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Artículos de revistas sobre el tema "Articular cartilage"

Autor: Grafiati

Publicado: 4 de junio de 2021

Última modificación: 25 de julio de 2025

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1

Wardale, R. J., and V. C. Duance. "Quantification and immunolocalisation of porcine articular and growth plate cartilage collagens." Journal of Cell Science 105, no. 4 (1993): 975–84. http://dx.doi.org/10.1242/jcs.105.4.975.

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The collagens of growth plate and articular cartilage from 5–6 month old commercial pigs were characterised. Growth plate cartilage was found to contain less total collagen than articular cartilage as a proportion of the dry weight. Collagen types I, II, VI, IX and XI are present in both growth plate and articular cartilage whereas type X is found exclusively in growth plate cartilage. Types III and V collagen could not be detected in either cartilage. Type I collagen makes up at least 10% of the collagenous component of both cartilages. There are significant differences in the ratios of the q

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2

Wardale, R. J., and V. C. Duance. "Characterisation of articular and growth plate cartilage collagens in porcine osteochondrosis." Journal of Cell Science 107, no. 1 (1994): 47–59. http://dx.doi.org/10.1242/jcs.107.1.47.

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The articular and growth plate cartilages of osteochondrotic pigs were examined and compared with those from clinically normal animals. Both types of osteochondrotic cartilage showed considerable localised thickening apparently due to a lack of ossification. Histological examination of cartilage lesions demonstrated a breakdown in the normal pattern of chondrocyte maturation. Articular cartilage lesions lacked mature clones of chondrocytes in the calcifying region. Growth plate cartilage showed an accumulation of disorganised hypertrophic chondrocytes rather than the well-defined columns seen

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3

Gong, Huchen, Yutao Men, Xiuping Yang, Xiaoming Li, and Chunqiu Zhang. "Experimental Study on Creep Characteristics of Microdefect Articular Cartilages in the Damaged Early Stage." Journal of Healthcare Engineering 2019 (November 13, 2019): 1–9. http://dx.doi.org/10.1155/2019/8526436.

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Traumatic joint injury is known to cause cartilage deterioration and osteoarthritis. In order to study the mechanical mechanism of damage evolution on articular cartilage, taking the fresh porcine articular cartilage as the experimental samples, the creep experiments of the intact cartilages and the cartilages with different depth defect were carried out by using the noncontact digital image correlation technology. And then, the creep constitutive equations of cartilages were established. The results showed that the creep curves of different layers changed exponentially and were not coincident

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4

Wansin, Yew, Mohd Juzaila Abd Latif Yew, Sharifah Majedah Idrus Alhabshi, Amaluddin Mahmud, and Mohammed Rafiq Abdul Kadri. "Correlation of Biomechanical Properties and Grayscale of Articular Cartilage using Low-Field Magnetic Resonance Imaging." International Journal of Engineering & Technology 7, no. 4.26 (2018): 1–5. http://dx.doi.org/10.14419/ijet.v7i4.26.22128.

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Osteoarthritis is a joint disease that caused by the progression of degenerative articular cartilage tissue. The degeneration of the articular cartilage resulted in alteration of the biomechanical properties. Magnetic resonance imaging (MRI) has become the most potential imaging technique to assess the condition of the articular cartilage. However, most of the previous studies of articular cartilage were performed using high-field MRI units. Therefore, this study aimed to examine the correlation between the biomechanical properties of articular cartilage and the image grayscale using low-field

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5

Chetina, E. V., and E. V. Chetina. "Inhibition of activity of collagen degradation in cartilage of patients with osteoarthrosis byactivation of glycolysis." Osteoporosis and Bone Diseases 14, no. 1 (2011): 8–12. http://dx.doi.org/10.14341/osteo201118-12.

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Aim. To study the effect of glycolysis activators deferrioxamine (DFO), CoCl2, V(SO4)2 and mimosine on collagen cleavage activity by collagenase in osteoarthritic (OA) articular cartilage explants. Materials and methods. 32 OA articular cartilages obtained after arthroplasty were examined in the study. Cartilages were cultured in the presence of 10-50μM DFO, CoCl2, V(SO4)2 or mimosine. Collagen cleavage activity was measured by ELISA. Inhibition of protein or DNA synthesis in the presence of [3H]-labeled proline or thymidine, respectively, was used for evaluation of examined agent toxicity. Re

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6

Li, Yefu, and Lin Xu. "Advances in understanding cartilage remodeling." F1000Research 4 (August 28, 2015): 642. http://dx.doi.org/10.12688/f1000research.6514.1.

