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Journal articles on the topic 'Xiao chi'

Author: Grafiati

Published: 13 December 2022

Last updated: 19 July 2025

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1

Long, Feng-Yao, Li-Wu Qin, Yuan-Pin Xiao, Kevin D. Hyde, Shao-Xian Wang, and Ting-Chi Wen. "Multigene phylogeny and morphology reveal a new species, Ophiocordyceps vespulae, from Jilin Province, China." Phytotaxa 478, no. 1 (2021): 33–48. https://doi.org/10.11646/phytotaxa.478.1.2.

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Long, Feng-Yao, Qin, Li-Wu, Xiao, Yuan-Pin, Hyde, Kevin D., Wang, Shao-Xian, Wen, Ting-Chi (2021): Multigene phylogeny and morphology reveal a new species, Ophiocordyceps vespulae, from Jilin Province, China. Phytotaxa 478 (1): 33-48, DOI: 10.11646/phytotaxa.478.1.2, URL: http://dx.doi.org/10.11646/phytotaxa.478.1.2

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Wijayawardene, Nalin N., Lakmali S. Dissanayake, Qi-Rui Li, et al. "Yunnan-Guizhou Plateau: a mycological hotspot." Phytotaxa 523, no. 1 (2021): 1–31. https://doi.org/10.11646/phytotaxa.523.1.1.

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Wijayawardene, Nalin N., Dissanayake, Lakmali S., Li, Qi-Rui, Dai, Dong-Qi, Xiao, Yuanpin, Wen, Ting-Chi, Karunarathna, Samantha C., Wu, Hai-Xia, Zhang, Huang, Tibpromma, Saowaluck, Kang, Ji-Chuan, Wang, Yong, Shen, Xiang- Chun, Tang, Li-Zhou, Deng, Chun-Ying, Liu, Yanxia, Kang, Yingqian (2021): Yunnan-Guizhou Plateau: a mycological hotspot. Phytotaxa 523 (1): 1-31, DOI: 10.11646/phytotaxa.523.1.1

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3

Li, Da-Wei, Xiao-Peng Deng, Xin He, et al. "Eupholides A H, abietane diterpenoids from the roots of Euphorbia fischeriana, and their bioactivities." Phytochemistry 183 (March 31, 2021): 1–8. https://doi.org/10.1016/j.phytochem.2020.112593.

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Li, Da-Wei, Deng, Xiao-Peng, He, Xin, Han, Xiu-Yan, Ma, Yu-Fang, Huang, Hui-Lian, Yu, Zhen-Long, Feng, Lei, Wang, Chao, Ma, Xiao-Chi (2021): Eupholides A H, abietane diterpenoids from the roots of Euphorbia fischeriana, and their bioactivities. Phytochemistry (112593) 183: 1-8, DOI: 10.1016/j.phytochem.2020.112593, URL: http://dx.doi.org/10.1016/j.phytochem.2020.112593

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4

Zhang, Hao-Miao, Wen-Chi Yeh, and Xiao-Li Tong. "Descriptions of two new species of the genus Planaeschna from China (Odonata: Anisoptera: Aeshnidae)." Zootaxa 2674 (December 31, 2010): 51–60. https://doi.org/10.5281/zenodo.199179.

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Zhang, Hao-Miao, Yeh, Wen-Chi, Tong, Xiao-Li (2010): Descriptions of two new species of the genus Planaeschna from China (Odonata: Anisoptera: Aeshnidae). Zootaxa 2674: 51-60, DOI: 10.5281/zenodo.199179

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Chi, Xiao-Rui, and Long Wang. "Reinstatement of the independent specific status of Chrysanthemum neo-oreastrum (Asteraceae, Anthemideae)." Phytotaxa 571, no. 2 (2022): 227–33. https://doi.org/10.11646/phytotaxa.571.2.9.

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Chi, Xiao-Rui, Wang, Long (2022): Reinstatement of the independent specific status of Chrysanthemum neo-oreastrum (Asteraceae, Anthemideae). Phytotaxa 571 (2): 227-233, DOI: 10.11646/phytotaxa.571.2.9, URL: http://dx.doi.org/10.11646/phytotaxa.571.2.9

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Li, Cheng-Sheng, Xiao-Rui Chi, Wen-Qun Fei, and Chen Ren. "Revisiting the lectotypifications of Senecio plantaginifolius, S. setchuenensis and S. souliei (Asteraceae: Senecioneae)." Phytotaxa 532, no. 1 (2022): 57–66. https://doi.org/10.11646/phytotaxa.532.1.4.

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Li, Cheng-Sheng, Chi, Xiao-Rui, Fei, Wen-Qun, Ren, Chen (2022): Revisiting the lectotypifications of Senecio plantaginifolius, S. setchuenensis and S. souliei (Asteraceae: Senecioneae). Phytotaxa 532 (1): 57-66, DOI: 10.11646/phytotaxa.532.1.4

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7

Tseng, Sung-Hui, Ting-Yi Chien, Chih-Fu Tzeng, Yun-Ho Lin, Chih-Hsiung Wu, and Ching-Chiung Wang. "Prevention of hepatic oxidative injury by Xiao-Chen-Chi-Tang in mice." Journal of Ethnopharmacology 111, no. 2 (2007): 232–39. http://dx.doi.org/10.1016/j.jep.2006.11.030.

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8

Zhou, Wei-Chuan, Qiong Xiao, De-Niu Chen, and Chung-Chi Hwang. "Plectotropis yonganensis sp. nov. (Gastropoda: Bradybaenidae) from China, with revision of two Chinese camaenid species (Gastropoda: Camaenidae)." Zootaxa 2929 (December 31, 2011): 51–56. https://doi.org/10.5281/zenodo.204632.

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Zhou, Wei-Chuan, Xiao, Qiong, Chen, De-Niu, Hwang, Chung-Chi (2011): Plectotropis yonganensis sp. nov. (Gastropoda: Bradybaenidae) from China, with revision of two Chinese camaenid species (Gastropoda: Camaenidae). Zootaxa 2929: 51-56, DOI: 10.5281/zenodo.204632

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9

Peng, Xing-Can, Yuan-Pin Xiao, Yan Zhang, Putarak Chomnunti, Khanobporn Tangtrakulwanich, and Ting-Chi Wen. "Cordyceps poluscapitis sp. nov., an ant-pathogenic fungus from Guizhou, China." Phytotaxa 599, no. 4 (2023): 239–51. https://doi.org/10.11646/phytotaxa.599.4.3.

