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Artículos de revistas sobre el tema "ACVB"

Autor: Grafiati

Publicado: 4 de junio de 2021

Última modificación: 13 de febrero de 2022

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1

Zheng, Y. Z., G. P. Wang, N. Hong, J. F. Zhou, Z. K. Yang, and N. Hong. "First Report of Actinidia virus A and Actinidia virus B on Kiwifruit in China." Plant Disease 98, no. 11 (2014): 1590. http://dx.doi.org/10.1094/pdis-04-14-0420-pdn.

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At present, two viruses affecting kiwifruit (Actinidia spp.), Actinidia virus A (AcVA) and Actinidia virus B (AcVB), both belonging to the genus Vitivirus in the family Betaflexiviridae, have been reported from New Zealand (2). The infected trees showed leaf vein chlorosis, flecking, and ringspots. China is the largest commercial kiwifruit producer. During field investigations in the growing season of 2013, symptoms of leaf chlorosis or ringspots, similar to those caused by AcVA and AcVB (1), were observed on some kiwifruit (Actinidia chinensis) plants in Hubei Province in the central China. L

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2

Zhao, Lei, Wen Yang, Yuanle Zhang, Zhanmin Wu, Qiao-Chun Wang, and Yunfeng Wu. "Occurrence and Molecular Variability of Kiwifruit Viruses in Actinidia deliciosa ‘Xuxiang’ in the Shaanxi Province of China." Plant Disease 103, no. 6 (2019): 1309–18. http://dx.doi.org/10.1094/pdis-09-18-1570-re.

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Kiwifruit (Actinidia spp.) is an economically substantial fruit crop with China the main producer. China is the primary source of wild kiwifruit and the largest producer of kiwifruit in terms of both production and planting area, and Shaanxi province is the largest kiwifruit producer in China. Previous studies reported presence of kiwifruit viruses in Actinidia chinensis. In this study, six viruses were identified in kiwifruit ‘Xuxiang’ (A. deliciosa) in Shaanxi, China. The incidence, distribution, and genetic diversity of these viruses were studied. The results showed that Actinidia virus A (

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3

SILALAHI, DARWIN, I. GEDE PUTU WIRAWAN, and MADE SRITAMIN. "Transformasi Genetik Tanaman Kentang (Solanum tuberosum L.) dengan Gen acvB Menggunakan Vektor Agrobacterium tumefaciens." Agrotrop : Journal on Agriculture Science 11, no. 1 (2021): 63. http://dx.doi.org/10.24843/ajoas.2021.v11.i01.p07.

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Agrobacterium tumefaciens Mediated Genetic Transformation of acvB Gene in Potato (Solanum tuberosum L.). Genetic transformations are now routinely applied to plant mediated by Agrobacterium tumefaciens as the most convenient technique. This study aimed to prove the success of A. tumefaciens mediated genetic transformation in potato. A. tumefaciens LBA (pBI 121) and explant of potato shoot were used in this study. Explants were grown in vitro on Murashige and Skoog media. Transformation was implemented using smear technique by smearing A. tumefaciens to injured explant. Experimental groups cons

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4

Coiffier, B., C. Gisselbrecht, R. Herbrecht, H. Tilly, A. Bosly, and N. Brousse. "LNH-84 regimen: a multicenter study of intensive chemotherapy in 737 patients with aggressive malignant lymphoma." Journal of Clinical Oncology 7, no. 8 (1989): 1018–26. http://dx.doi.org/10.1200/jco.1989.7.8.1018.

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From July 1984 to September 1987, 737 patients with aggressive malignant lymphoma (ML) were treated by an intensive regimen (LNH-84) comprising three or four courses of doxorubicin, 75 mg/m2; cyclophosphamide, 1,200 mg/m2; vindesine, 2 mg/m2 x 2; bleomycin, 10 mg x 2; and prednisolone, 60 mg/m2 x 5 (ACVB), consolidation with high-dose methotrexate, ifosfamide, etoposide, asparaginase, and cytarabine, and a randomized late intensification with two courses of cytarabine, cyclophosphamide, teniposide, bleomycin, and prednisone (AraCVmB). Four hundred forty-two patients had intermediate-grade ML,

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5

Luska, G., Ph Hendrickx, A. Kuhl, and P. Lichtlen. "Peripher venöse digitale Subtraktionsangiographie (DSA) zur Kontrolle von aortokoronaren Venenbypassgrafts (ACVB)." RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren 142, no. 01 (1985): 35–40. http://dx.doi.org/10.1055/s-2008-1052596.