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Cartilage remodeling is currently among the most popular topics in osteoarthritis research. Remodeling includes removal of the existing cartilage and replacement by neo-cartilage. As a loss of balance between removal and replacement of articular cartilage develops (particularly, the rate of removal surpasses the rate of replacement), joints will begin to degrade. In the last few years, significant progress in molecular understanding of the cartilage remodeling process has been made. In this brief review, we focus on the discussion of some current “controversial” observations in articular carti

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7

Hayes, Anthony J., John Whitelock, and James Melrose. "Regulation of FGF-2, FGF-18 and Transcription Factor Activity by Perlecan in the Maturational Development of Transitional Rudiment and Growth Plate Cartilages and in the Maintenance of Permanent Cartilage Homeostasis." International Journal of Molecular Sciences 23, no. 4 (2022): 1934. http://dx.doi.org/10.3390/ijms23041934.

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The aim of this study was to highlight the roles of perlecan in the regulation of the development of the rudiment developmental cartilages and growth plate cartilages, and also to show how perlecan maintains permanent articular cartilage homeostasis. Cartilage rudiments are transient developmental templates containing chondroprogenitor cells that undergo proliferation, matrix deposition, and hypertrophic differentiation. Growth plate cartilage also undergoes similar changes leading to endochondral bone formation, whereas permanent cartilage is maintained as an articular structure and does not

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8

Sharifi, Ali Mohammad, Ali Moshiri, and Ahmad Oryan. "Articular cartilage." Current Orthopaedic Practice 27, no. 6 (2016): 644–65. http://dx.doi.org/10.1097/bco.0000000000000425.

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9

Hayes, Donald W., Randall L. Brower, and Kelly J. John. "Articular Cartilage." Clinics in Podiatric Medicine and Surgery 18, no. 1 (2001): 35–53. http://dx.doi.org/10.1016/s0891-8422(23)01166-7.

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10

McCarty, Eric C. "Articular Cartilage." Clinics in Sports Medicine 36, no. 3 (2017): i. http://dx.doi.org/10.1016/s0278-5919(17)30039-x.

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11

Rodkey, William G. "Articular cartilage." Journal of Equine Veterinary Science 17, no. 2 (1997): 80. http://dx.doi.org/10.1016/s0737-0806(97)80334-6.

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12

Miller, Mark D. "Articular Cartilage." Clinics in Sports Medicine 36, no. 3 (2017): xiii—xiv. http://dx.doi.org/10.1016/j.csm.2017.04.002.

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13

Gradisar, Ivan A., and James A. Porterfield. "Articular cartilage." Topics in Geriatric Rehabilitation 4, no. 3 (1989): 1–9. http://dx.doi.org/10.1097/00013614-198904000-00004.

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14

Lees, Deborah, and Paul Partington. "Articular cartilage." Orthopaedics and Trauma 30, no. 3 (2016): 265–72. http://dx.doi.org/10.1016/j.mporth.2016.04.007.

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15

Simon, Timothy M., and Douglas W. Jackson. "Articular Cartilage." Sports Medicine and Arthroscopy Review 26, no. 1 (2018): 31–39. http://dx.doi.org/10.1097/jsa.0000000000000182.

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16

Lychagin, A. V., S. V. Ivannikov, V. I. Yusupov, et al. "Laser treatment of chondromalacia lesions in the articular cartilage." Laser Medicine 25, no. 4 (2022): 9–15. http://dx.doi.org/10.37895/2071-8004-2021-25-4-9-15.

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Objective: to select optimal parameters of two-wave near-infrared laser irradiation for the arthroscopic treatment of chondromalacia foci in the articular cartilage. Material and methods. Bull articular cartilages were treated with laser light delivered by a fifi ber and having various parameters. Human articular cartilages with chondromalacia foci taken during the total knee replacement were also treated with laser light delivered by a fifi ber and having various parameters. The processed cartilage samples were examined macroscopically and then histologically. Changes in the structure of ar[1

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17

Poole, A. R., C. Webber, I. Pidoux, H. Choi, and L. C. Rosenberg. "Localization of a dermatan sulfate proteoglycan (DS-PGII) in cartilage and the presence of an immunologically related species in other tissues." Journal of Histochemistry & Cytochemistry 34, no. 5 (1986): 619–25. http://dx.doi.org/10.1177/34.5.3701029.

