Literatura académica sobre el tema "Amoeboid motility"

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Artículos de revistas sobre el tema "Amoeboid motility"

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Leo, Angela, Erica Pranzini, Laura Pietrovito, et al. "Claisened Hexafluoro Inhibits Metastatic Spreading of Amoeboid Melanoma Cells." Cancers 13, no. 14 (2021): 3551. http://dx.doi.org/10.3390/cancers13143551.

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Metastatic melanoma is characterized by poor prognosis and a low free-survival rate. Thanks to their high plasticity, melanoma cells are able to migrate exploiting different cell motility strategies, such as the rounded/amoeboid-type motility and the elongated/mesenchymal-type motility. In particular, the amoeboid motility strongly contributes to the dissemination of highly invasive melanoma cells and no treatment targeting this process is currently available for clinical application. Here, we tested Claisened Hexafluoro as a novel inhibitor of the amoeboid motility. Reported data demonstrate
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Pietrovito, Laura, Giuseppina Comito, Matteo Parri, Elisa Giannoni, Paola Chiarugi, and Maria Letizia Taddei. "Zoledronic Acid Inhibits the RhoA-mediated Amoeboid Motility of Prostate Cancer Cells." Current Cancer Drug Targets 19, no. 10 (2019): 807–16. http://dx.doi.org/10.2174/1568009619666190115142858.

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Background:The bisphosphonate Zoledronic acid (ZA) is a potent osteoclast inhibitor currently used in the clinic to reduce osteoporosis and cancer-induced osteolysis. Moreover, ZA exerts an anti-tumor effect in several tumors. Despite this evidence, the relevance of ZA in prostate cancer (PCa) is not completely understood.Objective:To investigate the effect of ZA administration on the invasive properties of PC3 cells, which are characterised by RhoA-dependent amoeboid motility.Methods:The effect of ZA administration on the in vitro invasive properties of PC3 cells was evaluated by cell migrati
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Klemm, Lucas C., Ryan A. Denu, Laurel E. Hind, Briana L. Rocha-Gregg, Mark E. Burkard, and Anna Huttenlocher. "Centriole and Golgi microtubule nucleation are dispensable for the migration of human neutrophil-like cells." Molecular Biology of the Cell 32, no. 17 (2021): 1545–56. http://dx.doi.org/10.1091/mbc.e21-02-0060.

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Callan-Jones, A. C., and R. Voituriez. "Active gel model of amoeboid cell motility." New Journal of Physics 15, no. 2 (2013): 025022. http://dx.doi.org/10.1088/1367-2630/15/2/025022.

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Peretz-Soroka, Hagit, Reuven Tirosh, Jolly Hipolito, et al. "A bioenergetic mechanism for amoeboid-like cell motility profiles tested in a microfluidic electrotaxis assay." Integrative Biology 9, no. 11 (2017): 844–56. http://dx.doi.org/10.1039/c7ib00086c.

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Dalal, Swapnil, Alexander Farutin, and Chaouqi Misbah. "Amoeboid swimming in a compliant channel." Soft Matter 16, no. 6 (2020): 1599–613. http://dx.doi.org/10.1039/c9sm01689a.

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We studied influence of elasticity of surrounding environment on cell motility by numerically investigating effects of wall flexibility and channel confinement on flow dynamics of amoeboid swimming in compliant channel.
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Saito, Koji, Yuta Ozawa, Keisuke Hibino, and Yasutaka Ohta. "FilGAP, a Rho/Rho-associated protein kinase–regulated GTPase-activating protein for Rac, controls tumor cell migration." Molecular Biology of the Cell 23, no. 24 (2012): 4739–50. http://dx.doi.org/10.1091/mbc.e12-04-0310.

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Tumor cells exhibit two interconvertible modes of cell motility referred to as mesenchymal and amoeboid migration. Mesenchymal mode is characterized by elongated morphology that requires high GTPase Rac activation, whereas amoeboid mode is dependent on actomyosin contractility induced by Rho/Rho-associated protein kinase (ROCK) signaling. While elongated morphology is driven by Rac-induced protrusion at the leading edge, how Rho/ROCK signaling controls amoeboid movement is not well understood. We identified FilGAP, a Rac GTPase-activating protein (GAP), as a mediator of Rho/ROCK-dependent amoe
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Copos, Calina A., Robert D. Guy, Sam Walcott, Juan Carlos del Alamo, and Alex Mogilner. "Mechanosensitive Adhesion Explains Stepping Motility in Amoeboid Cells." Biophysical Journal 112, no. 3 (2017): 433a. http://dx.doi.org/10.1016/j.bpj.2016.11.2315.

