P. "Modulation of Receptor Protein Tyrosine Phosphatase Sigma Enhances Protease Activity to Relieve Chondroitin Sulfate Proteoglycan Inhibition of Peripheral Axons and Oligodendrocytes." Case Western Reserve University School of Graduate Studies / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=case1528450936899252.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Dool, Carly Jade 1985. "Pharmacologic inhibition of insulin receptor tyrosine kinase activity has antineoplastic effects similar to alloxan-induced insulin deficiency with less acute metabolic toxicity." Thesis, McGill University, 2009. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=111555.

Full text
Abstract:
Recent population studies provide evidence that individuals with high circulating insulin levels have a poor prognosis and/or increased risk of cancer development; however, laboratory studies concerning the role of insulin in breast cancer biology are sparse. We compared the growth of 4T1 murine breast cancer allografts in control mice, alloxan-induced hypoinsulinemic mice, and mice treated with the insulin/insulin-like growth factor-1 receptor tyrosine kinase inhibitor BMS-536924. Both interventions significantly decreased tumor growth versus control and decreased pathway activation downstrea
APA, Harvard, Vancouver, ISO, and other styles
10

Nguyen, Van tai. "Physiopathologie des toxicités hématologiques et vasculaires des inhibiteurs de récepteurs à activité tyrosine kinase anti-angiogénique dans le traitement du cancer." Electronic Thesis or Diss., Paris 13, 2025. http://www.theses.fr/2025PA131002.

Full text
Abstract:
Les inhibiteurs de tyrosine kinase anti-angiogéniques (ITK) sont devenus des médicaments majeurs pour le traitement de divers types de cancer, mais leur utilisation est associée à une incidence élevée de toxicités sévères, notamment des toxicités hématologiques, telles que l'anémie sévère. Des différences considérables ont été observées entre les différents ITKs.Dans cette thèse, nous avons réalisé une méta-analyse afin d'évaluer plus efficacement la prévalence des toxicités des différents ITK anti-angiogéniques chez les patients atteints de cancer, ainsi que dans des sous-populations spécifiq
APA, Harvard, Vancouver, ISO, and other styles
More sources

Books on the topic "Tyrosinase inhibition activity"

1

Fleischmann, Roy. Signalling pathway inhibitors. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199642489.003.0081.

Full text
Abstract:
Oral, small-molecule signalling pathway inhibitors, including ones that inhibit the JAK and SyK pathways, are currently in development for the treatment of rheumatoid arthritis (RA). Tofacitinib is an orally administered small-molecule inhibitor that targets the intracellular Janus kinase 3 and 1 (JAK1/3) molecules to a greater extent than JAK2 while baricitinib (formerly INCB028050) predominantly inhibits JAK1/2. Many of the proinflammatory cytokines implicated in the pathogenesis of RA utilize cell signalling that involves the JAK-STAT pathways and therefore inhibition of JAK-STAT signalling
APA, Harvard, Vancouver, ISO, and other styles
2

Stafstrom, Carl E., and Thomas P. Sutula. 2-Deoxyglucose. Edited by Dominic P. D’Agostino. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190497996.003.0036.

Full text
Abstract:
Metabolic regulation of excitability is increasingly appreciated as a strategy to control seizures and reduce pathogenesis. Inhibiting or bypassing glycolysis may be one way in which the ketogenic diet suppresses seizures. 2-deoxy-D-glucose (2DG) is a glucose analog that partially inhibits glycolysis and has antiseizure effects in several acute and chronic seizure models. The mechanisms underlying the acute and chronic effects of 2DG are being investigated. Preliminary studies provide evidence that the acute anticonvulsant actions of 2DG involve activity-dependent presynaptic suppression of ex
APA, Harvard, Vancouver, ISO, and other styles
3

Eisen, Tim. The patient with renal cell cancer. Edited by Giuseppe Remuzzi. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199592548.003.0172.