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6

Groenewold, Maike K., Stefanie Hebecker, Christiane Fritz, et al. "Virulence ofAgrobacteriumtumefaciensrequires lipid homeostasis mediated by the lysyl-phosphatidylglycerol hydrolase AcvB." Molecular Microbiology 111, no. 1 (2018): 269–86. http://dx.doi.org/10.1111/mmi.14154.

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7

Gede Putu Wirawan, I., and Mineo Kojima. "Distribution of a Chromosomal Virulence Gene,acvB, ofAgrobacterium tumefaciensamong Various Bacteria." Bioscience, Biotechnology, and Biochemistry 60, no. 1 (1996): 50–53. http://dx.doi.org/10.1271/bbb.60.50.

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8

Vinuesa, Pablo, Frauke Neumann-Silkow, Cristina Pacios-Bras, Herman P. Spaink, Esperanza Martínez-Romero, and Dietrich Werner. "Genetic Analysis of a pH-Regulated Operon from Rhizobium tropici CIAT899 Involved in Acid Tolerance and Nodulation Competitiveness." Molecular Plant-Microbe Interactions® 16, no. 2 (2003): 159–68. http://dx.doi.org/10.1094/mpmi.2003.16.2.159.

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Rhizobium tropici CIAT899 is highly acid tolerant and a good competitor for Phaseolus vulgaris nodule occupancy at low pH values. Using Tn5 mutagenesis, we identified an operon required for acid tolerance and nodulation competitiveness. The insertion was mapped to the 5′ end of atvA, encoding a product with high sequence identity to the agrobacterial AcvB virulence protein. Complementation analyses indicated that atvA is an ortholog of acvB, both genes being required for acid tolerance. A Ser/Ala substitution in the LIPASE_SER motif of AtvA resulted in an acid sensitive Fix+ but very poorly co

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9

Goette, A., J. Mittag, A. Friedl, et al. "Möglichkeiten der temporären atrialen Stimulation zur Verhinderung von Vorhofflimmern nach ACVB-OP." Herzschrittmachertherapie und Elektrophysiologie 9, S1 (1998): 99–100. http://dx.doi.org/10.1007/bf03042456.

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10

Neumann, T., W. Ehrlich, J. Sperzel, et al. "Biatriale Stimulation zur Suppression von Vorhofflimmern nach ACVB Operation: Ergebnisse einer prospektiv, randomisierten Untersuchung." Herzschrittmachertherapie und Elektrophysiologie 11, S1 (2000): 91–92. http://dx.doi.org/10.1007/bf03042543.

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11

FUJIWARA, Atushi, Hisao TAKAMURA, Parimal MAJUMDER, Hisashi YOSHIDA, and Mineo KOJIMA. "Functional Analysis of the Protein Encoded by the Chromosomal Virulence Gene(acvB) of Agrobacterium tumefaciens." Japanese Journal of Phytopathology 64, no. 3 (1998): 191–93. http://dx.doi.org/10.3186/jjphytopath.64.191.

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12

Kang, Hi Wan, I. Gede Putu Wirawan, and Mineo Kojima. "Cellular Localization and Functional Analysis of the Protein Encoded by the Chromosomal VirulenceGene(acvB) ofAgrobacterium tumefaciens." Bioscience, Biotechnology, and Biochemistry 58, no. 11 (1994): 2024–32. http://dx.doi.org/10.1271/bbb.58.2024.

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13

Coiffier, B. "Fourteen years of high-dose CHOP (ACVB regimen): Preliminary conclusions about the treatment of aggressive-lymphoma patients." Annals of Oncology 6, no. 3 (1995): 211–17. http://dx.doi.org/10.1093/oxfordjournals.annonc.a059149.

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14

Yamamoto, Y., Y. Kobayashi, Y. Yoshimoto, and K. Okuda. "104 EXPRESSION OF ACTIVIN A AS A LOCAL REGULATOR IN THE BOVINE OVIDUCT." Reproduction, Fertility and Development 27, no. 1 (2015): 145. http://dx.doi.org/10.1071/rdv27n1ab104.

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Activin (ACV) is known as a local regulator of several reproductive functions including follicular development and implantation in mammals. ACVA is a glycopeptide belonging to the transforming growth factor β superfamily, and is a homodimer of inhibin ßA (INHBA) subunits. Follistatin (FST), an ACV-specific binding protein, inhibits ligand-receptor binding. ACV receptor (ACVR) is a hetero-tetramer consisting of 2 kinds of protein, ACVR1 or ACVR1B and ACVR2A or ACVR2B. The oviduct provides an optimal environment for sperm capacitation, fertilization, and early embryonic development. Previous rep

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15

Böckelmann, Irina, Robert Pohl, George Awad, et al. "Stressinduzierte vegetative Antwortreaktion des ärztlichen Personals bei herzchirurgischen Eingriffen." Zentralblatt für Arbeitsmedizin, Arbeitsschutz und Ergonomie 71, no. 5 (2021): 220–33. http://dx.doi.org/10.1007/s40664-021-00436-8.

