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1

Pellegrini de la Viuda, Tomás Rafael. "Salas Astrain, Ricardo, ed. 2020. Luchas sociales, justicia contextual y dignidad de los pueblos. 330 páginas. Santiago de Chile: Ariadna Ediciones. ISBN: 978-956-8416-92-8." Revista Española de Antropología Americana 51 (May 7, 2021): 263–65. http://dx.doi.org/10.5209/reaa.75968.

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Rastegaeva, M. G., and A. L. Syrkin. "Electrical characteristics of tungsten-contacts to 6HSiC at temperatures between 300 and 950 K." Sensors and Actuators A: Physical 33, no. 1-2 (1992): 95–96. http://dx.doi.org/10.1016/0924-4247(92)80234-t.

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3

Di Biagio, Claudia, Paola Formenti, Lionel Doppler, et al. "Continental pollution in the Western Mediterranean basin: large variability of the aerosol single scattering albedo and influence on the direct shortwave radiative effect." Atmospheric Chemistry and Physics 16, no. 16 (2016): 10591–607. http://dx.doi.org/10.5194/acp-16-10591-2016.

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Abstract. Pollution aerosols strongly influence the composition of the Western Mediterranean basin, but at present little is known on their optical properties. We report in this study in situ observations of the single scattering albedo (ω) of pollution aerosol plumes measured over the Western Mediterranean basin during the TRAQA (TRansport and Air QuAlity) airborne campaign in summer 2012. Cases of pollution export from different source regions around the basin and at different altitudes between ∼ 160 and 3500 m above sea level were sampled during the flights. Data from this study show a larg
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Acharya, Jyoti, Anjana Shrestha, Nisha Rijal, et al. "Multidrug resistant Escherichia coli isolated at National Public Health Laboratory, Nepal." Journal of Nepal Health Research Council 23, no. 01 (2025): 31–41. https://doi.org/10.33314/jnhrc.v23i01.5067.

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Background: Antimicrobial resistance in Escherichia coli is mostly associated with ß-lactamases and carbapenemases enzyme production resulting in treatment challenges. This study was conducted with the aim to detect and characterize antimicrobial resistance in E. coli isolates. Methods: A cross-sectional study was conducted during 2018-2022, at National Public Health Laboratory where the clinical specimens (24636) received were processed for identification and characterization of antimicrobial resistance following conventional & advanced methods. Antibiotic susceptibility tests were perfor
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Lisamy, Sisilia E. A., Charles P. H. Simanjuntak, Ayu Ervinia, et al. "Reproductive aspects of the Japanese threadfin bream, Nemipterus japonicus (Bloch, 1791) in the Southern Java waters (FMA-RI 573)." E3S Web of Conferences 442 (2023): 01025. http://dx.doi.org/10.1051/e3sconf/202344201025.

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This study describes the reproductive biology of the Japanese threadfin bream, Nemipterus japonicus (Bloch, 1791) captured from the Southern Java Waters (FMA-RI 573). Fish monthly sampling collection was conducted from July to December 2022 at three fish landing ports: PPI Ciwaru, PPN Palabuhanratu, and PPI Binuangeun. Overall, 951 individuals consisting of 469 males (49.32%) and 482 females (50.68%), with a size range of 92-300 mm and a weight range of 10–344 g were collected. The sex ratio is balanced (1:1.10), with fecundity ranging from 10,079 to 82,650 eggs. The length at first maturity i
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Guex, J. J., B. Hiltbrand, J. M. Bayon, F. Henri, F. A. Allaert, and M. Perrin. "Anatomical Patterns in Varicose Vein Disease: A Duplex Scanning Study." Phlebology: The Journal of Venous Disease 10, no. 3 (1995): 94–97. http://dx.doi.org/10.1177/026835559501000303.

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Objectives: To determine symptomatology, clinical class, and topographic patterns of varicose veins in a consecutive series of patients with venous complaints. Methods: We performed clinical examination and duplex scanning of 498 lower limbs in 317 patients with obvious varicose veins for whom no previous treatment had been undertaken. Results: Classes of chronic venous insufficiency (CVI) in 498 legs: grade 0: 117 (23.5%); gr 1: 310 (62.2%); gr 2: 47 (9.4%); gr 3: 24 (4.8%). Duplex-detected venous reflux was found in the greater saphenous vein territory (junction or trunk or related perforato
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7

Bajwa, Asif Azeem, Sikandar Ali, Junaid Tahir, Tashfeen Bin Nazir, and Abdullah Asif. "Internet Gaming among Medical Students: Its Impact on Quality of Life." Life and Science 5, no. 4 (2024): 07. http://dx.doi.org/10.37185/lns.1.1.790.

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Objective: To determine the frequency of Internet gaming disorder among medical students and its impact onQuality of life on these students.Study Design: Cross-sectional study.Place and Duration of Study: This study was conducted in a tertiary care Mental Health Facility Armed ForcesInstitute of Mental Health (AFIMH) Rawalpindi, Pakistan from 1st January 2021 to 30th June 2022.Methods: Basic demographic data including age, gender, medical college and year of study amongconsecutively sampled 950 participants was recorded. Each participant was given internet gaming Disorderscore (IGD) and world
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Łukaszewicz, Grzegorz, Michał Tacikowski, Michał Kulka, Krzysztof Chmielarz, Monika Węsierska-Hinca, and Wiesław A. Świątnicki. "Effect of Prior Boriding on Microstructure and Mechanical Properties of Nanobainitic X37CrMoV5-1 Hot-Work Tool Steel." Materials 16, no. 12 (2023): 4237. http://dx.doi.org/10.3390/ma16124237.