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Peng, Xing-Can, Xiao, Yuan-Pin, Zhang, Yan, Chomnunti, Putarak, Tangtrakulwanich, Khanobporn, Wen, Ting-Chi (2023): Cordyceps poluscapitis sp. nov., an ant-pathogenic fungus from Guizhou, China. Phytotaxa 599 (4): 239-251, DOI: 10.11646/phytotaxa.599.4.3, URL: http://dx.doi.org/10.11646/phytotaxa.599.4.3

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10

Zhao, Wen-Yu, Jing Yi, Yi-Bo Chang, Cheng-Peng Sun, and Xiao-Chi Ma. "Recent studies on terpenoids in Aspergillus fungi: Chemical diversity, biosynthesis, and bioactivity." Phytochemistry 193 (January 31, 2022): 1–25. https://doi.org/10.1016/j.phytochem.2021.113011.

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Zhao, Wen-Yu, Yi, Jing, Chang, Yi-Bo, Sun, Cheng-Peng, Ma, Xiao-Chi (2022): Recent studies on terpenoids in Aspergillus fungi: Chemical diversity, biosynthesis, and bioactivity. Phytochemistry (113011) 193: 1-25, DOI: 10.1016/j.phytochem.2021.113011, URL: http://dx.doi.org/10.1016/j.phytochem.2021.113011

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Chen, Feng, Chi Xiong, Chang-Bing Zheng, Xiao-Hua Jin, and Hai He. "Cephalanthera yintiaolingensis (Orchidaceae, Epidendroidee, Neottieae), a new mycoheterotrophic orchid from Northeast Chongqing, China." Phytotaxa 626, no. 2 (2023): 119–25. https://doi.org/10.11646/phytotaxa.626.2.5.

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Chen, Feng, Xiong, Chi, Zheng, Chang-Bing, Jin, Xiao-Hua, He, Hai (2023): Cephalanthera yintiaolingensis (Orchidaceae, Epidendroidee, Neottieae), a new mycoheterotrophic orchid from Northeast Chongqing, China. Phytotaxa 626 (2): 119-125, DOI: 10.11646/phytotaxa.626.2.5, URL: https://phytotaxa.mapress.com/pt/article/download/phytotaxa.626.2.5/51301

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12

Wen, Ting-Chi, Ling-Sheng Zha, Yuan-Pin Xiao, Qiang Wang, Ji-Chuan Kang, and Kevin D.Hyde. "Metacordyceps shibinensis sp. nov. from larvae of Lepidoptera in Guizhou Province, southwest China." Phytotaxa 226, no. 1 (2015): 51–62. https://doi.org/10.11646/phytotaxa.226.1.5.

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Wen, Ting-Chi, Zha, Ling-Sheng, Xiao, Yuan-Pin, Wang, Qiang, Kang, Ji-Chuan, D.Hyde, Kevin (2015): Metacordyceps shibinensis sp. nov. from larvae of Lepidoptera in Guizhou Province, southwest China. Phytotaxa 226 (1): 51-62, DOI: 10.11646/phytotaxa.226.1.5, URL: http://dx.doi.org/10.11646/phytotaxa.226.1.5

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13

Wen, Ting-Chi, Yuan-Pin Xiao, Ling-Sheng Zha, Kevin D. Hyde, and Ji-Chuan Kang. "Multigene phylogeny and morphology reveal a new species, Ophiocordyceps tettigonia, from Guizhou Province, China." Phytotaxa 280, no. 2 (2016): 141–51. https://doi.org/10.11646/phytotaxa.280.2.4.

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Wen, Ting-Chi, Xiao, Yuan-Pin, Zha, Ling-Sheng, Hyde, Kevin D., Kang, Ji-Chuan (2016): Multigene phylogeny and morphology reveal a new species, Ophiocordyceps tettigonia, from Guizhou Province, China. Phytotaxa 280 (2): 141-151, DOI: 10.11646/phytotaxa.280.2.4, URL: http://dx.doi.org/10.11646/phytotaxa.280.2.4

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14

Wen, Ting-Chi, Yuan-Pin Xiao, Wen-Jing Li, Ji-Chuan Kang, and Kevin D. Hyde. "Systematic analyses of Ophiocordyceps ramosissimum sp. nov., a new species from a larvae of Hepialidae in China." Phytotaxa 161, no. 3 (2014): 227–34. https://doi.org/10.11646/phytotaxa.161.3.6.

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Wen, Ting-Chi, Xiao, Yuan-Pin, Li, Wen-Jing, Kang, Ji-Chuan, Hyde, Kevin D. (2014): Systematic analyses of Ophiocordyceps ramosissimum sp. nov., a new species from a larvae of Hepialidae in China. Phytotaxa 161 (3): 227-234, DOI: 10.11646/phytotaxa.161.3.6, URL: http://dx.doi.org/10.11646/phytotaxa.161.3.6

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Xiao, Yuan-Pin, Ting-Chi Wen, Sinang Hongsanan, Jing-Zu Sun, and Kevin D. Hyde. "Introducing Ophiocordyceps thanathonensis, a new species of entomogenous fungi on ants, and a reference specimen for O. pseudolloydii." Phytotaxa 328, no. 2 (2017): 115–26. https://doi.org/10.11646/phytotaxa.328.2.2.

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Xiao, Yuan-Pin, Wen, Ting-Chi, Hongsanan, Sinang, Sun, Jing-Zu, Hyde, Kevin D. (2017): Introducing Ophiocordyceps thanathonensis, a new species of entomogenous fungi on ants, and a reference specimen for O. pseudolloydii. Phytotaxa 328 (2): 115-126, DOI: 10.11646/phytotaxa.328.2.2, URL: http://dx.doi.org/10.11646/phytotaxa.328.2.2

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16

Wang, Jian, Shi-Shi Lin, Jun-Shen Gan, et al. "A new species of the genus Boulenophrys from South China (Anura, Megophryidae)." Zootaxa 5514, no. 5 (2024): 451–68. https://doi.org/10.11646/zootaxa.5514.5.3.

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Wang, Jian, Lin, Shi-Shi, Gan, Jun-Shen, Chen, Hong-Hui, Yu, Ling-Min, Pan, Zhong, Xiao, Jia-Jie, Zeng, Zhao-Chi (2024): A new species of the genus Boulenophrys from South China (Anura, Megophryidae). Zootaxa 5514 (5): 451-468, DOI: 10.11646/zootaxa.5514.5.3, URL: http://dx.doi.org/10.11646/zootaxa.5514.5.3

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17

Ding, Jian-Hua, Ting-Chi Wen, Xiao-Min Wu, Saranyaphat Boonmee, Prapassorn D. Eungwanichayapant, and Ling-Sheng Zha. "Species diversity of Tetrigidae (Orthoptera) in Guizhou, China with description of two new species." Journal of Natural History 51, no. 13-14 (2017): 741–60. https://doi.org/10.1080/00222933.2017.1293749.