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Zusammenfassung Hintergrund Chirurgen erleben in ihrem Arbeitsalltag eine hohe psychische Belastung. Die Herzfrequenzvariabilität (HRV) ist als vegetativer Beanspruchungsparameter zur Erfassung von psychischen Belastungen etabliert. Eine geringe HRV ist ein Indikator für hohen Stress. Ziel der Arbeit Ziel der Querschnittsstudie war es, die Aktivierung des autonomen Nervensystems als stressinduzierte Antwortreaktion und das Stressniveau bei chirurgisch tätigen Ärzten verschiedener Qualifikationsstufen während ihrer Tätigkeit anhand der HRV zu untersuchen. Material und Methoden Es wurde die HRV

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16

Kalogeraki, V. S., and S. C. Winans. "The octopine-type Ti plasmid pTiA6 of Agrobacterium tumefaciens contains a gene homologous to the chromosomal virulence gene acvB." Journal of bacteriology 177, no. 4 (1995): 892–97. http://dx.doi.org/10.1128/jb.177.4.892-897.1995.

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17

Winterfeld, H. J., Almuth Risch, H. Siewert, et al. "Der Einfluß der konzentrativen Entspannung auf Blutdruck und Hämodynamik bei hypertonen Patienten mit koronarer Herzkrankheit und aortokoronarer Venenbypassoperation (ACVB)." Physikalische Medizin, Rehabilitationsmedizin, Kurortmedizin 43, no. 04 (1991): 220–24. http://dx.doi.org/10.1055/s-2008-1062184.

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18

Fiedler, C., J. Osterbrink, H. Mayer, and G. C. M. Evers. "Die Inzidenz der akuten postoperativen Verwirrtheit bei kardiochirugischen Patienten nach einem aorto-koronaren-Venenbypass (ACVB) und / oder eines Herzklappenersatzes." intensiv 10, no. 06 (2002): 275–80. http://dx.doi.org/10.1055/s-2002-35448.

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19

Coiffier, B., PA Bryon, M. Ffrench, et al. "Intensive chemotherapy in aggressive lymphomas: updated results of LNH- 80 protocol and prognostic factors affecting response and survival." Blood 70, no. 5 (1987): 1394–99. http://dx.doi.org/10.1182/blood.v70.5.1394.1394.

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Abstract One hundred patients with aggressive malignant lymphomas treated with the LNH-80 regimen were evaluated for long-term survival and pretreatment characteristics predictive of response and survival. LNH- 80 consists of three intensive courses of adriamycin cyclophosphamide vindesine bleomycin (ACVB) followed by sequential consolidation and final intensification. Eighty-four patients went into complete remission (CR), eight had a partial response (PR), three failed to respond, and five died during induction. Twenty-three patients (27%) relapsed, in two of whom a prolonged second remissio

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20

Coiffier, B., PA Bryon, M. Ffrench, et al. "Intensive chemotherapy in aggressive lymphomas: updated results of LNH- 80 protocol and prognostic factors affecting response and survival." Blood 70, no. 5 (1987): 1394–99. http://dx.doi.org/10.1182/blood.v70.5.1394.bloodjournal7051394.

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One hundred patients with aggressive malignant lymphomas treated with the LNH-80 regimen were evaluated for long-term survival and pretreatment characteristics predictive of response and survival. LNH- 80 consists of three intensive courses of adriamycin cyclophosphamide vindesine bleomycin (ACVB) followed by sequential consolidation and final intensification. Eighty-four patients went into complete remission (CR), eight had a partial response (PR), three failed to respond, and five died during induction. Twenty-three patients (27%) relapsed, in two of whom a prolonged second remission was obt

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21

Hirai, Yuka, Noriko Kawabe, Yoshiko Tsuda, Satoru Miyamoto, and Seigo Iwakawa. "Effect of 2-Methoxyestradiol, Buthionine Sulfoximine and Hydrogen Peroxide on the Viability of Renal Carcinoma Cell Lines (ACHN and ACVB)." Biological & Pharmaceutical Bulletin 29, no. 5 (2006): 1064–67. http://dx.doi.org/10.1248/bpb.29.1064.

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22

Dumontet, Charles, Nicolas Mounier, Jean Nicolas Munck, et al. "Factors predictive of early death in patients receiving high-dose CHOP (ACVB regimen) for aggressive non-Hodgkin's lymphoma: a GELA study." British Journal of Haematology 118, no. 1 (2002): 210–17. http://dx.doi.org/10.1046/j.1365-2141.2002.03565.x.