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The influence of prior pack boriding on the microstructure and properties of nanobainitised X37CrMoV5-1 hot-work tool steel was investigated in the present work. Pack boriding was conducted at 950 °C for 4 h. Nanobainitising consisted of two-step isothermal quenching at 320 °C for 1 h, followed by annealing at 260 °C for 18 h. A combination of boriding with nanobainitising constituted a new hybrid treatment. The obtained material exhibited a hard borided layer (up to 1822 ± 226 HV0.05) and a strong (rupture strength 1233 ± 41 MPa) nanobainitic core. However, the presence of a borided layer dec
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9

Singh, Suresh Kumar, Narsingh Verma, Shraddha Singh, M. L. Patel, and Anupam Mittal. "Effect of magnesium and zinc supplementation in the patients of essential hypertension." International Journal of Research in Medical Sciences 12, no. 11 (2024): 4136–41. http://dx.doi.org/10.18203/2320-6012.ijrms20243361.

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Background: Primary hypertension is the most common (almost 95%) and it can easily be controlled through lifestyle modification by regular exercise and controlled diet plan. Magnesium and zinc supplementation can alleviate essential hypertension. Methods: 73 hypertensive patients were recruited. Thrice in a row with interval of 5 minutes, twice a day for 7 days high BP monitoring was done and ensured daily intake of Mg (300 mg) and Zn (10 mg) for 4 weeks. Thereafter again 4th week home Blood pressure monitoring was done. Study was done from 25 April 2023 to 24 April 2024. Secondary hypertensio
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Rozhmina, T. A., A. A. Zhuchenko Jr., N. V. Melnikova, and A. D. Smirnova. "Resistance of flax gene pool samples to edaphic stress caused by low acidity." Agricultural Science Euro-North-East 21, no. 2 (2020): 133–40. http://dx.doi.org/10.30766/2072-9081.2020.21.2.133-140.

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In conditions of vegetative trial carried out against selective backgrounds in 2017-2019 the response of 27 flax samples to a decrease in soil acidity to neutral pHKCl was studied. The scheme of the experiment was as follows: variant I (control) − pHKCl 5.3-5.5, P2O5 − 320-340 mg/kg, K2O − 81-92 mg/kg; variant II − pHKCl 6.2, P2O5 − 312-345 mg/kg, K2O − 84-98 mg/kg. It has been shown that during the «herringbone» phase in the majority of studied flax genotypes against the background of pH 6.2, the symptoms of “physiological oppression” of flax were observed: small spots developed on the upper
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11

Pentheroudakis, George E., Anna Batistatou, Urania Dafni, et al. "ESR1 gene amplification and protein expression in 946 patients with resected breast cancer: A Hellenic Cooperative Oncology Group (HeCOG) translational research study." Journal of Clinical Oncology 30, no. 15_suppl (2012): 592. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.592.

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592 Background: Discrepant data have been reported on the incidence of ESR1 gene amplification in breast cancer, its correlation to clinicopathologic characteristics and its impact on prognosis. Methods: Formalin-fixed paraffin-embedded (FFPE) tumor tissue samples from 946 patients participating in two adjuvant chemotherapy phase III trials (HE10/97 and HE10/00) were centrally assessed in tissue microarrays by immunohistochemistry (IHC) for estrogen receptor (ER), progesterone receptor (PgR) and human epidermal growth factor receptor 2 (HER2). FISH was also performed for HER2, TOP2A and ESR1 u
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Wahlbrink, Daiane, Claudete Rempel, Claudete Moreschi, Carmen Neri Fernández Pombo, Daniel Silveira da Silva, and Franciele Dietrich. "PERFIL DE PESSOAS COM HEMOCROMATOSE ATENDIDAS EM UM CENTRO HEMOTERÁPICO DO VALE DO TAQUARI/RS, DE 2008 A 2012." Hygeia - Revista Brasileira de Geografia Médica e da Saúde 13, no. 24 (2017): 189–98. http://dx.doi.org/10.14393/hygeia1330192.

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Estudo transversal, retrospectivo que verifica o perfil de pessoas com hemocromatose registradas no Centro Hemoterápico do Vale do Taquari (Hemovale), RS/Brasil atendidas de 2008 a 2012. Foram coletadas, através de registros documentais as variáveis: prevalência de hemocromatose (PH) sexo, idade, peso, pressão arterial (PA), frequência cardíaca (FC), temperatura axilar (TA), volume de sangue retirado para flebotomia e hematócrito. A PH foi de 285 casos. Os homens correspondem a 92% das pessoas atendidas no hemocentro. A faixa etária variou de 24 a 81 anos, sendo que a média de idade foi de
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Atoma, Charity Nwamaka, Elizabeth Chidinma Mube-William, and Olufemi Martins Adesope. "Perceived soft skills needs of agriculture students in public universities in Niger Delta, Nigeria." Journal of Agricultural Extension 27, no. 4 (2023): 13–19. http://dx.doi.org/10.4314/jae.v27i4.2.

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The study investigated the perceived soft skills needs of agriculture students in public universities in the Niger Delta area of Nigeria. The population of the study is 11,283 agriculture undergraduate students in the 12 public universities in states in the Niger Delta geo-political zone. The sample size was 300 agriculture undergraduate students. Multistage sampling procedure was used to select the sample. The instrument for data collection was a questionnaire. Percentage and mean were used for analysis. Results revealed that the majority of the respondents (97.2%) could communicate effective
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Wang, Jinghong, Yeqiang Shu, Dongxiao Wang, et al. "Observed 10–20-Day Deep-Current Variability at 5°N, 90.5°E in the Eastern Indian Ocean." Journal of Physical Oceanography 54, no. 2 (2024): 521–36. http://dx.doi.org/10.1175/jpo-d-23-0082.1.