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A monoclonal antibody to a core-protein-related epitope of a small dermatan sulfate-rich proteoglycan (DS-PGII) isolated from adult bovine articular cartilage (22) was used to localize this molecule, or molecules containing this epitope, in bovine articular cartilages, in cartilage growth plate, and in other connective tissues. Using an indirect method employing peroxidase-labeled pig anti-mouse immunoglobulin G, DS-PGII was shown to be present mainly in the superficial zone of adult articular condylar cartilage of the metacarpal-phalangeal joint. In fetal articular and epiphyseal cartilages,

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18

Pordzik, Johannes, Anke Bernstein, Julius Watrinet, et al. "Correlation of Biomechanical Alterations under Gonarthritis between Overlying Menisci and Articular Cartilage." Applied Sciences 10, no. 23 (2020): 8673. http://dx.doi.org/10.3390/app10238673.

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Just like menisci, articular cartilage is exposed to constant and varying stresses. Injuries to the meniscus are associated with the development of gonarthritis. Both the articular cartilage and the menisci are subject to structural changes under gonarthritis. The aim of this study was to investigate biomechanical alterations in articular cartilage and the menisci under gonarthritis by applying an indentation method. The study assessed 11 menisci from body donors as controls and 21 menisci from patients with severe gonarthritis. For the simultaneous examination of the articular cartilage and t

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19

Khajehsaeid, Hesam, Zanko Abdollahpour, and Hedyeh Farahmandpour. "Effect of Degradation and Osteoarthritis on the Viscoelastic Properties of Human Knee Articular Cartilage: An Experimental Study and Constitutive Modeling." Biomechanics 1, no. 2 (2021): 225–38. http://dx.doi.org/10.3390/biomechanics1020019.

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Articular cartilage, as a hydrated soft tissue which covers diarthrodial joints, has a pivotal role in the musculoskeletal system. Osteoarthritis is the most common degenerative disease that affects most individuals over the age of 55. This disease affects the elasticity, lubrication mechanism, damping function, and energy absorption capability of articular cartilage. In order to investigate the effect of osteoarthritis on the performance of articular cartilage, the mechanical behavior of human knee articular cartilage was experimentally investigated. Progressive cyclic deformation was applied

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20

Clark, Andrea L., Linda Mills, David A. Hart, and Walter Herzog. "MUSCLE-INDUCED PATELLOFEMORAL JOINT LOADING RAPIDLY AFFECTS CARTILAGE mRNA LEVELS IN A SITE SPECIFIC MANNER." Journal of Musculoskeletal Research 08, no. 01 (2004): 1–12. http://dx.doi.org/10.1142/s0218957704001223.

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Mechanical loading of articular cartilage affects the synthesis and degradation of matrix macromolecules. Much of the work in this area has involved mechanical loading of articular cartilage explants or cells in vitro and assessing biological responses at the mRNA and protein levels. In this study, we developed a new experimental technique to load an intact patellofemoral joint in vivo using muscle stimulation. The articular cartilages were cyclically loaded for one hour in a repeatable and measurable manner. Cartilage was harvested from central and peripheral regions of the femoral groove and

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21

Horky, D., and F. Tichy. "Submicroscopic structure of canine articular cartilage." Veterinární Medicína 49, No. 6 (2012): 207–16. http://dx.doi.org/10.17221/5697-vetmed.

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Canine articular cartilage was studied in male dogs at age 1, 4, 5 and 8 years. Samples collected from four hip joints and two humeral joints in each age category were processed by standard methods to be examined by scanning and transmission electron microscopy. The cartilage of both joints was similar in structure. In the superficial cartilage layer of one-year-old animals, individual spindle-shaped chondrocytes in the extracellular matrix were, together with associated collagen fibrils, located parallel to the surface. When viewed by scanning electron microscopy, they were distinctly promine

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22

Müller, Andreas, and Friedrich P. Paulsen. "Impact of Vocal Cord Paralysis on Cricoarytenoid Joint." Annals of Otology, Rhinology & Laryngology 111, no. 10 (2002): 896–901. http://dx.doi.org/10.1177/000348940211101006.

