Academic literature on the topic 'U-kappa'

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Journal articles on the topic "U-kappa"

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Imbert, Cyril, Tianling Jin, and Luis Silvestre. "Hölder gradient estimates for a class of singular or degenerate parabolic equations." Advances in Nonlinear Analysis 8, no. 1 (2017): 845–67. http://dx.doi.org/10.1515/anona-2016-0197.

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Abstract We prove interior Hölder estimates for the spatial gradients of the viscosity solutions to the singular or degenerate parabolic equation u_{t}=\lvert\nabla u\rvert^{\kappa}\operatorname{div}(\lvert\nabla u\rvert^{p-% 2}\nabla u), where {p\in(1,\infty)} and {\kappa\in(1-p,\infty)} . This includes the from {L^{\infty}} to {C^{1,\alpha}} regularity for parabolic p-Laplacian equations in both divergence form with {\kappa=0} , and non-divergence form with {\kappa=2-p} .
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McIntosh, T. K., S. Fernyak, I. Yamakami, and A. I. Faden. "Central and systemic kappa-opioid agonists exacerbate neurobehavioral response to brain injury in rats." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 267, no. 3 (1994): R665—R672. http://dx.doi.org/10.1152/ajpregu.1994.267.3.r665.

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The endogenous opioid peptide dynorphin has been implicated in the pathophysiology of secondary tissue injury after central nervous system (CNS) trauma. The detrimental effects of dynorphin appear to be mediated through both opioid receptors (probably kappa-receptors) and nonopioid mechanisms. However, both kappa-opioid agonists and antagonists have been reported to improve outcome in models of CNS trauma. To attempt to clarify this controversy, we examined the effects of centrally or systemically administered kappa-opioid agonists on neurological recovery after experimental fluid-percussion b
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Du, Yihong, Changfeng Gui, Kelei Wang та Maolin Zhou. "Semi-waves with Λ-shaped free boundary for nonlinear Stefan problems: Existence". Proceedings of the American Mathematical Society 149, № 5 (2021): 2091–104. http://dx.doi.org/10.1090/proc/15346.

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We show that for a monostable, bistable or combustion type of nonlinear function f ( u ) f(u) , the Stefan problem \[ { a m p ; u t − Δ u = f ( u ) , u > 0 a m p ; a m p ; for x ∈ Ω ( t ) ⊂ R n + 1 , a m p ; u = 0 and u t = μ | ∇ x u | 2 a m p ; a m p ; for x ∈ ∂ Ω ( t ) , \left \{ \begin {aligned} &u_t-\Delta u=f(u),\; u>0 & &\text {for}~~x\in \Omega (t)\subset \mathbb {R}^{n+1},\\ & u=0~\text {and}~u_t=\mu |\nabla _x u|^2 && \text {for}~~x\in \partial \Omega (t), \end {aligned} \right . \] has a traveling wave solution whose free boundary is Λ \Lambda -shaped, a
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Libermann, T. A., and D. Baltimore. "Activation of interleukin-6 gene expression through the NF-kappa B transcription factor." Molecular and Cellular Biology 10, no. 5 (1990): 2327–34. http://dx.doi.org/10.1128/mcb.10.5.2327.

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The promoter region of the interleukin-6 (IL-6) gene has a putative NF-kappa B-binding site. We found that a fragment of the IL-6 promoter containing the site specifically binds highly purified NF-kappa B protein and the NF-kappa B protein in nuclear extracts of phorbol ester-induced Jurkat cells. Mutations of the NF-kappa B site abolished complex formation with both purified NF-kappa B and the nuclear extract protein. Transient expression of chloramphenicol acetyltransferase (CAT) plasmids containing the IL-6 promoter revealed very little activity of the promoter in U-937 monocytic cells and
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Libermann, T. A., and D. Baltimore. "Activation of interleukin-6 gene expression through the NF-kappa B transcription factor." Molecular and Cellular Biology 10, no. 5 (1990): 2327–34. http://dx.doi.org/10.1128/mcb.10.5.2327-2334.1990.