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Ding, Jian-Hua, Wen, Ting-Chi, Wu, Xiao-Min, Boonmee, Saranyaphat, Eungwanichayapant, Prapassorn D., Zha, Ling-Sheng (2017): Species diversity of Tetrigidae (Orthoptera) in Guizhou, China with description of two new species. Journal of Natural History (J. Nat. Hist.) 51 (13-14): 741-760, DOI: 10.1080/00222933.2017.1293749, URL: http://dx.doi.org/10.1080/00222933.2017.1293749

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18

Wen, Ting-Chi, Yuan-Pin Xiao, Yan-Feng Han, et al. "Multigene phylogeny and morphology reveal that the Chinese medicinal mushroom 'Cordyceps gunnii' is Metacordyceps neogunnii sp. nov." Phytotaxa 302, no. 1 (2017): 27–39. https://doi.org/10.11646/phytotaxa.302.1.2.

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Wen, Ting-Chi, Xiao, Yuan-Pin, Han, Yan-Feng, Huang, Shi-Ke, Zha, Ling-Sheng, Hyde, Kevin D., Kang, Ji-Chuan (2017): Multigene phylogeny and morphology reveal that the Chinese medicinal mushroom 'Cordyceps gunnii' is Metacordyceps neogunnii sp. nov. Phytotaxa 302 (1): 27-39, DOI: 10.11646/phytotaxa.302.1.2, URL: http://dx.doi.org/10.11646/phytotaxa.302.1.2

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19

Xin, Fei-Yi, Xiao-Tian Zhong, Wen-Chi Guo, Yi-Feng Zhang, Zhi-Hao Qi, and Song-Qing Wu. "A taxonomic note on Chinese species of the Neolucanus fuscus group with the description of a new species (Coleoptera: Lucanidae: Lucaninae)." Zootaxa 5570, no. 2 (2025): 344–60. https://doi.org/10.11646/zootaxa.5570.2.6.

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Xin, Fei-Yi, Zhong, Xiao-Tian, Guo, Wen-Chi, Zhang, Yi-Feng, Qi, Zhi-Hao, Wu, Song-Qing (2025): A taxonomic note on Chinese species of the Neolucanus fuscus group with the description of a new species (Coleoptera: Lucanidae: Lucaninae). Zootaxa 5570 (2): 344-360, DOI: 10.11646/zootaxa.5570.2.6, URL: https://doi.org/10.11646/zootaxa.5570.2.6

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Zhao, Wen-Yu, Zhi-Lin Luan, Cheng-Peng Sun, et al. "Metabolites isolated from the human intestinal fungus Penicillium oxalicum SL2 and their agonistic effects on PXR and FXR." Phytochemistry 193 (January 31, 2022): 1–11. https://doi.org/10.1016/j.phytochem.2021.112974.

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Zhao, Wen-Yu, Luan, Zhi-Lin, Sun, Cheng-Peng, Zhang, Bao-Jing, Jin, Ling-Ling, Deng, Sa, Zhang, Hou-Li, Yu, Zhen-Long, Wang, Chao, Ma, Xiao-Chi (2022): Metabolites isolated from the human intestinal fungus Penicillium oxalicum SL2 and their agonistic effects on PXR and FXR. Phytochemistry (112974) 193: 1-11, DOI: 10.1016/j.phytochem.2021.112974, URL: http://dx.doi.org/10.1016/j.phytochem.2021.112974

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Nuraliev, Maxim S., Hironori Toyama, Chi-Ming Hu, et al. "Three new national records from Kon Chu Rang Nature Reserve, Vietnam: Euphorbia bokorensis, Glochidion geoffrayi and Lysimachia nutantiflora." Phytotaxa 574, no. 1 (2022): 73–82. https://doi.org/10.11646/phytotaxa.574.1.4.

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Nuraliev, Maxim S., Toyama, Hironori, Hu, Chi-Ming, Luo, Shi-Xiao, Lyskov, Dmitry F., Kuznetsov, Andrey N., Kuznetsova, Svetlana P., Quang, Bui Hong, Binh, Tran Duc, Hoan, Duong Thi (2022): Three new national records from Kon Chu Rang Nature Reserve, Vietnam: Euphorbia bokorensis, Glochidion geoffrayi and Lysimachia nutantiflora. Phytotaxa 574 (1): 73-82, DOI: 10.11646/phytotaxa.574.1.4, URL: http://dx.doi.org/10.11646/phytotaxa.574.1.4

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22

Wang, Jian, Zhao-Chi Zeng, Zhi-Tong Lyu, et al. "Description of three new Boulenophrys species from eastern Guangdong, China, emphasizing the urgency of ecological conservation in this region (Anura, Megophryidae)." Zootaxa 5099, no. 1 (2022): 91–119. https://doi.org/10.11646/zootaxa.5099.1.4.

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Wang, Jian, Zeng, Zhao-Chi, Lyu, Zhi-Tong, Qi, Shuo, Liu, Zu-Yao, Chen, Hong-Hui, Lu, Yu-Hong, Xiao, Hui-Wen, Lin, Can-Rong, Chen, Kai, Wang, Ying-Yong (2022): Description of three new Boulenophrys species from eastern Guangdong, China, emphasizing the urgency of ecological conservation in this region (Anura, Megophryidae). Zootaxa 5099 (1): 91-119, DOI: 10.11646/zootaxa.5099.1.4

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23

Le-Hoang, Phuong Viet, Yen Truong Thi Ho, Danh Xuan Luu, and Truc Thanh Thi Le. "Determinants of customer's apartment purchase intention: is the location dominant?" Independent Journal of Management & Production 11, no. 4 (2020): 1303. http://dx.doi.org/10.14807/ijmp.v11i4.1100.

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The purpose of this research is to identify and measure the factors affecting the intention to buy apartments of customers in Ho Chi Minh City, Vietnam. The survey carried out with the participation of 200 customers. The authors explore five factors which affect customer's apartment purchase intention include location, features, brand, finance, and subjective norm. The result from Exploratory Factor Analysis (EFA) shows that location, features, finance, and subjective norm have a significant effect on the intention to buy customers' apartments. In which, location in Ho Chi Minh City context is the most influential factor, so, it strongly confirm the research of Adair et al. (1996), Clark et al. (2006), Daly et al. (2003), Kaynak and Stevenson (2007), Opoku and AbdulMuhmin (2010), Sengul et al. (2010), Tu and Goldfinch (1996), Xiao and Tan (2007) and Wang and Li (2006). The study also proposes some recommendations to increase the attractiveness of the apartment. What is more, developers, marketers, real estate policymakers can use the results of this research to understand the needs of customers better and satisfy customers.