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To demonstrate structural changes in the cricoarytenoid joint after recurrent laryngeal nerve paralysis, we performed a laboratory investigation of fixed arytenoid cartilages from adult humans obtained during laser surgical arytenoidectomy in cases of bilateral vocal fold paralysis, analyzing the articular cartilage, the joint capsule, and the attached laryngeal musculature. Ten arytenoid cartilages from adult humans were studied by means of histology, as well as scanning and transmission electron microscopy. After long-standing denervation (>6 months), all arytenoid cartilages showed degen

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23

Amaratunga, H. A., S. B. Adikari, H. J. Suraweera, et al. "Histopathological changes due to osteoarthritis in articular cartilages of the knee." Sri Lanka Anatomy Journal 6, no. 2 (2022): 22–33. http://dx.doi.org/10.4038/slaj.v6i2.162.

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Introduction: The bony ends of a synovial joint are lined by a specialised hyaline cartilage termed the articular cartilage. Articular cartilage can be affected with degenerative diseases such as osteoarthritis. Knee being one of the larger joints built for weight bearing is the commonest site for osteoarthritis. The aim of this study was to describe the macroscopic and microscopic features of articular cartilages of the knee joint in patients diagnosed with primary osteoarthritis.Methods: Seventy-two articular cartilages removed during total knee replacement surgery were observed for macrosco

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24

Tarniţă, Daniela, Marius Catana, and Dan Nicolae Tarnita. "Modeling and Finite Element Analysis of the Human Knee Joint Affected by Osteoarthritis." Key Engineering Materials 601 (March 2014): 147–50. http://dx.doi.org/10.4028/www.scientific.net/kem.601.147.

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The paper presents a complex three-dimensional model of the human knee joint, containing bones, ligaments, menisci, tibial and femoral cartilages. To investigate the role of the articular cartilage in the developing of the osteoarthritis, to analyze and simulate the biomechanical behavior of the human knee joint, a finite element analysis was performed. The non-linearities are due to the presence of the contact elements modeled between components surfaces and to the nonlinear properties of the cartilage, applying a load of 800 N and 1500 N, for 0o in flexion. The results show that misalignment

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25

Joiner, G. A., E. R. Bogoch, K. P. Pritzker, M. D. Buschmann, A. Chevrier, and F. S. Foster. "High Frequency Acoustic Parameters of Human and Bovine Articular Cartilage following Experimentally-Induced Matrix Degradation." Ultrasonic Imaging 23, no. 2 (2001): 106–16. http://dx.doi.org/10.1177/016173460102300203.

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Matrix degradation and proteoglycan loss in articular cartilag eare features of early osteoarthritis. To determine the effect of matrix degradation and proteoglycan loss on ultrasound propagation in cartilage, we used papain and interleukin-1α to degrade the matrix proteoglycans of human and bovine cartilage samples, respectively. There is also minor collagen alteration associated with these chemical degradation methods. We compared the speed of sound and frequency dependent attenuation (20–40 MHz) of control and experimental paired samples. We found that a loss of matrix proteoglycans and col

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26

Weilin, Sang, and Ma Jinzhong. "Articular Cartilage Changes." Orthopedics 31, no. 10 (2008): 1–4. https://doi.org/10.3928/1477447-20110525-19.

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The morphologic changes of articular cartilage with bone grafting to fill subchondral bone defects were studied in 23-month-old New Zealand rabbits with bilateral tibial subchondral bone defects. The defects were made approximately 5 mm below the articular surface and were covered with surrounding tissues. The right side was filled with calcium sulfate bone graft, and the left side was filled with acrylic cement as control. The articular cartilage above the fillers was harvested 12 weeks postoperatively. Gross observation, histological examination, and transmission electron microscope observat

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27

Jurvelin, J., A.-M. Säämänen, J. Arokoski, H. J. Helminen, I. Kiviranta, and M. Tammi. "Biomechanical Properties of the Canine Knee Articular Cartilage as Related to Matrix Proteoglycans and Collagen." Engineering in Medicine 17, no. 4 (1988): 157–62. http://dx.doi.org/10.1243/emed_jour_1988_017_042_02.

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The instant, creep and equilibrium responses of canine knee articular cartilages were determined after a constant load application with an in situ indentation creep test and related to the chemical composition of the tissue. Instantly, the cartilage stiffness correlated inversely with the proportion of proteoglycans (PGs) extractable with guanidium chloride. The tibial cartilage, rich in PGs but relatively poor in collagen, showed a low resistance to instant rearrangement of the solid matrix after load application. However, the resistance of the tibial cartilage to water flow during creep defo

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28

Ulrich-Vinther, Michael, Michael D. Maloney, Edward M. Schwarz, Randy Rosier, and Regis J. OʼKeefe. "Articular Cartilage Biology." Journal of the American Academy of Orthopaedic Surgeons 11, no. 6 (2003): 421–30. http://dx.doi.org/10.5435/00124635-200311000-00006.

