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1

International, Journal of Medical Science and Innovative Research (IJMSIR). "Atypical Meigs syndrome: A rare case with Review of literature." International Journal of Medical Science and Innovative Research (IJMSIR) 9, no. 1 (2024): 66–69. https://doi.org/10.5281/zenodo.15364083.

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<strong>Abstract</strong> Meigs Syndrome is a rare presentation which includes a benign ovarian tumor that is fibroma along with ascites and pleural effusion. One percent of ovarian tumors present as Meigs syndrome. Some patients present with either ascites or pleural effusion with benign tumor of ovary which is classified as &lsquo;Atypical or Incomplete Meigs syndrome&rsquo;. The syndrome is common in postmenopausal women around fifty years of age and its peak incidence is seen in the seventh decade. Various theories have been proposed for pathophysiology of as cites and pleural effusion in
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2

Thaker, DA, A. Dettrick, and PJ Stride. "A pseudo case of atypical pseudo-Meigs syndrome." Indian Journal of Cancer 48, no. 3 (2011): 364. http://dx.doi.org/10.4103/0019-509x.84914.

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3

Bowler, Taylor, Mary Thomson, and Sandhyarani Dasaraju. "Pseudo-Meigs syndrome: a rare cause of abdominal ascites in a patient with an ovarian mass." BMJ Case Reports 18, no. 4 (2025): e263547. https://doi.org/10.1136/bcr-2024-263547.

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Meigs syndrome is a rare phenomenon seen in approximately 1% of patients diagnosed with ovarian tumours. It is defined as a triad of a benign ovarian tumour, pleural effusion and ascites with complete resolution of symptoms following surgical intervention. This constellation of findings can be confused with several diagnoses, ranging from metastatic ovarian cancer to decompensated cirrhosis. Herein, we present a young woman presenting with new ascites, initially thought to be due to cirrhotic portal hypertension and found to have an atypical presentation of pseudo-Meigs syndrome, in the settin
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4

Choi, Seung-Yeon, Jin-Sun Park, Jeong-Won Lee, Byoung-Gie Kim, and Duk-Soo Bae. "A rare case of primary ovarian leiomyoma with atypical Meigs' syndrome." Korean Journal of Obstetrics & Gynecology 55, no. 4 (2012): 285. http://dx.doi.org/10.5468/kjog.2012.55.4.285.

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5

Dubey, Sunita, Poonam Goel, Nidhi Pandey, and Pavithra H. N. "Pseudo-Meigs syndrome: a rare presentation of pedunculated fibroid." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 9, no. 7 (2020): 3052. http://dx.doi.org/10.18203/2320-1770.ijrcog20202756.

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Serosal fibroid of uterus are usually asymptomatic but rarely; it may present with atypical symptoms to simulate malignancy and needs extensive evaluation. Authors are reporting a case of 26 years old P1L1 female with history of asymptomatic multiple intramural fibroids since 6 years came with complained of progressively increasing abdominal distension and mild pain abdomen from 2-3 months. On evaluation, she had ascites, pleural effusion and raised Ca-125. MR imaging of pelvis revealed moderate ascites and pedunculated serosal fibroid in addition to intramural fibroids with normal bilateral o
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6

Ricci, Giuseppe, Stefania Inglese, Alberto Candiotto, et al. "Ascites in puerperium: a rare case of atypical pseudo-Meigs’ syndrome complicating the puerperium." Archives of Gynecology and Obstetrics 280, no. 6 (2009): 1033–37. http://dx.doi.org/10.1007/s00404-009-1041-0.

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7

Tsakiri, Sophia P., Chirine A. Turk, Kevin P. Lally, Karuna Garg, and Brenda Morris. "Atypical Meigs’ syndrome in a neonate with ovarian torsion associated with an ovarian dermoid cyst." Pediatric Surgery International 21, no. 5 (2005): 407–9. http://dx.doi.org/10.1007/s00383-005-1368-y.

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8

Yip, H. K., L. W. Huang, Y. H. Lin, and J. L. Hwang. "Massive ascites caused by a large pedunculated subserosal uterine leiomyoma that has feeding arteries from peripheral tissues and exhibits elevated CA125: A case report of atypical Pseudo-Meigs’ syndrome." Journal of Obstetrics and Gynaecology 34, no. 1 (2013): 107. http://dx.doi.org/10.3109/01443615.2013.832736.

