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1

Labudová, M., J. Beňačka, and I. Zambojová. "Výskyt a závažnosť erektilnej dysfunkcie u pacientov s hypertenziou / Incidence and severity of erectile dysfunction in patients with hypertension." Cardiology letters 30, no. 01 (2021): 37–41. http://dx.doi.org/10.4149/cardiol_2021_1_7.

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2

Horňáková, Lenka, and Monika Ďurfinová. "Potenciálne nové markery predikcie komplikácii a priebehu ochorenia Covid-19 / New potential markers for predicting the complications and course of Covid-19." Laboratórna Diagnostika XXVI, no. 2/2021 (2021): 31–40. https://doi.org/10.5281/zenodo.5761740.

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<strong>S&Uacute;HRN</strong> Bilancia ľudsk&yacute;ch životov straten&yacute;ch počas pand&eacute;mie COVID-19 vo svete je značn&aacute;, keďže k&nbsp;2.11. 2021 prekročil celosvetovo počet &uacute;mrt&iacute; 5 mili&oacute;nov. K tomu treba e&scaron;te pripoč&iacute;tať n&aacute;klady na zv&yacute;&scaron;en&uacute; mieru chudoby, naru&scaron;enie pracovn&eacute;ho a s&uacute;kromn&eacute;ho života, rast&uacute;ce soci&aacute;lne nepokoje, &nbsp;potrebu rie&scaron;iť n&aacute;rast psychologick&yacute;ch probl&eacute;mov det&iacute; aj dospel&yacute;ch,&nbsp; prevenciu a&nbsp;liečbu z&aacute;važn&yacute;ch diagn&oacute;z (onkologick&eacute;, kardiovaskul&aacute;rne, metabolick&eacute; a in&eacute;), ktor&eacute; boli kv&ocirc;li pand&eacute;mii ods&uacute;van&eacute;. Včasn&aacute; a&nbsp;presn&aacute; laborat&oacute;rna diagnostika ochorenia COVID-19 zohr&aacute;va v&yacute;znamn&uacute; &uacute;lohu pri spomaľovan&iacute; a&nbsp;kontrolovan&iacute; pand&eacute;mie. Po potvrden&iacute; pr&iacute;tomnosti SARS-CoV-2 v&iacute;rusu v organizme sa u symptomatick&yacute;ch pacientov sleduj&uacute; viacer&eacute; hematologick&eacute; a z&aacute;palov&eacute; markery poukazuj&uacute;ce na z&aacute;važnosť klinick&eacute;ho stavu pacienta. Neust&aacute;le sa v&scaron;ak vyhľad&aacute;vaj&uacute; a testuj&uacute; nov&eacute; vhodn&eacute; biochemick&eacute; markery hlavne na predikciu priebehu ochorenia s cieľom maxim&aacute;lne zn&iacute;žiť mortalitu sp&ocirc;soben&uacute; touto v&iacute;rusovou infekciou, ale z&aacute;roveň aj posilniť glob&aacute;lnu pripravenosť a schopnosť lep&scaron;ie reagovať na podobn&eacute; situ&aacute;cie v bud&uacute;cnosti. <strong>ABSTRACT</strong> The balance of human lives lost during the COVID-19 pandemic is significant, as more than 5 million people have died (by November 2021), in addition to the costs of increased poverty, disruption of work and private life and growing social unrest. Early and accurate laboratory diagnosis of Covid-19 plays an important role in slowing down and controlling the pandemics. After confirmation of the presence of the SARS-CoV-2 virus in the human body, there are several hematological and inflammation markers monitored in symptomatologic patients, which can indicate severity of the clinical state of the patient. However, new suitable biochemical markers are constantly being sought and tested, mainly to predict the course of the disease in order to minimize mortality caused by this viral infection, but also to strengthen global preparedness and ability to respond better to similar situations in the future.
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3

Ehler, Edvard, Ivana Štětkářová, and Karol Čurila. "Severity of cardiac involvement in Emery­‑Dreifuss muscular dystrophy." Neurologie pro praxi 25, no. 5 (2024): 353–56. http://dx.doi.org/10.36290/neu.2024.033.