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The promoter region of the interleukin-6 (IL-6) gene has a putative NF-kappa B-binding site. We found that a fragment of the IL-6 promoter containing the site specifically binds highly purified NF-kappa B protein and the NF-kappa B protein in nuclear extracts of phorbol ester-induced Jurkat cells. Mutations of the NF-kappa B site abolished complex formation with both purified NF-kappa B and the nuclear extract protein. Transient expression of chloramphenicol acetyltransferase (CAT) plasmids containing the IL-6 promoter revealed very little activity of the promoter in U-937 monocytic cells and
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Hui, Chun Yin, та Krishna Kishore. "Torsion elements of order 𝑝2 in the Nottingham group". Journal of Group Theory 23, № 3 (2020): 489–502. http://dx.doi.org/10.1515/jgth-2019-0114.

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AbstractLet κ be a characteristic p finite field of q elements and {\mathfrak{N}_{\kappa}} the Nottingham group over κ. Lubin associated to every conjugacy class of torsion element of {\mathfrak{N}_{\kappa}} a type. We establish an upper bound {B(q;l,m)} on the number of conjugacy classes of order {p^{2}} torsion elements u of {\mathfrak{N}_{\kappa}} of type {\langle l,m\rangle}. In the case where {l<p}, the bound {B(q;l,m)} is the exact number of conjugacy classes. Moreover, we give a criterion on when u and {u^{n}} are conjugate.
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Zhao, Shikai, Jeremiah P. Freeman, Philip F. VonVoigtlander, Martin W. Smith, and Jacob Szmuszkovicz. "Phenalene analogs of the kappa opiate agonist, U-50,488." Bioorganic & Medicinal Chemistry Letters 3, no. 12 (1993): 2641–46. http://dx.doi.org/10.1016/s0960-894x(01)80733-2.

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D'Andrea, Stan V., Eric T. Michalson, Jeremiah P. Freeman, Connie G. Chidester, and Jacob Szmuszkovicz. "trans-3,4-Diaminopiperidines. Azacyclohexane congeners of .kappa. agonist U-50488." Journal of Organic Chemistry 56, no. 9 (1991): 3133–37. http://dx.doi.org/10.1021/jo00009a038.

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Banakh, Taras, Serhii Bardyla, and Oleg Gutik. "The Lawson number of a semitopological semilattice." Semigroup Forum 103, no. 1 (2021): 24–37. http://dx.doi.org/10.1007/s00233-021-10184-z.

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AbstractFor a Hausdorff topologized semilattice X its Lawson number$$\bar{\Lambda }(X)$$ Λ ¯ ( X ) is the smallest cardinal $$\kappa $$ κ such that for any distinct points $$x,y\in X$$ x , y ∈ X there exists a family $$\mathcal U$$ U of closed neighborhoods of x in X such that $$|\mathcal U|\le \kappa $$ | U | ≤ κ and $$\bigcap \mathcal U$$ ⋂ U is a subsemilattice of X that does not contain y. It follows that $$\bar{\Lambda }(X)\le \bar{\psi }(X)$$ Λ ¯ ( X ) ≤ ψ ¯ ( X ) , where $$\bar{\psi }(X)$$ ψ ¯ ( X ) is the smallest cardinal $$\kappa $$ κ such that for any point $$x\in X$$ x ∈ X there ex
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Kavallaris, N. I. "ASYMPTOTIC BEHAVIOUR AND BLOW-UP FOR A NONLINEAR DIFFUSION PROBLEM WITH A NON-LOCAL SOURCE TERM." Proceedings of the Edinburgh Mathematical Society 47, no. 2 (2004): 375–95. http://dx.doi.org/10.1017/s0013091503000658.

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AbstractIn this work, the behaviour of solutions for the Dirichlet problem of the non-local equation$$ u_t=\varDelta(\kappa(u))+\frac{\lambda f(u)}{(\int_{\varOmega}f(u)\,\mathrm{d}x)^p},\quad \varOmega\subset\mathbb{R}^N,\quad N=1,2, $$is studied, mainly for the case where $f(s)=\mathrm{e}^{\kappa(s)}$. More precisely, the interplay of exponent $p$ of the non-local term and spatial dimension $N$ is investigated with regard to the existence and non-existence of solutions of the associated steady-state problem as well as the global existence and finite-time blow-up of the time-dependent solutio
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Dissertations / Theses on the topic "U-kappa"

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Al-Hadad, Mohamed. "Metodjämförelse mellan IMMAGE 800 och BN ProSpec för U-albumin, U-IgG, U-kappa och U-lambda." Thesis, Linnaeus University, School of Natural Sciences, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-8244.