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9

Senthil, Raja, ArunVisakh Ramachandran Nair, Thara Pratap, and Chitrathara Kesavan. "Isolated fluorodeoxyglucose avid right pleural deposits/effusion on an F-18 fluorodeoxyglucose positron emission tomography/computed tomography in patients with ovarian cancer – Are they almost certainly metastatic? An extrapolation of atypical meigs' syndrome." Indian Journal of Nuclear Medicine 34, no. 1 (2019): 42. http://dx.doi.org/10.4103/ijnm.ijnm_102_18.

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10

AO, Sule-Odu, Andu Babatunde, and Akiseku Adeniyi. "Subserous uterine fibroid presenting atypically with features of pseudo-meig's syndrome." Tropical Journal of Obstetrics and Gynaecology 35, no. 1 (2018): 93. http://dx.doi.org/10.4103/tjog.tjog_75_17.

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11

Thomas, Sunitha, Laxmi Radhakrishnan, Latha Abraham, and Anna Matthai. "Uterine Angioleiomyoma with Atypia, Raised CA-125 Levels, and Pseudo-Meigs Syndrome: An Alarming Presentation." Case Reports in Pathology 2012 (2012): 1–4. http://dx.doi.org/10.1155/2012/519473.

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Angioleiomyomas are benign mesenchymal tumours commonly occurring in the subcutis of extremities. They are typically composed of interlacing fascicles of smooth muscle cells with intersecting vascular channels. Angioleiomyomas of the uterus are rare with only very few case reports available in literature. Herein, we report a case of this rare entity in a 47-year-old woman owing to its highly unusual features of cellular atypia, raised CA-125 levels, and pseudo Meigs syndrome.
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12

Hirata, Tomohiro, Hiroto Yamada, Sachiko Kimura, Hiroyuki Yanai, and Tomoo Daifu. "Gynandroblastoma with massive ascites as atypical Meigs syndrome." Pediatrics International 67, no. 1 (2025). https://doi.org/10.1111/ped.70067.

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13

Murayama, Yoko, Yoshiro Kamoi, Hiroyuki Yamamoto, Jun Isogai, and Takahiro Tanaka. "Meigs’ syndrome mimicking heart failure with preserved ejection fraction: a case report." BMC Cardiovascular Disorders 20, no. 1 (2020). http://dx.doi.org/10.1186/s12872-020-01718-4.

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Abstract Background Meigs’ syndrome is a rare disease characterized by a triad of presentations, including benign ovarian tumor, ascites, and pleural effusion. However, a clinical diagnosis of Meigs’ syndrome remains challenging because pleural and ascitic effusions can be common findings in a variety of underlying conditions. Furthermore, these findings can often be misdiagnosed as pleural and peritoneal dissemination caused by potentially malignant tumors, leading to the administration of improper treatment. Case presentation We described a case of an 85-year-old postmenopausal female patien
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14

Potiris, Anastasios, Ioannis S. Pateras, Nektarios Koufopoulos, et al. "Rare giant ovarian thecoma presented as atypical/incomplete Meigs' syndrome: A case image report." Clinical Case Reports 12, no. 11 (2024). http://dx.doi.org/10.1002/ccr3.9558.

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Key Clinical MessageWe present a 39‐centimeter thecoma with ascites and elevated Ca‐125 values which is compatible with an atypical/incomplete Meigs' syndrome. Giant ovarian masses with elevated Ca‐125 values and ascites are an alarming combination, although Gynecologists should be aware that there are also benign entities that mimic advanced stage ovarian cancer.
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15

Wang, Hongyu, Jinbao Wang, Jianping Yu, and Xiaopeng Han. "Giant adult granulosa cell tumor and “atypical” Meigs syndrome: A case report." Asian Journal of Surgery, March 2024. http://dx.doi.org/10.1016/j.asjsur.2024.03.064.

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16

Gianchandani Gyani, Sanjeev G., Meenakshi Yeola, Resha O. Keshwani, Sachin G. Gianchandani, and Pankaj Katariya. "Atypical Psuedo-Demons-Meigs Syndrome Presenting As Acute Dyspnoea With Pseudomembranous Colitis." Cureus, January 21, 2024. http://dx.doi.org/10.7759/cureus.52689.

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17

Omori, Ginji, Yohei Arihara, Tomoyuki Abe, et al. "A Case of Atypical Pseudo-Meigs' Syndrome without Pleural Effusion due to Ovarian Metastasis from Sigmoid Colon Cancer." Internal Medicine, 2023. http://dx.doi.org/10.2169/internalmedicine.0157-22.

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18

Mir, Marwa, Bella A. Gnakou, Hamid Shaaban, Gunwant Guron, and Zafar Jamil. "A Case of Atypical Meig’s Syndrome Presenting With Pleural and Pericardial Effusion." Cureus, January 25, 2025. https://doi.org/10.7759/cureus.77976.

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