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29

Rosenberg, Lawrence C. "Articular Cartilage Lesions." Journal of Bone & Joint Surgery 87, no. 4 (2005): 921–22. http://dx.doi.org/10.2106/00004623-200504000-00033.

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30

Dalziel, Rod. "The articular cartilage." Sports Medicine, Training and Rehabilitation 2, no. 3-4 (1991): 269–72. http://dx.doi.org/10.1080/15438629109511926.

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31

Grande, Daniel A., John A. Schwartz, Eric Brandel, Nadeen O. Chahine, and Nicholas Sgaglione. "Articular Cartilage Repair." CARTILAGE 4, no. 4 (2013): 281–85. http://dx.doi.org/10.1177/1947603513494402.

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32

Trippel, Stephen B. "Articular cartilage research." Current Opinion in Rheumatology 2, no. 5 (1990): 777–82. http://dx.doi.org/10.1097/00002281-199002050-00015.

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33

Carson, Juan R. "Articular Cartilage Repair." Science Insights 2018, no. 2018 (2018): 1–4. http://dx.doi.org/10.15354/si.18.re082.

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34

Buckwalter, J. A. "Articular Cartilage Injuries." Clinical Orthopaedics and Related Research 402 (September 2002): 21–37. http://dx.doi.org/10.1097/00003086-200209000-00004.

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35

Hayes, Donald W., and Ryan K. Averett. "Articular Cartilage Transplantation." Clinics in Podiatric Medicine and Surgery 18, no. 1 (2001): 161–76. http://dx.doi.org/10.1016/s0891-8422(23)01172-2.

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36

Kheir, Ehab, and David Shaw. "Hyaline articular cartilage." Orthopaedics and Trauma 23, no. 6 (2009): 450–55. http://dx.doi.org/10.1016/j.mporth.2009.01.003.

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37

Chu, Constance R., F. Richard Convery, Wayne H. Akeson, Marvin Meyers, and David Amiel. "Articular Cartilage Transplantation." Clinical Orthopaedics and Related Research 360 (March 1999): 159–68. http://dx.doi.org/10.1097/00003086-199903000-00019.

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38

Newman, Alan P. "Articular Cartilage Repair." American Journal of Sports Medicine 26, no. 2 (1998): 309–24. http://dx.doi.org/10.1177/03635465980260022701.

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Articular cartilage can tolerate a tremendous amount of intensive and repetitive physical stress. However, it manifests a striking inability to heal even the most minor injury. Both the remarkable functional characteristics and the healing limitations reflect the intricacies of its structure and biology. Cartilage is composed of chondrocytes embedded within an extracellular matrix of collagens, proteoglycans, and noncollagenous proteins. Together, these substances maintain the proper amount of water within the matrix, which confers its unique mechanical properties. The structure and compositio

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39

Pawlak, Zenon. "Articular cartilage: Can Articular Cartilage be considered a Smart Material?" Clinical Case Reports and Clinical Study 2, no. 3 (2021): 1–2. http://dx.doi.org/10.61148/2766-8614/jccrcs/022.

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It has been shown that the “smart surface” of cartilage is highly hydrophilic when wet and hydrophobic when air-dry. The minimum surface energy of the bilayer was found to spread over a wide range of pH (6.5 to 9.5). The decreased number of bilayers changed the wettability and lowered the PL lubricant properties. In conclusion, a cartilage smart material can significantly react to changes pH and moisture.

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40

Li, Xue, Jin Duo Ye, Chun Qui Zhang, Qian Qian Tian, Xian Kang Wang, and Li Min Dong. "Numerical Simulation about Stretching Process in Different Layers of Cartilage." Applied Mechanics and Materials 441 (December 2013): 480–83. http://dx.doi.org/10.4028/www.scientific.net/amm.441.480.