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<p>Njurarna är ett organsystem med viktiga funktioner som exempelvis utsöndring av flertalet vattenlösliga substanser. För att sjukdomssymtom ska uppträda krävs mer än tre fjärdedelars bortfall av njurfunktionen, eftersom njurarna har en enorm reservkapacitet. Genom att analysera bland annat proteinerna albumin, immunoglobulin G, kappa och lambda i urin utreds om njurfunktionen fungerar som den ska. Analys av dessa proteiner kan ske med analysinstrumenten IMMAGE 800 från Beckman Coulter och BN ProSpec från DADE BEHRING. Båda dessa analysinstrument använder sig av metoden nefelometri, som är en
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Dierkes, Birgit. "Die Reduktion der Kontraktionsamplitude elektrisch stimulierter,isolierter ventrikulärer Kardiomyozyten der Ratte durch den kappa-Opioidrezeptoragonisten U-50,488 wird nicht über eine Adenylylcyclase vermittelt." Giessen VVB Laufersweiler, 2010. http://geb.uni-giessen.de/geb/volltexte/2010/7621/index.html.

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Balaños, Guzman Carlos Alberto. "The effects of the kappa agonist U-50,488 on morphine-induced place preference conditioning and Fos immunoreactivity in the preweanling and periadolescent rat." CSUSB ScholarWorks, 1995. https://scholarworks.lib.csusb.edu/etd-project/1074.

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The effects of the kappa opioid agonist U-50,488 on morphine-induced condtioned place preference (CPP), locomotor activity and Fos immunoreactivity and assessed in 10-, 17- and 35-day old rats. It was predicted that kappa agonist treatment would block the unconditioned and conditioned behaviors produced by morhine (a mu opioid receptor agonist).
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Dierkes, Birgit [Verfasser]. "Die Reduktion der Kontraktionsamplitude elektrisch stimulierter,isolierter ventrikulärer Kardiomyozyten der Ratte durch den κ-Opioidrezeptoragonisten [Kappa-Opioidrezeptoragonisten] U-50,488 wird nicht über eine Adenylylcyclase vermittelt / vorgelegt von Birgit Dierkes, geb. Kube". Giessen : VVB Laufersweiler, 2010. http://d-nb.info/1004758367/34.

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Wilson, Willie III Baldwin Albert Sidney. "The regulation of constitutive NF-[kappa]B activity by glycogen synthase kinase-3 in pancreatic cancer." Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2009. http://dc.lib.unc.edu/u?/etd,2458.

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Thesis (Ph. D.)--University of North Carolina at Chapel Hill, 2009.<br>Title from electronic title page (viewed Sep. 3, 2009). "... in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Curriculum in Genetics & Molecular Biology." Discipline: Genetics and Molecular Biology; Department/School: Medicine.
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Green, Adam Geoffrey. "Regulation of TGF-gbs signaling by Xrel3, a member of the Rel/NF-[kappa]B family in human cervical cancer cells / y Adam Geoffrey Green." Internet access available to MUN users only, 2003. http://collections.mun.ca/u?/theses,155720.

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Vu, Ngoc T. "Regulation and Mechanistic Functions of Caspase-9 RNA Splicing." VCU Scholars Compass, 2014. http://scholarscompass.vcu.edu/etd/3578.

