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1

Ahmed, Mohamed H. "Biochemical Markers." American Journal of Clinical Pathology 127, no. 1 (January 2007): 20–22. http://dx.doi.org/10.1309/jxwum661t8vt1etx.

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2

Rothstein, Jeffrey. "Biochemical markers: Pro." Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders 3, sup1 (September 2002): S81. http://dx.doi.org/10.1080/146608202320374381.

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3

Mitsumoto, Hiroshi. "Biochemical markers: Con." Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders 3, sup1 (September 2002): S83. http://dx.doi.org/10.1080/146608202320374390.

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4

Strong, Michael J. "Biochemical markers: Summary." Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders 3, sup1 (September 2002): S85—S90. http://dx.doi.org/10.1080/146608202320374408.

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5

Sandberg, Dr K. "3. Biochemical markers." Animal Genetics 20, no. 1 (April 24, 2009): 56–83. http://dx.doi.org/10.1111/j.1365-2052.1989.tb01910.x.

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6

Seishima, Mitsuru, Makiko Suzuki, and Satoshi Maeda. "Atherosclerosis and biochemical markers." SEIBUTSU BUTSURI KAGAKU 48, no. 4 (2004): 143–46. http://dx.doi.org/10.2198/sbk.48.143.

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7

Selroos, Olof B. N. "Biochemical Markers in Sarcoidosis." CRC Critical Reviews in Clinical Laboratory Sciences 24, no. 3 (January 1986): 185–216. http://dx.doi.org/10.3109/10408368609110273.

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8

Đerić, Mirjana, Sunčica Kojić-Damjanov, Velibor Čabarkapa, and Nevena Eremić. "Biochemical Markers of Atherosclerosis." Journal of Medical Biochemistry 27, no. 2 (January 1, 2008): 148–53. http://dx.doi.org/10.2478/v10011-008-0008-1.

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Biochemical Markers of AtherosclerosisThis paper is a brief review of some lipid parameters and serum markers of inflammation in a view of their predictive relevance for the atherosclerotic disease. A discourse on the importance of measuring different lipids and lipoproteins, concentration of LDL particles and apolipoprotein levels is still underway. Also, the recommendations for apolipoprotein (a), phenotypization and other lipid markers have not yet been established. In recent years the recommendations imply simultaneous measuring of multiple markers and calculating the lipid index values such as lipid tetrad index (LTI), lipid pentad index (LPI) and atherogenic index of plasma (AIP). Several circulating markers of inflammation such as C-reactive protein, serum fibrinogen and elevated leukocyte number, are consistently associated with atherosclerosis. In spite of a lack of evidence on measuring the C-reactive protein in a wide population, the guidelines for its application in diagnostics and therapy of coronary heart disease were developed. Some proinflammatory cytokines, adhesion molecules and markers of leukocyte activation are promising markers, requiring, however, more detailed prospective evaluation. The question to be elucidated is if these inflammatory markers are directly involved in the pathogenic process.
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9

Kanis, John. "Biochemical markers in osteoporosis." Scandinavian Journal of Clinical and Laboratory Investigation 57 (1997): 6–11. http://dx.doi.org/10.3109/00365519709168303.

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10

Ratcliffe, Anthony, and Markus J. Seibel. "Biochemical markers of osteoarthritis." Current Opinion in Rheumatology 2, no. 5 (October 1990): 770–76. http://dx.doi.org/10.1097/00002281-199002050-00014.

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11

Kanis, John A. "Biochemical markers in osteoporosis." Scandinavian Journal of Clinical and Laboratory Investigation 57, sup227 (January 1997): 6–11. http://dx.doi.org/10.1080/00365519709168303.

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12

Jung, Rex E., Ronald A. Yeo, Stephen J. Chiulli, Wilmer L. Sibbitt, David C. Weers, Blaine L. Hart, and William M. Brooks. "Biochemical markers of cognition." NeuroReport 10, no. 16 (November 1999): 3327–31. http://dx.doi.org/10.1097/00001756-199911080-00014.

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13

Ikizler, T. Alp. "Biochemical markers: Clinical aspects." Journal of Renal Nutrition 7, no. 2 (April 1997): 61–64. http://dx.doi.org/10.1016/s1051-2276(97)90039-x.

