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Tesis sobre el tema "BRAT1"

Autor: Grafiati
Publicado: 14 de diciembre de 2024
Última modificación: 31 de julio de 2025

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1

Gordon, Derek, and David Rogoff. "Big Brat." Digital Commons at Loyola Marymount University and Loyola Law School, 2011. https://digitalcommons.lmu.edu/etd/64.

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2

Borneskog, Ida. "Deconstructing the Brat phenomenon." Thesis, Stockholms universitet, Centrum för modevetenskap, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-62776.

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3

Engel, Camille. "Description phénotypique de formes rares de trouble du développement intellectuel et caractérisation des mécanismes moléculaires impliqués." Electronic Thesis or Diss., Bourgogne Franche-Comté, 2024. http://www.theses.fr/2024UBFCE006.

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L’avènement des nouvelles techniques de séquençage a permis d’augmenter de façon considérable le taux diagnostique des troubles du développement intellectuel (TDI) et plus de 2000 gènes impliqués sont aujourd’hui connus. Malgré ces progrès considérables, l’interprétation des variants identifiés par les techniques de séquençage reste parfois difficile et l’histoire naturelle des TDI nouvellement décrits est souvent méconnue. Notre travail a consisté à étudier quatre formes de TDI rares de modes de transmissionvariés sur les plans clinique et génétique afin de mieux comprendre ces affections et
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4

Parker, Richard S. "BRAT - (Blender Rapid Animation Tool)." Thesis, California State University, Long Beach, 2013. http://pqdtopen.proquest.com/#viewpdf?dispub=1523073.

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<p> These are exciting times in the world of computer animation. Individual artists can now produce animations which in the past required teams of artists and programmers to create, but the obstacles to an individual artist can still be daunting in terms of required manual input or technical skills. The goal of this thesis is to demonstrate a simple software tool (BRAT - Blender Rapid Animation Tool) which allows an artist to create cartoon-like 3D animations using the artist's 2D drawings, at the touch of a button. It could be useful for any artist producing 3D animations. The tool is a Pytho
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5

Hunt, Andrew W. "Basic Expeditionary Airfield Resource (BEAR) Requirements Analysis Tool (BRAT)." Quantico, VA : Marine Corps Command and Staff College, 2008. http://handle.dtic.mil/100.2/ADA491134.

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6

Brato, Thorsten [Verfasser]. "A sociophonetic study of Aberdeen English : Innovation and conservatism / Thorsten Brato." Gießen : Universitätsbibliothek, 2012. http://d-nb.info/1064023126/34.

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7

Levesque, Lauren Patricia. "Media Culture, Artifact and Gender Identity: An Analysis of Bratz Dolls." Thesis, University of Ottawa (Canada), 2010. http://hdl.handle.net/10393/28628.

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It could be argued that girl's play is witnessing a drastic transformation. This alteration is fostering much debate surrounding young girls and their notion of self identity. Neil Postman (1982) argues that childhood no longer exists as it has disappeared through the mass media. Likewise, Sharon Lamb (2001, 2006) argues that young girls are continually being sold the ideal attitude and a hyper-sexualized self identity through the media messages and products they consume. Such a problematic transformation raises several concerns with regards to girlhood studies. My research asks how MGA Entert
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8

Bergsager, Håkon, and Erlend Hillestad Bårgard. "Forankring av rørgater i bratt terreng : Forsøk med materialer og metoder." Thesis, Norges teknisk-naturvitenskapelige universitet, Institutt for konstruksjonsteknikk, 2012. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-18767.

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Denne oppgaven tar for seg forankring av nedgravde rørgater. Det er undersøkt interaksjonen mellom rør og jord, først i horisontalt terreng og deretter i bratt terreng med helning over 20 grader. I rapporten er det studert beregningsmodeller som benyttes for beregning av glidestabilitet, motstand mot oppløft og global knekking. Det er sett på både modeller som benyttes i vannkraftbransjen og modeller fra andre fagområder. For å undersøke hvorvidt de ulike beregningsmodellene gjengir virkeligheten ble det i atbeidet med oppgaven utført to typer forsøk. Modellforsøk med rør av polyvinylklorid (P
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9

Bossel, Hans Eirik Anders, and Mats Breien Haugen. "Forankring av rørgater i bratt terreng : Forsøk med materialer og metoder." Thesis, Norges teknisk-naturvitenskapelige universitet, Institutt for bygg, anlegg og transport, 2013. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-22363.