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Shek, Daniel T. L., Lu Yu, and Xiao Fu. "Confucian virtues and Chinese adolescent development: a conceptual review." International Journal of Adolescent Medicine and Health 25, no. 4 (2013): 335–44. http://dx.doi.org/10.1515/ijamh-2013-0031.

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Abstract Despite the fact that different Chinese communities have already undergone industrialization and urbanization, Confucian virtues are still regarded as developmental ideals in Chinese culture. Unfortunately, while Confucian virtues are commonly discussed under Chinese philosophies, they are rarely examined in the context of developmental research. In this paper, several key Confucian virtues are discussed, including loyalty (“zhong”), filial piety (“xiao”), benevolence (“ren”), affection (“ai”), trustworthiness (“xin”), righteousness (“yi”), harmony (“he”), peace (“ping”), propriety (“li”), wisdom (“zhi”), integrity (“lian”) and shame (“chi”). These Chinese traditional virtues are also linked to the concepts of character strengths and positive youth development constructs highlighted in Western culture. It is argued that Confucian virtues provide an indigenous conceptual framework to understand character strengths and positive youth development in Chinese culture. Furthermore, when service leadership is considered in Chinese contexts, these virtues should be regarded as important cornerstones.

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Wang, Jia-Peng, Yan Shu, Sheng-Qi Zhang, et al. "Polyketides with antimicrobial activities from Penicillium canescens DJJ-1." Phytochemistry 206 (February 28, 2023): 1–7. https://doi.org/10.1016/j.phytochem.2022.113554.

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Wang, Jia-Peng, Shu, Yan, Zhang, Sheng-Qi, Yao, Lin-Lin, Li, Bing-Xian, Zhu, Li, Zhang, Xiao, Xiao, Huai, Cai, Le, Ding, Zhong-Tao (2023): Polyketides with antimicrobial activities from Penicillium canescens DJJ-1. Phytochemistry (113554) 206: 1-7, DOI: 10.1016/j.phytochem.2022.113554, URL: http://dx.doi.org/10.1016/j.phytochem.2022.113554

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Tseng, Sung-Hui, Ting-Yi Chien, Jiun-Rong Chen, I.-Hsin Lin, and Ching-Chiung Wang. "Hypolipidemic Effects of Three Purgative Decoctions." Evidence-Based Complementary and Alternative Medicine 2011 (2011): 1–10. http://dx.doi.org/10.1093/ecam/nep178.

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In traditional Chinese medicine (TCM), purgation is indicated when a person suffers an illness due to the accumulation of evil internal heat. Obese individuals with a large belly, red face, thick and yellow tongue fur, constipation, and avoidance of heat are thought accumulates of evil internal heat, and they are also treated with purgatives such asTa-Cheng-Chi-Tang(TCCT),Xiao-Chen-Chi-Tang(XCCT), andTiao-Wei-Chen-Chi-Tang(TWCCT) by TCM doctors. In previous studies, our group found that TCCT has potent anti-inflammatory activity, and that XCCT is an effective antioxidant. Since rhubarb is the principle herb in these three prescriptions, we will first present a thorough review of the literature on the demonstrated effect (or lack of effect) of rhubarb and rhubarb-containing polyherbal preparations on lipid and weight control. We will then continue our research with an investigation of the anti-obesity and lipid-lowering effect of TCCT, XCCT, TWCCT, and rhubarb extracts using two animal models. TWCCT lowered the serum triglyceride concentration as much as fenofibrate in Triton WR-1339-treated mice. Daily supplementation with XCCT and TWCCT significantly attenuated the high-fat-diet-induced hypercholesterolemia in rats. In addition, TWCCT also significantly lowered the high-fat-diet-induced hypertriglycemia. Although feeding high-fat diet rats with these extracts did not cause loose stools or diarrhea or other deleterious effects on renal or hepatic function. None of these extracts lowered the body weight of rats fed on high-fat diet. In conclusion, the results suggest that XCCT and TWCCT might exert beneficial effects in the treatment of hyperlipidemia.

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Ding, Xiao, Charng-Sheng Tsai, Mei-Hsuan Tsai, et al. "Abstract 5731: BGB-C354, a novel B7H3 ADC with high DAR stability and strong bystander effect, demonstrates robust antitumor activity in preclinical models." Cancer Research 85, no. 8_Supplement_1 (2025): 5731. https://doi.org/10.1158/1538-7445.am2025-5731.

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Abstract B7H3 is a type I transmembrane protein belonging to the B7 immunoregulatory family. B7H3 is overexpressed on a wide range of solid tumors such as lung cancers, gastrointestinal cancers and gynecological cancers, but its expression is absent or low in normal tissues, making it an attractive target for anticancer therapies. BGB-C354 is a B7-H3-targeting antibody-drug conjugate (ADC) composed of a humanized anti-B7-H3 monoclonal antibody conjugated via a cleavable linker to a novel TOP1i payload, and the drug to antibody ratio (DAR) is approximately 8. Utilizing a stable ring-open conjugator, BGB-C354 demonstrated improved ADC stability and sustained high DAR in vivo, which may enable more efficient payload delivery to B7H3-expressing tumors. In nonclinical pharmacological studies, BGB-C354 exhibited strong target binding activity, high target-dependent internalization, and potent cytotoxicity toward B7H3-expressing tumor cells. In addition, BGB-C354 demonstrated strong bystander killing effect in the presence of B7H3-expressing cell lines to potentially overcome the tumor heterogeneity. Notably, robust anti-tumor activity was observed in a panel of cell-derived xenograft (CDX) models with varying levels of B7-H3 expression, as well as in patient-derived xenograft (PDX) models. Consistent with its mechanism of action, DNA damage and apoptosis biomarker changes were induced by BGB-C354 in a dose-dependent manner after single dosing in preclinical models. Recently, a phase I study of BGB-C354 has been initiated to investigate its potential safety and preliminary efficacy in patients with B7H3-expressing advanced solid tumors (NCT06422520). Citation Format: Xiao Ding, Charng-Sheng Tsai, Mei-Hsuan Tsai, Maggie Tang, Liu Xue, Chi Guan, Meiling Tan, Yiren Xiao, Yuanyuan Xie, Kunpeng Lyu, Xiaotong Chen, Wenhao Li, Qi Liu, Yun Chen, Jie Pan, Wenjin Yao, Yang Lyu, Kaiying Jia, Chang Song, Weiwei Song, Ce Wang, Fan Wang, Zhitao Wan, Mingming Guo, Beibei Jiang, Xiaomin Song, Wei Jin, Qiansheng Ren, Yu Shen, Zhirong Shen. BGB-C354, a novel B7H3 ADC with high DAR stability and strong bystander effect, demonstrates robust antitumor activity in preclinical models [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2025; Part 1 (Regular Abstracts); 2025 Apr 25-30; Chicago, IL. Philadelphia (PA): AACR; Cancer Res 2025;85(8_Suppl_1):Abstract nr 5731.