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Bullock, Timothy L., Airlie J. McCoy, Helen M. Kent, Thomas M. Roberts, and Murray Stewart. "Structural basis for amoeboid motility in nematode sperm." Nature Structural Biology 5, no. 3 (1998): 184–89. http://dx.doi.org/10.1038/nsb0398-184.

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Copos, Calina A., Sam Walcott, Juan C. del Álamo, Effie Bastounis, Alex Mogilner, and Robert D. Guy. "Mechanosensitive Adhesion Explains Stepping Motility in Amoeboid Cells." Biophysical Journal 112, no. 12 (2017): 2672–82. http://dx.doi.org/10.1016/j.bpj.2017.04.033.

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Tesis sobre el tema "Amoeboid motility"

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Zanchi, Roberto. "The involvement of the endocytic cycle in amoeboid cell motility." Thesis, University of Cambridge, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.608458.

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Leo, Angela. "The study of cell motility and plasticity in cancer: the role of the crosstalk between BM-MSCs and tumor in osteosarcoma progression and Claisened Hexafluoro as potential inhibitor of amoeboid motility in metastatic melanoma." Doctoral thesis, Università di Siena, 2021. http://hdl.handle.net/11365/1128636.

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Part 1 Growing evidence suggest that bone marrow-derived mesenchymal stem cells (BM-MSCs) are key players in tumor stroma. Here, we investigated the cross-talk between BM-MSCs and osteosarcoma (OS) cells in tumor progression. We revealed a strong tropism of BM-MSCs towards these tumor cells and identified monocyte chemoattractant protein (MCP)-1, growth-regulated oncogene (GRO)-α and transforming growth factor (TGF)-β1 as pivotal factors for BM-MSC chemotaxis. Once in contact with OS cells, BM-MSCs trans-differentiate into cancer-associated fibroblasts, further increasing MCP-1, GRO-α, inter
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Lewis, Owen Leslie. "Mathematical Investigation of Hydrodynamic Contributions to Amoeboid Cell Motility in Physarum polycephalum." Thesis, University of California, Davis, 2015. http://pqdtopen.proquest.com/#viewpdf?dispub=3685252.

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<p> In this work, we investigate the role of intracellular fluid flow in the migration of <i>Physarum polycephalum</i>. We develop two distinct models. Initially, we model the intracellular space of a <i>physarum </i> plasmodium as a peristaltic chamber. We derive a PDE relating the deformation of the chamber boundary and the flux of fluid along the chamber center line. We then solve this PDE for two distinct boundary deformations and evaluate the characteristic stress associated with the peristaltic flow. We compare the derived stress, as well as the relative phase of the deformation and flow
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Ingram, Mark Edward. "Whole Skin Locomotion Inspired by Amoeboid Motility Mechanisms: Mechanics of the Concentric Solid Tube Model." Thesis, Virginia Tech, 2006. http://hdl.handle.net/10919/35100.

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As the technology of robotics intelligence advances, and new application areas for mobile robots increase, the need for alternative fundamental locomotion mechanisms for robots that allow them to maneuver into complex unstructured terrain becomes critical. In this research we present a novel locomotion mechanism for mobile robots inspired by the motility mechanism of certain single celled organisms such as amoebae. Whole Skin Locomotion (WSL), as we call it, works by way of an elongated toroid which turns itself inside out in a single continuous motion, effectively generating the overall mot
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D'Alessandro, Joseph. "Collective regulation of the amoeboid motility : the role of short and long-range interactions in vegetative Dictyostelium discoideum." Thesis, Lyon, 2016. http://www.theses.fr/2016LYSE1039/document.