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4

Rob, Filip, and Jana Hercogová. "Assessment of atopic eczema severity with EASI." Dermatologie pro praxi 14, no. 1 (2020): 6–8. http://dx.doi.org/10.36290/der.2020.001.

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5

Zajíček, Robert, Ivana Grosová, and Hubert Šuca. "Factors severity of burn injury in childhood." Pediatrie pro praxi 17, no. 4 (2016): 240–43. http://dx.doi.org/10.36290/ped.2016.055.

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6

Franková, Soňa, and Jan Šperl. "Non-invasive methods in the assessment of portal hypertension severity." Gastroenterologie a hepatologie 75, no. 2 (2021): 125–33. http://dx.doi.org/10.48095/ccgh2021125.

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Portal hypertension represents a wide spectrum of complications of chronic liver diseases and may present by ascites, oesophageal varices, splenomegaly, hypersplenism, hepatorenal and hepatopulmonary syndrome or portopulmonary hypertension. Portal hypertension and its severity predicts the patient‘s prognosis: as an invasive technique, the portosystemic gradient (HPVG – hepatic venous pressure gradient) measurement by hepatic veins catheterisation has remained the gold standard of its assessment. A reliable, non-invasive method to assess the severity of portal hypertension is of paramount importance; the patients with clinically significant portal hypertension have a high risk of variceal bleeding and higher mortality. Recently, non-invasive methods enabling the assessment of liver stiffness have been introduced into clinical practice in hepatology. Not only may these methods substitute for liver biopsy, but they may also be used to assess the degree of liver fibrosis and predict the severity of portal hypertension. Nowadays, we can use the quantitative elastography (transient elastography, point shear-wave elastrography, 2D-shear-wave elastography) or magnetic resonance imaging. We may also assess the severity of portal hypertension based on the non-invasive markers of liver fibrosis (i.e. ELF test) or estimate clinically signifi cant portal hypertension using composite scores (LSPS – liver spleen stiff ness score), based on liver stiffness value, spleen diameter and platelet count. Spleen stiffness measurement is a new method that needs further prospective studies. The review describes current possibilities of the non-invasive assessment of portal hypertension and its severity.
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7

Džupa, V., R. Grill, F. Fridrich, M. Krbec, J. Skála-Rosenbaum, and V. Báča. "Pelvic Injuries and Acetabular Fractures: Differences in their Severity." Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca 80, no. 1 (2013): 60–63. http://dx.doi.org/10.55095/achot2013/009.

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8

Solecká, Šárka, Jan Betka, Karel Matler, and Hana Tomášková. "The importance of screening questionnaires in detecting the severity of obstructive sleep apnea." Otorinolaryngologie a foniatrie 70, no. 2 (2021): 75–81. http://dx.doi.org/10.48095/ccorl202175.