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Yu, Sheng-Xiang, Magnus Lidén, Bao-Cai Han, and Xiao-Xia Zhang. "Impatiens lixianensis, a new species of Balsaminaceae from Sichuan, China." Phytotaxa 115, no. 1 (2013): 25–30. https://doi.org/10.11646/phytotaxa.115.1.3.

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Yu, Sheng-Xiang, Lidén, Magnus, Han, Bao-Cai, Zhang, Xiao-Xia (2013): Impatiens lixianensis, a new species of Balsaminaceae from Sichuan, China. Phytotaxa 115 (1): 25-30, DOI: 10.11646/phytotaxa.115.1.3, URL: http://dx.doi.org/10.11646/phytotaxa.115.1.3

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Yeh, Ming-Hsien, Hung-Pin Chiu, Mei-Chun Wu, et al. "Integrated Chinese Herbal Medicine and Western Medicine on the Survival in Patients with Colorectal Cancer: A Retrospective Study of Medical Records." Evidence-Based Complementary and Alternative Medicine 2020 (January 13, 2020): 1–10. http://dx.doi.org/10.1155/2020/4561040.

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Recent studies suggested that Traditional Chinese Medicine could play a beneficial role in conventional cancer treatment. The aim of this retrospective cohort study was to investigate the effect of Chinese herbal medicine (CHM) combined with Western medicine on the survival of patients with colorectal cancer. A retrospective cohort study was conducted on patients with newly diagnosed colorectal cancer identified from the Dalin Tzu Chi Hospital Cancer Registry Database in 2004–2014. Combining with the medical records of the study hospital, patients were classified into CHM users and CHM nonusers. Kaplan–Meier analyses and Cox proportional hazards regression analyses were used to investigate the survival between CHM users and CHM nonusers. A total of 535 patients with colorectal cancer were included in the study with 147 of them were CHM users. The log-rank test for Kaplan–Meier survival curve revealed a statistically significant difference between the survival of CHM users and CHM nonusers (P=0.006). Results from multivariate Cox regression analysis showed that CHM use was significantly associated with better survival (adjusted hazard ratio = 0.54, 95% CI = 0.38 to 0.77). In addition, the CHM formulae Jia Wei Xiao Yao San, Zhi Bah Di Huang Wan, Ping Wei San, and Qui Pi Tang were significantly associated with better survival. In conclusion, findings from this retrospective cohort study indicated that integrated CHM and Western medicine could improve survival in patients with colorectal cancer. Additional research on integrating TCM with Western medicine to improve cancer survival is warranted.

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Chow, Hei Ching, Tsz Him So, Horace Cheuk Wai Choi, and Ka On Lam. "Literature Review of Traditional Chinese Medicine Herbs–Induced Liver Injury From an Oncological Perspective With RUCAM." Integrative Cancer Therapies 18 (January 2019): 153473541986947. http://dx.doi.org/10.1177/1534735419869479.

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Traditional Chinese medicine (TCM) herbs are commonly regarded to be safe with minimal toxicities in Chinese communities. Cancer patients who are receiving Western oncology therapy often concurrently take TCM herbs for anticancer and symptom relief purposes. We performed a literature review for current evidence on TCM herb–induced liver injury from an oncological perspective. A literature search on PubMed was performed to identify publications regarding TCM herbs and concoctions with hepatoprotective or hepatotoxic properties. Lists of commonly used herbs and their causality levels were compiled. In view of the wide range of evidence available, cases assessed by the well-established RUCAM (Roussel Uclaf Causality Assessment Method) algorithm were categorized as the highest level of evidence. More than one case of TCM herb–induced liver injury was confirmed by RUCAM in the following herbs and concoctions: Lu Cha ( Camellia sinensis), Bai Xian Pi ( Dictamnus dasycarpus), Tu San Qi ( Gynura segetum), Jin Bu Huan ( Lycopodium serratum), He Shou Wu ( Polygoni multiflora), Ge Gen ( Pueraria lobata), Dan Lu Tong Du tablet, Shou Wu Pian, Xiao Chai Hu Tang, Xiao Yin pill, and Yang Xue Sheng Fa capsule. Finally, TCM with anticancer or symptom relief uses were discussed in detail with regard to their hepatotoxic or hepatoprotective properties.

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Gao, Yue, Chun-Jie Liu, Hua-Yi Li, et al. "Abstract LB168: Platelet RNA signature enables early and accurate detection of ovarian cancer: An intercontinental, biomarker identification study." Cancer Research 82, no. 12_Supplement (2022): LB168. http://dx.doi.org/10.1158/1538-7445.am2022-lb168.