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La motilité cellulaire est fondamentale dans de nombreux processus physiologiques, qu’ils soient normaux ou pathologiques. Cependant, bien que ces derniers impliquent la plupart du temps de nombreuses cellules se mouvant en même temps, les effets des interactions entre cellules sur leur dynamique, à la fois individuelle et collective, restent assez mal connu. Dans cette thèse, j’ai utilisé Dictyostelium discoideum à l’état végétatif pour étudier cette régulation collective de la motilité. Je me suis principalement appuyé sur une analyse minutieuse de nombreuses trajectoires cellulaires dans de
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Wyse, Meghan M. "CXCL12 Mediated Regulation of the Cytoskeletal Regulator mDia2 Formin Induces Amoeboid Conversions and Cellular Plasticity in Migrating Human Breast Carcinoma Cells." University of Toledo / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1404042854.

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Kulawiak, Dirk Alexander [Verfasser], Harald [Akademischer Betreuer] Engel, Harald [Gutachter] Engel, Markus [Gutachter] Bär, and Carsten [Gutachter] Beta. "Physical minimal models of amoeboid cell motility / Dirk Alexander Kulawiak ; Gutachter: Harald Engel, Markus Bär, Carsten Beta ; Betreuer: Harald Engel." Berlin : Technische Universität Berlin, 2017. http://d-nb.info/1156010403/34.

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Nègre, Paulin. "Mécanismes de motilité et guidage sous flux des leucocytes humains." Thesis, Aix-Marseille, 2018. http://www.theses.fr/2018AIXM0747/document.

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La capacité des leucocytes à se déplacer dans tout l’organisme est indispensable pour une réponse immunitaire rapide et efficace. Leur migration, dite amiboïde, est caractérisée par une vitesse importante (10-20 μm/min) et une grande adaptabilité face aux divers environnements qu’ils rencontrent, qu’ils soient bidimensionnels comme la paroi luminale endothéliale ou tridimensionnels (3D) comme les tissus. Telle qu'actuellement décrite, la migration amiboïde requiert de l’adhésion ou de la friction avec un support solide. Nous avons ici montré que les lymphocytes T effecteurs sont capables de na
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Buttery, Shawnna Marie Roberts Thomas M. "Characterization of the cytosolic proteins involved in the amoeboid motility of ascaris sperm." 2003. http://etd.lib.fsu.edu/theses/available/etd-08192004-100416.

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Thesis (Ph. D.)--Florida State University, 2003.<br>Advisor: Dr. Thomas M. Roberts, Florida State University, College of Arts and Sciences, Department of Biological Science. Title and description from dissertation home page (viewed Aug. 23, 2004). Includes bibliographical references.
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Capítulos de libros sobre el tema "Amoeboid motility"

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Shimmen, T. "Mechanisms of Cytoplasmic Streaming and Amoeboid Movement." In Muscle Contraction and Cell Motility. Springer Berlin Heidelberg, 1992. http://dx.doi.org/10.1007/978-3-642-76927-6_6.

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Italiano, Joseph E., Murray Stewart, and Thomas M. Roberts. "How the assembly dynamics of the nematode major sperm protein generate amoeboid cell motility." In International Review of Cytology. Elsevier, 2001. http://dx.doi.org/10.1016/s0074-7696(01)02002-2.

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Fukui, Yoshio. "Toward a New Concept of Cell Motility: Cytoskeletal Dynamics in Amoeboid Movement and Cell Division." In International Review of Cytology. Elsevier, 1993. http://dx.doi.org/10.1016/s0074-7696(08)61514-4.

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Maynard Smith, John, and Eors Szathmary. "The origin of eukaryotes." In The Major Transitions in Evolution. Oxford University Press, 1997. http://dx.doi.org/10.1093/oso/9780198502944.003.0012.