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23

Gede Putu Wirawan, I., and Mineo Kojima. "A Chromosomal Virulence Gene (acvB) Product ofAgrobacterium tumefaciensThat Binds to a T-Strand to Mediate Its Transfer to Host Plant Cells." Bioscience, Biotechnology, and Biochemistry 60, no. 1 (1996): 44–49. http://dx.doi.org/10.1271/bbb.60.44.

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24

Suzutani, Tatsuo, Ken Ishioka, Erik De Clercq, et al. "Differential Mutation Patterns in Thymidine Kinase and DNA Polymerase Genes of Herpes Simplex Virus Type 1 Clones Passaged in the Presence of Acyclovir or Penciclovir." Antimicrobial Agents and Chemotherapy 47, no. 5 (2003): 1707–13. http://dx.doi.org/10.1128/aac.47.5.1707-1713.2003.

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ABSTRACT A total of 21 clones of acyclovir (ACV)-resistant (ACVr) herpes simplex virus type 1 (HSV-1) and 23 clones of penciclovir (PCV)-resistant (PCVr) HSV-1, emerging during serial passages in the presence of ACV or PCV, were isolated under conditions excluding contamination of resistant mutants in the starting virus culture, and their mutations in the thymidine kinase (TK) and DNA polymerase (DNA Pol) genes were analyzed comparatively. Mutations in the TK genes from ACVr mutants consisted of 50% single nucleotide substitutions and 50% frameshift mutations, while the corresponding figures f

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25

MAJUMDER, Parimal, Kenichiro TAKAGI, Hidenari SHIOIRI, Masayuki NOZUE, and Mineo KOJIMA. "Functional Analysis of Two Chromosomal Virulence Genes chvA and acvB of Agrobacterium tumefaciens Using Avirulent Mutants with Transposo 5 Insertion in the Respective Gene." Japanese Journal of Phytopathology 65, no. 3 (1999): 254–63. http://dx.doi.org/10.3186/jjphytopath.65.254.

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26

Duan, Jianmin, Michel Liuzzi, William Paris, et al. "Oral Bioavailability and In Vivo Efficacy of the Helicase-Primase Inhibitor BILS 45 BS against Acyclovir-Resistant Herpes Simplex Virus Type 1." Antimicrobial Agents and Chemotherapy 47, no. 6 (2003): 1798–804. http://dx.doi.org/10.1128/aac.47.6.1798-1804.2003.

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ABSTRACT This study investigated the oral bioavailability and efficacy of BILS 45 BS, a selective herpes simplex virus (HSV) helicase-primase inhibitor, against acyclovir (ACV)-resistant (ACVr) infections mediated by the HSV type 1 (HSV-1) dlsptk and PAAr5 mutant strains. In vitro, the compound was more potent than ACV against wild-type clinical and laboratory HSV-1 strains and ACVr HSV isolates, as determined by a standard plaque reduction assay, with a mean 50% effective concentration of about 0.15 μM. The oral bioavailability of BILS 45 BS in hairless mice was 49%, with a peak concentration

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27

Gonzï¿½lez, Enid T., Darby G. Brown, Jill K. Swanson, and Caitilyn Allen. "Using the Ralstonia solanacearum Tat Secretome To Identify Bacterial Wilt Virulence Factors." Applied and Environmental Microbiology 73, no. 12 (2007): 3779–86. http://dx.doi.org/10.1128/aem.02999-06.

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ABSTRACT To identify secreted virulence factors involved in bacterial wilt disease caused by the phytopathogen Ralstonia solanacearum, we mutated tatC, a key component of the twin-arginine translocation (Tat) secretion system. The R. solanacearum tatC mutation was pleiotropic; its phenotypes included defects in cell division, nitrate utilization, polygalacturonase activity, membrane stability, and growth in plant tissue. Bioinformatic analysis of the R. solanacearum strain GMI1000 genome predicted that this pathogen secretes 70 proteins via the Tat system. The R. solanacearum tatC strain was s

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28

LONG, Alexandra J., Ian J. CLIFTON, Peter L. ROACH, Jack E. BALDWIN, Christopher J. SCHOFIELD, and Peter J. RUTLEDGE. "Structural studies on the reaction of isopenicillin N synthase with the substrate analogue delta-(l-alpha-aminoadipoyl)-l-cysteinyl-d-alpha-aminobutyrate." Biochemical Journal 372, no. 3 (2003): 687–93. http://dx.doi.org/10.1042/bj20021627.