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Abstract Background: Morpho-physiological alternations of platelets provided a rationale to harness RNA sequencing of tumor-educated platelets (TEPs) for preoperative diagnosis of cancer. Timely, accurate, and non-invasive detection of ovarian cancer in women with adnexal masses presents a significant clinical challenge. Patients and Methods: This intercontinental, hospital-based, diagnostic study included 761 treatment-naïve inpatients with histologically confirmed adnexal masses and 167 healthy controls from nine medical centers (China, n=3; Netherlands, n=5; Poland, n=1) between September 2016 and May 2019. The main outcomes were the performance of TEPs and their combination with CA125 in two Chinese (VC1 and VC2) and the European (VC3) validation cohorts collectively and independently. Exploratory outcome was the value of TEPs in public pan-cancer platelet transcriptome datasets. Results: The AUCs for TEPs in the combined validation cohort, VC1, VC2, and VC3 were 0.918 (95% CI 0.889-0.948), 0.923 (0.855-0.990), 0.918 (0.872-0.963), and 0.887 (0.813-0.960), respectively. Combination of TEPs and CA125 demonstrated an AUC of 0.922 (0.889-0.955) in the combined validation cohort; 0.955 (0.912-0.997) in VC1; 0.939 (0.901-0.977) in VC2; 0.917 (0.824-1.000) in VC3. For subgroup analysis, TEPs exhibited an AUC of 0.858, 0.859, and 0.920 to detect early-stage, borderline, non-epithelial diseases and 0.899 to discriminate ovarian cancer from endometriosis. Analysis of public datasets suggested that TEPs had potential to detect multiple malignancies (Table 1). Conclusions: TEPs had robustness, compatibility, and universality for preoperative diagnosis of ovarian cancer since it withstood validations in populations of different ethnicities, heterogeneous histological subtypes, early-stage ovarian cancer as well as other malignancies. However, these observations warrant prospective validations in a larger population before clinical utilities. Table 1. Performance for TEPs in public pan-cancer datasets. Disease n Healthy Control AUC, area under the curve (95% CI) Women NSCLC (non-small-cell lung cancer) 126 77 0.758 (0.691-0.825) Breast cancer 38 77 0.817 (0.726-0.909) Colorectal cancer 18 77 0.973 (0.945-1.000) Pancreatic cancer 16 77 0.993 (0.981-1.000) Glioblastoma 10 77 0.923 (0.831-1.000) Men NSCLC 119 82 0.746 (0.677-0.815) Colorectal cancer 25 82 0.933 (0.884-0.982) Pancreatic cancer 22 82 0.993 (0.984-1.000) Glioblastoma 19 82 0.981 (0.959-1.000) All NSCLC 245 159 0.774 (0.728-0.820) Colorectal cancer 40 159 0.978 (0.961-0.996) Breast cancer 38 159 0.821 (0.736-0.906) Pancreatic cancer 35 159 0.987 (0.974-0.999) Glioblastoma 35 159 0.931 (0.890-0.972) Hepatobiliary carcinomas 14 159 0.991 (0.978-1.000) Citation Format: Yue Gao, Chun-Jie Liu, Hua-Yi Li, Xiao-Ming Xiong, Sjors G.j.g. In ‘t Veld, Gui-Ling Li, Jia-Hao Liu, Guang-Yao Cai, Gui-Yan Xie, Shao-Qing Zeng, Yuan Wu, Jian-Hua Chi, Qiong Zhang, Xiao-Fei Jiao, Lin-Li Shi, Wan-Rong Lu, Wei-Guo Lv, Xing-Sheng Yang, Jurgen M.j. Piek, Cornelis D de Kroon, C.a.r. Lok, Anna Supernat, Sylwia Łapińska-Szumczyk, Anna Łojkowska, Anna J. Żaczek, Jacek Jassem, Bakhos A. Tannous, Nik Sol, Edward Post, Myron G. Best, Bei-Hua Kong, Xing Xie, Ding Ma, Thomas Wurdinger, An-Yuan Guo, Qing-Lei Gao. Platelet RNA signature enables early and accurate detection of ovarian cancer: An intercontinental, biomarker identification study [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr LB168.

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Zhou, Xinyu, Alexander White, Tingbo Guo, et al. "Abstract 4274: Functional dissection of complex tissue microenvironment using spatial transcriptomics data." Cancer Research 83, no. 7_Supplement (2023): 4274. http://dx.doi.org/10.1158/1538-7445.am2023-4274.

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Abstract Spatial transcriptomics (ST) data holds enormous potential to provide new perspectives for biologists seeking to understand the tumor tissue microenvironments. Cells in the same microenvironment are always exposed to biochemical conditions displacing specific spatial patterns. To truly dismantle the tissue microenvironment heterogeneity as well as cells’ diverse responses to the variable microenvironment, we rely on spatial information to dissect the tissue into different functional regions, which are spatially dependent and biologically meaningful. We have developed a statistical method, smooth Low Rank approximation and Clustering (smoothLRC) to model the spatial transcriptomic data as its low-rank approximation with spatial smoothness. smoothLRC accomplishes this by extracting the latent low-rank structure of the expression profiles. We present a regularized maximum likelihood estimator approximating the noisy observed expression matrix. This estimator incorporates spatial information and addresses expression dropout. It uses a low-rank Poisson distribution to account for the noise that plagues ST-based gene expression data with severe dropout events and a spatial smoothness penalty to encourage neighboring cells to fall into the same functional region. A dropout is an event where genes expressed in a given cell or region are incorrectly measured as unexpressed. SmoothLRC has the following key features: 1) it is a statistically rigorous method; 2) the spatially smooth low-rank subspace could enable meaningful functional dissection, which is an unprecedented capability; 3) the low-rank structures could be used to recover the original expression, saving many expression values that are not captured. Citation Format: Xinyu Zhou, Alexander White, Tingbo Guo, Pengtao Dang, Yuhui Wei, Xiao Wang, Kaman So, Chi Zhang, Sha Cao. Functional dissection of complex tissue microenvironment using spatial transcriptomics data. [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2023; Part 1 (Regular and Invited Abstracts); 2023 Apr 14-19; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2023;83(7_Suppl):Abstract nr 4274.

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Zhou, Xian-Li, Shan-Bin Li, Meng-Qi Yan, et al. "Bioactive dammarane triterpenoid saponins from the leaves of Cyclocarya paliurus." Phytochemistry 183 (March 31, 2021): 1–11. https://doi.org/10.1016/j.phytochem.2020.112618.

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Zhou, Xian-Li, Li, Shan-Bin, Yan, Meng-Qi, Luo, Qin, Wang, Li-Sheng, Shen, Ling-Li, Liao, Mei-Lian, Lu, Cai-Hua, Liu, Xia-Yan, Liang, Cheng-Qin (2021): Bioactive dammarane triterpenoid saponins from the leaves of Cyclocarya paliurus. Phytochemistry (112618) 183: 1-11, DOI: 10.1016/j.phytochem.2020.112618, URL: http://dx.doi.org/10.1016/j.phytochem.2020.112618

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Li, Jin-Feng, Kai-Long Ji, Peng Sun, et al. "Structurally diverse steroids with nitric oxide inhibitory activities from Aglaia lawii leaves." Phytochemistry 183 (March 31, 2021): 1–8. https://doi.org/10.1016/j.phytochem.2020.112651.

