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1

Henao Castañeda, Isabel C., Jaime A. Pereañez, and Lina M. Preciado. "Synthetic Inhibitors of Snake Venom Enzymes: Thioesters Derived from 2-Sulfenyl Ethylacetate." Pharmaceuticals 12, no. 2 (2019): 80. http://dx.doi.org/10.3390/ph12020080.

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Snakebite envenomings are a global public health issue. The therapy based on the administration of animal-derived antivenoms has limited efficacy against the venom-induced local tissue damage, which often leads to permanent disability. Therefore, there is a need to find inhibitors against toxins responsible for local damage. This work aimed to synthesize thioesters derived from 2-sulfenyl ethylacetate and to evaluate the inhibitory effects on two snake venom toxins. Ethyl 2-((4-chlorobenzoyl)thio)acetate (I), Ethyl 2-((3-nitrobenzoyl)thio)acetate (II) and Ethyl 2-((4-nitrobenzoyl)thio)acetate
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2

Liu, Xiao Zhen, Jun Hua Yang, Gang Wang, Ling Ling Song, and Ge Shi Zhuang. "Effect of Preparation Conditions on the Performance of Anodic Aluminum Oxide Films." Applied Mechanics and Materials 164 (April 2012): 223–26. http://dx.doi.org/10.4028/www.scientific.net/amm.164.223.

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Neodymium salt was used as additives in preparing anodic aluminum oxide (AAO) films to improve its performance. AAO films were prepared by anodization method from a 15 vol. % sulphuric acid solution containing neodymium salt. The effects of anodization voltage, anodization temperature and anodization time on microhardness and thickness of AAO films were researched, respectively. The thickness of AAO film increases with the increase of anodization voltage, the microhardness of AAO film decreases with the increase of anodization voltage in 19 V~23 V. The thickness of AAO film increases with the
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3

Arpan, Jadav *. and Sandip Singh. "SYNTHESIS OF NEW PYRIMIDINE DERIVATIVES AS POTENTIAL ANTICANCER AGENT." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 04 (2018): 2990–95. https://doi.org/10.5281/zenodo.1231060.

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We have tried to synthesize a series of 5 derivatives of Pyrimidine. Synthesis was carried out according to reactions shown in Reaction Scheme. At first, 4th position of 2,4 dichloropyrimidne was substituted by Anthranilic acid to form Synthesis of 2-(2- chloropyrimidin-4-ylamino)benzoic acid 1[C]. 5amino-1,3,4-thiadiazole 2[B] was prepared using Synthesis of 2-(2-chloropyrimidin-4ylamino)benzoic acid 1[C] and Thiosemicarbazide as starting material. Further confirmation was carried out by IR which showed the presence of amino (-NH2) band ~3422.80 cm-1, 1H NMR spectra which revealed all the cor
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4

Lakhlani, P. P., D. M. Lovinger, and L. E. Limbird. "Genetic evidence for involvement of multiple effector systems in alpha 2A-adrenergic receptor inhibition of stimulus-secretion coupling." Molecular Pharmacology 50, no. 1 (1996): 96–103. https://doi.org/10.1016/s0026-895x(25)09172-2.

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5

Žiak, Peter, Juraj Halička, Karolína Kapitánová, and Peter Mojžíš. "The Effect of Botulinum TOxin Application if Neuro-Ophthalmological Indications on the Results of Schirmer’s Test and Tear Osmolarity." Czech and Slovak Ophthalmology 75, no. 2 (2019): 74–77. http://dx.doi.org/10.31348/2019/2/3.