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14

Paselk, R. "Biochemical Markers for Cancer." Biochemical Education 13, no. 1 (January 1985): 43. http://dx.doi.org/10.1016/0307-4412(85)90154-2.

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15

Stadtman, E. R. "Biochemical markers of aging." Experimental Gerontology 23, no. 4-5 (January 1988): 327–47. http://dx.doi.org/10.1016/0531-5565(88)90036-8.

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16

Samoilova, I. G., M. V. Matveeva, and D. E. Galyukova. "Biochemical markers of autism." Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova 124, no. 1 (2024): 55. http://dx.doi.org/10.17116/jnevro202412401155.

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17

Duffy, M. J. "Biochemical markers as prognostic indices in breast cancer." Clinical Chemistry 36, no. 2 (February 1, 1990): 188–91. http://dx.doi.org/10.1093/clinchem/36.2.188.

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Abstract Traditional prognostic markers in breast cancer include histological variables such as tumor size, grade, and axillary node status. In recent years some new potential prognostic markers of a biochemical nature have been described: estradiol receptors, progesterone receptors, epidermal growth factor receptors, erbB-2 proto-oncogene, and certain proteolytic enzymes. None of these new markers excels axillary node status as a prognostic marker. Biochemical markers can, however, be evaluated with use of minimal surgery and may help distinguish the minority of aggressive axillary-node-negative breast cancers.
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18

Watts, Nelson B. "Clinical Utility of Biochemical Markers of Bone Remodeling." Clinical Chemistry 45, no. 8 (August 1, 1999): 1359–68. http://dx.doi.org/10.1093/clinchem/45.8.1359.

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Abstract Remodeling is essential for bone health. It begins with resorption of old bone by osteoclasts, followed by the formation of new bone by osteoblasts. Remodeling is coupled (formation is linked to resorption). After middle age or perhaps beginning earlier, bone loss occurs because resorption exceeds formation. This imbalance is accentuated by estrogen deficiency as well as by many diseases and conditions. Biochemical markers that reflect remodeling and can be measured in blood or urine include resorption markers (e.g., collagen cross-links) and formation markers (e.g., alkaline phosphatase). Bone markers exhibit substantial short-term and long-term fluctuations related to time of day, phase of the menstrual cycle, and season of the year, as well as diet, exercise, and anything else that alters bone remodeling. These biological factors, in addition to assay imprecision, produce significant intra- and interindividual variability in markers. Bone marker measurements are noninvasive, inexpensive, and can be repeated often. Unfortunately, most of the studies that provided insight on clinical situations did not focus on markers as a primary endpoint. Bone markers have been useful in clinical practice and have been helpful in understanding the pathogenesis of osteoporosis and the mechanism of action of therapies. In clinical trials, markers aid in selecting optimal dose and in understanding the time course of onset and resolution of treatment effect. Clinical questions that might be answered by bone markers include diagnosing osteoporosis, identifying “fast bone losers” and patients at high risk of fracture, selecting the best treatment for osteoporosis, and providing an early indication of the response to treatment. Additional information is needed to define specific situations and cut points to allow marker results to be used with confidence in making decisions about individual patients.
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19

Cheung, K. L., S. E. Pinder, C. Paish, A. H. Sadozye, S. Y. Chan, A. J. Evans, R. W. Blamey, and J. F. R. Robertson. "The Role of Blood Tumor Marker Measurement (Using a Biochemical Index Score and C-Erbb2) in Directing Chemotherapy in Metastatic Breast Cancer." International Journal of Biological Markers 15, no. 3 (July 2000): 203–9. http://dx.doi.org/10.1177/172460080001500310.