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Li, Jin-Feng, Ji, Kai-Long, Sun, Peng, Cai, Qiang, Zheng, Xiao-Ling, Xiao, Yi-Dian, Cao, Dong-Hua, Xiao, Chun-Fen, Zhang, Zong-Yi, Li, Xiao-Nian, Hu, Hua-Bin, Yu, Zhi-Yong, Xu, You-Kai (2021): Structurally diverse steroids with nitric oxide inhibitory activities from Aglaia lawii leaves. Phytochemistry (112651) 183: 1-8, DOI: 10.1016/j.phytochem.2020.112651, URL: http://dx.doi.org/10.1016/j.phytochem.2020.112651

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Wang, Yi, Li Li, Yan-Mei Cheng, and Sheng-Liang Zhu. "Xiao Chai Hu Tang for Liver Diseases:A Literature Review." World Journal of Traditional Chinese Medicine 3 (2017): 1–5. http://dx.doi.org/10.15806/j.issn.2311-8571.2016.0041.

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IWAI, Takaaki, Tadato TANI, and Shigeru ARICHI. "Evaluation of Xiao-Chai-Hu-Tang prepared by patients." Kampo Medicine 39, no. 3 (1989): 201–5. http://dx.doi.org/10.3937/kampomed.39.201.

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Du, Ting, Min Zeng, Li Chen, Zheng Cao, Hua Cai, and Guangde Yang. "Chemical and absorption signatures of Xiao Chai Hu Tang." Rapid Communications in Mass Spectrometry 32, no. 14 (2018): 1107–25. http://dx.doi.org/10.1002/rcm.8114.

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Volpp, Sophie. "The Chinese Garden as Lyric Enclave: A Generic Study of the Story of the Stone. By Chi Xiao. Michigan Monographs in Chinese Studies, no. 93. Ann Arbor: Center for Chinese Studies Publications, University of Michigan, 2001. xii, 286 pp. $50.00 (cloth)." Journal of Asian Studies 63, no. 4 (2004): 1118–19. http://dx.doi.org/10.1017/s0021911804002682.

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Chen, Jia-Xu, Bo Ji, Zhao-Lin Lu та Li-Sheng Hu. "Effects of Chai Hu (Radix Burpleuri) Containing Formulation on Plasma β-endorphin, Epinephrine and Dopamine in Patients". American Journal of Chinese Medicine 33, № 05 (2005): 737–45. http://dx.doi.org/10.1142/s0192415x05003296.

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Chai Hu (Radix Burpleuri), a major ingredient in many traditional Chinese medicine formulas, such as Xiao Yao Wan, is used in the treatment of liver stagnation and spleen deficiency syndrome (LSSDS). The objectives of this study were to examine the effects of Xiao Yao Wan containing Chai Hu on the changes of plasma indices in patients with LSSDS. Fifty-eight cases of LSSDS were randomly divided into two groups: 41 cases in the experimental group were treated with Xiao Yao Wan containing Chai Hu and 17 cases in the control group were treated with Zhi Bai Di Huang Wan for one consecutive month in a single blind design. Before and after treatment, high performance liquid chromatography (HPLC) was applied to determine the changes of plasma norepinephrine (NE), epinephrine (E) and dopamine (DA). Radioimmunoassay was performed to measure the amount of plasma β-endorphin (β-EP), adrenocorticotropin hormone (ACTH), estradiol (E2) and testosterone (T), and laser nephelometry was also conducted to measure plasma immunoglobulin A (Ig A) and G (Ig G). Compared to baseline levels, plasma β-EP was significantly increased ( p < 0.01), while E and DA were markedly decreased ( p < 0.01) after the administration of Xiao Yao Wan in the experimental group. The other indices did not change. This is the first evidence showing that the effect of Xiao Yao Wan containing Chai Hu on the treatment of patients with LSSDS may be through enhancing plasma β-EP and decreasing E and DA release. We conclude that Xiao Yao Wan containing Chai Hu regulates nervous and endocrine systems and contributes to the improvement of the clinical status of patients with LSSDS.

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Trehan, Rajiv S., Marlaine Soliman, Xin Wang, et al. "Abstract 3970: Impairment of tumor reactive CD8 T cells in liver cancer." Cancer Research 84, no. 6_Supplement (2024): 3970. http://dx.doi.org/10.1158/1538-7445.am2024-3970.

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Abstract Tumor reactive (TR) CD8 T cells in the liver have been studied in the setting of both immunotherapy and cellular therapy with the predominant dogma that these cells have equivalent functionality in the liver as compared to other organ sites. Herein, we detail that TR+ CD8 T cells are functionally impaired in the liver immune microenvironment in mice with liver tumors.TR+ CD8 T cells were studied in BALB/c and C57BL/6 mice injected intrahepatic, intravenous, and subcutaneously with either a colon (CT26) or a melanoma (B16F10) cancer cell line to create intrahepatic, pulmonary and subcutaneous tumors, respectively. Additionally, an ⍺CD8 antibody with IgG control was used to conduct functional studies. Samples were analyzed using flow cytometry and liver weights were measured. A high frequency of TR+ CD8 T cells were found in the liver in mice with intrahepatic tumors. Despite ~70% of CD8 T cells being tumor reactive in intrahepatic tumors, liver tumor growth kinetics were faster than subcutaneous tumors. Higher proportion of the TR+ CD8 T cells were found to be exhausted in the liver tumor by flow cytometry. Functional depletion of the CD8 T cells caused a fivefold higher tumor growth in the subcutaneous model but in contrast had no effect on intrahepatic tumors. In conclusion, despite the high frequency of “killer” tumor reactive T cells in the liver, the growth kinetics of the liver tumors, flow cytometry as well as functional studies demonstrate the impairment of TR+ CD8 T cells in the liver. We aim to dissect the mechanisms mediating intrahepatic TR CD8+ T cell exhaustion in primary liver tumors as well as metastatic models. Additionally, we aim to determine significant costimulatory molecules specific to intrahepatic exhaustion which could lead to better therapeutic models. Citation Format: Rajiv S. Trehan, Marlaine Soliman, Xin Wang, Patrick Huang, Noemi Kedei, Xiao Bin Zhu, Matthias Seifert, Mohamed-Reda Benmebarek, Amran Nur, Firouzeh Korangy, Chi Ma, Tim F. Greten. Impairment of tumor reactive CD8 T cells in liver cancer [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2024; Part 1 (Regular Abstracts); 2024 Apr 5-10; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2024;84(6_Suppl):Abstract nr 3970.

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Zhu, Sheng-Liang, Yi Wang, Li Li, and Yan-Mei Cheng. "Xiao chai hu tang for liver diseases: A literature review." World Journal of Traditional Chinese Medicine 3, no. 3 (2017): 46. http://dx.doi.org/10.4103/wjtcm.wjtcm_4_17.