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Denne masteroppgaven omhandler forankring av nedgravde r&#248;rgater i bratt terreng. Oppgaven er en fortsettelse av et samarbeidsprosjekt mellom NVE og Institutt for vann- og milj&#248;teknikk ved NTNU. Det siste &#229;ret er det skrevet en masteroppgave og tre prosjektoppgaver om samme tema.Teorien er basert p&#229; arbeidet i de nevnte oppgavene. Det er presentert fem ulike beregningsmodeller for &#229; beregne stabiliteten for en r&#248;rgate forankret p&#229; friksjon. Modellene blir evaluert med to ulike typer av fors&#248;k, modellfors&#248;k utf&#248;rt i laboratorium og fullskala fors
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10

Brato, Thorsten [Verfasser]. "Variation and Change in Aberdeen English : A Sociophonetic Study / Thorsten Brato." Frankfurt a.M. : Peter Lang GmbH, Internationaler Verlag der Wissenschaften, 2016. http://d-nb.info/1123420548/34.

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11

Kennedy, Melanie. "Bratz, BFFs, princesses and popstars : femininity and celebrity in tween popular culture." Thesis, University of East Anglia, 2012. https://ueaeprints.uea.ac.uk/45684/.

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The last decade has seen a dramatic increase in media output aimed at “tweens” (preadolescent girls), and the expansion more broadly of tween popular culture. This exclusively female preadolescent consumer demographic is seen to emerge alongside a heightened visibility of girls within popular culture since the mid-1990s, and continuing anxieties about girlhood in this intensely mediated environment. However, this burgeoning field has yet to be matched in academic attention. This thesis offers a timely examination of mainstream tween films, television programmes, celebrities and extra-texts fro
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12

Vikström, Eva. "Sverigespel : Kent Anderssons och Bengt Bratts dramatik 1967-71 mot bakgrund av samhälls- och teaterdebatten /." Umeå : Stockholm : Univ. ; Almqvist och Wiksell [distributör], 1989. http://catalogue.bnf.fr/ark:/12148/cb36149740j.

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13

Flaminio, Chiara. "Proposta di traduzione dello script di Brat 2, di Aleksej Balabanov." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2014. http://amslaurea.unibo.it/7190/.

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Il seguente elaborato si propone di fornire un esempio di traduzione del film Brat 2 di Aleksej Balabanov, che possa fungere da base per un eventuale sottotitolaggio. Il lavoro è suddiviso in quattro sezioni: in primo luogo, una breve nota alla traduzione, pensata per favorire una lettura diretta delle battute, in cui ci si soffermerà su alcuni aspetti della lingua e della cultura russe. Le linee orizzontali demarcano i cambi di scena, ovvero il passaggio da un ambiente ad un altro. La seconda sezione si concentra in parte sull'analisi di alcuni temi e caratteristiche del film in questione
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14

Quickelberghe, Y. Van. "Brats, niggers, trembling leaves .motifs and theme in the prose works of Truman Capote." Doctoral thesis, Universite Libre de Bruxelles, 1993. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/212762.

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15

Brath, Manfred [Verfasser], and Detlef [Akademischer Betreuer] Stammer. "Die Dicke von dünnem Meereis bestimmt aus dem Radarrückstreuquerschnitt / Manfred Brath. Betreuer: Detlef Stammer." Hamburg : Staats- und Universitätsbibliothek Hamburg, 2013. http://d-nb.info/1033891436/34.

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16

Harris, Robin. "The role of brat in the differentiation of Drosophilia ovarian stem cells." Thesis, University of Manchester, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.502944.

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17

Queair, Edward C. "Children of the U.S. Military and Identity: A Narrative Inquiry into the "Brat" Experience." Antioch University / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=antioch152935050794055.

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18

Frank, Deborah Jean. "Regulation of cell growth in C. elegans and D. melanogaster by ncl-1/brat /." Thesis, Connect to this title online; UW restricted, 2000. http://hdl.handle.net/1773/5029.