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ntroduction: The aim of this study is to compare the importance of screening questionnaires and risk factors in detecting the severity of obstructive sleep apnea (OSA). Methods: The study included 47 patients with suspected OSA. The patients completed 5 screening questionnaires – the Epworth Sleepiness Scale (ESS), the STOP BANG questionnaire, the STOP questionnaire, the Berlin questionnaire (BQ) and the Pittsburgh Sleep Quality Index (PSQI). Subsequently, they were examined by the limited polygraphy. AHI (number of apneas/ hypopneas per 1 hour), t90 desaturation (percentage of sleep time spent in desaturations below 90%) and ODI (number of desaturations ≥ 3% within 1 hour) were compared with questionnaire scores and selected risk factors for OSA (BMI, male gender, hypertension, age, neck circumference, abdominal circumference and abdominal/ hip circumference ratio). Results: The achieved score of any of the monitored questionnaires does not correlate with the value of AHI. BQ, STOP and STOP BANG questionnaires have the relatively highest sensitivity for OSA detection, while the sensitivity of PSQI and ESS is low. The correlation of the ESS, STOP BANG and BQ scores with the t90 desaturation, as well as the ESS and STOP BANG scores with the ODI is statistically signifi cant. The relationship of any of the selected risk factors with the AHI value has not been demonstrated. Desaturation values of t90 and ODI correlated best with BMI, neck circumference and abdominal/ hip circumference ratio. Conclusion: None of the monitored questionnaires is suitable for determining the severity of OSA, it is always necessary to perform a polygraphic or polysomnographic examination of sleep. BQ and STOPBANG are relatively most suitable for OSA screening. They both have high sensitivity and, at the same time, their score correlates with the value of nocturnal hypoxemia. Parameters measuring nocturnal hypoxemia (t90 desaturation, ODI) correlate better with risk factors than AHI. The most important parameters associated with hypoxemia are BMI, neck circumference and abdominal/ hip circumference ratio and it is appropriate to include them in the screening for OSA. Keywords: obstructive sleep apnea – Berlin questionnaire – STOP-Bang questionnaire – STOP questionnaire – Epworth sleepiness scale – Pittsburgh Sleep Quality Index
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9

Kaiser, R., P. Waldauf, and P. Haninec. "Scapular Fracture Related to Polytrauma Severity in Patients with Serious Brachial Plexus Palsy." Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca 80, no. 4 (2013): 284–86. http://dx.doi.org/10.55095/achot2013/047.

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10

Zjarová, Zuzana, and Viktória Kevická. "The Impact of Aphasia Severity on Spontaneous Speech: Why Is It Important to Assess Coherence and Informativeness?" Listy klinické logopedie 9, no. 1 (2025): 19–24. https://doi.org/10.36833/lkl.2025.006.

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11

Ercan, Suleyman, Gokhan Altunbas, Dursun Cayan Akkoyun, Vedat Davutoglu, and Hayati Deniz. "Association between blood group antigens and rheumatic valve involvement and severity in endemic areas." Cor et Vasa 55, no. 5 (2013): e424-e426. http://dx.doi.org/10.1016/j.crvasa.2013.06.006.

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12

Malina, P., D. Novotný, P. Krumpholcová, I. Tozzi, and V. Procházka. "Possibility of prediction of acute pancreatitis severity by determination of adipokines (adiponectin, FGF-21 and A-FABP) during hospitalization." Klinická biochemie a metabolismus 22, no. 1 (2014): 16–21. https://doi.org/10.61568/kbm.2014.005.

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13

KOTAŠKA, J., L. HANOUSKOVÁ, R. PRŮŠA, T. TRČ, and K. KOTAŠKA. "Concentration of Hyaluronic Acid in Synovial Fluid as an Indicator of Severity and Degree of Impairment in Patients Suffering from Gonarthrosis." Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca 88, no. 2 (2021): 83–86. http://dx.doi.org/10.55095/achot2021/015.

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14

Novotný, D., P. Malina, P. Krumpholcová, I. Tozzi, and V. Procházka. "The acute pancreatitis severity prediction using adiponectin, adipocyte fatty acid binding protein and fibroblast growth factor 21 levels in day 4 after admission." Klinická biochemie a metabolismus 23, no. 1 (2015): 9–16. https://doi.org/10.61568/kbm.2015.003.

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15

Pavlušová, Marie, Roman Miklík, Radim Špaček, et al. "Increased dose of diuretics correlates with severity of heart failure and renal dysfunction and does not lead to reduction of mortality and rehospitalizations due to acute decompensation of heart failure; data from AHEAD registry." Cor et Vasa 60, no. 3 (2018): e215-e223. http://dx.doi.org/10.1016/j.crvasa.2017.09.007.

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