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Abstract In the eastern off-equatorial Indian Ocean, deep current intraseasonal variability within a typical period of 10–20 days was revealed by a mooring at 5°N, 90.5°E, accounting for over 50% of the total bottom subtidal velocity variability. The 10–20-day oscillations were more energetic in the cross-isobathic direction (STD = 3.02 cm s−1) than those in the along-isobathic direction (STD = 1.50 cm s−1). The oscillations were interpreted as topographic Rossby waves (TRWs) because they satisfied the TRWs dispersion relation that considered the smaller Coriolis parameter and stronger β effec
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15

Shah, Binay K., Krishna B. Ghimire, and Dinesh Pendharkar. "Survival Trends Among Very Elderly Patients with Advanced Diffuse Large B-Cell Lymphoma - a Population Based Study." Blood 124, no. 21 (2014): 2640. http://dx.doi.org/10.1182/blood.v124.21.2640.2640.

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Abstract Background Rituximab became commercially available in Novermber 1997. It was FDA approved in February 2006 for the first line treatment of patients with advanced diffuse large B cell lymphoma (DLBCL). The incidence of diffuse large B cell lymphoma increases with age, with >100 cases per 100000 persons aged >80 years. There is a limited data on survival very elderly patients with DLBCL. This study was conducted to evaluate survival trends of very elderly (≥80 years) patients with advanced DLBCL in the United States. Methods We selected very elderly patients (age ≥80 years) diagno
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16

Mailankody, Sham, Andrzej J. Jakubowiak, Myo Htut, et al. "Orvacabtagene autoleucel (orva-cel), a B-cell maturation antigen (BCMA)-directed CAR T cell therapy for patients (pts) with relapsed/refractory multiple myeloma (RRMM): update of the phase 1/2 EVOLVE study (NCT03430011)." Journal of Clinical Oncology 38, no. 15_suppl (2020): 8504. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.8504.

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8504 Background: Orva-cel is an investigational, BCMA-directed CAR T cell product with a fully human binder. Over 100 pts have been treated in the EVOLVE phase 1 study. Pts treated at 50 and 150 × 106 CAR+ T cells were previously reported (Mailankody ASH 2018 #957). We now report results of the higher dose levels (DLs) in 51 pts who received orva-cel manufactured using the process intended to support commercial use. Methods: Pts with RRMM who had ≥3 prior regimens, a proteasome inhibitor (PI), an immunomodulatory drug (IMiD), and an anti-CD38 monoclonal antibody (mAb), received orva-cel at 300
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Dokic, Ljubisa, Dragan Delic, Olga Dulovic, Milos Korac, Branko Milosevic, and Lidija Lavadinovic. "The frequency of pathological ultrasonographic findings of the gallbladder in patients with infectious diseases." Medical review 60, no. 1-2 (2007): 89–92. http://dx.doi.org/10.2298/mpns0702089d.

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Introduction The objective of our study was to establish, through retrospective analysis of sonographic findings obtained by portable ultrasound devices, the frequency of pathological findings of the gallbladder and common bile duct in a randomized group of patients with infectious diseases. Material and methods During five years (January 1, 2000 - December 31, 2004), gallbladder and common bile duct were examined by ultrasonography in 2691 adult patients (1440 males and 1251 females), mean age 48?17 years, ranging from 17 to 92 years at the Institute of Infectious and Tropical Diseases in Bel
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Ahmed, Md Shakeel, Imranul Mawa, Ayesha Ahmed Khan, and Md Abdullah al Mamun. "Bacteriological Profile and Antibiotic Susceptibility Pattern of Isolates from Suspected Neonatal Septicemia Patients in Different Hospitals of Chattogram." IAHS Medical Journal 7, no. 1 (2024): 68–73. http://dx.doi.org/10.3329/iahsmj.v7i1.77576.

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Background: Bacterial blood stream infection is an important cause of morbidity and mortality in neonates. This study was undertaken to identify the bacterial isolates from suspected neonatal septicemia patients and to understand their antimicrobial susceptibility pattern in Chattogram. Materials and methods: A cross-sectional descriptive type of study was done for a period of two years from January 2022 to December 2023. Blood samples from 340 neonates with clinically suspected septicemia were taken for automated culture and susceptibility test was conducted in Bacteriology Laboratory of Ibne
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Mbopi-Kéou, François-Xavier, Stefano Mion, Bertrand Sagnia, and Laurent Bélec. "Validation of a Single-Platform, Volumetric, CD45-Assisted PanLeucogating Auto40 Flow Cytometer To Determine the Absolute Number and Percentages of CD4 T Cells in Resource-Constrained Settings Using Cameroonian Patients' Samples." Clinical and Vaccine Immunology 19, no. 4 (2012): 609–15. http://dx.doi.org/10.1128/cvi.00023-12.

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ABSTRACTThe study evaluated the single-platform, volumetric, CD45-assisted PanLeucogating Auto40 flow cytometer (Apogee Flow Systems Ltd., Hemel Hempstead, United Kingdom) for CD4 T cell numeration, compared to the reference FACSCalibur flow cytometer. Results of absolute counts and percentages of CD4 T cells by Auto40 and FACSCalibur of 234 tripotassium EDTA (K3-EDTA)-blood samples from 146 adults and 88 children (aged from 18 months to 5 years), living in Yaoundé, Cameroon, were highly correlated (r2= 0.97 andr2= 0.98, respectively). The mean absolute bias and relative bias between Apogee Au
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RIBEIRO, Rebeca Sadigursky, Glícia Estevam de ABREU, Eneida Regis DOURADO, Maria Luiza VEIGA, Victoria Andrade LOBO, and Ubirajara BARROSO JR. "BLADDER AND BOWEL DYSFUNCTION IN MOTHERS AND CHILDREN: A POPULATION-BASED CROSS-SECTIONAL STUDY." Arquivos de Gastroenterologia 57, no. 2 (2020): 126–30. http://dx.doi.org/10.1590/s0004-2803.202000000-23.