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19

Elagabani, Mohammad Nael [Verfasser]. "NMDA Receptors Control Arf6 Activity via BRAG1 and BRAG2 in Spines of Neuronal Dendrites / Mohammad Nael Elagabani." Berlin : Freie Universität Berlin, 2016. http://d-nb.info/1117541762/34.

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20

O'Donnell, Joshua D. "BRCA1 185delAG Mutant Protein, BRAt, Amplifies Caspase-Mediated Apoptosis and Maspin Expression in Ovarian Cells." [Tampa, Fla] : University of South Florida, 2008. http://purl.fcla.edu/usf/dc/et/SFE0002422.

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21

Bratz, Katharina [Verfasser]. "Effects of antimicrobial feed additives as pre-harvest intervention measure to reduce Campylobacter coli in pigs / Katharina Bratz." Berlin : Freie Universität Berlin, 2015. http://d-nb.info/1076038832/34.

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22

Chandrasekaran, Arunkumar. "Building and Implementing an Inventory Database Model for the Bearcat BRAT Using Microsoft Access Database and C# Programming Language." University of Cincinnati / OhioLINK, 2005. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1131657662.

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23

Awaji, Aeshah. "Utilization of high throughput screening to identify therapeutic targets for defective MCPH1/BRIT1 function-induced premature chromosome condensation in breast and ovarian cancer." Thesis, University of Leeds, 2016. http://etheses.whiterose.ac.uk/13924/.

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Mutations in the N-terminal region of MCPH1/BRIT1 cause premature chromosome condensation (PCC), whereby cells enter mitosis before completing DNA replication. 792 chemical compounds (CC) were selected based on the crystal structure of the N-terminus of MCPH1/BRIT1 and assayed using high throughput- high content imaging to identify CC that induced PCC. Hit validation revealed 4 potential CC, 2 of which induced high PCC at low concentrations. A screen using a human protein kinase (hPK) siRNA sub-library was performed to identify genes that induced PCC. Four hits were selected for validation, ho
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24

Brath, Johannes Michael Stephan Verfasser], Kathleen [Akademischer Betreuer] Herkommer, Kathleen [Gutachter] Herkommer, and Jürgen E. [Gutachter] [Gschwend. "Karzinomspezifisches Überleben nach radikaler Prostatovesikulektomie in Abhängigkeit von Alter und Familienanamnese bei Prostatakarzinomdiagnose / Johannes Michael Stephan Brath ; Gutachter: Kathleen Herkommer, Jürgen E. Gschwend ; Betreuer: Kathleen Herkommer." München : Universitätsbibliothek der TU München, 2017. http://d-nb.info/1150398973/34.

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25

Sångberg, Dennis. "Automated Glioma Segmentation in MRI using Deep Convolutional Networks." Thesis, KTH, Skolan för datavetenskap och kommunikation (CSC), 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-171046.

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Manual segmentation of brain tumours is a time consuming process, results often show high variability, and there is a call for automation in clinical practice. In this thesis the use of deep convolutional networks for automatic glioma segmentation in MRI is investigated. The implemented networks are evaluated on data used in the brain tumor segmentation challenge (BraTS). It is found that 3D convolutional networks generally outperform 2D convolutional networks, and that the best networks can produce segmentations that closely resemble human segmentations. Convolutional networks are also evalua
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26

Linger, Rebecca J. "Novel Roles for 185delAG Mutant BRCA1 in Ovarian Cancer Pathology." Scholar Commons, 2010. http://scholarcommons.usf.edu/etd/3637.

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Familial history is the strongest risk factor for developing ovarian cancer (OC), and a significant contributor to breast cancer risk. Most hereditary breast cancers and OCs are associated with mutation of the tumor suppressor Breast and Ovarian Cancer Susceptibility Gene 1 (BRCA1). Studying risk-associated BRCA1 truncation mutations, such as the founder mutation 185delAG, may reveal signaling pathways important in OC etiology. Recent studies have shown novel BRCA1 mutant functions that may contribute to breast and OC initiation and progression independent of the loss of wtBRCA1. Previously, w
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27

Kargaran, Kobra. "The role of BRCA1 in telomere maintenance." Thesis, Brunel University, 2015. http://bura.brunel.ac.uk/handle/2438/13671.