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Isopenicillin N synthase (IPNS) is a non-haem iron(II) oxidase which catalyses the biosynthesis of isopenicillin N from the tripeptide δ-(l-α-aminoadipoyl)-l-cysteinyl-d-valine (ACV). Herein we report crystallographic studies to investigate the reaction of IPNS with the truncated substrate analogue δ-(l-α-aminoadipoyl)-l-cysteinyl-d-α-aminobutyrate (ACAb). It has been reported previously that this analogue gives rise to three β-lactam products when incubated with IPNS: two methyl penams and a cepham. Crystal structures of the IPNS–Fe(II)–ACAb and IPNS–Fe(II)–ACAb–NO complexes have now been sol

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29

Heidenreich, Daniela, Sebastian Kreil, Nadine Mueller, et al. "Topical Treatment of Acyclovir-Resistant Herpes Simplex Virus Stomatitis after Allogeneic Hematopoietic Cell Transplantation." Oncology Research and Treatment 43, no. 12 (2020): 672–78. http://dx.doi.org/10.1159/000510988.

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<b><i>Introduction:</i></b> We report on patients who developed severe acyclovir-resistant (ACVr) herpes simplex virus 1 (HSV-1) stomatitis after allogeneic hematopoietic cell transplantation (HCT). <b><i>Patients:</i></b> HCT patients suffering from HSV-1 stomatitis without response after 1 week of high-dose acyclovir (ACV) were tested for ACV resistance. Patients with proven ACV resistance were treated either topically with cidofovir solution and gel or with topical foscavir cream or with intravenous foscavir. <b><i>Results:</i&g

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30

Knuutila, Aapo, Alex-Mikael Barkoff, Jussi Mertsola, Radim Osicka, Peter Sebo, and Qiushui He. "Simultaneous Determination of Antibodies to Pertussis Toxin and Adenylate Cyclase Toxin Improves Serological Diagnosis of Pertussis." Diagnostics 11, no. 2 (2021): 180. http://dx.doi.org/10.3390/diagnostics11020180.

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Serological diagnosis of pertussis is mainly based on anti-pertussis toxin (PT) IgG antibodies. Since PT is included in all acellular vaccines (ACV), serological assays do not differentiate antibodies induced by ACVs and infection. Adenylate cyclase toxin (ACT) is not included in the ACVs, which makes it a promising candidate for pertussis serology with the specific aim of separating infection- and ACV-induced antibodies. A multiplex lateral flow test with PT and ACT antigens was developed to measure serum antibodies from pertussis-seropositive patients (n = 46), healthy controls (n = 102), an

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31

Bhutta, Maimoona, Oren Shechter, Elisa Gallo, et al. "Ginkgolic Acid Inhibits Herpes Simplex Virus Type 1 Skin Infection and Prevents Zosteriform Spread in Mice." Viruses 13, no. 1 (2021): 86. http://dx.doi.org/10.3390/v13010086.

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Herpes simplex virus type 1 (HSV-1) causes a lifelong latent infection with an estimated global prevalence of 66%. Primary and recurrent HSV infections are characterized by a tingling sensation, followed by an eruption of vesicles, which can cause painful erosions. Commonly used antiviral drugs against HSV infection are nucleoside analogues including acyclovir (ACV), famciclovir, and valacyclovir. Although these nucleoside analogues reduce morbidity and mortality in immunocompetent individuals, ACV-resistant HSV strains (ACVR-HSV) have been isolated from immunocompromised patients. Thus, ACVR-

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Bhutta, Maimoona, Oren Shechter, Elisa Gallo, et al. "Ginkgolic Acid Inhibits Herpes Simplex Virus Type 1 Skin Infection and Prevents Zosteriform Spread in Mice." Viruses 13, no. 1 (2021): 86. http://dx.doi.org/10.3390/v13010086.

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Herpes simplex virus type 1 (HSV-1) causes a lifelong latent infection with an estimated global prevalence of 66%. Primary and recurrent HSV infections are characterized by a tingling sensation, followed by an eruption of vesicles, which can cause painful erosions. Commonly used antiviral drugs against HSV infection are nucleoside analogues including acyclovir (ACV), famciclovir, and valacyclovir. Although these nucleoside analogues reduce morbidity and mortality in immunocompetent individuals, ACV-resistant HSV strains (ACVR-HSV) have been isolated from immunocompromised patients. Thus, ACVR-

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33

Reeve, Wayne G., Lambert Bräu, Joanne Castelli, et al. "The Sinorhizobium medicae WSM419 lpiA gene is transcriptionally activated by FsrR and required to enhance survival in lethal acid conditions." Microbiology 152, no. 10 (2006): 3049–59. http://dx.doi.org/10.1099/mic.0.28764-0.