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ABSTRACT BACKGROUND: Recently it was shown an association between lower urinary tract symptoms in mothers and their children. However, the role of functional constipation in this binomial is unclear. OBJECTIVE: To evaluate bladder and bowel dysfunction between mothers and children. METHODS: A population-based cross-sectional study. Mothers and their children responded a self-administrated questionnaire composed by Rome IV criteria, International Consultation on Incontinence Questionnaire - Overactive Bladder, Dysfunctional Voiding Scoring System and demographic questions. RESULTS: A total of 4
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21

Richardson, P. G., A. Chanan-Khan, S. Lonial, et al. "Tanespimycin (T) + bortezomib (BZ) in multiple myeloma (MM): Pharmacology, safety and activity in relapsed/refractory (rel/ref) patients (Pts)." Journal of Clinical Oncology 25, no. 18_suppl (2007): 3532. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.3532.

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3532 Background: Tanespimycin (17-AAG/KOS 953) disrupts Hsp90, a molecular chaperone of MM client proteins including IL-6 and IGF-1R that are key to MM growth, survival and drug resistance. Single agent T was well tolerated with modest anti- MM activity. Preclinical studies suggest potential synergy with BZ. Methods: Pts received BZ as IVB followed by 1-hr infusion of T on D1,4,8,11 q 21d. Results: 49 pts were enrolled in 7 cohorts (T 100- 340 mg/m2; BZ 0.7 - 1.3 mg/m2). PK of T was similar with or without BZ. Inhibition of 20S proteasome with T+BZ was not different vs. historical BZ single ag
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Family, Leila, Su-Jau Yang, Zandra Klippel, et al. "Risk of Febrile Neutropenia (FN) in Select Myelosuppressive Chemotherapy Regimens." Blood 126, no. 23 (2015): 3257. http://dx.doi.org/10.1182/blood.v126.23.3257.3257.

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Abstract Introduction Febrile neutropenia (FN) is a serious adverse effect of myelosuppressive chemotherapy, which often results in hospitalization and chemotherapy dose modification. FN risk depends on patient characteristics and chemotherapy regimen risk. Understanding the FN risk associated with individual chemotherapy regimens can help guide the use of prophylactic granulocyte colony-stimulating factor (G-CSF) and patient monitoring. To this end, the NCCN has classified regimens into high (≥20%), intermediate (10%-20%), or low (<10%) FN risk based primarily on clinical trial data. Howev
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Safarova, К. N., E. A. Fedotov, and A. P. Rebrov. "Serum concentrations of interleukin-6 and tumor necrosis factor alpha in patients with spondyloarthritis: a relationship between systemic inflammation and anemia." Bulletin of Siberian Medicine 21, no. 2 (2022): 115–21. http://dx.doi.org/10.20538/1682-0363-2022-2-115-121.

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Aim. To assess the relationship between the activity of systemic inflammation and the hemoglobin level in patients with spondyloarthritis (SpA).Materials and methods. We examined 92 patients with SpA aged 42.9 ± 11.6 years (SpA duration – 14.8 ± 9.6 years, 55 (60%) men). We calculated the BASDAI and ASDAS-CRP scores, performed complete blood count, evaluated erythrocyte sedimentation rate (ESR), ferrokinetic parameters, C-reactive protein (CRP) level, and serum concentrations of tumor necrosis factor α (TNF-α) and interleukin-6 (IL-6).Results. Anemia was found in 52 (57%) patients: 13 (25%) pa
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Philip, T., R. Ghalie, R. Pinkerton, et al. "A phase II study of high-dose cisplatin and VP-16 in neuroblastoma: a report from the Société Française d'Oncologie Pédiatrique." Journal of Clinical Oncology 5, no. 6 (1987): 941–50. http://dx.doi.org/10.1200/jco.1987.5.6.941.

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Forty-seven children or adolescents with initial stage IV (42 patients) or stage III (five) advanced neuroblastoma (12 were progressing after relapse and 35 had never reached complete remission [CR] after conventional therapy) were included in a phase II study of the combination of high-dose VP-16 (100 mg/m2/d X 5) and high-dose cisplatin (CDDP) (40 mg/m2/d X 5). Twenty patients had received prior CDDP therapy (total dose, 100 to 640 mg/m2; median, 320 mg/m2) and 38 of 47 had bone marrow involvement when included in the study. The overall response rate was 55%, with 22% CR. Duration of respons
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Latagliata, Roberto, Dario Ferrero, Francesco Cavazzini, et al. "Imatinib In Very Elderly CML Patients: What Can We Achieve?." Blood 116, no. 21 (2010): 1229. http://dx.doi.org/10.1182/blood.v116.21.1229.1229.

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Abstract Abstract 1229 In the “real world” of clinical practice, many very elderly CML patients have been treated with imatinib (IM), but there are few data on the results and the best initial dosage in such patients. To highlight peculiar aspects of toxicity and efficacy of IM in this subset which accounts for at least 10–15% of all CML cases, we retrospectively revised 156 CML patients in chronic phase treated with IM when aged > 75 years from 23 haematological Institutions in Italy; there were 85 males and 71 females, median age at IM start was 78.4 years (IR 76.1 – 81.4), Sokal Risk at
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Masarova, Lucia, Naval Daver, Naveen Pemmaraju, et al. "Do Patients with Post-Essential Thrombocythemia and Post-Polycythemia Vera Differ from Patients with Primary Myelofibrosis?" Blood 126, no. 23 (2015): 4069. http://dx.doi.org/10.1182/blood.v126.23.4069.4069.