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Telomeres are fundamental structures found at the end of all eukaryotic chromosomes that function to protect the end of chromosomes from end-to-end fusion, erosion and subsequent telomere dysfunction. Telomerase and alternative lengthening of telomere (ALT) mechanisms maintain the telomeres by compensating natural telomeric loss. ALT is found to be present in 15% of human tumours lines and it may be expressed at low levels in the normal mouse tissues. However, the exact mechanism behind ALT depression and/or activation in the mammalian cells is not fully understood. Previous studies have highl
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28

Vikström, Eva. "Sverigespel : Kent Anderssons och Bengt Bratts dramatik 1967-71 mot bakgrund av samhälls- och teaterdebatten." Doctoral thesis, Umeå universitet, Litteraturvetenskapliga institutionen, 1989. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-67631.

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The dissertation deals with the Municipal Theatre of Göteborg with special reference to the period between 1967 and 1971, during which the group theatre developed and paved the way for a repertoire of social criticism. The theatre debate is viewed against the background of the socio-economic, ideo­logical, and cultural development of the 1960,s. After describing conditions at the Municipal Theatre of Göteborg under Mats Johansson's management from 1962 onwards, the study concentrates on analysing three group theatre plays produced by Lennart Hjulström: Flotten (spring 1967) by Kent Andersson,
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29

Hill, Bridget. "Psychometric Evaluation of the Brachial Assessment Tool for Assessment of Activity Following Traumatic Brachial Plexus Injury." Thesis, Griffith University, 2017. http://hdl.handle.net/10072/366167.

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Brachial plexus Injury (BPI) occurs following trauma to the nerves as they exit the spinal cord in the neck. Dependent on the site and degree of the initial trauma, people with BPI display a board spectrum of ability to use their affected arm to perform day-to-day activities. BPI is a heterogeneous condition that has a significant impact on how the individuals use their arm. Some may only achieve simple stabilising or carrying tasks; others may undertake more complex movements that use the whole arm and hand. Historically, outcomes following adult traumatic BPI have been discussed in terms of
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30

SYLVAIN, VALERIE. "Inhibition de la fonction du gene brca1 par un mutant negatif-dominant brca1 tronque ou par un anti-sens brca1 : implication du gene brac1 dans le developpement tumoral, dans la chimio- et radiosensibilite et dans la regulation transcriptionnelle (doctorat : biologie molecelaire)." Clermont-Ferrand 1, 2001. http://www.theses.fr/2001CLF1MM12.

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31

Khan, Shoukat Yaseen. "History, culture and identity in the novels of Bapsi Sidhwa, Bharati Mukherjee and Hanif Kureishi." Thesis, Tours, 2017. http://www.theses.fr/2017TOUR2018/document.

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L'objectif de cette thèse est d'étudier trois romans écrits par des auteurs anglophones du Pakistan ou de l'Inde, à savoir Bapsi Sidhwa, Bharati Mukherjee et Hanif Kureishi. On pourrait être tenté de placer les trois écrivains de cette étude dans la catégorie «littérature des immigrants». Ils écrivent tous à un moment de migration de masse lorsque l'idée de «choc culturel» parmi les peuples occidentaux commence à être plus évidente. Les trois écrivains sont affectés par des thèmes qui apparaissent seulement de manière marginale dans le débat évoqué ci-dessus, l'accent étant principalement mis
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32

Kristensen, Lars Lyngsgaard Fjord. "Russians abroad in postcommunist cinema." Thesis, University of St Andrews, 2010. http://hdl.handle.net/10023/1015.

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33

Brabenec, Jakub. "Jakub, bratr Páně, v Novém zákoně." Master's thesis, 2020. http://www.nusl.cz/ntk/nusl-409661.

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The thesis follows one of the supporting characters from the New Testament, James, the brother of the Lord. The first chapter deals with the meaning and occurrence of the name James in both biblical and non-biblical sources. The following second chapter deals with the canonical biblical texts that depict fragments of James' life. However, many questions remain about the closer characterization of our wanted person James and the form of his earthly family. The thesis also examines whether James could or could not really be the brother of Jesus of Nazareth. Through the analysis of texts we look
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34

Hsu, Yu-Chen, and 許瑜真. "Role of BMP receptor-associated molecule BRAM1 in BMP signaling." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/07432403229453320294.