Full text
Abstract:
Renal cancer is the commonest malignancy of the kidney and worldwide, accounts for between 2% and 3% of the total cancer burden. The mainstay of curative treatment remains surgery. There have been significant advances in surgical technique, the most important ones being nephron-sparing surgery and laparoscopic nephrectomy. The medical treatment of advanced renal cell cancer has only improved markedly in the last decade with the development of antiangiogenic tyrosine-kinase inhibitors, inhibitors of mammalian target of rapamycin, and a diminished role for immunotherapy.Tyrosine-kinase inhibitor
APA, Harvard, Vancouver, ISO, and other styles

Book chapters on the topic "Tyrosinase inhibition activity"

1

Pfeifer, K., M. H. Kreuter, R. Steffen, H. C. Schröder, and W. E. G. Müller. "(+)-Aeroplysinin-l: an Inhibitor of Intrinsic Protein Tyrosine Kinase Activity of EGF-Receptor-Kinase Complex." In Cell and Tissue Culture Models in Dermatological Research. Springer Berlin Heidelberg, 1993. http://dx.doi.org/10.1007/978-3-642-77817-9_33.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Heimovaara-Dijkstra, S., T. J. F. Nieland, R. M. van der Meulen, and M. Wang. "Abscisic acid-induced gene-expression requires the activity of protein(s) sensitive to the protein-tyrosine phosphatase inhibitor phenylarsine oxide." In Plant Hormone Signal Perception and Transduction. Springer Netherlands, 1996. http://dx.doi.org/10.1007/978-94-009-0131-5_24.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Ambarwati, Neneng Siti Silfi, and Asya Aulia Nifa. "Tyrosinase Inhibition and Anti-elastase Activity of Leaves and Stem Bark Extract of Garcinia daedalanthera Pierre." In Current Topics on Chemistry and Biochemistry Vol. 6. B P International (a part of SCIENCEDOMAIN International), 2022. http://dx.doi.org/10.9734/bpi/ctcb/v6/3149c.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Acharya, Ritwik, Trisha Bagchi, and Debnirmalya Gangopadhyay. "Mulberry as a Valuable Resource for Food and Pharmaceutical Industries: A Review." In Medicinal Plants [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.104631.

Full text
Abstract:
Mulberry is a fast growing hardy perennial woody plant belonging to the genus Morus of the family Moraceae. There are more than 60 species of the genus Morus found in the subtropical, tropical and temperate regions of Asia, Africa and North America. Cultivation of mulberry is highly economical since the leaf produced by mulberry is extensively used for feeding the silkworm, Bombyx mori for silk production. Mulberry possessing valuable nutritional and phytochemical constituents can serve as highly nutritious food for human with high therapeutic values. Mulberry fruit is rich in carbohydrate, pr
APA, Harvard, Vancouver, ISO, and other styles
5

Koli, Preeti, and Rajesh K. Singh. "Progress in Nitrogen and Sulphur-based Heterocyclic Compounds for their Anticancer Activity." In Key Heterocyclic Cores for Smart Anticancer Drug–Design Part II. BENTHAM SCIENCE PUBLISHERS, 2022. http://dx.doi.org/10.2174/9789815040043122020006.

Full text
Abstract:
Cancer is a widespread disease worldwide. Researchers and scientists have been giving much attention to the drug design and drug discovery of nitrogen (N) and sulfur (S)-based heterocyclic compounds in the last decade. These heteroatoms containing heterocyclic compounds have an imperative role in medicinal chemistry in developing new anticancer drugs. These N and S-based heterocyclic compounds such as pyrrole, quinazoline, thiadiazole, and quinoline are widely used in the rational drug design for anticancer drugs with a favorable therapeutic index. They inhibit the cancerous cells by different
APA, Harvard, Vancouver, ISO, and other styles
6

"C." In Genetic variants and strains of the Laboratory mouse, edited by Mary F. Lyon, Sohaila Rastan, and S. D. M. Brown. Oxford University PressOxford, 1996. http://dx.doi.org/10.1093/oso/9780198548690.003.0005.

Full text
Abstract:
Abstract The albino locus affects the amount of tyrosinase in pigment cells, but does not interfere with the production of pigment cells themselves (3, 40). It seems to be generally accepted that it is. the structural locus for tyrosinase (25, 26, 47) (see Tyr). However, some c locus mutations may not affect tyrosinase enzyme structure (44), suggesting that the locus may control an inhibitor of tyrosinase (19). All the mutant alleles are recessive to wild type in appearance, but heterozygotes with wild type produce intermediate amounts of tyrosinase (3). Albino-locus mutants with lightly pigme
APA, Harvard, Vancouver, ISO, and other styles
7

Rubab, Laila, Ali Irfan, Mohammad Raish, et al. "Targeting Tyrosinase: Heterocyclic Compounds in the Spotlight." In Heterocyclic Chemistry - New Perspectives. IntechOpen, 2024. https://doi.org/10.5772/intechopen.1004439.

