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1

Su, Linlin, and 苏琳琳. "Drug transporters and blood-testis barrier dynamics." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2011. http://hub.hku.hk/bib/B47752816.

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Bexis, Sotiria. "The relationship between vascular structure, contractile proteins, vascular reactivity and blood pressure in animal models of hypertension /." Title page, contents and abstract only, 1997. http://web4.library.adelaide.edu.au/theses/09PH/09phb572.pdf.

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3

Mwaikambo, Bupe Rose. "Emerging roles for the CD36 scavenger receptor in neovascular ocular disease." Thesis, McGill University, 2008. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=115899.

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Ocular neovascularization (NV) associated with corneal NV, ischemic retinopathies and age-related macular degeneration is a leading cause of severe vision loss. While numerous contributing factors have been identified, the potential role of the CD36 scavenger receptor has been largely overlooked notwithstanding its crucial involvement in normal retinal function. Accordingly, the central aim of this work was to elucidate the contribution and regulation of CD36 during ocular NV using the cornea as a model.<br>Initial work investigating the role of CD36 10 maintaining corneal avascularity, an imp
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4

Jiang, Liying. "Exposure of endothelial cells to shear stress stimulates protein tryosine phosphorylation." Thesis, Georgia Institute of Technology, 1996. http://hdl.handle.net/1853/25421.

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5

Liang, Yan, and 梁艳. "Endothelial LKB1/AMPK signaling pathway in regulating energy and vascular homeostasis." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hdl.handle.net/10722/193460.

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Liver kinase B1 (LKB1), a serine/threonine kinase, is responsible for the activation of AMP-activated protein kinase (AMPK), the master regulator of energy metabolism. LKB1/AMPK signaling pathway possesses a wide range of biological functions in regulating cell cycle progression, cell polarity, senescence and inflammation. In cultured endothelial cells, the pro-senescence function of LKB1/AMPK signaling pathway has been observed. However, the mechanisms by which LKB1 is regulated in endothelial cells remain largely uncharacterized. Furthermore, little is known about the effects of activated en
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6

Waghulde, Harshal B. "Mapping and CRISPR/Cas9 Gene Editing for Identifying Novel Genomic Factors Influencing Blood Pressure." University of Toledo Health Science Campus / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=mco1470402637.

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7

Henninger, Nils. "Inhibiting Axon Degeneration in a Mouse Model of Acute Brain Injury Through Deletion of Sarm1." eScholarship@UMMS, 2017. http://escholarship.umassmed.edu/gsbs_diss/900.

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Traumatic brain injury (TBI) is a leading cause of disability worldwide. Annually, 150 to 200/1,000,000 people become disabled as a result of brain trauma. Axonal degeneration is a critical, early event following TBI of all severities but whether axon degeneration is a driver of TBI remains unclear. Molecular pathways underlying the pathology of TBI have not been defined and there is no efficacious treatment for TBI. Despite this significant societal impact, surprisingly little is known about the molecular mechanisms that actively drive axon degeneration in any context and particularly followi
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8

Chakaroun, Rima. "Effects of weight loss and exercise on chemerin serum concentrations and adipose tissue expression in human obesity." Doctoral thesis, Universitätsbibliothek Leipzig, 2015. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-158639.

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Chemerin is a chemoattractant adipokine that regulates adipogenesis and may induce insulin resistance. Chemerin serum concentrations are elevated in obese, insulin-resistant, and inflammatory states in vivo. Here we investigate the role of omental (OM) and subcutaneous (SC) adipose tissue chemerin and CMKLR1 messenger RNA (mRNA) expression in human obesity. In addition, we test the hypothesis that changes in chemerin serum concentrations are primarily associated with reduced body fat mass in the context of 3 weight loss intervention studies. Chemerin serum concentration was measured in 740 ind
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9

Julien, Mathéau A. "Mechanical Strain-Mediated Syndecan Regulation and Its Effects on Adhesion of Vascular Smooth Muscle Cells." Diss., Georgia Institute of Technology, 2005. http://hdl.handle.net/1853/7007.