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碩士<br>長庚大學<br>基礎醫學研究所<br>92<br>Bone morphogenetic protein induces signals through the stimulation of serine/threonine kinase receptors which phosphorylated BMP signaling mediators, Smad1, Smad5 and Smad4. The phosphorylated Smad1/5/4 complex is then translocated to the nucleus and regulates the BMP target genes. BMP receptor associated molecule 1 (BRAM1) is a molecule that associates with BMP receptor IA. However its role in BMP signaling is still unclear. Thus, the specific aims of this study are examined (1) if BRAM1 affects BMP signaling; (2) If so, are the Smad proteins classical BMP signa
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35

Patel, J. D., Rohitkumar Trivedi, and J. Savalia. "MGA Entertainment, Consumer Entertainment Products Company: Marketing Strategies for ‘Bratz’." 2015. http://hdl.handle.net/10454/15648.

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Yes<br>Toy industry in the US is product driven and full of challenges. This case presents an overview of the California-based Micro Games of America (MGA) Entertainment, which is a consumer entertainment products company, engaged in innovative lines of proprietary and licensed products including toys and games, dolls, consumer electronics, home decor, stationery and sporting goods. It had more than 200 licences. In 2001, MGA launched a fashion doll called ‘Bratz’, and it sold 150 million Bratz dolls all over the world. Bratz line surpassed the legendary brand ‘Barbie’—Mattel, Inc.’s flagship
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36

Wu, Kang-mai, and 鄔康邁. "Role of BRAM1 in BMP signaling examined in zebrafish model and cell lines." Thesis, 2006. http://ndltd.ncl.edu.tw/handle/06388800779595547224.

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博士<br>國立陽明大學<br>微生物及免疫學研究所<br>94<br>BRAM1, bone morphogenetic protein receptor (BMPR) associated molecule 1, is a cytoplasmic protein consisting of 198 amino acids. BRAM1 shares 99% homology with the MYND domain-containing carboxy terminus of a tumor suppressor protein, BS69, which interacts with adenovirus E1A and Epstein-Barr virus-encoded nuclear protein EBNA2 through the MYND domain. Interaction of BS69 with E1A or EBNA2 inhibits viral oncoprotein-mediated transactivation. On the other hand, BRAM1 is a cytoplasmic protein and interacts with BMPR. To date, the biological role of BRAM1 remai
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37

Čašková, Marie. "Vývoj tisku Českobratrské církve evangelické v letech 1968 - 1990 na příkladu měsíčníku Český bratr." Master's thesis, 2010. http://www.nusl.cz/ntk/nusl-295363.

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Diploma thesis "Development of press media of the Evangelical Church of Czech Brethren in the period between 1968 and 1990 shown on the example of the magazine Český bratr" deals with changes of content of the Český bratr magazine during the mentioned period. The magazine is the most important printed periodical medium of the Evangelical Church of Czech Brethren which is the largest non-catholic church in the Czech Republic. The diploma thesis introduces the Evangelical Church of Czech Brethren as the second largest church and the largest prostestant church in the Czech Republic, and besides d
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38

Bravená, Noemi. "Ježíš Kristus, bratr a bližní jednají na mém místě: Zástupnost v teologii Dietricha Bonhoeffera." Doctoral thesis, 2009. http://www.nusl.cz/ntk/nusl-276357.

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The doctoral theses titled by: Jesus Christ, Brother and Neighbour Act in My Place. Deputyship in Dietrich Bonhoeffers Theology presents a contribution to the systematic-theological discussion concerning the relationship theology to deputyship. The submitted work has been divided into eight chapters. First of all, the concept of deputyship is being presented as a burning actual problem together with the current research situation in this field. In addition to that, the submitted paper observes Bonhoeffer thinking in the systematic-theological context. All of the following parts elucidate the c
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39

Kadavá, Anna. "Velký Bratr a my : Jak se konstruuje soukromí v interakci diváka s formátem reality TV." Master's thesis, 2006. http://www.nusl.cz/ntk/nusl-265800.