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The role of blood tumor markers in monitoring response in advanced breast cancer is established in endocrine therapy and standard chemotherapy. This study examines marker levels in patients receiving new chemotherapy regimens. Thirty patients were recruited into two multicenter trials in which docetaxel-based regimens were used in 15 patients. The other 15 received doxorubicin-based regimens. Biochemical response calculated from a score using CA15.3, CEA and ESR was compared with UICC response. Marker changes at 2, 4 and 5 months correlated with UICC response at 3, 41/2 and 6 months, respectively (p < 0.03). Eleven patients achieved both clinical/radiological and biochemical response at the end of treatment; markers had not yet returned to below cutoffs in seven, suggesting a possible advantage to continue chemotherapy. No patient showed a biochemical response whilst judged clinically/radiologically progressive. Nineteen patients had progressed either clinically/radiologically or biochemically at six months; of these, eight showed progression assessed earlier by markers so that a median of four cycles of chemotherapy could have been saved. Measurements of serum c-erbB2 showed a correlation with tissue c-erbB2 staining in the primary tumor (p < 0.003). Among the patients with positive tissue staining, sequential changes in serum c-erbB2 completely paralleled initial response.
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20

Adeli, Khosrow, Victoria Higgins, Michelle Nieuwesteeg, Joshua E. Raizman, Yunqi Chen, Suzy L. Wong, and David Blais. "Biochemical Marker Reference Values across Pediatric, Adult, and Geriatric Ages: Establishment of Robust Pediatric and Adult Reference Intervals on the Basis of the Canadian Health Measures Survey." Clinical Chemistry 61, no. 8 (August 1, 2015): 1049–62. http://dx.doi.org/10.1373/clinchem.2015.240515.

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Abstract BACKGROUND Biological covariates such as age and sex can markedly influence biochemical marker reference values, but no comprehensive study has examined such changes across pediatric, adult, and geriatric ages. The Canadian Health Measures Survey (CHMS) collected comprehensive nationwide health information and blood samples from children and adults in the household population and, in collaboration with the Canadian Laboratory Initiative on Pediatric Reference Intervals (CALIPER), examined biological changes in biochemical markers from pediatric to geriatric age, establishing a comprehensive reference interval database for routine disease biomarkers. METHODS The CHMS collected health information, physical measurements, and biosamples (blood and urine) from approximately 12 000 Canadians aged 3–79 years and measured 24 biochemical markers with the Ortho Vitros 5600 FS analyzer or a manual microplate. By use of CLSI C28-A3 guidelines, we determined age- and sex-specific reference intervals, including corresponding 90% CIs, on the basis of specific exclusion criteria. RESULTS Biochemical marker reference values exhibited dynamic changes from pediatric to geriatric age. Most biochemical markers required some combination of age and/or sex partitioning. Two or more age partitions were required for all analytes except bicarbonate, which remained constant throughout life. Additional sex partitioning was required for most biomarkers, except bicarbonate, total cholesterol, total protein, urine iodine, and potassium. CONCLUSIONS Understanding the fluctuations in biochemical markers over a wide age range provides important insight into biological processes and facilitates clinical application of biochemical markers to monitor manifestation of various disease states. The CHMS-CALIPER collaboration addresses this important evidence gap and allows the establishment of robust pediatric and adult reference intervals.
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21

Khatoon, Arifa, Sumeet Verma, Gayatri Wadiye, and Anuprita Zore. "Molecular markers and their potentials." International Journal of Bioassays 5, no. 01 (January 1, 2016): 4706. http://dx.doi.org/10.21746/ijbio.2016.01.003.

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The use of molecular markers, revealing polymorphism at the DNA level, has been playing an increasing part in plant molecular biotechnology and their genetic studies. There are three different types of markers viz. morphological, biochemical and DNA based molecular markers. These DNA based markers are differentiating in two types 1. Non PCR based (RFLP) and 2. PCR based markers (RAPD, AFLP, SSR, SNP etc.). Amongst others, the microsatellite DNA marker is one of the most widely used marker due to its easy use by simple PCR, followed by a denaturing gel electrophoresis. SNP (Single Nucleotide Polymorphism) is nowadays is the one which is used mainly. In this review, we are going to discuss about the biochemical and molecular markers which are recently developed, the important characteristics of molecular markers their advantages, disadvantages and the applications of these markers in comparison with other markers types.
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22

Franco, Leonardo, and Mario Alejandro Ortíz Salazar. "Biochemical markers of bone metabolism." Revista Estomatología 18, no. 1 (September 28, 2017): 30–34. http://dx.doi.org/10.25100/re.v18i1.5707.