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Cartilage with complex structure is a porous viscoelastic material. The direction of arrangement of collagen fibers in different layer regions directly affects the mechanical properties of the cartilage layer region. It is very important to use the method of numerical simulation for studying cartilage damage and repair through experimental measurements of cartilage mechanical parameters of the different layers. Because of the relatively small size of the cartilage, it is very difficult to measure mechanical parameters of cartilages by tensile test. The paper for main problems in the tensile te

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41

Chubinskaya, Susan, Charis Merrihew, Gabriella Cs-Szabo, et al. "Human Articular Chondrocytes Express Osteogenic Protein-1." Journal of Histochemistry & Cytochemistry 48, no. 2 (2000): 239–50. http://dx.doi.org/10.1177/002215540004800209.

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This study demonstrates for the first time that human articular chondrocytes express osteogenic protein-1 (OP-1). OP-1 was originally purified from bone matrix and was shown to induce cartilage and bone formation. Both OP-1 protein and message were present in human normal and osteoarthritic (OA) cartilages. OP-1 mRNA was upregulated in OA cartilage compared with normal adult tissues. However, the level of mature OP-1 protein in the same OA tissues was downregulated, whereas the pro-OP-1 remained high. Moreover, these two forms of OP-1 were localized in an inverted manner. Mature OP-1 was prima

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42

Davies, Sherri R., Shinji Sakano, Yong Zhu, and Linda J. Sandell. "Distribution of the Transcription Factors Sox9, AP-2, and [Delta]EF1 in Adult Murine Articular and Meniscal Cartilage and Growth Plate." Journal of Histochemistry & Cytochemistry 50, no. 8 (2002): 1059–65. http://dx.doi.org/10.1177/002215540205000808.

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The control of extracellular matrix (ECM) production is important for the development, maintenance, and repair of cartilage tissues. Matrix molecule synthesis is generally regulated by the rate of gene transcription determined by DNA transcription factors. We have shown that transcription factors Sox9, AP-2, and [delta]EF1 are able to alter the rate of CD-RAP transcription in vitro: Sox9 upregulates, AP-2 exhibits biphasic effects, and [delta]EF1 represses expression of the CD-RAP gene. To correlate these in vitro activities in vivo, transcription factors were co-immunolocalized with ECM prote

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43

Gustafson, Scott B., Gayle W. Trotter, Robert W. Norrdin, Robert H. Wrigley, and C. Lamar. "Evaluation of intra-articularly administered sodium monoiodoacetate-induced chemical injury to articular cartilage of horses." American Journal of Veterinary Research 53, no. 7 (1992): 1193–202. http://dx.doi.org/10.2460/ajvr.1992.53.7.1193.

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Summary Three doses of sodium monoiodoacetate (mia) were used to induce degenerative changes in articular cartilage in middle carpal joints of horses. Twelve young (2- to 5-year-old) horses, free of lameness, were randomly allotted to 3 groups. One middle carpal joint of each horse was injected with 0.9% NaCl solution (control joint). The contralateral middle carpal joint was injected with 0.09 mg of MlA/kg of body weight (group 1); 0.12 mg/kg (group 2); or 0.16 mg/kg (group 3). After mia administration, horses were allowed ad libitum exercise in a 2-acre paddock for 12 weeks. At the end of th

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44

Cha, Ryota, Shuji Nakagawa, Yuji Arai, et al. "Enhancing Cartilage Metabolism in Rats through a Novel Thermal Stimulation Technique with Photosensitizers." International Journal of Molecular Sciences 25, no. 12 (2024): 6728. http://dx.doi.org/10.3390/ijms25126728.

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Although the moderate thermal stimulation of articular cartilage exerts chondroprotective effects, it is difficult to effectively heat deep articular cartilage with conventional methods. Photosensitizers increase the ambient temperature using near-infrared (NIR) radiation, which has high tissue permeability. We hypothesized that the intra-articular administration of photosensitizers and NIR irradiation would exert a greater heating effect on articular cartilage. We aimed to evaluate the heating effect of this method on cultured chondrocytes and rat knee cartilage. In vitro, we irradiated a pho

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45

Wu, J. P., and T. B. Kirk. "Study of Altered Mechanical Properties of Articular Cartilage in Relation to the Collagen Network." Advanced Materials Research 41-42 (April 2008): 9–14. http://dx.doi.org/10.4028/www.scientific.net/amr.41-42.9.