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Abstract Introduction: Clinical characteristics of post-essential thrombocythemia/polycythemia vera myelofibrosis "post ET/PV-MF" are not well defined as for primary myelofibrosis "MF". Objective: We aimed to identify morphological, clinical and prognostic characteristics of patients with post ET/PV-MF seen at our center. Methods: Retrospective chart review of 1120 patients with MF - 766 primary MF, 354 post ET/PV-MF, who were referred to our institution between years 1984-2013 was performed; 92% presented after the year of 2000. Fisher's exact and Mann-Whitney test were used for categorical a
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Moldenhauer, Patrick, Carl Linderholm, Magnus Rydén, and Anders Lyngfelt. "Avoiding CO2 capture effort and cost for negative CO2 emissions using industrial waste in chemical-looping combustion/gasification of biomass." Mitigation and Adaptation Strategies for Global Change 25, no. 1 (2019): 1–24. http://dx.doi.org/10.1007/s11027-019-9843-2.

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Abstract Chemical-looping combustion (CLC) is a combustion process with inherent separation of carbon dioxide (CO2), which is achieved by oxidizing the fuel with a solid oxygen carrier rather than with air. As fuel and combustion air are never mixed, no gas separation is necessary and, consequently, there is no direct cost or energy penalty for the separation of gases. The most common form of design of chemical-looping combustion systems uses circulating fluidized beds, which is an established and widely spread technology. Experiments were conducted in two different laboratory-scale CLC reacto
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Maxwell, Lauren, Arijit Nandi, Andrea Benedetti, Karen Devries, Jennifer Wagman, and Claudia García-Moreno. "Intimate partner violence and pregnancy spacing: results from a meta-analysis of individual participant time-to-event data from 29 low-and-middle-income countries." BMJ Global Health 3, no. 1 (2018): e000304. http://dx.doi.org/10.1136/bmjgh-2017-000304.

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IntroductionInadequately spaced pregnancies, defined as pregnancies fewer than 18 months apart, are linked to maternal, infant, and child morbidity and mortality, and adverse social, educational and economic outcomes in later life for women and children. Quantifying the relation between intimate partner violence (IPV) and women’s ability to space and time their pregnancies is an important part of understanding the burden of disease related to IPV.MethodsWe applied Cox proportional hazards models to monthly data from the Demographic and Health Surveys’ Reproductive Health Calendar to compare in
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Gatama, Samwel Njenga, Mary Akinyi Otieno, and Samuel Ndungu Waweru. "Principals` Instructional Leadership and Its Influence on Students’ Academic Achievement in Public Secondary Schools in Nyeri and Nyandarua Counties in Kenya." East African Journal of Education Studies 6, no. 1 (2023): 148–63. http://dx.doi.org/10.37284/eajes.6.1.1080.

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The study focused on the influence of principals` instructional leadership practices on students` academic performance in public secondary schools in Nyeri and Nyandarua counties. The concern was the low and widely varied academic performance yet the principals` instructional leadership practices were not clear. The study adopted ex-post facto research design and systems theory to study instructional leadership as a determinant of learning outcomes. The sample size comprised 192 principals, 330 Heads of Department, and 352 teachers in 192 schools. The main data collection tools were the princi
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Gonzalez-Barcena, David, Manuel Vadillo Buenfil, Emilo Garcia Procel, et al. "Inhibition of luteinizing hormone, follicle-stimulating hormone and sex-steroid levels in men and women with a potent antagonist analog of luteinizing hormone-releasing hormone, Cetrorelix (SB-75)." European Journal of Endocrinology 131, no. 3 (1994): 286–92. http://dx.doi.org/10.1530/eje.0.1310286.

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Gonzalez-Barcena D, Vadillo Buenfil M, Garcia Procel E, Guerra-Arguero L, Cardenas Cornejo I, Comaru-Schally AM, Schally AV. Inhibition of luteinizing hormone, follicle-stimulating hormone and sex-steroid levels in men and women with a potent antagonist analog of LH-RH, Cetrorelix (SB-75). Eur J Endocrinol 1994;131:286–92. ISSN 0804–4643 Cetrorelix (SB-75; [Ac-d-Nal(2)1, d-Phe(4Cl)2, d-Pal(3)3, d-Cit6, d-Ala10] luteinizing hormone-releasing hormone (LHRH)) is a new highly potent antagonist analog of LHRH containing the d-ureidoalkyl amino acid d-citrulline at position 6 and is free of allergen
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31

Walters, E. M., J. D. Benson, A. Rieke, J. K. Graham, and J. K. Critser. "80 CHOLESTEROL-LOADED METHYL-BETA-CYCLODEXTRIN IMPROVES BOAR SPERMATOZOA CRYOPROTECTANT ADDITION AND REMOVAL TOLERANCE." Reproduction, Fertility and Development 21, no. 1 (2009): 140. http://dx.doi.org/10.1071/rdv21n1ab80.

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Difficulties associated with the cryopreservation of boar sperm include their sensitivities to osmotic stresses and chilling sensitivity. We investigated the effects of cholesterol-loaded cyclodextrin (CLC) on boar sperm motility and membrane integrity following exposure to various osmolalities. Samples were collected using the gloved hand method from crossbred boars, and ejaculates having greater than 75% motility were extended 1:3 with Androhep (Minitube Inc., Verona, WI) for this study. Samples were centrifuged at 700g for 5 min, and the resulting pellets were resuspended to 1.2 × 108 cells
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32

Mahmoud, Fathi Sakr, Yousef Koraitim Tarek, Abdel Haleem Mohamed Waleed, and Ibrahim fleafe Mohamed. "Factors affecting treatment outcome in patients with Acute Mesenteric Ischemia." Biolife 5, no. 1 (2022): 100–104. https://doi.org/10.5281/zenodo.7360489.