Full text
Abstract:
Tyrosinase (TYR) is a multifunctional, glycosylated, copper-containing oxidase and metalloenzyme that falls within the type-3 copper protein family. The primary function of tyrosinase is the catalytic oxidation of two consecutive steps involved in the biosynthesis of melanin. TYR is responsible for the enzymatic browning of fruits and vegetables and hyperpigmentation in human skin, which results in economic loss as well as skin cancer in humans. Consequently, tyrosinase inhibitors (TYRIs) emerge as potential chemotherapeutic skin whitening and browning inhibitors in fruits, as well as anti-mel
APA, Harvard, Vancouver, ISO, and other styles
8

Bracco, Enrico, M. Shahzad Ali, Stefano Magnati, and Giuseppe Saglio. "The Paradigm of Targeting an Oncogenic Tyrosine Kinase: Lesson from BCR-ABL." In Advances in Precision Medicine Oncology. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.97528.

Full text
Abstract:
The aberrant tyrosine phosphorylation, either due to constitutive tyrosine kinases (TKs) or to inactivation of protein tyrosine phosphatases (PTPs), is a widespread feature of many cancerous cells. The BCR-ABL fusion protein, which arises from the Philadelphia chromosome, is a molecular distinct and peculiar trait of some kind of leukemia, namely Chronic Myeloid and Acute Lymphoblastic Leukemia, and displays constitutive tyrosine kinase activity. In the chapter, we will highlight the milestones that had led to the identification of the BCR-ABL fusion gene and its role as the only molecular pat
APA, Harvard, Vancouver, ISO, and other styles
9

Sugunakala, S., and S. Selvaraj. "In silico Approaches to Tyrosine Kinase Inhibitors’ Development." In Marvels of Artificial and Computational Intelligence in Life Sciences. BENTHAM SCIENCE PUBLISHERS, 2023. http://dx.doi.org/10.2174/9789815136807123010014.

Full text
Abstract:
Many cellular communications and cellular activities are regulated by a class of enzyme tyrosine kinases. Mutations or increased expression of these enzymes lead to many proliferative cancers as well as other non-proliferative diseases such as psoriasis, atherosclerosis and some inflammatory diseases. Hence, they are considered vital and prospective therapeutic targets. Over the past decade, considerable research work has been carried out to develop potential inhibitors against these tyrosine kinases. So far, a number of compounds have been identified successfully as tyrosine kinase inhibitors
APA, Harvard, Vancouver, ISO, and other styles
10

Low Wang, Cecilia C., and Boris Draznin. "Insulin Resistance: Molecular Biology and Pathophysiology." In Atypical Diabetes: Pathophysiology, Clinical Presentations, and Treatment Options. American Diabetes Association, 2018. http://dx.doi.org/10.2337/9781580406666.ch02.

Full text
Abstract:
The biologic actions of insulin are mediated via its specific cell surface receptor, which initiates intracellular signaling cascades that ultimately lead to multiple physiologic effects of insulin.(1,2) The insulin receptor possesses an intrinsic tyrosine kinase activity, so interaction of the insulin molecule with the receptor results in autophosphorylation and a subsequent multitude of phosphorylation and dephosphorylation steps to bring about glucose uptake by key target tissues (adipose and skeletal muscle), suppression of lipolysis (in adipose tissue), glycogen synthesis, and inhibition
APA, Harvard, Vancouver, ISO, and other styles

Conference papers on the topic "Tyrosinase inhibition activity"

1

Cvijetić, Ilija, Petar Ristivojević, Maja Krstić-Ristivojević та Dušanka Milojković-Opsenica. "EXPLORING THE POTENTIAL OF Α-ARBUTIN AS THE INHIBITOR OF NEURODEGENERATIVE DISORDERS". У 1st INTERNATIONAL Conference on Chemo and BioInformatics. Institute for Information Technologies, University of Kragujevac, 2021. http://dx.doi.org/10.46793/iccbi21.292c.

Full text
Abstract:
Tyrosinase is an enzyme involved in generation of dopamine-quinones, which has an important role in oxidative stress associated with the Parkinson’s disease. It is also a common molecular target for the design of novel anti-melanogenic agents. The inhibition of tyrosinase might be responsible for the experimentally observed intracellular antioxidant activity of α-arbutin. Moreover, intrinsic radical scavenging capacity of α-arbutin should also be considered. The binding mode of α-arbutin into the active site of Bacillus megaterium tyrosinase is predicted using AutoDock Vina 1.1. To map the the
APA, Harvard, Vancouver, ISO, and other styles
2

Liu, Keshun, and Mike Woolman. "Developing an optimized method for measuring chymotrypsin inhibitor activity in protein products." In 2022 AOCS Annual Meeting & Expo. American Oil Chemists' Society (AOCS), 2022. http://dx.doi.org/10.21748/yucc6741.