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The central theme of this diploma is the construction of privacy in reality TV shows. Process design privacy I tried to show with strategies Television text that jsoi in reality TV shows to the formation of private use. The subject of this thesis was illustrated by looking at the three programs listed simultaneously in the Czech Republic (VyVolení Big Brother and Wife Swap), as these resources and methods used and how to participate the resulting experience private audience. Presentation of privacy in these programs I examined as key moments that are offered by their creators audience potentia
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40

Bartová, Nikola. ""Cožpak nejsem člověk a bratr?": Reprezentace otroctví v Západní Indii a abolicionistická rétorika na cestě k emancipaci." Master's thesis, 2015. http://www.nusl.cz/ntk/nusl-347885.

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This thesis is concerned with literature connected with the abolition of slavery in British colonies. The thesis will treat the topic of the abolitionist movement from the perspective of social, cultural and literary history from the beginnings until the abolition of slavery in British colonies in the Caribbean in 1833 with the Slavery Abolition Act. The thesis will focus on the discourse of race and slavery. The chosen authors represent different opinions and perspectives as the discussion will focus on sentimental poetry, travel writings as well as slave narratives. The chief aim is to ident
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41

Chung, Pei-Jung, and 鍾佩蓉. "BMPR-IA binding protein BRAM1 mediates the signal transduction of latent membrane protein 1 of Epstein-Barr virus." Thesis, 2002. http://ndltd.ncl.edu.tw/handle/38924511490931394964.

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博士<br>國防醫學院<br>生命科學研究所<br>91<br>Latent membrane protein 1 (LMP1), a major oncoprotein encoded by Epstein-Barr virus (EBV), has been shown to be involved in cellular signaling pathways. In this thesis, we tried to identify new targets of LMP1 signaling that may help to explain the role of LMP1 in non-lymphocyte cell transformation. Using yeast two-hybrid screening method with the C-terminal sequence of LMP1 as the bait, we found that BMP receptor-associated molecule 1 (BRAM1) associated with LMP1 in vitro and in vivo. This finding was supported by cotransfection experiments and examined by immu
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42

Graves-Morris, Peter R. "BiCGStab, VPAStab and an adaptation to mildly nonlinear systems." 2007. http://hdl.handle.net/10454/3622.

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No<br>The key equations of BiCGStab are summarised to show its connections with Pade and vector-Pade approximation. These considerations lead naturally to stabilised vector-Pade approximation of a vector-valued function (VPAStab), and an algorithm for the acceleration of convergence of a linearly generated sequence of vectors. A generalisation of this algorithm for the acceleration of convergence of a nonlinearly generated system is proposed here, and comparative numerical results are given.
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43

Bratu, Vlad Antonio [Verfasser]. "Histopathological morphometry of human endobronchial biopsies : a comparison of conventional quantitative analyses and stereological designs / vorgelegt von Vlad Antonio Bratu." 2008. http://d-nb.info/999867547/34.

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44

"The Effect of the Rise in Tensions between North Korea and South Korea: American Children Living on American Military Instillations in South Korea." Master's thesis, 2012. http://hdl.handle.net/2286/R.I.14663.

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abstract: American families have been coming to South Korea accompanying active duty service members or Embassy employees since before the Korean War. While their numbers were originally smaller, they continue to increase as South Korean assignments undergo "tour normalization", a transition from a location intended for service members to come alone for one year to a location where service members come accompanied by their family and stay for longer periods of times. The U.S. maintains a large presence in South Korea as a deterrence against possible threats from North Korea. Despite establishm
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Hussain, Rashid. "Exploring metabolic interventions for CIN cancer therapy." Thesis, 2017. http://hdl.handle.net/2440/119191.

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Chromosomal instability (CIN) has been established as one of the hallmarks of cancer, which is prevalent in most of the solid and advanced tumours. CIN enhances genetic heterogeneity in cancer cells. This heterogeneity provides selective advantages to cancer cells against the drugs and the therapies, which are linked to poor prognosis and relapse of cancer. Altered metabolism is another hallmark of cancer, which is being targeted for cancer therapy. In this thesis, I have discussed the therapeutic effect of targeting metabolism in CIN cells and CIN tumours. Chapter 1 is my introduction in whic
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