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<strong>ABSTRACT</strong> <strong>Background:</strong> Acute mesenteric ischemia (AMI) is a syndrome caused by inadequate blood flow through the mesenteric vessels, resulting in ischemia and eventual gangrene of the bowel wall. It may be classified as either arterial or venous. The purpose was to investigate the factors affecting the treatment outcome of the patients presenting with acute mesenteric ischemia. <strong>Methods:</strong> This study included 50 adult patients admitted with AMI at the Alexandria Main University Hospital from January 2014 to January 2015. Analysis of the factors, Ag
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33

Gusev, A. I., A. A. Usol’tsev, N. A. Kozyrev, N. V. Kibko, and L. P. Bashchenko. "Development of flux-cored wire for surfacing of parts operating under conditions of wear." Izvestiya Visshikh Uchebnykh Zavedenii. Chernaya Metallurgiya = Izvestiya. Ferrous Metallurgy 61, no. 11 (2018): 898–906. http://dx.doi.org/10.17073/0368-0797-2018-11-898-906.

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Powder wire for surfacing of abrasive-wearing products of Fe - C - Si - Мп - Cr -Ni - Mo system (type A according to IIW classification) was developed and investigated. Studies in laboratory conditions were performed according to the following scheme: multilayer surfacing of the samples was carried out with preheating of plates up to 350 °C and subsequent slow cooling (after surfacing). Surfacing was made by ASAW-1250 welding tractor with manufactured cored wire in six layers on plates of 09G2S steel. Instead of amorphous carbon, carbon-fluorine-containing dust containing 21 - 46 % Al2O3; 18 -
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34

Peterson, Erica A., Paul R. Yenson, Jacobus C. Kritzinger, et al. "Prospective Study of an Inferior Vena Cava Filter Management Pathway in a Tertiary Care and Trauma Centre." Blood 124, no. 21 (2014): 685. http://dx.doi.org/10.1182/blood.v124.21.685.685.

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Abstract Background: In our institution, a retrospective analysis of inferior vena cava (IVC) filter usage demonstrated attempted removal in only 60% of patients. We performed a prospective cohort study to determine if an IVC filter management program (IVCFP) will improve retrieval rates. Methods: Consecutive patients receiving a retrievable IVC filter were approached for study enrollment within 48 hours of placement. Consenting patients received a visible “IVC Filter Identification Wristband” and pre-printed orders were placed in each patient's chart indicating that the wristband can only be
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35

Sych, Z., and S. Kubrak. "Evaluation of varieties and local forms of winter garlic for their economic characteristics in the conditions of right bank Forest Steppe of Ukraine." Agrobìologìâ, no. 1(157) (May 25, 2020): 169–74. http://dx.doi.org/10.33245/2310-9270-2020-157-1-169-174.

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Garlic production for the local market and for export lacks a suffi cient amount of high-yielding varieties with large bulbs and small amount of cloves, resistant to pests, diseases and stressful cultivation conditions. In addition to industrial varieties, adapted local forms of self-breeding are currently cultivated. Winter garlic is a plant with vegetative reproduction and it is reproduces with cloves, single clove and air bulbs, Therefore, the varieties brought from other regions degenerate quickly. Two and three times reproduction leads to a gradual reduction in yield and quality. The tran
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36

Massuti, B., A. Gómez, J. Sastre, et al. "Randomized phase III trial of the TTD Group comparing capecitabine and oxaliplatin (XELOX) vs. oxaliplatin and 5-fluorouracil in continuous infusion (FUFOX) as first line treatment in advanced or metastatic colorectal cancer (CRC)." Journal of Clinical Oncology 24, no. 18_suppl (2006): 3580. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.3580.

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3580 Background: OX plus CI 5-FU is one of the standard chemotherapy regimens for first-line treatment in patients (p) with advanced CRC. Phase II trials have shown XELOX as a convenient combination, with a high activity and a favourable safety profile. This study is a phase III trial comparing both schedules. Methods: Multicenter, randomized and open labeled study was designed to include p withadvanced/metastatic CRC adenocarcinoma, measurable disease, PS ≥70% and adequate bone marrow, renal and hepatic functions. Previous adjuvant chemotherapy was allowed. Primary endpoint is time to progres
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37

Tsai, Stephanie B., Hongtao Liu, Tsiporah B. Shore, et al. "Frequency and Risk Factors of Cord Graft Failure (CGF) Following Reduced Intensity Conditioning Haplo-Cord Hematopoietic Stem Cell Transplantation." Blood 124, no. 21 (2014): 2463. http://dx.doi.org/10.1182/blood.v124.21.2463.2463.

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Abstract PURPOSE: Delayed engraftment and cord graft failure (CGF) are serious and often fatal complications after unrelated cord blood (UCB) hematopoietic cell transplantation (HCT), precluding use of low cell dose UCB. The haplo-cord HCT approach allows the use of a lower dose single UCB unit by co-infusion of a CD34+ selected haploidentical graft. Although haplo-cord HCT aims to achieve durable UCB hematopoiesis, the haplo graft provides early temporary engraftment. We describe the frequency, complications and risk factors of CGF after haplo-cord HCT after reduced-intensity conditioning (RI
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38

Fresneau, Brice, Felicia Santos, Rodrigue Allodji, et al. "New insights in cisplatin and radiation-induced ototoxicity: A French Childhood Cancer Survivors Study (FCCSS)." Journal of Clinical Oncology 37, no. 15_suppl (2019): 10061. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.10061.

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10061 Background: Platinum chemotherapy (CT) and cranial radiotherapy (RT) are risk factors of ototoxicity. Effects of RT dose at inner ear and of other CT were investigated. Methods: Of 7670 5-year childhood cancer survivors from the FCCSS treated before 20 years of age in 1942-2000 for solid cancer or lymphoma, 5243 with ototoxicity long-term follow-up data were included. Severe ototoxicity, defined as the need of hearing aids or Brock grade 3-4 hearing loss, was identified from self-administrated questionnaires, clinical visits and cohort linkage with the French Hospital Database and health
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39

Li, Jinhui, Minji Jung, Benjamin Chung, Mark Preston, Marvin Langston, and Rebecca Graff. "Abstract 2294: Association of analgesic use with risk of renal cell cancer in the Nurses’ Health Studies." Cancer Research 85, no. 8_Supplement_1 (2025): 2294. https://doi.org/10.1158/1538-7445.am2025-2294.