Full text
Abstract:
Protease inhibitors of protein nature, such as trypsin inhibitors and chymotrypsin inhibitors, are rich in seeds of legume crops. Soybeans contain Kunitz inhibitor and Bowman-Birk inhibitor. The former mainly inhibits trypsin, while the latter inhibits both trypsin and chymotrypsin. Other legumes contain similar types. Historically, trypsin inhibitor activity in legume products has been of primary interest for measurement due to its antinutritional implication. However, Bowman-Birk inhibitor has been shown therapeutic. It is also more resistant to heat than Kunitz inhibitor. As increasing volu
APA, Harvard, Vancouver, ISO, and other styles
3

Hilhorst, Maria H., Liesbeth Houkes, Rik de Wijn, Matthias Versele, and Rob Ruijtenbeek. "Abstract 650: Response prediction to a multitargeted tyrosine kinase inhibitor by profiling serine/threonine kinase activity and inhibition." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-650.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Buckarma, EeeLN, Nathan Werneburg, Ayano Niibe, Gregory Gores, and Rory Smoot. "Abstract 3449: Tyrosine phosphatase activity is required for response to Src kinase inhibition in cholangiocarcinoma." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.am2019-3449.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Buckarma, EeeLN, Nathan Werneburg, Ayano Niibe, Gregory Gores, and Rory Smoot. "Abstract 3449: Tyrosine phosphatase activity is required for response to Src kinase inhibition in cholangiocarcinoma." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.sabcs18-3449.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Keats, Jeffrey A., Arleide Lee, Jeremy C. Cunniff, et al. "Abstract 1161: EZH2 inhibitor tazemetostat demonstrates activity in preclinical models of Bruton's tyrosine kinase inhibitor-resistant relapsed/refractory mantle cell lymphoma." In Proceedings: AACR Annual Meeting 2021; April 10-15, 2021 and May 17-21, 2021; Philadelphia, PA. American Association for Cancer Research, 2021. http://dx.doi.org/10.1158/1538-7445.am2021-1161.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Matsui, Junji, Yukinori Minoshima, Akihiko Tsuruoka, and Yasuhiro Funahashi. "Abstract 3614: Multi-targeted kinase inhibitor E7080 showed anti-tumor activity against medullary thyroid carcinoma and squamous thyroid carcinoma cell line based on RET and VEGFR2 tyrosine kinase inhibition." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-3614.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Yasuhiro, Tomoko, Toshio Yoshizawa, Shingo Hotta, et al. "Abstract 2452: ONO-4059, a novel oral Bruton's tyrosine kinase (Btk) inhibitor that demonstrates potent pharmacodynamic activity through Phosphorylated Btk (P-Btk) inhibition, in addition to effective anti-tumour activity in a TMD-8 (DLBCL) xenograft model." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-2452.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Ferguson, Peter J., Mark D. Vincent, and James Koropatnick. "Abstract 2019: Synergistic anticancer activity of the RAD51 inhibitor IBR2 with inhibitors of receptor tyrosine kinases and microtubule protein." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-2019.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

LaBonte, Melissa J., Peter M. Wilson, Anthony El-Khoueiry, Heinz-Josef Lenz, and Robert D. Ladner. "Abstract 5438: A novel therapeutic combination with synergistic antitumor activity in colon cancer: The dual tyrosine kinase inhibitor lapatinib and the histone deacetylase inhibitor LBH589." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-5438.

Full text
APA, Harvard, Vancouver, ISO, and other styles

Reports on the topic "Tyrosinase inhibition activity"

1

Dickman, Martin B., and Oded Yarden. Genetic and chemical intervention in ROS signaling pathways affecting development and pathogenicity of Sclerotinia sclerotiorum. United States Department of Agriculture, 2015. http://dx.doi.org/10.32747/2015.7699866.bard.

Full text
Abstract:
Abstract: The long-term goals of our research are to understand the regulation of sclerotial development and pathogenicity in S. sclerotior11111. The focus in this project was on the elucidation of the signaling events and environmental cues involved in the regulation of these processes, utilizing and continuously developing tools our research groups have established and/or adapted for analysis of S. sclerotiorum, Our stated objectives: To take advantage of the recent conceptual (ROS/PPs signaling) and technical (amenability of S. sclerotiorumto manipulations coupled with chemical genomics and
APA, Harvard, Vancouver, ISO, and other styles
You might also be interested in the extended bibliographies on the topic 'Tyrosinase inhibition activity' for particular source types:
Journal articles Dissertations / Theses
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!

To the bibliography