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The quantity and quality of bone tissue renewal are dependent on the generation of new bone (deposition) mediated by osteoblasts and the loss (resorption) mediated by osteoclasts. For each of these processes there are important markers that can be measured in serum or urine.
 Resorption markers are products of metabolic degradation of bone matrix in particu-lar of the type I collagen (hydroxyproline, pyridinoline and deoxypyridinoline). In addition, the resorptive activity can also be evaluated through the tartrate resistant acid phosphatase (TRAP) and calcium-creatinine ratio in urine. Bone formation markers are collagen proteins (ALP, OCN), non collagen (ONC, OPN, BSP) or fragments of collagen synthesis (procollagen peptides).
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23

Rosen, Clifford J., and Alan Tenenhouse. "Biochemical markers of bone turnover." Postgraduate Medicine 104, no. 4 (October 1998): 101–14. http://dx.doi.org/10.3810/pgm.1998.10.447.

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24

Accomando, Salvatore. "Biochemical markers in Celiac disease." Frontiers in Bioscience S2, no. 1 (2010): 313–17. http://dx.doi.org/10.2741/s66.

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25

Bapayeva, G. B. "Biochemical markers of premature birth." Journal of obstetrics and women's diseases 54, no. 3 (November 1, 2005): 38–41. http://dx.doi.org/10.17816/jowd83449.

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Summary: In this article the results of the research of diagnostic importance of myoglobin determination in peripheral blood and amniotic fluid, fetal fibronectin examination in cervicovaginal composition contents of a pregnant woman are represented in prediction of premature birth.
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26

Koshul’ko, P. A., M. S. Kovalenko, Yu V. Abalenihina, A. I. Mirov, O. E. Golofast, and E. D. Rokunov. "Biochemical markers of missed pregnancy." Problemy reproduktsii 27, no. 6 (2021): 138. http://dx.doi.org/10.17116/repro202127061138.

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27

Lyubimova, N. V., and N. E. Kushlinskiy. "Biochemical markers of bone metastasis." Advances in molecular oncology 2, no. 1 (June 2, 2015): 061. http://dx.doi.org/10.17650/2313-805x.2015.2.1.061-075.

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28

Lyubimova, N. V., and N. E. Kushlinskiy. "Biochemical markers of bone metastasis." Advances in molecular oncology 2, no. 1 (June 2, 2015): 061. http://dx.doi.org/10.17650/2313-805x.2015.2.1.61-75.

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29

Kovářů, H., F. Kovářů, A. Fišerová, P. Zelníčková, and E. Matalová. "Biochemical Markers of Lymphocyte Maturation." Acta Veterinaria Brno 71, no. 4 (2002): 503–8. http://dx.doi.org/10.2754/avb200271040503.

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30

Delmas, Pierre D. "Biochemical markers of bone turnover." Acta Orthopaedica Scandinavica 66, sup266 (January 1995): 176–82. http://dx.doi.org/10.3109/17453679509157687.

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31

Griesmacher, A., P. Peichl, P. Pointinger, R. Mateau, and H. Broll. "Biochemical markers in menopausal women." Scandinavian Journal of Clinical and Laboratory Investigation 57 (1997): 64–72. http://dx.doi.org/10.3109/00365519709168309.

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32

Apple, Fred. "Biochemical markers of thrombolytic success." Scandinavian Journal of Clinical and Laboratory Investigation 59 (1999): 60–66. http://dx.doi.org/10.3109/00365519909168328.

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33

Kemp, M., J. Donovan, H. Higham, and J. Hooper. "Biochemical markers of myocardial injury." British Journal of Anaesthesia 93, no. 1 (July 2004): 63–73. http://dx.doi.org/10.1093/bja/aeh148.

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34

Kerrigan, Richard W., and Ian K. Ross. "Extracellular Laccases: Biochemical Markers forAgaricusSystematics." Mycologia 80, no. 5 (September 1988): 689–95. http://dx.doi.org/10.1080/00275514.1988.12025602.

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35

Lyubimova, N. V., T. K. Churikova, M. G. Toms, and N. E. Kushlinskiy. "BIOCHEMICAL MARKERS OF NEUROENDOCRINAL TUMORS." Tambov University Reports. Series: Natural and Technical Sciences 21, no. 2 (2016): 494–510. http://dx.doi.org/10.20310/1810-0198-2016-21-2-494-510.