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Articular cartilage is a semitransparent elastic material that covers on the two articulating bones in synovial joints. It acts as a cushion between the bones that transfers loads from one to another while attenuating dynamic stresses and providing almost frictionless contact surfaces for normal use of synovial joints without pains. Osteoarthritis causes a chronic joint pain and it is mainly due to malfunction of articular cartilage. The mechanical function of articular cartilage is derived from its unique microstructure. Therefore, study of the relationship between the mechanical function and

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46

Hayashi, Kei, Brian Caserto, Mary Norman, Hollis Potter, Matthew Koff, and Sarah Pownder. "Magnetic Resonance Imaging T2 Values of Stifle Articular Cartilage in Normal Beagles." Veterinary and Comparative Orthopaedics and Traumatology 31, no. 02 (2018): 108–13. http://dx.doi.org/10.3415/vcot-17-03-0093.

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Objectives The purpose of this study was to evaluate regional differences of canine stifle articular cartilage using the quantitative magnetic resonance imaging (MRI) technique of T2 mapping. Methods Fourteen stifle joints from seven juvenile male Beagle dogs with no evidence or prior history of pelvic limb lameness were imaged ex vivo using standard of care fast spin echo MRI and quantitative T2 mapping protocols. Regions of interest were compared between the femoral, patellar and tibial cartilages, as well as between the lateral and medial femorotibial compartments. Limbs were processed for

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A Soliman, Soha. "MMP-9 Expression in Normal Rabbit Chondrocytes." Cytology & Histology International Journal 5, no. 1 (2021): 1–9. http://dx.doi.org/10.23880/chij-16000131.

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Chondrocytes regulate anabolic and catabolic processes to maintain the extracellular matrix components. Catabolic activities depend on the proteolytic action of the matrix -degrading enzymes including ADAMTS (A disintegrin and metalloproteinases) and MMP (Matrix Metalloproteinase). The current study explored the distribution of MMP-9 in normal articular cartilages of the embryos rabbit. Articular cartilage has grown by appositional growth that the perichondrial stem cells differentiate into chondrocytes. MMP-9 positive perichondrial stem cells or chondroblasts and early chondrocytes. Mature ch

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48

Karpiński, Robert, Łukasz Jaworski, Józef Jonak, and Przemysław Krakowski. "Stress distribution in the knee joint in relation to tibiofemoral angle using the finite element method." MATEC Web of Conferences 252 (2019): 07007. http://dx.doi.org/10.1051/matecconf/201925207007.

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The article presents the results of a preliminary study on the structural analysis of the knee joint, considering changes in the mechanical properties of the articular cartilage of the joint. Studies have been made due to the need to determine the tension distribution occurring in the cartilage of the human knee. This distribution could be the starting point for designing custom made human knee prosthesis. Basic anatomy, biomechanical analysis of the knee joint and articular cartilage was introduced. Based on a series of computed tomography [CT] scans, the 3D model of human knee joint was reve

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Abbass, Sadiq Jafer, and Farah Mohammed Reda Abdulateef. "FINITE ELEMENT ANALYSIS OF HUMAN AND ARTIFICIAL ARTICULAR CARTILAGE." Journal of Engineering 18, no. 04 (2023): 443–58. http://dx.doi.org/10.31026/j.eng.2012.04.06.

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Joint diseases, such as osteoarthritis, induce pain and loss of mobility to millions of people around the world. Current clinical methods for the diagnosis of osteoarthritis include X-ray, magnetic resonance imaging, and arthroscopy. These methods may be insensitive to the earliest signs of osteoarthritis. This study investigates a new procedure that was developed and validated numerically for use in the evaluation of cartilage quality. This finite element model of the human articular cartilage could be helpful in providing insight into mechanisms of injury, effects of treatment, and the role

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Frame, K., H. M. Burbidge, K. Thompson, E. C. Firth, and W. J. Bruce. "A comparison of the effects of joint immobilisation, twice-daily passive motion, and voluntary motion on articular cartilage healing in sheep." Veterinary and Comparative Orthopaedics and Traumatology 15, no. 01 (2002): 23–29. http://dx.doi.org/10.1055/s-0038-1632709.

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SummaryIn this study, articulated transarticular external skeletal fixators were used to examine the effects of joint immobilisation, twice-daily passive range-of-motion exercises, and voluntary motion on articular cartilage healing and other joint parameters. Abaxial articular cartilage lesions demonstrated superior cartilage healing to axial lesions. Twice-daily passive range of motion exercises failed to improve the quality of articular cartilage repair when compared with joint immobilisation. Voluntary motion resulted in superior articular cartilage repair tissue with maintenance of near n

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