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Tian, J., L. Liu, S.Y. Xiao, et al. "Tian, J., Liu, L., Xiao, S.Y., Zhu, X.W., Wu, Y.J., Zhou, L., Yin, J., Peng, L., Cai, X.Z., Liu, L.H., Liu, Y.D., & Liu, K.M., (2018) Primulina hengshanensis (Gesneriaceae), a new species from Danxia landform in Hunan, China. Phytotaxa 333 (2): 293-297." Phytotaxa 336, no. 1 (2018): 100. https://doi.org/10.11646/phytotaxa.336.1.9.

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Tian, J., Liu, L., Xiao, S.Y., Zhu, X.W., Wu, Y.J., Zhou, L., Yin, J., Peng, L., Cai, X.Z., Liu, L.H., Liu, Y.D., Liu, K.M. (2018): Tian, J., Liu, L., Xiao, S.Y., Zhu, X.W., Wu, Y.J., Zhou, L., Yin, J., Peng, L., Cai, X.Z., Liu, L.H., Liu, Y.D., & Liu, K.M., (2018) Primulina hengshanensis (Gesneriaceae), a new species from Danxia landform in Hunan, China. Phytotaxa 333 (2): 293-297. Phytotaxa 336 (1): 100-100, DOI: 10.11646/phytotaxa.336.1.9, URL: http://dx.doi.org/10.11646/phytotaxa.336.1.9

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NAKAMURA, Toichiro, Tsuneo TAKAHASHI, Haruhide SHINZAWA, Hitoshi TOGASHI, and Makoto ISHIKAWA. "Effect of Xiao-Chai-Hu-tang on paraquat-induced liver injury." Kanzo 31, no. 11 (1990): 1324–33. http://dx.doi.org/10.2957/kanzo.31.1324.

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Hsu, Li-Ming, Yi-Shin Huang, Shyh-Haw Tsay, Full-Young Chang, and Shou-Dong Lee. "Acute Hepatitis Induced by Chinese Hepatoprotective Herb, Xiao-Chai-Hu-Tang." Journal of the Chinese Medical Association 69, no. 2 (2006): 86–88. http://dx.doi.org/10.1016/s1726-4901(09)70119-4.

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Kong, Weikaixin, Weiran Huang, Zhuo Huang, and Zhengwei Xie. "Network Pharmacology Analysis of Anticonvulsant Effect of Xiao Chai Hu Tang." IOP Conference Series: Earth and Environmental Science 545 (July 28, 2020): 012011. http://dx.doi.org/10.1088/1755-1315/545/1/012011.

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Tian, Jing, Lei Liu, Shun-Yong Xiao, et al. "Primulina hengshanensis (Gesneriaceae), a new species from Danxia landform in Hunan, China." Phytotaxa 333, no. 2 (2018): 293–97. https://doi.org/10.11646/phytotaxa.333.2.15.

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Tian, Jing, Liu, Lei, Xiao, Shun-Yong, Zhu, Xiao-Wen, Wu, Yao-Jing, Zhou, Liu, Yin, Juan, Pen, Ling, Cai, Xiu-Zhen, Liu, Lin-Han, Liu, Ying-Ding, Liu, Ke-Ming (2018): Primulina hengshanensis (Gesneriaceae), a new species from Danxia landform in Hunan, China. Phytotaxa 333 (2): 293-297, DOI: 10.11646/phytotaxa.333.2.15, URL: http://dx.doi.org/10.11646/phytotaxa.333.2.15

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Chou, Shu-Huey, Chun-Che Huang, Ching-Heng Lin, Kun-Chang Wu, and Pei-Jung Chiang. "General Use of Chinese Herbal Products among Female Patients with Mastitis in Taiwan." Evidence-Based Complementary and Alternative Medicine 2022 (March 25, 2022): 1–9. http://dx.doi.org/10.1155/2022/3876240.

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Objectives. Little information is available regarding the use of Chinese herbal medicine to treat mastitis. This study evaluated the prescription patterns of Chinese herbal medicine products in women with mastitis in Taiwan. Design. This is a population-based cross-sectional study. Setting. 8,531 women aged 20–49 years, who received a diagnosis of mastitis between 2004 and 2013, were identified from the Longitudinal Health Insurance Database in Taiwan. We collected data on demographic characteristics, including age, monthly insurance premium, and urbanization level. The ten most Chinese herbal medicines prescribed for mastitis were assessed, including frequency, percentage, average daily dose, and average duration of prescription. Main outcome measures. We analysed the ten most single Chinese herbs and Chinese herbal formulae prescribed for mastitis. Results. Overall, 437 (5.1%) women received Chinese herbal medicine to treat mastitis. Mai Men Dong (Ophiopogon japonicus (Thunb.) Ker Gawl.; 22.3%), Pu Gong Yin (Taraxacum mongolicum Hand.-Mazz.; 7.8%), and Wang Bu Liu Xing (Vaccaria hispanica (Mill.) Rauschert; 3.5%) were three of the most commonly prescribed single Chinese herbs for mastitis. Xian-Fang-Huo-Ming-Yin (18.2%), Jia-Wei-Xiao-Yao-San (9.1%), and Chai-Hu-Shu-Gan-San (8.4%) were three of the most commonly prescribed Chinese herbal formulae. Conclusion. Xian-Fang-Huo-Ming-Yin can clear heat, detoxify body, alleviate swelling, activate blood, and relieve pain. It was the most frequently prescribed Chinese herbal formula in patients with mastitis.

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Yamamoto, S., T. Arai, H. Tsutsui, Y. Mizoguchi, S. Morisawa, and M. Aburada. "Effects of Xiao-Chai-Hu-Tang on the antibody response in vitro." International Journal of Immunopharmacology 7, no. 3 (1985): 359. http://dx.doi.org/10.1016/0192-0561(85)90337-6.

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Wopperer, Samuel, Kamal Baig, Joseph Jennings, and Alexander Lalos. "A Rare Case of Xiao Chai Hu Tang Induced Acute Liver Failure." American Journal of Gastroenterology 113, Supplement (2018): S1243—S1244. http://dx.doi.org/10.14309/00000434-201810001-02176.

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Sanae, Fujiko, Ken-ichi Miyamoto, Hiroyuki Sawanishi, et al. "Hypoglycaemic Effects ofShokatsu-Cha(Xiao-Ke-Ca) in Streptozotocin-induced Diabetes Mellitus." Phytotherapy Research 10, no. 2 (1996): 127–30. http://dx.doi.org/10.1002/(sici)1099-1573(199603)10:2<127::aid-ptr784>3.0.co;2-q.

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