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36

Krstic, Danijela, Nenad Tomic, Branimir Radosavljevic, Natasa Avramovic, Vesna Dragutinovic, Sanja Radojevic Skodric, and Mirjana Colovic. "Biochemical Markers of Renal Function." Current Medicinal Chemistry 23, no. 19 (July 19, 2016): 2018–40. http://dx.doi.org/10.2174/0929867323666160115130241.

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37

Demers, Laurence M., Luis Costa, and Allan Lipton. "Biochemical Markers and Skeletal Metastases." Clinical Orthopaedics and Related Research 415 (October 2003): S138—S147. http://dx.doi.org/10.1097/01.blo0000092979.12414.54.

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38

Thompson, R. P. H. "Biochemical markers of liver disease." Current Opinion in Gastroenterology 1, no. 3 (May 1985): 377–89. http://dx.doi.org/10.1097/00001574-198505000-00002.

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39

Matull, W. R. "Biochemical markers of acute pancreatitis." Journal of Clinical Pathology 59, no. 4 (April 1, 2006): 340–44. http://dx.doi.org/10.1136/jcp.2002.002923.

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40

Engler, H., B. Thürlimann, and F. Riesen. "Biochemical Markers of Bone Remodelling." Oncology Research and Treatment 19, no. 2 (1996): 126–31. http://dx.doi.org/10.1159/000218778.

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41

Griesmacher, A., P. Peichl, P. Pointinger, R. Mateau, and H. Bröll. "Biochemical markers in menopausal women." Scandinavian Journal of Clinical and Laboratory Investigation 57, sup227 (January 1997): 64–72. http://dx.doi.org/10.1080/00365519709168309.

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42

Apple, Fred S. "Biochemical markers of thrombolytic success." Scandinavian Journal of Clinical and Laboratory Investigation 59, sup230 (January 1999): 60–66. http://dx.doi.org/10.1080/00365519909168328.

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43

Gao, F., and D. N. F. Harris. "Biochemical markers of cerebral damage." European Journal of Anaesthesiology 14, no. 2 (March 1997): 113–17. http://dx.doi.org/10.1097/00003643-199703000-00001.

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44

De Jongh, R., C. De Deyne, G. Kenis, G. Vundelinckx, L. Merckx, and R. Heylen. "Biochemical markers of brain ischaemia." European Journal of Anaesthesiology 15, Supplement 17 (January 1998): 14–15. http://dx.doi.org/10.1097/00003643-199801001-00011.

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45

Crofton, P. M., H. F. Stirling, E. Schönau, S. F. Ahmed, W. H. B. Wallace, J. C. Wade, R. Magowan, et al. "Biochemical Markers of Bone Turnover." Hormone Research 45, no. 1 (1996): 55–58. http://dx.doi.org/10.1159/000184832.

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46

Rambotti, Pietro. "Biochemical markers in lymphoproliferative diseases." Critical Reviews in Oncology/Hematology 2, no. 4 (January 1985): 297–321. http://dx.doi.org/10.1016/s1040-8428(85)80006-8.

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47

Shepherd, J. "Biochemical risk markers of CHD." Atherosclerosis 144 (May 1999): 144. http://dx.doi.org/10.1016/s0021-9150(99)80558-9.

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48

Seibel, Markus J. "Biochemical markers of bone remodeling." Endocrinology and Metabolism Clinics of North America 32, no. 1 (March 2003): 83–113. http://dx.doi.org/10.1016/s0889-8529(02)00077-4.

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49

Garnero, Patrick, and Pierre D. Delmas. "BIOCHEMICAL MARKERS OF BONE TURNOVER." Endocrinology and Metabolism Clinics of North America 27, no. 2 (June 1998): 303–23. http://dx.doi.org/10.1016/s0889-8529(05)70007-4.

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50

Gavaghan, Mary. "Biochemical Markers in Myocardial Injury." AORN Journal 70, no. 5 (November 1999): 839–54. http://dx.doi.org/10.1016/s0001-2092(06)61303-3.

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