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Abstract Objectives: This study aims to investigate the association between commonly utilized analgesics—aspirin, non-aspirin nonsteroidal anti-inflammatory medications (NSAIDs), and acetaminophen and the risk of renal cell cancer (RCC) in women. Methods: In 1980, the Nurses’ Health Study (NHS) collected data on aspirin usage from 92, 125 women. Additional non-aspirin NSAIDs and acetaminophen were included in 1990. In 1989, 112, 292 women were collected data in the NHS II and followed up since 1989. The association was also further investigated by stratification of histological subtypes, patho
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40

Richardson, Paul G., Asher Chanan-Khan, Sagar Lonial, et al. "Tanespimycin (T) + Bortezomib (BZ) in Multiple Myeloma (MM): Confirmation of the Recommended Dose Using a Novel Formulation." Blood 110, no. 11 (2007): 1165. http://dx.doi.org/10.1182/blood.v110.11.1165.1165.

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Abstract Introduction: Tanespimycin (17-AAG/KOS-953) disrupts Hsp90, a molecular chaperone of client proteins including IL-6 and IGF-1R, key to MM growth, survival and drug resistance. Single agent T is well tolerated with modest anti-MM activity in Phase 1; preclinical studies suggest synergy with BZ. Methods: To date, 63 patients (pts) received BZ followed by 1-hr infusion of T on D1,4,8,11 q 21d. Dose escalating phase: 36 pts were enrolled in 7 cohorts (T 100–340 mg/m2; BZ 0.7–1.3 mg/m2). Confirmation of the phase 2 dose occurred in 27 pts across 2 groups: 1 group received a Cremophor formu
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41

Khanna, D., C. J. F. Lin, H. Spotswood, J. Siegel, D. Furst, and C. Denton. "THU0328 SAFETY AND EFFICACY OF SUBCUTANEOUS TOCILIZUMAB IN SYSTEMIC SCLEROSIS: RESULTS FROM THE OPEN-LABEL PERIOD OF THE PHASE 3 FOCUSSCED TRIAL." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 394.1–394. http://dx.doi.org/10.1136/annrheumdis-2020-eular.1535.

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Background:The anti–interleukin-6 (IL-6) receptor-α antibody tocilizumab (TCZ) demonstrated skin score improvement and forced vital capacity (FVC) preservation in patients with systemic sclerosis (SSc) in a phase 2 randomized controlled trial.1,2Data from the 48-week, double-blind (DB), placebo (PBO)-controlled period of the focuSSced phase 3 trial were previously presented,3and open-label (OL) data up to week 96 are presented herein.Objectives:To assess the long-term safety and efficacy of TCZ in SSc patients.Methods:Adult patients with active SSc (≤60-month duration, modified Rodnan skin sco
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42

Söylemez, H., S. N. İspir, H. R. Demirel, E. Yıldız, and M. Aydın. "Evaluation of Relationship of Neutrophil/Lymphocyte, Platelet/Lymphocyte, Monocyte/Lymphocyte Monocyte/HDL Ratios and Systemic Immune Inflammatory Index Value with Antipsychotic Treatments in Schizophrenic Patients." European Psychiatry 67, S1 (2024): S173. http://dx.doi.org/10.1192/j.eurpsy.2024.382.

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IntroductionThere are studies showing that the systemic inflammation response in patients diagnosed with schizophrenia is different from healty controls. Neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (TLR), monocyte-lymphocyte ratio (MLR), monocyte-HDL ratio (MHO) and systemic immune inflammation index (SII) have recently been used as inflammation indicators.ObjectivesNLR, TLR, MLR, MHO and SII have been evaluated in many studies in schizophrenia patients. The aim of our study is to evaluate the relationship between NLR, TLR, MLR, MHO, SII values and antipsychotic treatments of
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43

Constantin, Joanne, Genevieve M. Kenney, Kosali Simon, and Kao-Ping Chua. "Medicaid Unwinding and Changes in Buprenorphine Dispensing." JAMA Network Open 8, no. 5 (2025): e258469. https://doi.org/10.1001/jamanetworkopen.2025.8469.

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ImportanceAfter the Medicaid continuous enrollment provision ended on March 31, 2023, millions of Medicaid patients were disenrolled, a process called “Medicaid unwinding.” Whether this process was associated with changes in dispensing of buprenorphine, a medication for opioid use disorder preventing opioid overdose deaths, is unknown.ObjectiveTo evaluate changes in buprenorphine dispensing during Medicaid unwinding.Design, Setting, and ParticipantsThis cross-sectional study used difference-in-differences analysis to assess data from the IQVIA Longitudinal Prescription Database, capturing 92%
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44

Den Broeder, N., L. M. Verhoef, Y. A. De Man, et al. "POS0652 LONG-TERM EFFECTIVENESS OF ULTRA-LOW DOSES OF RITUXIMAB IN RHEUMATOID ARTHRITIS." Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 597.2–598. http://dx.doi.org/10.1136/annrheumdis-2022-eular.2903.

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BackgroundThe optimal rituximab (RTX) dose for the treatment of rheumatoid arthritis remains unclear. RTX treatment of 1000mg per 6 months and 2000mg per 6 months were shown to be similarly efficacious (1). The REDO trial showed comparable the 6-month efficacy of continued treatment with 500mg and 200mg compared to 1000mg, though formal non-inferiority could not be established (2).ObjectivesTo assess the long-term effects of ultra-low dose RTX (1×500mg and 1×200mg) in RA patients previously responding well to conventional low dose RTX (1×1000mg).MethodsPatients from the REDO trial were invited
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45

Ravichandran, N., N. Sandhu, A. Nune, et al. "POS0558 FLARES OF AUTOIMMUNE RHEUMATIC DISEASE FOLLOWING COVID-19 INFECTION: OBSERVATIONS FROM THE COVAD STUDY." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 546–47. http://dx.doi.org/10.1136/annrheumdis-2023-eular.3976.