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Botulinum toxin type A (BT-A) is used in the treatment of neuroophthalmologic disorders such as essential blepharospasm and facial hemispasm for more than 20 years. Although the long-term effect of repeated application of the BT-A was confirmed, the BT-A effect on tears production and retention is not clear. In our work we investigated whether applied BT-A in patients with blepharospasm and hemifacial spasm affect tears production. Tears quality was measured with Schirmer’s and tear osmolarity test during neuro-ophthalmologic diseases treatment, which was evaluated before and 14 days after app
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6

Sumaryadi, Mas Yedi, Dadang Mulyadi Saleh, Aras Prasetiyo Nugroho, Nu'man Hidayat, and Chomsiatun Nurul Hidayah. "Oxytocin Hormone Induction on Milk Production in Relation to Dairy Kid Performance." ANIMAL PRODUCTION 21, no. 3 (2020): 117. http://dx.doi.org/10.20884/1.jap.2019.21.3.747.

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The application of oxytocin induction to milk production in relation to the performance of kids in dairy goats had been carried out in the "PEGUMAS" dairy goat farmer group Gumelar District, Banyumas. This activity aimed to increase milk production and kid performance through the induction of the hormone oxytocin in dairy goats. The approach method was designed in two stages: the first stage carried out the socialization activities and demonstration of techniques for applying IPTEKS, and the second stage applied hormonal technology in the form of oxytocin hormone induction in dairy goats. The
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7

Abbasi, S., and A. Honaramooz. "305 OPTIMIZING DONOR AND RECIPIENT FACTORS IN XENOGRAFTING OF TESTIS TISSUE." Reproduction, Fertility and Development 22, no. 1 (2010): 308. http://dx.doi.org/10.1071/rdv22n1ab305.

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Grafting of donor mammalian testis tissue into recipient mice allows completion of spermatogenesis in the grafted tissue and therefore can serve as a new option for preservation of male germ line. For testis tissue xenografting, castrated male nude mice typically serve as recipients, each receiving 8 testis tissue fragments; however, no study has comprehensively investigated donor and recipient factors. The objective of this study was to determine the effects of strain of immunodeficient recipient mouse (nude v. SCID), gonadal status (intact v. gonadectomized), and gender (male v. female) on t
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8

Li, Xue, Yin Zhang, Hongping Li, Jing Ding, Hui Wan, and Guofeng Guan. "Synthesis of asymmetric [bis(imidazolyl)-BH2]+-cation-based ionic liquids as potential rocket fuels." RSC Advances 11, no. 60 (2021): 38040–46. http://dx.doi.org/10.1039/d1ra07149a.

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Asymmetric [bis(imidazolyl)-BH2]+-cation-based hypergolic ionic liquids are successfully synthesized, which possess a high density-specific impulse ranging from 305.4 to 357.8 s g cm−3, that make them promising candidates for rocket propellants.
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9

Kuznetsova, N. А. "Plankton in the Gulf of Alaska and its contribution to feeding of pacific salmons in spring of 2020." Izvestiya TINRO 204, no. 1 (2024): 160–82. http://dx.doi.org/10.26428/1606-9919-2024-204-160-182.

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Results of the plankton survey conducted in the Gulf of Alaska, including EEZ of Canada, aboard RV Pacific Legacy No. 1 in March-April of 2020 are presented. The samples of plankton were collected in regular grid of stations and processed according to the methodologies adopted in TINRO. The mean total biomass of zooplankton was estimated as 301.9 mg/m3 , of phytoplankton — as 41.9 mg/m3 . The large-sized fraction of zooplankton dominated (on average 214.6 mg/m3 , or 71 % of the total biomass), the portions of the smalland medium-sized fractions were 16 % and 13 %, respectively. Because of spri
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10

Harrower, Michael J., Joseph C. Mazzariello, A. Catherine D’Andrea, et al. "Aksumite Settlement Patterns: Site Size Hierarchies and Spatial Clustering." Journal of Archaeological Research, January 31, 2022. http://dx.doi.org/10.1007/s10814-021-09172-2.

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11

Mills, Ben, James A. Grant-Jacob, Matthew Praeger, Robert W. Eason, Johan Nilsson, and Michalis N. Zervas. "Single step phase optimisation for coherent beam combination using deep learning." Scientific Reports 12, no. 1 (2022). http://dx.doi.org/10.1038/s41598-022-09172-2.