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Caspase-9 has two splice variants, pro-apoptotic caspase-9a and anti-apoptotic caspase-9b, and dysregulation of caspase-9 splice variant ratio or expression of caspase-9b isoform has been linked to augmentation of the anchorage-independent growth and tumorigenic capacity of non-small cell lung cancer (NSCLC) cells. This study focuses on cell signaling pathway(s) regulating the alternative splicing of caspase-9 pre-mRNA and mechanistic roles of caspase-9b in a certain oncogenic/survival pathway. In regards to the former, we have identified hnRNP U as a novel splice-enhancer associated with exon
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Sloupenský, Martin. "Variabilita genu kappa-kasein u plemene brown swiss v České republice." Master's thesis, 2017. http://www.nusl.cz/ntk/nusl-430392.

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Kappa-casein has the general function in process of cheese production. Understanding the effect of gene polymorphism of kappa-casein to the nutritional and physical properties of milk may lead to more efficient breeding of dairy cattle. Within this thesis was genotyped by 240 brown swiss and jersey cows determinated using the PCR-RFLP. Then was performed association analysis of the impact of various genotypes on milk production parameters in the program SAS. An association between gene CSN3 polymorphism and milk yield was not statistically significant.
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Chen, Hsin-Yuae, and 陳信岳. "Conformationally Constrained Lactam Analogs of the kappa- Selective Arylacetamide Opioid Analgesic U-50,488." Thesis, 1993. http://ndltd.ncl.edu.tw/handle/14242904183992256927.

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碩士<br>國立臺灣大學<br>藥學研究所<br>81<br>',2'-反式-(3,4-雙氯苯基)-氮-[2'-(氮-pyrrolidinyl)環己基] (4d及4 e)﹐它們是以五環的內醯胺代替U-50,488的醯胺鍵。化合物4d(Ki,k=10 nM)具有比U-50,488(Ki,k=15及約為一半的 ,k=23vs55)在本研究中合成兩 個4d的位置異構物﹐合成路徑中的 H4將2-(3,4-雙氯苯基)丁二酸酐(12) 還原成2-(3,4-雙氯苯基)-r- 3,4-雙氯苯基)-r-丁內酯(20)。20與反 式-2-(氮-pyrrolidinyl)- 劻Q胺醇中間體26及27﹐再經其甲磺酸基衍生 物之環化可得6a及6b﹐ o4d及4e。化合物6a及6b已送測對阿片受器之親和 力。並將這些五 穭綠Q胺類似物鹽酸鹽單晶。送測做x-ray晶體繞射,以 進一步膫解這一類化合物與k阿片受器結合之構造需求。 trans-(d,l)-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)-
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LIN, YI-BIN, and 林怡賓. "Synthesis of lactam and cyclic-imide analogs of U-50, 488 as probes of Kappa opiate receptor." Thesis, 1989. http://ndltd.ncl.edu.tw/handle/74973308254131783800.

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碩士<br>國立臺灣大學<br>中國藥學研究所<br>78<br>U-50.488為美國普強公同所發展出來對Kappa 類嗎啡受器具選擇性親和力的止痛藥。 為了探討這一類化合物與類嗎啡受器結合時,其醯胺支鏈的功能與空間位置我們實驗 室曾合成出以五環醯胺來取代原醯胺鏈接之U-50.488衍生物如(1',2'-trans)-3-phe- nyl-[2'-(N-pyrrolidinyl)cyclohexyl]-2-pyrrolidones(18,19) 便分子中苯環的空 間構形受到限制,由類嗎啡受器親和力試驗知仍對Kappa 受器有很好的選擇性 (約為 U-50.488的1/2),但是親和力約降低為 1/20x。為了推斷其親和力的降低是否因缺乏 苯環3.4-雙氯(dichloro)取代,而導致親脂性降低之故。本研究合成出18及19的苯環 3.4-雙氯取代衍生物,亦即(1',2'-trans)-3-(-3.4-dichloropheny1l)-[2'-(N-pyr- rolidinyl)cyclohexyl]-2-pyrrolidinones(21 及2
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Reports on the topic "U-kappa"

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Dosaka-Akita, Kumi, Frank C. Tortella, John W. Holaday, and Joseph B. Long. The Kappa Opioid Agonist U-50, 488H Antagonizes Respiratory Effects of Mu Opioid Receptor Agonists in Conscious Rats. Defense Technical Information Center, 1993. http://dx.doi.org/10.21236/ada263043.

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