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BackgroundViral infections can trigger flare of autoimmune rheumatic diseases through upregulation of interferon axis. However, global data on flares of AIRDs following COVID-19 infection is scarce.ObjectivesWe aimed to study the prevalence and characteristics of patient-self reported flare of AIRDs following COVID-19 infection as part of the ongoing COVID-19 Vaccination in Autoimmune Diseases (COVAD) study.MethodsThe COVAD study, a cross-sectional patient-self reported electronic survey (157 collaborators, 106 countries) collected data on COVID-19 infection, vaccination and flares among AIRDs
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46

Rathi, Nisha, Andrew Dinh, Sajid A. Haque, et al. "Outcomes of High Dose Steroid Treatment with or without Aminocaproic Acid in Critically Ill Stem Cell Transplant Recipients with Diffuse Alveolar Hemorrhage." Blood 118, no. 21 (2011): 3058. http://dx.doi.org/10.1182/blood.v118.21.3058.3058.

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Abstract Abstract 3058 Background: Diffuse alveolar hemorrhage (DAH) complicates Hematopoietic Stem Cell Transplantation (HSCT) at a rate of 2–14%, and carries a mortality of 70 to 100%. For transplant patients that require intensive care unit (ICU) admission, the prevalence of DAH may be as high as 40%. Patients present with diffuse alveolar infiltrates with or without hemoptysis, and are diagnosed based on bronchoscopic and clinical findings. Retrospective studies have shown that high dose steroid therapy may improve outcomes and has thus been the traditional modality of treatment. A recent
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47

Mcinnes, I., J. F. Merola, P. J. Mease, et al. "SAT0403 EFFICACY AND SAFETY OF 108 WEEKS’ BIMEKIZUMAB TREATMENT IN PATIENTS WITH PSORIATIC ARTHRITIS: INTERIM RESULTS FROM A PHASE 2 OPEN-LABEL EXTENSION STUDY." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 1153–54. http://dx.doi.org/10.1136/annrheumdis-2020-eular.1850.

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Background:Bimekizumab (BKZ), a monoclonal antibody that selectively neutralises IL-17A and IL-17F, has shown clinical improvements in skin and joint outcomes over 48 weeks (wks) in patients (pts) with active psoriatic arthritis (PsA).1Objectives:To report 2-year interim results from a phase 2b dose-ranging study (BE ACTIVE;NCT02969525) and open-label extension (OLE;NCT03347110) of BKZ in pts with PsA.Methods:Design of the dose-ranging study is described elsewhere.1Pts who completed 48 wks’ BKZ treatment without meeting withdrawal criteria were eligible for OLE entry. All OLE pts received BKZ
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48

Moyers, Justin Tyler, Danielle Brazel, Priyanka Kumar, et al. "Abstract 2184: Landscape of genomic alterations of ultra-rare sarcomas (URS) from 1,079 patients in the AACR GENIE real world database: Clinical implications." Cancer Research 82, no. 12_Supplement (2022): 2184. http://dx.doi.org/10.1158/1538-7445.am2022-2184.

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Abstract Introduction: Sarcomas are heterogenous tumors of more than 150 different tumor types. Recently, 56 soft tissue (ST-URS) and 21 bone (B-URS) sarcomas were classified as URS based on incidence of less than 1 in a million by the Connective Tissue Oncology Society. There is only one histology-based treatment approved in URS. Methods: AACR GENIE database cBioPortal were accessed. Individual alterations annotated by OncoKB therapeutic evidence level, TCGA PanCancer pathway alterations, and demographic data were gathered. Detailed cancer type was reclassified into genomically distinct disea
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49

O., Ademila, Akingboye A. S., and Ojamomi A. I. "Radiometric survey in geological mapping of basement complex area of parts of Southwestern Nigeria." VIETNAM JOURNAL OF EARTH SCIENCES 40, no. 3 (2018): 288–98. http://dx.doi.org/10.15625/0866-7187/40/3/12619.

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Radiometric methods were used to investigate the radioactive properties of rocks in parts of southwestern Nigeria with a view to interpreting the geological structure and abundance of natural radioactive elements in the main type rocks. The airborne radiometric dataset of Ikole Sheet and ground radiometric data recorded from eight traverses in Akoko axis of the study area were processed. Results presented as maps and profiles displayed variations of high and low radioactive concentrations across the area. These maps showed moderate to very high concentrations and very low to low concentrations
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50

Koch, Cody A., Terra L. Lasho, and Ayalew Tefferi. "Comparison of Platelet-Rich Plasma Serotonin Level and Quantitative Neutrophil PRV-1 Assay in Chronic Myeloproliferative Disorders." Blood 104, no. 11 (2004): 4740. http://dx.doi.org/10.1182/blood.v104.11.4740.4740.

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Abstract In a prospective study of 100 subjects, an ELISA assay was used to measure platelet-rich plasma (PRP) serotonin levels in patients with polycythemia vera (PV; n=26), essential thrombocythemia (ET; n=14), myelofibrosis with myeloid metaplasia (MMM; n=26), secondary or spurious polycythemia (SP; n=20) and controls (n=14). Neutrophil PRV-1 expression was concurrently assayed by real-time PCR in 69 patients (23 PV, 17 SP, 12 ET, 7 MMM, 10 controls). Table 1 outlines the median and range of measured values across the different study groups. Table 1 Controls SP PV ET MMM Age in years N/A 49
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