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AbstractCoherent beam combination of multiple fibres can be used to overcome limitations such as the power handling capability of single fibre configurations. In such a scheme, the focal intensity profile is critically dependent upon the relative phase of each fibre and so precise control over the phase of each fibre channel is essential. Determining the required phase compensations from the focal intensity profile alone (as measured via a camera) is extremely challenging with a large number of fibres as the phase information is obfuscated. Whilst iterative methods exist for phase retrieval, i
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12

Sharma, Dilip Kumar, Rajendra Pamula, and D. S. Chauhan. "A contemporary combined approach for query expansion." Multimedia Tools and Applications, July 3, 2020. http://dx.doi.org/10.1007/s11042-020-09172-2.

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13

Bernard, Carole, Oleg Bondarenko, and Steven Vanduffel. "A model-free approach to multivariate option pricing." Review of Derivatives Research, October 27, 2020. http://dx.doi.org/10.1007/s11147-020-09172-2.

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14

Herrera Molina, Pedro Manuel, and Ada Tandazo Rodríguez. "¿Puede perseguir la inspección un supuesto delito fiscal después de haber dictado liquidación sin apreciar indicios delictivos?" Revista de Contabilidad y Tributación. CEF, February 7, 2020, 5–30. http://dx.doi.org/10.51302/rcyt.2020.3575.

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La regulación del delito fiscal presenta unas peculiaridades dirigidas a reforzar la posición de la Administración para recaudar las deudas defraudadas. ¿Resulta compatible este régimen con la posibilidad de denunciar un posible delito después de haberse dictado liquidación? El artículo 197 bis.2 del Reglamento de aplicación de los tributos permitía «apreciar» indicios delictivos «en cualquier momento». Tal precepto ha sido anulado por la Sentencia del Tribunal Supremo de 25 de septiembre de 2019. Esta postura se discute, con vehemencia, en un voto particular. Pensamos –siguiendo al tribunal–
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15

Gooderham, Melinda, Sonja Molin, Robert Bissonnette, et al. "655 - Long-term safety and efficacy of delgocitinib cream for up to 36 weeks in adults with chronic hand eczema: results of the phase 3 open-label extension DELTA-3 trial." British Journal of Dermatology 191, Supplement_2 (2024). http://dx.doi.org/10.1093/bjd/ljae266.034.

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Abstract Introduction/Background In patients with moderate to severe Chronic Hand Eczema (CHE), delgocitinib cream, a topical pan-Janus kinase inhibitor, was well tolerated and demonstrated significant improvement in all efficacy endpoints in DELTA-1 and -2. Objectives The objectives of this study were to evaluate the long-term safety and efficacy of twice-daily applications of delgocitinib cream 20 mg/g as needed for up to 36 weeks in adults with CHE in the Phase 3 open-label DELTA-3 trial (NCT04949841), an extension trial of the 16-week DELTA-1 (NCT04871711) and DELTA-2 (NCT04872101) trials.
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16

Nair, Arjun, Alexander Procter, Steve Halligan, et al. "Chest radiograph classification and severity of suspected COVID-19 by different radiologist groups and attending clinicians: multi-reader, multi-case study." European Radiology, October 25, 2022. http://dx.doi.org/10.1007/s00330-022-09172-w.

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Abstract Objectives To quantify reader agreement for the British Society of Thoracic Imaging (BSTI) diagnostic and severity classification for COVID-19 on chest radiographs (CXR), in particular agreement for an indeterminate CXR that could instigate CT imaging, from single and paired images. Methods Twenty readers (four groups of five individuals)—consultant chest (CCR), general consultant (GCR), and specialist registrar (RSR) radiologists, and infectious diseases clinicians (IDR)—assigned BSTI categories and severity in addition to modified Covid-Radiographic Assessment of Lung Edema Score (C
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