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An injured vascular system has a substantial impact on an individuals overall health, and an understanding of the mechanisms that underlie blood vessel pathophysiology is required for the development of rational and effective treatment strategies. The phenotypic modulation of smooth muscle cells (SMC) during vascular injury, characterized by altered adhesion, migration and synthetic behavior, plays an important role in the eventual outcome. Specifically, the ability of SMCs to adhere to and remodel their extracellular environment via regulation of the syndecan class of cell adhesion molecule
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10

Babin, Patrick. "Lipoproteines et apolipoproteines plasmatiques chez les poissons teleosteens." Paris 6, 1987. http://www.theses.fr/1987PA066032.

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Caracterisation des lipoproteines plasmatiques et de leurs apolipoproteines chez salmo gairdneri. Determination de leur masse moleculaire et de leur densite. L'etude au long du cycle annuel de reproduction a permis de demontrer la presence de proteines vitellines ovulaires dans le plasma. De plus, le role des lipoproteines, plasmatiques dans la steroidogenese ovarienne a ete etudie
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11

Hattingh, Johann. "A comparative study of the plasma proteins of some Transvaal freshwater fish." Thesis, 2015. http://hdl.handle.net/10539/16740.

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12

Bexis, Sotiria. "The relationship between vascular structure, contractile proteins, vascular reactivity and blood pressure in animal models of hypertension / by Sotiria Bexis." Thesis, 1997. http://hdl.handle.net/2440/18970.

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Bibliography: leaves 216-239.<br>xiv, 246 leaves : ill. ; 30 cm.<br>The aim of this thesis is to examine the relationship between vascular reactivity, contractile proteins and blood pressure development in the spontaneously hypertensive rat (SHR). In addition, the influence of angiotensin II on blood pressure and vascular structure and function is investigated.<br>Thesis (Ph.D.)--University of Adelaide, Dept. of Clinical and Experimental Pharmacology, 1997
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13

Lord, Andrew P. D. (Andrew Peter Duncan). "IGF transfer from blood to tissue: comparison of IGF-I with analogs that bind poorly to binding proteins, using a vascular perfusion model : a thesis submitted to the University of Adelaide, South Australia, for the degree of Doctor of Philosophy." 1993. http://web4.library.adelaide.edu.au/theses/09PH/09phl866.pdf.

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Includes bibliographical references (leaves 188-217) Insulin-like growth factor-I circulates at high concentrations in blood, mainly complexed with IGF-binding proteins. The main objective of the thesis is to determine the general role played by plasma IGF-binding proteins in the regulation of IGF transfer from blood to tissues.
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14

Lord, Andrew P. D. (Andrew Peter Duncan). "IGF transfer from blood to tissue: comparison of IGF-I with analogs that bind poorly to binding proteins, using a vascular perfusion model / by Andrew Peter Duncan Lord." Thesis, 1993. http://hdl.handle.net/2440/21662.

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xxiii, 222 leaves : ill. ; 30 cm.<br>Insulin-like growth factor-I circulates at high concentrations in blood, mainly complexed with IGF-binding proteins. The main objective of the thesis is to determine the general role played by plasma IGF-binding proteins in the regulation of IGF transfer from blood to tissues.<br>Thesis (Ph.D.)--University of Adelaide, Dept. of Animal Science, 1994
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15

Sayers, Stephen P. "The effect of immobilization on muscle function, peripheral activation, evoked contractile properties of the muscle, and muscle proteins in the blood after eccentric exercise." 2001. https://scholarworks.umass.edu/dissertations/AAI3027254.