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The basic structures of a bacterial and a eukaryotic cell are shown in Fig. 8.1. The differences whose origins call for an explanation are as follows: • The bacterial cell has a rigid outer cell wall, usually made of the peptidoglycan, murein. In eukaryotes, the rigid cell wall is not universal, and cell shape is maintained primarily by an internal cytoskeleton of filaments and microtubules. • Eukaryotic cells have a complex system of internal membranes, including the nuclear envelope, endoplasmic reticulum and lysosomes. • Bacteria have a single circular chromosome, attached to the rigid outer cell wall. In eukaryotes, linear chromosomes are contained within a nuclear envelope, which separates transcription from translation: communication between nucleus and cytoplasm is via pores in the nuclear envelope. • Eukaryotes have a complex cytoskeleton. The actomyosin system powers cell division, phagocytosis, amoeboid motion and the overall contractility to resist osmotic swelling. Microtubules and the associated motor proteins (kinesin, dynein and dynamin) ensure the accurate segregation of chromosomes in mitosis, ciliary motility and the movement of transport vesicles. Intermediate filaments form the structural basis for the association of the endomembranes and nuclear-pore complexes with the chromatin to form the nuclear envelope, while other intermediate filaments help to anchor the nucleus in the cytoplasm. One crucial difference between prokaryotes and most eukaryotes has been omitted from Fig. 8.1: this is the presence of mitochondria, and, in plants and algae, of chloroplasts. The reason for the omission is that, on the scenario for eukaryote origins that seems to us most plausible, these intracellular organelles originated later in time than the structures shown in the figure. The differences between these cell types justifies the recognition of two empires of life (above the kingdom level): Bacteria and Eukaryota (Cavalier-Smith, 199la; Table 8.1). (It is interesting that this taxonomic rank was recognized by Linnaeus.) Within each of the empires, there are two major categories: Bacteria consist of the kingdoms Eubacteria and Archaebacteria, and Eukaryota are divided into the superkingdoms Archaezoa and Metakaryota. The justification for these divisions is as follows. The Archaebacteria, in contrast to the Eubacteria, never have murein cell walls, and their single cell membrane contains isoprenoidal ether rather than acyl ester lipids.
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Actas de conferencias sobre el tema "Amoeboid motility"

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Xiong, Yuan, and Pablo A. Iglesias. "Automated characterization of amoeboid motility." In 2009 43rd Annual Conference on Information Sciences and Systems (CISS). IEEE, 2009. http://dx.doi.org/10.1109/ciss.2009.5054747.

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Ingram, Mark, and Dennis Hong. "Whole Skin Locomotion Inspired by Amoeboid Motility Mechanisms." In ASME 2005 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. ASMEDC, 2005. http://dx.doi.org/10.1115/detc2005-85419.

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In this paper, we present a novel locomotion mechanism for mobile robots inspired by the motility mechanisms of single celled organisms that use cytoplasmic streaming to generate pseudopods for locomotion. The Whole Skin Locomotion, as we call it, works by way of an elongated toroid which turns itself inside out in a single continuous motion, effectively generating the overall motion of the cytoplasmic streaming ectoplasmic tube in amoebae. With an elastic membrane or a mesh of links acting as its outer skin, the robot can easily squeeze between obstacles or under a collapsed ceiling and move
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Wyse, Meghan M., Andrea L. Nestor-Kalinoski, and Kathryn M. Eisenmann. "Abstract C50: CXCL12-triggered amoeboid cell motility is mediated through a RhoA-directed signaling hub." In Abstracts: AACR Special Conference on Tumor Invasion and Metastasis - January 20-23, 2013; San Diego, CA. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.tim2013-c50.

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Eisenmann, Kathryn. "Abstract LB-270: Regulation of the cortical actin cytoskeleton and amoeboid motility through the mDia2 formin;DIP complex." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-lb-270.

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Mohamed, Islam, Ahmed Moahmed, Mennatallah Abdelkader, Alaaeldin Saleh, and Ala-Eddin Al-Moustafa. "Elaeagnus Angustifolia: a Promising Medicinal Plant for Cancer Theraby." In Qatar University Annual Research Forum & Exhibition. Qatar University Press, 2020. http://dx.doi.org/10.29117/quarfe.2020.0124.

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Introduction: Elaeagnus angustifolia (EA) is a medicinal plant that has been used for centuries in treating many human diseases, in the Middle East, including fever, amoebic dysentery, gastrointestinal problems. However, the effect of EA plant extract on human cancer progression especially oral malignancy has not been investigated yet. Thus, first we examined the effect of EA flower extract on angiogenesis in ovo, and on selected parameters in human oral cancer cells. Materials and methods: Chorioallantoic membranes (CAMs) of chicken embryos at 3-7 days of incubation were used to assess the ef
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