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Sinorhizobium medicae WR101 was identified as a mutant of WSM419 that contained a minitransposon-induced transcriptional gusA fusion activated at least 20-fold at pH 5.7. The expression of this fusion in moderately acid conditions was dependent on the calcium concentration; increasing the calcium concentration to enhance cell growth and survival in acid conditions decreased the expression of the fusion. A gene region containing the gusA fusion was sequenced, revealing five S. medicae genes: tcsA, tcrA, fsrR, lpiA and acvB. The gusA reporter in WR101 was fused to lpiA, which encodes a putative

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Letsiou, Sophia, Artemis Bakea, Géraldine Le Goff, et al. "Marine Fungus Aspergillus chevalieri TM2-S6 Extract Protects Skin Fibroblasts from Oxidative Stress." Marine Drugs 18, no. 9 (2020): 460. http://dx.doi.org/10.3390/md18090460.

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The strain Aspergillus chevalieri TM2-S6 was isolated from the sponge Axinella and identified according to internal transcribed spacer (ITS) molecular sequence homology with Aspergillus species from the section Restricti. The strain was cultivated 9 days on potato dextrose broth (PDB), and the medium evaluated as antioxidant on primary normal human dermal fibroblasts (NHDF). The cultivation broth was submitted to sterile filtration, lyophilized and used without any further processing to give the Aspergillus chevalieri TM2-S6 cultivation broth ingredient named ACBB. ACCB contains two main compo

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Panteva, M., T. Varadinova, and I. Turel. "Effect of Copper Acyclovir Complexes on Herpes Simplex Virus Type 1 and Type 2 (HSV-1, HSV-2) Infection in Cultured Cells." Metal-Based Drugs 5, no. 1 (1998): 19–23. http://dx.doi.org/10.1155/mbd.1998.19.

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We have found that when copper, zinc or cobalt is bound to a suitable ligand, the appropriate complex exhibited a significant anti-HSV effect (Varadinova et al., 1993; 1996). Recently published data by Sagripanti et al. (1997) also show that the inhibition of HSV by copper was enhanced by reducing agents and that mechanism of the inactivation is similar as for copper-mediated DNA damage (Aruoma, et al. 1991; Dizdaroglu, et al., 1991; Toyokuni and Sagripanti, 1994). Therefore it was interesting to study the efect of Cu(ll) coordination compounds with acyclovir (ACV) on the replication of HSV in

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Martinez Betancur, Octavio, Patricia Quintero Cusguen, and Liliana Mayor Agredo. "Estimación de años de vida ajustados por discapacidad según subtipo de ataque cerebrovascular isquémico agudo." Revista de Salud Pública 18, no. 2 (2016): 226–37. http://dx.doi.org/10.15446/rsap.v18n2.31692.

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<p>Objetivo. Probar la hipótesis que los años de vida ajustados por discapacidad (AVAD) estimados al egreso hospitalario para cada paciente con ataque cerebrovascular (ACV) isquémico agudo, sin terapia de reperfusión, no difieren entre los subtipos etiológicos. Material y Métodos. En el Hospital Universitario de la Samaritana de Bogotá, se seleccionaron para ingreso y seguimiento hasta el egreso, las historias de pacientes con diagnóstico de primer evento de ACV isquémico. El subtipo de ACV isquémico agudo se clasificó mediante los criterios establecidos por el Trial of Org 10172 in Acut

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Takagi, Yuki, Takashi Kojima, Tomoya Nishida, Tomoaki Nakamura, and Kazuo Ichikawa. "Prediction of anterior chamber volume after implantation of posterior chamber phakic intraocular lens." PLOS ONE 15, no. 11 (2020): e0242434. http://dx.doi.org/10.1371/journal.pone.0242434.

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Purpose To predict the anterior chamber volume (ACV) after implantable collamer lens (ICL) implantation based on ICL size and parameters of anterior segment optical coherence tomography (AS-OCT). Design Retrospective study. Methods This study included 222 eyes of 222 patients who underwent ICL implantation at Nagoya Eye Clinic. The patients were divided into two groups: prediction group, for creating the prediction equation (148 eyes, mean age: 32.11 ± 8.04 years), and verification group, for verifying the equation (74 eyes, mean age: 33.03 ± 6.74 years). The angle opening distance (AOD), ante

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Timofeyev, Valeriy, Cliff A. Porter, Dipika Tuteja та ін. "Disruption of adenylyl cyclase type V does not rescue the phenotype of cardiac-specific overexpression of Gαq protein-induced cardiomyopathy". American Journal of Physiology-Heart and Circulatory Physiology 299, № 5 (2010): H1459—H1467. http://dx.doi.org/10.1152/ajpheart.01208.2009.