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The primary aim of this dissertation was to examine the role of short-term immobilization on muscle function recovery, excitability of the muscle, evoked contractile properties of the muscle, and muscle proteins in the blood after contraction-induced muscle injury. In Studies I and II, the effects of four days of immobilization on recovery of muscle function and serum creatine kinase (CK) activity after eccentric exercise was examined in 26 males, who were placed into one of three groups: immobilization, control, or light exercise. When the damaged elbow flexor muscles were immobilized or exer
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16

McNeilly, A. D., Ritchie Williamson, D. J. Balfour, C. A. Stewart, and C. Sutherland. "A high-fat-diet-induced cognitive deficit in rats that is not prevented by improving insulin sensitivity with metformin." 2012. http://hdl.handle.net/10454/6095.

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AIMS/HYPOTHESIS: We previously demonstrated that animals fed a high-fat (HF) diet for 10 weeks developed insulin resistance and behavioural inflexibility. We hypothesised that intervention with metformin would diminish the HF-feeding-evoked cognitive deficit by improving insulin sensitivity. METHODS: Rats were trained in an operant-based matching and non-matching to position task (MTP/NMTP). Animals received an HF (45% of kJ as lard; n = 24), standard chow (SC; n = 16), HF + metformin (144 mg/kg in diet; n = 20) or SC + metformin (144 mg/kg in diet; n = 16) diet for 10 weeks before retesting.
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17

Baverstock, P. R. (Peter Raymond) 1948. "Studies in the adaptation and evolution of the Australasian fauna : a collection / by P.R. Baverstock." 1987. http://hdl.handle.net/2440/38478.

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Collection of previously published articles<br>Includes Allozyme electrophoresis / B.J. Richardson, P.R. Baverstock and M. Adams (1986)<br>Includes bibliographies<br>2 v. :<br>Title page, contents and abstract only. The complete thesis in print form is available from the University Library.<br>Thesis (D. Sc.)--University of Adelaide, 1988
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18

(8801123), Robert E. Bergia. "Relations and effects of dietary protein and body composition on cardiometabolic health." Thesis, 2020.

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<p>Obesity has ascended to become the primary modifiable cause of death in the United States. New evidence has called into question the utility of BMI – the typical index of obesity – in predicting cardiometabolic disturbances. The distribution of body fatness may be just as important as the total quantity. Intermuscular adipose tissue (IMAT) has emerged as a distinct subset of adipose in skeletal muscle that may be particularly metabolically deleterious. Typically, sections of either the calf or thigh are used as proxy measurements for whole-body IMAT in investigations. However, IMAT dispers
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19

Noblet, Jillian Nicole. "Coronary perivascular adipose tissue and vascular smooth muscle function: influence of obesity." Diss., 2016. http://hdl.handle.net/1805/9815.

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Indiana University-Purdue University Indianapolis (IUPUI)<br>Factors released from coronary perivascular adipose tissue (PVAT), which surrounds large coronary arteries, have been implicated in the development of coronary disease. However, the precise contribution of coronary PVAT-derived factors to the initiation and progression of coronary vascular dysfunction remains ill defined. Accordingly, this investigation was designed to delineate the mechanisms by which PVAT-derived factors influence obesity-induced coronary smooth muscle dysfunction. Isometric tension studies of coronary arteries fro
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20

Chakaroun, Rima. "Effects of weight loss and exercise on chemerin serum concentrations and adipose tissue expression in human obesity." Doctoral thesis, 2014. https://ul.qucosa.de/id/qucosa%3A13074.

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Chemerin is a chemoattractant adipokine that regulates adipogenesis and may induce insulin resistance. Chemerin serum concentrations are elevated in obese, insulin-resistant, and inflammatory states in vivo. Here we investigate the role of omental (OM) and subcutaneous (SC) adipose tissue chemerin and CMKLR1 messenger RNA (mRNA) expression in human obesity. In addition, we test the hypothesis that changes in chemerin serum concentrations are primarily associated with reduced body fat mass in the context of 3 weight loss intervention studies. Chemerin serum concentration was measured in 740 ind
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