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Adenylyl cyclase (AC) is the principal effector molecule in the β-adrenergic receptor pathway. ACV and ACVI are the two predominant isoforms in mammalian cardiac myocytes. The disparate roles among AC isoforms in cardiac hypertrophy and progression to heart failure have been under intense investigation. Specifically, the salutary effects resulting from the disruption of ACV have been established in multiple models of cardiomyopathy. It has been proposed that a continual activation of ACV through elevated levels of protein kinase C could play an integral role in mediating a hypertrophic respons

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Sarisky, Robert T., Matthew R. Quail, Philip E. Clark, et al. "Characterization of Herpes Simplex Viruses Selected in Culture for Resistance to Penciclovir or Acyclovir." Journal of Virology 75, no. 4 (2001): 1761–69. http://dx.doi.org/10.1128/jvi.75.4.1761-1769.2001.

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ABSTRACT Penciclovir (PCV), an antiherpesvirus agent in the same class as acyclovir (ACV), is phosphorylated in herpes simplex virus (HSV)-infected cells by the viral thymidine kinase (TK). Resistance to ACV has been mapped to mutations within either the TK or the DNA polymerase gene. An identical activation pathway, the similarity in mode of action, and the invariant cross-resistance of TK-negative mutants argue that the mechanisms of resistance to PCV and ACV are likely to be analogous. A total of 48 HSV type 1 (HSV-1) and HSV-2 isolates were selected after passage in the presence of increas

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Le, Duong Van, Dat Duy Nguyen, and Toan Van Mai. "Investigation of heave dynamics of an air cushion vehicle segment skirt." Science and Technology Development Journal 20, K5 (2017): 23–29. http://dx.doi.org/10.32508/stdj.v20ik5.1154.

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Air Cushion Vehicle (ACV) is a moving vehicle on airbags, which can travel on land and on water to transport people, goods and equipment. An important requirement for ACVs is to: increase reliability and longevity, reduce operating costs, stability and mobility. In this paper, a model for the dynamic behavior of air cushion vehicles segment skirt is presented. In this model, the compressible Bernoulli's equation, Newton's second law of motion are used to predict the dynamic behavior of the air cushion vehicles. Based on the developed model, the heave dynamics parameters of the air cushion vehi

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Thieblemont, Catherine, Bettina Altmann, Olivier Casasnovas, et al. "CNS relapse in DLBCL patients below 60 years treated with R-ACVBP, R-CHOEP, or R-CHOP: A joint analysis of LYSA and GLA/DSHNHL." Journal of Clinical Oncology 39, no. 15_suppl (2021): 7543. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.7543.

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7543 Background: Central nervous system (CNS) relapse occurs in 2-6% of DLBCL patients (pts) increasing to 10% or more in high-risk groups. Intrathecal (IT) or intravenous high-dose methotrexate (HD MTX) have limited if any prophylactic impact on CNS relapse. To address the role of systemic first-line therapy in pts tolerating intensified strategies (R-ACVBP, R-(Mega)CHOEP, R-CHO(E)P), we compared CNS relapses occurring in a large cohort of pts ≤60 years. Methods: We conducted a retrospective analysis including previously untreated pts with DLBCL by central review, age 18-60 years, from multic

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Allison, John L. "Air Cushion Vehicles and Surface Effect Ships for Great Lakes and Great Rivers Transportation." Marine Technology and SNAME News 27, no. 06 (1990): 337–55. http://dx.doi.org/10.5957/mt1.1990.27.6.337.

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A brief introduction to air cushion vehicle (ACV) and surface effect ship (SES) technology is presented, with past and present examples, to show that this technology may now be considered mature. Applicability of ACVs and SESs to transportation on the Great Lakes and rivers of Canada and the U.S. is discussed, with some emphasis on year-round service in the regions affected by ice. An indication of present design capabilities is provided with some examples of application to typical sets of requirements. Future developments are outlined in the light of the rapid expansion of air-supported ferry

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Bhutta, Maimoona, Daniel Sausen, Kirstin Reed, et al. "Peptide Inhibitor of Complement C1, RLS-0071, Reduces Zosteriform Spread of Herpes Simplex Virus Type 1 Skin Infection and Promotes Survival in Infected Mice." Viruses 13, no. 8 (2021): 1422. http://dx.doi.org/10.3390/v13081422.

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Herpes simplex virus type 1 (HSV-1) is a prevalent human pathogen primarily transmitted through skin-to-skin contact, especially on and around mucosal surfaces where there is contact with contaminated saliva during periods of viral shedding. It is estimated that 90% of adults worldwide have HSV-1 antibodies. Cutaneous HSV-1 infections are characterized by a sensation of tingling or numbness at the initial infection site followed by an eruption of vesicles and then painful ulcers with crusting. These symptoms can take ten days to several weeks to heal, leading to significant morbidity. Histolog

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Tabares-Montoya, Daniel Alberto, Stefany Barahona-Giraldo, Lucy Ramírez-Reyes, and Olga Alicia Nieto-Cárdenas. "ACCIDENTE CEREBROVASCULAR Y FIBRILACIÓN AURICULAR EN UNA INSTITUCIÓN PRESTADORA DE SALUD DEL QUINDÍO." Revista de Investigaciones Universidad del Quindío 33, no. 1 (2021): 115–25. http://dx.doi.org/10.33975/riuq.vol33n1.458.

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Introducción: La Fibrilación Auricular (FA) se ha relacionado frecuentemente con el Accidente Cerebrovascular (ACV). Objetivo: Describir la prevalencia de FA y sus comorbilidades en pacientes de un programa de Riesgo Cardiovascular de una Institución Prestadora de Servicios de Salud (IPS) del Quindío. Material y método: Estudio descriptivo de corte transversal. Se accedió a las historias clínicas de 193 pacientes con diagnóstico de FA, con consentimiento institucional. Se obtuvo una muestra de 53 sujetos de estudio, calculada para población finita, ajustada por prevalencia, aleatorizada, con r

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Odeh, Fadi, and Nijad Al-Najdawi. "ACNB." International Journal of Information Technology and Web Engineering 8, no. 1 (2013): 23–35. http://dx.doi.org/10.4018/jitwe.2013010102.

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Integrating association rule discovery and classification in data mining brings a new approach known as associative classification. Associative classification is a promising approach that often constructs more accurate classification models (classifiers) than the traditional classification approaches such as decision trees and rule induction. In this research, the authors investigate the use of associative classification on the high dimensional data in text categorization. This research focuses on prediction, a very important step in classification, and introduces a new prediction method calle

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Markey, Kevin, Catpagavalli Asokanathan, and Ian Feavers. "Assays for Determining Pertussis Toxin Activity in Acellular Pertussis Vaccines." Toxins 11, no. 7 (2019): 417. http://dx.doi.org/10.3390/toxins11070417.

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Whooping cough is caused by the bacterium Bordetella pertussis. There are currently two types of vaccines that can prevent the disease; whole cell vaccines (WCV) and acellular vaccines (ACV). The main virulence factor produced by the organism is pertussis toxin (PTx). This toxin is responsible for many physiological effects on the host, but it is also immunogenic and in its detoxified form is the main component of all ACVs. In producing toxoid for vaccines, it is vital to achieve a balance between sufficiently detoxifying PTx to render it safe while maintaining enough molecular structure that

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Tegenbos, Guy. "Sociale verkiezingen 1987 : Kaderleden verzwakken traditionele vakbonden." Res Publica 30, no. 2-3 (1988): 299–310. http://dx.doi.org/10.21825/rp.v30i2-3.18901.

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In 1987 the centre-right coalition was able to break through partially the triopoly of the three trade unions - the christian ACV, the socialist ABVV en the liberal ACLVB - by admitting to the four-yearly social elections separate lists of candidates for the members of the executive staffs.As a result of this, the position of the three unions weakened. The decline was most strongly felt by the ABVV; the socialist union lost 2.6 %. The minor loss of 0.7 % enabled the christian ACV to regain its position as the strongest Belgian union, a position which was taken for the first time in 1979 and wa

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Thieblemont, C., D. Antal, L. Lacotte-Thierry, et al. "Rituximab/Chemotherapy Induction Treatment Followed by High-Dose Therapy and Autologous Transplantation in Patients with Mantle Cell Lymphoma." Blood 104, no. 11 (2004): 1389. http://dx.doi.org/10.1182/blood.v104.11.1389.1389.

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Abstract Between September 1998 and September 2003, 25 patients with Mantle Cell Lymphoma (MCL) were treated in our centres with a treatment combining rituximab + chemotherapy at induction with subsequent consolidation high-dose chemo/radiotherapy (HDT) and autologous PBSC-transplantation. Twenty-two (80%) patients received this treatment in first line therapy. Median age of patients was 53 (range: 41–65). All patients had a disseminated disease with a bone marrow (BM) involvement in 23 (92%) patients. Elevated LDH was present in 11 patients. All patients except one had a good performance stat

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McElgunn, Peggy. "ACVP Update." Cardiac Cath Lab Director 1, no. 1 (2011): 46. http://dx.doi.org/10.1177/2150133510395714.

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Krämer-Hoppe, Rike. "ACAB = Beleidigung?" JURA - Juristische Ausbildung 40, no. 6 (2018): 621–30. http://dx.doi.org/10.1515/jura-2018-0128.

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